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CLDN14 claudin 14 [Homo sapiens (human)]

Gene Symbol CLDN14
Entrez Gene ID 23562
Full Name claudin 14
Synonyms DFNB29
General protein information
Preferred Names
claudin-14
Names
claudin-14
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

21

21q22.3

Summary Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. The encoded protein also binds specifically to the WW domain of Yes-associated protein. Defects in this gene are the cause of an autosomal recessive form of nonsyndromic sensorineural deafness. It is also reported that four synonymous variants in this gene are associated with kidney stones and reduced bone mineral density. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jun 2010]. lac of sum
Disorder MIM:

605608

Disorder Html: Deafness, autosomal recessive 29 (3)





The following CLDN14 gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CLDN14 gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu20415 NM_012130 Homo sapiens claudin 14 (CLDN14), transcript variant epsilon, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$188.3
$269
OHu20415 XM_011529519 PREDICTED: Homo sapiens claudin 14 (CLDN14), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$139.3
$199
OHu20415 NM_001146078 Homo sapiens claudin 14 (CLDN14), transcript variant gamma, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$188.3
$269
OHu20415 NM_001146077 Homo sapiens claudin 14 (CLDN14), transcript variant 3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$188.3
$269
OHu20415 NM_144492 Homo sapiens claudin 14 (CLDN14), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$188.3
$269
OHu20415 NM_001146079 Homo sapiens claudin 14 (CLDN14), transcript variant 5, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$188.3
$269

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu20415
Accession Version NM_012130.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 720bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 26-MAY-2014
Organism Homo sapiens (human)
Product claudin-14
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AY355349.1 and BC012126.1. On Jul 3, 2012 this sequence version replaced gi:21536295. Summary: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. The encoded protein also binds specifically to the WW domain of Yes-associated protein. Defects in this gene are the cause of an autosomal recessive form of nonsyndromic sensorineural deafness. It is also reported that four synonymous variants in this gene are associated with kidney stones and reduced bone mineral density. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jun 2010]. Transcript Variant: This variant (epsilon) differs in the 5' UTR compared to variant 1. All five variants encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC012126.1, BM911659.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
ATGGCCAGCA CGGCCGTGCA GCTTCTGGGC TTCCTGCTCA GCTTCCTGGG CATGGTGGGC 
ACGTTGATCA CCACCATCCT GCCGCACTGG CGGAGGACAG CGCACGTGGG CACCAACATC
CTCACGGCCG TGTCCTACCT GAAAGGGCTC TGGATGGAGT GTGTGTGGCA CAGCACAGGC
ATCTACCAGT GCCAGATCTA CCGATCCCTG CTGGCGCTGC CCCAAGACCT CCAGGCTGCC
CGCGCCCTCA TGGTCATCTC CTGCCTGCTC TCGGGCATAG CCTGCGCCTG CGCCGTCATC
GGGATGAAGT GCACGCGCTG CGCCAAGGGC ACACCCGCCA AGACCACCTT TGCCATCCTC
GGCGGCACCC TCTTCATCCT GGCCGGCCTC CTGTGCATGG TGGCCGTCTC CTGGACCACC
AACGACGTGG TGCAGAACTT CTACAACCCG CTGCTGCCCA GCGGCATGAA GTTTGAGATT
GGCCAGGCCC TGTACCTGGG CTTCATCTCC TCGTCCCTCT CGCTCATTGG TGGCACCCTG
CTTTGCCTGT CCTGCCAGGA CGAGGCACCC TACAGGCCCT ACCAGGCCCC GCCCAGGGCC
ACCACGACCA CTGCAAACAC CGCACCTGCC TACCAGCCAC CAGCTGCCTA CAAAGACAAT
CGGGCCCCCT CAGTGACCTC GGCCACGCAC AGCGGGTACA GGCTGAACGA CTACGTGTGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_036262.1
CDS157..876
Misc Feature(1)139..141(+)
Misc Feature(2)178..240(+)
Misc Feature(3)223..699(+)
Misc Feature(4)400..462(+)
Misc Feature(5)502..564(+)
Misc Feature(6)643..705(+)
Exon (1)1..75
Gene:CLDN14
Gene Synonym:
Exon (2)76..1231
Gene:CLDN14
Gene Synonym:
Translation
Position Chain Variation Link
22 22 c, t dbSNP:768883066
31 31 a, g dbSNP:760480583
35 35 c, g dbSNP:564915811
55 55 a, c dbSNP:545020329
69 69 c, t dbSNP:371272476
70 70 a, g dbSNP:376127472
81 81 c, t dbSNP:557122405
82 82 a, g, t dbSNP:537529014
99 99 c, t dbSNP:759652223
100 100 a, g dbSNP:188479887
104 104 g, t dbSNP:548165835
111 111 a, g dbSNP:779699092
120 120 a, g dbSNP:149049781
131 131 a, g dbSNP:758426367
132 132 c, g dbSNP:750364874
152 152 a, g dbSNP:368231049
166 166 a, g dbSNP:374578221
167 167 c, t dbSNP:113831133
168 168 a, g dbSNP:764358289
171 171 c, t dbSNP:387907416
172 172 a, g dbSNP:202117396
174 174 a, g dbSNP:387907417
184 184 c, g dbSNP:772295911
207 207 c, t dbSNP:150040476
208 208 a, g dbSNP:369883669
211 211 g, t dbSNP:769320772
216 216 c, t dbSNP:387907415
218 218 c, t dbSNP:532176130
219 219 a, g dbSNP:117560775
220 220 -, ttg dbSNP:762948927
223 223 a, c dbSNP:780834768
224 224 c, t dbSNP:768411939
228 228 c, t dbSNP:549639383
230 230 c, t dbSNP:779937857
238 238 c, t dbSNP:758081638
239 239 c, t dbSNP:727504989
240 240 a, g dbSNP:778927942
247 247 c, t dbSNP:757426764
257 257 a, c dbSNP:754032374
258 258 a, g dbSNP:146395322
261 261 c, t dbSNP:560763542
262 262 a, g, t dbSNP:142205038
265 265 a, g dbSNP:759850341
272 272 -, aca dbSNP:752639706
281 281 c, t dbSNP:533194857
282 282 a, g dbSNP:140177046
285 285 c, t dbSNP:150731625
286 286 a, g dbSNP:141139613
315 315 a, g dbSNP:768019537
318 318 c, t dbSNP:746698259
320 320 c, t dbSNP:752960573
323 323 -, gg dbSNP:765103185
323 323 a, g dbSNP:371100799
325 325 c, t dbSNP:745601274
327 327 c, t dbSNP:778842030
337 337 a, t dbSNP:757334760
341 341 a, g dbSNP:148223897
351 351 a, g dbSNP:777960789
351 351 -, g dbSNP:760769965
359 359 a, g dbSNP:756095919
364 364 c, g dbSNP:752992781
365 365 g, t dbSNP:767565332
367 367 c, t dbSNP:755346413
371 371 c, t dbSNP:573588226
372 372 a, g dbSNP:370315827
374 374 a, t dbSNP:763489263
379 379 c, t dbSNP:560052879
384 384 c, t dbSNP:763692550
390 390 c, g dbSNP:760039736
395 395 c, t dbSNP:775222236
397 397 c, t dbSNP:143628692
398 398 a, g dbSNP:368027306
399 399 c, t dbSNP:219779
409 409 g, t dbSNP:770829440
410 410 a, t dbSNP:74315437
416 416 c, g dbSNP:777529810
418 418 c, t dbSNP:756218341
423 423 g, t dbSNP:748115585
424 424 c, g dbSNP:781318012
429 429 a, g dbSNP:577393948
432 432 c, g dbSNP:751747842
433 433 a, t dbSNP:780444223
436 436 c, g dbSNP:758724049
441 441 c, t dbSNP:750946312
442 442 a, g dbSNP:765605373
443 443 c, t dbSNP:762368755
447 447 a, c, t dbSNP:767108790
448 448 a, g dbSNP:759313432
450 450 -, tgcgcc dbSNP:773126341
450 450 c, t dbSNP:374400022
451 451 a, g dbSNP:371106978
455 455 c, t dbSNP:557513586
456 456 c, t dbSNP:113350364
457 457 a, g dbSNP:74315438
470 470 c, t dbSNP:748110915
471 471 a, g dbSNP:781167430
472 472 c, t dbSNP:140257182
473 473 a, g dbSNP:747254086
477 477 c, t dbSNP:764548516
478 478 a, g dbSNP:377019596
479 479 c, t dbSNP:373823945
491 491 a, c, t dbSNP:555911451
492 492 c, g, t dbSNP:754350037
493 493 a, c, g dbSNP:138631461
503 503 a, c, t dbSNP:370342285
508 508 a, c, g dbSNP:377333347
517 517 a, g dbSNP:150201704
519 519 c, t dbSNP:763411863
520 520 a, g dbSNP:769599110
525 525 a, c, t dbSNP:727502938
531 531 c, t dbSNP:768728088
535 535 c, t dbSNP:747033624
540 540 c, t dbSNP:780095902
541 541 a, g dbSNP:772250957
543 543 c, t dbSNP:558404405
548 548 c, t dbSNP:373777126
553 553 a, g dbSNP:757597772
554 554 -, t dbSNP:786200885
562 562 a, g dbSNP:140918123
569 569 a, g dbSNP:151069240
570 570 a, g dbSNP:142846225
575 575 c, t dbSNP:754545220
578 578 a, c dbSNP:751170450
579 579 a, c, t dbSNP:758024791
580 580 a, g dbSNP:146755542
582 582 c, t dbSNP:140671150
583 583 a, c, g dbSNP:776564488
586 586 a, g dbSNP:764077250
600 600 c, t dbSNP:549938800
605 605 c, t dbSNP:775588286
606 606 a, g, t dbSNP:746102559
615 615 c, t dbSNP:774596862
618 618 c, t dbSNP:771208295
619 619 a, g dbSNP:749603296
627 627 a, g dbSNP:146860442
635 635 c, t dbSNP:756749130
644 644 c, t dbSNP:143797113
645 645 c, g dbSNP:779757519
651 651 c, t dbSNP:373672296
655 655 a, g dbSNP:377158611
668 668 a, c, t dbSNP:75617474
669 669 a, c, g dbSNP:756847536
677 677 c, t dbSNP:140196815
678 678 a, g dbSNP:763846537
679 679 c, t dbSNP:760657763
681 681 c, t dbSNP:373226526
682 682 a, g dbSNP:767528825
691 691 a, g dbSNP:759597838
695 695 c, t dbSNP:774446882
696 696 a, g dbSNP:369688436
699 699 g, t dbSNP:749515217
707 707 c, t dbSNP:773749542
712 712 c, g dbSNP:770259212
715 715 g, t dbSNP:375904468
717 717 a, c, t dbSNP:771486433
718 718 a, g dbSNP:745441972
724 724 c, t dbSNP:778283119
728 728 a, g dbSNP:755393537
736 736 c, t dbSNP:372105353
743 743 c, t dbSNP:200651246
744 744 a, c, g dbSNP:144371384
746 746 c, t dbSNP:374682296
747 747 a, g dbSNP:374840285
759 759 a, c dbSNP:760219487
761 761 c, t dbSNP:564851292
762 762 a, g dbSNP:763313658
770 770 c, t dbSNP:149671826
774 774 c, t dbSNP:184035890
777 777 c, t dbSNP:139437157
778 778 a, g dbSNP:371297575
780 780 a, c dbSNP:769272352
781 781 a, c dbSNP:747443576
789 789 c, t dbSNP:61745291
797 797 c, t dbSNP:770382134
802 802 g, t dbSNP:748973638
813 813 c, t dbSNP:143566360
817 817 a, c, g, t dbSNP:548981290
818 818 a, g dbSNP:752592093
819 819 a, g dbSNP:387907414
820 820 -, g dbSNP:761918152
820 820 a, g, t dbSNP:138008896
820 820 -, g dbSNP:772380452
821 821 c, t dbSNP:751427421
830 830 c, t dbSNP:766586533
837 837 a, g dbSNP:763085148
842 842 c, t dbSNP:750677498
843 843 a, g dbSNP:219780
846 846 c, t dbSNP:149733854
849 849 c, t dbSNP:554611270
850 850 a, g dbSNP:786204841
864 864 c, t dbSNP:774161015
865 865 a, g dbSNP:768382153
870 870 a, c dbSNP:761269316
871 871 a, g dbSNP:201218449
882 882 c, t dbSNP:770435259
886 886 c, g dbSNP:139628442
887 887 c, t dbSNP:772699208
898 898 c, t dbSNP:769498667
899 899 a, c dbSNP:747720793
906 906 g, t dbSNP:781087324
909 909 a, g dbSNP:754677688
911 911 a, g dbSNP:746997205
920 920 c, t dbSNP:780070024
923 923 c, t dbSNP:758566130
924 924 a, g dbSNP:199523516
926 926 a, c dbSNP:765378283
927 927 a, g dbSNP:114551506
942 942 a, g dbSNP:369966830
983 983 a, g dbSNP:112112443
1041 1041 a, g dbSNP:150553857
1051 1051 a, g dbSNP:565686905
1086 1086 a, g dbSNP:567389844
1090 1090 -, a dbSNP:547523762
1106 1106 c, t dbSNP:547541223
1110 1110 c, t dbSNP:527363387
1127 1127 a, t dbSNP:746123433
1145 1145 c, g dbSNP:571301747
1153 1153 c, t dbSNP:551351878
1173 1173 a, c, g dbSNP:532695308
1180 1180 c, g dbSNP:377710646
1210 1210 a, g dbSNP:142629054
1211 1211 a, c dbSNP:185515617
1222 1222 -, ggtttt dbSNP:370594336
1223 1223 g, t dbSNP:201508874

