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MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F [Homo sapiens (human)]

Gene Symbol MAFF
Entrez Gene ID 23764
Full Name v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
Synonyms U-MAF, hMafF
General protein information
Preferred Names
transcription factor MafF
Names
transcription factor MafF
v-maf avian musculoaponeurotic fibrosarcoma oncogene family protein F
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

22

22q13.1

Summary The protein encoded by this gene is a basic leucine zipper (bZIP) transcription factor that lacks a transactivation domain. It is known to bind the US-2 DNA element in the promoter of the oxytocin receptor (OTR) gene and most likely heterodimerizes with other leucine zipper-containing proteins to enhance expression of the OTR gene during term pregnancy. The encoded protein can also form homodimers, and since it lacks a transactivation domain, the homodimer may act as a repressor of transcription. This gene may also be involved in the cellular stress response. Multiple transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2009]. lac of sum
Disorder MIM:

604877

Disorder Html:
CloneID RefSeq Accession Definition **Vector *Turnaround time Price
OHu31535 NM_012323 Homo sapiens v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F (MAFF), transcript variant 1, mRNA. pcDNA3.1-C-(k)DYK In stock -1 Starting from $99.00
OHu31535 NM_001161572 Homo sapiens v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F (MAFF), transcript variant 3, mRNA. pcDNA3.1-C-(k)DYK In stock -1 Starting from $99.00
OHu31535 NM_001161573 Homo sapiens v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F (MAFF), transcript variant 4, mRNA. pcDNA3.1-C-(k)DYK In stock -1 Starting from $99.00
OHu03210 NM_001161574 Homo sapiens v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F (MAFF), transcript variant 5, mRNA. pcDNA3.1-C-(k)DYK In stock -1 Starting from $99.00

*Business Day
**You may select a custom vector to replace pcDNA3.1-C-(k)DYK after clone is added to cart.



