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LEMD3 LEM domain containing 3 [Homo sapiens (human)]

Gene Symbol LEMD3
Entrez Gene ID 23592
Full Name LEM domain containing 3
Synonyms MAN1
General protein information
Preferred Names
inner nuclear membrane protein Man1
Names
inner nuclear membrane protein Man1
LEM domain-containing protein 3
integral inner nuclear membrane protein
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

12

12q14

Summary This locus encodes a LEM domain-containing protein. The encoded protein functions to antagonize transforming growth factor-beta signaling at the inner nuclear membrane. Two transcript variants encoding different isoforms have been found for this gene. Mutations in this gene have been associated with osteopoikilosis, Buschke-Ollendorff syndrome and melorheostosis.[provided by RefSeq, Nov 2009]. lac of sum
Disorder MIM:

607844

Disorder Html: Osteopoikilosis, 166700 (3); Buschke-Ollendorff syndrome, 166700 (3);





The following LEMD3 gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the LEMD3 gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu19032 NM_014319 Homo sapiens LEM domain containing 3 (LEMD3), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD Quote Price
OHu04065 NM_001167614 Homo sapiens LEM domain containing 3 (LEMD3), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD Quote Price

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu19032
Accession Version NM_014319.4
Sequence Information ORF Nucleotide Sequence (Length: 2736bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product inner nuclear membrane protein Man1 isoform 1
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK312473.1, AF112299.2 and BX390128.2. This sequence is a reference standard in the RefSeqGene project. On Nov 10, 2009 this sequence version replaced gi:36287116. Summary: This locus encodes a LEM domain-containing protein. The encoded protein functions to antagonize transforming growth factor-beta signaling at the inner nuclear membrane. Two transcript variants encoding different isoforms have been found for this gene. Mutations in this gene have been associated with osteopoikilosis, Buschke-Ollendorff syndrome and melorheostosis.[provided by RefSeq, Nov 2009]. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF112299.2, AK024954.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
ATGGCGGCGG CAGCAGCTTC GGCGCCTCAG CAGCTCTCGG ATGAGGAGCT TTTCTCTCAG 
CTCCGCCGTT ACGGCCTGTC TCCCGGACCA GTGACGGAGA GCACCCGCCC GGTCTACCTC
AAGAAGCTGA AGAAGCTTCG AGAGGAAGAG CAGCAACAGC ACCGGTCAGG GGGCCGCGGC
AACAAGACGC GGAACAGTAA TAACAATAAC ACGGCAGCCG CCACGGTCGC AGCCGCGGGA
CCAGCGGCGG CGGCGGCCGC GGGGATGGGG GTCCGGCCGG TCTCGGGCGA CCTCTCCTAC
TTACGGACTC CTGGGGGCCT GTGCCGAATC TCGGCCTCTG GCCCAGAGAG CCTCCTGGGA
GGGCCCGGGG GCGCCTCCGC CGCCCCCGCG GCTGGCAGCA AAGTGCTGCT GGGCTTCAGC
TCGGACGAGT CGGACGTGGA GGCCAGTCCC CGGGACCAGG CCGGCGGCGG CGGGAGGAAA
GACCGGGCTT CGCTCCAGTA CCGCGGGCTC AAAGCGCCGC CGGCGCCCCT GGCCGCCAGC
GAGGTGACTA ACAGCAACTC TGCAGAGCGA AGGAAGCCCC ACTCGTGGTG GGGGGCCAGG
AGGCCGGCGG GCCCCGAGCT GCAGACCCCG CCGGGGAAAG ATGGAGCAGT GGAGGACGAG
GAAGGGGAGG GAGAGGACGG TGAGGAGAGG GACCCGGAGA CCGAGGAGCC GCTCTGGGCG
AGCCGGACCG TGAATGGCAG CCGGCTTGTC CCCTACAGCT GCCGGGAAAA CTATTCGGAC
TCAGAGGAAG AGGACGACGA CGACGTGGCC TCCAGCAGAC AGGTATTAAA GGACGACTCC
CTTTCCCGGC ATCGGCCCAG ACGAACCCAT AGTAAGCCTC TCCCCCCGCT GACTGCTAAA
TCGGCCGGCG GCAGGCTGGA GACTTCAGTT CAGGGAGGGG GAGGACTCGC GATGAATGAC
AGGGCGGCGG CTGCCGGGAG TCTAGACAGG AGCCGAAACC TCGAAGAGGC GGCGGCCGCG
GAGCAGGGAG GAGGGTGTGA TCAAGTGGAC TCCAGCCCCG TTCCTAGATA CCGTGTTAAC
GCTAAGAAAC TGACCCCTCT CCTGCCCCCG CCACTTACTG ACATGGACTC AACCTTGGAT
TCGTCAACAG GCTCCCTTCT GAAAACCAAT AATCATATTG GCGGTGGGGC CTTCAGTGTG
GACTCCCCCA GGATTTATTC TAACAGTCTC CCTCCCAGTG CGGCGGTGGC CGCCTCTAGT
TCACTCAGGA TCAATCACGC CAATCATACG GGCTCCAATC ATACCTACCT GAAAAACACA
TACAACAAAC CGAAGCTTTC CGAACCCGAA GAGGAACTTC TCCAGCAATT TAAACGGGAG
GAGGTGTCCC CAACAGGGAG TTTCAGTGCC CACTACTTGT CGATGTTTCT CTTAACTGCT
GCCTGCTTAT TTTTCCTAAT ACTGGGACTG ACTTACCTAG GAATGAGAGG GACAGGAGTA
TCTGAGGATG GAGAACTCAG CATAGAAAAC CCCTTTGGTG AAACATTTGG AAAAATACAA
GAAAGTGAAA AAACTCTTAT GATGAACACA TTATATAAGC TTCATGATCG ATTGGCACAG
CTTGCAGGAG ATCATGAATG TGGCAGTTCT AGTCAAAGAA CGCTTTCTGT TCAAGAGGCA
GCTGCGTATT TAAAAGATTT AGGTCCTGAA TATGAAGGTA TATTTAACAC TTCATTGCAG
TGGATCTTAG AAAATGGAAA AGATGTTGGA ATAAGGTGTG TTGGTTTTGG CCCTGAGGAA
GAATTGACAA ATATAACTGA TGTGCAGTTT TTACAGTCCA CAAGACCACT GATGTCTTTT
TGGTGTCGTT TTCGACGTGC TTTTGTTACT GTAACTCACA GATTATTGTT GTTATGCTTA
GGTGTAGTGA TGGTTTGTGT CGTTCTGCGT TACATGAAAT ATCGATGGAC AAAAGAAGAG
GAGGAAACAA GGCAGATGTA TGATATGGTG GTAAAGATTA TAGATGTTTT ACGAAGTCAT
AATGAAGCCT GCCAGGAAAA CAAAGATTTA CAACCTTACA TGCCTATTCC ACATGTACGC
GATTCCTTAA TACAGCCTCA TGACAGGAAA AAAATGAAGA AAGTCTGGGA TAGAGCTGTT
GACTTCCTTG CTGCTAATGA GTCTAGAGTT CGCACGGAAA CACGAAGAAT AGGTGGTGCA
GATTTTCTGG TTTGGCGGTG GATCCAGCCT TCTGCATCCT GTGACAAAAT ATTAGTTATA
CCTTCTAAAG TATGGCAAGG TCAAGCATTT CATTTAGATA GAAGAAATTC ACCACCAAAT
AGTTTGACAC CGTGTCTAAA GATTCGGAAT ATGTTTGATC CCGTTATGGA AATAGGGGAT
CAGTGGCATT TGGCAATTCA AGAAGCAATT TTAGAAAAAT GCAGTGATAA TGATGGCATT
GTTCACATTG CAGTAGACAA AAATTCACGT GAGGGTTGTG TATATGTTAA ATGTCTGTCT
CCAGAATATG CTGGAAAGGC TTTTAAAGCA TTGCATGGCT CTTGGTTTGA TGGGAAATTG
GTTACAGTAA AATATTTACG ACTAGATAGA TACCACCATC GCTTTCCCCA GGCTCTCACT
TCCAACACTC CATTGAAGCC ATCAAATAAA CATATGAACT CCATGTCTCA TCTTCGTCTT
CGGACTGGCC TAACCAATTC TCAAGGAAGT TCCTGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_055134.2
CDS27..2762
Misc Feature(1)30..32(+)
Misc Feature(2)51..179(+)
Misc Feature(3)105..152(+)
Misc Feature(4)444..446(+)
Misc Feature(5)447..449(+)
Misc Feature(6)456..458(+)
Misc Feature(7)579..581(+)
Misc Feature(8)585..587(+)
Misc Feature(9)801..803(+)
Misc Feature(10)807..809(+)
Misc Feature(11)864..866(+)
Misc Feature(12)1080..1082(+)
Misc Feature(13)1119..1121(+)
Misc Feature(14)1230..1232(+)
Misc Feature(15)1449..1511(+)
Misc Feature(16)1452..2279(+)
Misc Feature(17)1908..1970(+)
Misc Feature(18)2121..2759(+)
Misc Feature(19)2355..2357(+)
Misc Feature(20)2379..2654(+)
Misc Feature(21)2673..2675(+)
Misc Feature(22)2757..2759(+)
Exon (1)1..1548
Gene:LEMD3
Gene Synonym:
Exon (2)1549..1586
Gene:LEMD3
Gene Synonym:
Exon (3)1587..1653
Gene:LEMD3
Gene Synonym:
Exon (4)1654..1721
Gene:LEMD3
Gene Synonym:
Exon (5)1722..1801
Gene:LEMD3
Gene Synonym:
Exon (6)1802..1947
Gene:LEMD3
Gene Synonym:
Exon (7)1948..2049
Gene:LEMD3
Gene Synonym:
Exon (8)2050..2152
Gene:LEMD3
Gene Synonym:
Exon (9)2153..2331
Gene:LEMD3
Gene Synonym:
Exon (10)2332..2413
Gene:LEMD3
Gene Synonym:
Exon (11)2414..2519
Gene:LEMD3
Gene Synonym:
Exon (12)2520..2598
Gene:LEMD3
Gene Synonym:
Exon (13)2599..4798
Gene:LEMD3
Gene Synonym:
Translation
Position Chain Variation Link
3 3 c, t dbSNP:779239307
4 4 c, t dbSNP:778401685
7 7 -, a dbSNP:752092179
12 12 c, g dbSNP:540958232
14 14 c, g, t dbSNP:758146972
15 15 c, t dbSNP:746522089
16 16 c, g, t dbSNP:560983978
17 17 c, t dbSNP:776776070
21 21 a, g dbSNP:747864180
28 28 -, ggc dbSNP:759986057
30 30 g, t dbSNP:769677064
34 34 c, t dbSNP:772903185
35 35 a, g dbSNP:763192267
39 39 a, g dbSNP:766588987
43 43 c, t dbSNP:774353434
44 44 c, t dbSNP:759674593
46 46 c, g, t dbSNP:768011921
48 48 a, g dbSNP:756414909
59 59 g, t dbSNP:764473245
60 60 c, t dbSNP:369764718
65 65 a, g dbSNP:373288363
66 66 a, g dbSNP:779865961
72 72 a, g dbSNP:746513740
80 80 c, g dbSNP:377077013
82 82 c, t dbSNP:780968500
84 84 c, g dbSNP:748067865
86 86 g, t dbSNP:769647254
87 87 c, t dbSNP:529619321
90 90 c, g dbSNP:749045900
91 91 c, g dbSNP:771132420
93 93 c, t dbSNP:774626762
98 98 c, t dbSNP:549481418
101 101 c, t dbSNP:767635681
104 104 a, g dbSNP:548059711
113 113 a, g dbSNP:775456269
119 119 a, g dbSNP:761206230
121 121 c, t dbSNP:201950187
125 125 a, g dbSNP:754174270
128 128 a, c dbSNP:762333553
136 136 c, g dbSNP:766098043
137 137 a, g dbSNP:569384904
144 144 c, t dbSNP:754698589
146 146 c, t dbSNP:780709633
152 152 a, g dbSNP:752150192
166 166 c, g dbSNP:756017417
185 185 a, g dbSNP:777625988
188 188 c, t dbSNP:150212307
189 189 c, g dbSNP:531792416
191 191 c, g dbSNP:138821698
201 201 c, t dbSNP:746044253
202 202 a, g dbSNP:772216122
204 204 a, g dbSNP:775574495
206 206 c, t dbSNP:760683855
211 211 a, c dbSNP:769194295
215 215 a, g dbSNP:777043878
218 218 a, g dbSNP:762245557
223 223 a, g dbSNP:765645790
225 225 a, c dbSNP:551911988
227 227 a, t dbSNP:750847187
228 228 -, aac dbSNP:767735305
231 231 a, g dbSNP:759189662
238 238 c, g dbSNP:767085294
239 239 a, g dbSNP:752234472
248 248 c, t dbSNP:755651275
250 250 a, c dbSNP:777739111
260 260 c, g dbSNP:753825048
265 265 c, g dbSNP:757211962
267 267 c, g dbSNP:778640480
268 268 c, g dbSNP:745669202
271 271 c, t dbSNP:772279938
289 289 a, g dbSNP:780199936
296 296 g, t dbSNP:747079226
318 318 c, t dbSNP:571742271
325 325 a, t dbSNP:768667554
347 347 a, g dbSNP:776870950
356 356 c, t dbSNP:534560505
362 362 c, t dbSNP:61736594
371 371 a, g dbSNP:530591432
377 377 c, t dbSNP:773651512
404 404 c, t dbSNP:61736593
409 409 c, t dbSNP:767190888
488 488 -, cgg dbSNP:750001959
541 541 a, c, t dbSNP:775048974
547 547 c, t dbSNP:536611944
559 559 c, t dbSNP:556713896
563 563 c, t dbSNP:753380295
570 570 g, t dbSNP:757121957
572 572 a, g dbSNP:576557496
574 574 -, t dbSNP:757886688
580 580 a, g dbSNP:750206660
581 581 c, t dbSNP:765520773
583 583 a, g dbSNP:758194466
594 594 c, g dbSNP:780300500
619 619 a, g dbSNP:201695195
634 634 a, c, t dbSNP:755257962
638 638 c, g dbSNP:748249096
644 644 a, g dbSNP:770408327
656 656 a, g dbSNP:773919248
659 659 c, g dbSNP:749637412
662 662 a, g dbSNP:771253349
666 666 g, t dbSNP:774803333
667 667 a, g dbSNP:760207766
675 675 c, g dbSNP:763742183
680 680 c, g dbSNP:558755661
687 687 c, g dbSNP:904411
692 692 a, g dbSNP:761371155
711 711 c, g dbSNP:765156027
719 719 c, t dbSNP:750409065
721 721 c, t dbSNP:758383183
722 722 a, g dbSNP:766047049
730 730 a, g dbSNP:751372115
735 735 c, t dbSNP:755095379
749 749 c, g dbSNP:781619701
755 755 c, g dbSNP:752878753
756 756 g, t dbSNP:748230618
763 763 a, g dbSNP:756299363
768 768 c, t dbSNP:778406683
770 770 g, t dbSNP:749713372
775 775 c, t dbSNP:771503173
776 776 c, g, t dbSNP:148964879
778 778 c, t dbSNP:768286122
779 779 a, c, t dbSNP:201160057
788 788 c, t dbSNP:769244916
789 789 c, t dbSNP:772810730
802 802 c, t dbSNP:762730876
804 804 g, t dbSNP:7487311
812 812 a, g dbSNP:766352719
815 815 a, g dbSNP:751296569
818 818 -, gac dbSNP:780012432
820 820 a, t dbSNP:759468776
825 825 c, g dbSNP:550697467
830 830 c, g dbSNP:541345339
835 835 c, t dbSNP:147082719
836 836 c, t dbSNP:756430180
839 839 c, t dbSNP:777964422
847 847 a, g dbSNP:561008904
860 860 c, t dbSNP:200222837
861 861 c, g dbSNP:376432823
865 865 c, t dbSNP:746216854
867 867 c, g dbSNP:747025576
873 873 -, cggcat dbSNP:746915404
873 873 a, c dbSNP:780417676
874 874 a, g dbSNP:747757104
883 883 c, g dbSNP:769441217
884 884 c, t dbSNP:138509307
887 887 a, c, g dbSNP:772538120
888 888 c, g dbSNP:144086377
891 891 a, g dbSNP:774384614
892 892 c, t dbSNP:769786244
896 896 c, t dbSNP:147328826
897 897 a, g dbSNP:551179499
903 903 c, g dbSNP:752572923
906 906 c, g dbSNP:760918161
908 908 -, c dbSNP:768525907
908 908 c, t dbSNP:764393737
909 909 c, t dbSNP:753850539
912 912 a, c, g dbSNP:757425587
913 913 c, g dbSNP:750988811
914 914 a, g, t dbSNP:758934476
919 919 c, t dbSNP:199824717
920 920 c, t dbSNP:755750425
930 930 g, t dbSNP:374194981
932 932 c, t dbSNP:376059733
933 933 g, t dbSNP:35221558
936 936 g, t dbSNP:551985147
939 939 a, g dbSNP:200784504
941 941 c, g dbSNP:745762772
954 954 g, t dbSNP:772145338
956 956 g, t dbSNP:775371062
961 961 a, g dbSNP:760605681
963 963 c, g, t dbSNP:200070970
964 964 c, g, t dbSNP:201615997
967 967 g, t dbSNP:750504733
969 969 c, g dbSNP:201228238
974 974 c, t dbSNP:183253527
976 976 c, g dbSNP:567928632
979 979 c, t dbSNP:199902847
986 986 c, g dbSNP:372553791
990 990 a, g dbSNP:755407121
991 991 c, t dbSNP:777266847
994 994 c, t dbSNP:748918240
995 995 a, g dbSNP:756894525
1001 1001 a, c, g, t dbSNP:375580551
1003 1003 a, g dbSNP:775636778
1009 1009 c, t dbSNP:746769484
1014 1014 a, t dbSNP:768546772
1026 1026 a, c, g dbSNP:147262660
1028 1028 c, g dbSNP:765389652
1033 1033 -, ggc dbSNP:780794872
1034 1034 a, g dbSNP:773266350
1039 1039 c, g, t dbSNP:150526974
1043 1043 c, g dbSNP:752106074
1044 1044 a, g dbSNP:755459590
1048 1048 a, t dbSNP:767880318
1049 1049 a, g dbSNP:753010858
1062 1062 g, t dbSNP:756879696
1085 1085 a, c, g dbSNP:770601096
1086 1086 a, c, g dbSNP:758022128
1089 1089 c, t dbSNP:202161021
1101 1101 a, g dbSNP:376822761
1104 1104 a, c dbSNP:780981110
1120 1120 c, t dbSNP:747950441
1123 1123 c, g, t dbSNP:199884145
1124 1124 c, t dbSNP:762994114
1125 1125 c, t dbSNP:139507581
1129 1129 c, t dbSNP:202245561
1131 1131 c, t dbSNP:371098833
1133 1133 c, g dbSNP:767925680
1134 1134 a, c dbSNP:200288324
1135 1135 c, t dbSNP:201542546
1146 1146 c, g dbSNP:764953197
1151 1151 a, g dbSNP:750150042
1152 1152 g, t dbSNP:758148747
1161 1161 c, t dbSNP:368502571
1171 1171 c, t dbSNP:751043353
1173 1173 a, g dbSNP:143295477
1180 1180 c, t dbSNP:372588607
1182 1182 c, t dbSNP:554852726
1185 1185 c, g, t dbSNP:146241425
1194 1194 a, g dbSNP:749468914
1195 1195 a, g dbSNP:771144409
1200 1200 c, t dbSNP:774359633
1202 1202 c, t dbSNP:759594603