Target ORF information:

RefSeq Version NM_012130
Organism Homo sapiens (human)
Definition Homo sapiens claudin 14 (CLDN14), transcript variant epsilon, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_012130

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
ATGGCCAGCA CGGCCGTGCA GCTTCTGGGC TTCCTGCTCA GCTTCCTGGG CATGGTGGGC 
ACGTTGATCA CCACCATCCT GCCGCACTGG CGGAGGACAG CGCACGTGGG CACCAACATC
CTCACGGCCG TGTCCTACCT GAAAGGGCTC TGGATGGAGT GTGTGTGGCA CAGCACAGGC
ATCTACCAGT GCCAGATCTA CCGATCCCTG CTGGCGCTGC CCCAAGACCT CCAGGCTGCC
CGCGCCCTCA TGGTCATCTC CTGCCTGCTC TCGGGCATAG CCTGCGCCTG CGCCGTCATC
GGGATGAAGT GCACGCGCTG CGCCAAGGGC ACACCCGCCA AGACCACCTT TGCCATCCTC
GGCGGCACCC TCTTCATCCT GGCCGGCCTC CTGTGCATGG TGGCCGTCTC CTGGACCACC
AACGACGTGG TGCAGAACTT CTACAACCCG CTGCTGCCCA GCGGCATGAA GTTTGAGATT
GGCCAGGCCC TGTACCTGGG CTTCATCTCC TCGTCCCTCT CGCTCATTGG TGGCACCCTG
CTTTGCCTGT CCTGCCAGGA CGAGGCACCC TACAGGCCCT ACCAGGCCCC GCCCAGGGCC
ACCACGACCA CTGCAAACAC CGCACCTGCC TACCAGCCAC CAGCTGCCTA CAAAGACAAT
CGGGCCCCCT CAGTGACCTC GGCCACGCAC AGCGGGTACA GGCTGAACGA CTACGTGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu20415
Accession Version XM_011529519.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 720bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product claudin-14 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_011512.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
ATGGCCAGCA CGGCCGTGCA GCTTCTGGGC TTCCTGCTCA GCTTCCTGGG CATGGTGGGC 
ACGTTGATCA CCACCATCCT GCCGCACTGG CGGAGGACAG CGCACGTGGG CACCAACATC
CTCACGGCCG TGTCCTACCT GAAAGGGCTC TGGATGGAGT GTGTGTGGCA CAGCACAGGC
ATCTACCAGT GCCAGATCTA CCGATCCCTG CTGGCGCTGC CCCAAGACCT CCAGGCTGCC
CGCGCCCTCA TGGTCATCTC CTGCCTGCTC TCGGGCATAG CCTGCGCCTG CGCCGTCATC
GGGATGAAGT GCACGCGCTG CGCCAAGGGC ACACCCGCCA AGACCACCTT TGCCATCCTC
GGCGGCACCC TCTTCATCCT GGCCGGCCTC CTGTGCATGG TGGCCGTCTC CTGGACCACC
AACGACGTGG TGCAGAACTT CTACAACCCG CTGCTGCCCA GCGGCATGAA GTTTGAGATT
GGCCAGGCCC TGTACCTGGG CTTCATCTCC TCGTCCCTCT CGCTCATTGG TGGCACCCTG
CTTTGCCTGT CCTGCCAGGA CGAGGCACCC TACAGGCCCT ACCAGGCCCC GCCCAGGGCC
ACCACGACCA CTGCAAACAC CGCACCTGCC TACCAGCCAC CAGCTGCCTA CAAAGACAAT
CGGGCCCCCT CAGTGACCTC GGCCACGCAC AGCGGGTACA GGCTGAACGA CTACGTGTGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqXP_011527821.1
CDS400..1119
Misc Feature(1)466..942(+)
Translation
Position Chain Variation Link
2 2 a, g dbSNP:555635916
10 10 c, t dbSNP:764397437
22 22 a, g dbSNP:535955355
34 34 a, t dbSNP:370544366
44 44 c, g dbSNP:142602810
66 66 c, g dbSNP:756186626
84 84 c, t dbSNP:549418890
99 99 -, aa dbSNP:746828506
109 109 -, agtgg dbSNP:578028247
124 124 c, t dbSNP:529630606
126 126 c, t dbSNP:569686154
127 127 a, g dbSNP:371644221
139 139 a, g dbSNP:781713485
152 152 a, t dbSNP:543996003
153 153 -, g dbSNP:35228464
162 162 a, g dbSNP:757769148
168 168 a, g dbSNP:8133667
185 185 c, t dbSNP:543178465
186 186 a, g dbSNP:529450999
203 203 c, g dbSNP:776693720
250 250 c, t dbSNP:57668637
267 267 a, g dbSNP:769191161
280 280 a, c dbSNP:747570919
296 296 c, t dbSNP:184746529
299 299 -, tt dbSNP:59563067
324 324 c, t dbSNP:557122405
325 325 a, g, t dbSNP:537529014
342 342 c, t dbSNP:759652223
343 343 a, g dbSNP:188479887
347 347 g, t dbSNP:548165835
354 354 a, g dbSNP:779699092
363 363 a, g dbSNP:149049781
374 374 a, g dbSNP:758426367
375 375 c, g dbSNP:750364874
395 395 a, g dbSNP:368231049
409 409 a, g dbSNP:374578221
410 410 c, t dbSNP:113831133
411 411 a, g dbSNP:764358289
414 414 c, t dbSNP:387907416
415 415 a, g dbSNP:202117396
417 417 a, g dbSNP:387907417
427 427 c, g dbSNP:772295911
450 450 c, t dbSNP:150040476
451 451 a, g dbSNP:369883669
454 454 g, t dbSNP:769320772
459 459 c, t dbSNP:387907415
461 461 c, t dbSNP:532176130
462 462 a, g dbSNP:117560775
463 463 -, ttg dbSNP:762948927
466 466 a, c dbSNP:780834768
467 467 c, t dbSNP:768411939
471 471 c, t dbSNP:549639383
473 473 c, t dbSNP:779937857
481 481 c, t dbSNP:758081638
482 482 c, t dbSNP:727504989
483 483 a, g dbSNP:778927942
490 490 c, t dbSNP:757426764
500 500 a, c dbSNP:754032374
501 501 a, g dbSNP:146395322
504 504 c, t dbSNP:560763542
505 505 a, g, t dbSNP:142205038
508 508 a, g dbSNP:759850341
515 515 -, aca dbSNP:752639706
524 524 c, t dbSNP:533194857
525 525 a, g dbSNP:140177046
528 528 c, t dbSNP:150731625
529 529 a, g dbSNP:141139613
558 558 a, g dbSNP:768019537
561 561 c, t dbSNP:746698259
563 563 c, t dbSNP:752960573
566 566 -, gg dbSNP:765103185
566 566 a, g dbSNP:371100799
568 568 c, t dbSNP:745601274
570 570 c, t dbSNP:778842030
580 580 a, t dbSNP:757334760
584 584 a, g dbSNP:148223897
594 594 a, g dbSNP:777960789
594 594 -, g dbSNP:760769965
602 602 a, g dbSNP:756095919
607 607 c, g dbSNP:752992781
608 608 g, t dbSNP:767565332
610 610 c, t dbSNP:755346413
614 614 c, t dbSNP:573588226
615 615 a, g dbSNP:370315827
617 617 a, t dbSNP:763489263
622 622 c, t dbSNP:560052879
627 627 c, t dbSNP:763692550
633 633 c, g dbSNP:760039736
638 638 c, t dbSNP:775222236
640 640 c, t dbSNP:143628692
641 641 a, g dbSNP:368027306
642 642 c, t dbSNP:219779
652 652 g, t dbSNP:770829440
653 653 a, t dbSNP:74315437
659 659 c, g dbSNP:777529810
661 661 c, t dbSNP:756218341
666 666 g, t dbSNP:748115585
667 667 c, g dbSNP:781318012
672 672 a, g dbSNP:577393948
675 675 c, g dbSNP:751747842
676 676 a, t dbSNP:780444223
679 679 c, g dbSNP:758724049
684 684 c, t dbSNP:750946312
685 685 a, g dbSNP:765605373
686 686 c, t dbSNP:762368755
690 690 a, c, t dbSNP:767108790
691 691 a, g dbSNP:759313432
693 693 -, tgcgcc dbSNP:773126341
693 693 c, t dbSNP:374400022
694 694 a, g dbSNP:371106978
698 698 c, t dbSNP:557513586
699 699 c, t dbSNP:113350364
700 700 a, g dbSNP:74315438
713 713 c, t dbSNP:748110915
714 714 a, g dbSNP:781167430
715 715 c, t dbSNP:140257182
716 716 a, g dbSNP:747254086
720 720 c, t dbSNP:764548516
721 721 a, g dbSNP:377019596
722 722 c, t dbSNP:373823945
734 734 a, c, t dbSNP:555911451
735 735 c, g, t dbSNP:754350037
736 736 a, c, g dbSNP:138631461
746 746 a, c, t dbSNP:370342285
751 751 a, c, g dbSNP:377333347
760 760 a, g dbSNP:150201704
762 762 c, t dbSNP:763411863
763 763 a, g dbSNP:769599110
768 768 a, c, t dbSNP:727502938
774 774 c, t dbSNP:768728088
778 778 c, t dbSNP:747033624
783 783 c, t dbSNP:780095902
784 784 a, g dbSNP:772250957
786 786 c, t dbSNP:558404405
791 791 c, t dbSNP:373777126
796 796 a, g dbSNP:757597772
797 797 -, t dbSNP:786200885
805 805 a, g dbSNP:140918123
812 812 a, g dbSNP:151069240
813 813 a, g dbSNP:142846225
818 818 c, t dbSNP:754545220
821 821 a, c dbSNP:751170450
822 822 a, c, t dbSNP:758024791
823 823 a, g dbSNP:146755542
825 825 c, t dbSNP:140671150
826 826 a, c, g dbSNP:776564488
829 829 a, g dbSNP:764077250
843 843 c, t dbSNP:549938800
848 848 c, t dbSNP:775588286
849 849 a, g, t dbSNP:746102559
858 858 c, t dbSNP:774596862
861 861 c, t dbSNP:771208295
862 862 a, g dbSNP:749603296
870 870 a, g dbSNP:146860442
878 878 c, t dbSNP:756749130
887 887 c, t dbSNP:143797113
888 888 c, g dbSNP:779757519
894 894 c, t dbSNP:373672296
898 898 a, g dbSNP:377158611
911 911 a, c, t dbSNP:75617474
912 912 a, c, g dbSNP:756847536
920 920 c, t dbSNP:140196815
921 921 a, g dbSNP:763846537
922 922 c, t dbSNP:760657763
924 924 c, t dbSNP:373226526
925 925 a, g dbSNP:767528825
934 934 a, g dbSNP:759597838
938 938 c, t dbSNP:774446882
939 939 a, g dbSNP:369688436
942 942 g, t dbSNP:749515217
950 950 c, t dbSNP:773749542
955 955 c, g dbSNP:770259212
958 958 g, t dbSNP:375904468
960 960 a, c, t dbSNP:771486433
961 961 a, g dbSNP:745441972
967 967 c, t dbSNP:778283119
971 971 a, g dbSNP:755393537
979 979 c, t dbSNP:372105353
986 986 c, t dbSNP:200651246
987 987 a, c, g dbSNP:144371384
989 989 c, t dbSNP:374682296
990 990 a, g dbSNP:374840285
1002 1002 a, c dbSNP:760219487
1004 1004 c, t dbSNP:564851292
1005 1005 a, g dbSNP:763313658
1013 1013 c, t dbSNP:149671826
1017 1017 c, t dbSNP:184035890
1020 1020 c, t dbSNP:139437157
1021 1021 a, g dbSNP:371297575
1023 1023 a, c dbSNP:769272352
1024 1024 a, c dbSNP:747443576
1032 1032 c, t dbSNP:61745291
1040 1040 c, t dbSNP:770382134
1045 1045 g, t dbSNP:748973638
1056 1056 c, t dbSNP:143566360
1060 1060 a, c, g, t dbSNP:548981290
1061 1061 a, g dbSNP:752592093
1062 1062 a, g dbSNP:387907414
1063 1063 -, g dbSNP:761918152
1063 1063 a, g, t dbSNP:138008896
1063 1063 -, g dbSNP:772380452
1064 1064 c, t dbSNP:751427421
1073 1073 c, t dbSNP:766586533
1080 1080 a, g dbSNP:763085148
1085 1085 c, t dbSNP:750677498
1086 1086 a, g dbSNP:219780
1089 1089 c, t dbSNP:149733854
1092 1092 c, t dbSNP:554611270
1093 1093 a, g dbSNP:786204841
1107 1107 c, t dbSNP:774161015
1108 1108 a, g dbSNP:768382153
1113 1113 a, c dbSNP:761269316
1114 1114 a, g dbSNP:201218449
1125 1125 c, t dbSNP:770435259
1129 1129 c, g dbSNP:139628442
1130 1130 c, t dbSNP:772699208
1141 1141 c, t dbSNP:769498667
1142 1142 a, c dbSNP:747720793
1149 1149 g, t dbSNP:781087324
1152 1152 a, g dbSNP:754677688
1154 1154 a, g dbSNP:746997205
1163 1163 c, t dbSNP:780070024
1166 1166 c, t dbSNP:758566130
1167 1167 a, g dbSNP:199523516
1169 1169 a, c dbSNP:765378283
1170 1170 a, g dbSNP:114551506
1185 1185 a, g dbSNP:369966830
1226 1226 a, g dbSNP:112112443
1284 1284 a, g dbSNP:150553857
1294 1294 a, g dbSNP:565686905
1329 1329 a, g dbSNP:567389844
1333 1333 -, a dbSNP:547523762
1349 1349 c, t dbSNP:547541223
1353 1353 c, t dbSNP:527363387
1370 1370 a, t dbSNP:746123433
1388 1388 c, g dbSNP:571301747
1396 1396 c, t dbSNP:551351878
1416 1416 a, c, g dbSNP:532695308
1423 1423 c, g dbSNP:377710646
1453 1453 a, g dbSNP:142629054
1454 1454 a, c dbSNP:185515617
1465 1465 -, ggtttt dbSNP:370594336
1466 1466 g, t dbSNP:201508874

