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ALPL cDNA ORF clone, Homo sapiens (human)

Gene Symbol ALPL
Entrez Gene ID 249
Full Name alkaline phosphatase, liver/bone/kidney
Synonyms AP-TNAP, APTNAP, HOPS, TNAP, TNSALP
General protein information
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

1

1p36.12

Summary There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization; however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to hypophosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of this disorder can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms. Alternatively spliced transcript variants have been described. [provided by RefSeq, Apr 2010]. lac of sum
Disorder MIM:

171760

Disorder Html: Hypophosphatasia, infantile, 241500 (3); Hypophosphatasia, childhood,





The following ALPL gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ALPL cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu33310 XM_006710546 PREDICTED: Homo sapiens alkaline phosphatase, liver/bone/kidney (ALPL), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $439.00
OHu33310 XM_005245818 PREDICTED: Homo sapiens alkaline phosphatase, liver/bone/kidney (ALPL), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $439.00
OHu33311 XM_005245820 PREDICTED: Homo sapiens alkaline phosphatase, liver/bone/kidney (ALPL), transcript variant X3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $319.00
OHu22555 NM_001127501 Homo sapiens alkaline phosphatase, liver/bone/kidney (ALPL), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $379.00
OHu23043 NM_001177520 Homo sapiens alkaline phosphatase, liver/bone/kidney (ALPL), transcript variant 3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $379.00
OHu23066 NM_000478 Homo sapiens alkaline phosphatase, liver/bone/kidney (ALPL), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $379.00

