×

FOLH1 cDNA ORF clone, Homo sapiens (human)

Gene Symbol FOLH1
Entrez Gene ID 2346
Full Name folate hydrolase (prostate-specific membrane antigen) 1
Synonyms FGCP, FOLH, GCP2, GCPII, NAALAD1, NAALAdase, PSM, PSMA, mGCP
General protein information
Preferred Names
glutamate carboxypeptidase 2
Names
glutamate carboxypeptidase 2
NAALADase I
glutamate carboxylase II
glutamate carboxypeptidase II
membrane glutamate carboxypeptidase
cell growth-inhibiting gene 27 protein
folylpoly-gamma-glutamate carboxypeptidase
prostate specific membrane antigen variant F
pteroylpoly-gamma-glutamate carboxypeptidase
N-acetylated alpha-linked acidic dipeptidase 1
N-acetylated-alpha-linked acidic dipeptidase I
NP_001014986.1
NP_001180400.1
NP_001180401.1
NP_001180402.1
NP_004467.1
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

11

11p11.2

Summary This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. Alternative splicing gives rise to multiple transcript variants encoding several different isoforms. [provided by RefSeq, Jul 2010]. lac of sum
Disorder MIM:

600934

Disorder Html:





The following FOLH1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the FOLH1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu57839 XM_011519958 PREDICTED: Homo sapiens folate hydrolase (prostate-specific membrane antigen) 1 (FOLH1), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $319.00
OHu16380 NM_004476 Homo sapiens folate hydrolase (prostate-specific membrane antigen) 1 (FOLH1), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$391.30
$559.00
OHu18015 NM_001193471 Homo sapiens folate hydrolase (prostate-specific membrane antigen) 1 (FOLH1), transcript variant 3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 12-14 Quote Price
OHu16960 NM_001193472 Homo sapiens folate hydrolase (prostate-specific membrane antigen) 1 (FOLH1), transcript variant 4, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 12-14 Quote Price
OHu16871 NM_001193473 Homo sapiens folate hydrolase (prostate-specific membrane antigen) 1 (FOLH1), transcript variant 5, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$223.30
$319.00
OHu16608 NM_001014986 Homo sapiens folate hydrolase (prostate-specific membrane antigen) 1 (FOLH1), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$391.30
$559.00

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu57839
Accession Version XM_011519958.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1422bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product glutamate carboxypeptidase 2 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_009237.19) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGACTGCAG GATCTAGCTA TCCATTGTTT CTGGCCGCCT ATGCGTGCAC TGGGTGTCTG 
GCAGAGAGGC TGGGGTGGTT TATAAAATCC TCCAATGAAG CTACTAACAT TACTCCAAAG
CATAATATGA AAGCATTTTT GGATGAATTG AAAGCTGAGA ACATCAAGAA GTTCTTATAT
AATTTTACAC AGATACCACA TTTAGCAGGA ACAGAACAAA ACTTTCAGCT TGCAAAGCAA
ATTCAATCCC AGTGGAAAGA ATTTGGCCTG GATTCTGTTG AGCTAGCACA TTATGATGTC
CTGTTGTCCT ACCCAAATAA GACTCATCCC AACTACATCT CAATAATTAA TGAAGATGGA
AATGAGATTT TCAACACATC ATTATTTGAA CCACCTCCTC CAGGATATGA AAATGTTTCG
GATATTGTAC CACCTTTCAG TGCTTTCTCT CCTCAAGGAA TGCCAGAGGG CGATCTAGTG
TATGTTAACT ATGCACGAAC TGAAGACTTC TTTAAATTGG AACGGGACAT GAAAATCAAT
TGCTCTGGGA AAATTGTAAT TGCCAGATAT GGGAAAGTTT TCAGAGGAAA TAAGGTTAAA
AATGCCCAGC TGGCAGGGGC CAAAGGAGTC ATTCTCTACT CCGACCCTGC TGACTACTTT
GCTCCTGGGG TGAAGTCCTA TCCAGATGGT TGGAATCTTC CTGGAGGTGG TGTCCAGCGT
GGAAATATCC TAAATCTGAA TGGTGCAGGA GACCCTCTCA CACCAGGTTA CCCAGCAAAT
GAATATGCTT ATAGGCGTGG AATTGCAGAG GCTGTTGGTC TTCCAAGTAT TCCTGTTCAT
CCAATTGGAT ACTATGATGC ACAGAAGCTC CTAGAAAAAA TGGGTGGCTC AGCACCACCA
GATAGCAGCT GGAGAGGAAG TCTCAAAGTG CCCTACAATG TTGGACCTGG CTTTACTGGA
AACTTTTCTA CACAAAAAGT CAAGATGCAC ATCCACTCTA CCAATGAAGT GACAAGAATT
TACAATGTGA TAGGTACTCT CAGAGGAGCA GTGGAACCAG ACAGATATGT CATTCTGGGA
GGTCACCGGG ACTCATGGGT GTTTGGTGGT ATTGACCCTC AGAGTGGAGC AGCTGTTGTT
CATGAAATTG TGAGGAGCTT TGGAACACTG AAAAAGGAAG GGTGGAGACC TAGAAGAACA
ATTTTGTTTG CAAGCTGGGA TGCAGAAGAA TTTGGTCTTC TTGGTTCTAC TGAGTGGGCA
GAGGAGAATT CAAGACTCCT TCAAGAGCGT GGCGTGGCTT ATATTAATGC TGACTCATCT
ATAGAAGGAA ACTACACTCT GAGAGTTGAT TGTACACCGC TGATGTACAG CTTGGTACAC
AACCTAACAA AAGAGGATAA GCAAATTGGG ATCTGGAAAT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqXP_011518260.1
CDS25..1446
Misc Feature(1)151..>321(+)
Misc Feature(2)337..1017(+)
Misc Feature(3)469..786(+)
Misc Feature(4)607..750(+)
Misc Feature(5)793..810(+)
Misc Feature(6)1021..>1419(+)
Misc Feature(7)1108..1338(+)
Translation
Position Chain Variation Link
25 25 a, g dbSNP:2860572
40 40 a, g dbSNP:138010555
61 61 c, g dbSNP:763096537
79 79 g, t dbSNP:530152906
97 97 a, g dbSNP:560406165
99 99 a, g dbSNP:777448978
114 114 c, t dbSNP:146574307
116 116 c, g dbSNP:747681322
124 124 g, t dbSNP:780613989
130 130 a, c dbSNP:754923320
131 131 a, c dbSNP:778887610
147 147 c, t dbSNP:751451081
148 148 a, g dbSNP:779857228
171 171 a, g dbSNP:372054306
186 186 c, t dbSNP:750664447
189 189 a, c dbSNP:368001797
200 200 c, t dbSNP:765488104
202 202 c, t dbSNP:202676
209 209 a, t dbSNP:753306689
217 217 a, g dbSNP:768056036
220 220 a, c dbSNP:367766463
223 223 c, t dbSNP:774791165
233 233 a, g dbSNP:766603573
255 255 c, t dbSNP:761483497
256 256 c, g dbSNP:776233012
278 278 a, g dbSNP:768200390
279 279 g, t dbSNP:746506486
283 283 c, g dbSNP:139621327
287 287 g, t dbSNP:772046975
291 291 c, t dbSNP:745739133
292 292 c, t dbSNP:570533286
300 300 c, t dbSNP:756966079
303 303 a, t dbSNP:547139367
306 306 a, g dbSNP:146289798
312 312 a, t dbSNP:202680
313 313 c, t dbSNP:752820178
333 333 c, g dbSNP:767438602
341 341 a, g dbSNP:369440863
342 342 c, t dbSNP:751970048
347 347 c, g dbSNP:766804724
361 361 a, g dbSNP:377142674
366 366 a, g dbSNP:763279653
374 374 a, g dbSNP:7128652
382 382 a, g dbSNP:267602927
383 383 a, g dbSNP:763728006
390 390 a, g dbSNP:760249223
393 393 g, t dbSNP:780410301
398 398 a, g dbSNP:144409953
399 399 a, c dbSNP:375439459
402 402 a, g dbSNP:199532174
404 404 c, t dbSNP:765524382
406 406 c, t dbSNP:760347053
420 420 a, t dbSNP:752256226
422 422 c, t dbSNP:371189186
423 423 -, a dbSNP:34540261
426 426 a, g dbSNP:767098710
430 430 c, t dbSNP:758949926
432 432 c, t dbSNP:534437382
439 439 a, g dbSNP:770988853
443 443 c, t dbSNP:137879711
444 444 a, g, t dbSNP:377754089
445 445 a, g dbSNP:748441657
448 448 a, g dbSNP:781246950
457 457 c, g dbSNP:138510346
459 459 -, ga dbSNP:768935536
460 460 -, ttc dbSNP:749756788
463 463 a, g dbSNP:747052707
478 478 a, c dbSNP:765937451
482 482 a, g dbSNP:267602926
490 490 a, g dbSNP:780110705
495 495 c, t dbSNP:79155991
496 496 a, g, t dbSNP:778134535
501 501 a, g dbSNP:754599970
516 516 c, t dbSNP:75655145
520 520 c, t dbSNP:377095633
521 521 a, g dbSNP:757958518
525 525 c, t dbSNP:750442389
530 530 a, c dbSNP:765257997
543 543 g, t dbSNP:761741517
544 544 a, g dbSNP:776299190
547 547 c, t dbSNP:75940285
548 548 a, g dbSNP:138028811
551 551 a, g dbSNP:775663569
557 557 a, g dbSNP:772191107
581 581 c, t dbSNP:745938739
591 591 a, g dbSNP:548891620
594 594 c, t dbSNP:774906963
595 595 a, g dbSNP:397834560
596 596 a, c, g dbSNP:749746330
601 601 a, g dbSNP:778021759
607 607 a, c dbSNP:756469525
613 613 a, c dbSNP:746707926
627 627 c, t dbSNP:748517077
632 632 a, g dbSNP:781633225
634 634 a, c, g dbSNP:146923992
639 639 a, g dbSNP:778313935
642 642 g, t dbSNP:756764739
644 644 c, t dbSNP:753772659
645 645 -, c dbSNP:757978540
647 647 a, g dbSNP:540795252
656 656 c, t dbSNP:770894245
666 666 c, t dbSNP:755973727
668 668 a, t dbSNP:752494666
690 690 c, t dbSNP:767244834
692 692 a, g dbSNP:759776753
695 695 -, t dbSNP:752377926
697 697 a, t dbSNP:751741752
700 700 c, g, t dbSNP:763074472
702 702 c, t dbSNP:369820383
711 711 c, g, t dbSNP:182169
712 712 a, g dbSNP:777155090
728 728 a, c, g dbSNP:200342475
737 737 c, t dbSNP:745552201
742 742 c, t dbSNP:201789325
743 743 a, g dbSNP:375565491
753 753 c, t dbSNP:770409404
779 779 c, t dbSNP:748829971
781 781 c, g, t dbSNP:140123322
786 786 a, g dbSNP:752584397
789 789 a, g dbSNP:780996204
793 793 a, t dbSNP:371790405
810 810 c, t dbSNP:76509850
820 820 a, c, t dbSNP:772709942
821 821 a, g dbSNP:116795343
824 824 a, g dbSNP:747651254
829 829 a, g dbSNP:776050215
838 838 a, g dbSNP:768593308
839 839 g, t dbSNP:199756411
842 842 g, t dbSNP:779925727
844 844 c, t dbSNP:758094309
850 850 a, g dbSNP:746148342
856 856 c, t dbSNP:779267530
868 868 a, g dbSNP:199782232
872 872 a, g dbSNP:753976336
873 873 a, g dbSNP:370918056
878 878 a, g dbSNP:544801161
879 879 c, t dbSNP:143206032
880 880 a, g dbSNP:753104799
883 883 a, g dbSNP:767966355
891 891 c, g, t dbSNP:750141457
894 894 c, t dbSNP:764872934
897 897 a, g dbSNP:761397113
903 903 a, c dbSNP:149084901
907 907 a, g dbSNP:781273827
914 914 c, t dbSNP:755461606
917 917 c, t dbSNP:146472302
918 918 a, t dbSNP:780433799
925 925 c, g dbSNP:758736399
926 926 a, g dbSNP:753543878
940 940 a, g dbSNP:143707827
955 955 c, t dbSNP:2851557
957 957 c, g, t dbSNP:149023247
959 959 a, c, g dbSNP:767008939
979 979 a, g dbSNP:200257783
981 981 c, t dbSNP:774399823
989 989 c, t dbSNP:766325948
993 993 c, t dbSNP:144950409
1003 1003 c, g dbSNP:761981128
1010 1010 a, t dbSNP:776887467
1013 1013 a, g dbSNP:768777213
1016 1016 c, t dbSNP:749809918
1022 1022 c, t dbSNP:747084668
1032 1032 a, g dbSNP:775479716
1035 1035 a, g dbSNP:555590356
1038 1038 a, g dbSNP:202716
1052 1052 g, t dbSNP:746340486
1057 1057 a, g dbSNP:376770386
1065 1065 c, t dbSNP:771300656
1067 1067 g, t dbSNP:747804638
1070 1070 g, t dbSNP:780980012
1072 1072 a, g dbSNP:140577100
1073 1073 a, c dbSNP:751121376
1074 1074 a, g dbSNP:375313419
1075 1075 a, g dbSNP:758439576
1087 1087 a, g dbSNP:757072600
1089 1089 a, g dbSNP:556893770
1092 1092 c, t dbSNP:146822849
1094 1094 a, c, t dbSNP:752888961
1095 1095 c, g, t dbSNP:759648885
1098 1098 c, t dbSNP:774787551
1099 1099 c, g dbSNP:539478487
1103 1103 a, g dbSNP:771474698
1111 1111 c, t dbSNP:763312906
1112 1112 a, g dbSNP:199982130
1122 1122 a, g dbSNP:770250830
1125 1125 a, g dbSNP:201886725
1172 1172 c, t dbSNP:746707807
1176 1176 a, g dbSNP:775268651
1180 1180 a, g dbSNP:771545439
1186 1186 c, g dbSNP:745384542
1192 1192 a, c dbSNP:778225999
1196 1196 a, t dbSNP:757243757
1200 1200 c, g dbSNP:749187256
1203 1203 -, t dbSNP:777223627
1206 1206 a, g, t dbSNP:548160675
1241 1241 a, g dbSNP:751037727
1244 1244 a, g dbSNP:765839849
1247 1247 c, t dbSNP:762349547
1248 1248 a, c dbSNP:149765617
1263 1263 c, t dbSNP:764328677
1268 1268 a, g dbSNP:370887055
1288 1288 a, g dbSNP:772733825
1290 1290 a, g dbSNP:571898670
1300 1300 c, t dbSNP:770157136
1302 1302 a, c dbSNP:761785897
1312 1312 c, t dbSNP:776416420
1313 1313 a, g dbSNP:768558882
1318 1318 a, g dbSNP:375484734
1325 1325 a, g dbSNP:779839853
1338 1338 c, t dbSNP:772444946
1339 1339 g, t dbSNP:746046584
1352 1352 a, g dbSNP:764782539
1356 1356 c, g, t dbSNP:201724751
1374 1374 c, t dbSNP:763952088
1379 1379 c, t dbSNP:760611361
1382 1382 c, t dbSNP:139716793
1383 1383 a, g, t dbSNP:370741711
1392 1392 c, t dbSNP:774702332
1396 1396 a, t dbSNP:771203092
1402 1402 c, t dbSNP:61886492
1403 1403 -, a dbSNP:750419915
1407 1407 c, t dbSNP:777855460
1433 1433 a, g dbSNP:140204056
1445 1445 a, g dbSNP:267602925
1466 1466 a, c, t dbSNP:372239425
1468 1468 a, g dbSNP:780894233
1480 1480 c, t dbSNP:754516463
1488 1488 g, t dbSNP:751608388
1493 1493 c, t dbSNP:368939818
1494 1494 c, g dbSNP:758208664
1495 1495 a, g dbSNP:750250735
1496 1496 c, t dbSNP:764896694
1505 1505 a, g dbSNP:757509976
1507 1507 c, t dbSNP:754036827
1510 1510 a, g dbSNP:764214736

Target ORF information:

RefSeq Version XM_011519958
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens folate hydrolase (prostate-specific membrane antigen) 1 (FOLH1), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011519958