1204 1204 c, t dbSNP:367612390
1211 1211 c, g, t dbSNP:775902004
1220 1220 a, c dbSNP:372402033
1221 1221 a, g dbSNP:754287790
1228 1228 a, t dbSNP:759247239
1231 1231 c, t dbSNP:139346096
1243 1243 -, attcta dbSNP:748410937
1257 1257 c, t dbSNP:766191006
1261 1261 c, g dbSNP:751075559
1269 1269 c, g dbSNP:754487253
1276 1276 c, t dbSNP:199605857
1284 1284 a, g dbSNP:752524303
1295 1295 g, t dbSNP:756074055
1296 1296 a, g dbSNP:201129667
1297 1297 a, t dbSNP:777476143
1300 1300 a, g dbSNP:562992922
1309 1309 a, g dbSNP:749097407
1311 1311 c, t dbSNP:757460816
1321 1321 c, t dbSNP:779074454
1324 1324 a, g dbSNP:745933801
1330 1330 a, c dbSNP:768302841
1338 1338 a, g dbSNP:775662292
1345 1345 a, c dbSNP:747480471
1356 1356 c, g dbSNP:144127577
1357 1357 c, t dbSNP:569480939
1366 1366 c, g dbSNP:762333334
1367 1367 c, t dbSNP:766097829
1371 1371 c, t dbSNP:371748000
1376 1376 a, g dbSNP:145116568
1381 1381 -, a dbSNP:756668294
1381 1381 a, g dbSNP:766893227
1419 1419 a, g dbSNP:376067130
1422 1422 a, g dbSNP:755984431
1423 1423 a, g dbSNP:764079361
1425 1425 a, g, t dbSNP:199915804
1453 1453 g, t dbSNP:371901972
1457 1457 c, t dbSNP:547625447
1462 1462 c, g, t dbSNP:200415494
1463 1463 g, t dbSNP:149129862
1464 1464 a, g dbSNP:758680061
1469 1469 a, c dbSNP:779934044
1475 1475 a, g dbSNP:747141497
1487 1487 a, g dbSNP:769281226
1491 1491 a, g, t dbSNP:777316626
1495 1495 g, t dbSNP:770000098
1514 1514 a, g dbSNP:773654384
1516 1516 a, g dbSNP:759040154
1524 1524 g, t dbSNP:142265837
1529 1529 a, t dbSNP:774970317
1534 1534 a, g dbSNP:760247162
1540 1540 a, g dbSNP:375079599
1550 1550 a, g dbSNP:566688579
1556 1556 a, c, t dbSNP:749717670
1560 1560 g, t dbSNP:369113542
1572 1572 -, ttggaa dbSNP:759909210
1573 1573 g, t dbSNP:760159217
1590 1590 a, c dbSNP:779276438
1597 1597 a, c dbSNP:746625092
1612 1612 a, g dbSNP:151256200
1621 1621 a, g dbSNP:776062606
1636 1636 a, g dbSNP:761447049
1646 1646 a, g dbSNP:769585910
1657 1657 a, c, g dbSNP:774273011
1658 1658 a, t dbSNP:767819719
1670 1670 c, g dbSNP:553028286
1675 1675 c, g dbSNP:760830144
1678 1678 a, g dbSNP:764193615
1685 1685 a, g dbSNP:753873005
1687 1687 c, t dbSNP:188376092
1689 1689 a, c dbSNP:765794322
1693 1693 c, t dbSNP:750784348
1703 1703 g, t dbSNP:758808182
1708 1708 c, t dbSNP:780415646
1711 1711 c, t dbSNP:747793228
1712 1712 a, g dbSNP:755722811
1714 1714 a, g dbSNP:375964932
1731 1731 c, t dbSNP:374655981
1746 1746 a, g dbSNP:374107839
1748 1748 a, g dbSNP:368041039
1754 1754 a, c dbSNP:565217537
1755 1755 a, t dbSNP:745760794
1758 1758 g, t dbSNP:566358684
1761 1761 c, t dbSNP:779844005
1770 1770 a, g dbSNP:371485270
1772 1772 c, t dbSNP:140496862
1773 1773 a, t dbSNP:776761325
1777 1777 a, g dbSNP:762043417
1784 1784 a, g dbSNP:769822113
1788 1788 c, g dbSNP:773280693
1789 1789 a, g dbSNP:112859075
1793 1793 g, t dbSNP:763389434
1802 1802 a, g dbSNP:749967974
1809 1809 a, g dbSNP:758347889
1818 1818 c, t dbSNP:779926136
1830 1830 c, t dbSNP:746792069
1832 1832 c, g dbSNP:768283662
1836 1836 a, g dbSNP:185283829
1840 1840 c, t dbSNP:748299191
1844 1844 c, t dbSNP:770011862
1850 1850 a, g, t dbSNP:372338782
1852 1852 a, g dbSNP:771435908
1853 1853 a, g dbSNP:774767140
1860 1860 a, c dbSNP:760112650
1864 1864 a, c dbSNP:368604047
1874 1874 a, g dbSNP:767735135
1877 1877 c, g dbSNP:776002588
1886 1886 c, t dbSNP:761499461
1893 1893 c, t dbSNP:200189969
1894 1894 a, g dbSNP:765045080
1899 1899 a, c, t dbSNP:749951964
1900 1900 a, g dbSNP:766320286
1903 1903 a, g dbSNP:751409394
1905 1905 a, g dbSNP:376680164
1907 1907 c, t dbSNP:780904042
1918 1918 c, t dbSNP:747990796
1925 1925 c, t dbSNP:200578207
1928 1928 a, g dbSNP:778009960
1941 1941 a, t dbSNP:749363247
1957 1957 c, t dbSNP:754855189
1959 1959 a, g dbSNP:369133002
1967 1967 c, g dbSNP:373040508
1975 1975 a, g dbSNP:202030550
1977 1977 g, t dbSNP:777566184
1982 1982 a, g dbSNP:749433061
1989 1989 c, t dbSNP:267607217
1990 1990 a, g dbSNP:757507566
2006 2006 a, g dbSNP:576862487
2007 2007 a, g dbSNP:374790398
2021 2021 a, g dbSNP:746019192
2032 2032 c, t dbSNP:772706117
2039 2039 a, c dbSNP:780751263
2040 2040 a, g dbSNP:538856716
2041 2041 a, c dbSNP:769095661
2042 2042 g, t dbSNP:777055317
2043 2043 a, t dbSNP:762453236
2045 2045 c, t dbSNP:770671188
2052 2052 a, g dbSNP:769297537
2053 2053 c, t dbSNP:201433608
2057 2057 a, g dbSNP:748609383
2059 2059 a, c, g dbSNP:770458284
2065 2065 a, g dbSNP:200391612
2066 2066 c, t dbSNP:541359325
2068 2068 a, g dbSNP:774986795
2069 2069 c, t dbSNP:760549628
2074 2074 a, c dbSNP:764077258
2082 2082 a, g dbSNP:147072982
2088 2088 a, g dbSNP:761711143
2089 2089 a, g dbSNP:199542833
2095 2095 c, t dbSNP:750611668
2109 2109 c, g dbSNP:758728629
2112 2112 a, g dbSNP:762830732
2117 2117 a, g, t dbSNP:751745237
2118 2118 c, g dbSNP:369198842
2121 2121 c, g dbSNP:781741006
2124 2124 c, t dbSNP:373577886
2125 2125 a, g, t dbSNP:367618543
2126 2126 c, t dbSNP:199712960
2128 2128 a, g dbSNP:370494111
2131 2131 a, c dbSNP:543788718
2133 2133 c, t dbSNP:373975270
2171 2171 a, c, g dbSNP:534883939
2177 2177 c, t dbSNP:758041929
2183 2183 c, t dbSNP:368699453
2194 2194 a, t dbSNP:746504394
2202 2202 a, c dbSNP:768168248
2203 2203 a, g dbSNP:776038819
2209 2209 c, g dbSNP:748053712
2217 2217 c, t dbSNP:769674069
2218 2218 g, t dbSNP:773133991
2221 2221 c, t dbSNP:376437712
2222 2222 a, g dbSNP:138445113
2241 2241 a, g dbSNP:180693560
2254 2254 c, t dbSNP:759706763
2257 2257 c, t dbSNP:767566947
2262 2262 c, t dbSNP:752732536
2268 2268 a, g dbSNP:76293710
2270 2270 c, t dbSNP:764652307
2276 2276 g, t dbSNP:754173455
2284 2284 c, g dbSNP:577090853
2285 2285 c, t dbSNP:757668158
2289 2289 a, g dbSNP:142542896
2290 2290 a, g dbSNP:779192767
2302 2302 -, atctgagg dbSNP:746387692
2304 2304 a, t dbSNP:754595680
2305 2305 c, t dbSNP:546005703
2307 2307 c, t dbSNP:747674456
2321 2321 g, t dbSNP:769735325
2324 2324 a, c, g dbSNP:777903247
2344 2344 a, g dbSNP:750770845
2357 2357 a, c dbSNP:146896083
2361 2361 c, t dbSNP:780743767
2364 2364 a, c dbSNP:752226487
2374 2374 c, t dbSNP:755527292
2378 2378 a, g dbSNP:777455273
2392 2392 a, g dbSNP:749169259
2409 2409 a, g dbSNP:549092592
2412 2412 a, t dbSNP:200170180
2413 2413 c, t dbSNP:745716875
2418 2418 a, t dbSNP:757257470
2419 2419 c, t dbSNP:778755584
2423 2423 g, t dbSNP:138951987
2424 2424 g, t dbSNP:745655839
2437 2437 c, t dbSNP:758081622
2451 2451 a, g dbSNP:779933634
2454 2454 a, g dbSNP:747136567
2461 2461 a, g dbSNP:768883372
2470 2470 a, g dbSNP:776683114
2474 2474 g, t dbSNP:748264298
2475 2475 a, g dbSNP:770259439
2486 2486 g, t dbSNP:199856827
2492 2492 c, t dbSNP:773539826
2497 2497 c, t dbSNP:763543576
2514 2514 c, t dbSNP:766583566