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu33310
Accession Version XM_006710546.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1575bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product alkaline phosphatase, tissue-nonspecific isozyme isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_032977.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
ATGATTTCAC CATTCTTAGT ACTGGCCATT GGCACCTGCC TTACTAACTC CTTAGTGCCA 
GAGAAAGAGA AAGACCCCAA GTACTGGCGA GACCAAGCGC AAGAGACACT GAAATATGCC
CTGGAGCTTC AGAAGCTCAA CACCAACGTG GCTAAGAATG TCATCATGTT CCTGGGAGAT
GGGATGGGTG TCTCCACAGT GACGGCTGCC CGCATCCTCA AGGGTCAGCT CCACCACAAC
CCTGGGGAGG AGACCAGGCT GGAGATGGAC AAGTTCCCCT TCGTGGCCCT CTCCAAGACG
TACAACACCA ATGCCCAGGT CCCTGACAGT GCCGGCACCG CCACCGCCTA CCTGTGTGGG
GTGAAGGCCA ATGAGGGCAC CGTGGGGGTA AGCGCAGCCA CTGAGCGTTC CCGGTGCAAC
ACCACCCAGG GGAACGAGGT CACCTCCATC CTGCGCTGGG CCAAGGACGC TGGGAAATCT
GTGGGCATTG TGACCACCAC GAGAGTGAAC CATGCCACCC CCAGCGCCGC CTACGCCCAC
TCGGCTGACC GGGACTGGTA CTCAGACAAC GAGATGCCCC CTGAGGCCTT GAGCCAGGGC
TGTAAGGACA TCGCCTACCA GCTCATGCAT AACATCAGGG ACATTGACGT GATCATGGGG
GGTGGCCGGA AATACATGTA CCCCAAGAAT AAAACTGATG TGGAGTATGA GAGTGACGAG
AAAGCCAGGG GCACGAGGCT GGACGGCCTG GACCTCGTTG ACACCTGGAA GAGCTTCAAA
CCGAGATACA AGCACTCCCA CTTCATCTGG AACCGCACGG AACTCCTGAC CCTTGACCCC
CACAATGTGG ACTACCTATT GGGTCTCTTC GAGCCAGGGG ACATGCAGTA CGAGCTGAAC
AGGAACAACG TGACGGACCC GTCACTCTCC GAGATGGTGG TGGTGGCCAT CCAGATCCTG
CGGAAGAACC CCAAAGGCTT CTTCTTGCTG GTGGAAGGAG GCAGAATTGA CCACGGGCAC
CATGAAGGAA AAGCCAAGCA GGCCCTGCAT GAGGCGGTGG AGATGGACCG GGCCATCGGG
CAGGCAGGCA GCTTGACCTC CTCGGAAGAC ACTCTGACCG TGGTCACTGC GGACCATTCC
CACGTCTTCA CATTTGGTGG ATACACCCCC CGTGGCAACT CTATCTTTGG TCTGGCCCCC
ATGCTGAGTG ACACAGACAA GAAGCCCTTC ACTGCCATCC TGTATGGCAA TGGGCCTGGC
TACAAGGTGG TGGGCGGTGA ACGAGAGAAT GTCTCCATGG TGGACTATGC TCACAACAAC
TACCAGGCGC AGTCTGCTGT GCCCCTGCGC CACGAGACCC ACGGCGGGGA GGACGTGGCC
GTCTTCTCCA AGGGCCCCAT GGCGCACCTG CTGCACGGCG TCCACGAGCA GAACTACGTC
CCCCACGTGA TGGCGTATGC AGCCTGCATC GGGGCCAACC TCGGCCACTG TGCTCCTGCC
AGCTCGGCAG GCAGCCTTGC TGCAGGCCCC CTGCTGCTCG CGCTGGCCCT CTACCCCCTG
AGCGTCCTGT TCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqXP_006710609.1
CDS220..1794
Misc Feature(1)355..1689(+)
Misc Feature(2)355..1665(+)
Misc Feature(3)397..1581(+)
Translation
Position Chain Variation Link
54 54 g, t dbSNP:552293218
93 93 a, c dbSNP:547353454
102 102 c, g dbSNP:565901572
112 112 a, g dbSNP:753433184
139 139 a, g dbSNP:528218843
167 167 a, c dbSNP:540299799
169 169 c, t dbSNP:753110554
170 170 a, g dbSNP:756589854
172 172 c, t dbSNP:201284200
173 173 a, g dbSNP:749996516
177 177 a, g, t dbSNP:371685734
189 189 g, t dbSNP:746531325
194 194 a, g dbSNP:754895943
205 205 g, t dbSNP:781172426
206 206 c, t dbSNP:747906165
212 212 a, g dbSNP:769524226
218 218 a, c dbSNP:773092184
223 223 a, g dbSNP:776442538
228 228 a, t dbSNP:749406361
231 231 a, g dbSNP:771198723
241 241 c, t dbSNP:774559268
244 244 g, t dbSNP:759760207
245 245 c, t dbSNP:772679576
259 259 c, t dbSNP:139214514
263 263 c, g dbSNP:150849772
292 292 a, g dbSNP:766948855
297 297 c, t dbSNP:375342528
299 299 a, g dbSNP:146412299
303 303 c, t dbSNP:144632001
308 308 a, g dbSNP:753550135
310 310 a, g dbSNP:757127456
317 317 c, g, t dbSNP:121918005
318 318 a, g dbSNP:772424729
320 320 a, g dbSNP:780221572
325 325 a, g dbSNP:747167000
326 326 c, t dbSNP:199952414
329 329 c, t dbSNP:143358506
330 330 a, g dbSNP:769035516
335 335 a, g dbSNP:777235122
336 336 c, t dbSNP:748438719
338 338 c, t dbSNP:770093969
346 346 c, t dbSNP:148357203
347 347 -, t dbSNP:763244290
366 366 a, c, t dbSNP:539884496
367 367 a, g dbSNP:767216554
378 378 a, t dbSNP:774859071
380 380 -, tca dbSNP:766831104
385 385 a, g dbSNP:760272172
389 389 a, t dbSNP:763919659
390 390 c, t dbSNP:753763521
393 393 a, g dbSNP:757176737
423 423 a, g dbSNP:537814225
427 427 a, g dbSNP:147116628
430 430 a, c, t dbSNP:121918001
431 431 c, g dbSNP:121918003
434 434 c, t dbSNP:781264043
440 440 a, g dbSNP:143885304
459 459 a, c dbSNP:756611513
478 478 c, t dbSNP:778292875
483 483 a, g dbSNP:749630641
486 486 a, g dbSNP:771240396
489 489 c, g dbSNP:779180929
501 501 c, t dbSNP:746608270
502 502 a, g dbSNP:139811782
519 519 a, g dbSNP:191778470
522 522 a, c dbSNP:746273959
526 526 a, g dbSNP:202075854
533 533 c, t dbSNP:768348242
542 542 c, t dbSNP:121918015
549 549 -, tgccggcac dbSNP:200166222
549 549 c, t dbSNP:1780316
550 550 a, g dbSNP:773257111
552 552 c, t dbSNP:769379537
558 558 c, t dbSNP:377453516
560 560 c, t dbSNP:762915678
564 564 c, t dbSNP:770785345
565 565 a, g dbSNP:121918013
575 575 c, g dbSNP:774193109
577 577 -, gg dbSNP:751994699
588 588 a, c dbSNP:201342272
590 590 a, g dbSNP:11586344
594 594 a, g dbSNP:752868525
599 599 a, c dbSNP:146517700
600 600 c, t dbSNP:368714904
603 603 c, g dbSNP:764097939
607 607 a, g dbSNP:753929700
613 613 a, g dbSNP:757771793
617 617 c, g dbSNP:184095519
618 618 c, t dbSNP:750766317
619 619 ac, ca dbSNP:786204530
619 619 a, c dbSNP:758734017
620 620 a, c dbSNP:780583917
625 625 a, c, t dbSNP:747762186
626 626 a, g dbSNP:121918011
631 631 c, t dbSNP:748874853
632 632 a, g dbSNP:140167865
639 639 c, t dbSNP:148982201
644 644 -, c dbSNP:760134827
644 644 c, t dbSNP:745841670
645 645 c, t dbSNP:771727704
651 651 a, g dbSNP:775273192
655 655 a, g dbSNP:138587317
672 672 a, g dbSNP:377693871
673 673 c, t dbSNP:200621180
674 674 a, g dbSNP:149344982
675 675 c, t dbSNP:527613008
678 678 a, g dbSNP:761836226
687 687 c, t dbSNP:143621566
688 688 a, g dbSNP:750842585
703 703 a, g dbSNP:760029254
704 704 g, t dbSNP:121918012
711 711 a, g dbSNP:750079676
713 713 c, t dbSNP:753392973
729 729 c, t dbSNP:373912990
731 731 a, g dbSNP:778232217
737 737 -, c dbSNP:750174638
744 744 c, t dbSNP:766504809
745 745 a, g dbSNP:121918019
747 747 c, t dbSNP:758330265
748 748 a, g dbSNP:199669988
750 750 c, g dbSNP:746782435
753 753 c, g, t dbSNP:201250289
754 754 a, g dbSNP:121918000
755 755 c, t dbSNP:748250829
759 759 c, t dbSNP:770068340
761 761 c, t dbSNP:199590449
769 769 c, t dbSNP:763159520
780 780 c, t dbSNP:771542770
783 783 a, t dbSNP:774949653
789 789 c, g, t dbSNP:760153868
790 790 a, g dbSNP:121918007
793 793 a, g dbSNP:761361696
794 794 c, t dbSNP:765011829
796 796 -, c dbSNP:758124823
801 801 c, t dbSNP:112063292
825 825 a, g dbSNP:200597048
829 829 a, t dbSNP:374558572
831 831 c, t dbSNP:141448778
832 832 a, g dbSNP:751455369
834 834 c, t dbSNP:754911877
836 836 a, c dbSNP:780790767
839 839 a, c dbSNP:121918004
848 848 a, g dbSNP:748031071
862 862 a, g dbSNP:769903299
867 867 c, t dbSNP:201739155
868 868 -, c dbSNP:781213038
869 869 -, aa dbSNP:748254075
869 869 c, t dbSNP:777699004
872 872 a, t dbSNP:746014071
874 874 a, g dbSNP:772432010
876 876 -, g dbSNP:769948289
876 876 g, t dbSNP:776117933
877 877 a, g dbSNP:747488546
880 880 c, g dbSNP:769020799
881 881 c, g, t dbSNP:566317085
886 886 c, t dbSNP:766076920
887 887 a, g dbSNP:199665722
892 892 c, t dbSNP:759125473
895 895 a, c dbSNP:767334437
896 896 c, t dbSNP:752641050
903 903 c, t dbSNP:369550359
906 906 g, t dbSNP:763892146
910 910 a, g dbSNP:746933644
911 911 a, g dbSNP:757551727
920 920 c, t dbSNP:779322468
921 921 g, t dbSNP:745924139
925 925 c, t dbSNP:758451024
926 926 a, g dbSNP:533959092
936 936 c, t dbSNP:780024242
946 946 a, c dbSNP:747480886
953 953 c, t dbSNP:142608957
954 954 a, g dbSNP:776965688
963 963 c, t dbSNP:188689330
964 964 a, g dbSNP:770539523
965 965 c, g, t dbSNP:121918018
970 970 a, g dbSNP:781403334
976 976 a, c, g dbSNP:151270365
977 977 a, t dbSNP:774877541
987 987 a, g dbSNP:760649979
992 992 a, g dbSNP:764197078
993 993 c, t dbSNP:753656794
1000 1000 a, c dbSNP:761753019
1001 1001 a, c, t dbSNP:765149569
1002 1002 a, g dbSNP:537483743
1006 1006 c, t dbSNP:3200254
1010 1010 a, g dbSNP:786204442
1021 1021 c, t dbSNP:751625937
1028 1028 a, g dbSNP:786204634
1033 1033 c, t dbSNP:121918020
1034 1034 a, g, t dbSNP:781272386
1037 1037 c, t dbSNP:148405563
1038 1038 a, g dbSNP:372247799
1040 1040 -, a dbSNP:771175614
1042 1042 c, g dbSNP:749684443
1057 1057 a, c dbSNP:771727865
1065 1065 c, t dbSNP:779625059
1069 1069 c, g dbSNP:746700357
1077 1077 a, g dbSNP:375027534
1078 1078 c, t dbSNP:141742288
1083 1083 c, t dbSNP:754262699
1089 1089 c, t dbSNP:779115195
1090 1090 a, g dbSNP:786204473
1093 1093 a, c, t dbSNP:765458125
1095 1095 a, g dbSNP:3200255
1100 1100 a, c dbSNP:121918002
1106 1106 a, t dbSNP:747637927
1110 1110 a, c dbSNP:755529290
1111 1111 a, g dbSNP:121918017
1121 1121 -, g dbSNP:768160006
1122 1122 a, g dbSNP:749112407
1125 1125 a, c, g dbSNP:560308330
1129 1129 a, g dbSNP:745704006
1133 1133 c, t dbSNP:146908399
1134 1134 a, g dbSNP:527465409
1137 1137 c, t dbSNP:373257447
1139 1139 c, t dbSNP:768555495
1142 1142 a, c, t dbSNP:376221105
1146 1146 c, t dbSNP:762210096
1147 1147 a, t dbSNP:765836269
1149 1149 c, t dbSNP:750783677
1150 1150 a, g dbSNP:763457259
1154 1154 -, tgg dbSNP:756329108
1156 1156 c, g dbSNP:552250079
1171 1171 a, c dbSNP:752356218
1177 1177 c, g dbSNP:755795919
1180 1180 c, t dbSNP:200133602
1181 1181 a, g dbSNP:138679161
1182 1182 a, g dbSNP:757111696
1185 1185 a, g dbSNP:778873231
1196 1196 g, t dbSNP:745830614
1197 1197 -, ctt dbSNP:753338851
1198 1198 c, t dbSNP:121918010
1199 1199 g, t dbSNP:779832611
1209 1209 a, g dbSNP:747146797
1213 1213 a, g dbSNP:768976020
1219 1219 a, g dbSNP:769955594
1220 1220 a, g dbSNP:121918009
1221 1221 c, t dbSNP:370122334
1233 1233 -, g dbSNP:764908423
1233 1233 c, t dbSNP:147688908
1238 1238 a, t dbSNP:763800165
1266 1266 g, t dbSNP:771632536
1275 1275 a, g, t dbSNP:774824768
1287 1287 c, g dbSNP:767794155
1288 1288 c, t dbSNP:776304194
1289 1289 a, g dbSNP:202022405
1296 1296 c, t dbSNP:567349821
1297 1297 a, g dbSNP:749989499
1320 1320 c, t dbSNP:758332051
1322 1322 c, t dbSNP:368809478
1331 1331 c, t dbSNP:751292739
1335 1335 c, g dbSNP:200153944
1338 1338 c, t dbSNP:112335417
1339 1339 a, g dbSNP:552831415
1341 1341 a, g dbSNP:748337342
1349 1349 c, t dbSNP:756418235
1350 1350 a, g dbSNP:777986840
1352 1352 a, t dbSNP:121918008
1358 1358 -, c dbSNP:758119185
1362 1362 c, t dbSNP:749419329
1363 1363 a, g dbSNP:771540767
1378 1378 a, g dbSNP:150594290
1384 1384 -, c dbSNP:751404811
1384 1384 a, g dbSNP:774870859
1385 1385 a, c dbSNP:746390776
1385 1385 -, c dbSNP:779683021
1386 1386 c, t dbSNP:772412576
1390 1390 c, t dbSNP:371243939
1395 1395 c, g dbSNP:375767924
1400 1400 -, t dbSNP:754826836
1401 1401 c, t dbSNP:764940488
1402 1402 a, g dbSNP:772682471
1403 1403 c, t dbSNP:751977466
1416 1416 c, t dbSNP:764010876
1420 1420 a, c dbSNP:754044587
1427 1427 a, c, g dbSNP:757564264
1446 1446 c, t dbSNP:750530891
1452 1452 c, t dbSNP:758911741
1453 1453 g, t dbSNP:780478066
1464 1464 c, t dbSNP:747539132
1469 1469 a, g dbSNP:121918014
1482 1482 c, t dbSNP:780762265
1493 1493 a, g dbSNP:781543452
1494 1494 c, t dbSNP:748883680
1495 1495 a, g dbSNP:770548228
1499 1499 a, c dbSNP:773907984
1501 1501 c, t dbSNP:759017288
1509 1509 c, t dbSNP:200330153
1522 1522 c, g dbSNP:771633915
1525 1525 c, t dbSNP:121918006
1527 1527 c, t dbSNP:775526490
1532 1532 -, aca dbSNP:771212957
1533 1533 c, t dbSNP:757045880
1535 1535 a, g dbSNP:368408859
1547 1547 a, c, g dbSNP:768053120
1548 1548 a, g dbSNP:756394364
1567 1567 c, t dbSNP:138690664
1568 1568 a, g dbSNP:150799088
1570 1570 c, t dbSNP:758125155
1572 1572 c, t dbSNP:377110098
1577 1577 -, c dbSNP:774529894
1581 1581 c, t dbSNP:746554462
1582 1582 a, g dbSNP:149889416
1584 1584 c, t dbSNP:370212283
1585 1585 a, g dbSNP:121918016
1585 1585 -, g dbSNP:746256993
1593 1593 c, t dbSNP:776664499
1599 1599 c, t dbSNP:371984578
1600 1600 a, g dbSNP:34810399
1616 1616 c, g dbSNP:773075737
1619 1619 c, t dbSNP:763073466
1622 1622 c, t dbSNP:766656419
1623 1623 a, g dbSNP:774384124
1625 1625 a, g dbSNP:759662331
1627 1627 c, t dbSNP:767614891
1635 1635 c, t dbSNP:369433931
1638 1638 a, c, t dbSNP:373417343
1639 1639 a, g dbSNP:376354718
1641 1641 c, t dbSNP:12027316
1644 1644 c, t dbSNP:183381346
1656 1656 c, t dbSNP:527657489
1659 1659 c, t dbSNP:540139632
1660 1660 c, t dbSNP:754502257
1663 1663 a, c dbSNP:780857373
1665 1665 c, t dbSNP:747980975
1667 1667 c, t dbSNP:769829312
1674 1674 a, g dbSNP:188443578
1683 1683 c, t dbSNP:749148162
1689 1689 c, t dbSNP:771120248
1695 1695 c, t dbSNP:774516408
1698 1698 c, t dbSNP:759758484
1699 1699 c, t dbSNP:772080508
1701 1701 c, t dbSNP:142545037
1702 1702 a, c, g dbSNP:761079751
1711 1711 a, g dbSNP:754125867
1717 1717 a, g dbSNP:762216748
1724 1724 c, t dbSNP:550358395
1725 1725 a, g dbSNP:751195005
1734 1734 a, c dbSNP:754694335
1745 1745 a, g, t dbSNP:79250591
1747 1747 c, t dbSNP:752320340
1750 1750 c, t dbSNP:755976886
1758 1758 c, t dbSNP:529786148
1759 1759 a, g dbSNP:367657406
1760 1760 c, t dbSNP:371373128
1761 1761 a, g, t dbSNP:3200256
1765 1765 a, g dbSNP:772346350
1774 1774 c, g, t dbSNP:775398905
1776 1776 a, c, g, t dbSNP:376020180
1778 1778 -, t dbSNP:387906525
1779 1779 a, g dbSNP:765641649
1781 1781 a, g dbSNP:368326384
1782 1782 c, g dbSNP:370978556
1783 1783 a, g dbSNP:372315234
1784 1784 c, t dbSNP:34605986
1793 1793 -, g dbSNP:764994176
1797 1797 g, t dbSNP:755602034
1799 1799 c, g dbSNP:763515495
1801 1801 a, g dbSNP:753716865
1805 1805 c, t dbSNP:757240883
1806 1806 c, t dbSNP:778673244
1807 1807 c, t dbSNP:559330654
1808 1808 a, g dbSNP:571140206
1811 1811 c, t dbSNP:780269910
1814 1814 c, t dbSNP:567336093
1819 1819 a, t dbSNP:747222706
1820 1820 a, g dbSNP:375281601
1823 1823 c, t dbSNP:768718338
1835 1835 c, t dbSNP:776868579
1837 1837 a, g dbSNP:748654072
1845 1845 a, c dbSNP:770493812
1854 1854 c, g dbSNP:367637559
1858 1858 a, c, g dbSNP:565251838
1859 1859 a, c, t dbSNP:1697405
1860 1860 a, c dbSNP:78043671
1860 1860 -, c dbSNP:371832452
1916 1916 -, c dbSNP:140511985
1917 1917 c, t dbSNP:553947949
1920 1920 a, g dbSNP:1697406
1936 1936 c, t dbSNP:545776624
1937 1937 g, t dbSNP:766588843
1943 1943 c, t dbSNP:564863879
1945 1945 c, t dbSNP:532269853
1972 1972 a, g dbSNP:776773091
1998 1998 c, t dbSNP:116162120
2011 2011 c, t dbSNP:373909118
2012 2012 a, g dbSNP:529801718
2027 2027 a, c dbSNP:1772719
2052 2052 c, t dbSNP:765353111
2055 2055 a, c dbSNP:751503180
2056 2056 c, g dbSNP:566407347
2066 2066 g, t dbSNP:527314874
2070 2070 g, t dbSNP:552201420
2081 2081 a, g dbSNP:757243859
2099 2099 c, t dbSNP:76073898
2114 2114 a, g dbSNP:750252193
2131 2131 a, g dbSNP:538549134
2156 2156 a, g dbSNP:556534930
2182 2182 c, t dbSNP:2242420
2195 2195 -, ctc dbSNP:531742327
2227 2227 a, g dbSNP:2242421
2254 2254 a, g dbSNP:114552089
2267 2267 g, t dbSNP:536009840
2274 2274 a, c dbSNP:138564953
2342 2342 c, t dbSNP:754489263
2369 2369 c, t dbSNP:141554698
2382 2382 a, g dbSNP:778461715
2388 2388 a, g dbSNP:747561664
2431 2431 a, g dbSNP:111947234
2457 2457 c, g dbSNP:145193027
2474 2474 a, g dbSNP:562609652
2479 2479 -, t dbSNP:200291738
2479 2479 a, t dbSNP:78801483
2486 2486 c, t dbSNP:541640914
2491 2491 c, t dbSNP:41265991
2496 2496 -, tgg dbSNP:769940109
2543 2543 a, c dbSNP:139022638

Target ORF information:

RefSeq Version XM_006710546
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens alkaline phosphatase, liver/bone/kidney (ALPL), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_006710546