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGACTGCAG GATCTAGCTA TCCATTGTTT CTGGCCGCCT ATGCGTGCAC TGGGTGTCTG 
GCAGAGAGGC TGGGGTGGTT TATAAAATCC TCCAATGAAG CTACTAACAT TACTCCAAAG
CATAATATGA AAGCATTTTT GGATGAATTG AAAGCTGAGA ACATCAAGAA GTTCTTATAT
AATTTTACAC AGATACCACA TTTAGCAGGA ACAGAACAAA ACTTTCAGCT TGCAAAGCAA
ATTCAATCCC AGTGGAAAGA ATTTGGCCTG GATTCTGTTG AGCTAGCACA TTATGATGTC
CTGTTGTCCT ACCCAAATAA GACTCATCCC AACTACATCT CAATAATTAA TGAAGATGGA
AATGAGATTT TCAACACATC ATTATTTGAA CCACCTCCTC CAGGATATGA AAATGTTTCG
GATATTGTAC CACCTTTCAG TGCTTTCTCT CCTCAAGGAA TGCCAGAGGG CGATCTAGTG
TATGTTAACT ATGCACGAAC TGAAGACTTC TTTAAATTGG AACGGGACAT GAAAATCAAT
TGCTCTGGGA AAATTGTAAT TGCCAGATAT GGGAAAGTTT TCAGAGGAAA TAAGGTTAAA
AATGCCCAGC TGGCAGGGGC CAAAGGAGTC ATTCTCTACT CCGACCCTGC TGACTACTTT
GCTCCTGGGG TGAAGTCCTA TCCAGATGGT TGGAATCTTC CTGGAGGTGG TGTCCAGCGT
GGAAATATCC TAAATCTGAA TGGTGCAGGA GACCCTCTCA CACCAGGTTA CCCAGCAAAT
GAATATGCTT ATAGGCGTGG AATTGCAGAG GCTGTTGGTC TTCCAAGTAT TCCTGTTCAT
CCAATTGGAT ACTATGATGC ACAGAAGCTC CTAGAAAAAA TGGGTGGCTC AGCACCACCA
GATAGCAGCT GGAGAGGAAG TCTCAAAGTG CCCTACAATG TTGGACCTGG CTTTACTGGA
AACTTTTCTA CACAAAAAGT CAAGATGCAC ATCCACTCTA CCAATGAAGT GACAAGAATT
TACAATGTGA TAGGTACTCT CAGAGGAGCA GTGGAACCAG ACAGATATGT CATTCTGGGA
GGTCACCGGG ACTCATGGGT GTTTGGTGGT ATTGACCCTC AGAGTGGAGC AGCTGTTGTT
CATGAAATTG TGAGGAGCTT TGGAACACTG AAAAAGGAAG GGTGGAGACC TAGAAGAACA
ATTTTGTTTG CAAGCTGGGA TGCAGAAGAA TTTGGTCTTC TTGGTTCTAC TGAGTGGGCA
GAGGAGAATT CAAGACTCCT TCAAGAGCGT GGCGTGGCTT ATATTAATGC TGACTCATCT
ATAGAAGGAA ACTACACTCT GAGAGTTGAT TGTACACCGC TGATGTACAG CTTGGTACAC
AACCTAACAA AAGAGGATAA GCAAATTGGG ATCTGGAAAT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu16380
Accession Version NM_004476.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2253bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product glutamate carboxypeptidase 2 isoform 1
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from M99487.1. Summary: This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. Alternative splicing gives rise to multiple transcript variants encoding several different isoforms. [provided by RefSeq, Jul 2010]. Transcript Variant: This variant (1) encodes the longest isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M99487.1, AK312366.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
ATGTGGAATC TCCTTCACGA AACCGACTCG GCTGTGGCCA CCGCGCGCCG CCCGCGCTGG 
CTGTGCGCTG GGGCGCTGGT GCTGGCGGGT GGCTTCTTTC TCCTCGGCTT CCTCTTCGGG
TGGTTTATAA AATCCTCCAA TGAAGCTACT AACATTACTC CAAAGCATAA TATGAAAGCA
TTTTTGGATG AATTGAAAGC TGAGAACATC AAGAAGTTCT TATATAATTT TACACAGATA
CCACATTTAG CAGGAACAGA ACAAAACTTT CAGCTTGCAA AGCAAATTCA ATCCCAGTGG
AAAGAATTTG GCCTGGATTC TGTTGAGCTA GCACATTATG ATGTCCTGTT GTCCTACCCA
AATAAGACTC ATCCCAACTA CATCTCAATA ATTAATGAAG ATGGAAATGA GATTTTCAAC
ACATCATTAT TTGAACCACC TCCTCCAGGA TATGAAAATG TTTCGGATAT TGTACCACCT
TTCAGTGCTT TCTCTCCTCA AGGAATGCCA GAGGGCGATC TAGTGTATGT TAACTATGCA
CGAACTGAAG ACTTCTTTAA ATTGGAACGG GACATGAAAA TCAATTGCTC TGGGAAAATT
GTAATTGCCA GATATGGGAA AGTTTTCAGA GGAAATAAGG TTAAAAATGC CCAGCTGGCA
GGGGCCAAAG GAGTCATTCT CTACTCCGAC CCTGCTGACT ACTTTGCTCC TGGGGTGAAG
TCCTATCCAG ATGGTTGGAA TCTTCCTGGA GGTGGTGTCC AGCGTGGAAA TATCCTAAAT
CTGAATGGTG CAGGAGACCC TCTCACACCA GGTTACCCAG CAAATGAATA TGCTTATAGG
CGTGGAATTG CAGAGGCTGT TGGTCTTCCA AGTATTCCTG TTCATCCAAT TGGATACTAT
GATGCACAGA AGCTCCTAGA AAAAATGGGT GGCTCAGCAC CACCAGATAG CAGCTGGAGA
GGAAGTCTCA AAGTGCCCTA CAATGTTGGA CCTGGCTTTA CTGGAAACTT TTCTACACAA
AAAGTCAAGA TGCACATCCA CTCTACCAAT GAAGTGACAA GAATTTACAA TGTGATAGGT
ACTCTCAGAG GAGCAGTGGA ACCAGACAGA TATGTCATTC TGGGAGGTCA CCGGGACTCA
TGGGTGTTTG GTGGTATTGA CCCTCAGAGT GGAGCAGCTG TTGTTCATGA AATTGTGAGG
AGCTTTGGAA CACTGAAAAA GGAAGGGTGG AGACCTAGAA GAACAATTTT GTTTGCAAGC
TGGGATGCAG AAGAATTTGG TCTTCTTGGT TCTACTGAGT GGGCAGAGGA GAATTCAAGA
CTCCTTCAAG AGCGTGGCGT GGCTTATATT AATGCTGACT CATCTATAGA AGGAAACTAC
ACTCTGAGAG TTGATTGTAC ACCGCTGATG TACAGCTTGG TACACAACCT AACAAAAGAG
CTGAAAAGCC CTGATGAAGG CTTTGAAGGC AAATCTCTTT ATGAAAGTTG GACTAAAAAA
AGTCCTTCCC CAGAGTTCAG TGGCATGCCC AGGATAAGCA AATTGGGATC TGGAAATGAT
TTTGAGGTGT TCTTCCAACG ACTTGGAATT GCTTCAGGCA GAGCACGGTA TACTAAAAAT
TGGGAAACAA ACAAATTCAG CGGCTATCCA CTGTATCACA GTGTCTATGA AACATATGAG
TTGGTGGAAA AGTTTTATGA TCCAATGTTT AAATATCACC TCACTGTGGC CCAGGTTCGA
GGAGGGATGG TGTTTGAGCT AGCCAATTCC ATAGTGCTCC CTTTTGATTG TCGAGATTAT
GCTGTAGTTT TAAGAAAGTA TGCTGACAAA ATCTACAGTA TTTCTATGAA ACATCCACAG
GAAATGAAGA CATACAGTGT ATCATTTGAT TCACTTTTTT CTGCAGTAAA GAATTTTACA
GAAATTGCTT CCAAGTTCAG TGAGAGACTC CAGGACTTTG ACAAAAGCAA CCCAATAGTA
TTAAGAATGA TGAATGATCA ACTCATGTTT CTGGAAAGAG CATTTATTGA TCCATTAGGG
TTACCAGACA GGCCTTTTTA TAGGCATGTC ATCTATGCTC CAAGCAGCCA CAACAAGTAT
GCAGGGGAGT CATTCCCAGG AATTTATGAT GCTCTGTTTG ATATTGAAAG CAAAGTGGAC
CCTTCCAAGG CCTGGGGAGA AGTGAAGAGA CAGATTTATG TTGCAGCCTT CACAGTGCAG
GCAGCTGCAG AGACTTTGAG TGAAGTAGCC TAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqNP_004467.1
CDS262..2514
Misc Feature(1)166..168(+)
Misc Feature(2)319..390(+)
Misc Feature(3)412..414(+)
Misc Feature(4)433..>603(+)
Misc Feature(5)487..489(+)
Misc Feature(6)619..1299(+)
Misc Feature(7)622..624(+)
Misc Feature(8)679..681(+)
Misc Feature(9)718..720(+)
Misc Feature(10)751..1068(+)
Misc Feature(11)844..846(+)
Misc Feature(12)889..1032(+)
Misc Feature(13)1075..1092(+)
Misc Feature(14)1081..2022(+)
Misc Feature(15)1267..1269(+)
Misc Feature(16)1303..2046(+)
Misc Feature(17)1363..1593(+)
Misc Feature(18)1390..1920(+)
Misc Feature(19)1390..1920(+)
Misc Feature(20)1636..1638(+)
Misc Feature(21)1687..1689(+)
Misc Feature(22)1861..1869(+)
Misc Feature(23)2137..2508(+)
Misc Feature(24)2173..2175(+)
Misc Feature(25)2356..2361(+)
Exon (1)1..379
Gene:FOLH1
Gene Synonym:
Exon (2)380..485
Gene:FOLH1
Gene Synonym:
Exon (3)486..672
Gene:FOLH1
Gene Synonym:
Exon (4)673..774
Gene:FOLH1
Gene Synonym:
Exon (5)775..900
Gene:FOLH1
Gene Synonym:
Exon (6)901..1087
Gene:FOLH1
Gene Synonym:
Exon (7)1088..1181
Gene:FOLH1
Gene Synonym:
Exon (8)1182..1280
Gene:FOLH1
Gene Synonym:
Exon (9)1281..1366
Gene:FOLH1
Gene Synonym:
Exon (10)1367..1486
Gene:FOLH1
Gene Synonym:
Exon (11)1487..1569
Gene:FOLH1
Gene Synonym:
Exon (12)1570..1633
Gene:FOLH1
Gene Synonym:
Exon (13)1634..1701
Gene:FOLH1
Gene Synonym:
Exon (14)1702..1793
Gene:FOLH1
Gene Synonym:
Exon (15)1794..1884
Gene:FOLH1
Gene Synonym:
Exon (16)1885..2149
Gene:FOLH1
Gene Synonym:
Exon (17)2150..2231
Gene:FOLH1
Gene Synonym:
Exon (18)2232..2324
Gene:FOLH1
Gene Synonym:
Exon (19)2325..2635
Gene:FOLH1
Gene Synonym:
Translation
Position Chain Variation Link
20 20 c, t dbSNP:541641740
47 47 c, t dbSNP:779026088
80 80 g, t dbSNP:73473180
113 113 a, g dbSNP:761918085
135 135 c, g dbSNP:556080861
198 198 a, t dbSNP:539348188
212 212 a, g dbSNP:776584552
217 217 c, t dbSNP:368802471
226 226 a, c dbSNP:768289590
233 233 a, c dbSNP:747291464
236 236 a, g dbSNP:780112854
241 241 a, g dbSNP:772239186
244 244 a, g, t dbSNP:779460031
246 246 c, t dbSNP:570144568
247 247 g, t dbSNP:754283916
248 248 c, t dbSNP:553713122
253 253 a, c, t dbSNP:751275631
254 254 c, g dbSNP:765934623
258 258 a, c, g dbSNP:533521065
259 259 a, g dbSNP:764785511
261 261 a, g dbSNP:761867374
271 271 c, t dbSNP:181802264
273 273 c, t dbSNP:768540456
274 274 -, ctt dbSNP:369788403
275 275 -, ttc dbSNP:200069827
279 279 c, g, t dbSNP:775836030
282 282 a, g dbSNP:772177112
286 286 a, g dbSNP:746021500
289 289 c, t dbSNP:778975625
290 290 c, t dbSNP:770948188
292 292 a, g dbSNP:749825495
299 299 c, t dbSNP:778111409
309 309 c, g dbSNP:756559634
315 315 a, g dbSNP:753000475
317 317 a, g dbSNP:781554951
323 323 g, t dbSNP:547930923
331 331 g, t dbSNP:750049863
335 335 a, c dbSNP:764873716
347 347 c, g dbSNP:756800218
349 349 a, g dbSNP:753879892
351 351 g, t dbSNP:763921289
353 353 a, g dbSNP:760582412
361 361 c, g dbSNP:775151051
366 366 a, c dbSNP:767282960
378 378 a, c dbSNP:759774909
381 381 a, g dbSNP:777448978
396 396 c, t dbSNP:146574307
398 398 c, g dbSNP:747681322
406 406 g, t dbSNP:780613989
412 412 a, c dbSNP:754923320
413 413 a, c dbSNP:778887610
429 429 c, t dbSNP:751451081
430 430 a, g dbSNP:779857228
453 453 a, g dbSNP:372054306
468 468 c, t dbSNP:750664447
471 471 a, c dbSNP:368001797
482 482 c, t dbSNP:765488104
484 484 c, t dbSNP:202676
491 491 a, t dbSNP:753306689
499 499 a, g dbSNP:768056036
502 502 a, c dbSNP:367766463
505 505 c, t dbSNP:774791165
515 515 a, g dbSNP:766603573
537 537 c, t dbSNP:761483497
538 538 c, g dbSNP:776233012
560 560 a, g dbSNP:768200390
561 561 g, t dbSNP:746506486
565 565 c, g dbSNP:139621327
569 569 g, t dbSNP:772046975
573 573 c, t dbSNP:745739133
574 574 c, t dbSNP:570533286
582 582 c, t dbSNP:756966079
585 585 a, t dbSNP:547139367
588 588 a, g dbSNP:146289798
594 594 a, t dbSNP:202680
595 595 c, t dbSNP:752820178
615 615 c, g dbSNP:767438602
623 623 a, g dbSNP:369440863
624 624 c, t dbSNP:751970048
629 629 c, g dbSNP:766804724
643 643 a, g dbSNP:377142674
648 648 a, g dbSNP:763279653
656 656 a, g dbSNP:7128652
664 664 a, g dbSNP:267602927
665 665 a, g dbSNP:763728006
672 672 a, g dbSNP:760249223
675 675 g, t dbSNP:780410301
680 680 a, g dbSNP:144409953
681 681 a, c dbSNP:375439459
684 684 a, g dbSNP:199532174
686 686 c, t dbSNP:765524382
688 688 c, t dbSNP:760347053
702 702 a, t dbSNP:752256226
704 704 c, t dbSNP:371189186
705 705 -, a dbSNP:34540261
708 708 a, g dbSNP:767098710
712 712 c, t dbSNP:758949926
714 714 c, t dbSNP:534437382
721 721 a, g dbSNP:770988853
725 725 c, t dbSNP:137879711
726 726 a, g, t dbSNP:377754089
727 727 a, g dbSNP:748441657
730 730 a, g dbSNP:781246950
739 739 c, g dbSNP:138510346
741 741 -, ga dbSNP:768935536
742 742 -, ttc dbSNP:749756788
745 745 a, g dbSNP:747052707
760 760 a, c dbSNP:765937451
764 764 a, g dbSNP:267602926
772 772 a, g dbSNP:780110705
777 777 c, t dbSNP:79155991
778 778 a, g, t dbSNP:778134535
783 783 a, g dbSNP:754599970
798 798 c, t dbSNP:75655145
802 802 c, t dbSNP:377095633
803 803 a, g dbSNP:757958518
807 807 c, t dbSNP:750442389
812 812 a, c dbSNP:765257997
825 825 g, t dbSNP:761741517
826 826 a, g dbSNP:776299190
829 829 c, t dbSNP:75940285
830 830 a, g dbSNP:138028811
833 833 a, g dbSNP:775663569
839 839 a, g dbSNP:772191107
863 863 c, t dbSNP:745938739
873 873 a, g dbSNP:548891620
876 876 c, t dbSNP:774906963
877 877 a, g dbSNP:397834560
878 878 a, c, g dbSNP:749746330
883 883 a, g dbSNP:778021759
889 889 a, c dbSNP:756469525
895 895 a, c dbSNP:746707926
909 909 c, t dbSNP:748517077
914 914 a, g dbSNP:781633225
916 916 a, c, g dbSNP:146923992
921 921 a, g dbSNP:778313935
924 924 g, t dbSNP:756764739
926 926 c, t dbSNP:753772659
927 927 -, c dbSNP:757978540
929 929 a, g dbSNP:540795252
938 938 c, t dbSNP:770894245
948 948 c, t dbSNP:755973727
950 950 a, t dbSNP:752494666
972 972 c, t dbSNP:767244834
974 974 a, g dbSNP:759776753
977 977 -, t dbSNP:752377926
979 979 a, t dbSNP:751741752
982 982 c, g, t dbSNP:763074472
984 984 c, t dbSNP:369820383
993 993 c, g, t dbSNP:182169
994 994 a, g dbSNP:777155090
1010 1010 a, c, g dbSNP:200342475
1019 1019 c, t dbSNP:745552201
1024 1024 c, t dbSNP:201789325
1025 1025 a, g dbSNP:375565491
1035 1035 c, t dbSNP:770409404
1061 1061 c, t dbSNP:748829971
1063 1063 c, g, t dbSNP:140123322
1068 1068 a, g dbSNP:752584397
1071 1071 a, g dbSNP:780996204
1075 1075 a, t dbSNP:371790405
1092 1092 c, t dbSNP:76509850
1102 1102 a, c, t dbSNP:772709942
1103 1103 a, g dbSNP:116795343
1106 1106 a, g dbSNP:747651254
1111 1111 a, g dbSNP:776050215
1120 1120 a, g dbSNP:768593308
1121 1121 g, t dbSNP:199756411
1124 1124 g, t dbSNP:779925727
1126 1126 c, t dbSNP:758094309
1132 1132 a, g dbSNP:746148342
1138 1138 c, t dbSNP:779267530
1150 1150 a, g dbSNP:199782232
1154 1154 a, g dbSNP:753976336
1155 1155 a, g dbSNP:370918056
1160 1160 a, g dbSNP:544801161
1161 1161 c, t dbSNP:143206032
1162 1162 a, g dbSNP:753104799
1165 1165 a, g dbSNP:767966355
1173 1173 c, g, t dbSNP:750141457
1176 1176 c, t dbSNP:764872934
1179 1179 a, g dbSNP:761397113
1185 1185 a, c dbSNP:149084901
1189 1189 a, g dbSNP:781273827
1196 1196 c, t dbSNP:755461606
1199 1199 c, t dbSNP:146472302
1200 1200 a, t dbSNP:780433799
1207 1207 c, g dbSNP:758736399
1208 1208 a, g dbSNP:753543878
1222 1222 a, g dbSNP:143707827
1237 1237 c, t dbSNP:2851557
1239 1239 c, g, t dbSNP:149023247
1241 1241 a, c, g dbSNP:767008939
1261 1261 a, g dbSNP:200257783
1263 1263 c, t dbSNP:774399823
1271 1271 c, t dbSNP:766325948
1275 1275 c, t dbSNP:144950409
1285 1285 c, g dbSNP:761981128
1292 1292 a, t dbSNP:776887467
1295 1295 a, g dbSNP:768777213
1298 1298 c, t dbSNP:749809918
1304 1304 c, t dbSNP:747084668
1314 1314 a, g dbSNP:775479716
1317 1317 a, g dbSNP:555590356
1320 1320 a, g dbSNP:202716
1334 1334 g, t dbSNP:746340486
1339 1339 a, g dbSNP:376770386
1347 1347 c, t dbSNP:771300656
1349 1349 g, t dbSNP:747804638
1352 1352 g, t dbSNP:780980012
1354 1354 a, g dbSNP:140577100
1355 1355 a, c dbSNP:751121376
1356 1356 a, g dbSNP:375313419
1357 1357 a, g dbSNP:758439576
1369 1369 a, g dbSNP:757072600
1371 1371 a, g dbSNP:556893770
1374 1374 c, t dbSNP:146822849
1376 1376 a, c, t dbSNP:752888961
1377 1377 c, g, t dbSNP:759648885
1380 1380 c, t dbSNP:774787551
1381 1381 c, g dbSNP:539478487
1385 1385 a, g dbSNP:771474698
1393 1393 c, t dbSNP:763312906
1394 1394 a, g dbSNP:199982130
1404 1404 a, g dbSNP:770250830
1407 1407 a, g dbSNP:201886725
1454 1454 c, t dbSNP:746707807
1458 1458 a, g dbSNP:775268651
1462 1462 a, g dbSNP:771545439
1468 1468 c, g dbSNP:745384542
1474 1474 a, c dbSNP:778225999
1478 1478 a, t dbSNP:757243757
1482 1482 c, g dbSNP:749187256
1485 1485 -, t dbSNP:777223627
1488 1488 a, g, t dbSNP:548160675
1523 1523 a, g dbSNP:751037727
1526 1526 a, g dbSNP:765839849
1529 1529 c, t dbSNP:762349547
1530 1530 a, c dbSNP:149765617
1545 1545 c, t dbSNP:764328677
1550 1550 a, g dbSNP:370887055
1570 1570 a, g dbSNP:772733825
1572 1572 a, g dbSNP:571898670
1582 1582 c, t dbSNP:770157136
1584 1584 a, c dbSNP:761785897
1594 1594 c, t dbSNP:776416420
1595 1595 a, g dbSNP:768558882
1600 1600 a, g dbSNP:375484734
1607 1607 a, g dbSNP:779839853
1620 1620 c, t dbSNP:772444946
1621 1621 g, t dbSNP:746046584
1634 1634 a, g dbSNP:764782539
1638 1638 c, g, t dbSNP:201724751
1656 1656 c, t dbSNP:763952088
1661 1661 c, t dbSNP:760611361
1664 1664 c, t dbSNP:139716793
1665 1665 a, g, t dbSNP:370741711
1674 1674 c, t dbSNP:774702332
1678 1678 a, t dbSNP:771203092
1684 1684 c, t dbSNP:61886492
1685 1685 -, a dbSNP:750419915
1689 1689 c, t dbSNP:777855460
1716 1716 g, t dbSNP:769888591
1717 1717 g, t dbSNP:748659279
1719 1719 a, t dbSNP:781660664
1729 1729 a, g dbSNP:755407695
1730 1730 a, g dbSNP:142952497
1733 1733 a, g dbSNP:780347923
1743 1743 c, t dbSNP:756890455
1753 1753 a, g, t dbSNP:763560048
1756 1756 a, g dbSNP:755638709
1757 1757 a, g dbSNP:752750462
1762 1762 -, a dbSNP:764290022
1762 1762 a, c, t dbSNP:533663504
1763 1763 -, aac dbSNP:763365445
1763 1763 a, g dbSNP:751426248
1807 1807 a, g dbSNP:140204056
1819 1819 a, g dbSNP:267602925
1840 1840 a, c, t dbSNP:372239425
1842 1842 a, g dbSNP:780894233
1854 1854 c, t dbSNP:754516463
1862 1862 g, t dbSNP:751608388
1867 1867 c, t dbSNP:368939818
1868 1868 c, g dbSNP:758208664
1869 1869 a, g dbSNP:750250735
1870 1870 c, t dbSNP:764896694
1879 1879 a, g dbSNP:757509976
1881 1881 c, t dbSNP:754036827
1884 1884 a, g dbSNP:764214736
1885 1885 a, g dbSNP:766910423
1902 1902 c, t dbSNP:182388588
1903 1903 a, g, t dbSNP:199709866
1908 1908 c, t dbSNP:746598910
1910 1910 c, g dbSNP:775101916
1935 1935 a, t dbSNP:771459907
1943 1943 c, t dbSNP:745876378
1944 1944 a, g dbSNP:778816102
1945 1945 a, g dbSNP:757118184
1953 1953 a, g dbSNP:553564027
1959 1959 a, t dbSNP:777496962
1962 1962 c, t dbSNP:756390079
1966 1966 a, g dbSNP:752832734
1992 1992 c, t dbSNP:781385635
1993 1993 c, t dbSNP:755001634
2019 2019 a, g dbSNP:752182257
2022 2022 a, g dbSNP:767004193
2026 2026 a, g dbSNP:763502164
2036 2036 g, t dbSNP:750845012
2042 2042 c, t dbSNP:765662116
2053 2053 c, t dbSNP:760423374
2054 2054 a, g dbSNP:774991864
2056 2056 a, g dbSNP:771677058
2061 2061 c, t dbSNP:758972352
2064 2064 c, t dbSNP:773794097
2066 2066 c, t dbSNP:567800489
2082 2082 c, t dbSNP:147500653
2083 2083 a, g dbSNP:777584883
2096 2096 a, g dbSNP:769456909
2099 2099 a, g dbSNP:748464478
2100 2100 c, t dbSNP:781269388
2107 2107 a, g dbSNP:755164162
2108 2108 g, t dbSNP:751708654
2119 2119 a, c dbSNP:143235150
2132 2132 a, c dbSNP:759009835
2137 2137 a, g dbSNP:750940557
2138 2138 a, g dbSNP:375836358
2144 2144 c, t dbSNP:762079463
2145 2145 a, c dbSNP:754163774
2148 2148 c, t dbSNP:767089077
2154 2154 a, g dbSNP:137991256
2172 2172 a, g dbSNP:757724515
2173 2173 a, c dbSNP:754177008
2175 2175 c, t dbSNP:535155505
2182 2182 a, g dbSNP:764479615
2188 2188 c, g dbSNP:566020349
2192 2192 a, c dbSNP:546821955
2202 2202 c, t dbSNP:199517010
2205 2205 a, g dbSNP:762448723
2220 2220 c, t dbSNP:144512496
2223 2223 c, t dbSNP:765103565
2234 2234 c, t dbSNP:375948834
2236 2236 a, g dbSNP:757992698
2247 2247 a, g dbSNP:372016808
2256 2256 c, t dbSNP:764768918
2259 2259 c, t dbSNP:761703243
2265 2265 c, g dbSNP:372600008
2273 2273 c, t dbSNP:764045804
2275 2275 g, t dbSNP:760548601
2299 2299 a, g dbSNP:371048605
2301 2301 a, g dbSNP:772445044
2307 2307 a, g dbSNP:746064073
2313 2313 a, g dbSNP:373131146
2314 2314 c, t dbSNP:771023021
2321 2321 a, g dbSNP:749820405
2322 2322 c, t dbSNP:778342843
2341 2341 a, c dbSNP:200462865
2348 2348 a, g dbSNP:149242168
2351 2351 a, g dbSNP:112972107
2352 2352 a, c dbSNP:770985396
2355 2355 c, t dbSNP:763102212
2362 2362 g, t dbSNP:368721018
2368 2368 a, g dbSNP:770312515
2395 2395 c, g dbSNP:748619991
2404 2404 a, g dbSNP:781582032
2406 2406 c, t dbSNP:201855858
2411 2411 a, c, g dbSNP:560179737
2412 2412 a, c dbSNP:150088430
2413 2413 a, g dbSNP:753409936
2430 2430 a, g dbSNP:777377989
2437 2437 a, g dbSNP:756160678
2442 2442 a, t dbSNP:1803128
2459 2459 a, c dbSNP:1803127
2460 2460 c, t dbSNP:752660381
2468 2468 c, t dbSNP:767480479
2471 2471 a, t dbSNP:140860006
2474 2474 c, t dbSNP:759372952
2477 2477 g, t dbSNP:759943723
2489 2489 c, t dbSNP:751249618
2504 2504 a, g dbSNP:550087931
2511 2511 c, g dbSNP:766640846
2516 2516 a, g dbSNP:763040665
2519 2519 a, t dbSNP:773315602
2522 2522 c, t dbSNP:595139
2534 2534 c, t dbSNP:374114868
2535 2535 a, g dbSNP:777116852
2541 2541 a, c dbSNP:768974420
2549 2549 c, t dbSNP:371921219
2578 2578 a, g dbSNP:556881101
2592 2592 c, t dbSNP:186975068