2515 2515 g, t dbSNP:774790837
2520 2520 a, c, g dbSNP:758364295
2522 2522 c, t dbSNP:201325184
2555 2555 c, t dbSNP:755193050
2557 2557 c, g dbSNP:756266770
2560 2560 a, g dbSNP:200089211
2561 2561 a, t dbSNP:748387291
2564 2564 c, g dbSNP:769822240
2580 2580 c, t dbSNP:367781819
2585 2585 c, t dbSNP:371626791
2590 2590 a, g dbSNP:267607216
2596 2596 a, t dbSNP:749698901
2598 2598 -, g dbSNP:767408063
2612 2612 a, g dbSNP:754715782
2622 2622 a, t dbSNP:780993841
2625 2625 c, t dbSNP:376937981
2643 2643 c, t dbSNP:752848029
2644 2644 a, g dbSNP:149439907
2648 2648 c, g dbSNP:143860838
2663 2663 c, t dbSNP:369210837
2671 2671 a, g dbSNP:201986205
2679 2679 c, t dbSNP:371624142
2684 2684 a, g dbSNP:17101179
2687 2687 a, g dbSNP:141624082
2691 2691 a, g dbSNP:146215492
2699 2699 c, t dbSNP:548156782
2706 2706 -, c dbSNP:749531910
2710 2710 c, t dbSNP:772526332
2713 2713 c, t dbSNP:745816602
2715 2715 c, t dbSNP:772006079
2720 2720 -, tcg dbSNP:757484190
2721 2721 c, t dbSNP:201280850
2722 2722 a, g dbSNP:761501582
2727 2727 c, t dbSNP:201930700
2728 2728 a, g dbSNP:376532238
2734 2734 g, t dbSNP:762568799
2735 2735 a, c dbSNP:765824548
2741 2741 c, t dbSNP:139254649
2743 2743 a, g dbSNP:759470441
2750 2750 a, g dbSNP:767239085
2754 2754 a, g dbSNP:752543800
2759 2759 c, t dbSNP:756284214
2766 2766 g, t dbSNP:779756206
2767 2767 a, g dbSNP:753840503
2775 2775 c, t dbSNP:369548419
2776 2776 c, t dbSNP:373665363
2785 2785 a, g dbSNP:779167118
2799 2799 a, g, t dbSNP:374013073
2804 2804 -, aa dbSNP:779188112
2813 2813 a, g dbSNP:376436071
2855 2855 a, g dbSNP:533399241
2891 2891 a, g dbSNP:536443053
2908 2908 a, g dbSNP:746798464
2932 2932 a, g dbSNP:146145624
2960 2960 c, t dbSNP:569925368
2987 2987 a, g dbSNP:139476203
2994 2994 c, t dbSNP:558557521
3009 3009 a, g dbSNP:202237128
3012 3012 a, g dbSNP:572184079
3057 3057 g, t dbSNP:200928805
3077 3077 -, a dbSNP:747017729
3102 3102 g, t dbSNP:188694142
3124 3124 c, t dbSNP:181182810
3162 3162 c, t dbSNP:574201881
3209 3209 c, t dbSNP:768359330
3238 3238 c, t dbSNP:144515474
3249 3249 c, t dbSNP:563052297
3274 3274 a, g dbSNP:375342655
3285 3285 a, g dbSNP:576284776
3294 3294 a, g dbSNP:545023029
3315 3315 a, g dbSNP:183716212
3338 3338 a, g dbSNP:527664684
3354 3354 c, g dbSNP:547604504
3371 3371 c, g dbSNP:769310674
3411 3411 a, g dbSNP:561424277
3417 3417 c, t dbSNP:12302249
3450 3450 c, t dbSNP:188087693
3487 3487 a, g dbSNP:569987408
3507 3507 a, t dbSNP:148427854
3527 3527 g, t dbSNP:199619679
3555 3555 -, agtatt dbSNP:768289369
3646 3646 a, g dbSNP:117029005
3657 3657 c, t dbSNP:182177872
3664 3664 a, g dbSNP:145080926
3677 3677 g, t dbSNP:117013092
3745 3745 a, g dbSNP:745588097
3780 3780 a, g dbSNP:574435861
3799 3799 c, g dbSNP:751923452
3817 3817 c, t dbSNP:536452859
3832 3832 a, t dbSNP:556692842
3834 3834 a, g dbSNP:147617140
3855 3855 a, g dbSNP:545328879
3908 3908 a, g dbSNP:187260879
3918 3918 a, g dbSNP:11175698
3920 3920 c, t dbSNP:541374258
3962 3962 a, g dbSNP:561228677
4100 4100 a, g dbSNP:189997214
4106 4106 c, g dbSNP:752981509
4118 4118 g, t dbSNP:182146635
4129 4129 c, t dbSNP:756354816
4141 4141 c, t dbSNP:757929414
4148 4148 a, t dbSNP:779561172
4156 4156 c, t dbSNP:186082338
4157 4157 a, g dbSNP:558015357
4201 4201 c, g dbSNP:753923821
4243 4243 c, t dbSNP:113095916
4298 4298 a, c dbSNP:532321672
4319 4319 a, t dbSNP:549193776
4333 4333 c, t dbSNP:780029716
4397 4397 a, g dbSNP:12304180
4414 4414 g, t dbSNP:565972416
4450 4450 c, t dbSNP:534333586
4587 4587 a, g dbSNP:748869118
4626 4626 c, t dbSNP:548125457
4627 4627 a, g dbSNP:569318943
4630 4630 a, c dbSNP:531730005
4642 4642 c, t dbSNP:2888
4663 4663 a, g dbSNP:12071
4678 4678 a, g dbSNP:780910419
4687 4687 g, t dbSNP:144538196
4696 4696 c, t dbSNP:569944899
4713 4713 c, t dbSNP:11175699
4723 4723 g, t dbSNP:558833096
4755 4755 a, g dbSNP:201552989
4760 4760 -, tt dbSNP:761955596
4760 4760 -, t dbSNP:550813794
4768 4768 -, ta dbSNP:770015806
4769 4769 a, g dbSNP:139957956
4786 4786 a, g dbSNP:769400654

Target ORF information:

RefSeq Version NM_014319
Organism Homo sapiens (human)
Definition Homo sapiens LEM domain containing 3 (LEMD3), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_014319

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
ATGGCGGCGG CAGCAGCTTC GGCGCCTCAG CAGCTCTCGG ATGAGGAGCT TTTCTCTCAG 
CTCCGCCGTT ACGGCCTGTC TCCCGGACCA GTGACGGAGA GCACCCGCCC GGTCTACCTC
AAGAAGCTGA AGAAGCTTCG AGAGGAAGAG CAGCAACAGC ACCGGTCAGG GGGCCGCGGC
AACAAGACGC GGAACAGTAA TAACAATAAC ACGGCAGCCG CCACGGTCGC AGCCGCGGGA
CCAGCGGCGG CGGCGGCCGC GGGGATGGGG GTCCGGCCGG TCTCGGGCGA CCTCTCCTAC
TTACGGACTC CTGGGGGCCT GTGCCGAATC TCGGCCTCTG GCCCAGAGAG CCTCCTGGGA
GGGCCCGGGG GCGCCTCCGC CGCCCCCGCG GCTGGCAGCA AAGTGCTGCT GGGCTTCAGC
TCGGACGAGT CGGACGTGGA GGCCAGTCCC CGGGACCAGG CCGGCGGCGG CGGGAGGAAA
GACCGGGCTT CGCTCCAGTA CCGCGGGCTC AAAGCGCCGC CGGCGCCCCT GGCCGCCAGC
GAGGTGACTA ACAGCAACTC TGCAGAGCGA AGGAAGCCCC ACTCGTGGTG GGGGGCCAGG
AGGCCGGCGG GCCCCGAGCT GCAGACCCCG CCGGGGAAAG ATGGAGCAGT GGAGGACGAG
GAAGGGGAGG GAGAGGACGG TGAGGAGAGG GACCCGGAGA CCGAGGAGCC GCTCTGGGCG
AGCCGGACCG TGAATGGCAG CCGGCTTGTC CCCTACAGCT GCCGGGAAAA CTATTCGGAC
TCAGAGGAAG AGGACGACGA CGACGTGGCC TCCAGCAGAC AGGTATTAAA GGACGACTCC
CTTTCCCGGC ATCGGCCCAG ACGAACCCAT AGTAAGCCTC TCCCCCCGCT GACTGCTAAA
TCGGCCGGCG GCAGGCTGGA GACTTCAGTT CAGGGAGGGG GAGGACTCGC GATGAATGAC
AGGGCGGCGG CTGCCGGGAG TCTAGACAGG AGCCGAAACC TCGAAGAGGC GGCGGCCGCG
GAGCAGGGAG GAGGGTGTGA TCAAGTGGAC TCCAGCCCCG TTCCTAGATA CCGTGTTAAC
GCTAAGAAAC TGACCCCTCT CCTGCCCCCG CCACTTACTG ACATGGACTC AACCTTGGAT
TCGTCAACAG GCTCCCTTCT GAAAACCAAT AATCATATTG GCGGTGGGGC CTTCAGTGTG
GACTCCCCCA GGATTTATTC TAACAGTCTC CCTCCCAGTG CGGCGGTGGC CGCCTCTAGT
TCACTCAGGA TCAATCACGC CAATCATACG GGCTCCAATC ATACCTACCT GAAAAACACA
TACAACAAAC CGAAGCTTTC CGAACCCGAA GAGGAACTTC TCCAGCAATT TAAACGGGAG
GAGGTGTCCC CAACAGGGAG TTTCAGTGCC CACTACTTGT CGATGTTTCT CTTAACTGCT
GCCTGCTTAT TTTTCCTAAT ACTGGGACTG ACTTACCTAG GAATGAGAGG GACAGGAGTA
TCTGAGGATG GAGAACTCAG CATAGAAAAC CCCTTTGGTG AAACATTTGG AAAAATACAA
GAAAGTGAAA AAACTCTTAT GATGAACACA TTATATAAGC TTCATGATCG ATTGGCACAG
CTTGCAGGAG ATCATGAATG TGGCAGTTCT AGTCAAAGAA CGCTTTCTGT TCAAGAGGCA
GCTGCGTATT TAAAAGATTT AGGTCCTGAA TATGAAGGTA TATTTAACAC TTCATTGCAG
TGGATCTTAG AAAATGGAAA AGATGTTGGA ATAAGGTGTG TTGGTTTTGG CCCTGAGGAA
GAATTGACAA ATATAACTGA TGTGCAGTTT TTACAGTCCA CAAGACCACT GATGTCTTTT
TGGTGTCGTT TTCGACGTGC TTTTGTTACT GTAACTCACA GATTATTGTT GTTATGCTTA
GGTGTAGTGA TGGTTTGTGT CGTTCTGCGT TACATGAAAT ATCGATGGAC AAAAGAAGAG
GAGGAAACAA GGCAGATGTA TGATATGGTG GTAAAGATTA TAGATGTTTT ACGAAGTCAT
AATGAAGCCT GCCAGGAAAA CAAAGATTTA CAACCTTACA TGCCTATTCC ACATGTACGC
GATTCCTTAA TACAGCCTCA TGACAGGAAA AAAATGAAGA AAGTCTGGGA TAGAGCTGTT