Target ORF information:

RefSeq Version XM_011529519
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens claudin 14 (CLDN14), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011529519

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
ATGGCCAGCA CGGCCGTGCA GCTTCTGGGC TTCCTGCTCA GCTTCCTGGG CATGGTGGGC 
ACGTTGATCA CCACCATCCT GCCGCACTGG CGGAGGACAG CGCACGTGGG CACCAACATC
CTCACGGCCG TGTCCTACCT GAAAGGGCTC TGGATGGAGT GTGTGTGGCA CAGCACAGGC
ATCTACCAGT GCCAGATCTA CCGATCCCTG CTGGCGCTGC CCCAAGACCT CCAGGCTGCC
CGCGCCCTCA TGGTCATCTC CTGCCTGCTC TCGGGCATAG CCTGCGCCTG CGCCGTCATC
GGGATGAAGT GCACGCGCTG CGCCAAGGGC ACACCCGCCA AGACCACCTT TGCCATCCTC
GGCGGCACCC TCTTCATCCT GGCCGGCCTC CTGTGCATGG TGGCCGTCTC CTGGACCACC
AACGACGTGG TGCAGAACTT CTACAACCCG CTGCTGCCCA GCGGCATGAA GTTTGAGATT
GGCCAGGCCC TGTACCTGGG CTTCATCTCC TCGTCCCTCT CGCTCATTGG TGGCACCCTG
CTTTGCCTGT CCTGCCAGGA CGAGGCACCC TACAGGCCCT ACCAGGCCCC GCCCAGGGCC
ACCACGACCA CTGCAAACAC CGCACCTGCC TACCAGCCAC CAGCTGCCTA CAAAGACAAT
CGGGCCCCCT CAGTGACCTC GGCCACGCAC AGCGGGTACA GGCTGAACGA CTACGTGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu20415
Accession Version NM_001146078.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 720bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product claudin-14
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AI655909.1, AJ566765.1 and BC012126.1. On Jul 3, 2012 this sequence version replaced gi:225703139. Summary: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. The encoded protein also binds specifically to the WW domain of Yes-associated protein. Defects in this gene are the cause of an autosomal recessive form of nonsyndromic sensorineural deafness. It is also reported that four synonymous variants in this gene are associated with kidney stones and reduced bone mineral density. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jun 2010]. Transcript Variant: This variant (gamma) differs in the 5' UTR compared to variant 1. All five variants encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AJ566765.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145774, SAMEA962348 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
ATGGCCAGCA CGGCCGTGCA GCTTCTGGGC TTCCTGCTCA GCTTCCTGGG CATGGTGGGC 
ACGTTGATCA CCACCATCCT GCCGCACTGG CGGAGGACAG CGCACGTGGG CACCAACATC
CTCACGGCCG TGTCCTACCT GAAAGGGCTC TGGATGGAGT GTGTGTGGCA CAGCACAGGC
ATCTACCAGT GCCAGATCTA CCGATCCCTG CTGGCGCTGC CCCAAGACCT CCAGGCTGCC
CGCGCCCTCA TGGTCATCTC CTGCCTGCTC TCGGGCATAG CCTGCGCCTG CGCCGTCATC
GGGATGAAGT GCACGCGCTG CGCCAAGGGC ACACCCGCCA AGACCACCTT TGCCATCCTC
GGCGGCACCC TCTTCATCCT GGCCGGCCTC CTGTGCATGG TGGCCGTCTC CTGGACCACC
AACGACGTGG TGCAGAACTT CTACAACCCG CTGCTGCCCA GCGGCATGAA GTTTGAGATT
GGCCAGGCCC TGTACCTGGG CTTCATCTCC TCGTCCCTCT CGCTCATTGG TGGCACCCTG
CTTTGCCTGT CCTGCCAGGA CGAGGCACCC TACAGGCCCT ACCAGGCCCC GCCCAGGGCC
ACCACGACCA CTGCAAACAC CGCACCTGCC TACCAGCCAC CAGCTGCCTA CAAAGACAAT
CGGGCCCCCT CAGTGACCTC GGCCACGCAC AGCGGGTACA GGCTGAACGA CTACGTGTGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_001139550.1
CDS475..1194
Misc Feature(1)457..459(+)
Misc Feature(2)496..558(+)
Misc Feature(3)541..1017(+)
Misc Feature(4)718..780(+)
Misc Feature(5)820..882(+)
Misc Feature(6)961..1023(+)
Exon (1)1..255
Gene:CLDN14
Gene Synonym:
Exon (2)256..393
Gene:CLDN14
Gene Synonym:
Exon (3)394..1549
Gene:CLDN14
Gene Synonym:
Translation
Position Chain Variation Link
2 2 a, g dbSNP:529399287
37 37 c, t dbSNP:560332085
87 87 c, t dbSNP:762940542
93 93 a, c dbSNP:540600995
105 105 g, t dbSNP:565202879
183 183 -, c dbSNP:753488846
193 193 c, g dbSNP:928839
260 260 c, t dbSNP:543178465
261 261 a, g dbSNP:529450999
278 278 c, g dbSNP:776693720
325 325 c, t dbSNP:57668637
342 342 a, g dbSNP:769191161
355 355 a, c dbSNP:747570919
371 371 c, t dbSNP:184746529
374 374 -, tt dbSNP:59563067
399 399 c, t dbSNP:557122405
400 400 a, g, t dbSNP:537529014
417 417 c, t dbSNP:759652223
418 418 a, g dbSNP:188479887
422 422 g, t dbSNP:548165835
429 429 a, g dbSNP:779699092
438 438 a, g dbSNP:149049781
449 449 a, g dbSNP:758426367
450 450 c, g dbSNP:750364874
470 470 a, g dbSNP:368231049
484 484 a, g dbSNP:374578221
485 485 c, t dbSNP:113831133
486 486 a, g dbSNP:764358289
489 489 c, t dbSNP:387907416
490 490 a, g dbSNP:202117396
492 492 a, g dbSNP:387907417
502 502 c, g dbSNP:772295911
525 525 c, t dbSNP:150040476
526 526 a, g dbSNP:369883669
529 529 g, t dbSNP:769320772
534 534 c, t dbSNP:387907415
536 536 c, t dbSNP:532176130
537 537 a, g dbSNP:117560775
538 538 -, ttg dbSNP:762948927
541 541 a, c dbSNP:780834768
542 542 c, t dbSNP:768411939
546 546 c, t dbSNP:549639383
548 548 c, t dbSNP:779937857
556 556 c, t dbSNP:758081638
557 557 c, t dbSNP:727504989
558 558 a, g dbSNP:778927942
565 565 c, t dbSNP:757426764
575 575 a, c dbSNP:754032374
576 576 a, g dbSNP:146395322
579 579 c, t dbSNP:560763542
580 580 a, g, t dbSNP:142205038
583 583 a, g dbSNP:759850341
590 590 -, aca dbSNP:752639706
599 599 c, t dbSNP:533194857
600 600 a, g dbSNP:140177046
603 603 c, t dbSNP:150731625
604 604 a, g dbSNP:141139613
633 633 a, g dbSNP:768019537
636 636 c, t dbSNP:746698259
638 638 c, t dbSNP:752960573
641 641 -, gg dbSNP:765103185
641 641 a, g dbSNP:371100799
643 643 c, t dbSNP:745601274
645 645 c, t dbSNP:778842030
655 655 a, t dbSNP:757334760
659 659 a, g dbSNP:148223897
669 669 a, g dbSNP:777960789
669 669 -, g dbSNP:760769965
677 677 a, g dbSNP:756095919
682 682 c, g dbSNP:752992781
683 683 g, t dbSNP:767565332
685 685 c, t dbSNP:755346413
689 689 c, t dbSNP:573588226
690 690 a, g dbSNP:370315827
692 692 a, t dbSNP:763489263
697 697 c, t dbSNP:560052879
702 702 c, t dbSNP:763692550
708 708 c, g dbSNP:760039736
713 713 c, t dbSNP:775222236
715 715 c, t dbSNP:143628692
716 716 a, g dbSNP:368027306
717 717 c, t dbSNP:219779
727 727 g, t dbSNP:770829440
728 728 a, t dbSNP:74315437
734 734 c, g dbSNP:777529810
736 736 c, t dbSNP:756218341
741 741 g, t dbSNP:748115585
742 742 c, g dbSNP:781318012
747 747 a, g dbSNP:577393948
750 750 c, g dbSNP:751747842
751 751 a, t dbSNP:780444223
754 754 c, g dbSNP:758724049
759 759 c, t dbSNP:750946312
760 760 a, g dbSNP:765605373
761 761 c, t dbSNP:762368755
765 765 a, c, t dbSNP:767108790
766 766 a, g dbSNP:759313432
768 768 -, tgcgcc dbSNP:773126341
768 768 c, t dbSNP:374400022
769 769 a, g dbSNP:371106978
773 773 c, t dbSNP:557513586
774 774 c, t dbSNP:113350364
775 775 a, g dbSNP:74315438
788 788 c, t dbSNP:748110915
789 789 a, g dbSNP:781167430
790 790 c, t dbSNP:140257182
791 791 a, g dbSNP:747254086
795 795 c, t dbSNP:764548516
796 796 a, g dbSNP:377019596
797 797 c, t dbSNP:373823945
809 809 a, c, t dbSNP:555911451
810 810 c, g, t dbSNP:754350037
811 811 a, c, g dbSNP:138631461
821 821 a, c, t dbSNP:370342285
826 826 a, c, g dbSNP:377333347
835 835 a, g dbSNP:150201704
837 837 c, t dbSNP:763411863
838 838 a, g dbSNP:769599110
843 843 a, c, t dbSNP:727502938
849 849 c, t dbSNP:768728088
853 853 c, t dbSNP:747033624
858 858 c, t dbSNP:780095902
859 859 a, g dbSNP:772250957
861 861 c, t dbSNP:558404405
866 866 c, t dbSNP:373777126
871 871 a, g dbSNP:757597772
872 872 -, t dbSNP:786200885
880 880 a, g dbSNP:140918123
887 887 a, g dbSNP:151069240
888 888 a, g dbSNP:142846225
893 893 c, t dbSNP:754545220
896 896 a, c dbSNP:751170450
897 897 a, c, t dbSNP:758024791
898 898 a, g dbSNP:146755542
900 900 c, t dbSNP:140671150
901 901 a, c, g dbSNP:776564488
904 904 a, g dbSNP:764077250
918 918 c, t dbSNP:549938800
923 923 c, t dbSNP:775588286
924 924 a, g, t dbSNP:746102559
933 933 c, t dbSNP:774596862
936 936 c, t dbSNP:771208295
937 937 a, g dbSNP:749603296
945 945 a, g dbSNP:146860442
953 953 c, t dbSNP:756749130
962 962 c, t dbSNP:143797113
963 963 c, g dbSNP:779757519
969 969 c, t dbSNP:373672296
973 973 a, g dbSNP:377158611
986 986 a, c, t dbSNP:75617474
987 987 a, c, g dbSNP:756847536
995 995 c, t dbSNP:140196815
996 996 a, g dbSNP:763846537
997 997 c, t dbSNP:760657763
999 999 c, t dbSNP:373226526
1000 1000 a, g dbSNP:767528825
1009 1009 a, g dbSNP:759597838
1013 1013 c, t dbSNP:774446882
1014 1014 a, g dbSNP:369688436
1017 1017 g, t dbSNP:749515217
1025 1025 c, t dbSNP:773749542
1030 1030 c, g dbSNP:770259212
1033 1033 g, t dbSNP:375904468
1035 1035 a, c, t dbSNP:771486433
1036 1036 a, g dbSNP:745441972
1042 1042 c, t dbSNP:778283119
1046 1046 a, g dbSNP:755393537
1054 1054 c, t dbSNP:372105353
1061 1061 c, t dbSNP:200651246
1062 1062 a, c, g dbSNP:144371384
1064 1064 c, t dbSNP:374682296
1065 1065 a, g dbSNP:374840285
1077 1077 a, c dbSNP:760219487
1079 1079 c, t dbSNP:564851292
1080 1080 a, g dbSNP:763313658
1088 1088 c, t dbSNP:149671826
1092 1092 c, t dbSNP:184035890
1095 1095 c, t dbSNP:139437157
1096 1096 a, g dbSNP:371297575
1098 1098 a, c dbSNP:769272352
1099 1099 a, c dbSNP:747443576
1107 1107 c, t dbSNP:61745291
1115 1115 c, t dbSNP:770382134
1120 1120 g, t dbSNP:748973638
1131 1131 c, t dbSNP:143566360
1135 1135 a, c, g, t dbSNP:548981290
1136 1136 a, g dbSNP:752592093
1137 1137 a, g dbSNP:387907414
1138 1138 -, g dbSNP:761918152
1138 1138 a, g, t dbSNP:138008896
1138 1138 -, g dbSNP:772380452
1139 1139 c, t dbSNP:751427421
1148 1148 c, t dbSNP:766586533
1155 1155 a, g dbSNP:763085148
1160 1160 c, t dbSNP:750677498
1161 1161 a, g dbSNP:219780
1164 1164 c, t dbSNP:149733854
1167 1167 c, t dbSNP:554611270
1168 1168 a, g dbSNP:786204841
1182 1182 c, t dbSNP:774161015
1183 1183 a, g dbSNP:768382153
1188 1188 a, c dbSNP:761269316
1189 1189 a, g dbSNP:201218449
1200 1200 c, t dbSNP:770435259
1204 1204 c, g dbSNP:139628442
1205 1205 c, t dbSNP:772699208
1216 1216 c, t dbSNP:769498667
1217 1217 a, c dbSNP:747720793
1224 1224 g, t dbSNP:781087324
1227 1227 a, g dbSNP:754677688
1229 1229 a, g dbSNP:746997205
1238 1238 c, t dbSNP:780070024
1241 1241 c, t dbSNP:758566130
1242 1242 a, g dbSNP:199523516
1244 1244 a, c dbSNP:765378283
1245 1245 a, g dbSNP:114551506
1260 1260 a, g dbSNP:369966830
1301 1301 a, g dbSNP:112112443
1359 1359 a, g dbSNP:150553857
1369 1369 a, g dbSNP:565686905
1404 1404 a, g dbSNP:567389844
1408 1408 -, a dbSNP:547523762
1424 1424 c, t dbSNP:547541223
1428 1428 c, t dbSNP:527363387
1445 1445 a, t dbSNP:746123433
1463 1463 c, g dbSNP:571301747
1471 1471 c, t dbSNP:551351878
1491 1491 a, c, g dbSNP:532695308
1498 1498 c, g dbSNP:377710646
1528 1528 a, g dbSNP:142629054
1529 1529 a, c dbSNP:185515617
1540 1540 -, ggtttt dbSNP:370594336
1541 1541 g, t dbSNP:201508874

Target ORF information:

RefSeq Version NM_001146078
Organism Homo sapiens (human)
Definition Homo sapiens claudin 14 (CLDN14), transcript variant gamma, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001146078