Target ORF information:

RefSeq Version NM_004476
Organism Homo sapiens (human)
Definition Homo sapiens folate hydrolase (prostate-specific membrane antigen) 1 (FOLH1), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_004476

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
ATGTGGAATC TCCTTCACGA AACCGACTCG GCTGTGGCCA CCGCGCGCCG CCCGCGCTGG 
CTGTGCGCTG GGGCGCTGGT GCTGGCGGGT GGCTTCTTTC TCCTCGGCTT CCTCTTCGGG
TGGTTTATAA AATCCTCCAA TGAAGCTACT AACATTACTC CAAAGCATAA TATGAAAGCA
TTTTTGGATG AATTGAAAGC TGAGAACATC AAGAAGTTCT TATATAATTT TACACAGATA
CCACATTTAG CAGGAACAGA ACAAAACTTT CAGCTTGCAA AGCAAATTCA ATCCCAGTGG
AAAGAATTTG GCCTGGATTC TGTTGAGCTA GCACATTATG ATGTCCTGTT GTCCTACCCA
AATAAGACTC ATCCCAACTA CATCTCAATA ATTAATGAAG ATGGAAATGA GATTTTCAAC
ACATCATTAT TTGAACCACC TCCTCCAGGA TATGAAAATG TTTCGGATAT TGTACCACCT
TTCAGTGCTT TCTCTCCTCA AGGAATGCCA GAGGGCGATC TAGTGTATGT TAACTATGCA
CGAACTGAAG ACTTCTTTAA ATTGGAACGG GACATGAAAA TCAATTGCTC TGGGAAAATT
GTAATTGCCA GATATGGGAA AGTTTTCAGA GGAAATAAGG TTAAAAATGC CCAGCTGGCA
GGGGCCAAAG GAGTCATTCT CTACTCCGAC CCTGCTGACT ACTTTGCTCC TGGGGTGAAG
TCCTATCCAG ATGGTTGGAA TCTTCCTGGA GGTGGTGTCC AGCGTGGAAA TATCCTAAAT
CTGAATGGTG CAGGAGACCC TCTCACACCA GGTTACCCAG CAAATGAATA TGCTTATAGG
CGTGGAATTG CAGAGGCTGT TGGTCTTCCA AGTATTCCTG TTCATCCAAT TGGATACTAT
GATGCACAGA AGCTCCTAGA AAAAATGGGT GGCTCAGCAC CACCAGATAG CAGCTGGAGA
GGAAGTCTCA AAGTGCCCTA CAATGTTGGA CCTGGCTTTA CTGGAAACTT TTCTACACAA
AAAGTCAAGA TGCACATCCA CTCTACCAAT GAAGTGACAA GAATTTACAA TGTGATAGGT
ACTCTCAGAG GAGCAGTGGA ACCAGACAGA TATGTCATTC TGGGAGGTCA CCGGGACTCA
TGGGTGTTTG GTGGTATTGA CCCTCAGAGT GGAGCAGCTG TTGTTCATGA AATTGTGAGG
AGCTTTGGAA CACTGAAAAA GGAAGGGTGG AGACCTAGAA GAACAATTTT GTTTGCAAGC
TGGGATGCAG AAGAATTTGG TCTTCTTGGT TCTACTGAGT GGGCAGAGGA GAATTCAAGA
CTCCTTCAAG AGCGTGGCGT GGCTTATATT AATGCTGACT CATCTATAGA AGGAAACTAC
ACTCTGAGAG TTGATTGTAC ACCGCTGATG TACAGCTTGG TACACAACCT AACAAAAGAG
CTGAAAAGCC CTGATGAAGG CTTTGAAGGC AAATCTCTTT ATGAAAGTTG GACTAAAAAA
AGTCCTTCCC CAGAGTTCAG TGGCATGCCC AGGATAAGCA AATTGGGATC TGGAAATGAT
TTTGAGGTGT TCTTCCAACG ACTTGGAATT GCTTCAGGCA GAGCACGGTA TACTAAAAAT
TGGGAAACAA ACAAATTCAG CGGCTATCCA CTGTATCACA GTGTCTATGA AACATATGAG
TTGGTGGAAA AGTTTTATGA TCCAATGTTT AAATATCACC TCACTGTGGC CCAGGTTCGA
GGAGGGATGG TGTTTGAGCT AGCCAATTCC ATAGTGCTCC CTTTTGATTG TCGAGATTAT
GCTGTAGTTT TAAGAAAGTA TGCTGACAAA ATCTACAGTA TTTCTATGAA ACATCCACAG
GAAATGAAGA CATACAGTGT ATCATTTGAT TCACTTTTTT CTGCAGTAAA GAATTTTACA
GAAATTGCTT CCAAGTTCAG TGAGAGACTC CAGGACTTTG ACAAAAGCAA CCCAATAGTA
TTAAGAATGA TGAATGATCA ACTCATGTTT CTGGAAAGAG CATTTATTGA TCCATTAGGG
TTACCAGACA GGCCTTTTTA TAGGCATGTC ATCTATGCTC CAAGCAGCCA CAACAAGTAT
GCAGGGGAGT CATTCCCAGG AATTTATGAT GCTCTGTTTG ATATTGAAAG CAAAGTGGAC
CCTTCCAAGG CCTGGGGAGA AGTGAAGAGA CAGATTTATG TTGCAGCCTT CACAGTGCAG
GCAGCTGCAG AGACTTTGAG TGAAGTAGCC TAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu18015
Accession Version NM_001193471.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2208bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product glutamate carboxypeptidase 2 isoform 3
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from M99487.1 and EF488811.2. This sequence is a reference standard in the RefSeqGene project. Summary: This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. Alternative splicing gives rise to multiple transcript variants encoding several different isoforms. [provided by RefSeq, Jul 2010]. Transcript Variant: This variant (3) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (3) has a shorter and distinct N-terminus compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK295470.1, EF488812.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
ATGACTGCAG GATCTAGCTA TCCATTGTTT CTGGCCGCCT ATGCGTGCAC TGGGTGTCTG 
GCAGAGAGGC TGGGGTGGTT TATAAAATCC TCCAATGAAG CTACTAACAT TACTCCAAAG
CATAATATGA AAGCATTTTT GGATGAATTG AAAGCTGAGA ACATCAAGAA GTTCTTATAT
AATTTTACAC AGATACCACA TTTAGCAGGA ACAGAACAAA ACTTTCAGCT TGCAAAGCAA
ATTCAATCCC AGTGGAAAGA ATTTGGCCTG GATTCTGTTG AGCTAGCACA TTATGATGTC
CTGTTGTCCT ACCCAAATAA GACTCATCCC AACTACATCT CAATAATTAA TGAAGATGGA
AATGAGATTT TCAACACATC ATTATTTGAA CCACCTCCTC CAGGATATGA AAATGTTTCG
GATATTGTAC CACCTTTCAG TGCTTTCTCT CCTCAAGGAA TGCCAGAGGG CGATCTAGTG
TATGTTAACT ATGCACGAAC TGAAGACTTC TTTAAATTGG AACGGGACAT GAAAATCAAT
TGCTCTGGGA AAATTGTAAT TGCCAGATAT GGGAAAGTTT TCAGAGGAAA TAAGGTTAAA
AATGCCCAGC TGGCAGGGGC CAAAGGAGTC ATTCTCTACT CCGACCCTGC TGACTACTTT
GCTCCTGGGG TGAAGTCCTA TCCAGATGGT TGGAATCTTC CTGGAGGTGG TGTCCAGCGT
GGAAATATCC TAAATCTGAA TGGTGCAGGA GACCCTCTCA CACCAGGTTA CCCAGCAAAT
GAATATGCTT ATAGGCGTGG AATTGCAGAG GCTGTTGGTC TTCCAAGTAT TCCTGTTCAT
CCAATTGGAT ACTATGATGC ACAGAAGCTC CTAGAAAAAA TGGGTGGCTC AGCACCACCA
GATAGCAGCT GGAGAGGAAG TCTCAAAGTG CCCTACAATG TTGGACCTGG CTTTACTGGA
AACTTTTCTA CACAAAAAGT CAAGATGCAC ATCCACTCTA CCAATGAAGT GACAAGAATT
TACAATGTGA TAGGTACTCT CAGAGGAGCA GTGGAACCAG ACAGATATGT CATTCTGGGA
GGTCACCGGG ACTCATGGGT GTTTGGTGGT ATTGACCCTC AGAGTGGAGC AGCTGTTGTT
CATGAAATTG TGAGGAGCTT TGGAACACTG AAAAAGGAAG GGTGGAGACC TAGAAGAACA
ATTTTGTTTG CAAGCTGGGA TGCAGAAGAA TTTGGTCTTC TTGGTTCTAC TGAGTGGGCA
GAGGAGAATT CAAGACTCCT TCAAGAGCGT GGCGTGGCTT ATATTAATGC TGACTCATCT
ATAGAAGGAA ACTACACTCT GAGAGTTGAT TGTACACCGC TGATGTACAG CTTGGTACAC
AACCTAACAA AAGAGCTGAA AAGCCCTGAT GAAGGCTTTG AAGGCAAATC TCTTTATGAA
AGTTGGACTA AAAAAAGTCC TTCCCCAGAG TTCAGTGGCA TGCCCAGGAT AAGCAAATTG
GGATCTGGAA ATGATTTTGA GGTGTTCTTC CAACGACTTG GAATTGCTTC AGGCAGAGCA
CGGTATACTA AAAATTGGGA AACAAACAAA TTCAGCGGCT ATCCACTGTA TCACAGTGTC
TATGAAACAT ATGAGTTGGT GGAAAAGTTT TATGATCCAA TGTTTAAATA TCACCTCACT
GTGGCCCAGG TTCGAGGAGG GATGGTGTTT GAGCTAGCCA ATTCCATAGT GCTCCCTTTT
GATTGTCGAG ATTATGCTGT AGTTTTAAGA AAGTATGCTG ACAAAATCTA CAGTATTTCT
ATGAAACATC CACAGGAAAT GAAGACATAC AGTGTATCAT TTGATTCACT TTTTTCTGCA
GTAAAGAATT TTACAGAAAT TGCTTCCAAG TTCAGTGAGA GACTCCAGGA CTTTGACAAA
AGCAACCCAA TAGTATTAAG AATGATGAAT GATCAACTCA TGTTTCTGGA AAGAGCATTT
ATTGATCCAT TAGGGTTACC AGACAGGCCT TTTTATAGGC ATGTCATCTA TGCTCCAAGC
AGCCACAACA AGTATGCAGG GGAGTCATTC CCAGGAATTT ATGATGCTCT GTTTGATATT
GAAAGCAAAG TGGACCCTTC CAAGGCCTGG GGAGAAGTGA AGAGACAGAT TTATGTTGCA
GCCTTCACAG TGCAGGCAGC TGCAGAGACT TTGAGTGAAG TAGCCTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqNP_001180400.1
CDS404..2611
Misc Feature(1)209..211(+)
Misc Feature(2)530..>700(+)
Misc Feature(3)716..1396(+)
Misc Feature(4)848..1165(+)
Misc Feature(5)986..1129(+)
Misc Feature(6)1172..1189(+)
Misc Feature(7)1400..2143(+)
Misc Feature(8)1460..1690(+)
Misc Feature(9)1487..2017(+)
Misc Feature(10)1487..2017(+)
Misc Feature(11)2234..2605(+)
Exon (1)1..379
Gene:FOLH1
Gene Synonym:
Exon (2)380..476
Gene:FOLH1
Gene Synonym:
Exon (3)477..582
Gene:FOLH1
Gene Synonym:
Exon (4)583..769
Gene:FOLH1
Gene Synonym:
Exon (5)770..871
Gene:FOLH1
Gene Synonym:
Exon (6)872..997
Gene:FOLH1
Gene Synonym:
Exon (7)998..1184
Gene:FOLH1
Gene Synonym:
Exon (8)1185..1278
Gene:FOLH1
Gene Synonym:
Exon (9)1279..1377
Gene:FOLH1
Gene Synonym:
Exon (10)1378..1463
Gene:FOLH1
Gene Synonym:
Exon (11)1464..1583
Gene:FOLH1
Gene Synonym:
Exon (12)1584..1666
Gene:FOLH1
Gene Synonym:
Exon (13)1667..1730
Gene:FOLH1
Gene Synonym:
Exon (14)1731..1798
Gene:FOLH1
Gene Synonym:
Exon (15)1799..1890
Gene:FOLH1
Gene Synonym:
Exon (16)1891..1981
Gene:FOLH1
Gene Synonym:
Exon (17)1982..2246
Gene:FOLH1
Gene Synonym:
Exon (18)2247..2328
Gene:FOLH1
Gene Synonym:
Exon (19)2329..2421
Gene:FOLH1
Gene Synonym:
Exon (20)2422..2732
Gene:FOLH1
Gene Synonym:
Translation
Position Chain Variation Link
20 20 c, t dbSNP:541641740
47 47 c, t dbSNP:779026088
80 80 g, t dbSNP:73473180
113 113 a, g dbSNP:761918085
135 135 c, g dbSNP:556080861
198 198 a, t dbSNP:539348188
212 212 a, g dbSNP:776584552
217 217 c, t dbSNP:368802471
226 226 a, c dbSNP:768289590
233 233 a, c dbSNP:747291464
236 236 a, g dbSNP:780112854
241 241 a, g dbSNP:772239186
244 244 a, g, t dbSNP:779460031
246 246 c, t dbSNP:570144568
247 247 g, t dbSNP:754283916
248 248 c, t dbSNP:553713122
253 253 a, c, t dbSNP:751275631
254 254 c, g dbSNP:765934623
258 258 a, c, g dbSNP:533521065
259 259 a, g dbSNP:764785511
261 261 a, g dbSNP:761867374
271 271 c, t dbSNP:181802264
273 273 c, t dbSNP:768540456
274 274 -, ctt dbSNP:369788403
275 275 -, ttc dbSNP:200069827
279 279 c, g, t dbSNP:775836030
282 282 a, g dbSNP:772177112
286 286 a, g dbSNP:746021500
289 289 c, t dbSNP:778975625
290 290 c, t dbSNP:770948188
292 292 a, g dbSNP:749825495
299 299 c, t dbSNP:778111409
309 309 c, g dbSNP:756559634
315 315 a, g dbSNP:753000475
317 317 a, g dbSNP:781554951
323 323 g, t dbSNP:547930923
331 331 g, t dbSNP:750049863
335 335 a, c dbSNP:764873716
347 347 c, g dbSNP:756800218
349 349 a, g dbSNP:753879892
351 351 g, t dbSNP:763921289
353 353 a, g dbSNP:760582412
361 361 c, g dbSNP:775151051
366 366 a, c dbSNP:767282960
378 378 a, c dbSNP:759774909
404 404 a, g dbSNP:2860572
419 419 a, g dbSNP:138010555
440 440 c, g dbSNP:763096537
458 458 g, t dbSNP:530152906
476 476 a, g dbSNP:560406165
478 478 a, g dbSNP:777448978
493 493 c, t dbSNP:146574307
495 495 c, g dbSNP:747681322
503 503 g, t dbSNP:780613989
509 509 a, c dbSNP:754923320
510 510 a, c dbSNP:778887610
526 526 c, t dbSNP:751451081
527 527 a, g dbSNP:779857228
550 550 a, g dbSNP:372054306
565 565 c, t dbSNP:750664447
568 568 a, c dbSNP:368001797
579 579 c, t dbSNP:765488104
581 581 c, t dbSNP:202676
588 588 a, t dbSNP:753306689
596 596 a, g dbSNP:768056036
599 599 a, c dbSNP:367766463
602 602 c, t dbSNP:774791165
612 612 a, g dbSNP:766603573
634 634 c, t dbSNP:761483497
635 635 c, g dbSNP:776233012
657 657 a, g dbSNP:768200390
658 658 g, t dbSNP:746506486
662 662 c, g dbSNP:139621327
666 666 g, t dbSNP:772046975
670 670 c, t dbSNP:745739133
671 671 c, t dbSNP:570533286
679 679 c, t dbSNP:756966079
682 682 a, t dbSNP:547139367
685 685 a, g dbSNP:146289798
691 691 a, t dbSNP:202680