CloneID OHu31535D
Sequence Information ORF Nucleotide Sequence (Length: 495bp)
Protein sequence
SNP
Vector pcDNA3.1-C-(k)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1-C-(k)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product transcription factor MafF isoform a
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA209378.1, DA654696.1, AK002001.1, DB319587.1, AJ010857.1 and AI610651.1. On Jun 6, 2009 this sequence version replaced gi:23111001. Summary: The protein encoded by this gene is a basic leucine zipper (bZIP) transcription factor that lacks a transactivation domain. It is known to bind the US-2 DNA element in the promoter of the oxytocin receptor (OTR) gene and most likely heterodimerizes with other leucine zipper-containing proteins to enhance expression of the OTR gene during term pregnancy. The encoded protein can also form homodimers, and since it lacks a transactivation domain, the homodimer may act as a repressor of transcription. This gene may also be involved in the cellular stress response. Multiple transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2009]. Transcript Variant: This variant (1) differs in the 5' UTR compared to variant 3. Variants 1, 3, and 4 encode the same isoform (a). ##Evidence-Data-START## Transcript exon combination :: DA209378.1, BC067751.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
ATGTCTGTGG ATCCCCTATC CAGCAAAGCT CTAAAGATCA AGCGAGAGCT GAGCGAGAAC 
ACGCCGCACC TGTCGGACGA GGCGCTGATG GGGCTGTCGG TGCGCGAGCT GAACCGGCAT
CTGCGCGGGC TCTCCGCCGA GGAGGTGACA CGGCTCAAGC AGCGGCGCCG CACACTCAAA
AACCGTGGCT ACGCCGCCAG CTGCCGCGTG AAGCGCGTGT GCCAGAAGGA GGAGCTGCAG
AAGCAGAAGT CGGAGCTGGA GCGCGAGGTG GACAAGCTGG CGCGCGAGAA CGCCGCCATG
CGCCTGGAGC TCGACGCGCT GCGCGGCAAG TGCGAGGCGC TGCAGGGCTT CGCGCGCTCC
GTGGCCGCCG CCCGCGGGCC CGCCACGCTC GTGGCGCCGG CCAGCGTCAT CACCATCGTC
AAGTCCACCC CGGGCTCGGG GTCTGGCCCC GCCCACGGCC CGGACCCCGC CCACGGCCCG
GCCTCCTGCT CCTAG
The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.
RefSeqNP_036455.1
CDS313..807
Misc Feature(1)58..60(+)
Misc Feature(2)451..657(+)
Misc Feature(3)451..657(+)
Misc Feature(4)463..540(+)
Misc Feature(5)478..528(+)
Misc Feature(6)526..636(+)
Misc Feature(7)547..591(+)
Exon (1)1..281
Gene:MAFF
Gene Synonym:
Exon (2)282..348
Gene:MAFF
Gene Synonym:
Exon (3)349..2440
Gene:MAFF
Gene Synonym:
Translation
Position Chain Variation Link
19 19 a, g dbSNP:550901328
29 29 a, g dbSNP:569048551
87 87 c, g dbSNP:529977800
103 103 c, t dbSNP:11703601
138 138 a, g dbSNP:566644674
156 156 c, g dbSNP:909629
166 166 a, c dbSNP:558760164
242 242 a, g dbSNP:140153593
282 282 g, t dbSNP:369326133
283 283 c, t dbSNP:779231199
284 284 c, t dbSNP:746196239
287 287 c, t dbSNP:772508467
295 295 a, t dbSNP:775818328
296 296 g, t dbSNP:761247161
312 312 c, g, t dbSNP:373498296
314 314 c, t dbSNP:762592473
321 321 a, g dbSNP:766108175
328 328 c, g dbSNP:145033364
330 330 a, c dbSNP:759216253
331 331 c, t dbSNP:377667070
342 342 g, t dbSNP:752522153
344 344 c, t dbSNP:140474993
351 351 c, g dbSNP:374499428
353 353 a, c dbSNP:758643505
366 366 a, c dbSNP:780182396
369 369 a, g dbSNP:747356045
374 374 c, t dbSNP:755417006
381 381 c, t dbSNP:539101232
387 387 g, t dbSNP:748674205
390 390 a, c dbSNP:770292607
391 391 a, g dbSNP:773901929
396 396 a, g dbSNP:745433034
399 399 a, g dbSNP:771721927
415 415 a, c dbSNP:775168420
435 435 a, g dbSNP:760410351
436 436 a, c dbSNP:763907616
440 440 g, t dbSNP:776484507
456 456 a, g dbSNP:761751184
459 459 a, g dbSNP:765144379
463 463 c, t dbSNP:750486792
490 490 -, a dbSNP:755031237
491 491 a, g dbSNP:762993702
494 494 a, t dbSNP:766575506
501 501 c, g dbSNP:751863340
507 507 c, t dbSNP:755331154
535 535 c, t dbSNP:781703810
540 540 a, g dbSNP:753173557
552 552 a, g dbSNP:756643749
563 563 c, t dbSNP:367755646
583 583 a, g dbSNP:745357714
591 591 c, g dbSNP:771500797
622 622 c, t dbSNP:779641780
627 627 c, t dbSNP:746668329
667 667 c, t dbSNP:768380103
675 675 a, g dbSNP:776395712
726 726 c, t dbSNP:575686077
730 730 a, g dbSNP:372940204
734 734 a, g dbSNP:537001159
743 743 a, c dbSNP:769751288
745 745 g, t dbSNP:773046312
775 775 a, g dbSNP:375946855
778 778 c, t dbSNP:370305629
817 817 c, t dbSNP:766574334
828 828 c, t dbSNP:554955876
869 869 c, t dbSNP:759821374
927 927 a, g dbSNP:559332974
928 928 c, t dbSNP:767920699
935 935 c, t dbSNP:753077533
939 939 c, t dbSNP:756482362
942 942 a, g dbSNP:188743876
949 949 a, g dbSNP:540474027
955 955 c, g dbSNP:73425641
963 963 -, c dbSNP:770831565
967 967 a, c dbSNP:76165778
984 984 c, t dbSNP:779552235
1002 1002 c, g dbSNP:9610915
1012 1012 c, t dbSNP:768292078
1029 1029 a, g dbSNP:766072396
1037 1037 c, g dbSNP:371159397
1044 1044 c, g dbSNP:561449558
1077 1077 -, ga dbSNP:748490230
1077 1077 a, g dbSNP:577083647
1152 1152 c, t dbSNP:372303727
1204 1204 c, g dbSNP:771957100
1217 1217 a, g dbSNP:548922128
1220 1220 a, c dbSNP:11544353
1240 1240 c, t dbSNP:767178175
1336 1336 a, g dbSNP:780698495
1398 1398 a, g dbSNP:752233618
1402 1402 a, c dbSNP:756668211
1432 1432 g, t dbSNP:760703540
1452 1452 a, g dbSNP:528357582
1472 1472 a, g dbSNP:778103122
1496 1496 c, t dbSNP:551134407
1497 1497 a, g dbSNP:546493397
1599 1599 a, g dbSNP:571451348
1605 1605 a, g dbSNP:375450672
1608 1608 a, g, t dbSNP:757505099
1615 1615 a, g dbSNP:551090965
1633 1633 a, g dbSNP:181134252
1707 1707 c, g dbSNP:536261716
1716 1716 a, g dbSNP:368460015
1739 1739 -, ct dbSNP:538722754
1754 1754 c, g dbSNP:554903501
1764 1764 a, g dbSNP:573481255
1774 1774 g, t dbSNP:538041092
1794 1794 a, c dbSNP:558764409
1866 1866 a, g dbSNP:148163281
1918 1918 a, t dbSNP:141960079
1924 1924 a, g dbSNP:75078936
1951 1951 a, t dbSNP:1063237
1997 1997 c, g dbSNP:372403046
1998 1998 a, g dbSNP:532544241
2010 2010 c, t dbSNP:186990694
2027 2027 a, g dbSNP:139842666
2030 2030 c, t dbSNP:769779913
2032 2032 c, t dbSNP:775097549
2033 2033 a, g dbSNP:546850487
2053 2053 c, t dbSNP:565121561
2084 2084 a, g dbSNP:376949016
2094 2094 a, g dbSNP:368006761
2133 2133 a, g dbSNP:4821766
2147 2147 c, t dbSNP:762937410
2174 2174 c, t dbSNP:539764956
2258 2258 c, t dbSNP:550756188
2294 2294 a, c dbSNP:5995550
2299 2299 a, g dbSNP:774258642
2329 2329 c, t dbSNP:759313168
2330 2330 a, g dbSNP:556453125
2364 2364 a, c dbSNP:752286710
2369 2369 a, g dbSNP:147366066
2376 2376 c, t dbSNP:566845221
2377 2377 a, g dbSNP:534254189
2392 2392 c, t dbSNP:371972049
2429 2429 a, c dbSNP:3177639
2434 2434 a, g dbSNP:3188073
2438 2438 -, a dbSNP:199817201