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
ATGGCCAGCA CGGCCGTGCA GCTTCTGGGC TTCCTGCTCA GCTTCCTGGG CATGGTGGGC 
ACGTTGATCA CCACCATCCT GCCGCACTGG CGGAGGACAG CGCACGTGGG CACCAACATC
CTCACGGCCG TGTCCTACCT GAAAGGGCTC TGGATGGAGT GTGTGTGGCA CAGCACAGGC
ATCTACCAGT GCCAGATCTA CCGATCCCTG CTGGCGCTGC CCCAAGACCT CCAGGCTGCC
CGCGCCCTCA TGGTCATCTC CTGCCTGCTC TCGGGCATAG CCTGCGCCTG CGCCGTCATC
GGGATGAAGT GCACGCGCTG CGCCAAGGGC ACACCCGCCA AGACCACCTT TGCCATCCTC
GGCGGCACCC TCTTCATCCT GGCCGGCCTC CTGTGCATGG TGGCCGTCTC CTGGACCACC
AACGACGTGG TGCAGAACTT CTACAACCCG CTGCTGCCCA GCGGCATGAA GTTTGAGATT
GGCCAGGCCC TGTACCTGGG CTTCATCTCC TCGTCCCTCT CGCTCATTGG TGGCACCCTG
CTTTGCCTGT CCTGCCAGGA CGAGGCACCC TACAGGCCCT ACCAGGCCCC GCCCAGGGCC
ACCACGACCA CTGCAAACAC CGCACCTGCC TACCAGCCAC CAGCTGCCTA CAAAGACAAT
CGGGCCCCCT CAGTGACCTC GGCCACGCAC AGCGGGTACA GGCTGAACGA CTACGTGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu20415
Accession Version NM_001146077.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 720bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product claudin-14
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AJ566766.1 and BC012126.1. This sequence is a reference standard in the RefSeqGene project. Summary: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. The encoded protein also binds specifically to the WW domain of Yes-associated protein. Defects in this gene are the cause of an autosomal recessive form of nonsyndromic sensorineural deafness. It is also reported that four synonymous variants in this gene are associated with kidney stones and reduced bone mineral density. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jun 2010]. Transcript Variant: This variant (delta) differs in the 5' UTR compared to variant 1. All five variants encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AJ566766.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1968968, SAMEA2145774 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
ATGGCCAGCA CGGCCGTGCA GCTTCTGGGC TTCCTGCTCA GCTTCCTGGG CATGGTGGGC 
ACGTTGATCA CCACCATCCT GCCGCACTGG CGGAGGACAG CGCACGTGGG CACCAACATC
CTCACGGCCG TGTCCTACCT GAAAGGGCTC TGGATGGAGT GTGTGTGGCA CAGCACAGGC
ATCTACCAGT GCCAGATCTA CCGATCCCTG CTGGCGCTGC CCCAAGACCT CCAGGCTGCC
CGCGCCCTCA TGGTCATCTC CTGCCTGCTC TCGGGCATAG CCTGCGCCTG CGCCGTCATC
GGGATGAAGT GCACGCGCTG CGCCAAGGGC ACACCCGCCA AGACCACCTT TGCCATCCTC
GGCGGCACCC TCTTCATCCT GGCCGGCCTC CTGTGCATGG TGGCCGTCTC CTGGACCACC
AACGACGTGG TGCAGAACTT CTACAACCCG CTGCTGCCCA GCGGCATGAA GTTTGAGATT
GGCCAGGCCC TGTACCTGGG CTTCATCTCC TCGTCCCTCT CGCTCATTGG TGGCACCCTG
CTTTGCCTGT CCTGCCAGGA CGAGGCACCC TACAGGCCCT ACCAGGCCCC GCCCAGGGCC
ACCACGACCA CTGCAAACAC CGCACCTGCC TACCAGCCAC CAGCTGCCTA CAAAGACAAT
CGGGCCCCCT CAGTGACCTC GGCCACGCAC AGCGGGTACA GGCTGAACGA CTACGTGTGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_001139549.1
CDS379..1098
Misc Feature(1)361..363(+)
Misc Feature(2)400..462(+)
Misc Feature(3)445..921(+)
Misc Feature(4)622..684(+)
Misc Feature(5)724..786(+)
Misc Feature(6)865..927(+)
Exon (1)1..159
Gene:CLDN14
Gene Synonym:
Exon (2)160..297
Gene:CLDN14
Gene Synonym:
Exon (3)298..1453
Gene:CLDN14
Gene Synonym:
Translation
Position Chain Variation Link
37 37 a, c dbSNP:557736634
57 57 c, t dbSNP:7283441
91 91 a, g dbSNP:570375315
104 104 g, t dbSNP:777858259
130 130 a, g dbSNP:550188093
149 149 a, g dbSNP:7275192
150 150 a, c dbSNP:752527705
158 158 c, t dbSNP:75497102
164 164 c, t dbSNP:543178465
165 165 a, g dbSNP:529450999
182 182 c, g dbSNP:776693720
229 229 c, t dbSNP:57668637
246 246 a, g dbSNP:769191161
259 259 a, c dbSNP:747570919
275 275 c, t dbSNP:184746529
278 278 -, tt dbSNP:59563067
303 303 c, t dbSNP:557122405
304 304 a, g, t dbSNP:537529014
321 321 c, t dbSNP:759652223
322 322 a, g dbSNP:188479887
326 326 g, t dbSNP:548165835
333 333 a, g dbSNP:779699092
342 342 a, g dbSNP:149049781
353 353 a, g dbSNP:758426367
354 354 c, g dbSNP:750364874
374 374 a, g dbSNP:368231049
388 388 a, g dbSNP:374578221
389 389 c, t dbSNP:113831133
390 390 a, g dbSNP:764358289
393 393 c, t dbSNP:387907416
394 394 a, g dbSNP:202117396
396 396 a, g dbSNP:387907417
406 406 c, g dbSNP:772295911
429 429 c, t dbSNP:150040476
430 430 a, g dbSNP:369883669
433 433 g, t dbSNP:769320772
438 438 c, t dbSNP:387907415
440 440 c, t dbSNP:532176130
441 441 a, g dbSNP:117560775
442 442 -, ttg dbSNP:762948927
445 445 a, c dbSNP:780834768
446 446 c, t dbSNP:768411939
450 450 c, t dbSNP:549639383
452 452 c, t dbSNP:779937857
460 460 c, t dbSNP:758081638
461 461 c, t dbSNP:727504989
462 462 a, g dbSNP:778927942
469 469 c, t dbSNP:757426764
479 479 a, c dbSNP:754032374
480 480 a, g dbSNP:146395322
483 483 c, t dbSNP:560763542
484 484 a, g, t dbSNP:142205038
487 487 a, g dbSNP:759850341
494 494 -, aca dbSNP:752639706
503 503 c, t dbSNP:533194857
504 504 a, g dbSNP:140177046
507 507 c, t dbSNP:150731625
508 508 a, g dbSNP:141139613
537 537 a, g dbSNP:768019537
540 540 c, t dbSNP:746698259
542 542 c, t dbSNP:752960573
545 545 -, gg dbSNP:765103185
545 545 a, g dbSNP:371100799
547 547 c, t dbSNP:745601274
549 549 c, t dbSNP:778842030
559 559 a, t dbSNP:757334760
563 563 a, g dbSNP:148223897
573 573 a, g dbSNP:777960789
573 573 -, g dbSNP:760769965
581 581 a, g dbSNP:756095919
586 586 c, g dbSNP:752992781
587 587 g, t dbSNP:767565332
589 589 c, t dbSNP:755346413
593 593 c, t dbSNP:573588226
594 594 a, g dbSNP:370315827
596 596 a, t dbSNP:763489263
601 601 c, t dbSNP:560052879
606 606 c, t dbSNP:763692550
612 612 c, g dbSNP:760039736
617 617 c, t dbSNP:775222236
619 619 c, t dbSNP:143628692
620 620 a, g dbSNP:368027306
621 621 c, t dbSNP:219779
631 631 g, t dbSNP:770829440
632 632 a, t dbSNP:74315437
638 638 c, g dbSNP:777529810
640 640 c, t dbSNP:756218341
645 645 g, t dbSNP:748115585
646 646 c, g dbSNP:781318012
651 651 a, g dbSNP:577393948
654 654 c, g dbSNP:751747842
655 655 a, t dbSNP:780444223
658 658 c, g dbSNP:758724049
663 663 c, t dbSNP:750946312
664 664 a, g dbSNP:765605373
665 665 c, t dbSNP:762368755
669 669 a, c, t dbSNP:767108790
670 670 a, g dbSNP:759313432
672 672 -, tgcgcc dbSNP:773126341
672 672 c, t dbSNP:374400022
673 673 a, g dbSNP:371106978
677 677 c, t dbSNP:557513586
678 678 c, t dbSNP:113350364
679 679 a, g dbSNP:74315438
692 692 c, t dbSNP:748110915
693 693 a, g dbSNP:781167430
694 694 c, t dbSNP:140257182
695 695 a, g dbSNP:747254086
699 699 c, t dbSNP:764548516
700 700 a, g dbSNP:377019596
701 701 c, t dbSNP:373823945
713 713 a, c, t dbSNP:555911451
714 714 c, g, t dbSNP:754350037
715 715 a, c, g dbSNP:138631461
725 725 a, c, t dbSNP:370342285
730 730 a, c, g dbSNP:377333347
739 739 a, g dbSNP:150201704
741 741 c, t dbSNP:763411863
742 742 a, g dbSNP:769599110
747 747 a, c, t dbSNP:727502938
753 753 c, t dbSNP:768728088
757 757 c, t dbSNP:747033624
762 762 c, t dbSNP:780095902
763 763 a, g dbSNP:772250957
765 765 c, t dbSNP:558404405
770 770 c, t dbSNP:373777126
775 775 a, g dbSNP:757597772
776 776 -, t dbSNP:786200885
784 784 a, g dbSNP:140918123
791 791 a, g dbSNP:151069240
792 792 a, g dbSNP:142846225
797 797 c, t dbSNP:754545220
800 800 a, c dbSNP:751170450
801 801 a, c, t dbSNP:758024791
802 802 a, g dbSNP:146755542
804 804 c, t dbSNP:140671150
805 805 a, c, g dbSNP:776564488
808 808 a, g dbSNP:764077250
822 822 c, t dbSNP:549938800
827 827 c, t dbSNP:775588286
828 828 a, g, t dbSNP:746102559
837 837 c, t dbSNP:774596862
840 840 c, t dbSNP:771208295
841 841 a, g dbSNP:749603296
849 849 a, g dbSNP:146860442
857 857 c, t dbSNP:756749130
866 866 c, t dbSNP:143797113
867 867 c, g dbSNP:779757519
873 873 c, t dbSNP:373672296
877 877 a, g dbSNP:377158611
890 890 a, c, t dbSNP:75617474
891 891 a, c, g dbSNP:756847536
899 899 c, t dbSNP:140196815
900 900 a, g dbSNP:763846537
901 901 c, t dbSNP:760657763
903 903 c, t dbSNP:373226526
904 904 a, g dbSNP:767528825
913 913 a, g dbSNP:759597838
917 917 c, t dbSNP:774446882
918 918 a, g dbSNP:369688436
921 921 g, t dbSNP:749515217
929 929 c, t dbSNP:773749542
934 934 c, g dbSNP:770259212
937 937 g, t dbSNP:375904468
939 939 a, c, t dbSNP:771486433
940 940 a, g dbSNP:745441972
946 946 c, t dbSNP:778283119
950 950 a, g dbSNP:755393537
958 958 c, t dbSNP:372105353
965 965 c, t dbSNP:200651246
966 966 a, c, g dbSNP:144371384
968 968 c, t dbSNP:374682296
969 969 a, g dbSNP:374840285
981 981 a, c dbSNP:760219487
983 983 c, t dbSNP:564851292
984 984 a, g dbSNP:763313658
992 992 c, t dbSNP:149671826
996 996 c, t dbSNP:184035890
999 999 c, t dbSNP:139437157
1000 1000 a, g dbSNP:371297575
1002 1002 a, c dbSNP:769272352
1003 1003 a, c dbSNP:747443576
1011 1011 c, t dbSNP:61745291
1019 1019 c, t dbSNP:770382134
1024 1024 g, t dbSNP:748973638
1035 1035 c, t dbSNP:143566360
1039 1039 a, c, g, t dbSNP:548981290
1040 1040 a, g dbSNP:752592093
1041 1041 a, g dbSNP:387907414
1042 1042 -, g dbSNP:761918152
1042 1042 a, g, t dbSNP:138008896
1042 1042 -, g dbSNP:772380452
1043 1043 c, t dbSNP:751427421
1052 1052 c, t dbSNP:766586533
1059 1059 a, g dbSNP:763085148
1064 1064 c, t dbSNP:750677498
1065 1065 a, g dbSNP:219780
1068 1068 c, t dbSNP:149733854
1071 1071 c, t dbSNP:554611270
1072 1072 a, g dbSNP:786204841
1086 1086 c, t dbSNP:774161015
1087 1087 a, g dbSNP:768382153
1092 1092 a, c dbSNP:761269316
1093 1093 a, g dbSNP:201218449
1104 1104 c, t dbSNP:770435259
1108 1108 c, g dbSNP:139628442
1109 1109 c, t dbSNP:772699208
1120 1120 c, t dbSNP:769498667
1121 1121 a, c dbSNP:747720793
1128 1128 g, t dbSNP:781087324
1131 1131 a, g dbSNP:754677688
1133 1133 a, g dbSNP:746997205
1142 1142 c, t dbSNP:780070024
1145 1145 c, t dbSNP:758566130
1146 1146 a, g dbSNP:199523516
1148 1148 a, c dbSNP:765378283
1149 1149 a, g dbSNP:114551506
1164 1164 a, g dbSNP:369966830
1205 1205 a, g dbSNP:112112443
1263 1263 a, g dbSNP:150553857
1273 1273 a, g dbSNP:565686905
1308 1308 a, g dbSNP:567389844
1312 1312 -, a dbSNP:547523762
1328 1328 c, t dbSNP:547541223
1332 1332 c, t dbSNP:527363387
1349 1349 a, t dbSNP:746123433
1367 1367 c, g dbSNP:571301747
1375 1375 c, t dbSNP:551351878
1395 1395 a, c, g dbSNP:532695308
1402 1402 c, g dbSNP:377710646
1432 1432 a, g dbSNP:142629054
1433 1433 a, c dbSNP:185515617
1444 1444 -, ggtttt dbSNP:370594336
1445 1445 g, t dbSNP:201508874