692 692 c, t dbSNP:752820178
712 712 c, g dbSNP:767438602
720 720 a, g dbSNP:369440863
721 721 c, t dbSNP:751970048
726 726 c, g dbSNP:766804724
740 740 a, g dbSNP:377142674
745 745 a, g dbSNP:763279653
753 753 a, g dbSNP:7128652
761 761 a, g dbSNP:267602927
762 762 a, g dbSNP:763728006
769 769 a, g dbSNP:760249223
772 772 g, t dbSNP:780410301
777 777 a, g dbSNP:144409953
778 778 a, c dbSNP:375439459
781 781 a, g dbSNP:199532174
783 783 c, t dbSNP:765524382
785 785 c, t dbSNP:760347053
799 799 a, t dbSNP:752256226
801 801 c, t dbSNP:371189186
802 802 -, a dbSNP:34540261
805 805 a, g dbSNP:767098710
809 809 c, t dbSNP:758949926
811 811 c, t dbSNP:534437382
818 818 a, g dbSNP:770988853
822 822 c, t dbSNP:137879711
823 823 a, g, t dbSNP:377754089
824 824 a, g dbSNP:748441657
827 827 a, g dbSNP:781246950
836 836 c, g dbSNP:138510346
838 838 -, ga dbSNP:768935536
839 839 -, ttc dbSNP:749756788
842 842 a, g dbSNP:747052707
857 857 a, c dbSNP:765937451
861 861 a, g dbSNP:267602926
869 869 a, g dbSNP:780110705
874 874 c, t dbSNP:79155991
875 875 a, g, t dbSNP:778134535
880 880 a, g dbSNP:754599970
895 895 c, t dbSNP:75655145
899 899 c, t dbSNP:377095633
900 900 a, g dbSNP:757958518
904 904 c, t dbSNP:750442389
909 909 a, c dbSNP:765257997
922 922 g, t dbSNP:761741517
923 923 a, g dbSNP:776299190
926 926 c, t dbSNP:75940285
927 927 a, g dbSNP:138028811
930 930 a, g dbSNP:775663569
936 936 a, g dbSNP:772191107
960 960 c, t dbSNP:745938739
970 970 a, g dbSNP:548891620
973 973 c, t dbSNP:774906963
974 974 a, g dbSNP:397834560
975 975 a, c, g dbSNP:749746330
980 980 a, g dbSNP:778021759
986 986 a, c dbSNP:756469525
992 992 a, c dbSNP:746707926
1006 1006 c, t dbSNP:748517077
1011 1011 a, g dbSNP:781633225
1013 1013 a, c, g dbSNP:146923992
1018 1018 a, g dbSNP:778313935
1021 1021 g, t dbSNP:756764739
1023 1023 c, t dbSNP:753772659
1024 1024 -, c dbSNP:757978540
1026 1026 a, g dbSNP:540795252
1035 1035 c, t dbSNP:770894245
1045 1045 c, t dbSNP:755973727
1047 1047 a, t dbSNP:752494666
1069 1069 c, t dbSNP:767244834
1071 1071 a, g dbSNP:759776753
1074 1074 -, t dbSNP:752377926
1076 1076 a, t dbSNP:751741752
1079 1079 c, g, t dbSNP:763074472
1081 1081 c, t dbSNP:369820383
1090 1090 c, g, t dbSNP:182169
1091 1091 a, g dbSNP:777155090
1107 1107 a, c, g dbSNP:200342475
1116 1116 c, t dbSNP:745552201
1121 1121 c, t dbSNP:201789325
1122 1122 a, g dbSNP:375565491
1132 1132 c, t dbSNP:770409404
1158 1158 c, t dbSNP:748829971
1160 1160 c, g, t dbSNP:140123322
1165 1165 a, g dbSNP:752584397
1168 1168 a, g dbSNP:780996204
1172 1172 a, t dbSNP:371790405
1189 1189 c, t dbSNP:76509850
1199 1199 a, c, t dbSNP:772709942
1200 1200 a, g dbSNP:116795343
1203 1203 a, g dbSNP:747651254
1208 1208 a, g dbSNP:776050215
1217 1217 a, g dbSNP:768593308
1218 1218 g, t dbSNP:199756411
1221 1221 g, t dbSNP:779925727
1223 1223 c, t dbSNP:758094309
1229 1229 a, g dbSNP:746148342
1235 1235 c, t dbSNP:779267530
1247 1247 a, g dbSNP:199782232
1251 1251 a, g dbSNP:753976336
1252 1252 a, g dbSNP:370918056
1257 1257 a, g dbSNP:544801161
1258 1258 c, t dbSNP:143206032
1259 1259 a, g dbSNP:753104799
1262 1262 a, g dbSNP:767966355
1270 1270 c, g, t dbSNP:750141457
1273 1273 c, t dbSNP:764872934
1276 1276 a, g dbSNP:761397113
1282 1282 a, c dbSNP:149084901
1286 1286 a, g dbSNP:781273827
1293 1293 c, t dbSNP:755461606
1296 1296 c, t dbSNP:146472302
1297 1297 a, t dbSNP:780433799
1304 1304 c, g dbSNP:758736399
1305 1305 a, g dbSNP:753543878
1319 1319 a, g dbSNP:143707827
1334 1334 c, t dbSNP:2851557
1336 1336 c, g, t dbSNP:149023247
1338 1338 a, c, g dbSNP:767008939
1358 1358 a, g dbSNP:200257783
1360 1360 c, t dbSNP:774399823
1368 1368 c, t dbSNP:766325948
1372 1372 c, t dbSNP:144950409
1382 1382 c, g dbSNP:761981128
1389 1389 a, t dbSNP:776887467
1392 1392 a, g dbSNP:768777213
1395 1395 c, t dbSNP:749809918
1401 1401 c, t dbSNP:747084668
1411 1411 a, g dbSNP:775479716
1414 1414 a, g dbSNP:555590356
1417 1417 a, g dbSNP:202716
1431 1431 g, t dbSNP:746340486
1436 1436 a, g dbSNP:376770386
1444 1444 c, t dbSNP:771300656
1446 1446 g, t dbSNP:747804638
1449 1449 g, t dbSNP:780980012
1451 1451 a, g dbSNP:140577100
1452 1452 a, c dbSNP:751121376
1453 1453 a, g dbSNP:375313419
1454 1454 a, g dbSNP:758439576
1466 1466 a, g dbSNP:757072600
1468 1468 a, g dbSNP:556893770
1471 1471 c, t dbSNP:146822849
1473 1473 a, c, t dbSNP:752888961
1474 1474 c, g, t dbSNP:759648885
1477 1477 c, t dbSNP:774787551
1478 1478 c, g dbSNP:539478487
1482 1482 a, g dbSNP:771474698
1490 1490 c, t dbSNP:763312906
1491 1491 a, g dbSNP:199982130
1501 1501 a, g dbSNP:770250830
1504 1504 a, g dbSNP:201886725
1551 1551 c, t dbSNP:746707807
1555 1555 a, g dbSNP:775268651
1559 1559 a, g dbSNP:771545439
1565 1565 c, g dbSNP:745384542
1571 1571 a, c dbSNP:778225999
1575 1575 a, t dbSNP:757243757
1579 1579 c, g dbSNP:749187256
1582 1582 -, t dbSNP:777223627
1585 1585 a, g, t dbSNP:548160675
1620 1620 a, g dbSNP:751037727
1623 1623 a, g dbSNP:765839849
1626 1626 c, t dbSNP:762349547
1627 1627 a, c dbSNP:149765617
1642 1642 c, t dbSNP:764328677
1647 1647 a, g dbSNP:370887055
1667 1667 a, g dbSNP:772733825
1669 1669 a, g dbSNP:571898670
1679 1679 c, t dbSNP:770157136
1681 1681 a, c dbSNP:761785897
1691 1691 c, t dbSNP:776416420
1692 1692 a, g dbSNP:768558882
1697 1697 a, g dbSNP:375484734
1704 1704 a, g dbSNP:779839853
1717 1717 c, t dbSNP:772444946
1718 1718 g, t dbSNP:746046584
1731 1731 a, g dbSNP:764782539
1735 1735 c, g, t dbSNP:201724751
1753 1753 c, t dbSNP:763952088
1758 1758 c, t dbSNP:760611361
1761 1761 c, t dbSNP:139716793
1762 1762 a, g, t dbSNP:370741711
1771 1771 c, t dbSNP:774702332
1775 1775 a, t dbSNP:771203092
1781 1781 c, t dbSNP:61886492
1782 1782 -, a dbSNP:750419915
1786 1786 c, t dbSNP:777855460
1813 1813 g, t dbSNP:769888591
1814 1814 g, t dbSNP:748659279
1816 1816 a, t dbSNP:781660664
1826 1826 a, g dbSNP:755407695
1827 1827 a, g dbSNP:142952497
1830 1830 a, g dbSNP:780347923
1840 1840 c, t dbSNP:756890455
1850 1850 a, g, t dbSNP:763560048
1853 1853 a, g dbSNP:755638709
1854 1854 a, g dbSNP:752750462
1859 1859 -, a dbSNP:764290022
1859 1859 a, c, t dbSNP:533663504
1860 1860 -, aac dbSNP:763365445
1860 1860 a, g dbSNP:751426248
1904 1904 a, g dbSNP:140204056
1916 1916 a, g dbSNP:267602925
1937 1937 a, c, t dbSNP:372239425
1939 1939 a, g dbSNP:780894233
1951 1951 c, t dbSNP:754516463
1959 1959 g, t dbSNP:751608388
1964 1964 c, t dbSNP:368939818
1965 1965 c, g dbSNP:758208664
1966 1966 a, g dbSNP:750250735
1967 1967 c, t dbSNP:764896694
1976 1976 a, g dbSNP:757509976
1978 1978 c, t dbSNP:754036827
1981 1981 a, g dbSNP:764214736
1982 1982 a, g dbSNP:766910423
1999 1999 c, t dbSNP:182388588
2000 2000 a, g, t dbSNP:199709866
2005 2005 c, t dbSNP:746598910
2007 2007 c, g dbSNP:775101916
2032 2032 a, t dbSNP:771459907
2040 2040 c, t dbSNP:745876378
2041 2041 a, g dbSNP:778816102
2042 2042 a, g dbSNP:757118184
2050 2050 a, g dbSNP:553564027
2056 2056 a, t dbSNP:777496962
2059 2059 c, t dbSNP:756390079
2063 2063 a, g dbSNP:752832734
2089 2089 c, t dbSNP:781385635
2090 2090 c, t dbSNP:755001634
2116 2116 a, g dbSNP:752182257
2119 2119 a, g dbSNP:767004193
2123 2123 a, g dbSNP:763502164
2133 2133 g, t dbSNP:750845012
2139 2139 c, t dbSNP:765662116
2150 2150 c, t dbSNP:760423374
2151 2151 a, g dbSNP:774991864
2153 2153 a, g dbSNP:771677058
2158 2158 c, t dbSNP:758972352
2161 2161 c, t dbSNP:773794097
2163 2163 c, t dbSNP:567800489
2179 2179 c, t dbSNP:147500653
2180 2180 a, g dbSNP:777584883
2193 2193 a, g dbSNP:769456909
2196 2196 a, g dbSNP:748464478
2197 2197 c, t dbSNP:781269388
2204 2204 a, g dbSNP:755164162
2205 2205 g, t dbSNP:751708654
2216 2216 a, c dbSNP:143235150
2229 2229 a, c dbSNP:759009835
2234 2234 a, g dbSNP:750940557
2235 2235 a, g dbSNP:375836358
2241 2241 c, t dbSNP:762079463
2242 2242 a, c dbSNP:754163774
2245 2245 c, t dbSNP:767089077
2251 2251 a, g dbSNP:137991256
2269 2269 a, g dbSNP:757724515
2270 2270 a, c dbSNP:754177008
2272 2272 c, t dbSNP:535155505
2279 2279 a, g dbSNP:764479615
2285 2285 c, g dbSNP:566020349
2289 2289 a, c dbSNP:546821955
2299 2299 c, t dbSNP:199517010
2302 2302 a, g dbSNP:762448723
2317 2317 c, t dbSNP:144512496
2320 2320 c, t dbSNP:765103565
2331 2331 c, t dbSNP:375948834
2333 2333 a, g dbSNP:757992698
2344 2344 a, g dbSNP:372016808
2353 2353 c, t dbSNP:764768918
2356 2356 c, t dbSNP:761703243
2362 2362 c, g dbSNP:372600008
2370 2370 c, t dbSNP:764045804
2372 2372 g, t dbSNP:760548601
2396 2396 a, g dbSNP:371048605
2398 2398 a, g dbSNP:772445044
2404 2404 a, g dbSNP:746064073
2410 2410 a, g dbSNP:373131146
2411 2411 c, t dbSNP:771023021
2418 2418 a, g dbSNP:749820405
2419 2419 c, t dbSNP:778342843
2438 2438 a, c dbSNP:200462865
2445 2445 a, g dbSNP:149242168
2448 2448 a, g dbSNP:112972107
2449 2449 a, c dbSNP:770985396
2452 2452 c, t dbSNP:763102212
2459 2459 g, t dbSNP:368721018
2465 2465 a, g dbSNP:770312515
2492 2492 c, g dbSNP:748619991
2501 2501 a, g dbSNP:781582032
2503 2503 c, t dbSNP:201855858
2508 2508 a, c, g dbSNP:560179737
2509 2509 a, c dbSNP:150088430
2510 2510 a, g dbSNP:753409936
2527 2527 a, g dbSNP:777377989
2534 2534 a, g dbSNP:756160678
2539 2539 a, t dbSNP:1803128
2556 2556 a, c dbSNP:1803127
2557 2557 c, t dbSNP:752660381
2565 2565 c, t dbSNP:767480479
2568 2568 a, t dbSNP:140860006
2571 2571 c, t dbSNP:759372952
2574 2574 g, t dbSNP:759943723
2586 2586 c, t dbSNP:751249618
2601 2601 a, g dbSNP:550087931
2608 2608 c, g dbSNP:766640846
2613 2613 a, g dbSNP:763040665
2616 2616 a, t dbSNP:773315602
2619 2619 c, t dbSNP:595139
2631 2631 c, t dbSNP:374114868
2632 2632 a, g dbSNP:777116852
2638 2638 a, c dbSNP:768974420
2646 2646 c, t dbSNP:371921219
2675 2675 a, g dbSNP:556881101
2689 2689 c, t dbSNP:186975068