GACTTCCTTG CTGCTAATGA GTCTAGAGTT CGCACGGAAA CACGAAGAAT AGGTGGTGCA
GATTTTCTGG TTTGGCGGTG GATCCAGCCT TCTGCATCCT GTGACAAAAT ATTAGTTATA
CCTTCTAAAG TATGGCAAGG TCAAGCATTT CATTTAGATA GAAGAAATTC ACCACCAAAT
AGTTTGACAC CGTGTCTAAA GATTCGGAAT ATGTTTGATC CCGTTATGGA AATAGGGGAT
CAGTGGCATT TGGCAATTCA AGAAGCAATT TTAGAAAAAT GCAGTGATAA TGATGGCATT
GTTCACATTG CAGTAGACAA AAATTCACGT GAGGGTTGTG TATATGTTAA ATGTCTGTCT
CCAGAATATG CTGGAAAGGC TTTTAAAGCA TTGCATGGCT CTTGGTTTGA TGGGAAATTG
GTTACAGTAA AATATTTACG ACTAGATAGA TACCACCATC GCTTTCCCCA GGCTCTCACT
TCCAACACTC CATTGAAGCC ATCAAATAAA CATATGAACT CCATGTCTCA TCTTCGTCTT
CGGACTGGCC TAACCAATTC TCAAGGAAGT TCCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu04065
Accession Version NM_001167614.1
Sequence Information ORF Nucleotide Sequence (Length: 2733bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product inner nuclear membrane protein Man1 isoform 2
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK312473.1, AF112299.2 and BX390128.2. Summary: This locus encodes a LEM domain-containing protein. The encoded protein functions to antagonize transforming growth factor-beta signaling at the inner nuclear membrane. Two transcript variants encoding different isoforms have been found for this gene. Mutations in this gene have been associated with osteopoikilosis, Buschke-Ollendorff syndrome and melorheostosis.[provided by RefSeq, Nov 2009]. Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 5' coding region, compared to variant 1. This results in a shorter protein (isoform 2), compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK312473.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2144335, SAMEA2145240 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
ATGGCGGCGG CAGCAGCTTC GGCGCCTCAG CAGCTCTCGG ATGAGGAGCT TTTCTCTCAG 
CTCCGCCGTT ACGGCCTGTC TCCCGGACCA GTGACGGAGA GCACCCGCCC GGTCTACCTC
AAGAAGCTGA AGAAGCTTCG AGAGGAAGAG CAGCAACAGC ACCGGTCAGG GGGCCGCGGC
AACAAGACGC GGAACAGTAA TAACAATAAC ACGGCAGCCG CCACGGTCGC AGCCGCGGGA
CCAGCGGCGG CGGCGGCCGC GGGGATGGGG GTCCGGCCGG TCTCGGGCGA CCTCTCCTAC
TTACGGACTC CTGGGGGCCT GTGCCGAATC TCGGCCTCTG GCCCAGAGAG CCTCCTGGGA
GGGCCCGGGG GCGCCTCCGC CGCCCCCGCG GCTGGCAGCA AAGTGCTGCT GGGCTTCAGC
TCGGACGAGT CGGACGTGGA GGCCAGTCCC CGGGACCAGG CCGGCGGCGG CGGGAGGAAA
GACCGGGCTT CGCTCCAGTA CCGCGGGCTC AAAGCGCCGC CGGCGCCCCT GGCCGCCAGC
GAGGTGACTA ACAGCAACTC TGCAGAGCGA AGGAAGCCCC ACTCGTGGTG GGGGGCCAGG
AGGCCGGCGG GCCCCGAGCT GCAGACCCCG CCGGGGAAAG ATGGAGCAGT GGAGGACGAG
GAAGGGGAGG GAGAGGACGG TGAGGAGAGG GACCCGGAGA CCGAGGAGCC GCTCTGGGCG
AGCCGGACCG TGAATGGCAG CCGGCTTGTC CCCTACAGCT GCCGGGAAAA CTATTCGGAC
TCAGAGGAAG AGGACGACGA CGACGTGGCC TCCAGCAGAC AGGTATTAAA GGACGACTCC
CTTTCCCGGC ATCGGCCCAG ACGAACCCAT AGTAAGCCTC TCCCCCCGCT GACTGCTAAA
TCGGCCGGCG GCAGGCTGGA GACTTCAGTT CAGGGAGGGG GAGGACTCGC GATGAATGAC
AGGGCGGCGG CTGCCGGGAG TCTAGACAGG AGCCGAAACC TCGAAGAGGC GGCGGCCGCG
GAGCAGGGAG GAGGGTGTGA TCAAGTGGAC TCCAGCCCCG TTCCTAGATA CCGTGTTAAC
GCTAAGAAAC TGACCCCTCT CCTGCCCCCG CCACTTACTG ACATGGACTC AACCTTGGAT
TCGTCAACAG GCTCCCTTCT GAAAACCAAT AATCATATTG GCGGTGGGGC CTTCAGTGTG
GACTCCCCCA GGATTTATTC TAACAGTCTC CCTCCCAGTG CGGCGGTGGC CGCCTCTAGT
TCACTCAGGA TCAATCACGC CAATCATACG GGCTCCAATC ATACCTACCT GAAAAACACA
TACAACAAAC CGAAGCTTTC CGAACCCGAA GAGGAACTTC TCCAGCAATT TAAACGGGAG
GAGGTGTCCC CAACAGGGAG TTTCAGTGCC CACTACTTGT CGATGTTTCT CTTAACTGCT
GCCTGCTTAT TTTTCCTAAT ACTGGGACTG ACTTACCTAG GAATGAGAGG GACAGGAGTA
TCTGAGGATG GAGAACTCAG CAAAAACCCC TTTGGTGAAA CATTTGGAAA AATACAAGAA
AGTGAAAAAA CTCTTATGAT GAACACATTA TATAAGCTTC ATGATCGATT GGCACAGCTT
GCAGGAGATC ATGAATGTGG CAGTTCTAGT CAAAGAACGC TTTCTGTTCA AGAGGCAGCT
GCGTATTTAA AAGATTTAGG TCCTGAATAT GAAGGTATAT TTAACACTTC ATTGCAGTGG
ATCTTAGAAA ATGGAAAAGA TGTTGGAATA AGGTGTGTTG GTTTTGGCCC TGAGGAAGAA
TTGACAAATA TAACTGATGT GCAGTTTTTA CAGTCCACAA GACCACTGAT GTCTTTTTGG
TGTCGTTTTC GACGTGCTTT TGTTACTGTA ACTCACAGAT TATTGTTGTT ATGCTTAGGT
GTAGTGATGG TTTGTGTCGT TCTGCGTTAC ATGAAATATC GATGGACAAA AGAAGAGGAG
GAAACAAGGC AGATGTATGA TATGGTGGTA AAGATTATAG ATGTTTTACG AAGTCATAAT
GAAGCCTGCC AGGAAAACAA AGATTTACAA CCTTACATGC CTATTCCACA TGTACGCGAT
TCCTTAATAC AGCCTCATGA CAGGAAAAAA ATGAAGAAAG TCTGGGATAG AGCTGTTGAC
TTCCTTGCTG CTAATGAGTC TAGAGTTCGC ACGGAAACAC GAAGAATAGG TGGTGCAGAT
TTTCTGGTTT GGCGGTGGAT CCAGCCTTCT GCATCCTGTG ACAAAATATT AGTTATACCT
TCTAAAGTAT GGCAAGGTCA AGCATTTCAT TTAGATAGAA GAAATTCACC ACCAAATAGT
TTGACACCGT GTCTAAAGAT TCGGAATATG TTTGATCCCG TTATGGAAAT AGGGGATCAG
TGGCATTTGG CAATTCAAGA AGCAATTTTA GAAAAATGCA GTGATAATGA TGGCATTGTT
CACATTGCAG TAGACAAAAA TTCACGTGAG GGTTGTGTAT ATGTTAAATG TCTGTCTCCA
GAATATGCTG GAAAGGCTTT TAAAGCATTG CATGGCTCTT GGTTTGATGG GAAATTGGTT
ACAGTAAAAT ATTTACGACT AGATAGATAC CACCATCGCT TTCCCCAGGC TCTCACTTCC
AACACTCCAT TGAAGCCATC AAATAAACAT ATGAACTCCA TGTCTCATCT TCGTCTTCGG
ACTGGCCTAA CCAATTCTCA AGGAAGTTCC TGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_001161086.1
CDS27..2759
Misc Feature(1)30..32(+)
Misc Feature(2)51..179(+)
Misc Feature(3)105..152(+)
Misc Feature(4)444..446(+)
Misc Feature(5)447..449(+)
Misc Feature(6)456..458(+)
Misc Feature(7)579..581(+)
Misc Feature(8)585..587(+)
Misc Feature(9)801..803(+)
Misc Feature(10)807..809(+)
Misc Feature(11)864..866(+)
Misc Feature(12)1080..1082(+)
Misc Feature(13)1119..1121(+)
Misc Feature(14)1230..1232(+)
Misc Feature(15)1449..1511(+)
Misc Feature(16)1578..2276(+)
Misc Feature(17)1905..1967(+)
Misc Feature(18)2118..2756(+)
Misc Feature(19)2352..2354(+)
Misc Feature(20)2376..2651(+)
Misc Feature(21)2670..2672(+)
Misc Feature(22)2754..2756(+)
Exon (1)1..1548
Gene:LEMD3
Gene Synonym:
Exon (2)1549..1583
Gene:LEMD3
Gene Synonym:
Exon (3)1584..1650
Gene:LEMD3
Gene Synonym:
Exon (4)1651..1718
Gene:LEMD3
Gene Synonym:
Exon (5)1719..1798
Gene:LEMD3
Gene Synonym:
Exon (6)1799..1944
Gene:LEMD3
Gene Synonym:
Exon (7)1945..2046
Gene:LEMD3
Gene Synonym:
Exon (8)2047..2149
Gene:LEMD3
Gene Synonym:
Exon (9)2150..2328
Gene:LEMD3
Gene Synonym:
Exon (10)2329..2410
Gene:LEMD3
Gene Synonym:
Exon (11)2411..2516
Gene:LEMD3
Gene Synonym:
Exon (12)2517..2595
Gene:LEMD3
Gene Synonym:
Exon (13)2596..4795
Gene:LEMD3
Gene Synonym:
Translation
Position Chain Variation Link
3 3 c, t dbSNP:779239307
4 4 c, t dbSNP:778401685
7 7 -, a dbSNP:752092179
12 12 c, g dbSNP:540958232
14 14 c, g, t dbSNP:758146972
15 15 c, t dbSNP:746522089
16 16 c, g, t dbSNP:560983978
17 17 c, t dbSNP:776776070
21 21 a, g dbSNP:747864180
28 28 -, ggc dbSNP:759986057
30 30 g, t dbSNP:769677064
34 34 c, t dbSNP:772903185
35 35 a, g dbSNP:763192267
39 39 a, g dbSNP:766588987
43 43 c, t dbSNP:774353434
44 44 c, t dbSNP:759674593
46 46 c, g, t dbSNP:768011921
48 48 a, g dbSNP:756414909
59 59 g, t dbSNP:764473245
60 60 c, t dbSNP:369764718
65 65 a, g dbSNP:373288363