Target ORF information:

RefSeq Version NM_012323
Organism Homo sapiens (human)
Definition Homo sapiens v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F (MAFF), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1-C-(k)DYK
NM_012323

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
ATGTCTGTGG ATCCCCTATC CAGCAAAGCT CTAAAGATCA AGCGAGAGCT GAGCGAGAAC 
ACGCCGCACC TGTCGGACGA GGCGCTGATG GGGCTGTCGG TGCGCGAGCT GAACCGGCAT
CTGCGCGGGC TCTCCGCCGA GGAGGTGACA CGGCTCAAGC AGCGGCGCCG CACACTCAAA
AACCGTGGCT ACGCCGCCAG CTGCCGCGTG AAGCGCGTGT GCCAGAAGGA GGAGCTGCAG
AAGCAGAAGT CGGAGCTGGA GCGCGAGGTG GACAAGCTGG CGCGCGAGAA CGCCGCCATG
CGCCTGGAGC TCGACGCGCT GCGCGGCAAG TGCGAGGCGC TGCAGGGCTT CGCGCGCTCC
GTGGCCGCCG CCCGCGGGCC CGCCACGCTC GTGGCGCCGG CCAGCGTCAT CACCATCGTC
AAGTCCACCC CGGGCTCGGG GTCTGGCCCC GCCCACGGCC CGGACCCCGC CCACGGCCCG
GCCTCCTGCT CCTAG

The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.