Target ORF information:

RefSeq Version NM_001193471
Organism Homo sapiens (human)
Definition Homo sapiens folate hydrolase (prostate-specific membrane antigen) 1 (FOLH1), transcript variant 3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001193471

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
ATGACTGCAG GATCTAGCTA TCCATTGTTT CTGGCCGCCT ATGCGTGCAC TGGGTGTCTG 
GCAGAGAGGC TGGGGTGGTT TATAAAATCC TCCAATGAAG CTACTAACAT TACTCCAAAG
CATAATATGA AAGCATTTTT GGATGAATTG AAAGCTGAGA ACATCAAGAA GTTCTTATAT
AATTTTACAC AGATACCACA TTTAGCAGGA ACAGAACAAA ACTTTCAGCT TGCAAAGCAA
ATTCAATCCC AGTGGAAAGA ATTTGGCCTG GATTCTGTTG AGCTAGCACA TTATGATGTC
CTGTTGTCCT ACCCAAATAA GACTCATCCC AACTACATCT CAATAATTAA TGAAGATGGA
AATGAGATTT TCAACACATC ATTATTTGAA CCACCTCCTC CAGGATATGA AAATGTTTCG
GATATTGTAC CACCTTTCAG TGCTTTCTCT CCTCAAGGAA TGCCAGAGGG CGATCTAGTG
TATGTTAACT ATGCACGAAC TGAAGACTTC TTTAAATTGG AACGGGACAT GAAAATCAAT
TGCTCTGGGA AAATTGTAAT TGCCAGATAT GGGAAAGTTT TCAGAGGAAA TAAGGTTAAA
AATGCCCAGC TGGCAGGGGC CAAAGGAGTC ATTCTCTACT CCGACCCTGC TGACTACTTT
GCTCCTGGGG TGAAGTCCTA TCCAGATGGT TGGAATCTTC CTGGAGGTGG TGTCCAGCGT
GGAAATATCC TAAATCTGAA TGGTGCAGGA GACCCTCTCA CACCAGGTTA CCCAGCAAAT
GAATATGCTT ATAGGCGTGG AATTGCAGAG GCTGTTGGTC TTCCAAGTAT TCCTGTTCAT
CCAATTGGAT ACTATGATGC ACAGAAGCTC CTAGAAAAAA TGGGTGGCTC AGCACCACCA
GATAGCAGCT GGAGAGGAAG TCTCAAAGTG CCCTACAATG TTGGACCTGG CTTTACTGGA
AACTTTTCTA CACAAAAAGT CAAGATGCAC ATCCACTCTA CCAATGAAGT GACAAGAATT
TACAATGTGA TAGGTACTCT CAGAGGAGCA GTGGAACCAG ACAGATATGT CATTCTGGGA
GGTCACCGGG ACTCATGGGT GTTTGGTGGT ATTGACCCTC AGAGTGGAGC AGCTGTTGTT
CATGAAATTG TGAGGAGCTT TGGAACACTG AAAAAGGAAG GGTGGAGACC TAGAAGAACA
ATTTTGTTTG CAAGCTGGGA TGCAGAAGAA TTTGGTCTTC TTGGTTCTAC TGAGTGGGCA
GAGGAGAATT CAAGACTCCT TCAAGAGCGT GGCGTGGCTT ATATTAATGC TGACTCATCT
ATAGAAGGAA ACTACACTCT GAGAGTTGAT TGTACACCGC TGATGTACAG CTTGGTACAC
AACCTAACAA AAGAGCTGAA AAGCCCTGAT GAAGGCTTTG AAGGCAAATC TCTTTATGAA
AGTTGGACTA AAAAAAGTCC TTCCCCAGAG TTCAGTGGCA TGCCCAGGAT AAGCAAATTG
GGATCTGGAA ATGATTTTGA GGTGTTCTTC CAACGACTTG GAATTGCTTC AGGCAGAGCA
CGGTATACTA AAAATTGGGA AACAAACAAA TTCAGCGGCT ATCCACTGTA TCACAGTGTC
TATGAAACAT ATGAGTTGGT GGAAAAGTTT TATGATCCAA TGTTTAAATA TCACCTCACT
GTGGCCCAGG TTCGAGGAGG GATGGTGTTT GAGCTAGCCA ATTCCATAGT GCTCCCTTTT
GATTGTCGAG ATTATGCTGT AGTTTTAAGA AAGTATGCTG ACAAAATCTA CAGTATTTCT
ATGAAACATC CACAGGAAAT GAAGACATAC AGTGTATCAT TTGATTCACT TTTTTCTGCA
GTAAAGAATT TTACAGAAAT TGCTTCCAAG TTCAGTGAGA GACTCCAGGA CTTTGACAAA
AGCAACCCAA TAGTATTAAG AATGATGAAT GATCAACTCA TGTTTCTGGA AAGAGCATTT
ATTGATCCAT TAGGGTTACC AGACAGGCCT TTTTATAGGC ATGTCATCTA TGCTCCAAGC
AGCCACAACA AGTATGCAGG GGAGTCATTC CCAGGAATTT ATGATGCTCT GTTTGATATT
GAAAGCAAAG TGGACCCTTC CAAGGCCTGG GGAGAAGTGA AGAGACAGAT TTATGTTGCA
GCCTTCACAG TGCAGGCAGC TGCAGAGACT TTGAGTGAAG TAGCCTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu16960
Accession Version NM_001193472.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2115bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product glutamate carboxypeptidase 2 isoform 4
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from M99487.1, EF488811.2 and BC025672.1. Summary: This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. Alternative splicing gives rise to multiple transcript variants encoding several different isoforms. [provided by RefSeq, Jul 2010]. Transcript Variant: This variant (4) differs in the 5' UTR and coding sequence and lacks an alternate in-frame exon compared to variant 1. The resulting isoform (4) has a shorter and distinct N-terminus and lacks an internal segment compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: EF488811.2 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
ATGACTGCAG GATCTAGCTA TCCATTGTTT CTGGCCGCCT ATGCGTGCAC TGGGTGTCTG 
GCAGAGAGGC TGGGGTGGTT TATAAAATCC TCCAATGAAG CTACTAACAT TACTCCAAAG
CATAATATGA AAGCATTTTT GGATGAATTG AAAGCTGAGA ACATCAAGAA GTTCTTATAT
AATTTTACAC AGATACCACA TTTAGCAGGA ACAGAACAAA ACTTTCAGCT TGCAAAGCAA
ATTCAATCCC AGTGGAAAGA ATTTGGCCTG GATTCTGTTG AGCTAGCACA TTATGATGTC
CTGTTGTCCT ACCCAAATAA GACTCATCCC AACTACATCT CAATAATTAA TGAAGATGGA
AATGAGATTT TCAACACATC ATTATTTGAA CCACCTCCTC CAGGATATGA AAATGTTTCG
GATATTGTAC CACCTTTCAG TGCTTTCTCT CCTCAAGGAA TGCCAGAGGG CGATCTAGTG
TATGTTAACT ATGCACGAAC TGAAGACTTC TTTAAATTGG AACGGGACAT GAAAATCAAT
TGCTCTGGGA AAATTGTAAT TGCCAGATAT GGGAAAGTTT TCAGAGGAAA TAAGGTTAAA
AATGCCCAGC TGGCAGGGGC CAAAGGAGTC ATTCTCTACT CCGACCCTGC TGACTACTTT
GCTCCTGGGG TGAAGTCCTA TCCAGATGGT TGGAATCTTC CTGGAGGTGG TGTCCAGCGT
GGAAATATCC TAAATCTGAA TGGTGCAGGA GACCCTCTCA CACCAGGTTA CCCAGCAAAT
GAATATGCTT ATAGGCGTGG AATTGCAGAG GCTGTTGGTC TTCCAAGTAT TCCTGTTCAT
CCAATTGGAT ACTATGATGC ACAGAAGCTC CTAGAAAAAA TGGGTGGCTC AGCACCACCA
GATAGCAGCT GGAGAGGAAG TCTCAAAGTG CCCTACAATG TTGGACCTGG CTTTACTGGA
AACTTTTCTA CACAAAAAGT CAAGATGCAC ATCCACTCTA CCAATGAAGT GACAAGAATT
TACAATGTGA TAGGTACTCT CAGAGGAGCA GTGGAACCAG ACAGATATGT CATTCTGGGA
GGTCACCGGG ACTCATGGGT GTTTGGTGGT ATTGACCCTC AGAGTGGAGC AGCTGTTGTT
CATGAAATTG TGAGGAGCTT TGGAACACTG AAAAAGGAAG GGTGGAGACC TAGAAGAACA
ATTTTGTTTG CAAGCTGGGA TGCAGAAGAA TTTGGTCTTC TTGGTTCTAC TGAGTGGGCA
GAGGAGAATT CAAGACTCCT TCAAGAGCGT GGCGTGGCTT ATATTAATGC TGACTCATCT
ATAGAAGGAA ACTACACTCT GAGAGTTGAT TGTACACCGC TGATGTACAG CTTGGTACAC
AACCTAACAA AAGAGCTGAA AAGCCCTGAT GAAGGCTTTG AAGGCAAATC TCTTTATGAA
AGTTGGACTA AAAAAAGTCC TTCCCCAGAG TTCAGTGGCA TGCCCAGGAT AAGCAAATTG
GGATCTGGAA ATGATTTTGA GGTGTTCTTC CAACGACTTG GAATTGCTTC AGGCAGAGCA
CGGTATACTA AAAATTGGGA AACAAACAAA TTCAGCGGCT ATCCACTGTA TCACAGTGTC
TATGAAACAT ATGAGTTGGT GGAAAAGTTT TATGATCCAA TGTTTAAATA TCACCTCACT
GTGGCCCAGG TTCGAGGAGG GATGGTGTTT GAGCTAGCCA ATTCCATAGT GCTCCCTTTT
GATTGTCGAG ATTATGCTGT AGTTTTAAGA AAGTATGCTG ACAAAATCTA CAGTATTTCT
ATGAAACATC CACAGGAAAT GAAGACATAC AGTGTATCAT TTGATTCACT TTTTTCTGCA
GTAAAGAATT TTACAGAAAT TGCTTCCAAG TTCAGTGAGA GACTCCAGGA CTTTGACAAA
AGCAAGCATG TCATCTATGC TCCAAGCAGC CACAACAAGT ATGCAGGGGA GTCATTCCCA
GGAATTTATG ATGCTCTGTT TGATATTGAA AGCAAAGTGG ACCCTTCCAA GGCCTGGGGA
GAAGTGAAGA GACAGATTTA TGTTGCAGCC TTCACAGTGC AGGCAGCTGC AGAGACTTTG
AGTGAAGTAG CCTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqNP_001180401.1
CDS404..2518
Misc Feature(1)209..211(+)
Misc Feature(2)530..>700(+)
Misc Feature(3)716..1396(+)
Misc Feature(4)848..1165(+)
Misc Feature(5)986..1129(+)
Misc Feature(6)1172..1189(+)
Misc Feature(7)1400..2143(+)
Misc Feature(8)1460..1690(+)
Misc Feature(9)1487..2017(+)
Misc Feature(10)1487..2017(+)
Misc Feature(11)2234..2512(+)
Exon (1)1..379
Gene:FOLH1
Gene Synonym:
Exon (2)380..476
Gene:FOLH1
Gene Synonym:
Exon (3)477..582
Gene:FOLH1
Gene Synonym:
Exon (4)583..769
Gene:FOLH1
Gene Synonym:
Exon (5)770..871
Gene:FOLH1
Gene Synonym:
Exon (6)872..997
Gene:FOLH1
Gene Synonym:
Exon (7)998..1184
Gene:FOLH1
Gene Synonym:
Exon (8)1185..1278
Gene:FOLH1
Gene Synonym:
Exon (9)1279..1377
Gene:FOLH1
Gene Synonym:
Exon (10)1378..1463
Gene:FOLH1
Gene Synonym:
Exon (11)1464..1583
Gene:FOLH1
Gene Synonym:
Exon (12)1584..1666
Gene:FOLH1
Gene Synonym:
Exon (13)1667..1730
Gene:FOLH1
Gene Synonym:
Exon (14)1731..1798
Gene:FOLH1
Gene Synonym:
Exon (15)1799..1890
Gene:FOLH1
Gene Synonym:
Exon (16)1891..1981
Gene:FOLH1
Gene Synonym:
Exon (17)1982..2246
Gene:FOLH1
Gene Synonym:
Exon (18)2247..2328
Gene:FOLH1
Gene Synonym:
Exon (19)2329..2639
Gene:FOLH1
Gene Synonym:
Translation
Position Chain Variation Link
20 20 c, t dbSNP:541641740
47 47 c, t dbSNP:779026088
80 80 g, t dbSNP:73473180
113 113 a, g dbSNP:761918085
135 135 c, g dbSNP:556080861
198 198 a, t dbSNP:539348188
212 212 a, g dbSNP:776584552
217 217 c, t dbSNP:368802471
226 226 a, c dbSNP:768289590
233 233 a, c dbSNP:747291464
236 236 a, g dbSNP:780112854
241 241 a, g dbSNP:772239186
244 244 a, g, t dbSNP:779460031
246 246 c, t dbSNP:570144568
247 247 g, t dbSNP:754283916
248 248 c, t dbSNP:553713122
253 253 a, c, t dbSNP:751275631
254 254 c, g dbSNP:765934623
258 258 a, c, g dbSNP:533521065
259 259 a, g dbSNP:764785511
261 261 a, g dbSNP:761867374
271 271 c, t dbSNP:181802264
273 273 c, t dbSNP:768540456
274 274 -, ctt dbSNP:369788403
275 275 -, ttc dbSNP:200069827
279 279 c, g, t dbSNP:775836030
282 282 a, g dbSNP:772177112
286 286 a, g dbSNP:746021500
289 289 c, t dbSNP:778975625
290 290 c, t dbSNP:770948188
292 292 a, g dbSNP:749825495
299 299 c, t dbSNP:778111409
309 309 c, g dbSNP:756559634
315 315 a, g dbSNP:753000475
317 317 a, g dbSNP:781554951
323 323 g, t dbSNP:547930923
331 331 g, t dbSNP:750049863
335 335 a, c dbSNP:764873716
347 347 c, g dbSNP:756800218
349 349 a, g dbSNP:753879892
351 351 g, t dbSNP:763921289
353 353 a, g dbSNP:760582412
361 361 c, g dbSNP:775151051
366 366 a, c dbSNP:767282960
378 378 a, c dbSNP:759774909
404 404 a, g dbSNP:2860572
419 419 a, g dbSNP:138010555
440 440 c, g dbSNP:763096537
458 458 g, t dbSNP:530152906
476 476 a, g dbSNP:560406165
478 478 a, g dbSNP:777448978
493 493 c, t dbSNP:146574307
495 495 c, g dbSNP:747681322
503 503 g, t dbSNP:780613989
509 509 a, c dbSNP:754923320
510 510 a, c dbSNP:778887610
526 526 c, t dbSNP:751451081
527 527 a, g dbSNP:779857228
550 550 a, g dbSNP:372054306
565 565 c, t dbSNP:750664447
568 568 a, c dbSNP:368001797
579 579 c, t dbSNP:765488104
581 581 c, t dbSNP:202676
588 588 a, t dbSNP:753306689
596 596 a, g dbSNP:768056036
599 599 a, c dbSNP:367766463
602 602 c, t dbSNP:774791165
612 612 a, g dbSNP:766603573
634 634 c, t dbSNP:761483497
635 635 c, g dbSNP:776233012
657 657 a, g dbSNP:768200390
658 658 g, t dbSNP:746506486
662 662 c, g dbSNP:139621327
666 666 g, t dbSNP:772046975
670 670 c, t dbSNP:745739133
671 671 c, t dbSNP:570533286
679 679 c, t dbSNP:756966079
682 682 a, t dbSNP:547139367