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
ATGATTTCAC CATTCTTAGT ACTGGCCATT GGCACCTGCC TTACTAACTC CTTAGTGCCA 
GAGAAAGAGA AAGACCCCAA GTACTGGCGA GACCAAGCGC AAGAGACACT GAAATATGCC
CTGGAGCTTC AGAAGCTCAA CACCAACGTG GCTAAGAATG TCATCATGTT CCTGGGAGAT
GGGATGGGTG TCTCCACAGT GACGGCTGCC CGCATCCTCA AGGGTCAGCT CCACCACAAC
CCTGGGGAGG AGACCAGGCT GGAGATGGAC AAGTTCCCCT TCGTGGCCCT CTCCAAGACG
TACAACACCA ATGCCCAGGT CCCTGACAGT GCCGGCACCG CCACCGCCTA CCTGTGTGGG
GTGAAGGCCA ATGAGGGCAC CGTGGGGGTA AGCGCAGCCA CTGAGCGTTC CCGGTGCAAC
ACCACCCAGG GGAACGAGGT CACCTCCATC CTGCGCTGGG CCAAGGACGC TGGGAAATCT
GTGGGCATTG TGACCACCAC GAGAGTGAAC CATGCCACCC CCAGCGCCGC CTACGCCCAC
TCGGCTGACC GGGACTGGTA CTCAGACAAC GAGATGCCCC CTGAGGCCTT GAGCCAGGGC
TGTAAGGACA TCGCCTACCA GCTCATGCAT AACATCAGGG ACATTGACGT GATCATGGGG
GGTGGCCGGA AATACATGTA CCCCAAGAAT AAAACTGATG TGGAGTATGA GAGTGACGAG
AAAGCCAGGG GCACGAGGCT GGACGGCCTG GACCTCGTTG ACACCTGGAA GAGCTTCAAA
CCGAGATACA AGCACTCCCA CTTCATCTGG AACCGCACGG AACTCCTGAC CCTTGACCCC
CACAATGTGG ACTACCTATT GGGTCTCTTC GAGCCAGGGG ACATGCAGTA CGAGCTGAAC
AGGAACAACG TGACGGACCC GTCACTCTCC GAGATGGTGG TGGTGGCCAT CCAGATCCTG
CGGAAGAACC CCAAAGGCTT CTTCTTGCTG GTGGAAGGAG GCAGAATTGA CCACGGGCAC
CATGAAGGAA AAGCCAAGCA GGCCCTGCAT GAGGCGGTGG AGATGGACCG GGCCATCGGG
CAGGCAGGCA GCTTGACCTC CTCGGAAGAC ACTCTGACCG TGGTCACTGC GGACCATTCC
CACGTCTTCA CATTTGGTGG ATACACCCCC CGTGGCAACT CTATCTTTGG TCTGGCCCCC
ATGCTGAGTG ACACAGACAA GAAGCCCTTC ACTGCCATCC TGTATGGCAA TGGGCCTGGC
TACAAGGTGG TGGGCGGTGA ACGAGAGAAT GTCTCCATGG TGGACTATGC TCACAACAAC
TACCAGGCGC AGTCTGCTGT GCCCCTGCGC CACGAGACCC ACGGCGGGGA GGACGTGGCC
GTCTTCTCCA AGGGCCCCAT GGCGCACCTG CTGCACGGCG TCCACGAGCA GAACTACGTC
CCCCACGTGA TGGCGTATGC AGCCTGCATC GGGGCCAACC TCGGCCACTG TGCTCCTGCC
AGCTCGGCAG GCAGCCTTGC TGCAGGCCCC CTGCTGCTCG CGCTGGCCCT CTACCCCCTG
AGCGTCCTGT TCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu33310
Accession Version XM_005245818.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1575bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product alkaline phosphatase, tissue-nonspecific isozyme isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_032977.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
ATGATTTCAC CATTCTTAGT ACTGGCCATT GGCACCTGCC TTACTAACTC CTTAGTGCCA 
GAGAAAGAGA AAGACCCCAA GTACTGGCGA GACCAAGCGC AAGAGACACT GAAATATGCC
CTGGAGCTTC AGAAGCTCAA CACCAACGTG GCTAAGAATG TCATCATGTT CCTGGGAGAT
GGGATGGGTG TCTCCACAGT GACGGCTGCC CGCATCCTCA AGGGTCAGCT CCACCACAAC
CCTGGGGAGG AGACCAGGCT GGAGATGGAC AAGTTCCCCT TCGTGGCCCT CTCCAAGACG
TACAACACCA ATGCCCAGGT CCCTGACAGT GCCGGCACCG CCACCGCCTA CCTGTGTGGG
GTGAAGGCCA ATGAGGGCAC CGTGGGGGTA AGCGCAGCCA CTGAGCGTTC CCGGTGCAAC
ACCACCCAGG GGAACGAGGT CACCTCCATC CTGCGCTGGG CCAAGGACGC TGGGAAATCT
GTGGGCATTG TGACCACCAC GAGAGTGAAC CATGCCACCC CCAGCGCCGC CTACGCCCAC
TCGGCTGACC GGGACTGGTA CTCAGACAAC GAGATGCCCC CTGAGGCCTT GAGCCAGGGC
TGTAAGGACA TCGCCTACCA GCTCATGCAT AACATCAGGG ACATTGACGT GATCATGGGG
GGTGGCCGGA AATACATGTA CCCCAAGAAT AAAACTGATG TGGAGTATGA GAGTGACGAG
AAAGCCAGGG GCACGAGGCT GGACGGCCTG GACCTCGTTG ACACCTGGAA GAGCTTCAAA
CCGAGATACA AGCACTCCCA CTTCATCTGG AACCGCACGG AACTCCTGAC CCTTGACCCC
CACAATGTGG ACTACCTATT GGGTCTCTTC GAGCCAGGGG ACATGCAGTA CGAGCTGAAC
AGGAACAACG TGACGGACCC GTCACTCTCC GAGATGGTGG TGGTGGCCAT CCAGATCCTG
CGGAAGAACC CCAAAGGCTT CTTCTTGCTG GTGGAAGGAG GCAGAATTGA CCACGGGCAC
CATGAAGGAA AAGCCAAGCA GGCCCTGCAT GAGGCGGTGG AGATGGACCG GGCCATCGGG
CAGGCAGGCA GCTTGACCTC CTCGGAAGAC ACTCTGACCG TGGTCACTGC GGACCATTCC
CACGTCTTCA CATTTGGTGG ATACACCCCC CGTGGCAACT CTATCTTTGG TCTGGCCCCC
ATGCTGAGTG ACACAGACAA GAAGCCCTTC ACTGCCATCC TGTATGGCAA TGGGCCTGGC
TACAAGGTGG TGGGCGGTGA ACGAGAGAAT GTCTCCATGG TGGACTATGC TCACAACAAC
TACCAGGCGC AGTCTGCTGT GCCCCTGCGC CACGAGACCC ACGGCGGGGA GGACGTGGCC
GTCTTCTCCA AGGGCCCCAT GGCGCACCTG CTGCACGGCG TCCACGAGCA GAACTACGTC
CCCCACGTGA TGGCGTATGC AGCCTGCATC GGGGCCAACC TCGGCCACTG TGCTCCTGCC
AGCTCGGCAG GCAGCCTTGC TGCAGGCCCC CTGCTGCTCG CGCTGGCCCT CTACCCCCTG
AGCGTCCTGT TCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqXP_005245875.1
CDS235..1809
Misc Feature(1)370..1704(+)
Misc Feature(2)370..1680(+)
Misc Feature(3)412..1596(+)
Translation
Position Chain Variation Link
48 48 a, g dbSNP:763315148
116 116 g, t dbSNP:77354647
124 124 c, g dbSNP:770236595
154 154 a, g dbSNP:528218843
182 182 a, c dbSNP:540299799
184 184 c, t dbSNP:753110554
185 185 a, g dbSNP:756589854
187 187 c, t dbSNP:201284200
188 188 a, g dbSNP:749996516
192 192 a, g, t dbSNP:371685734
204 204 g, t dbSNP:746531325
209 209 a, g dbSNP:754895943
220 220 g, t dbSNP:781172426
221 221 c, t dbSNP:747906165
227 227 a, g dbSNP:769524226
233 233 a, c dbSNP:773092184
238 238 a, g dbSNP:776442538
243 243 a, t dbSNP:749406361
246 246 a, g dbSNP:771198723
256 256 c, t dbSNP:774559268
259 259 g, t dbSNP:759760207
260 260 c, t dbSNP:772679576
274 274 c, t dbSNP:139214514
278 278 c, g dbSNP:150849772
307 307 a, g dbSNP:766948855
312 312 c, t dbSNP:375342528
314 314 a, g dbSNP:146412299
318 318 c, t dbSNP:144632001
323 323 a, g dbSNP:753550135
325 325 a, g dbSNP:757127456
332 332 c, g, t dbSNP:121918005
333 333 a, g dbSNP:772424729
335 335 a, g dbSNP:780221572
340 340 a, g dbSNP:747167000
341 341 c, t dbSNP:199952414
344 344 c, t dbSNP:143358506
345 345 a, g dbSNP:769035516
350 350 a, g dbSNP:777235122
351 351 c, t dbSNP:748438719
353 353 c, t dbSNP:770093969
361 361 c, t dbSNP:148357203
362 362 -, t dbSNP:763244290
381 381 a, c, t dbSNP:539884496
382 382 a, g dbSNP:767216554
393 393 a, t dbSNP:774859071
395 395 -, tca dbSNP:766831104
400 400 a, g dbSNP:760272172
404 404 a, t dbSNP:763919659
405 405 c, t dbSNP:753763521
408 408 a, g dbSNP:757176737
438 438 a, g dbSNP:537814225
442 442 a, g dbSNP:147116628
445 445 a, c, t dbSNP:121918001
446 446 c, g dbSNP:121918003
449 449 c, t dbSNP:781264043
455 455 a, g dbSNP:143885304
474 474 a, c dbSNP:756611513
493 493 c, t dbSNP:778292875
498 498 a, g dbSNP:749630641
501 501 a, g dbSNP:771240396
504 504 c, g dbSNP:779180929
516 516 c, t dbSNP:746608270
517 517 a, g dbSNP:139811782
534 534 a, g dbSNP:191778470
537 537 a, c dbSNP:746273959
541 541 a, g dbSNP:202075854
548 548 c, t dbSNP:768348242
557 557 c, t dbSNP:121918015
564 564 -, tgccggcac dbSNP:200166222
564 564 c, t dbSNP:1780316
565 565 a, g dbSNP:773257111
567 567 c, t dbSNP:769379537
573 573 c, t dbSNP:377453516
575 575 c, t dbSNP:762915678
579 579 c, t dbSNP:770785345
580 580 a, g dbSNP:121918013
590 590 c, g dbSNP:774193109
592 592 -, gg dbSNP:751994699
603 603 a, c dbSNP:201342272
605 605 a, g dbSNP:11586344
609 609 a, g dbSNP:752868525
614 614 a, c dbSNP:146517700
615 615 c, t dbSNP:368714904
618 618 c, g dbSNP:764097939
622 622 a, g dbSNP:753929700
628 628 a, g dbSNP:757771793
632 632 c, g dbSNP:184095519
633 633 c, t dbSNP:750766317
634 634 ac, ca dbSNP:786204530
634 634 a, c dbSNP:758734017
635 635 a, c dbSNP:780583917
640 640 a, c, t dbSNP:747762186
641 641 a, g dbSNP:121918011
646 646 c, t dbSNP:748874853
647 647 a, g dbSNP:140167865
654 654 c, t dbSNP:148982201
659 659 -, c dbSNP:760134827
659 659 c, t dbSNP:745841670
660 660 c, t dbSNP:771727704
666 666 a, g dbSNP:775273192
670 670 a, g dbSNP:138587317
687 687 a, g dbSNP:377693871
688 688 c, t dbSNP:200621180
689 689 a, g dbSNP:149344982
690 690 c, t dbSNP:527613008
693 693 a, g dbSNP:761836226
702 702 c, t dbSNP:143621566
703 703 a, g dbSNP:750842585
718 718 a, g dbSNP:760029254
719 719 g, t dbSNP:121918012
726 726 a, g dbSNP:750079676
728 728 c, t dbSNP:753392973
744 744 c, t dbSNP:373912990
746 746 a, g dbSNP:778232217
752 752 -, c dbSNP:750174638
759 759 c, t dbSNP:766504809
760 760 a, g dbSNP:121918019
762 762 c, t dbSNP:758330265
763 763 a, g dbSNP:199669988
765 765 c, g dbSNP:746782435
768 768 c, g, t dbSNP:201250289
769 769 a, g dbSNP:121918000
770 770 c, t dbSNP:748250829
774 774 c, t dbSNP:770068340
776 776 c, t dbSNP:199590449
784 784 c, t dbSNP:763159520
795 795 c, t dbSNP:771542770
798 798 a, t dbSNP:774949653
804 804 c, g, t dbSNP:760153868
805 805 a, g dbSNP:121918007
808 808 a, g dbSNP:761361696
809 809 c, t dbSNP:765011829
811 811 -, c dbSNP:758124823
816 816 c, t dbSNP:112063292
840 840 a, g dbSNP:200597048
844 844 a, t dbSNP:374558572
846 846 c, t dbSNP:141448778
847 847 a, g dbSNP:751455369
849 849 c, t dbSNP:754911877
851 851 a, c dbSNP:780790767
854 854 a, c dbSNP:121918004
863 863 a, g dbSNP:748031071
877 877 a, g dbSNP:769903299
882 882 c, t dbSNP:201739155
883 883 -, c dbSNP:781213038
884 884 -, aa dbSNP:748254075