Target ORF information:

RefSeq Version NM_001146077
Organism Homo sapiens (human)
Definition Homo sapiens claudin 14 (CLDN14), transcript variant 3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001146077

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
ATGGCCAGCA CGGCCGTGCA GCTTCTGGGC TTCCTGCTCA GCTTCCTGGG CATGGTGGGC 
ACGTTGATCA CCACCATCCT GCCGCACTGG CGGAGGACAG CGCACGTGGG CACCAACATC
CTCACGGCCG TGTCCTACCT GAAAGGGCTC TGGATGGAGT GTGTGTGGCA CAGCACAGGC
ATCTACCAGT GCCAGATCTA CCGATCCCTG CTGGCGCTGC CCCAAGACCT CCAGGCTGCC
CGCGCCCTCA TGGTCATCTC CTGCCTGCTC TCGGGCATAG CCTGCGCCTG CGCCGTCATC
GGGATGAAGT GCACGCGCTG CGCCAAGGGC ACACCCGCCA AGACCACCTT TGCCATCCTC
GGCGGCACCC TCTTCATCCT GGCCGGCCTC CTGTGCATGG TGGCCGTCTC CTGGACCACC
AACGACGTGG TGCAGAACTT CTACAACCCG CTGCTGCCCA GCGGCATGAA GTTTGAGATT
GGCCAGGCCC TGTACCTGGG CTTCATCTCC TCGTCCCTCT CGCTCATTGG TGGCACCCTG
CTTTGCCTGT CCTGCCAGGA CGAGGCACCC TACAGGCCCT ACCAGGCCCC GCCCAGGGCC
ACCACGACCA CTGCAAACAC CGCACCTGCC TACCAGCCAC CAGCTGCCTA CAAAGACAAT
CGGGCCCCCT CAGTGACCTC GGCCACGCAC AGCGGGTACA GGCTGAACGA CTACGTGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu20415
Accession Version NM_144492.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 720bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product claudin-14
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF314090.1, AP000695.1 and BC012126.1. On Mar 27, 2009 this sequence version replaced gi:21536293. Summary: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. The encoded protein also binds specifically to the WW domain of Yes-associated protein. Defects in this gene are the cause of an autosomal recessive form of nonsyndromic sensorineural deafness. It is also reported that four synonymous variants in this gene are associated with kidney stones and reduced bone mineral density. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jun 2010]. Transcript Variant: This variant (alpha) represents the longest transcript. All five variants encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF314090.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145122, SAMEA2162895 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
ATGGCCAGCA CGGCCGTGCA GCTTCTGGGC TTCCTGCTCA GCTTCCTGGG CATGGTGGGC 
ACGTTGATCA CCACCATCCT GCCGCACTGG CGGAGGACAG CGCACGTGGG CACCAACATC
CTCACGGCCG TGTCCTACCT GAAAGGGCTC TGGATGGAGT GTGTGTGGCA CAGCACAGGC
ATCTACCAGT GCCAGATCTA CCGATCCCTG CTGGCGCTGC CCCAAGACCT CCAGGCTGCC
CGCGCCCTCA TGGTCATCTC CTGCCTGCTC TCGGGCATAG CCTGCGCCTG CGCCGTCATC
GGGATGAAGT GCACGCGCTG CGCCAAGGGC ACACCCGCCA AGACCACCTT TGCCATCCTC
GGCGGCACCC TCTTCATCCT GGCCGGCCTC CTGTGCATGG TGGCCGTCTC CTGGACCACC
AACGACGTGG TGCAGAACTT CTACAACCCG CTGCTGCCCA GCGGCATGAA GTTTGAGATT
GGCCAGGCCC TGTACCTGGG CTTCATCTCC TCGTCCCTCT CGCTCATTGG TGGCACCCTG
CTTTGCCTGT CCTGCCAGGA CGAGGCACCC TACAGGCCCT ACCAGGCCCC GCCCAGGGCC
ACCACGACCA CTGCAAACAC CGCACCTGCC TACCAGCCAC CAGCTGCCTA CAAAGACAAT
CGGGCCCCCT CAGTGACCTC GGCCACGCAC AGCGGGTACA GGCTGAACGA CTACGTGTGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_652763.1
CDS868..1587
Misc Feature(1)850..852(+)
Misc Feature(2)889..951(+)
Misc Feature(3)934..1410(+)
Misc Feature(4)1111..1173(+)
Misc Feature(5)1213..1275(+)
Misc Feature(6)1354..1416(+)
Exon (1)1..596
Gene:CLDN14
Gene Synonym:
Exon (2)597..786
Gene:CLDN14
Gene Synonym:
Exon (3)787..1942
Gene:CLDN14
Gene Synonym:
Translation
Position Chain Variation Link
1 1 c, t dbSNP:553132355
23 23 -, gga dbSNP:139003220
48 48 g, t dbSNP:375811545
55 55 a, g dbSNP:528517263
146 146 c, t dbSNP:559813058
147 147 a, g dbSNP:372584176
153 153 c, g dbSNP:116629563
199 199 c, t dbSNP:376942377
233 233 a, g dbSNP:557217395
242 242 a, g dbSNP:543253636
274 274 a, t dbSNP:370189669
282 282 c, t dbSNP:574250923
288 288 a, g dbSNP:150344346
341 341 c, g dbSNP:117804848
347 347 -, t dbSNP:758408442
370 370 c, t dbSNP:778118245
381 381 a, g dbSNP:140333712
388 388 a, g dbSNP:219742
414 414 c, g dbSNP:188733
436 436 c, t dbSNP:78291168
437 437 a, g dbSNP:551215354
439 439 c, t dbSNP:369614226
448 448 a, g dbSNP:151272065
483 483 c, t dbSNP:548778387
487 487 a, g dbSNP:528630078
492 492 a, g dbSNP:181645276
495 495 c, t dbSNP:376974087
508 508 a, g dbSNP:552336543
534 534 c, t dbSNP:754434925
541 541 c, t dbSNP:372217521
547 547 c, t dbSNP:114492024
548 548 a, g dbSNP:537704763
583 583 a, g dbSNP:563441963
603 603 a, c dbSNP:527619994
610 610 c, t dbSNP:760334550
676 676 c, g dbSNP:543094379
689 689 a, g dbSNP:73902533
708 708 a, g dbSNP:181028658
710 710 a, c dbSNP:771801058
720 720 a, c dbSNP:748396698
755 755 c, t dbSNP:28653283
792 792 c, t dbSNP:557122405
793 793 a, g, t dbSNP:537529014
810 810 c, t dbSNP:759652223
811 811 a, g dbSNP:188479887
815 815 g, t dbSNP:548165835
822 822 a, g dbSNP:779699092
831 831 a, g dbSNP:149049781
842 842 a, g dbSNP:758426367
843 843 c, g dbSNP:750364874
863 863 a, g dbSNP:368231049
877 877 a, g dbSNP:374578221
878 878 c, t dbSNP:113831133
879 879 a, g dbSNP:764358289
882 882 c, t dbSNP:387907416
883 883 a, g dbSNP:202117396
885 885 a, g dbSNP:387907417
895 895 c, g dbSNP:772295911
918 918 c, t dbSNP:150040476
919 919 a, g dbSNP:369883669
922 922 g, t dbSNP:769320772
927 927 c, t dbSNP:387907415
929 929 c, t dbSNP:532176130
930 930 a, g dbSNP:117560775
931 931 -, ttg dbSNP:762948927
934 934 a, c dbSNP:780834768
935 935 c, t dbSNP:768411939
939 939 c, t dbSNP:549639383
941 941 c, t dbSNP:779937857
949 949 c, t dbSNP:758081638
950 950 c, t dbSNP:727504989
951 951 a, g dbSNP:778927942
958 958 c, t dbSNP:757426764
968 968 a, c dbSNP:754032374
969 969 a, g dbSNP:146395322
972 972 c, t dbSNP:560763542
973 973 a, g, t dbSNP:142205038
976 976 a, g dbSNP:759850341
983 983 -, aca dbSNP:752639706