CloneID OHu31535D
Sequence Information ORF Nucleotide Sequence (Length: 495bp)
Protein sequence
SNP
Vector pcDNA3.1-C-(k)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1-C-(k)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product transcription factor MafF isoform a
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA209378.1, DA654696.1, AK002001.1, DB319587.1, AJ010857.1 and AI610651.1. Summary: The protein encoded by this gene is a basic leucine zipper (bZIP) transcription factor that lacks a transactivation domain. It is known to bind the US-2 DNA element in the promoter of the oxytocin receptor (OTR) gene and most likely heterodimerizes with other leucine zipper-containing proteins to enhance expression of the OTR gene during term pregnancy. The encoded protein can also form homodimers, and since it lacks a transactivation domain, the homodimer may act as a repressor of transcription. This gene may also be involved in the cellular stress response. Multiple transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2009]. Transcript Variant: This variant (3) represents the longest transcript and encodes the longer isoform (a). Variants 1, 3, and 4 encode the same isoform (a). ##Evidence-Data-START## Transcript exon combination :: DA654696.1, DA501043.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2148093, SAMEA2149398 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
ATGTCTGTGG ATCCCCTATC CAGCAAAGCT CTAAAGATCA AGCGAGAGCT GAGCGAGAAC 
ACGCCGCACC TGTCGGACGA GGCGCTGATG GGGCTGTCGG TGCGCGAGCT GAACCGGCAT
CTGCGCGGGC TCTCCGCCGA GGAGGTGACA CGGCTCAAGC AGCGGCGCCG CACACTCAAA
AACCGTGGCT ACGCCGCCAG CTGCCGCGTG AAGCGCGTGT GCCAGAAGGA GGAGCTGCAG
AAGCAGAAGT CGGAGCTGGA GCGCGAGGTG GACAAGCTGG CGCGCGAGAA CGCCGCCATG
CGCCTGGAGC TCGACGCGCT GCGCGGCAAG TGCGAGGCGC TGCAGGGCTT CGCGCGCTCC
GTGGCCGCCG CCCGCGGGCC CGCCACGCTC GTGGCGCCGG CCAGCGTCAT CACCATCGTC
AAGTCCACCC CGGGCTCGGG GTCTGGCCCC GCCCACGGCC CGGACCCCGC CCACGGCCCG
GCCTCCTGCT CCTAG
The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.
RefSeqNP_001155044.1
CDS339..833
Misc Feature(1)249..251(+)
Misc Feature(2)477..683(+)
Misc Feature(3)477..683(+)
Misc Feature(4)489..566(+)
Misc Feature(5)504..554(+)
Misc Feature(6)552..662(+)
Misc Feature(7)573..617(+)
Exon (1)1..307
Gene:MAFF
Gene Synonym:
Exon (2)308..374
Gene:MAFF
Gene Synonym:
Exon (3)375..2466
Gene:MAFF
Gene Synonym:
Translation
Position Chain Variation Link
19 19 a, g dbSNP:550901328
29 29 a, g dbSNP:569048551
87 87 c, g dbSNP:529977800
103 103 c, t dbSNP:11703601
138 138 a, g dbSNP:566644674
156 156 c, g dbSNP:909629
166 166 a, c dbSNP:558760164
242 242 a, g dbSNP:140153593
296 296 a, g dbSNP:2267372
308 308 g, t dbSNP:369326133
309 309 c, t dbSNP:779231199
310 310 c, t dbSNP:746196239
313 313 c, t dbSNP:772508467
321 321 a, t dbSNP:775818328
322 322 g, t dbSNP:761247161
338 338 c, g, t dbSNP:373498296
340 340 c, t dbSNP:762592473
347 347 a, g dbSNP:766108175
354 354 c, g dbSNP:145033364
356 356 a, c dbSNP:759216253
357 357 c, t dbSNP:377667070
368 368 g, t dbSNP:752522153
370 370 c, t dbSNP:140474993
377 377 c, g dbSNP:374499428
379 379 a, c dbSNP:758643505
392 392 a, c dbSNP:780182396
395 395 a, g dbSNP:747356045
400 400 c, t dbSNP:755417006
407 407 c, t dbSNP:539101232
413 413 g, t dbSNP:748674205
416 416 a, c dbSNP:770292607
417 417 a, g dbSNP:773901929
422 422 a, g dbSNP:745433034
425 425 a, g dbSNP:771721927
441 441 a, c dbSNP:775168420
461 461 a, g dbSNP:760410351
462 462 a, c dbSNP:763907616
466 466 g, t dbSNP:776484507
482 482 a, g dbSNP:761751184
485 485 a, g dbSNP:765144379
489 489 c, t dbSNP:750486792
516 516 -, a dbSNP:755031237
517 517 a, g dbSNP:762993702
520 520 a, t dbSNP:766575506
527 527 c, g dbSNP:751863340
533 533 c, t dbSNP:755331154
561 561 c, t dbSNP:781703810
566 566 a, g dbSNP:753173557
578 578 a, g dbSNP:756643749
589 589 c, t dbSNP:367755646
609 609 a, g dbSNP:745357714
617 617 c, g dbSNP:771500797
648 648 c, t dbSNP:779641780
653 653 c, t dbSNP:746668329
693 693 c, t dbSNP:768380103
701 701 a, g dbSNP:776395712
752 752 c, t dbSNP:575686077
756 756 a, g dbSNP:372940204
760 760 a, g dbSNP:537001159
769 769 a, c dbSNP:769751288
771 771 g, t dbSNP:773046312
801 801 a, g dbSNP:375946855
804 804 c, t dbSNP:370305629
843 843 c, t dbSNP:766574334
854 854 c, t dbSNP:554955876
895 895 c, t dbSNP:759821374
953 953 a, g dbSNP:559332974
954 954 c, t dbSNP:767920699
961 961 c, t dbSNP:753077533
965 965 c, t dbSNP:756482362
968 968 a, g dbSNP:188743876
975 975 a, g dbSNP:540474027
981 981 c, g dbSNP:73425641
989 989 -, c dbSNP:770831565
993 993 a, c dbSNP:76165778
1010 1010 c, t dbSNP:779552235
1028 1028 c, g dbSNP:9610915
1038 1038 c, t dbSNP:768292078
1055 1055 a, g dbSNP:766072396
1063 1063 c, g dbSNP:371159397
1070 1070 c, g dbSNP:561449558
1103 1103 -, ga dbSNP:748490230
1103 1103 a, g dbSNP:577083647
1178 1178 c, t dbSNP:372303727
1230 1230 c, g dbSNP:771957100
1243 1243 a, g dbSNP:548922128
1246 1246 a, c dbSNP:11544353
1266 1266 c, t dbSNP:767178175
1362 1362 a, g dbSNP:780698495
1424 1424 a, g dbSNP:752233618
1428 1428 a, c dbSNP:756668211
1458 1458 g, t dbSNP:760703540
1478 1478 a, g dbSNP:528357582
1498 1498 a, g dbSNP:778103122
1522 1522 c, t dbSNP:551134407
1523 1523 a, g dbSNP:546493397
1625 1625 a, g dbSNP:571451348
1631 1631 a, g dbSNP:375450672
1634 1634 a, g, t dbSNP:757505099
1641 1641 a, g dbSNP:551090965
1659 1659 a, g dbSNP:181134252
1733 1733 c, g dbSNP:536261716
1742 1742 a, g dbSNP:368460015
1765 1765 -, ct dbSNP:538722754
1780 1780 c, g dbSNP:554903501
1790 1790 a, g dbSNP:573481255
1800 1800 g, t dbSNP:538041092
1820 1820 a, c dbSNP:558764409
1892 1892 a, g dbSNP:148163281
1944 1944 a, t dbSNP:141960079
1950 1950 a, g dbSNP:75078936
1977 1977 a, t dbSNP:1063237
2023 2023 c, g dbSNP:372403046
2024 2024 a, g dbSNP:532544241
2036 2036 c, t dbSNP:186990694
2053 2053 a, g dbSNP:139842666
2056 2056 c, t dbSNP:769779913
2058 2058 c, t dbSNP:775097549
2059 2059 a, g dbSNP:546850487
2079 2079 c, t dbSNP:565121561
2110 2110 a, g dbSNP:376949016
2120 2120 a, g dbSNP:368006761
2159 2159 a, g dbSNP:4821766
2173 2173 c, t dbSNP:762937410
2200 2200 c, t dbSNP:539764956
2284 2284 c, t dbSNP:550756188
2320 2320 a, c dbSNP:5995550
2325 2325 a, g dbSNP:774258642
2355 2355 c, t dbSNP:759313168
2356 2356 a, g dbSNP:556453125
2390 2390 a, c dbSNP:752286710
2395 2395 a, g dbSNP:147366066
2402 2402 c, t dbSNP:566845221
2403 2403 a, g dbSNP:534254189
2418 2418 c, t dbSNP:371972049
2455 2455 a, c dbSNP:3177639
2460 2460 a, g dbSNP:3188073
2464 2464 -, a dbSNP:199817201