884 884 c, t dbSNP:777699004
887 887 a, t dbSNP:746014071
889 889 a, g dbSNP:772432010
891 891 -, g dbSNP:769948289
891 891 g, t dbSNP:776117933
892 892 a, g dbSNP:747488546
895 895 c, g dbSNP:769020799
896 896 c, g, t dbSNP:566317085
901 901 c, t dbSNP:766076920
902 902 a, g dbSNP:199665722
907 907 c, t dbSNP:759125473
910 910 a, c dbSNP:767334437
911 911 c, t dbSNP:752641050
918 918 c, t dbSNP:369550359
921 921 g, t dbSNP:763892146
925 925 a, g dbSNP:746933644
926 926 a, g dbSNP:757551727
935 935 c, t dbSNP:779322468
936 936 g, t dbSNP:745924139
940 940 c, t dbSNP:758451024
941 941 a, g dbSNP:533959092
951 951 c, t dbSNP:780024242
961 961 a, c dbSNP:747480886
968 968 c, t dbSNP:142608957
969 969 a, g dbSNP:776965688
978 978 c, t dbSNP:188689330
979 979 a, g dbSNP:770539523
980 980 c, g, t dbSNP:121918018
985 985 a, g dbSNP:781403334
991 991 a, c, g dbSNP:151270365
992 992 a, t dbSNP:774877541
1002 1002 a, g dbSNP:760649979
1007 1007 a, g dbSNP:764197078
1008 1008 c, t dbSNP:753656794
1015 1015 a, c dbSNP:761753019
1016 1016 a, c, t dbSNP:765149569
1017 1017 a, g dbSNP:537483743
1021 1021 c, t dbSNP:3200254
1025 1025 a, g dbSNP:786204442
1036 1036 c, t dbSNP:751625937
1043 1043 a, g dbSNP:786204634
1048 1048 c, t dbSNP:121918020
1049 1049 a, g, t dbSNP:781272386
1052 1052 c, t dbSNP:148405563
1053 1053 a, g dbSNP:372247799
1055 1055 -, a dbSNP:771175614
1057 1057 c, g dbSNP:749684443
1072 1072 a, c dbSNP:771727865
1080 1080 c, t dbSNP:779625059
1084 1084 c, g dbSNP:746700357
1092 1092 a, g dbSNP:375027534
1093 1093 c, t dbSNP:141742288
1098 1098 c, t dbSNP:754262699
1104 1104 c, t dbSNP:779115195
1105 1105 a, g dbSNP:786204473
1108 1108 a, c, t dbSNP:765458125
1110 1110 a, g dbSNP:3200255
1115 1115 a, c dbSNP:121918002
1121 1121 a, t dbSNP:747637927
1125 1125 a, c dbSNP:755529290
1126 1126 a, g dbSNP:121918017
1136 1136 -, g dbSNP:768160006
1137 1137 a, g dbSNP:749112407
1140 1140 a, c, g dbSNP:560308330
1144 1144 a, g dbSNP:745704006
1148 1148 c, t dbSNP:146908399
1149 1149 a, g dbSNP:527465409
1152 1152 c, t dbSNP:373257447
1154 1154 c, t dbSNP:768555495
1157 1157 a, c, t dbSNP:376221105
1161 1161 c, t dbSNP:762210096
1162 1162 a, t dbSNP:765836269
1164 1164 c, t dbSNP:750783677
1165 1165 a, g dbSNP:763457259
1169 1169 -, tgg dbSNP:756329108
1171 1171 c, g dbSNP:552250079
1186 1186 a, c dbSNP:752356218
1192 1192 c, g dbSNP:755795919
1195 1195 c, t dbSNP:200133602
1196 1196 a, g dbSNP:138679161
1197 1197 a, g dbSNP:757111696
1200 1200 a, g dbSNP:778873231
1211 1211 g, t dbSNP:745830614
1212 1212 -, ctt dbSNP:753338851
1213 1213 c, t dbSNP:121918010
1214 1214 g, t dbSNP:779832611
1224 1224 a, g dbSNP:747146797
1228 1228 a, g dbSNP:768976020
1234 1234 a, g dbSNP:769955594
1235 1235 a, g dbSNP:121918009
1236 1236 c, t dbSNP:370122334
1248 1248 -, g dbSNP:764908423
1248 1248 c, t dbSNP:147688908
1253 1253 a, t dbSNP:763800165
1281 1281 g, t dbSNP:771632536
1290 1290 a, g, t dbSNP:774824768
1302 1302 c, g dbSNP:767794155
1303 1303 c, t dbSNP:776304194
1304 1304 a, g dbSNP:202022405
1311 1311 c, t dbSNP:567349821
1312 1312 a, g dbSNP:749989499
1335 1335 c, t dbSNP:758332051
1337 1337 c, t dbSNP:368809478
1346 1346 c, t dbSNP:751292739
1350 1350 c, g dbSNP:200153944
1353 1353 c, t dbSNP:112335417
1354 1354 a, g dbSNP:552831415
1356 1356 a, g dbSNP:748337342
1364 1364 c, t dbSNP:756418235
1365 1365 a, g dbSNP:777986840
1367 1367 a, t dbSNP:121918008
1373 1373 -, c dbSNP:758119185
1377 1377 c, t dbSNP:749419329
1378 1378 a, g dbSNP:771540767
1393 1393 a, g dbSNP:150594290
1399 1399 -, c dbSNP:751404811
1399 1399 a, g dbSNP:774870859
1400 1400 a, c dbSNP:746390776
1400 1400 -, c dbSNP:779683021
1401 1401 c, t dbSNP:772412576
1405 1405 c, t dbSNP:371243939
1410 1410 c, g dbSNP:375767924
1415 1415 -, t dbSNP:754826836
1416 1416 c, t dbSNP:764940488
1417 1417 a, g dbSNP:772682471
1418 1418 c, t dbSNP:751977466
1431 1431 c, t dbSNP:764010876
1435 1435 a, c dbSNP:754044587
1442 1442 a, c, g dbSNP:757564264
1461 1461 c, t dbSNP:750530891
1467 1467 c, t dbSNP:758911741
1468 1468 g, t dbSNP:780478066
1479 1479 c, t dbSNP:747539132
1484 1484 a, g dbSNP:121918014
1497 1497 c, t dbSNP:780762265
1508 1508 a, g dbSNP:781543452
1509 1509 c, t dbSNP:748883680
1510 1510 a, g dbSNP:770548228
1514 1514 a, c dbSNP:773907984
1516 1516 c, t dbSNP:759017288
1524 1524 c, t dbSNP:200330153
1537 1537 c, g dbSNP:771633915
1540 1540 c, t dbSNP:121918006
1542 1542 c, t dbSNP:775526490
1547 1547 -, aca dbSNP:771212957
1548 1548 c, t dbSNP:757045880
1550 1550 a, g dbSNP:368408859
1562 1562 a, c, g dbSNP:768053120
1563 1563 a, g dbSNP:756394364
1582 1582 c, t dbSNP:138690664
1583 1583 a, g dbSNP:150799088
1585 1585 c, t dbSNP:758125155
1587 1587 c, t dbSNP:377110098
1592 1592 -, c dbSNP:774529894
1596 1596 c, t dbSNP:746554462
1597 1597 a, g dbSNP:149889416
1599 1599 c, t dbSNP:370212283
1600 1600 a, g dbSNP:121918016
1600 1600 -, g dbSNP:746256993
1608 1608 c, t dbSNP:776664499
1614 1614 c, t dbSNP:371984578
1615 1615 a, g dbSNP:34810399
1631 1631 c, g dbSNP:773075737
1634 1634 c, t dbSNP:763073466
1637 1637 c, t dbSNP:766656419
1638 1638 a, g dbSNP:774384124
1640 1640 a, g dbSNP:759662331
1642 1642 c, t dbSNP:767614891
1650 1650 c, t dbSNP:369433931
1653 1653 a, c, t dbSNP:373417343
1654 1654 a, g dbSNP:376354718
1656 1656 c, t dbSNP:12027316
1659 1659 c, t dbSNP:183381346
1671 1671 c, t dbSNP:527657489
1674 1674 c, t dbSNP:540139632
1675 1675 c, t dbSNP:754502257
1678 1678 a, c dbSNP:780857373
1680 1680 c, t dbSNP:747980975
1682 1682 c, t dbSNP:769829312
1689 1689 a, g dbSNP:188443578
1698 1698 c, t dbSNP:749148162
1704 1704 c, t dbSNP:771120248
1710 1710 c, t dbSNP:774516408
1713 1713 c, t dbSNP:759758484
1714 1714 c, t dbSNP:772080508
1716 1716 c, t dbSNP:142545037
1717 1717 a, c, g dbSNP:761079751
1726 1726 a, g dbSNP:754125867
1732 1732 a, g dbSNP:762216748
1739 1739 c, t dbSNP:550358395
1740 1740 a, g dbSNP:751195005
1749 1749 a, c dbSNP:754694335
1760 1760 a, g, t dbSNP:79250591
1762 1762 c, t dbSNP:752320340
1765 1765 c, t dbSNP:755976886
1773 1773 c, t dbSNP:529786148
1774 1774 a, g dbSNP:367657406
1775 1775 c, t dbSNP:371373128
1776 1776 a, g, t dbSNP:3200256
1780 1780 a, g dbSNP:772346350
1789 1789 c, g, t dbSNP:775398905
1791 1791 a, c, g, t dbSNP:376020180
1793 1793 -, t dbSNP:387906525
1794 1794 a, g dbSNP:765641649
1796 1796 a, g dbSNP:368326384
1797 1797 c, g dbSNP:370978556
1798 1798 a, g dbSNP:372315234
1799 1799 c, t dbSNP:34605986
1808 1808 -, g dbSNP:764994176
1812 1812 g, t dbSNP:755602034
1814 1814 c, g dbSNP:763515495
1816 1816 a, g dbSNP:753716865
1820 1820 c, t dbSNP:757240883
1821 1821 c, t dbSNP:778673244
1822 1822 c, t dbSNP:559330654
1823 1823 a, g dbSNP:571140206
1826 1826 c, t dbSNP:780269910
1829 1829 c, t dbSNP:567336093
1834 1834 a, t dbSNP:747222706
1835 1835 a, g dbSNP:375281601
1838 1838 c, t dbSNP:768718338
1850 1850 c, t dbSNP:776868579
1852 1852 a, g dbSNP:748654072
1860 1860 a, c dbSNP:770493812
1869 1869 c, g dbSNP:367637559
1873 1873 a, c, g dbSNP:565251838
1874 1874 a, c, t dbSNP:1697405
1875 1875 a, c dbSNP:78043671
1875 1875 -, c dbSNP:371832452
1931 1931 -, c dbSNP:140511985
1932 1932 c, t dbSNP:553947949
1935 1935 a, g dbSNP:1697406
1951 1951 c, t dbSNP:545776624
1952 1952 g, t dbSNP:766588843
1958 1958 c, t dbSNP:564863879
1960 1960 c, t dbSNP:532269853
1987 1987 a, g dbSNP:776773091
2013 2013 c, t dbSNP:116162120
2026 2026 c, t dbSNP:373909118
2027 2027 a, g dbSNP:529801718
2042 2042 a, c dbSNP:1772719
2067 2067 c, t dbSNP:765353111
2070 2070 a, c dbSNP:751503180
2071 2071 c, g dbSNP:566407347
2081 2081 g, t dbSNP:527314874
2085 2085 g, t dbSNP:552201420
2096 2096 a, g dbSNP:757243859
2114 2114 c, t dbSNP:76073898
2129 2129 a, g dbSNP:750252193
2146 2146 a, g dbSNP:538549134
2171 2171 a, g dbSNP:556534930
2197 2197 c, t dbSNP:2242420
2210 2210 -, ctc dbSNP:531742327
2242 2242 a, g dbSNP:2242421
2269 2269 a, g dbSNP:114552089
2282 2282 g, t dbSNP:536009840
2289 2289 a, c dbSNP:138564953
2357 2357 c, t dbSNP:754489263
2384 2384 c, t dbSNP:141554698
2397 2397 a, g dbSNP:778461715
2403 2403 a, g dbSNP:747561664
2446 2446 a, g dbSNP:111947234
2472 2472 c, g dbSNP:145193027
2489 2489 a, g dbSNP:562609652
2494 2494 -, t dbSNP:200291738
2494 2494 a, t dbSNP:78801483
2501 2501 c, t dbSNP:541640914
2506 2506 c, t dbSNP:41265991
2511 2511 -, tgg dbSNP:769940109
2558 2558 a, c dbSNP:139022638