685 685 a, g dbSNP:146289798
691 691 a, t dbSNP:202680
692 692 c, t dbSNP:752820178
712 712 c, g dbSNP:767438602
720 720 a, g dbSNP:369440863
721 721 c, t dbSNP:751970048
726 726 c, g dbSNP:766804724
740 740 a, g dbSNP:377142674
745 745 a, g dbSNP:763279653
753 753 a, g dbSNP:7128652
761 761 a, g dbSNP:267602927
762 762 a, g dbSNP:763728006
769 769 a, g dbSNP:760249223
772 772 g, t dbSNP:780410301
777 777 a, g dbSNP:144409953
778 778 a, c dbSNP:375439459
781 781 a, g dbSNP:199532174
783 783 c, t dbSNP:765524382
785 785 c, t dbSNP:760347053
799 799 a, t dbSNP:752256226
801 801 c, t dbSNP:371189186
802 802 -, a dbSNP:34540261
805 805 a, g dbSNP:767098710
809 809 c, t dbSNP:758949926
811 811 c, t dbSNP:534437382
818 818 a, g dbSNP:770988853
822 822 c, t dbSNP:137879711
823 823 a, g, t dbSNP:377754089
824 824 a, g dbSNP:748441657
827 827 a, g dbSNP:781246950
836 836 c, g dbSNP:138510346
838 838 -, ga dbSNP:768935536
839 839 -, ttc dbSNP:749756788
842 842 a, g dbSNP:747052707
857 857 a, c dbSNP:765937451
861 861 a, g dbSNP:267602926
869 869 a, g dbSNP:780110705
874 874 c, t dbSNP:79155991
875 875 a, g, t dbSNP:778134535
880 880 a, g dbSNP:754599970
895 895 c, t dbSNP:75655145
899 899 c, t dbSNP:377095633
900 900 a, g dbSNP:757958518
904 904 c, t dbSNP:750442389
909 909 a, c dbSNP:765257997
922 922 g, t dbSNP:761741517
923 923 a, g dbSNP:776299190
926 926 c, t dbSNP:75940285
927 927 a, g dbSNP:138028811
930 930 a, g dbSNP:775663569
936 936 a, g dbSNP:772191107
960 960 c, t dbSNP:745938739
970 970 a, g dbSNP:548891620
973 973 c, t dbSNP:774906963
974 974 a, g dbSNP:397834560
975 975 a, c, g dbSNP:749746330
980 980 a, g dbSNP:778021759
986 986 a, c dbSNP:756469525
992 992 a, c dbSNP:746707926
1006 1006 c, t dbSNP:748517077
1011 1011 a, g dbSNP:781633225
1013 1013 a, c, g dbSNP:146923992
1018 1018 a, g dbSNP:778313935
1021 1021 g, t dbSNP:756764739
1023 1023 c, t dbSNP:753772659
1024 1024 -, c dbSNP:757978540
1026 1026 a, g dbSNP:540795252
1035 1035 c, t dbSNP:770894245
1045 1045 c, t dbSNP:755973727
1047 1047 a, t dbSNP:752494666
1069 1069 c, t dbSNP:767244834
1071 1071 a, g dbSNP:759776753
1074 1074 -, t dbSNP:752377926
1076 1076 a, t dbSNP:751741752
1079 1079 c, g, t dbSNP:763074472
1081 1081 c, t dbSNP:369820383
1090 1090 c, g, t dbSNP:182169
1091 1091 a, g dbSNP:777155090
1107 1107 a, c, g dbSNP:200342475
1116 1116 c, t dbSNP:745552201
1121 1121 c, t dbSNP:201789325
1122 1122 a, g dbSNP:375565491
1132 1132 c, t dbSNP:770409404
1158 1158 c, t dbSNP:748829971
1160 1160 c, g, t dbSNP:140123322
1165 1165 a, g dbSNP:752584397
1168 1168 a, g dbSNP:780996204
1172 1172 a, t dbSNP:371790405
1189 1189 c, t dbSNP:76509850
1199 1199 a, c, t dbSNP:772709942
1200 1200 a, g dbSNP:116795343
1203 1203 a, g dbSNP:747651254
1208 1208 a, g dbSNP:776050215
1217 1217 a, g dbSNP:768593308
1218 1218 g, t dbSNP:199756411
1221 1221 g, t dbSNP:779925727
1223 1223 c, t dbSNP:758094309
1229 1229 a, g dbSNP:746148342
1235 1235 c, t dbSNP:779267530
1247 1247 a, g dbSNP:199782232
1251 1251 a, g dbSNP:753976336
1252 1252 a, g dbSNP:370918056
1257 1257 a, g dbSNP:544801161
1258 1258 c, t dbSNP:143206032
1259 1259 a, g dbSNP:753104799
1262 1262 a, g dbSNP:767966355
1270 1270 c, g, t dbSNP:750141457
1273 1273 c, t dbSNP:764872934
1276 1276 a, g dbSNP:761397113
1282 1282 a, c dbSNP:149084901
1286 1286 a, g dbSNP:781273827
1293 1293 c, t dbSNP:755461606
1296 1296 c, t dbSNP:146472302
1297 1297 a, t dbSNP:780433799
1304 1304 c, g dbSNP:758736399
1305 1305 a, g dbSNP:753543878
1319 1319 a, g dbSNP:143707827
1334 1334 c, t dbSNP:2851557
1336 1336 c, g, t dbSNP:149023247
1338 1338 a, c, g dbSNP:767008939
1358 1358 a, g dbSNP:200257783
1360 1360 c, t dbSNP:774399823
1368 1368 c, t dbSNP:766325948
1372 1372 c, t dbSNP:144950409
1382 1382 c, g dbSNP:761981128
1389 1389 a, t dbSNP:776887467
1392 1392 a, g dbSNP:768777213
1395 1395 c, t dbSNP:749809918
1401 1401 c, t dbSNP:747084668
1411 1411 a, g dbSNP:775479716
1414 1414 a, g dbSNP:555590356
1417 1417 a, g dbSNP:202716
1431 1431 g, t dbSNP:746340486
1436 1436 a, g dbSNP:376770386
1444 1444 c, t dbSNP:771300656
1446 1446 g, t dbSNP:747804638
1449 1449 g, t dbSNP:780980012
1451 1451 a, g dbSNP:140577100
1452 1452 a, c dbSNP:751121376
1453 1453 a, g dbSNP:375313419
1454 1454 a, g dbSNP:758439576
1466 1466 a, g dbSNP:757072600
1468 1468 a, g dbSNP:556893770
1471 1471 c, t dbSNP:146822849
1473 1473 a, c, t dbSNP:752888961
1474 1474 c, g, t dbSNP:759648885
1477 1477 c, t dbSNP:774787551
1478 1478 c, g dbSNP:539478487
1482 1482 a, g dbSNP:771474698
1490 1490 c, t dbSNP:763312906
1491 1491 a, g dbSNP:199982130
1501 1501 a, g dbSNP:770250830
1504 1504 a, g dbSNP:201886725
1551 1551 c, t dbSNP:746707807
1555 1555 a, g dbSNP:775268651
1559 1559 a, g dbSNP:771545439
1565 1565 c, g dbSNP:745384542
1571 1571 a, c dbSNP:778225999
1575 1575 a, t dbSNP:757243757
1579 1579 c, g dbSNP:749187256
1582 1582 -, t dbSNP:777223627
1585 1585 a, g, t dbSNP:548160675
1620 1620 a, g dbSNP:751037727
1623 1623 a, g dbSNP:765839849
1626 1626 c, t dbSNP:762349547
1627 1627 a, c dbSNP:149765617
1642 1642 c, t dbSNP:764328677
1647 1647 a, g dbSNP:370887055
1667 1667 a, g dbSNP:772733825
1669 1669 a, g dbSNP:571898670
1679 1679 c, t dbSNP:770157136
1681 1681 a, c dbSNP:761785897
1691 1691 c, t dbSNP:776416420
1692 1692 a, g dbSNP:768558882
1697 1697 a, g dbSNP:375484734
1704 1704 a, g dbSNP:779839853
1717 1717 c, t dbSNP:772444946
1718 1718 g, t dbSNP:746046584
1731 1731 a, g dbSNP:764782539
1735 1735 c, g, t dbSNP:201724751
1753 1753 c, t dbSNP:763952088
1758 1758 c, t dbSNP:760611361
1761 1761 c, t dbSNP:139716793
1762 1762 a, g, t dbSNP:370741711
1771 1771 c, t dbSNP:774702332
1775 1775 a, t dbSNP:771203092
1781 1781 c, t dbSNP:61886492
1782 1782 -, a dbSNP:750419915
1786 1786 c, t dbSNP:777855460
1813 1813 g, t dbSNP:769888591
1814 1814 g, t dbSNP:748659279
1816 1816 a, t dbSNP:781660664
1826 1826 a, g dbSNP:755407695
1827 1827 a, g dbSNP:142952497
1830 1830 a, g dbSNP:780347923
1840 1840 c, t dbSNP:756890455
1850 1850 a, g, t dbSNP:763560048
1853 1853 a, g dbSNP:755638709
1854 1854 a, g dbSNP:752750462
1859 1859 -, a dbSNP:764290022
1859 1859 a, c, t dbSNP:533663504
1860 1860 -, aac dbSNP:763365445
1860 1860 a, g dbSNP:751426248
1904 1904 a, g dbSNP:140204056
1916 1916 a, g dbSNP:267602925
1937 1937 a, c, t dbSNP:372239425
1939 1939 a, g dbSNP:780894233
1951 1951 c, t dbSNP:754516463
1959 1959 g, t dbSNP:751608388
1964 1964 c, t dbSNP:368939818
1965 1965 c, g dbSNP:758208664
1966 1966 a, g dbSNP:750250735
1967 1967 c, t dbSNP:764896694
1976 1976 a, g dbSNP:757509976
1978 1978 c, t dbSNP:754036827
1981 1981 a, g dbSNP:764214736
1982 1982 a, g dbSNP:766910423
1999 1999 c, t dbSNP:182388588
2000 2000 a, g, t dbSNP:199709866
2005 2005 c, t dbSNP:746598910
2007 2007 c, g dbSNP:775101916
2032 2032 a, t dbSNP:771459907
2040 2040 c, t dbSNP:745876378
2041 2041 a, g dbSNP:778816102
2042 2042 a, g dbSNP:757118184
2050 2050 a, g dbSNP:553564027
2056 2056 a, t dbSNP:777496962
2059 2059 c, t dbSNP:756390079
2063 2063 a, g dbSNP:752832734
2089 2089 c, t dbSNP:781385635
2090 2090 c, t dbSNP:755001634
2116 2116 a, g dbSNP:752182257
2119 2119 a, g dbSNP:767004193
2123 2123 a, g dbSNP:763502164
2133 2133 g, t dbSNP:750845012
2139 2139 c, t dbSNP:765662116
2150 2150 c, t dbSNP:760423374
2151 2151 a, g dbSNP:774991864
2153 2153 a, g dbSNP:771677058
2158 2158 c, t dbSNP:758972352
2161 2161 c, t dbSNP:773794097
2163 2163 c, t dbSNP:567800489
2179 2179 c, t dbSNP:147500653
2180 2180 a, g dbSNP:777584883
2193 2193 a, g dbSNP:769456909
2196 2196 a, g dbSNP:748464478
2197 2197 c, t dbSNP:781269388
2204 2204 a, g dbSNP:755164162
2205 2205 g, t dbSNP:751708654
2216 2216 a, c dbSNP:143235150
2229 2229 a, c dbSNP:759009835
2234 2234 a, g dbSNP:750940557
2235 2235 a, g dbSNP:375836358
2241 2241 c, t dbSNP:762079463
2242 2242 a, c dbSNP:754163774
2245 2245 c, t dbSNP:767089077
2251 2251 a, g dbSNP:137991256
2269 2269 a, g dbSNP:757724515
2270 2270 a, c dbSNP:754177008
2272 2272 c, t dbSNP:535155505
2279 2279 a, g dbSNP:764479615
2285 2285 c, g dbSNP:566020349
2289 2289 a, c dbSNP:546821955
2299 2299 c, t dbSNP:199517010
2302 2302 a, g dbSNP:762448723
2317 2317 c, t dbSNP:144512496
2320 2320 c, t dbSNP:765103565
2345 2345 a, c dbSNP:200462865
2352 2352 a, g dbSNP:149242168
2355 2355 a, g dbSNP:112972107
2356 2356 a, c dbSNP:770985396
2359 2359 c, t dbSNP:763102212
2366 2366 g, t dbSNP:368721018
2372 2372 a, g dbSNP:770312515
2399 2399 c, g dbSNP:748619991
2408 2408 a, g dbSNP:781582032
2410 2410 c, t dbSNP:201855858
2415 2415 a, c, g dbSNP:560179737
2416 2416 a, c dbSNP:150088430
2417 2417 a, g dbSNP:753409936
2434 2434 a, g dbSNP:777377989
2441 2441 a, g dbSNP:756160678
2446 2446 a, t dbSNP:1803128
2463 2463 a, c dbSNP:1803127
2464 2464 c, t dbSNP:752660381
2472 2472 c, t dbSNP:767480479
2475 2475 a, t dbSNP:140860006
2478 2478 c, t dbSNP:759372952
2481 2481 g, t dbSNP:759943723
2493 2493 c, t dbSNP:751249618
2508 2508 a, g dbSNP:550087931
2515 2515 c, g dbSNP:766640846
2520 2520 a, g dbSNP:763040665
2523 2523 a, t dbSNP:773315602
2526 2526 c, t dbSNP:595139
2538 2538 c, t dbSNP:374114868
2539 2539 a, g dbSNP:777116852
2545 2545 a, c dbSNP:768974420
2553 2553 c, t dbSNP:371921219
2582 2582 a, g dbSNP:556881101
2596 2596 c, t dbSNP:186975068

Target ORF information:

RefSeq Version NM_001193472
Organism Homo sapiens (human)
Definition Homo sapiens folate hydrolase (prostate-specific membrane antigen) 1 (FOLH1), transcript variant 4, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001193472