992 992 c, t dbSNP:533194857
993 993 a, g dbSNP:140177046
996 996 c, t dbSNP:150731625
997 997 a, g dbSNP:141139613
1026 1026 a, g dbSNP:768019537
1029 1029 c, t dbSNP:746698259
1031 1031 c, t dbSNP:752960573
1034 1034 -, gg dbSNP:765103185
1034 1034 a, g dbSNP:371100799
1036 1036 c, t dbSNP:745601274
1038 1038 c, t dbSNP:778842030
1048 1048 a, t dbSNP:757334760
1052 1052 a, g dbSNP:148223897
1062 1062 a, g dbSNP:777960789
1062 1062 -, g dbSNP:760769965
1070 1070 a, g dbSNP:756095919
1075 1075 c, g dbSNP:752992781
1076 1076 g, t dbSNP:767565332
1078 1078 c, t dbSNP:755346413
1082 1082 c, t dbSNP:573588226
1083 1083 a, g dbSNP:370315827
1085 1085 a, t dbSNP:763489263
1090 1090 c, t dbSNP:560052879
1095 1095 c, t dbSNP:763692550
1101 1101 c, g dbSNP:760039736
1106 1106 c, t dbSNP:775222236
1108 1108 c, t dbSNP:143628692
1109 1109 a, g dbSNP:368027306
1110 1110 c, t dbSNP:219779
1120 1120 g, t dbSNP:770829440
1121 1121 a, t dbSNP:74315437
1127 1127 c, g dbSNP:777529810
1129 1129 c, t dbSNP:756218341
1134 1134 g, t dbSNP:748115585
1135 1135 c, g dbSNP:781318012
1140 1140 a, g dbSNP:577393948
1143 1143 c, g dbSNP:751747842
1144 1144 a, t dbSNP:780444223
1147 1147 c, g dbSNP:758724049
1152 1152 c, t dbSNP:750946312
1153 1153 a, g dbSNP:765605373
1154 1154 c, t dbSNP:762368755
1158 1158 a, c, t dbSNP:767108790
1159 1159 a, g dbSNP:759313432
1161 1161 -, tgcgcc dbSNP:773126341
1161 1161 c, t dbSNP:374400022
1162 1162 a, g dbSNP:371106978
1166 1166 c, t dbSNP:557513586
1167 1167 c, t dbSNP:113350364
1168 1168 a, g dbSNP:74315438
1181 1181 c, t dbSNP:748110915
1182 1182 a, g dbSNP:781167430
1183 1183 c, t dbSNP:140257182
1184 1184 a, g dbSNP:747254086
1188 1188 c, t dbSNP:764548516
1189 1189 a, g dbSNP:377019596
1190 1190 c, t dbSNP:373823945
1202 1202 a, c, t dbSNP:555911451
1203 1203 c, g, t dbSNP:754350037
1204 1204 a, c, g dbSNP:138631461
1214 1214 a, c, t dbSNP:370342285
1219 1219 a, c, g dbSNP:377333347
1228 1228 a, g dbSNP:150201704
1230 1230 c, t dbSNP:763411863
1231 1231 a, g dbSNP:769599110
1236 1236 a, c, t dbSNP:727502938
1242 1242 c, t dbSNP:768728088
1246 1246 c, t dbSNP:747033624
1251 1251 c, t dbSNP:780095902
1252 1252 a, g dbSNP:772250957
1254 1254 c, t dbSNP:558404405
1259 1259 c, t dbSNP:373777126
1264 1264 a, g dbSNP:757597772
1265 1265 -, t dbSNP:786200885
1273 1273 a, g dbSNP:140918123
1280 1280 a, g dbSNP:151069240
1281 1281 a, g dbSNP:142846225
1286 1286 c, t dbSNP:754545220
1289 1289 a, c dbSNP:751170450
1290 1290 a, c, t dbSNP:758024791
1291 1291 a, g dbSNP:146755542
1293 1293 c, t dbSNP:140671150
1294 1294 a, c, g dbSNP:776564488
1297 1297 a, g dbSNP:764077250
1311 1311 c, t dbSNP:549938800
1316 1316 c, t dbSNP:775588286
1317 1317 a, g, t dbSNP:746102559
1326 1326 c, t dbSNP:774596862
1329 1329 c, t dbSNP:771208295
1330 1330 a, g dbSNP:749603296
1338 1338 a, g dbSNP:146860442
1346 1346 c, t dbSNP:756749130
1355 1355 c, t dbSNP:143797113
1356 1356 c, g dbSNP:779757519
1362 1362 c, t dbSNP:373672296
1366 1366 a, g dbSNP:377158611
1379 1379 a, c, t dbSNP:75617474
1380 1380 a, c, g dbSNP:756847536
1388 1388 c, t dbSNP:140196815
1389 1389 a, g dbSNP:763846537
1390 1390 c, t dbSNP:760657763
1392 1392 c, t dbSNP:373226526
1393 1393 a, g dbSNP:767528825
1402 1402 a, g dbSNP:759597838
1406 1406 c, t dbSNP:774446882
1407 1407 a, g dbSNP:369688436
1410 1410 g, t dbSNP:749515217
1418 1418 c, t dbSNP:773749542
1423 1423 c, g dbSNP:770259212
1426 1426 g, t dbSNP:375904468
1428 1428 a, c, t dbSNP:771486433
1429 1429 a, g dbSNP:745441972
1435 1435 c, t dbSNP:778283119
1439 1439 a, g dbSNP:755393537
1447 1447 c, t dbSNP:372105353
1454 1454 c, t dbSNP:200651246
1455 1455 a, c, g dbSNP:144371384
1457 1457 c, t dbSNP:374682296
1458 1458 a, g dbSNP:374840285
1470 1470 a, c dbSNP:760219487
1472 1472 c, t dbSNP:564851292
1473 1473 a, g dbSNP:763313658
1481 1481 c, t dbSNP:149671826
1485 1485 c, t dbSNP:184035890
1488 1488 c, t dbSNP:139437157
1489 1489 a, g dbSNP:371297575
1491 1491 a, c dbSNP:769272352
1492 1492 a, c dbSNP:747443576
1500 1500 c, t dbSNP:61745291
1508 1508 c, t dbSNP:770382134
1513 1513 g, t dbSNP:748973638
1524 1524 c, t dbSNP:143566360
1528 1528 a, c, g, t dbSNP:548981290
1529 1529 a, g dbSNP:752592093
1530 1530 a, g dbSNP:387907414
1531 1531 -, g dbSNP:761918152
1531 1531 a, g, t dbSNP:138008896
1531 1531 -, g dbSNP:772380452
1532 1532 c, t dbSNP:751427421
1541 1541 c, t dbSNP:766586533
1548 1548 a, g dbSNP:763085148
1553 1553 c, t dbSNP:750677498
1554 1554 a, g dbSNP:219780
1557 1557 c, t dbSNP:149733854
1560 1560 c, t dbSNP:554611270
1561 1561 a, g dbSNP:786204841
1575 1575 c, t dbSNP:774161015
1576 1576 a, g dbSNP:768382153
1581 1581 a, c dbSNP:761269316
1582 1582 a, g dbSNP:201218449
1593 1593 c, t dbSNP:770435259
1597 1597 c, g dbSNP:139628442
1598 1598 c, t dbSNP:772699208
1609 1609 c, t dbSNP:769498667
1610 1610 a, c dbSNP:747720793
1617 1617 g, t dbSNP:781087324
1620 1620 a, g dbSNP:754677688
1622 1622 a, g dbSNP:746997205
1631 1631 c, t dbSNP:780070024
1634 1634 c, t dbSNP:758566130
1635 1635 a, g dbSNP:199523516
1637 1637 a, c dbSNP:765378283
1638 1638 a, g dbSNP:114551506
1653 1653 a, g dbSNP:369966830
1694 1694 a, g dbSNP:112112443
1752 1752 a, g dbSNP:150553857
1762 1762 a, g dbSNP:565686905
1797 1797 a, g dbSNP:567389844
1801 1801 -, a dbSNP:547523762
1817 1817 c, t dbSNP:547541223
1821 1821 c, t dbSNP:527363387
1838 1838 a, t dbSNP:746123433
1856 1856 c, g dbSNP:571301747
1864 1864 c, t dbSNP:551351878
1884 1884 a, c, g dbSNP:532695308
1891 1891 c, g dbSNP:377710646
1921 1921 a, g dbSNP:142629054
1922 1922 a, c dbSNP:185515617
1933 1933 -, ggtttt dbSNP:370594336
1934 1934 g, t dbSNP:201508874