66 66 a, g dbSNP:779865961
72 72 a, g dbSNP:746513740
80 80 c, g dbSNP:377077013
82 82 c, t dbSNP:780968500
84 84 c, g dbSNP:748067865
86 86 g, t dbSNP:769647254
87 87 c, t dbSNP:529619321
90 90 c, g dbSNP:749045900
91 91 c, g dbSNP:771132420
93 93 c, t dbSNP:774626762
98 98 c, t dbSNP:549481418
101 101 c, t dbSNP:767635681
104 104 a, g dbSNP:548059711
113 113 a, g dbSNP:775456269
119 119 a, g dbSNP:761206230
121 121 c, t dbSNP:201950187
125 125 a, g dbSNP:754174270
128 128 a, c dbSNP:762333553
136 136 c, g dbSNP:766098043
137 137 a, g dbSNP:569384904
144 144 c, t dbSNP:754698589
146 146 c, t dbSNP:780709633
152 152 a, g dbSNP:752150192
166 166 c, g dbSNP:756017417
185 185 a, g dbSNP:777625988
188 188 c, t dbSNP:150212307
189 189 c, g dbSNP:531792416
191 191 c, g dbSNP:138821698
201 201 c, t dbSNP:746044253
202 202 a, g dbSNP:772216122
204 204 a, g dbSNP:775574495
206 206 c, t dbSNP:760683855
211 211 a, c dbSNP:769194295
215 215 a, g dbSNP:777043878
218 218 a, g dbSNP:762245557
223 223 a, g dbSNP:765645790
225 225 a, c dbSNP:551911988
227 227 a, t dbSNP:750847187
228 228 -, aac dbSNP:767735305
231 231 a, g dbSNP:759189662
238 238 c, g dbSNP:767085294
239 239 a, g dbSNP:752234472
248 248 c, t dbSNP:755651275
250 250 a, c dbSNP:777739111
260 260 c, g dbSNP:753825048
265 265 c, g dbSNP:757211962
267 267 c, g dbSNP:778640480
268 268 c, g dbSNP:745669202
271 271 c, t dbSNP:772279938
289 289 a, g dbSNP:780199936
296 296 g, t dbSNP:747079226
318 318 c, t dbSNP:571742271
325 325 a, t dbSNP:768667554
347 347 a, g dbSNP:776870950
356 356 c, t dbSNP:534560505
362 362 c, t dbSNP:61736594
371 371 a, g dbSNP:530591432
377 377 c, t dbSNP:773651512
404 404 c, t dbSNP:61736593
409 409 c, t dbSNP:767190888
488 488 -, cgg dbSNP:750001959
541 541 a, c, t dbSNP:775048974
547 547 c, t dbSNP:536611944
559 559 c, t dbSNP:556713896
563 563 c, t dbSNP:753380295
570 570 g, t dbSNP:757121957
572 572 a, g dbSNP:576557496
574 574 -, t dbSNP:757886688
580 580 a, g dbSNP:750206660
581 581 c, t dbSNP:765520773
583 583 a, g dbSNP:758194466
594 594 c, g dbSNP:780300500
619 619 a, g dbSNP:201695195
634 634 a, c, t dbSNP:755257962
638 638 c, g dbSNP:748249096
644 644 a, g dbSNP:770408327
656 656 a, g dbSNP:773919248
659 659 c, g dbSNP:749637412
662 662 a, g dbSNP:771253349
666 666 g, t dbSNP:774803333
667 667 a, g dbSNP:760207766
675 675 c, g dbSNP:763742183
680 680 c, g dbSNP:558755661
687 687 c, g dbSNP:904411
692 692 a, g dbSNP:761371155
711 711 c, g dbSNP:765156027
719 719 c, t dbSNP:750409065
721 721 c, t dbSNP:758383183
722 722 a, g dbSNP:766047049
730 730 a, g dbSNP:751372115
735 735 c, t dbSNP:755095379
749 749 c, g dbSNP:781619701
755 755 c, g dbSNP:752878753
756 756 g, t dbSNP:748230618
763 763 a, g dbSNP:756299363
768 768 c, t dbSNP:778406683
770 770 g, t dbSNP:749713372
775 775 c, t dbSNP:771503173
776 776 c, g, t dbSNP:148964879
778 778 c, t dbSNP:768286122
779 779 a, c, t dbSNP:201160057
788 788 c, t dbSNP:769244916
789 789 c, t dbSNP:772810730
802 802 c, t dbSNP:762730876
804 804 g, t dbSNP:7487311
812 812 a, g dbSNP:766352719
815 815 a, g dbSNP:751296569
818 818 -, gac dbSNP:780012432
820 820 a, t dbSNP:759468776
825 825 c, g dbSNP:550697467
830 830 c, g dbSNP:541345339
835 835 c, t dbSNP:147082719
836 836 c, t dbSNP:756430180
839 839 c, t dbSNP:777964422
847 847 a, g dbSNP:561008904
860 860 c, t dbSNP:200222837
861 861 c, g dbSNP:376432823
865 865 c, t dbSNP:746216854
867 867 c, g dbSNP:747025576
873 873 -, cggcat dbSNP:746915404
873 873 a, c dbSNP:780417676
874 874 a, g dbSNP:747757104
883 883 c, g dbSNP:769441217
884 884 c, t dbSNP:138509307
887 887 a, c, g dbSNP:772538120
888 888 c, g dbSNP:144086377
891 891 a, g dbSNP:774384614
892 892 c, t dbSNP:769786244
896 896 c, t dbSNP:147328826
897 897 a, g dbSNP:551179499
903 903 c, g dbSNP:752572923
906 906 c, g dbSNP:760918161
908 908 -, c dbSNP:768525907
908 908 c, t dbSNP:764393737
909 909 c, t dbSNP:753850539
912 912 a, c, g dbSNP:757425587
913 913 c, g dbSNP:750988811
914 914 a, g, t dbSNP:758934476
919 919 c, t dbSNP:199824717
920 920 c, t dbSNP:755750425
930 930 g, t dbSNP:374194981
932 932 c, t dbSNP:376059733
933 933 g, t dbSNP:35221558
936 936 g, t dbSNP:551985147
939 939 a, g dbSNP:200784504
941 941 c, g dbSNP:745762772
954 954 g, t dbSNP:772145338
956 956 g, t dbSNP:775371062
961 961 a, g dbSNP:760605681
963 963 c, g, t dbSNP:200070970
964 964 c, g, t dbSNP:201615997
967 967 g, t dbSNP:750504733
969 969 c, g dbSNP:201228238
974 974 c, t dbSNP:183253527
976 976 c, g dbSNP:567928632
979 979 c, t dbSNP:199902847
986 986 c, g dbSNP:372553791
990 990 a, g dbSNP:755407121
991 991 c, t dbSNP:777266847
994 994 c, t dbSNP:748918240
995 995 a, g dbSNP:756894525
1001 1001 a, c, g, t dbSNP:375580551
1003 1003 a, g dbSNP:775636778
1009 1009 c, t dbSNP:746769484
1014 1014 a, t dbSNP:768546772
1026 1026 a, c, g dbSNP:147262660
1028 1028 c, g dbSNP:765389652
1033 1033 -, ggc dbSNP:780794872
1034 1034 a, g dbSNP:773266350
1039 1039 c, g, t dbSNP:150526974
1043 1043 c, g dbSNP:752106074
1044 1044 a, g dbSNP:755459590
1048 1048 a, t dbSNP:767880318
1049 1049 a, g dbSNP:753010858
1062 1062 g, t dbSNP:756879696
1085 1085 a, c, g dbSNP:770601096
1086 1086 a, c, g dbSNP:758022128
1089 1089 c, t dbSNP:202161021
1101 1101 a, g dbSNP:376822761
1104 1104 a, c dbSNP:780981110
1120 1120 c, t dbSNP:747950441
1123 1123 c, g, t dbSNP:199884145
1124 1124 c, t dbSNP:762994114
1125 1125 c, t dbSNP:139507581
1129 1129 c, t dbSNP:202245561
1131 1131 c, t dbSNP:371098833
1133 1133 c, g dbSNP:767925680
1134 1134 a, c dbSNP:200288324
1135 1135 c, t dbSNP:201542546
1146 1146 c, g dbSNP:764953197
1151 1151 a, g dbSNP:750150042
1152 1152 g, t dbSNP:758148747
1161 1161 c, t dbSNP:368502571
1171 1171 c, t dbSNP:751043353
1173 1173 a, g dbSNP:143295477
1180 1180 c, t dbSNP:372588607
1182 1182 c, t dbSNP:554852726
1185 1185 c, g, t dbSNP:146241425
1194 1194 a, g dbSNP:749468914
1195 1195 a, g dbSNP:771144409
1200 1200 c, t dbSNP:774359633
1202 1202 c, t dbSNP:759594603
1204 1204 c, t dbSNP:367612390
1211 1211 c, g, t dbSNP:775902004
1220 1220 a, c dbSNP:372402033
1221 1221 a, g dbSNP:754287790
1228 1228 a, t dbSNP:759247239
1231 1231 c, t dbSNP:139346096
1243 1243 -, attcta dbSNP:748410937
1257 1257 c, t dbSNP:766191006
1261 1261 c, g dbSNP:751075559
1269 1269 c, g dbSNP:754487253
1276 1276 c, t dbSNP:199605857
1284 1284 a, g dbSNP:752524303
1295 1295 g, t dbSNP:756074055
1296 1296 a, g dbSNP:201129667
1297 1297 a, t dbSNP:777476143
1300 1300 a, g dbSNP:562992922
1309 1309 a, g dbSNP:749097407
1311 1311 c, t dbSNP:757460816
1321 1321 c, t dbSNP:779074454
1324 1324 a, g dbSNP:745933801
1330 1330 a, c dbSNP:768302841