Target ORF information:

RefSeq Version NM_001161572
Organism Homo sapiens (human)
Definition Homo sapiens v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F (MAFF), transcript variant 3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1-C-(k)DYK
NM_001161572

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
ATGTCTGTGG ATCCCCTATC CAGCAAAGCT CTAAAGATCA AGCGAGAGCT GAGCGAGAAC 
ACGCCGCACC TGTCGGACGA GGCGCTGATG GGGCTGTCGG TGCGCGAGCT GAACCGGCAT
CTGCGCGGGC TCTCCGCCGA GGAGGTGACA CGGCTCAAGC AGCGGCGCCG CACACTCAAA
AACCGTGGCT ACGCCGCCAG CTGCCGCGTG AAGCGCGTGT GCCAGAAGGA GGAGCTGCAG
AAGCAGAAGT CGGAGCTGGA GCGCGAGGTG GACAAGCTGG CGCGCGAGAA CGCCGCCATG
CGCCTGGAGC TCGACGCGCT GCGCGGCAAG TGCGAGGCGC TGCAGGGCTT CGCGCGCTCC
GTGGCCGCCG CCCGCGGGCC CGCCACGCTC GTGGCGCCGG CCAGCGTCAT CACCATCGTC
AAGTCCACCC CGGGCTCGGG GTCTGGCCCC GCCCACGGCC CGGACCCCGC CCACGGCCCG
GCCTCCTGCT CCTAG

The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.