Target ORF information:

RefSeq Version NM_144492
Organism Homo sapiens (human)
Definition Homo sapiens claudin 14 (CLDN14), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_144492

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
ATGGCCAGCA CGGCCGTGCA GCTTCTGGGC TTCCTGCTCA GCTTCCTGGG CATGGTGGGC 
ACGTTGATCA CCACCATCCT GCCGCACTGG CGGAGGACAG CGCACGTGGG CACCAACATC
CTCACGGCCG TGTCCTACCT GAAAGGGCTC TGGATGGAGT GTGTGTGGCA CAGCACAGGC
ATCTACCAGT GCCAGATCTA CCGATCCCTG CTGGCGCTGC CCCAAGACCT CCAGGCTGCC
CGCGCCCTCA TGGTCATCTC CTGCCTGCTC TCGGGCATAG CCTGCGCCTG CGCCGTCATC
GGGATGAAGT GCACGCGCTG CGCCAAGGGC ACACCCGCCA AGACCACCTT TGCCATCCTC
GGCGGCACCC TCTTCATCCT GGCCGGCCTC CTGTGCATGG TGGCCGTCTC CTGGACCACC
AACGACGTGG TGCAGAACTT CTACAACCCG CTGCTGCCCA GCGGCATGAA GTTTGAGATT
GGCCAGGCCC TGTACCTGGG CTTCATCTCC TCGTCCCTCT CGCTCATTGG TGGCACCCTG
CTTTGCCTGT CCTGCCAGGA CGAGGCACCC TACAGGCCCT ACCAGGCCCC GCCCAGGGCC
ACCACGACCA CTGCAAACAC CGCACCTGCC TACCAGCCAC CAGCTGCCTA CAAAGACAAT
CGGGCCCCCT CAGTGACCTC GGCCACGCAC AGCGGGTACA GGCTGAACGA CTACGTGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu20415
Accession Version NM_001146079.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 720bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product claudin-14
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AY355348.1, AP000695.1 and BC012126.1. Summary: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. The encoded protein also binds specifically to the WW domain of Yes-associated protein. Defects in this gene are the cause of an autosomal recessive form of nonsyndromic sensorineural deafness. It is also reported that four synonymous variants in this gene are associated with kidney stones and reduced bone mineral density. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jun 2010]. Transcript Variant: This variant (beta) differs in the 5' UTR compared to variant 1. All five variants encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY355348.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145122, SAMEA2155590 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
ATGGCCAGCA CGGCCGTGCA GCTTCTGGGC TTCCTGCTCA GCTTCCTGGG CATGGTGGGC 
ACGTTGATCA CCACCATCCT GCCGCACTGG CGGAGGACAG CGCACGTGGG CACCAACATC
CTCACGGCCG TGTCCTACCT GAAAGGGCTC TGGATGGAGT GTGTGTGGCA CAGCACAGGC
ATCTACCAGT GCCAGATCTA CCGATCCCTG CTGGCGCTGC CCCAAGACCT CCAGGCTGCC
CGCGCCCTCA TGGTCATCTC CTGCCTGCTC TCGGGCATAG CCTGCGCCTG CGCCGTCATC
GGGATGAAGT GCACGCGCTG CGCCAAGGGC ACACCCGCCA AGACCACCTT TGCCATCCTC
GGCGGCACCC TCTTCATCCT GGCCGGCCTC CTGTGCATGG TGGCCGTCTC CTGGACCACC
AACGACGTGG TGCAGAACTT CTACAACCCG CTGCTGCCCA GCGGCATGAA GTTTGAGATT
GGCCAGGCCC TGTACCTGGG CTTCATCTCC TCGTCCCTCT CGCTCATTGG TGGCACCCTG
CTTTGCCTGT CCTGCCAGGA CGAGGCACCC TACAGGCCCT ACCAGGCCCC GCCCAGGGCC
ACCACGACCA CTGCAAACAC CGCACCTGCC TACCAGCCAC CAGCTGCCTA CAAAGACAAT
CGGGCCCCCT CAGTGACCTC GGCCACGCAC AGCGGGTACA GGCTGAACGA CTACGTGTGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_001139551.1
CDS678..1397
Misc Feature(1)660..662(+)
Misc Feature(2)699..761(+)
Misc Feature(3)744..1220(+)
Misc Feature(4)921..983(+)
Misc Feature(5)1023..1085(+)
Misc Feature(6)1164..1226(+)
Exon (1)1..596
Gene:CLDN14
Gene Synonym:
Exon (2)597..1752
Gene:CLDN14
Gene Synonym:
Translation
Position Chain Variation Link
1 1 c, t dbSNP:553132355
23 23 -, gga dbSNP:139003220
48 48 g, t dbSNP:375811545
55 55 a, g dbSNP:528517263
146 146 c, t dbSNP:559813058
147 147 a, g dbSNP:372584176
153 153 c, g dbSNP:116629563
199 199 c, t dbSNP:376942377
233 233 a, g dbSNP:557217395
242 242 a, g dbSNP:543253636
274 274 a, t dbSNP:370189669
282 282 c, t dbSNP:574250923
288 288 a, g dbSNP:150344346
341 341 c, g dbSNP:117804848
347 347 -, t dbSNP:758408442
370 370 c, t dbSNP:778118245
381 381 a, g dbSNP:140333712
388 388 a, g dbSNP:219742
414 414 c, g dbSNP:188733
436 436 c, t dbSNP:78291168
437 437 a, g dbSNP:551215354
439 439 c, t dbSNP:369614226
448 448 a, g dbSNP:151272065
483 483 c, t dbSNP:548778387
487 487 a, g dbSNP:528630078
492 492 a, g dbSNP:181645276
495 495 c, t dbSNP:376974087
508 508 a, g dbSNP:552336543
534 534 c, t dbSNP:754434925
541 541 c, t dbSNP:372217521
547 547 c, t dbSNP:114492024
548 548 a, g dbSNP:537704763
583 583 a, g dbSNP:563441963
602 602 c, t dbSNP:557122405
603 603 a, g, t dbSNP:537529014
620 620 c, t dbSNP:759652223
621 621 a, g dbSNP:188479887
625 625 g, t dbSNP:548165835
632 632 a, g dbSNP:779699092
641 641 a, g dbSNP:149049781
652 652 a, g dbSNP:758426367
653 653 c, g dbSNP:750364874
673 673 a, g dbSNP:368231049
687 687 a, g dbSNP:374578221
688 688 c, t dbSNP:113831133
689 689 a, g dbSNP:764358289
692 692 c, t dbSNP:387907416
693 693 a, g dbSNP:202117396
695 695 a, g dbSNP:387907417
705 705 c, g dbSNP:772295911
728 728 c, t dbSNP:150040476
729 729 a, g dbSNP:369883669
732 732 g, t dbSNP:769320772
737 737 c, t dbSNP:387907415
739 739 c, t dbSNP:532176130
740 740 a, g dbSNP:117560775
741 741 -, ttg dbSNP:762948927
744 744 a, c dbSNP:780834768
745 745 c, t dbSNP:768411939
749 749 c, t dbSNP:549639383
751 751 c, t dbSNP:779937857
759 759 c, t dbSNP:758081638
760 760 c, t dbSNP:727504989
761 761 a, g dbSNP:778927942
768 768 c, t dbSNP:757426764
778 778 a, c dbSNP:754032374
779 779 a, g dbSNP:146395322
782 782 c, t dbSNP:560763542
783 783 a, g, t dbSNP:142205038
786 786 a, g dbSNP:759850341
793 793 -, aca dbSNP:752639706
802 802 c, t dbSNP:533194857
803 803 a, g dbSNP:140177046
806 806 c, t dbSNP:150731625
807 807 a, g dbSNP:141139613
836 836 a, g dbSNP:768019537
839 839 c, t dbSNP:746698259
841 841 c, t dbSNP:752960573
844 844 -, gg dbSNP:765103185
844 844 a, g dbSNP:371100799
846 846 c, t dbSNP:745601274
848 848 c, t dbSNP:778842030
858 858 a, t dbSNP:757334760
862 862 a, g dbSNP:148223897
872 872 a, g dbSNP:777960789
872 872 -, g dbSNP:760769965
880 880 a, g dbSNP:756095919
885 885 c, g dbSNP:752992781
886 886 g, t dbSNP:767565332
888 888 c, t dbSNP:755346413
892 892 c, t dbSNP:573588226
893 893 a, g dbSNP:370315827
895 895 a, t dbSNP:763489263
900 900 c, t dbSNP:560052879