1338 1338 a, g dbSNP:775662292
1345 1345 a, c dbSNP:747480471
1356 1356 c, g dbSNP:144127577
1357 1357 c, t dbSNP:569480939
1366 1366 c, g dbSNP:762333334
1367 1367 c, t dbSNP:766097829
1371 1371 c, t dbSNP:371748000
1376 1376 a, g dbSNP:145116568
1381 1381 -, a dbSNP:756668294
1381 1381 a, g dbSNP:766893227
1419 1419 a, g dbSNP:376067130
1422 1422 a, g dbSNP:755984431
1423 1423 a, g dbSNP:764079361
1425 1425 a, g, t dbSNP:199915804
1453 1453 g, t dbSNP:371901972
1457 1457 c, t dbSNP:547625447
1462 1462 c, g, t dbSNP:200415494
1463 1463 g, t dbSNP:149129862
1464 1464 a, g dbSNP:758680061
1469 1469 a, c dbSNP:779934044
1475 1475 a, g dbSNP:747141497
1487 1487 a, g dbSNP:769281226
1491 1491 a, g, t dbSNP:777316626
1495 1495 g, t dbSNP:770000098
1514 1514 a, g dbSNP:773654384
1516 1516 a, g dbSNP:759040154
1524 1524 g, t dbSNP:142265837
1529 1529 a, t dbSNP:774970317
1534 1534 a, g dbSNP:760247162
1540 1540 a, g dbSNP:375079599
1553 1553 a, c, t dbSNP:749717670
1557 1557 g, t dbSNP:369113542
1569 1569 -, ttggaa dbSNP:759909210
1570 1570 g, t dbSNP:760159217
1587 1587 a, c dbSNP:779276438
1594 1594 a, c dbSNP:746625092
1609 1609 a, g dbSNP:151256200
1618 1618 a, g dbSNP:776062606
1633 1633 a, g dbSNP:761447049
1643 1643 a, g dbSNP:769585910
1654 1654 a, c, g dbSNP:774273011
1655 1655 a, t dbSNP:767819719
1667 1667 c, g dbSNP:553028286
1672 1672 c, g dbSNP:760830144
1675 1675 a, g dbSNP:764193615
1682 1682 a, g dbSNP:753873005
1684 1684 c, t dbSNP:188376092
1686 1686 a, c dbSNP:765794322
1690 1690 c, t dbSNP:750784348
1700 1700 g, t dbSNP:758808182
1705 1705 c, t dbSNP:780415646
1708 1708 c, t dbSNP:747793228
1709 1709 a, g dbSNP:755722811
1711 1711 a, g dbSNP:375964932
1728 1728 c, t dbSNP:374655981
1743 1743 a, g dbSNP:374107839
1745 1745 a, g dbSNP:368041039
1751 1751 a, c dbSNP:565217537
1752 1752 a, t dbSNP:745760794
1755 1755 g, t dbSNP:566358684
1758 1758 c, t dbSNP:779844005
1767 1767 a, g dbSNP:371485270
1769 1769 c, t dbSNP:140496862
1770 1770 a, t dbSNP:776761325
1774 1774 a, g dbSNP:762043417
1781 1781 a, g dbSNP:769822113
1785 1785 c, g dbSNP:773280693
1786 1786 a, g dbSNP:112859075
1790 1790 g, t dbSNP:763389434
1799 1799 a, g dbSNP:749967974
1806 1806 a, g dbSNP:758347889
1815 1815 c, t dbSNP:779926136
1827 1827 c, t dbSNP:746792069
1829 1829 c, g dbSNP:768283662
1833 1833 a, g dbSNP:185283829
1837 1837 c, t dbSNP:748299191
1841 1841 c, t dbSNP:770011862
1847 1847 a, g, t dbSNP:372338782
1849 1849 a, g dbSNP:771435908
1850 1850 a, g dbSNP:774767140
1857 1857 a, c dbSNP:760112650
1861 1861 a, c dbSNP:368604047
1871 1871 a, g dbSNP:767735135
1874 1874 c, g dbSNP:776002588
1883 1883 c, t dbSNP:761499461
1890 1890 c, t dbSNP:200189969
1891 1891 a, g dbSNP:765045080
1896 1896 a, c, t dbSNP:749951964
1897 1897 a, g dbSNP:766320286
1900 1900 a, g dbSNP:751409394
1902 1902 a, g dbSNP:376680164
1904 1904 c, t dbSNP:780904042
1915 1915 c, t dbSNP:747990796
1922 1922 c, t dbSNP:200578207
1925 1925 a, g dbSNP:778009960
1938 1938 a, t dbSNP:749363247
1954 1954 c, t dbSNP:754855189
1956 1956 a, g dbSNP:369133002
1964 1964 c, g dbSNP:373040508
1972 1972 a, g dbSNP:202030550
1974 1974 g, t dbSNP:777566184
1979 1979 a, g dbSNP:749433061
1986 1986 c, t dbSNP:267607217
1987 1987 a, g dbSNP:757507566
2003 2003 a, g dbSNP:576862487
2004 2004 a, g dbSNP:374790398
2018 2018 a, g dbSNP:746019192
2029 2029 c, t dbSNP:772706117
2036 2036 a, c dbSNP:780751263
2037 2037 a, g dbSNP:538856716
2038 2038 a, c dbSNP:769095661
2039 2039 g, t dbSNP:777055317
2040 2040 a, t dbSNP:762453236
2042 2042 c, t dbSNP:770671188
2049 2049 a, g dbSNP:769297537
2050 2050 c, t dbSNP:201433608
2054 2054 a, g dbSNP:748609383
2056 2056 a, c, g dbSNP:770458284
2062 2062 a, g dbSNP:200391612
2063 2063 c, t dbSNP:541359325
2065 2065 a, g dbSNP:774986795
2066 2066 c, t dbSNP:760549628
2071 2071 a, c dbSNP:764077258
2079 2079 a, g dbSNP:147072982
2085 2085 a, g dbSNP:761711143
2086 2086 a, g dbSNP:199542833
2092 2092 c, t dbSNP:750611668
2106 2106 c, g dbSNP:758728629
2109 2109 a, g dbSNP:762830732
2114 2114 a, g, t dbSNP:751745237
2115 2115 c, g dbSNP:369198842
2118 2118 c, g dbSNP:781741006
2121 2121 c, t dbSNP:373577886
2122 2122 a, g, t dbSNP:367618543
2123 2123 c, t dbSNP:199712960
2125 2125 a, g dbSNP:370494111
2128 2128 a, c dbSNP:543788718
2130 2130 c, t dbSNP:373975270
2168 2168 a, c, g dbSNP:534883939
2174 2174 c, t dbSNP:758041929
2180 2180 c, t dbSNP:368699453
2191 2191 a, t dbSNP:746504394
2199 2199 a, c dbSNP:768168248
2200 2200 a, g dbSNP:776038819
2206 2206 c, g dbSNP:748053712
2214 2214 c, t dbSNP:769674069
2215 2215 g, t dbSNP:773133991
2218 2218 c, t dbSNP:376437712
2219 2219 a, g dbSNP:138445113
2238 2238 a, g dbSNP:180693560
2251 2251 c, t dbSNP:759706763
2254 2254 c, t dbSNP:767566947
2259 2259 c, t dbSNP:752732536
2265 2265 a, g dbSNP:76293710
2267 2267 c, t dbSNP:764652307
2273 2273 g, t dbSNP:754173455
2281 2281 c, g dbSNP:577090853
2282 2282 c, t dbSNP:757668158
2286 2286 a, g dbSNP:142542896
2287 2287 a, g dbSNP:779192767
2299 2299 -, atctgagg dbSNP:746387692
2301 2301 a, t dbSNP:754595680
2302 2302 c, t dbSNP:546005703
2304 2304 c, t dbSNP:747674456
2318 2318 g, t dbSNP:769735325
2321 2321 a, c, g dbSNP:777903247
2341 2341 a, g dbSNP:750770845
2354 2354 a, c dbSNP:146896083
2358 2358 c, t dbSNP:780743767
2361 2361 a, c dbSNP:752226487
2371 2371 c, t dbSNP:755527292
2375 2375 a, g dbSNP:777455273
2389 2389 a, g dbSNP:749169259
2406 2406 a, g dbSNP:549092592
2409 2409 a, t dbSNP:200170180
2410 2410 c, t dbSNP:745716875
2415 2415 a, t dbSNP:757257470
2416 2416 c, t dbSNP:778755584
2420 2420 g, t dbSNP:138951987
2421 2421 g, t dbSNP:745655839
2434 2434 c, t dbSNP:758081622
2448 2448 a, g dbSNP:779933634
2451 2451 a, g dbSNP:747136567
2458 2458 a, g dbSNP:768883372
2467 2467 a, g dbSNP:776683114
2471 2471 g, t dbSNP:748264298
2472 2472 a, g dbSNP:770259439
2483 2483 g, t dbSNP:199856827
2489 2489 c, t dbSNP:773539826
2494 2494 c, t dbSNP:763543576
2511 2511 c, t dbSNP:766583566
2512 2512 g, t dbSNP:774790837
2517 2517 a, c, g dbSNP:758364295
2519 2519 c, t dbSNP:201325184
2552 2552 c, t dbSNP:755193050
2554 2554 c, g dbSNP:756266770
2557 2557 a, g dbSNP:200089211
2558 2558 a, t dbSNP:748387291
2561 2561 c, g dbSNP:769822240
2577 2577 c, t dbSNP:367781819
2582 2582 c, t dbSNP:371626791
2587 2587 a, g dbSNP:267607216
2593 2593 a, t dbSNP:749698901
2595 2595 -, g dbSNP:767408063
2609 2609 a, g dbSNP:754715782
2619 2619 a, t dbSNP:780993841
2622 2622 c, t dbSNP:376937981
2640 2640 c, t dbSNP:752848029
2641 2641 a, g dbSNP:149439907
2645 2645 c, g dbSNP:143860838
2660 2660 c, t dbSNP:369210837
2668 2668 a, g dbSNP:201986205
2676 2676 c, t dbSNP:371624142