CloneID OHu31535D
Sequence Information ORF Nucleotide Sequence (Length: 495bp)
Protein sequence
SNP
Vector pcDNA3.1-C-(k)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1-C-(k)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product transcription factor MafF isoform a
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA425613.1, AK002001.1, DB319587.1, AJ010857.1 and AI610651.1. Summary: The protein encoded by this gene is a basic leucine zipper (bZIP) transcription factor that lacks a transactivation domain. It is known to bind the US-2 DNA element in the promoter of the oxytocin receptor (OTR) gene and most likely heterodimerizes with other leucine zipper-containing proteins to enhance expression of the OTR gene during term pregnancy. The encoded protein can also form homodimers, and since it lacks a transactivation domain, the homodimer may act as a repressor of transcription. This gene may also be involved in the cellular stress response. Multiple transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2009]. Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 3. Variants 1, 3, and 4 encode the same isoform (a). ##Evidence-Data-START## Transcript exon combination :: DA425613.1, DA872919.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
ATGTCTGTGG ATCCCCTATC CAGCAAAGCT CTAAAGATCA AGCGAGAGCT GAGCGAGAAC 
ACGCCGCACC TGTCGGACGA GGCGCTGATG GGGCTGTCGG TGCGCGAGCT GAACCGGCAT
CTGCGCGGGC TCTCCGCCGA GGAGGTGACA CGGCTCAAGC AGCGGCGCCG CACACTCAAA
AACCGTGGCT ACGCCGCCAG CTGCCGCGTG AAGCGCGTGT GCCAGAAGGA GGAGCTGCAG
AAGCAGAAGT CGGAGCTGGA GCGCGAGGTG GACAAGCTGG CGCGCGAGAA CGCCGCCATG
CGCCTGGAGC TCGACGCGCT GCGCGGCAAG TGCGAGGCGC TGCAGGGCTT CGCGCGCTCC
GTGGCCGCCG CCCGCGGGCC CGCCACGCTC GTGGCGCCGG CCAGCGTCAT CACCATCGTC
AAGTCCACCC CGGGCTCGGG GTCTGGCCCC GCCCACGGCC CGGACCCCGC CCACGGCCCG
GCCTCCTGCT CCTAG
The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.
RefSeqNP_001155045.1
CDS97..591
Misc Feature(1)4..6(+)
Misc Feature(2)235..441(+)
Misc Feature(3)235..441(+)
Misc Feature(4)247..324(+)
Misc Feature(5)262..312(+)
Misc Feature(6)310..420(+)
Misc Feature(7)331..375(+)
Exon (1)1..65
Gene:MAFF
Gene Synonym:
Exon (2)66..132
Gene:MAFF
Gene Synonym:
Exon (3)133..2224
Gene:MAFF
Gene Synonym:
Translation
Position Chain Variation Link
7 7 a, g dbSNP:549925954
41 41 a, g dbSNP:745858769
62 62 a, c dbSNP:184544480
66 66 g, t dbSNP:369326133
67 67 c, t dbSNP:779231199
68 68 c, t dbSNP:746196239
71 71 c, t dbSNP:772508467
79 79 a, t dbSNP:775818328
80 80 g, t dbSNP:761247161
96 96 c, g, t dbSNP:373498296
98 98 c, t dbSNP:762592473
105 105 a, g dbSNP:766108175
112 112 c, g dbSNP:145033364
114 114 a, c dbSNP:759216253
115 115 c, t dbSNP:377667070
126 126 g, t dbSNP:752522153
128 128 c, t dbSNP:140474993
135 135 c, g dbSNP:374499428
137 137 a, c dbSNP:758643505
150 150 a, c dbSNP:780182396
153 153 a, g dbSNP:747356045
158 158 c, t dbSNP:755417006
165 165 c, t dbSNP:539101232
171 171 g, t dbSNP:748674205
174 174 a, c dbSNP:770292607
175 175 a, g dbSNP:773901929
180 180 a, g dbSNP:745433034
183 183 a, g dbSNP:771721927
199 199 a, c dbSNP:775168420
219 219 a, g dbSNP:760410351
220 220 a, c dbSNP:763907616
224 224 g, t dbSNP:776484507
240 240 a, g dbSNP:761751184
243 243 a, g dbSNP:765144379
247 247 c, t dbSNP:750486792
274 274 -, a dbSNP:755031237
275 275 a, g dbSNP:762993702
278 278 a, t dbSNP:766575506
285 285 c, g dbSNP:751863340
291 291 c, t dbSNP:755331154
319 319 c, t dbSNP:781703810
324 324 a, g dbSNP:753173557
336 336 a, g dbSNP:756643749
347 347 c, t dbSNP:367755646
367 367 a, g dbSNP:745357714
375 375 c, g dbSNP:771500797
406 406 c, t dbSNP:779641780
411 411 c, t dbSNP:746668329
451 451 c, t dbSNP:768380103
459 459 a, g dbSNP:776395712
510 510 c, t dbSNP:575686077
514 514 a, g dbSNP:372940204
518 518 a, g dbSNP:537001159
527 527 a, c dbSNP:769751288
529 529 g, t dbSNP:773046312
559 559 a, g dbSNP:375946855
562 562 c, t dbSNP:370305629
601 601 c, t dbSNP:766574334
612 612 c, t dbSNP:554955876
653 653 c, t dbSNP:759821374
711 711 a, g dbSNP:559332974
712 712 c, t dbSNP:767920699
719 719 c, t dbSNP:753077533
723 723 c, t dbSNP:756482362
726 726 a, g dbSNP:188743876
733 733 a, g dbSNP:540474027
739 739 c, g dbSNP:73425641
747 747 -, c dbSNP:770831565
751 751 a, c dbSNP:76165778
768 768 c, t dbSNP:779552235
786 786 c, g dbSNP:9610915
796 796 c, t dbSNP:768292078
813 813 a, g dbSNP:766072396
821 821 c, g dbSNP:371159397
828 828 c, g dbSNP:561449558
861 861 -, ga dbSNP:748490230
861 861 a, g dbSNP:577083647
936 936 c, t dbSNP:372303727
988 988 c, g dbSNP:771957100
1001 1001 a, g dbSNP:548922128
1004 1004 a, c dbSNP:11544353
1024 1024 c, t dbSNP:767178175
1120 1120 a, g dbSNP:780698495
1182 1182 a, g dbSNP:752233618
1186 1186 a, c dbSNP:756668211
1216 1216 g, t dbSNP:760703540
1236 1236 a, g dbSNP:528357582
1256 1256 a, g dbSNP:778103122
1280 1280 c, t dbSNP:551134407
1281 1281 a, g dbSNP:546493397
1383 1383 a, g dbSNP:571451348
1389 1389 a, g dbSNP:375450672
1392 1392 a, g, t dbSNP:757505099
1399 1399 a, g dbSNP:551090965
1417 1417 a, g dbSNP:181134252
1491 1491 c, g dbSNP:536261716
1500 1500 a, g dbSNP:368460015
1523 1523 -, ct dbSNP:538722754
1538 1538 c, g dbSNP:554903501
1548 1548 a, g dbSNP:573481255
1558 1558 g, t dbSNP:538041092
1578 1578 a, c dbSNP:558764409
1650 1650 a, g dbSNP:148163281
1702 1702 a, t dbSNP:141960079
1708 1708 a, g dbSNP:75078936
1735 1735 a, t dbSNP:1063237
1781 1781 c, g dbSNP:372403046
1782 1782 a, g dbSNP:532544241
1794 1794 c, t dbSNP:186990694
1811 1811 a, g dbSNP:139842666
1814 1814 c, t dbSNP:769779913
1816 1816 c, t dbSNP:775097549
1817 1817 a, g dbSNP:546850487
1837 1837 c, t dbSNP:565121561
1868 1868 a, g dbSNP:376949016
1878 1878 a, g dbSNP:368006761
1917 1917 a, g dbSNP:4821766
1931 1931 c, t dbSNP:762937410
1958 1958 c, t dbSNP:539764956
2042 2042 c, t dbSNP:550756188
2078 2078 a, c dbSNP:5995550
2083 2083 a, g dbSNP:774258642
2113 2113 c, t dbSNP:759313168
2114 2114 a, g dbSNP:556453125
2148 2148 a, c dbSNP:752286710
2153 2153 a, g dbSNP:147366066
2160 2160 c, t dbSNP:566845221
2161 2161 a, g dbSNP:534254189
2176 2176 c, t dbSNP:371972049
2213 2213 a, c dbSNP:3177639
2218 2218 a, g dbSNP:3188073
2222 2222 -, a dbSNP:199817201

Target ORF information:

RefSeq Version NM_001161573
Organism Homo sapiens (human)
Definition Homo sapiens v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F (MAFF), transcript variant 4, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1-C-(k)DYK
NM_001161573