905 905 c, t dbSNP:763692550
911 911 c, g dbSNP:760039736
916 916 c, t dbSNP:775222236
918 918 c, t dbSNP:143628692
919 919 a, g dbSNP:368027306
920 920 c, t dbSNP:219779
930 930 g, t dbSNP:770829440
931 931 a, t dbSNP:74315437
937 937 c, g dbSNP:777529810
939 939 c, t dbSNP:756218341
944 944 g, t dbSNP:748115585
945 945 c, g dbSNP:781318012
950 950 a, g dbSNP:577393948
953 953 c, g dbSNP:751747842
954 954 a, t dbSNP:780444223
957 957 c, g dbSNP:758724049
962 962 c, t dbSNP:750946312
963 963 a, g dbSNP:765605373
964 964 c, t dbSNP:762368755
968 968 a, c, t dbSNP:767108790
969 969 a, g dbSNP:759313432
971 971 -, tgcgcc dbSNP:773126341
971 971 c, t dbSNP:374400022
972 972 a, g dbSNP:371106978
976 976 c, t dbSNP:557513586
977 977 c, t dbSNP:113350364
978 978 a, g dbSNP:74315438
991 991 c, t dbSNP:748110915
992 992 a, g dbSNP:781167430
993 993 c, t dbSNP:140257182
994 994 a, g dbSNP:747254086
998 998 c, t dbSNP:764548516
999 999 a, g dbSNP:377019596
1000 1000 c, t dbSNP:373823945
1012 1012 a, c, t dbSNP:555911451
1013 1013 c, g, t dbSNP:754350037
1014 1014 a, c, g dbSNP:138631461
1024 1024 a, c, t dbSNP:370342285
1029 1029 a, c, g dbSNP:377333347
1038 1038 a, g dbSNP:150201704
1040 1040 c, t dbSNP:763411863
1041 1041 a, g dbSNP:769599110
1046 1046 a, c, t dbSNP:727502938
1052 1052 c, t dbSNP:768728088
1056 1056 c, t dbSNP:747033624
1061 1061 c, t dbSNP:780095902
1062 1062 a, g dbSNP:772250957
1064 1064 c, t dbSNP:558404405
1069 1069 c, t dbSNP:373777126
1074 1074 a, g dbSNP:757597772
1075 1075 -, t dbSNP:786200885
1083 1083 a, g dbSNP:140918123
1090 1090 a, g dbSNP:151069240
1091 1091 a, g dbSNP:142846225
1096 1096 c, t dbSNP:754545220
1099 1099 a, c dbSNP:751170450
1100 1100 a, c, t dbSNP:758024791
1101 1101 a, g dbSNP:146755542
1103 1103 c, t dbSNP:140671150
1104 1104 a, c, g dbSNP:776564488
1107 1107 a, g dbSNP:764077250
1121 1121 c, t dbSNP:549938800
1126 1126 c, t dbSNP:775588286
1127 1127 a, g, t dbSNP:746102559
1136 1136 c, t dbSNP:774596862
1139 1139 c, t dbSNP:771208295
1140 1140 a, g dbSNP:749603296
1148 1148 a, g dbSNP:146860442
1156 1156 c, t dbSNP:756749130
1165 1165 c, t dbSNP:143797113
1166 1166 c, g dbSNP:779757519
1172 1172 c, t dbSNP:373672296
1176 1176 a, g dbSNP:377158611
1189 1189 a, c, t dbSNP:75617474
1190 1190 a, c, g dbSNP:756847536
1198 1198 c, t dbSNP:140196815
1199 1199 a, g dbSNP:763846537
1200 1200 c, t dbSNP:760657763
1202 1202 c, t dbSNP:373226526
1203 1203 a, g dbSNP:767528825
1212 1212 a, g dbSNP:759597838
1216 1216 c, t dbSNP:774446882
1217 1217 a, g dbSNP:369688436
1220 1220 g, t dbSNP:749515217
1228 1228 c, t dbSNP:773749542
1233 1233 c, g dbSNP:770259212
1236 1236 g, t dbSNP:375904468
1238 1238 a, c, t dbSNP:771486433
1239 1239 a, g dbSNP:745441972
1245 1245 c, t dbSNP:778283119
1249 1249 a, g dbSNP:755393537
1257 1257 c, t dbSNP:372105353
1264 1264 c, t dbSNP:200651246
1265 1265 a, c, g dbSNP:144371384
1267 1267 c, t dbSNP:374682296
1268 1268 a, g dbSNP:374840285
1280 1280 a, c dbSNP:760219487
1282 1282 c, t dbSNP:564851292
1283 1283 a, g dbSNP:763313658
1291 1291 c, t dbSNP:149671826
1295 1295 c, t dbSNP:184035890
1298 1298 c, t dbSNP:139437157
1299 1299 a, g dbSNP:371297575
1301 1301 a, c dbSNP:769272352
1302 1302 a, c dbSNP:747443576
1310 1310 c, t dbSNP:61745291
1318 1318 c, t dbSNP:770382134
1323 1323 g, t dbSNP:748973638
1334 1334 c, t dbSNP:143566360
1338 1338 a, c, g, t dbSNP:548981290
1339 1339 a, g dbSNP:752592093
1340 1340 a, g dbSNP:387907414
1341 1341 -, g dbSNP:761918152
1341 1341 a, g, t dbSNP:138008896
1341 1341 -, g dbSNP:772380452
1342 1342 c, t dbSNP:751427421
1351 1351 c, t dbSNP:766586533
1358 1358 a, g dbSNP:763085148
1363 1363 c, t dbSNP:750677498
1364 1364 a, g dbSNP:219780
1367 1367 c, t dbSNP:149733854
1370 1370 c, t dbSNP:554611270
1371 1371 a, g dbSNP:786204841
1385 1385 c, t dbSNP:774161015
1386 1386 a, g dbSNP:768382153
1391 1391 a, c dbSNP:761269316
1392 1392 a, g dbSNP:201218449
1403 1403 c, t dbSNP:770435259
1407 1407 c, g dbSNP:139628442
1408 1408 c, t dbSNP:772699208
1419 1419 c, t dbSNP:769498667
1420 1420 a, c dbSNP:747720793
1427 1427 g, t dbSNP:781087324
1430 1430 a, g dbSNP:754677688
1432 1432 a, g dbSNP:746997205
1441 1441 c, t dbSNP:780070024
1444 1444 c, t dbSNP:758566130
1445 1445 a, g dbSNP:199523516
1447 1447 a, c dbSNP:765378283
1448 1448 a, g dbSNP:114551506
1463 1463 a, g dbSNP:369966830
1504 1504 a, g dbSNP:112112443
1562 1562 a, g dbSNP:150553857
1572 1572 a, g dbSNP:565686905
1607 1607 a, g dbSNP:567389844
1611 1611 -, a dbSNP:547523762
1627 1627 c, t dbSNP:547541223
1631 1631 c, t dbSNP:527363387
1648 1648 a, t dbSNP:746123433
1666 1666 c, g dbSNP:571301747
1674 1674 c, t dbSNP:551351878
1694 1694 a, c, g dbSNP:532695308
1701 1701 c, g dbSNP:377710646
1731 1731 a, g dbSNP:142629054
1732 1732 a, c dbSNP:185515617
1743 1743 -, ggtttt dbSNP:370594336
1744 1744 g, t dbSNP:201508874

Target ORF information:

RefSeq Version NM_001146079
Organism Homo sapiens (human)
Definition Homo sapiens claudin 14 (CLDN14), transcript variant 5, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001146079

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
ATGGCCAGCA CGGCCGTGCA GCTTCTGGGC TTCCTGCTCA GCTTCCTGGG CATGGTGGGC 
ACGTTGATCA CCACCATCCT GCCGCACTGG CGGAGGACAG CGCACGTGGG CACCAACATC
CTCACGGCCG TGTCCTACCT GAAAGGGCTC TGGATGGAGT GTGTGTGGCA CAGCACAGGC
ATCTACCAGT GCCAGATCTA CCGATCCCTG CTGGCGCTGC CCCAAGACCT CCAGGCTGCC
CGCGCCCTCA TGGTCATCTC CTGCCTGCTC TCGGGCATAG CCTGCGCCTG CGCCGTCATC
GGGATGAAGT GCACGCGCTG CGCCAAGGGC ACACCCGCCA AGACCACCTT TGCCATCCTC
GGCGGCACCC TCTTCATCCT GGCCGGCCTC CTGTGCATGG TGGCCGTCTC CTGGACCACC
AACGACGTGG TGCAGAACTT CTACAACCCG CTGCTGCCCA GCGGCATGAA GTTTGAGATT
GGCCAGGCCC TGTACCTGGG CTTCATCTCC TCGTCCCTCT CGCTCATTGG TGGCACCCTG
CTTTGCCTGT CCTGCCAGGA CGAGGCACCC TACAGGCCCT ACCAGGCCCC GCCCAGGGCC
ACCACGACCA CTGCAAACAC CGCACCTGCC TACCAGCCAC CAGCTGCCTA CAAAGACAAT
CGGGCCCCCT CAGTGACCTC GGCCACGCAC AGCGGGTACA GGCTGAACGA CTACGTGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.