Target ORF information:

RefSeq Version XM_005245818
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens alkaline phosphatase, liver/bone/kidney (ALPL), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_005245818

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
ATGATTTCAC CATTCTTAGT ACTGGCCATT GGCACCTGCC TTACTAACTC CTTAGTGCCA 
GAGAAAGAGA AAGACCCCAA GTACTGGCGA GACCAAGCGC AAGAGACACT GAAATATGCC
CTGGAGCTTC AGAAGCTCAA CACCAACGTG GCTAAGAATG TCATCATGTT CCTGGGAGAT
GGGATGGGTG TCTCCACAGT GACGGCTGCC CGCATCCTCA AGGGTCAGCT CCACCACAAC
CCTGGGGAGG AGACCAGGCT GGAGATGGAC AAGTTCCCCT TCGTGGCCCT CTCCAAGACG
TACAACACCA ATGCCCAGGT CCCTGACAGT GCCGGCACCG CCACCGCCTA CCTGTGTGGG
GTGAAGGCCA ATGAGGGCAC CGTGGGGGTA AGCGCAGCCA CTGAGCGTTC CCGGTGCAAC
ACCACCCAGG GGAACGAGGT CACCTCCATC CTGCGCTGGG CCAAGGACGC TGGGAAATCT
GTGGGCATTG TGACCACCAC GAGAGTGAAC CATGCCACCC CCAGCGCCGC CTACGCCCAC
TCGGCTGACC GGGACTGGTA CTCAGACAAC GAGATGCCCC CTGAGGCCTT GAGCCAGGGC
TGTAAGGACA TCGCCTACCA GCTCATGCAT AACATCAGGG ACATTGACGT GATCATGGGG
GGTGGCCGGA AATACATGTA CCCCAAGAAT AAAACTGATG TGGAGTATGA GAGTGACGAG
AAAGCCAGGG GCACGAGGCT GGACGGCCTG GACCTCGTTG ACACCTGGAA GAGCTTCAAA
CCGAGATACA AGCACTCCCA CTTCATCTGG AACCGCACGG AACTCCTGAC CCTTGACCCC
CACAATGTGG ACTACCTATT GGGTCTCTTC GAGCCAGGGG ACATGCAGTA CGAGCTGAAC
AGGAACAACG TGACGGACCC GTCACTCTCC GAGATGGTGG TGGTGGCCAT CCAGATCCTG
CGGAAGAACC CCAAAGGCTT CTTCTTGCTG GTGGAAGGAG GCAGAATTGA CCACGGGCAC
CATGAAGGAA AAGCCAAGCA GGCCCTGCAT GAGGCGGTGG AGATGGACCG GGCCATCGGG
CAGGCAGGCA GCTTGACCTC CTCGGAAGAC ACTCTGACCG TGGTCACTGC GGACCATTCC
CACGTCTTCA CATTTGGTGG ATACACCCCC CGTGGCAACT CTATCTTTGG TCTGGCCCCC
ATGCTGAGTG ACACAGACAA GAAGCCCTTC ACTGCCATCC TGTATGGCAA TGGGCCTGGC
TACAAGGTGG TGGGCGGTGA ACGAGAGAAT GTCTCCATGG TGGACTATGC TCACAACAAC
TACCAGGCGC AGTCTGCTGT GCCCCTGCGC CACGAGACCC ACGGCGGGGA GGACGTGGCC
GTCTTCTCCA AGGGCCCCAT GGCGCACCTG CTGCACGGCG TCCACGAGCA GAACTACGTC
CCCCACGTGA TGGCGTATGC AGCCTGCATC GGGGCCAACC TCGGCCACTG TGCTCCTGCC
AGCTCGGCAG GCAGCCTTGC TGCAGGCCCC CTGCTGCTCG CGCTGGCCCT CTACCCCCTG
AGCGTCCTGT TCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu33311
Accession Version XM_005245820.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1173bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product alkaline phosphatase, tissue-nonspecific isozyme isoform X2
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_032977.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced gi:530360993. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
ATGATTTCAC CATTCTTAGT ACTGGCCATT GGCACCTGCC TTACTAACTC CTTAGTGCCA 
GAGAAAGAGA AAGACCCCAA GTACTGGCGA GACCAAGCGC AAGAGACACT GAAATATGCC
CTGGAGCTTC AGAAGCTCAA CACCAACGTG GCTAAGAATG TCATCATGTT CCTGGGAGAT
GGGATGGGTG TCTCCACAGT GACGGCTGCC CGCATCCTCA AGGGTCAGCT CCACCACAAC
CCTGGGGAGG AGACCAGGCT GGAGATGGAC AAGTTCCCCT TCGTGGCCCT CTCCAAGACG
TACAACACCA ATGCCCAGGT CCCTGACAGT GCCGGCACCG CCACCGCCTA CCTGTGTGGG
GTGAAGGCCA ATGAGGGCAC CGTGGGGGTA AGCGCAGCCA CTGAGCGTTC CCGGTGCAAC
ACCACCCAGG GGAACGAGGT CACCTCCATC CTGCGCTGGG CCAAGGACGC TGGGAAATCT
GTGGGCATTG TGACCACCAC GAGAGTGAAC CATGCCACCC CCAGCGCCGC CTACGCCCAC
TCGGCTGACC GGGACTGGTA CTCAGACAAC GAGATGCCCC CTGAGGCCTT GAGCCAGGGC
TGTAAGGACA TCGCCTACCA GCTCATGCAT AACATCAGGG ACATTGACGT GATCATGGGG
GGTGGCCGGA AATACATGTA CCCCAAGAAT AAAACTGATG TGGAGTATGA GAGTGACGAG
AAAGCCAGGG GCACGAGGCT GGACGGCCTG GACCTCGTTG ACACCTGGAA GAGCTTCAAA
CCGAGATACA AGCACTCCCA CTTCATCTGG AACCGCACGG AACTCCTGAC CCTTGACCCC
CACAATGTGG ACTACCTATT GGGTCTCTTC GAGCCAGGGG ACATGCAGTA CGAGCTGAAC
AGGAACAACG TGACGGACCC GTCACTCTCC GAGATGGTGG TGGTGGCCAT CCAGATCCTG
CGGAAGAACC CCAAAGGCTT CTTCTTGCTG GTGGAAGGAG GCAGATTTCT CCCCTTTGGT
AGTCTTTCTT GGGGACCTGG CCCTGAAGGG GCAAGCAGCC CCTCAGCCTC ACTGCCCAGA
AAAGCAAATC CGCAGGCCCC GGCTTTCCCA CGCTGTGTGC TGATGTTCCC AGGCTCTTTC
AGCGCCGGCC AGGGGCCTTG CAGACAGACC TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqXP_005245877.1
CDS197..1369
Misc Feature(1)332..>1201(+)
Misc Feature(2)332..637(+)
Misc Feature(3)374..1192(+)
Translation
Position Chain Variation Link
3 3 c, g dbSNP:111601456
13 13 c, t dbSNP:371922238
116 116 a, g dbSNP:528218843
144 144 a, c dbSNP:540299799
146 146 c, t dbSNP:753110554
147 147 a, g dbSNP:756589854
149 149 c, t dbSNP:201284200
150 150 a, g dbSNP:749996516
154 154 a, g, t dbSNP:371685734
166 166 g, t dbSNP:746531325
171 171 a, g dbSNP:754895943
182 182 g, t dbSNP:781172426
183 183 c, t dbSNP:747906165
189 189 a, g dbSNP:769524226
195 195 a, c dbSNP:773092184
200 200 a, g dbSNP:776442538
205 205 a, t dbSNP:749406361
208 208 a, g dbSNP:771198723
218 218 c, t dbSNP:774559268
221 221 g, t dbSNP:759760207
222 222 c, t dbSNP:772679576
236 236 c, t dbSNP:139214514
240 240 c, g dbSNP:150849772
269 269 a, g dbSNP:766948855
274 274 c, t dbSNP:375342528
276 276 a, g dbSNP:146412299
280 280 c, t dbSNP:144632001
285 285 a, g dbSNP:753550135
287 287 a, g dbSNP:757127456
294 294 c, g, t dbSNP:121918005
295 295 a, g dbSNP:772424729
297 297 a, g dbSNP:780221572
302 302 a, g dbSNP:747167000
303 303 c, t dbSNP:199952414
306 306 c, t dbSNP:143358506
307 307 a, g dbSNP:769035516
312 312 a, g dbSNP:777235122
313 313 c, t dbSNP:748438719
315 315 c, t dbSNP:770093969
323 323 c, t dbSNP:148357203
324 324 -, t dbSNP:763244290
343 343 a, c, t dbSNP:539884496
344 344 a, g dbSNP:767216554
355 355 a, t dbSNP:774859071
357 357 -, tca dbSNP:766831104
362 362 a, g dbSNP:760272172
366 366 a, t dbSNP:763919659
367 367 c, t dbSNP:753763521
370 370 a, g dbSNP:757176737
400 400 a, g dbSNP:537814225
404 404 a, g dbSNP:147116628
407 407 a, c, t dbSNP:121918001
408 408 c, g dbSNP:121918003
411 411 c, t dbSNP:781264043
417 417 a, g dbSNP:143885304
436 436 a, c dbSNP:756611513
455 455 c, t dbSNP:778292875
460 460 a, g dbSNP:749630641
463 463 a, g dbSNP:771240396
466 466 c, g dbSNP:779180929
478 478 c, t dbSNP:746608270
479 479 a, g dbSNP:139811782
496 496 a, g dbSNP:191778470
499 499 a, c dbSNP:746273959
503 503 a, g dbSNP:202075854
510 510 c, t dbSNP:768348242
519 519 c, t dbSNP:121918015
526 526 -, tgccggcac dbSNP:200166222
526 526 c, t dbSNP:1780316
527 527 a, g dbSNP:773257111
529 529 c, t dbSNP:769379537
535 535 c, t dbSNP:377453516
537 537 c, t dbSNP:762915678
541 541 c, t dbSNP:770785345
542 542 a, g dbSNP:121918013
552 552 c, g dbSNP:774193109
554 554 -, gg dbSNP:751994699
565 565 a, c dbSNP:201342272
567 567 a, g dbSNP:11586344
571 571 a, g dbSNP:752868525
576 576 a, c dbSNP:146517700
577 577 c, t dbSNP:368714904
580 580 c, g dbSNP:764097939
584 584 a, g dbSNP:753929700
590 590 a, g dbSNP:757771793
594 594 c, g dbSNP:184095519
595 595 c, t dbSNP:750766317
596 596 ac, ca dbSNP:786204530
596 596 a, c dbSNP:758734017
597 597 a, c dbSNP:780583917
602 602 a, c, t dbSNP:747762186
603 603 a, g dbSNP:121918011
608 608 c, t dbSNP:748874853
609 609 a, g dbSNP:140167865
616 616 c, t dbSNP:148982201
621 621 -, c dbSNP:760134827
621 621 c, t dbSNP:745841670
622 622 c, t dbSNP:771727704
628 628 a, g dbSNP:775273192
632 632 a, g dbSNP:138587317
649 649 a, g dbSNP:377693871
650 650 c, t dbSNP:200621180
651 651 a, g dbSNP:149344982
652 652 c, t dbSNP:527613008
655 655 a, g dbSNP:761836226
664 664 c, t dbSNP:143621566
665 665 a, g dbSNP:750842585
680 680 a, g dbSNP:760029254
681 681 g, t dbSNP:121918012
688 688 a, g dbSNP:750079676
690 690 c, t dbSNP:753392973
706 706 c, t dbSNP:373912990
708 708 a, g dbSNP:778232217
714 714 -, c dbSNP:750174638
721 721 c, t dbSNP:766504809
722 722 a, g dbSNP:121918019
724 724 c, t dbSNP:758330265
725 725 a, g dbSNP:199669988
727 727 c, g dbSNP:746782435
730 730 c, g, t dbSNP:201250289
731 731 a, g dbSNP:121918000
732 732 c, t dbSNP:748250829
736 736 c, t dbSNP:770068340
738 738 c, t dbSNP:199590449
746 746 c, t dbSNP:763159520
757 757 c, t dbSNP:771542770
760 760 a, t dbSNP:774949653
766 766 c, g, t dbSNP:760153868
767 767 a, g dbSNP:121918007
770 770 a, g dbSNP:761361696
771 771 c, t dbSNP:765011829
773 773 -, c dbSNP:758124823
778 778 c, t dbSNP:112063292
802 802 a, g dbSNP:200597048
806 806 a, t dbSNP:374558572
808 808 c, t dbSNP:141448778
809 809 a, g dbSNP:751455369
811 811 c, t dbSNP:754911877
813 813 a, c dbSNP:780790767
816 816 a, c dbSNP:121918004
825 825 a, g dbSNP:748031071
839 839 a, g dbSNP:769903299
844 844 c, t dbSNP:201739155
845 845 -, c dbSNP:781213038
846 846 -, aa dbSNP:748254075
846 846 c, t dbSNP:777699004
849 849 a, t dbSNP:746014071
851 851 a, g dbSNP:772432010
853 853 -, g dbSNP:769948289
853 853 g, t dbSNP:776117933
854 854 a, g dbSNP:747488546
857 857 c, g dbSNP:769020799
858 858 c, g, t dbSNP:566317085
863 863 c, t dbSNP:766076920
864 864 a, g dbSNP:199665722
869 869 c, t dbSNP:759125473
872 872 a, c dbSNP:767334437
873 873 c, t dbSNP:752641050
880 880 c, t dbSNP:369550359
883 883 g, t dbSNP:763892146
887 887 a, g dbSNP:746933644
888 888 a, g dbSNP:757551727
897 897 c, t dbSNP:779322468
898 898 g, t dbSNP:745924139
902 902 c, t dbSNP:758451024
903 903 a, g dbSNP:533959092
913 913 c, t dbSNP:780024242
923 923 a, c dbSNP:747480886
930 930 c, t dbSNP:142608957
931 931 a, g dbSNP:776965688
940 940 c, t dbSNP:188689330
941 941 a, g dbSNP:770539523
942 942 c, g, t dbSNP:121918018
947 947 a, g dbSNP:781403334
953 953 a, c, g dbSNP:151270365
954 954 a, t dbSNP:774877541
964 964 a, g dbSNP:760649979
969 969 a, g dbSNP:764197078
970 970 c, t dbSNP:753656794
977 977 a, c dbSNP:761753019
978 978 a, c, t dbSNP:765149569
979 979 a, g dbSNP:537483743
983 983 c, t dbSNP:3200254
987 987 a, g dbSNP:786204442
998 998 c, t dbSNP:751625937
1005 1005 a, g dbSNP:786204634
1010 1010 c, t dbSNP:121918020
1011 1011 a, g, t dbSNP:781272386
1014 1014 c, t dbSNP:148405563
1015 1015 a, g dbSNP:372247799
1017 1017 -, a dbSNP:771175614
1019 1019 c, g dbSNP:749684443
1034 1034 a, c dbSNP:771727865
1042 1042 c, t dbSNP:779625059
1046 1046 c, g dbSNP:746700357
1054 1054 a, g dbSNP:375027534
1055 1055 c, t dbSNP:141742288
1060 1060 c, t dbSNP:754262699
1066 1066 c, t dbSNP:779115195
1067 1067 a, g dbSNP:786204473
1070 1070 a, c, t dbSNP:765458125
1072 1072 a, g dbSNP:3200255
1077 1077 a, c dbSNP:121918002
1083 1083 a, t dbSNP:747637927
1087 1087 a, c dbSNP:755529290
1088 1088 a, g dbSNP:121918017
1098 1098 -, g dbSNP:768160006
1099 1099 a, g dbSNP:749112407
1102 1102 a, c, g dbSNP:560308330
1106 1106 a, g dbSNP:745704006
1110 1110 c, t dbSNP:146908399
1111 1111 a, g dbSNP:527465409
1114 1114 c, t dbSNP:373257447
1116 1116 c, t dbSNP:768555495
1119 1119 a, c, t dbSNP:376221105
1123 1123 c, t dbSNP:762210096
1124 1124 a, t dbSNP:765836269
1126 1126 c, t dbSNP:750783677
1127 1127 a, g dbSNP:763457259
1131 1131 -, tgg dbSNP:756329108
1133 1133 c, g dbSNP:552250079
1148 1148 a, c dbSNP:752356218
1154 1154 c, g dbSNP:755795919
1157 1157 c, t dbSNP:200133602
1158 1158 a, g dbSNP:138679161
1159 1159 a, g dbSNP:757111696
1162 1162 a, g dbSNP:778873231
1173 1173 g, t dbSNP:745830614
1174 1174 -, ctt dbSNP:753338851
1175 1175 c, t dbSNP:121918010
1176 1176 g, t dbSNP:779832611
1186 1186 a, g dbSNP:747146797
1190 1190 a, g dbSNP:768976020
1197 1197 a, g dbSNP:542668971
1242 1242 a, g dbSNP:2275368
1244 1244 -, g dbSNP:34470994
1248 1248 c, t dbSNP:2275367
1255 1255 c, g dbSNP:546009801
1285 1285 a, c, t dbSNP:377724919
1286 1286 c, t dbSNP:191761285
1287 1287 c, t dbSNP:531412806
1292 1292 a, g dbSNP:549836823
1310 1310 c, t dbSNP:568078803
1312 1312 c, t dbSNP:116907127
1321 1321 a, g dbSNP:754493473
1331 1331 -, tctt dbSNP:567937988
1342 1342 c, t dbSNP:548073058
1343 1343 a, g dbSNP:373559812
1384 1384 a, g dbSNP:765800129
1399 1399 c, t dbSNP:536503306
1400 1400 a, c, g dbSNP:754409126
1408 1408 c, t dbSNP:765721915
1410 1410 c, t dbSNP:551559395
1416 1416 a, g dbSNP:569845980
1477 1477 a, g dbSNP:753141034
1516 1516 a, g dbSNP:758765676
1538 1538 a, t dbSNP:537161542
1550 1550 a, g dbSNP:1767447
1575 1575 a, g dbSNP:573980103
1626 1626 g, t dbSNP:534667896
1639 1639 g, t dbSNP:752462587
1640 1640 a, g dbSNP:758109839
1662 1662 a, g dbSNP:554074393
1663 1663 c, t dbSNP:112953683
1675 1675 c, t dbSNP:571677374
1676 1676 a, g dbSNP:572246306
1684 1684 -, ac dbSNP:3835555
1685 1685 -, ac, ca dbSNP:61408611
1692 1692 -, ca dbSNP:377252377
1693 1693 -, ca dbSNP:397791862
1708 1708 c, t dbSNP:781113693
1731 1731 c, t dbSNP:745913282
1732 1732 g, t dbSNP:184984947
1740 1740 a, t dbSNP:564257749
1757 1757 a, g dbSNP:576270197
1773 1773 c, t dbSNP:371619119
1774 1774 a, g dbSNP:146157827
1776 1776 a, c dbSNP:202099119
1777 1777 c, t dbSNP:187911240
1792 1792 a, g dbSNP:768507468
1795 1795 a, g dbSNP:557412579
1813 1813 a, c, g dbSNP:28497583
1834 1834 c, t dbSNP:140167579
1849 1849 c, t dbSNP:533426916
1851 1851 c, t dbSNP:141524959
1858 1858 g, t dbSNP:569934693
1866 1866 c, t dbSNP:577366285
1867 1867 a, g dbSNP:771839503