2681 2681 a, g dbSNP:17101179
2684 2684 a, g dbSNP:141624082
2688 2688 a, g dbSNP:146215492
2696 2696 c, t dbSNP:548156782
2703 2703 -, c dbSNP:749531910
2707 2707 c, t dbSNP:772526332
2710 2710 c, t dbSNP:745816602
2712 2712 c, t dbSNP:772006079
2717 2717 -, tcg dbSNP:757484190
2718 2718 c, t dbSNP:201280850
2719 2719 a, g dbSNP:761501582
2724 2724 c, t dbSNP:201930700
2725 2725 a, g dbSNP:376532238
2731 2731 g, t dbSNP:762568799
2732 2732 a, c dbSNP:765824548
2738 2738 c, t dbSNP:139254649
2740 2740 a, g dbSNP:759470441
2747 2747 a, g dbSNP:767239085
2751 2751 a, g dbSNP:752543800
2756 2756 c, t dbSNP:756284214
2763 2763 g, t dbSNP:779756206
2764 2764 a, g dbSNP:753840503
2772 2772 c, t dbSNP:369548419
2773 2773 c, t dbSNP:373665363
2782 2782 a, g dbSNP:779167118
2796 2796 a, g, t dbSNP:374013073
2801 2801 -, aa dbSNP:779188112
2810 2810 a, g dbSNP:376436071
2852 2852 a, g dbSNP:533399241
2888 2888 a, g dbSNP:536443053
2905 2905 a, g dbSNP:746798464
2929 2929 a, g dbSNP:146145624
2957 2957 c, t dbSNP:569925368
2984 2984 a, g dbSNP:139476203
2991 2991 c, t dbSNP:558557521
3006 3006 a, g dbSNP:202237128
3009 3009 a, g dbSNP:572184079
3054 3054 g, t dbSNP:200928805
3074 3074 -, a dbSNP:747017729
3099 3099 g, t dbSNP:188694142
3121 3121 c, t dbSNP:181182810
3159 3159 c, t dbSNP:574201881
3206 3206 c, t dbSNP:768359330
3235 3235 c, t dbSNP:144515474
3246 3246 c, t dbSNP:563052297
3271 3271 a, g dbSNP:375342655
3282 3282 a, g dbSNP:576284776
3291 3291 a, g dbSNP:545023029
3312 3312 a, g dbSNP:183716212
3335 3335 a, g dbSNP:527664684
3351 3351 c, g dbSNP:547604504
3368 3368 c, g dbSNP:769310674
3408 3408 a, g dbSNP:561424277
3414 3414 c, t dbSNP:12302249
3447 3447 c, t dbSNP:188087693
3484 3484 a, g dbSNP:569987408
3504 3504 a, t dbSNP:148427854
3524 3524 g, t dbSNP:199619679
3552 3552 -, agtatt dbSNP:768289369
3643 3643 a, g dbSNP:117029005
3654 3654 c, t dbSNP:182177872
3661 3661 a, g dbSNP:145080926
3674 3674 g, t dbSNP:117013092
3742 3742 a, g dbSNP:745588097
3777 3777 a, g dbSNP:574435861
3796 3796 c, g dbSNP:751923452
3814 3814 c, t dbSNP:536452859
3829 3829 a, t dbSNP:556692842
3831 3831 a, g dbSNP:147617140
3852 3852 a, g dbSNP:545328879
3905 3905 a, g dbSNP:187260879
3915 3915 a, g dbSNP:11175698
3917 3917 c, t dbSNP:541374258
3959 3959 a, g dbSNP:561228677
4097 4097 a, g dbSNP:189997214
4103 4103 c, g dbSNP:752981509
4115 4115 g, t dbSNP:182146635
4126 4126 c, t dbSNP:756354816
4138 4138 c, t dbSNP:757929414
4145 4145 a, t dbSNP:779561172
4153 4153 c, t dbSNP:186082338
4154 4154 a, g dbSNP:558015357
4198 4198 c, g dbSNP:753923821
4240 4240 c, t dbSNP:113095916
4295 4295 a, c dbSNP:532321672
4316 4316 a, t dbSNP:549193776
4330 4330 c, t dbSNP:780029716
4394 4394 a, g dbSNP:12304180
4411 4411 g, t dbSNP:565972416
4447 4447 c, t dbSNP:534333586
4584 4584 a, g dbSNP:748869118
4623 4623 c, t dbSNP:548125457
4624 4624 a, g dbSNP:569318943
4627 4627 a, c dbSNP:531730005
4639 4639 c, t dbSNP:2888
4660 4660 a, g dbSNP:12071
4675 4675 a, g dbSNP:780910419
4684 4684 g, t dbSNP:144538196
4693 4693 c, t dbSNP:569944899
4710 4710 c, t dbSNP:11175699
4720 4720 g, t dbSNP:558833096
4752 4752 a, g dbSNP:201552989
4757 4757 -, tt dbSNP:761955596
4757 4757 -, t dbSNP:550813794
4765 4765 -, ta dbSNP:770015806
4766 4766 a, g dbSNP:139957956
4783 4783 a, g dbSNP:769400654

Target ORF information:

RefSeq Version NM_001167614
Organism Homo sapiens (human)
Definition Homo sapiens LEM domain containing 3 (LEMD3), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001167614

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
ATGGCGGCGG CAGCAGCTTC GGCGCCTCAG CAGCTCTCGG ATGAGGAGCT TTTCTCTCAG 
CTCCGCCGTT ACGGCCTGTC TCCCGGACCA GTGACGGAGA GCACCCGCCC GGTCTACCTC
AAGAAGCTGA AGAAGCTTCG AGAGGAAGAG CAGCAACAGC ACCGGTCAGG GGGCCGCGGC
AACAAGACGC GGAACAGTAA TAACAATAAC ACGGCAGCCG CCACGGTCGC AGCCGCGGGA
CCAGCGGCGG CGGCGGCCGC GGGGATGGGG GTCCGGCCGG TCTCGGGCGA CCTCTCCTAC
TTACGGACTC CTGGGGGCCT GTGCCGAATC TCGGCCTCTG GCCCAGAGAG CCTCCTGGGA
GGGCCCGGGG GCGCCTCCGC CGCCCCCGCG GCTGGCAGCA AAGTGCTGCT GGGCTTCAGC
TCGGACGAGT CGGACGTGGA GGCCAGTCCC CGGGACCAGG CCGGCGGCGG CGGGAGGAAA
GACCGGGCTT CGCTCCAGTA CCGCGGGCTC AAAGCGCCGC CGGCGCCCCT GGCCGCCAGC
GAGGTGACTA ACAGCAACTC TGCAGAGCGA AGGAAGCCCC ACTCGTGGTG GGGGGCCAGG
AGGCCGGCGG GCCCCGAGCT GCAGACCCCG CCGGGGAAAG ATGGAGCAGT GGAGGACGAG
GAAGGGGAGG GAGAGGACGG TGAGGAGAGG GACCCGGAGA CCGAGGAGCC GCTCTGGGCG
AGCCGGACCG TGAATGGCAG CCGGCTTGTC CCCTACAGCT GCCGGGAAAA CTATTCGGAC
TCAGAGGAAG AGGACGACGA CGACGTGGCC TCCAGCAGAC AGGTATTAAA GGACGACTCC
CTTTCCCGGC ATCGGCCCAG ACGAACCCAT AGTAAGCCTC TCCCCCCGCT GACTGCTAAA
TCGGCCGGCG GCAGGCTGGA GACTTCAGTT CAGGGAGGGG GAGGACTCGC GATGAATGAC
AGGGCGGCGG CTGCCGGGAG TCTAGACAGG AGCCGAAACC TCGAAGAGGC GGCGGCCGCG
GAGCAGGGAG GAGGGTGTGA TCAAGTGGAC TCCAGCCCCG TTCCTAGATA CCGTGTTAAC
GCTAAGAAAC TGACCCCTCT CCTGCCCCCG CCACTTACTG ACATGGACTC AACCTTGGAT
TCGTCAACAG GCTCCCTTCT GAAAACCAAT AATCATATTG GCGGTGGGGC CTTCAGTGTG
GACTCCCCCA GGATTTATTC TAACAGTCTC CCTCCCAGTG CGGCGGTGGC CGCCTCTAGT
TCACTCAGGA TCAATCACGC CAATCATACG GGCTCCAATC ATACCTACCT GAAAAACACA
TACAACAAAC CGAAGCTTTC CGAACCCGAA GAGGAACTTC TCCAGCAATT TAAACGGGAG
GAGGTGTCCC CAACAGGGAG TTTCAGTGCC CACTACTTGT CGATGTTTCT CTTAACTGCT
GCCTGCTTAT TTTTCCTAAT ACTGGGACTG ACTTACCTAG GAATGAGAGG GACAGGAGTA
TCTGAGGATG GAGAACTCAG CAAAAACCCC TTTGGTGAAA CATTTGGAAA AATACAAGAA
AGTGAAAAAA CTCTTATGAT GAACACATTA TATAAGCTTC ATGATCGATT GGCACAGCTT
GCAGGAGATC ATGAATGTGG CAGTTCTAGT CAAAGAACGC TTTCTGTTCA AGAGGCAGCT
GCGTATTTAA AAGATTTAGG TCCTGAATAT GAAGGTATAT TTAACACTTC ATTGCAGTGG
ATCTTAGAAA ATGGAAAAGA TGTTGGAATA AGGTGTGTTG GTTTTGGCCC TGAGGAAGAA
TTGACAAATA TAACTGATGT GCAGTTTTTA CAGTCCACAA GACCACTGAT GTCTTTTTGG
TGTCGTTTTC GACGTGCTTT TGTTACTGTA ACTCACAGAT TATTGTTGTT ATGCTTAGGT
GTAGTGATGG TTTGTGTCGT TCTGCGTTAC ATGAAATATC GATGGACAAA AGAAGAGGAG
GAAACAAGGC AGATGTATGA TATGGTGGTA AAGATTATAG ATGTTTTACG AAGTCATAAT
GAAGCCTGCC AGGAAAACAA AGATTTACAA CCTTACATGC CTATTCCACA TGTACGCGAT
TCCTTAATAC AGCCTCATGA CAGGAAAAAA ATGAAGAAAG TCTGGGATAG AGCTGTTGAC
TTCCTTGCTG CTAATGAGTC TAGAGTTCGC ACGGAAACAC GAAGAATAGG TGGTGCAGAT
TTTCTGGTTT GGCGGTGGAT CCAGCCTTCT GCATCCTGTG ACAAAATATT AGTTATACCT
TCTAAAGTAT GGCAAGGTCA AGCATTTCAT TTAGATAGAA GAAATTCACC ACCAAATAGT
TTGACACCGT GTCTAAAGAT TCGGAATATG TTTGATCCCG TTATGGAAAT AGGGGATCAG
TGGCATTTGG CAATTCAAGA AGCAATTTTA GAAAAATGCA GTGATAATGA TGGCATTGTT
CACATTGCAG TAGACAAAAA TTCACGTGAG GGTTGTGTAT ATGTTAAATG TCTGTCTCCA
GAATATGCTG GAAAGGCTTT TAAAGCATTG CATGGCTCTT GGTTTGATGG GAAATTGGTT
ACAGTAAAAT ATTTACGACT AGATAGATAC CACCATCGCT TTCCCCAGGC TCTCACTTCC
AACACTCCAT TGAAGCCATC AAATAAACAT ATGAACTCCA TGTCTCATCT TCGTCTTCGG
ACTGGCCTAA CCAATTCTCA AGGAAGTTCC TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.