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
ATGTCTGTGG ATCCCCTATC CAGCAAAGCT CTAAAGATCA AGCGAGAGCT GAGCGAGAAC 
ACGCCGCACC TGTCGGACGA GGCGCTGATG GGGCTGTCGG TGCGCGAGCT GAACCGGCAT
CTGCGCGGGC TCTCCGCCGA GGAGGTGACA CGGCTCAAGC AGCGGCGCCG CACACTCAAA
AACCGTGGCT ACGCCGCCAG CTGCCGCGTG AAGCGCGTGT GCCAGAAGGA GGAGCTGCAG
AAGCAGAAGT CGGAGCTGGA GCGCGAGGTG GACAAGCTGG CGCGCGAGAA CGCCGCCATG
CGCCTGGAGC TCGACGCGCT GCGCGGCAAG TGCGAGGCGC TGCAGGGCTT CGCGCGCTCC
GTGGCCGCCG CCCGCGGGCC CGCCACGCTC GTGGCGCCGG CCAGCGTCAT CACCATCGTC
AAGTCCACCC CGGGCTCGGG GTCTGGCCCC GCCCACGGCC CGGACCCCGC CCACGGCCCG
GCCTCCTGCT CCTAG

The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.


CloneID OHu03210D
Sequence Information ORF Nucleotide Sequence (Length: 408bp)
Protein sequence
SNP
Vector pcDNA3.1-C-(k)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1-C-(k)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product transcription factor MafF isoform b
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA209378.1, AK300932.1, AK002001.1, DB319587.1, AJ010857.1 and AI610651.1. Summary: The protein encoded by this gene is a basic leucine zipper (bZIP) transcription factor that lacks a transactivation domain. It is known to bind the US-2 DNA element in the promoter of the oxytocin receptor (OTR) gene and most likely heterodimerizes with other leucine zipper-containing proteins to enhance expression of the OTR gene during term pregnancy. The encoded protein can also form homodimers, and since it lacks a transactivation domain, the homodimer may act as a repressor of transcription. This gene may also be involved in the cellular stress response. Multiple transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2009]. Transcript Variant: This variant (5) lacks the exon containing the translation start site compared to variant 3. The resulting isoform (b) is shorter at the N-terminus compared to isoform a. ##Evidence-Data-START## Transcript exon combination :: AK300932.1, DC388299.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA962346 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
ATGGGGCTGT CGGTGCGCGA GCTGAACCGG CATCTGCGCG GGCTCTCCGC CGAGGAGGTG 
ACACGGCTCA AGCAGCGGCG CCGCACACTC AAAAACCGTG GCTACGCCGC CAGCTGCCGC
GTGAAGCGCG TGTGCCAGAA GGAGGAGCTG CAGAAGCAGA AGTCGGAGCT GGAGCGCGAG
GTGGACAAGC TGGCGCGCGA GAACGCCGCC ATGCGCCTGG AGCTCGACGC GCTGCGCGGC
AAGTGCGAGG CGCTGCAGGG CTTCGCGCGC TCCGTGGCCG CCGCCCGCGG GCCCGCCACG
CTCGTGGCGC CGGCCAGCGT CATCACCATC GTCAAGTCCA CCCCGGGCTC GGGGTCTGGC
CCCGCCCACG GCCCGGACCC CGCCCACGGC CCGGCCTCCT GCTCCTAG
The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.
RefSeqNP_001155046.1
CDS333..740
Misc Feature(1)249..251(+)
Misc Feature(2)384..590(+)
Misc Feature(3)384..590(+)
Misc Feature(4)411..461(+)
Misc Feature(5)459..569(+)
Exon (1)1..281
Gene:MAFF
Gene Synonym:
Exon (2)282..2373
Gene:MAFF
Gene Synonym:
Translation
Position Chain Variation Link
19 19 a, g dbSNP:550901328
29 29 a, g dbSNP:569048551
87 87 c, g dbSNP:529977800
103 103 c, t dbSNP:11703601
138 138 a, g dbSNP:566644674
156 156 c, g dbSNP:909629
166 166 a, c dbSNP:558760164
242 242 a, g dbSNP:140153593
284 284 c, g dbSNP:374499428
286 286 a, c dbSNP:758643505
299 299 a, c dbSNP:780182396
302 302 a, g dbSNP:747356045
307 307 c, t dbSNP:755417006
314 314 c, t dbSNP:539101232
320 320 g, t dbSNP:748674205
323 323 a, c dbSNP:770292607
324 324 a, g dbSNP:773901929
329 329 a, g dbSNP:745433034
332 332 a, g dbSNP:771721927
348 348 a, c dbSNP:775168420
368 368 a, g dbSNP:760410351
369 369 a, c dbSNP:763907616
373 373 g, t dbSNP:776484507
389 389 a, g dbSNP:761751184
392 392 a, g dbSNP:765144379
396 396 c, t dbSNP:750486792
423 423 -, a dbSNP:755031237
424 424 a, g dbSNP:762993702