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
ATGACTGCAG GATCTAGCTA TCCATTGTTT CTGGCCGCCT ATGCGTGCAC TGGGTGTCTG 
GCAGAGAGGC TGGGGTGGTT TATAAAATCC TCCAATGAAG CTACTAACAT TACTCCAAAG
CATAATATGA AAGCATTTTT GGATGAATTG AAAGCTGAGA ACATCAAGAA GTTCTTATAT
AATTTTACAC AGATACCACA TTTAGCAGGA ACAGAACAAA ACTTTCAGCT TGCAAAGCAA
ATTCAATCCC AGTGGAAAGA ATTTGGCCTG GATTCTGTTG AGCTAGCACA TTATGATGTC
CTGTTGTCCT ACCCAAATAA GACTCATCCC AACTACATCT CAATAATTAA TGAAGATGGA
AATGAGATTT TCAACACATC ATTATTTGAA CCACCTCCTC CAGGATATGA AAATGTTTCG
GATATTGTAC CACCTTTCAG TGCTTTCTCT CCTCAAGGAA TGCCAGAGGG CGATCTAGTG
TATGTTAACT ATGCACGAAC TGAAGACTTC TTTAAATTGG AACGGGACAT GAAAATCAAT
TGCTCTGGGA AAATTGTAAT TGCCAGATAT GGGAAAGTTT TCAGAGGAAA TAAGGTTAAA
AATGCCCAGC TGGCAGGGGC CAAAGGAGTC ATTCTCTACT CCGACCCTGC TGACTACTTT
GCTCCTGGGG TGAAGTCCTA TCCAGATGGT TGGAATCTTC CTGGAGGTGG TGTCCAGCGT
GGAAATATCC TAAATCTGAA TGGTGCAGGA GACCCTCTCA CACCAGGTTA CCCAGCAAAT
GAATATGCTT ATAGGCGTGG AATTGCAGAG GCTGTTGGTC TTCCAAGTAT TCCTGTTCAT
CCAATTGGAT ACTATGATGC ACAGAAGCTC CTAGAAAAAA TGGGTGGCTC AGCACCACCA
GATAGCAGCT GGAGAGGAAG TCTCAAAGTG CCCTACAATG TTGGACCTGG CTTTACTGGA
AACTTTTCTA CACAAAAAGT CAAGATGCAC ATCCACTCTA CCAATGAAGT GACAAGAATT
TACAATGTGA TAGGTACTCT CAGAGGAGCA GTGGAACCAG ACAGATATGT CATTCTGGGA
GGTCACCGGG ACTCATGGGT GTTTGGTGGT ATTGACCCTC AGAGTGGAGC AGCTGTTGTT
CATGAAATTG TGAGGAGCTT TGGAACACTG AAAAAGGAAG GGTGGAGACC TAGAAGAACA
ATTTTGTTTG CAAGCTGGGA TGCAGAAGAA TTTGGTCTTC TTGGTTCTAC TGAGTGGGCA
GAGGAGAATT CAAGACTCCT TCAAGAGCGT GGCGTGGCTT ATATTAATGC TGACTCATCT
ATAGAAGGAA ACTACACTCT GAGAGTTGAT TGTACACCGC TGATGTACAG CTTGGTACAC
AACCTAACAA AAGAGCTGAA AAGCCCTGAT GAAGGCTTTG AAGGCAAATC TCTTTATGAA
AGTTGGACTA AAAAAAGTCC TTCCCCAGAG TTCAGTGGCA TGCCCAGGAT AAGCAAATTG
GGATCTGGAA ATGATTTTGA GGTGTTCTTC CAACGACTTG GAATTGCTTC AGGCAGAGCA
CGGTATACTA AAAATTGGGA AACAAACAAA TTCAGCGGCT ATCCACTGTA TCACAGTGTC
TATGAAACAT ATGAGTTGGT GGAAAAGTTT TATGATCCAA TGTTTAAATA TCACCTCACT
GTGGCCCAGG TTCGAGGAGG GATGGTGTTT GAGCTAGCCA ATTCCATAGT GCTCCCTTTT
GATTGTCGAG ATTATGCTGT AGTTTTAAGA AAGTATGCTG ACAAAATCTA CAGTATTTCT
ATGAAACATC CACAGGAAAT GAAGACATAC AGTGTATCAT TTGATTCACT TTTTTCTGCA
GTAAAGAATT TTACAGAAAT TGCTTCCAAG TTCAGTGAGA GACTCCAGGA CTTTGACAAA
AGCAAGCATG TCATCTATGC TCCAAGCAGC CACAACAAGT ATGCAGGGGA GTCATTCCCA
GGAATTTATG ATGCTCTGTT TGATATTGAA AGCAAAGTGG ACCCTTCCAA GGCCTGGGGA
GAAGTGAAGA GACAGATTTA TGTTGCAGCC TTCACAGTGC AGGCAGCTGC AGAGACTTTG
AGTGAAGTAG CCTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu16871
Accession Version NM_001193473.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1329bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product glutamate carboxypeptidase 2 isoform 5
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from M99487.1 and AK295368.1. Summary: This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. Alternative splicing gives rise to multiple transcript variants encoding several different isoforms. [provided by RefSeq, Jul 2010]. Transcript Variant: This variant (5) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (5) is shorter at the N-terminus compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK295368.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
ATGGGTGGCT CAGCACCACC AGATAGCAGC TGGAGAGGAA GTCTCAAAGT GCCCTACAAT 
GTTGGACCTG GCTTTACTGG AAACTTTTCT ACACAAAAAG TCAAGATGCA CATCCACTCT
ACCAATGAAG TGACAAGAAT TTACAATGTG ATAGGTACTC TCAGAGGAGC AGTGGAACCA
GACAGATATG TCATTCTGGG AGGTCACCGG GACTCATGGG TGTTTGGTGG TATTGACCCT
CAGAGTGGAG CAGCTGTTGT TCATGAAATT GTGAGGAGCT TTGGAACACT GAAAAAGGAA
GGGTGGAGAC CTAGAAGAAC AATTTTGTTT GCAAGCTGGG ATGCAGAAGA ATTTGGTCTT
CTTGGTTCTA CTGAGTGGGC AGAGGAGAAT TCAAGACTCC TTCAAGAGCG TGGCGTGGCT
TATATTAATG CTGACTCATC TATAGAAGGA AACTACACTC TGAGAGTTGA TTGTACACCG
CTGATGTACA GCTTGGTACA CAACCTAACA AAAGAGCTGA AAAGCCCTGA TGAAGGCTTT
GAAGGCAAAT CTCTTTATGA AAGTTGGACT AAAAAAAGTC CTTCCCCAGA GTTCAGTGGC
ATGCCCAGGA TAAGCAAATT GGGATCTGGA AATGATTTTG AGGTGTTCTT CCAACGACTT
GGAATTGCTT CAGGCAGAGC ACGGTATACT AAAAATTGGG AAACAAACAA ATTCAGCGGC
TATCCACTGT ATCACAGTGT CTATGAAACA TATGAGTTGG TGGAAAAGTT TTATGATCCA
ATGTTTAAAT ATCACCTCAC TGTGGCCCAG GTTCGAGGAG GGATGGTGTT TGAGCTAGCC
AATTCCATAG TGCTCCCTTT TGATTGTCGA GATTATGCTG TAGTTTTAAG AAAGTATGCT
GACAAAATCT ACAGTATTTC TATGAAACAT CCACAGGAAA TGAAGACATA CAGTGTATCA
TTTGATTCAC TTTTTTCTGC AGTAAAGAAT TTTACAGAAA TTGCTTCCAA GTTCAGTGAG
AGACTCCAGG ACTTTGACAA AAGCAACCCA ATAGTATTAA GAATGATGAA TGATCAACTC
ATGTTTCTGG AAAGAGCATT TATTGATCCA TTAGGGTTAC CAGACAGGCC TTTTTATAGG
CATGTCATCT ATGCTCCAAG CAGCCACAAC AAGTATGCAG GGGAGTCATT CCCAGGAATT
TATGATGCTC TGTTTGATAT TGAAAGCAAA GTGGACCCTT CCAAGGCCTG GGGAGAAGTG
AAGAGACAGA TTTATGTTGC AGCCTTCACA GTGCAGGCAG CTGCAGAGAC TTTGAGTGAA
GTAGCCTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqNP_001180402.1
CDS812..2140
Misc Feature(1)710..712(+)
Misc Feature(2)812..925(+)
Misc Feature(3)929..1672(+)
Misc Feature(4)989..1219(+)
Misc Feature(5)1016..1546(+)
Misc Feature(6)1016..1546(+)
Misc Feature(7)1763..2134(+)
Exon (1)1..379
Gene:FOLH1
Gene Synonym:
Exon (2)380..485
Gene:FOLH1
Gene Synonym:
Exon (3)486..587
Gene:FOLH1
Gene Synonym:
Exon (4)588..713
Gene:FOLH1
Gene Synonym:
Exon (5)714..807
Gene:FOLH1
Gene Synonym:
Exon (6)808..906
Gene:FOLH1
Gene Synonym:
Exon (7)907..992
Gene:FOLH1
Gene Synonym:
Exon (8)993..1112
Gene:FOLH1
Gene Synonym:
Exon (9)1113..1195
Gene:FOLH1
Gene Synonym:
Exon (10)1196..1259
Gene:FOLH1
Gene Synonym:
Exon (11)1260..1327
Gene:FOLH1
Gene Synonym:
Exon (12)1328..1419
Gene:FOLH1
Gene Synonym:
Exon (13)1420..1510
Gene:FOLH1
Gene Synonym:
Exon (14)1511..1775
Gene:FOLH1
Gene Synonym:
Exon (15)1776..1857
Gene:FOLH1
Gene Synonym:
Exon (16)1858..1950
Gene:FOLH1
Gene Synonym:
Exon (17)1951..2261
Gene:FOLH1
Gene Synonym:
Translation
Position Chain Variation Link
20 20 c, t dbSNP:541641740
47 47 c, t dbSNP:779026088
80 80 g, t dbSNP:73473180
113 113 a, g dbSNP:761918085
135 135 c, g dbSNP:556080861
198 198 a, t dbSNP:539348188
212 212 a, g dbSNP:776584552
217 217 c, t dbSNP:368802471
226 226 a, c dbSNP:768289590
233 233 a, c dbSNP:747291464
236 236 a, g dbSNP:780112854
241 241 a, g dbSNP:772239186
244 244 a, g, t dbSNP:779460031
246 246 c, t dbSNP:570144568
247 247 g, t dbSNP:754283916
248 248 c, t dbSNP:553713122
253 253 a, c, t dbSNP:751275631
254 254 c, g dbSNP:765934623
258 258 a, c, g dbSNP:533521065
259 259 a, g dbSNP:764785511
261 261 a, g dbSNP:761867374
271 271 c, t dbSNP:181802264
273 273 c, t dbSNP:768540456
274 274 -, ctt dbSNP:369788403
275 275 -, ttc dbSNP:200069827
279 279 c, g, t dbSNP:775836030
282 282 a, g dbSNP:772177112
286 286 a, g dbSNP:746021500
289 289 c, t dbSNP:778975625
290 290 c, t dbSNP:770948188
292 292 a, g dbSNP:749825495
299 299 c, t dbSNP:778111409
309 309 c, g dbSNP:756559634
315 315 a, g dbSNP:753000475
317 317 a, g dbSNP:781554951
323 323 g, t dbSNP:547930923
331 331 g, t dbSNP:750049863
335 335 a, c dbSNP:764873716
347 347 c, g dbSNP:756800218
349 349 a, g dbSNP:753879892
351 351 g, t dbSNP:763921289
353 353 a, g dbSNP:760582412
361 361 c, g dbSNP:775151051
366 366 a, c dbSNP:767282960
378 378 a, c dbSNP:759774909
381 381 a, g dbSNP:777448978
396 396 c, t dbSNP:146574307
398 398 c, g dbSNP:747681322
406 406 g, t dbSNP:780613989
412 412 a, c dbSNP:754923320
413 413 a, c dbSNP:778887610
429 429 c, t dbSNP:751451081
430 430 a, g dbSNP:779857228
453 453 a, g dbSNP:372054306
468 468 c, t dbSNP:750664447
471 471 a, c dbSNP:368001797
482 482 c, t dbSNP:765488104
484 484 c, t dbSNP:202676
488 488 g, t dbSNP:780410301
493 493 a, g dbSNP:144409953
494 494 a, c dbSNP:375439459
497 497 a, g dbSNP:199532174
499 499 c, t dbSNP:765524382
501 501 c, t dbSNP:760347053
515 515 a, t dbSNP:752256226
517 517 c, t dbSNP:371189186
518 518 -, a dbSNP:34540261
521 521 a, g dbSNP:767098710
525 525 c, t dbSNP:758949926
527 527 c, t dbSNP:534437382
534 534 a, g dbSNP:770988853
538 538 c, t dbSNP:137879711
539 539 a, g, t dbSNP:377754089
540 540 a, g dbSNP:748441657
543 543 a, g dbSNP:781246950
552 552 c, g dbSNP:138510346
554 554 -, ga dbSNP:768935536
555 555 -, ttc dbSNP:749756788
558 558 a, g dbSNP:747052707
573 573 a, c dbSNP:765937451
577 577 a, g dbSNP:267602926
585 585 a, g dbSNP:780110705
590 590 c, t dbSNP:79155991
591 591 a, g, t dbSNP:778134535
596 596 a, g dbSNP:754599970
611 611 c, t dbSNP:75655145
615 615 c, t dbSNP:377095633
616 616 a, g dbSNP:757958518
620 620 c, t dbSNP:750442389
625 625 a, c dbSNP:765257997
638 638 g, t dbSNP:761741517
639 639 a, g dbSNP:776299190
642 642 c, t dbSNP:75940285
643 643 a, g dbSNP:138028811
646 646 a, g dbSNP:775663569
652 652 a, g dbSNP:772191107
676 676 c, t dbSNP:745938739
686 686 a, g dbSNP:548891620
689 689 c, t dbSNP:774906963
690 690 a, g dbSNP:397834560
691 691 a, c, g dbSNP:749746330
696 696 a, g dbSNP:778021759
702 702 a, c dbSNP:756469525
708 708 a, c dbSNP:746707926
718 718 c, t dbSNP:76509850
728 728 a, c, t dbSNP:772709942
729 729 a, g dbSNP:116795343
732 732 a, g dbSNP:747651254
737 737 a, g dbSNP:776050215
746 746 a, g dbSNP:768593308
747 747 g, t dbSNP:199756411
750 750 g, t dbSNP:779925727
752 752 c, t dbSNP:758094309
758 758 a, g dbSNP:746148342
764 764 c, t dbSNP:779267530
776 776 a, g dbSNP:199782232
780 780 a, g dbSNP:753976336
781 781 a, g dbSNP:370918056
786 786 a, g dbSNP:544801161
787 787 c, t dbSNP:143206032
788 788 a, g dbSNP:753104799
791 791 a, g dbSNP:767966355
799 799 c, g, t dbSNP:750141457
802 802 c, t dbSNP:764872934
805 805 a, g dbSNP:761397113
811 811 a, c dbSNP:149084901
815 815 a, g dbSNP:781273827
822 822 c, t dbSNP:755461606
825 825 c, t dbSNP:146472302
826 826 a, t dbSNP:780433799
833 833 c, g dbSNP:758736399
834 834 a, g dbSNP:753543878
848 848 a, g dbSNP:143707827
863 863 c, t dbSNP:2851557
865 865 c, g, t dbSNP:149023247
867 867 a, c, g dbSNP:767008939
887 887 a, g dbSNP:200257783
889 889 c, t dbSNP:774399823
897 897 c, t dbSNP:766325948
901 901 c, t dbSNP:144950409
911 911 c, g dbSNP:761981128
918 918 a, t dbSNP:776887467
921 921 a, g dbSNP:768777213
924 924 c, t dbSNP:749809918
930 930 c, t dbSNP:747084668
940 940 a, g dbSNP:775479716
943 943 a, g dbSNP:555590356
946 946 a, g dbSNP:202716
960 960 g, t dbSNP:746340486
965 965 a, g dbSNP:376770386
973 973 c, t dbSNP:771300656
975 975 g, t dbSNP:747804638
978 978 g, t dbSNP:780980012
980 980 a, g dbSNP:140577100
981 981 a, c dbSNP:751121376
982 982 a, g dbSNP:375313419
983 983 a, g dbSNP:758439576
995 995 a, g dbSNP:757072600
997 997 a, g dbSNP:556893770
1000 1000 c, t dbSNP:146822849
1002 1002 a, c, t dbSNP:752888961
1003 1003 c, g, t dbSNP:759648885
1006 1006 c, t dbSNP:774787551
1007 1007 c, g dbSNP:539478487
1011 1011 a, g dbSNP:771474698
1019 1019 c, t dbSNP:763312906
1020 1020 a, g dbSNP:199982130
1030 1030 a, g dbSNP:770250830
1033 1033 a, g dbSNP:201886725
1080 1080 c, t dbSNP:746707807
1084 1084 a, g dbSNP:775268651
1088 1088 a, g dbSNP:771545439
1094 1094 c, g dbSNP:745384542
1100 1100 a, c dbSNP:778225999
1104 1104 a, t dbSNP:757243757
1108 1108 c, g dbSNP:749187256
1111 1111 -, t dbSNP:777223627
1114 1114 a, g, t dbSNP:548160675
1149 1149 a, g dbSNP:751037727
1152 1152 a, g dbSNP:765839849
1155 1155 c, t dbSNP:762349547
1156 1156 a, c dbSNP:149765617
1171 1171 c, t dbSNP:764328677
1176 1176 a, g dbSNP:370887055
1196 1196 a, g dbSNP:772733825
1198 1198 a, g dbSNP:571898670
1208 1208 c, t dbSNP:770157136
1210 1210 a, c dbSNP:761785897
1220 1220 c, t dbSNP:776416420
1221 1221 a, g dbSNP:768558882
1226 1226 a, g dbSNP:375484734
1233 1233 a, g dbSNP:779839853
1246 1246 c, t dbSNP:772444946
1247 1247 g, t dbSNP:746046584
1260 1260 a, g dbSNP:764782539
1264 1264 c, g, t dbSNP:201724751
1282 1282 c, t dbSNP:763952088
1287 1287 c, t dbSNP:760611361
1290 1290 c, t dbSNP:139716793
1291 1291 a, g, t dbSNP:370741711
1300 1300 c, t dbSNP:774702332
1304 1304 a, t dbSNP:771203092
1310 1310 c, t dbSNP:61886492
1311 1311 -, a dbSNP:750419915
1315 1315 c, t dbSNP:777855460
1342 1342 g, t dbSNP:769888591
1343 1343 g, t dbSNP:748659279
1345 1345 a, t dbSNP:781660664
1355 1355 a, g dbSNP:755407695
1356 1356 a, g dbSNP:142952497
1359 1359 a, g dbSNP:780347923
1369 1369 c, t dbSNP:756890455
1379 1379 a, g, t dbSNP:763560048
1382 1382 a, g dbSNP:755638709
1383 1383 a, g dbSNP:752750462
1388 1388 -, a dbSNP:764290022
1388 1388 a, c, t dbSNP:533663504
1389 1389 -, aac dbSNP:763365445
1389 1389 a, g dbSNP:751426248
1433 1433 a, g dbSNP:140204056
1445 1445 a, g dbSNP:267602925
1466 1466 a, c, t dbSNP:372239425
1468 1468 a, g dbSNP:780894233
1480 1480 c, t dbSNP:754516463
1488 1488 g, t dbSNP:751608388
1493 1493 c, t dbSNP:368939818
1494 1494 c, g dbSNP:758208664
1495 1495 a, g dbSNP:750250735
1496 1496 c, t dbSNP:764896694
1505 1505 a, g dbSNP:757509976
1507 1507 c, t dbSNP:754036827
1510 1510 a, g dbSNP:764214736
1511 1511 a, g dbSNP:766910423
1528 1528 c, t dbSNP:182388588
1529 1529 a, g, t dbSNP:199709866
1534 1534 c, t dbSNP:746598910
1536 1536 c, g dbSNP:775101916
1561 1561 a, t dbSNP:771459907
1569 1569 c, t dbSNP:745876378
1570 1570 a, g dbSNP:778816102
1571 1571 a, g dbSNP:757118184
1579 1579 a, g dbSNP:553564027
1585 1585 a, t dbSNP:777496962
1588 1588 c, t dbSNP:756390079
1592 1592 a, g dbSNP:752832734
1618 1618 c, t dbSNP:781385635
1619 1619 c, t dbSNP:755001634
1645 1645 a, g dbSNP:752182257
1648 1648 a, g dbSNP:767004193
1652 1652 a, g dbSNP:763502164
1662 1662 g, t dbSNP:750845012
1668 1668 c, t dbSNP:765662116
1679 1679 c, t dbSNP:760423374
1680 1680 a, g dbSNP:774991864
1682 1682 a, g dbSNP:771677058
1687 1687 c, t dbSNP:758972352
1690 1690 c, t dbSNP:773794097
1692 1692 c, t dbSNP:567800489
1708 1708 c, t dbSNP:147500653
1709 1709 a, g dbSNP:777584883
1722 1722 a, g dbSNP:769456909
1725 1725 a, g dbSNP:748464478
1726 1726 c, t dbSNP:781269388
1733 1733 a, g dbSNP:755164162
1734 1734 g, t dbSNP:751708654
1745 1745 a, c dbSNP:143235150
1758 1758 a, c dbSNP:759009835
1763 1763 a, g dbSNP:750940557
1764 1764 a, g dbSNP:375836358
1770 1770 c, t dbSNP:762079463
1771 1771 a, c dbSNP:754163774
1774 1774 c, t dbSNP:767089077
1780 1780 a, g dbSNP:137991256
1798 1798 a, g dbSNP:757724515
1799 1799 a, c dbSNP:754177008
1801 1801 c, t dbSNP:535155505
1808 1808 a, g dbSNP:764479615
1814 1814 c, g dbSNP:566020349
1818 1818 a, c dbSNP:546821955
1828 1828 c, t dbSNP:199517010
1831 1831 a, g dbSNP:762448723
1846 1846 c, t dbSNP:144512496
1849 1849 c, t dbSNP:765103565
1860 1860 c, t dbSNP:375948834
1862 1862 a, g dbSNP:757992698
1873 1873 a, g dbSNP:372016808
1882 1882 c, t dbSNP:764768918
1885 1885 c, t dbSNP:761703243
1891 1891 c, g dbSNP:372600008
1899 1899 c, t dbSNP:764045804
1901 1901 g, t dbSNP:760548601
1925 1925 a, g dbSNP:371048605
1927 1927 a, g dbSNP:772445044
1933 1933 a, g dbSNP:746064073
1939 1939 a, g dbSNP:373131146
1940 1940 c, t dbSNP:771023021
1947 1947 a, g dbSNP:749820405
1948 1948 c, t dbSNP:778342843
1967 1967 a, c dbSNP:200462865
1974 1974 a, g dbSNP:149242168
1977 1977 a, g dbSNP:112972107
1978 1978 a, c dbSNP:770985396
1981 1981 c, t dbSNP:763102212
1988 1988 g, t dbSNP:368721018
1994 1994 a, g dbSNP:770312515
2021 2021 c, g dbSNP:748619991
2030 2030 a, g dbSNP:781582032
2032 2032 c, t dbSNP:201855858
2037 2037 a, c, g dbSNP:560179737
2038 2038 a, c dbSNP:150088430
2039 2039 a, g dbSNP:753409936
2056 2056 a, g dbSNP:777377989
2063 2063 a, g dbSNP:756160678
2068 2068 a, t dbSNP:1803128
2085 2085 a, c dbSNP:1803127
2086 2086 c, t dbSNP:752660381
2094 2094 c, t dbSNP:767480479
2097 2097 a, t dbSNP:140860006
2100 2100 c, t dbSNP:759372952
2103 2103 g, t dbSNP:759943723
2115 2115 c, t dbSNP:751249618
2130 2130 a, g dbSNP:550087931
2137 2137 c, g dbSNP:766640846
2142 2142 a, g dbSNP:763040665
2145 2145 a, t dbSNP:773315602
2148 2148 c, t dbSNP:595139
2160 2160 c, t dbSNP:374114868
2161 2161 a, g dbSNP:777116852
2167 2167 a, c dbSNP:768974420
2175 2175 c, t dbSNP:371921219
2204 2204 a, g dbSNP:556881101
2218 2218 c, t dbSNP:186975068