Target ORF information:

RefSeq Version XM_005245820
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens alkaline phosphatase, liver/bone/kidney (ALPL), transcript variant X3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_005245820

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
ATGATTTCAC CATTCTTAGT ACTGGCCATT GGCACCTGCC TTACTAACTC CTTAGTGCCA 
GAGAAAGAGA AAGACCCCAA GTACTGGCGA GACCAAGCGC AAGAGACACT GAAATATGCC
CTGGAGCTTC AGAAGCTCAA CACCAACGTG GCTAAGAATG TCATCATGTT CCTGGGAGAT
GGGATGGGTG TCTCCACAGT GACGGCTGCC CGCATCCTCA AGGGTCAGCT CCACCACAAC
CCTGGGGAGG AGACCAGGCT GGAGATGGAC AAGTTCCCCT TCGTGGCCCT CTCCAAGACG
TACAACACCA ATGCCCAGGT CCCTGACAGT GCCGGCACCG CCACCGCCTA CCTGTGTGGG
GTGAAGGCCA ATGAGGGCAC CGTGGGGGTA AGCGCAGCCA CTGAGCGTTC CCGGTGCAAC
ACCACCCAGG GGAACGAGGT CACCTCCATC CTGCGCTGGG CCAAGGACGC TGGGAAATCT
GTGGGCATTG TGACCACCAC GAGAGTGAAC CATGCCACCC CCAGCGCCGC CTACGCCCAC
TCGGCTGACC GGGACTGGTA CTCAGACAAC GAGATGCCCC CTGAGGCCTT GAGCCAGGGC
TGTAAGGACA TCGCCTACCA GCTCATGCAT AACATCAGGG ACATTGACGT GATCATGGGG
GGTGGCCGGA AATACATGTA CCCCAAGAAT AAAACTGATG TGGAGTATGA GAGTGACGAG
AAAGCCAGGG GCACGAGGCT GGACGGCCTG GACCTCGTTG ACACCTGGAA GAGCTTCAAA
CCGAGATACA AGCACTCCCA CTTCATCTGG AACCGCACGG AACTCCTGAC CCTTGACCCC
CACAATGTGG ACTACCTATT GGGTCTCTTC GAGCCAGGGG ACATGCAGTA CGAGCTGAAC
AGGAACAACG TGACGGACCC GTCACTCTCC GAGATGGTGG TGGTGGCCAT CCAGATCCTG
CGGAAGAACC CCAAAGGCTT CTTCTTGCTG GTGGAAGGAG GCAGATTTCT CCCCTTTGGT
AGTCTTTCTT GGGGACCTGG CCCTGAAGGG GCAAGCAGCC CCTCAGCCTC ACTGCCCAGA
AAAGCAAATC CGCAGGCCCC GGCTTTCCCA CGCTGTGTGC TGATGTTCCC AGGCTCTTTC
AGCGCCGGCC AGGGGCCTTG CAGACAGACC TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu22555
Accession Version NM_001127501.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1410bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product alkaline phosphatase, tissue-nonspecific isozyme isoform 2
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CN425768.1, DA574668.1, AK298085.1, BC021289.2 and AL359815.26. On Apr 13, 2010 this sequence version replaced gi:188595717. Summary: There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization; however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to hypophosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of this disorder can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms. Alternatively spliced transcript variants have been described. [provided by RefSeq, Apr 2010]. Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream start codon, compared to variant 1. The encoded isoform (2) is shorter than isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK298085.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGTTCCTGG GAGATGGGAT GGGTGTCTCC ACAGTGACGG CTGCCCGCAT CCTCAAGGGT 
CAGCTCCACC ACAACCCTGG GGAGGAGACC AGGCTGGAGA TGGACAAGTT CCCCTTCGTG
GCCCTCTCCA AGACGTACAA CACCAATGCC CAGGTCCCTG ACAGCGCCGG CACCGCCACC
GCCTACCTGT GTGGGGTGAA GGCCAATGAG GGCACCGTGG GGGTAAGCGC AGCCACTGAG
CGTTCCCGGT GCAACACCAC CCAGGGGAAC GAGGTCACCT CCATCCTGCG CTGGGCCAAG
GACGCTGGGA AATCTGTGGG CATTGTGACC ACCACGAGAG TGAACCATGC CACCCCCAGC
GCCGCCTACG CCCACTCGGC TGACCGGGAC TGGTACTCAG ACAACGAGAT GCCCCCTGAG
GCCTTGAGCC AGGGCTGTAA GGACATCGCC TACCAGCTCA TGCATAACAT CAGGGACATT
GACGTGATCA TGGGGGGTGG CCGGAAATAC ATGTACCCCA AGAATAAAAC TGATGTGGAG
TATGAGAGTG ACGAGAAAGC CAGGGGCACG AGGCTGGACG GCCTGGACCT CGTTGACACC
TGGAAGAGCT TCAAACCGAG ATACAAGCAC TCCCACTTCA TCTGGAACCG CACGGAACTC
CTGACCCTTG ACCCCCACAA TGTGGACTAC CTATTGGGTC TCTTCGAGCC AGGGGACATG
CAGTACGAGC TGAACAGGAA CAACGTGACG GACCCGTCAC TCTCCGAGAT GGTGGTGGTG
GCCATCCAGA TCCTGCGGAA GAACCCCAAA GGCTTCTTCT TGCTGGTGGA AGGAGGCAGA
ATTGACCACG GGCACCATGA AGGAAAAGCC AAGCAGGCCC TGCATGAGGC GGTGGAGATG
GACCGGGCCA TCGGGCAGGC AGGCAGCTTG ACCTCCTCGG AAGACACTCT GACCGTGGTC
ACTGCGGACC ATTCCCACGT CTTCACATTT GGTGGATACA CCCCCCGTGG CAACTCTATC
TTTGGTCTGG CCCCCATGCT GAGTGACACA GACAAGAAGC CCTTCACTGC CATCCTGTAT
GGCAATGGGC CTGGCTACAA GGTGGTGGGC GGTGAACGAG AGAATGTCTC CATGGTGGAC
TATGCTCACA ACAACTACCA GGCGCAGTCT GCTGTGCCCC TGCGCCACGA GACCCACGGC
GGGGAGGACG TGGCCGTCTT CTCCAAGGGC CCCATGGCGC ACCTGCTGCA CGGCGTCCAC
GAGCAGAACT ACGTCCCCCA CGTGATGGCG TATGCAGCCT GCATCGGGGC CAACCTCGGC
CACTGTGCTC CTGCCAGCTC GGCAGGCAGC CTTGCTGCAG GCCCCCTGCT GCTCGCGCTG
GCCCTCTACC CCCTGAGCGT CCTGTTCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqNP_001120973.2
CDS258..1667
Misc Feature(1)258..1562(+)
Misc Feature(2)270..1454(+)
Misc Feature(3)282..1538(+)
Exon (1)1..153
Gene:ALPL
Gene Synonym:
Exon (2)154..273
Gene:ALPL
Gene Synonym:
Exon (3)274..389
Gene:ALPL
Gene Synonym:
Exon (4)390..564
Gene:ALPL
Gene Synonym:
Exon (5)565..740
Gene:ALPL
Gene Synonym:
Exon (6)741..884
Gene:ALPL
Gene Synonym:
Exon (7)885..954
Gene:ALPL
Gene Synonym:
Exon (8)955..1089
Gene:ALPL
Gene Synonym:
Exon (9)1090..1281
Gene:ALPL
Gene Synonym:
Exon (10)1282..1401
Gene:ALPL
Gene Synonym:
Exon (11)1402..2431
Gene:ALPL
Gene Synonym:
Translation
Position Chain Variation Link
5 5 a, g dbSNP:554887643
64 64 c, g dbSNP:111601456
74 74 c, t dbSNP:371922238
165 165 a, g dbSNP:766948855
170 170 c, t dbSNP:375342528
172 172 a, g dbSNP:146412299
176 176 c, t dbSNP:144632001
181 181 a, g dbSNP:753550135
183 183 a, g dbSNP:757127456
190 190 c, g, t dbSNP:121918005
191 191 a, g dbSNP:772424729
193 193 a, g dbSNP:780221572
198 198 a, g dbSNP:747167000
199 199 c, t dbSNP:199952414
202 202 c, t dbSNP:143358506
203 203 a, g dbSNP:769035516
208 208 a, g dbSNP:777235122
209 209 c, t dbSNP:748438719
211 211 c, t dbSNP:770093969
219 219 c, t dbSNP:148357203
220 220 -, t dbSNP:763244290
239 239 a, c, t dbSNP:539884496
240 240 a, g dbSNP:767216554
251 251 a, t dbSNP:774859071
253 253 -, tca dbSNP:766831104
258 258 a, g dbSNP:760272172
262 262 a, t dbSNP:763919659
263 263 c, t dbSNP:753763521
266 266 a, g dbSNP:757176737
296 296 a, g dbSNP:537814225
300 300 a, g dbSNP:147116628
303 303 a, c, t dbSNP:121918001
304 304 c, g dbSNP:121918003
307 307 c, t dbSNP:781264043
313 313 a, g dbSNP:143885304
332 332 a, c dbSNP:756611513
351 351 c, t dbSNP:778292875
356 356 a, g dbSNP:749630641
359 359 a, g dbSNP:771240396
362 362 c, g dbSNP:779180929
374 374 c, t dbSNP:746608270
375 375 a, g dbSNP:139811782
392 392 a, g dbSNP:191778470
395 395 a, c dbSNP:746273959
399 399 a, g dbSNP:202075854
406 406 c, t dbSNP:768348242
415 415 c, t dbSNP:121918015
422 422 -, tgccggcac dbSNP:200166222
422 422 c, t dbSNP:1780316
423 423 a, g dbSNP:773257111
425 425 c, t dbSNP:769379537
431 431 c, t dbSNP:377453516
433 433 c, t dbSNP:762915678
437 437 c, t dbSNP:770785345
438 438 a, g dbSNP:121918013
448 448 c, g dbSNP:774193109
450 450 -, gg dbSNP:751994699
461 461 a, c dbSNP:201342272
463 463 a, g dbSNP:11586344
467 467 a, g dbSNP:752868525
472 472 a, c dbSNP:146517700
473 473 c, t dbSNP:368714904
476 476 c, g dbSNP:764097939
480 480 a, g dbSNP:753929700
486 486 a, g dbSNP:757771793
490 490 c, g dbSNP:184095519
491 491 c, t dbSNP:750766317
492 492 ac, ca dbSNP:786204530
492 492 a, c dbSNP:758734017
493 493 a, c dbSNP:780583917
498 498 a, c, t dbSNP:747762186
499 499 a, g dbSNP:121918011
504 504 c, t dbSNP:748874853
505 505 a, g dbSNP:140167865
512 512 c, t dbSNP:148982201
517 517 -, c dbSNP:760134827
517 517 c, t dbSNP:745841670
518 518 c, t dbSNP:771727704
524 524 a, g dbSNP:775273192
528 528 a, g dbSNP:138587317
545 545 a, g dbSNP:377693871
546 546 c, t dbSNP:200621180
547 547 a, g dbSNP:149344982
548 548 c, t dbSNP:527613008
551 551 a, g dbSNP:761836226
560 560 c, t dbSNP:143621566
561 561 a, g dbSNP:750842585
576 576 a, g dbSNP:760029254
577 577 g, t dbSNP:121918012
584 584 a, g dbSNP:750079676
586 586 c, t dbSNP:753392973
602 602 c, t dbSNP:373912990
604 604 a, g dbSNP:778232217
610 610 -, c dbSNP:750174638
617 617 c, t dbSNP:766504809
618 618 a, g dbSNP:121918019
620 620 c, t dbSNP:758330265
621 621 a, g dbSNP:199669988
623 623 c, g dbSNP:746782435
626 626 c, g, t dbSNP:201250289
627 627 a, g dbSNP:121918000
628 628 c, t dbSNP:748250829
632 632 c, t dbSNP:770068340
634 634 c, t dbSNP:199590449
642 642 c, t dbSNP:763159520
653 653 c, t dbSNP:771542770
656 656 a, t dbSNP:774949653
662 662 c, g, t dbSNP:760153868
663 663 a, g dbSNP:121918007
666 666 a, g dbSNP:761361696
667 667 c, t dbSNP:765011829
669 669 -, c dbSNP:758124823
674 674 c, t dbSNP:112063292
698 698 a, g dbSNP:200597048
702 702 a, t dbSNP:374558572
704 704 c, t dbSNP:141448778
705 705 a, g dbSNP:751455369
707 707 c, t dbSNP:754911877
709 709 a, c dbSNP:780790767
712 712 a, c dbSNP:121918004
721 721 a, g dbSNP:748031071