427 427 a, t dbSNP:766575506
434 434 c, g dbSNP:751863340
440 440 c, t dbSNP:755331154
468 468 c, t dbSNP:781703810
473 473 a, g dbSNP:753173557
485 485 a, g dbSNP:756643749
496 496 c, t dbSNP:367755646
516 516 a, g dbSNP:745357714
524 524 c, g dbSNP:771500797
555 555 c, t dbSNP:779641780
560 560 c, t dbSNP:746668329
600 600 c, t dbSNP:768380103
608 608 a, g dbSNP:776395712
659 659 c, t dbSNP:575686077
663 663 a, g dbSNP:372940204
667 667 a, g dbSNP:537001159
676 676 a, c dbSNP:769751288
678 678 g, t dbSNP:773046312
708 708 a, g dbSNP:375946855
711 711 c, t dbSNP:370305629
750 750 c, t dbSNP:766574334
761 761 c, t dbSNP:554955876
802 802 c, t dbSNP:759821374
860 860 a, g dbSNP:559332974
861 861 c, t dbSNP:767920699
868 868 c, t dbSNP:753077533
872 872 c, t dbSNP:756482362
875 875 a, g dbSNP:188743876
882 882 a, g dbSNP:540474027
888 888 c, g dbSNP:73425641
896 896 -, c dbSNP:770831565
900 900 a, c dbSNP:76165778
917 917 c, t dbSNP:779552235
935 935 c, g dbSNP:9610915
945 945 c, t dbSNP:768292078
962 962 a, g dbSNP:766072396
970 970 c, g dbSNP:371159397
977 977 c, g dbSNP:561449558
1010 1010 -, ga dbSNP:748490230
1010 1010 a, g dbSNP:577083647
1085 1085 c, t dbSNP:372303727
1137 1137 c, g dbSNP:771957100
1150 1150 a, g dbSNP:548922128
1153 1153 a, c dbSNP:11544353
1173 1173 c, t dbSNP:767178175
1269 1269 a, g dbSNP:780698495
1331 1331 a, g dbSNP:752233618
1335 1335 a, c dbSNP:756668211
1365 1365 g, t dbSNP:760703540
1385 1385 a, g dbSNP:528357582
1405 1405 a, g dbSNP:778103122
1429 1429 c, t dbSNP:551134407
1430 1430 a, g dbSNP:546493397
1532 1532 a, g dbSNP:571451348
1538 1538 a, g dbSNP:375450672
1541 1541 a, g, t dbSNP:757505099
1548 1548 a, g dbSNP:551090965
1566 1566 a, g dbSNP:181134252
1640 1640 c, g dbSNP:536261716
1649 1649 a, g dbSNP:368460015
1672 1672 -, ct dbSNP:538722754
1687 1687 c, g dbSNP:554903501
1697 1697 a, g dbSNP:573481255
1707 1707 g, t dbSNP:538041092
1727 1727 a, c dbSNP:558764409
1799 1799 a, g dbSNP:148163281
1851 1851 a, t dbSNP:141960079
1857 1857 a, g dbSNP:75078936
1884 1884 a, t dbSNP:1063237
1930 1930 c, g dbSNP:372403046
1931 1931 a, g dbSNP:532544241
1943 1943 c, t dbSNP:186990694
1960 1960 a, g dbSNP:139842666
1963 1963 c, t dbSNP:769779913
1965 1965 c, t dbSNP:775097549
1966 1966 a, g dbSNP:546850487
1986 1986 c, t dbSNP:565121561
2017 2017 a, g dbSNP:376949016
2027 2027 a, g dbSNP:368006761
2066 2066 a, g dbSNP:4821766
2080 2080 c, t dbSNP:762937410
2107 2107 c, t dbSNP:539764956
2191 2191 c, t dbSNP:550756188
2227 2227 a, c dbSNP:5995550
2232 2232 a, g dbSNP:774258642
2262 2262 c, t dbSNP:759313168
2263 2263 a, g dbSNP:556453125
2297 2297 a, c dbSNP:752286710
2302 2302 a, g dbSNP:147366066
2309 2309 c, t dbSNP:566845221
2310 2310 a, g dbSNP:534254189
2325 2325 c, t dbSNP:371972049
2362 2362 a, c dbSNP:3177639
2367 2367 a, g dbSNP:3188073
2371 2371 -, a dbSNP:199817201

Target ORF information:

RefSeq Version NM_001161574
Organism Homo sapiens (human)
Definition Homo sapiens v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F (MAFF), transcript variant 5, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1-C-(k)DYK
NM_001161574

ORF Insert Sequence:

1
61
121
181
241
301
361
ATGGGGCTGT CGGTGCGCGA GCTGAACCGG CATCTGCGCG GGCTCTCCGC CGAGGAGGTG 
ACACGGCTCA AGCAGCGGCG CCGCACACTC AAAAACCGTG GCTACGCCGC CAGCTGCCGC
GTGAAGCGCG TGTGCCAGAA GGAGGAGCTG CAGAAGCAGA AGTCGGAGCT GGAGCGCGAG
GTGGACAAGC TGGCGCGCGA GAACGCCGCC ATGCGCCTGG AGCTCGACGC GCTGCGCGGC
AAGTGCGAGG CGCTGCAGGG CTTCGCGCGC TCCGTGGCCG CCGCCCGCGG GCCCGCCACG
CTCGTGGCGC CGGCCAGCGT CATCACCATC GTCAAGTCCA CCCCGGGCTC GGGGTCTGGC
CCCGCCCACG GCCCGGACCC CGCCCACGGC CCGGCCTCCT GCTCCTAG

The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.