Target ORF information:

RefSeq Version NM_001193473
Organism Homo sapiens (human)
Definition Homo sapiens folate hydrolase (prostate-specific membrane antigen) 1 (FOLH1), transcript variant 5, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001193473

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
ATGGGTGGCT CAGCACCACC AGATAGCAGC TGGAGAGGAA GTCTCAAAGT GCCCTACAAT 
GTTGGACCTG GCTTTACTGG AAACTTTTCT ACACAAAAAG TCAAGATGCA CATCCACTCT
ACCAATGAAG TGACAAGAAT TTACAATGTG ATAGGTACTC TCAGAGGAGC AGTGGAACCA
GACAGATATG TCATTCTGGG AGGTCACCGG GACTCATGGG TGTTTGGTGG TATTGACCCT
CAGAGTGGAG CAGCTGTTGT TCATGAAATT GTGAGGAGCT TTGGAACACT GAAAAAGGAA
GGGTGGAGAC CTAGAAGAAC AATTTTGTTT GCAAGCTGGG ATGCAGAAGA ATTTGGTCTT
CTTGGTTCTA CTGAGTGGGC AGAGGAGAAT TCAAGACTCC TTCAAGAGCG TGGCGTGGCT
TATATTAATG CTGACTCATC TATAGAAGGA AACTACACTC TGAGAGTTGA TTGTACACCG
CTGATGTACA GCTTGGTACA CAACCTAACA AAAGAGCTGA AAAGCCCTGA TGAAGGCTTT
GAAGGCAAAT CTCTTTATGA AAGTTGGACT AAAAAAAGTC CTTCCCCAGA GTTCAGTGGC
ATGCCCAGGA TAAGCAAATT GGGATCTGGA AATGATTTTG AGGTGTTCTT CCAACGACTT
GGAATTGCTT CAGGCAGAGC ACGGTATACT AAAAATTGGG AAACAAACAA ATTCAGCGGC
TATCCACTGT ATCACAGTGT CTATGAAACA TATGAGTTGG TGGAAAAGTT TTATGATCCA
ATGTTTAAAT ATCACCTCAC TGTGGCCCAG GTTCGAGGAG GGATGGTGTT TGAGCTAGCC
AATTCCATAG TGCTCCCTTT TGATTGTCGA GATTATGCTG TAGTTTTAAG AAAGTATGCT
GACAAAATCT ACAGTATTTC TATGAAACAT CCACAGGAAA TGAAGACATA CAGTGTATCA
TTTGATTCAC TTTTTTCTGC AGTAAAGAAT TTTACAGAAA TTGCTTCCAA GTTCAGTGAG
AGACTCCAGG ACTTTGACAA AAGCAACCCA ATAGTATTAA GAATGATGAA TGATCAACTC
ATGTTTCTGG AAAGAGCATT TATTGATCCA TTAGGGTTAC CAGACAGGCC TTTTTATAGG
CATGTCATCT ATGCTCCAAG CAGCCACAAC AAGTATGCAG GGGAGTCATT CCCAGGAATT
TATGATGCTC TGTTTGATAT TGAAAGCAAA GTGGACCCTT CCAAGGCCTG GGGAGAAGTG
AAGAGACAGA TTTATGTTGC AGCCTTCACA GTGCAGGCAG CTGCAGAGAC TTTGAGTGAA
GTAGCCTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu16608
Accession Version NM_001014986.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2160bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product glutamate carboxypeptidase 2 isoform 2
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from M99487.1 and BC025672.1. Summary: This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. Alternative splicing gives rise to multiple transcript variants encoding several different isoforms. [provided by RefSeq, Jul 2010]. Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC025672.1, DQ088979.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
ATGTGGAATC TCCTTCACGA AACCGACTCG GCTGTGGCCA CCGCGCGCCG CCCGCGCTGG 
CTGTGCGCTG GGGCGCTGGT GCTGGCGGGT GGCTTCTTTC TCCTCGGCTT CCTCTTCGGG
TGGTTTATAA AATCCTCCAA TGAAGCTACT AACATTACTC CAAAGCATAA TATGAAAGCA
TTTTTGGATG AATTGAAAGC TGAGAACATC AAGAAGTTCT TATATAATTT TACACAGATA
CCACATTTAG CAGGAACAGA ACAAAACTTT CAGCTTGCAA AGCAAATTCA ATCCCAGTGG
AAAGAATTTG GCCTGGATTC TGTTGAGCTA GCACATTATG ATGTCCTGTT GTCCTACCCA
AATAAGACTC ATCCCAACTA CATCTCAATA ATTAATGAAG ATGGAAATGA GATTTTCAAC
ACATCATTAT TTGAACCACC TCCTCCAGGA TATGAAAATG TTTCGGATAT TGTACCACCT
TTCAGTGCTT TCTCTCCTCA AGGAATGCCA GAGGGCGATC TAGTGTATGT TAACTATGCA
CGAACTGAAG ACTTCTTTAA ATTGGAACGG GACATGAAAA TCAATTGCTC TGGGAAAATT
GTAATTGCCA GATATGGGAA AGTTTTCAGA GGAAATAAGG TTAAAAATGC CCAGCTGGCA
GGGGCCAAAG GAGTCATTCT CTACTCCGAC CCTGCTGACT ACTTTGCTCC TGGGGTGAAG
TCCTATCCAG ATGGTTGGAA TCTTCCTGGA GGTGGTGTCC AGCGTGGAAA TATCCTAAAT
CTGAATGGTG CAGGAGACCC TCTCACACCA GGTTACCCAG CAAATGAATA TGCTTATAGG
CGTGGAATTG CAGAGGCTGT TGGTCTTCCA AGTATTCCTG TTCATCCAAT TGGATACTAT
GATGCACAGA AGCTCCTAGA AAAAATGGGT GGCTCAGCAC CACCAGATAG CAGCTGGAGA
GGAAGTCTCA AAGTGCCCTA CAATGTTGGA CCTGGCTTTA CTGGAAACTT TTCTACACAA
AAAGTCAAGA TGCACATCCA CTCTACCAAT GAAGTGACAA GAATTTACAA TGTGATAGGT
ACTCTCAGAG GAGCAGTGGA ACCAGACAGA TATGTCATTC TGGGAGGTCA CCGGGACTCA
TGGGTGTTTG GTGGTATTGA CCCTCAGAGT GGAGCAGCTG TTGTTCATGA AATTGTGAGG
AGCTTTGGAA CACTGAAAAA GGAAGGGTGG AGACCTAGAA GAACAATTTT GTTTGCAAGC
TGGGATGCAG AAGAATTTGG TCTTCTTGGT TCTACTGAGT GGGCAGAGGA GAATTCAAGA
CTCCTTCAAG AGCGTGGCGT GGCTTATATT AATGCTGACT CATCTATAGA AGGAAACTAC
ACTCTGAGAG TTGATTGTAC ACCGCTGATG TACAGCTTGG TACACAACCT AACAAAAGAG
CTGAAAAGCC CTGATGAAGG CTTTGAAGGC AAATCTCTTT ATGAAAGTTG GACTAAAAAA
AGTCCTTCCC CAGAGTTCAG TGGCATGCCC AGGATAAGCA AATTGGGATC TGGAAATGAT
TTTGAGGTGT TCTTCCAACG ACTTGGAATT GCTTCAGGCA GAGCACGGTA TACTAAAAAT
TGGGAAACAA ACAAATTCAG CGGCTATCCA CTGTATCACA GTGTCTATGA AACATATGAG
TTGGTGGAAA AGTTTTATGA TCCAATGTTT AAATATCACC TCACTGTGGC CCAGGTTCGA
GGAGGGATGG TGTTTGAGCT AGCCAATTCC ATAGTGCTCC CTTTTGATTG TCGAGATTAT
GCTGTAGTTT TAAGAAAGTA TGCTGACAAA ATCTACAGTA TTTCTATGAA ACATCCACAG
GAAATGAAGA CATACAGTGT ATCATTTGAT TCACTTTTTT CTGCAGTAAA GAATTTTACA
GAAATTGCTT CCAAGTTCAG TGAGAGACTC CAGGACTTTG ACAAAAGCAA GCATGTCATC
TATGCTCCAA GCAGCCACAA CAAGTATGCA GGGGAGTCAT TCCCAGGAAT TTATGATGCT
CTGTTTGATA TTGAAAGCAA AGTGGACCCT TCCAAGGCCT GGGGAGAAGT GAAGAGACAG
ATTTATGTTG CAGCCTTCAC AGTGCAGGCA GCTGCAGAGA CTTTGAGTGA AGTAGCCTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqNP_001014986.1
CDS262..2421
Misc Feature(1)166..168(+)
Misc Feature(2)412..414(+)
Misc Feature(3)433..>603(+)
Misc Feature(4)487..489(+)
Misc Feature(5)619..1299(+)
Misc Feature(6)622..624(+)
Misc Feature(7)679..681(+)
Misc Feature(8)718..720(+)
Misc Feature(9)751..1068(+)
Misc Feature(10)844..846(+)
Misc Feature(11)889..1032(+)
Misc Feature(12)1075..1092(+)
Misc Feature(13)1267..1269(+)
Misc Feature(14)1303..2046(+)
Misc Feature(15)1363..1593(+)
Misc Feature(16)1390..1920(+)
Misc Feature(17)1390..1920(+)
Misc Feature(18)1636..1638(+)
Misc Feature(19)1687..1689(+)
Misc Feature(20)2137..2415(+)
Misc Feature(21)2173..2175(+)
Exon (1)1..379
Gene:FOLH1
Gene Synonym:
Exon (2)380..485
Gene:FOLH1
Gene Synonym:
Exon (3)486..672
Gene:FOLH1
Gene Synonym:
Exon (4)673..774
Gene:FOLH1
Gene Synonym:
Exon (5)775..900
Gene:FOLH1
Gene Synonym:
Exon (6)901..1087
Gene:FOLH1
Gene Synonym:
Exon (7)1088..1181
Gene:FOLH1
Gene Synonym:
Exon (8)1182..1280
Gene:FOLH1
Gene Synonym:
Exon (9)1281..1366
Gene:FOLH1
Gene Synonym:
Exon (10)1367..1486
Gene:FOLH1
Gene Synonym:
Exon (11)1487..1569
Gene:FOLH1
Gene Synonym:
Exon (12)1570..1633
Gene:FOLH1
Gene Synonym:
Exon (13)1634..1701
Gene:FOLH1
Gene Synonym:
Exon (14)1702..1793
Gene:FOLH1
Gene Synonym:
Exon (15)1794..1884
Gene:FOLH1
Gene Synonym:
Exon (16)1885..2149
Gene:FOLH1
Gene Synonym:
Exon (17)2150..2231
Gene:FOLH1
Gene Synonym:
Exon (18)2232..2542
Gene:FOLH1
Gene Synonym:
Translation
Position Chain Variation Link
20 20 c, t dbSNP:541641740
47 47 c, t dbSNP:779026088
80 80 g, t dbSNP:73473180
113 113 a, g dbSNP:761918085
135 135 c, g dbSNP:556080861
198 198 a, t dbSNP:539348188
212 212 a, g dbSNP:776584552
217 217 c, t dbSNP:368802471
226 226 a, c dbSNP:768289590
233 233 a, c dbSNP:747291464
236 236 a, g dbSNP:780112854
241 241 a, g dbSNP:772239186
244 244 a, g, t dbSNP:779460031
246 246 c, t dbSNP:570144568
247 247 g, t dbSNP:754283916
248 248 c, t dbSNP:553713122
253 253 a, c, t dbSNP:751275631
254 254 c, g dbSNP:765934623
258 258 a, c, g dbSNP:533521065
259 259 a, g dbSNP:764785511
261 261 a, g dbSNP:761867374
271 271 c, t dbSNP:181802264
273 273 c, t dbSNP:768540456