735 735 a, g dbSNP:769903299
740 740 c, t dbSNP:201739155
741 741 -, c dbSNP:781213038
742 742 -, aa dbSNP:748254075
742 742 c, t dbSNP:777699004
745 745 a, t dbSNP:746014071
747 747 a, g dbSNP:772432010
749 749 -, g dbSNP:769948289
749 749 g, t dbSNP:776117933
750 750 a, g dbSNP:747488546
753 753 c, g dbSNP:769020799
754 754 c, g, t dbSNP:566317085
759 759 c, t dbSNP:766076920
760 760 a, g dbSNP:199665722
765 765 c, t dbSNP:759125473
768 768 a, c dbSNP:767334437
769 769 c, t dbSNP:752641050
776 776 c, t dbSNP:369550359
779 779 g, t dbSNP:763892146
783 783 a, g dbSNP:746933644
784 784 a, g dbSNP:757551727
793 793 c, t dbSNP:779322468
794 794 g, t dbSNP:745924139
798 798 c, t dbSNP:758451024
799 799 a, g dbSNP:533959092
809 809 c, t dbSNP:780024242
819 819 a, c dbSNP:747480886
826 826 c, t dbSNP:142608957
827 827 a, g dbSNP:776965688
836 836 c, t dbSNP:188689330
837 837 a, g dbSNP:770539523
838 838 c, g, t dbSNP:121918018
843 843 a, g dbSNP:781403334
849 849 a, c, g dbSNP:151270365
850 850 a, t dbSNP:774877541
860 860 a, g dbSNP:760649979
865 865 a, g dbSNP:764197078
866 866 c, t dbSNP:753656794
873 873 a, c dbSNP:761753019
874 874 a, c, t dbSNP:765149569
875 875 a, g dbSNP:537483743
879 879 c, t dbSNP:3200254
883 883 a, g dbSNP:786204442
894 894 c, t dbSNP:751625937
901 901 a, g dbSNP:786204634
906 906 c, t dbSNP:121918020
907 907 a, g, t dbSNP:781272386
910 910 c, t dbSNP:148405563
911 911 a, g dbSNP:372247799
913 913 -, a dbSNP:771175614
915 915 c, g dbSNP:749684443
930 930 a, c dbSNP:771727865
938 938 c, t dbSNP:779625059
942 942 c, g dbSNP:746700357
950 950 a, g dbSNP:375027534
951 951 c, t dbSNP:141742288
956 956 c, t dbSNP:754262699
962 962 c, t dbSNP:779115195
963 963 a, g dbSNP:786204473
966 966 a, c, t dbSNP:765458125
968 968 a, g dbSNP:3200255
973 973 a, c dbSNP:121918002
979 979 a, t dbSNP:747637927
983 983 a, c dbSNP:755529290
984 984 a, g dbSNP:121918017
994 994 -, g dbSNP:768160006
995 995 a, g dbSNP:749112407
998 998 a, c, g dbSNP:560308330
1002 1002 a, g dbSNP:745704006
1006 1006 c, t dbSNP:146908399
1007 1007 a, g dbSNP:527465409
1010 1010 c, t dbSNP:373257447
1012 1012 c, t dbSNP:768555495
1015 1015 a, c, t dbSNP:376221105
1019 1019 c, t dbSNP:762210096
1020 1020 a, t dbSNP:765836269
1022 1022 c, t dbSNP:750783677
1023 1023 a, g dbSNP:763457259
1027 1027 -, tgg dbSNP:756329108
1029 1029 c, g dbSNP:552250079
1044 1044 a, c dbSNP:752356218
1050 1050 c, g dbSNP:755795919
1053 1053 c, t dbSNP:200133602
1054 1054 a, g dbSNP:138679161
1055 1055 a, g dbSNP:757111696
1058 1058 a, g dbSNP:778873231
1069 1069 g, t dbSNP:745830614
1070 1070 -, ctt dbSNP:753338851
1071 1071 c, t dbSNP:121918010
1072 1072 g, t dbSNP:779832611
1082 1082 a, g dbSNP:747146797
1086 1086 a, g dbSNP:768976020
1092 1092 a, g dbSNP:769955594
1093 1093 a, g dbSNP:121918009
1094 1094 c, t dbSNP:370122334
1106 1106 -, g dbSNP:764908423
1106 1106 c, t dbSNP:147688908
1111 1111 a, t dbSNP:763800165
1139 1139 g, t dbSNP:771632536
1148 1148 a, g, t dbSNP:774824768
1160 1160 c, g dbSNP:767794155
1161 1161 c, t dbSNP:776304194
1162 1162 a, g dbSNP:202022405
1169 1169 c, t dbSNP:567349821
1170 1170 a, g dbSNP:749989499
1193 1193 c, t dbSNP:758332051
1195 1195 c, t dbSNP:368809478
1204 1204 c, t dbSNP:751292739
1208 1208 c, g dbSNP:200153944
1211 1211 c, t dbSNP:112335417
1212 1212 a, g dbSNP:552831415
1214 1214 a, g dbSNP:748337342
1222 1222 c, t dbSNP:756418235
1223 1223 a, g dbSNP:777986840
1225 1225 a, t dbSNP:121918008
1231 1231 -, c dbSNP:758119185
1235 1235 c, t dbSNP:749419329
1236 1236 a, g dbSNP:771540767
1251 1251 a, g dbSNP:150594290
1257 1257 -, c dbSNP:751404811
1257 1257 a, g dbSNP:774870859
1258 1258 a, c dbSNP:746390776
1258 1258 -, c dbSNP:779683021
1259 1259 c, t dbSNP:772412576
1263 1263 c, t dbSNP:371243939
1268 1268 c, g dbSNP:375767924
1273 1273 -, t dbSNP:754826836
1274 1274 c, t dbSNP:764940488
1275 1275 a, g dbSNP:772682471
1276 1276 c, t dbSNP:751977466
1289 1289 c, t dbSNP:764010876
1293 1293 a, c dbSNP:754044587
1300 1300 a, c, g dbSNP:757564264
1319 1319 c, t dbSNP:750530891
1325 1325 c, t dbSNP:758911741
1326 1326 g, t dbSNP:780478066
1337 1337 c, t dbSNP:747539132
1342 1342 a, g dbSNP:121918014
1355 1355 c, t dbSNP:780762265
1366 1366 a, g dbSNP:781543452
1367 1367 c, t dbSNP:748883680
1368 1368 a, g dbSNP:770548228
1372 1372 a, c dbSNP:773907984
1374 1374 c, t dbSNP:759017288
1382 1382 c, t dbSNP:200330153
1395 1395 c, g dbSNP:771633915
1398 1398 c, t dbSNP:121918006
1400 1400 c, t dbSNP:775526490
1405 1405 -, aca dbSNP:771212957
1406 1406 c, t dbSNP:757045880
1408 1408 a, g dbSNP:368408859
1420 1420 a, c, g dbSNP:768053120
1421 1421 a, g dbSNP:756394364
1440 1440 c, t dbSNP:138690664
1441 1441 a, g dbSNP:150799088
1443 1443 c, t dbSNP:758125155
1445 1445 c, t dbSNP:377110098
1450 1450 -, c dbSNP:774529894
1454 1454 c, t dbSNP:746554462
1455 1455 a, g dbSNP:149889416
1457 1457 c, t dbSNP:370212283
1458 1458 a, g dbSNP:121918016
1458 1458 -, g dbSNP:746256993
1466 1466 c, t dbSNP:776664499
1472 1472 c, t dbSNP:371984578
1473 1473 a, g dbSNP:34810399
1489 1489 c, g dbSNP:773075737
1492 1492 c, t dbSNP:763073466
1495 1495 c, t dbSNP:766656419
1496 1496 a, g dbSNP:774384124
1498 1498 a, g dbSNP:759662331
1500 1500 c, t dbSNP:767614891
1508 1508 c, t dbSNP:369433931
1511 1511 a, c, t dbSNP:373417343
1512 1512 a, g dbSNP:376354718
1514 1514 c, t dbSNP:12027316
1517 1517 c, t dbSNP:183381346
1529 1529 c, t dbSNP:527657489
1532 1532 c, t dbSNP:540139632
1533 1533 c, t dbSNP:754502257
1536 1536 a, c dbSNP:780857373
1538 1538 c, t dbSNP:747980975
1540 1540 c, t dbSNP:769829312
1547 1547 a, g dbSNP:188443578
1556 1556 c, t dbSNP:749148162
1562 1562 c, t dbSNP:771120248
1568 1568 c, t dbSNP:774516408
1571 1571 c, t dbSNP:759758484
1572 1572 c, t dbSNP:772080508
1574 1574 c, t dbSNP:142545037
1575 1575 a, c, g dbSNP:761079751
1584 1584 a, g dbSNP:754125867
1590 1590 a, g dbSNP:762216748
1597 1597 c, t dbSNP:550358395
1598 1598 a, g dbSNP:751195005
1607 1607 a, c dbSNP:754694335
1618 1618 a, g, t dbSNP:79250591
1620 1620 c, t dbSNP:752320340
1623 1623 c, t dbSNP:755976886
1631 1631 c, t dbSNP:529786148
1632 1632 a, g dbSNP:367657406
1633 1633 c, t dbSNP:371373128
1634 1634 a, g, t dbSNP:3200256
1638 1638 a, g dbSNP:772346350
1647 1647 c, g, t dbSNP:775398905
1649 1649 a, c, g, t dbSNP:376020180
1651 1651 -, t dbSNP:387906525
1652 1652 a, g dbSNP:765641649
1654 1654 a, g dbSNP:368326384
1655 1655 c, g dbSNP:370978556
1656 1656 a, g dbSNP:372315234
1657 1657 c, t dbSNP:34605986
1666 1666 -, g dbSNP:764994176
1670 1670 g, t dbSNP:755602034
1672 1672 c, g dbSNP:763515495
1674 1674 a, g dbSNP:753716865
1678 1678 c, t dbSNP:757240883
1679 1679 c, t dbSNP:778673244
1680 1680 c, t dbSNP:559330654
1681 1681 a, g dbSNP:571140206
1684 1684 c, t dbSNP:780269910
1687 1687 c, t dbSNP:567336093
1692 1692 a, t dbSNP:747222706
1693 1693 a, g dbSNP:375281601
1696 1696 c, t dbSNP:768718338
1708 1708 c, t dbSNP:776868579
1710 1710 a, g dbSNP:748654072
1718 1718 a, c dbSNP:770493812
1727 1727 c, g dbSNP:367637559
1731 1731 a, c, g dbSNP:565251838
1732 1732 a, c, t dbSNP:1697405
1733 1733 a, c dbSNP:78043671
1733 1733 -, c dbSNP:371832452
1789 1789 -, c dbSNP:140511985
1790 1790 c, t dbSNP:553947949
1793 1793 a, g dbSNP:1697406
1809 1809 c, t dbSNP:545776624
1810 1810 g, t dbSNP:766588843
1816 1816 c, t dbSNP:564863879
1818 1818 c, t dbSNP:532269853
1845 1845 a, g dbSNP:776773091
1871 1871 c, t dbSNP:116162120
1884 1884 c, t dbSNP:373909118
1885 1885 a, g dbSNP:529801718
1900 1900 a, c dbSNP:1772719
1925 1925 c, t dbSNP:765353111
1928 1928 a, c dbSNP:751503180
1929 1929 c, g dbSNP:566407347
1939 1939 g, t dbSNP:527314874
1943 1943 g, t dbSNP:552201420
1954 1954 a, g dbSNP:757243859
1972 1972 c, t dbSNP:76073898
1987 1987 a, g dbSNP:750252193
2004 2004 a, g dbSNP:538549134
2029 2029 a, g dbSNP:556534930
2055 2055 c, t dbSNP:2242420
2068 2068 -, ctc dbSNP:531742327
2100 2100 a, g dbSNP:2242421
2127 2127 a, g dbSNP:114552089
2140 2140 g, t dbSNP:536009840
2147 2147 a, c dbSNP:138564953
2215 2215 c, t dbSNP:754489263
2242 2242 c, t dbSNP:141554698
2255 2255 a, g dbSNP:778461715
2261 2261 a, g dbSNP:747561664
2304 2304 a, g dbSNP:111947234
2330 2330 c, g dbSNP:145193027
2347 2347 a, g dbSNP:562609652
2352 2352 -, t dbSNP:200291738
2352 2352 a, t dbSNP:78801483
2359 2359 c, t dbSNP:541640914
2364 2364 c, t dbSNP:41265991
2369 2369 -, tgg dbSNP:769940109
2416 2416 a, c dbSNP:139022638

Target ORF information:

RefSeq Version NM_001127501
Organism Homo sapiens (human)
Definition Homo sapiens alkaline phosphatase, liver/bone/kidney (ALPL), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001127501

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGTTCCTGG GAGATGGGAT GGGTGTCTCC ACAGTGACGG CTGCCCGCAT CCTCAAGGGT 
CAGCTCCACC ACAACCCTGG GGAGGAGACC AGGCTGGAGA TGGACAAGTT CCCCTTCGTG
GCCCTCTCCA AGACGTACAA CACCAATGCC CAGGTCCCTG ACAGCGCCGG CACCGCCACC
GCCTACCTGT GTGGGGTGAA GGCCAATGAG GGCACCGTGG GGGTAAGCGC AGCCACTGAG
CGTTCCCGGT GCAACACCAC CCAGGGGAAC GAGGTCACCT CCATCCTGCG CTGGGCCAAG
GACGCTGGGA AATCTGTGGG CATTGTGACC ACCACGAGAG TGAACCATGC CACCCCCAGC
GCCGCCTACG CCCACTCGGC TGACCGGGAC TGGTACTCAG ACAACGAGAT GCCCCCTGAG
GCCTTGAGCC AGGGCTGTAA GGACATCGCC TACCAGCTCA TGCATAACAT CAGGGACATT
GACGTGATCA TGGGGGGTGG CCGGAAATAC ATGTACCCCA AGAATAAAAC TGATGTGGAG
TATGAGAGTG ACGAGAAAGC CAGGGGCACG AGGCTGGACG GCCTGGACCT CGTTGACACC
TGGAAGAGCT TCAAACCGAG ATACAAGCAC TCCCACTTCA TCTGGAACCG CACGGAACTC
CTGACCCTTG ACCCCCACAA TGTGGACTAC CTATTGGGTC TCTTCGAGCC AGGGGACATG
CAGTACGAGC TGAACAGGAA CAACGTGACG GACCCGTCAC TCTCCGAGAT GGTGGTGGTG
GCCATCCAGA TCCTGCGGAA GAACCCCAAA GGCTTCTTCT TGCTGGTGGA AGGAGGCAGA
ATTGACCACG GGCACCATGA AGGAAAAGCC AAGCAGGCCC TGCATGAGGC GGTGGAGATG
GACCGGGCCA TCGGGCAGGC AGGCAGCTTG ACCTCCTCGG AAGACACTCT GACCGTGGTC
ACTGCGGACC ATTCCCACGT CTTCACATTT GGTGGATACA CCCCCCGTGG CAACTCTATC
TTTGGTCTGG CCCCCATGCT GAGTGACACA GACAAGAAGC CCTTCACTGC CATCCTGTAT
GGCAATGGGC CTGGCTACAA GGTGGTGGGC GGTGAACGAG AGAATGTCTC CATGGTGGAC
TATGCTCACA ACAACTACCA GGCGCAGTCT GCTGTGCCCC TGCGCCACGA GACCCACGGC
GGGGAGGACG TGGCCGTCTT CTCCAAGGGC CCCATGGCGC ACCTGCTGCA CGGCGTCCAC
GAGCAGAACT ACGTCCCCCA CGTGATGGCG TATGCAGCCT GCATCGGGGC CAACCTCGGC
CACTGTGCTC CTGCCAGCTC GGCAGGCAGC CTTGCTGCAG GCCCCCTGCT GCTCGCGCTG
GCCCTCTACC CCCTGAGCGT CCTGTTCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu23043
Accession Version NM_001177520.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1344bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product alkaline phosphatase, tissue-nonspecific isozyme isoform 3
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CN425768.1, DA574668.1, AK295608.1, BC021289.2 and AL359815.26. Summary: There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization; however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to hypophosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of this disorder can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms. Alternatively spliced transcript variants have been described. [provided by RefSeq, Apr 2010]. Transcript Variant: This variant (3) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. This variant also lacks an exon in the 5' coding region, compared to variant 1. The encoded isoform (3) has a unique N-terminus and is shorter than isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK295608.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2146236, SAMEA2159764 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
ATGCCCTGGA GCTTCAGAAG CTCAACACCA ACGTGGCTAA GAATGTCATC ATGTTCCTGG 
GAGATGACGT ACAACACCAA TGCCCAGGTC CCTGACAGCG CCGGCACCGC CACCGCCTAC
CTGTGTGGGG TGAAGGCCAA TGAGGGCACC GTGGGGGTAA GCGCAGCCAC TGAGCGTTCC
CGGTGCAACA CCACCCAGGG GAACGAGGTC ACCTCCATCC TGCGCTGGGC CAAGGACGCT
GGGAAATCTG TGGGCATTGT GACCACCACG AGAGTGAACC ATGCCACCCC CAGCGCCGCC
TACGCCCACT CGGCTGACCG GGACTGGTAC TCAGACAACG AGATGCCCCC TGAGGCCTTG
AGCCAGGGCT GTAAGGACAT CGCCTACCAG CTCATGCATA ACATCAGGGA CATTGACGTG
ATCATGGGGG GTGGCCGGAA ATACATGTAC CCCAAGAATA AAACTGATGT GGAGTATGAG
AGTGACGAGA AAGCCAGGGG CACGAGGCTG GACGGCCTGG ACCTCGTTGA CACCTGGAAG
AGCTTCAAAC CGAGATACAA GCACTCCCAC TTCATCTGGA ACCGCACGGA ACTCCTGACC
CTTGACCCCC ACAATGTGGA CTACCTATTG GGTCTCTTCG AGCCAGGGGA CATGCAGTAC
GAGCTGAACA GGAACAACGT GACGGACCCG TCACTCTCCG AGATGGTGGT GGTGGCCATC
CAGATCCTGC GGAAGAACCC CAAAGGCTTC TTCTTGCTGG TGGAAGGAGG CAGAATTGAC
CACGGGCACC ATGAAGGAAA AGCCAAGCAG GCCCTGCATG AGGCGGTGGA GATGGACCGG
GCCATCGGGC AGGCAGGCAG CTTGACCTCC TCGGAAGACA CTCTGACCGT GGTCACTGCG
GACCATTCCC ACGTCTTCAC ATTTGGTGGA TACACCCCCC GTGGCAACTC TATCTTTGGT
CTGGCCCCCA TGCTGAGTGA CACAGACAAG AAGCCCTTCA CTGCCATCCT GTATGGCAAT
GGGCCTGGCT ACAAGGTGGT GGGCGGTGAA CGAGAGAATG TCTCCATGGT GGACTATGCT
CACAACAACT ACCAGGCGCA GTCTGCTGTG CCCCTGCGCC ACGAGACCCA CGGCGGGGAG
GACGTGGCCG TCTTCTCCAA GGGCCCCATG GCGCACCTGC TGCACGGCGT CCACGAGCAG
AACTACGTCC CCCACGTGAT GGCGTATGCA GCCTGCATCG GGGCCAACCT CGGCCACTGT
GCTCCTGCCA GCTCGGCAGG CAGCCTTGCT GCAGGCCCCC TGCTGCTCGC GCTGGCCCTC
TACCCCCTGA GCGTCCTGTT CTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqNP_001170991.1
CDS208..1551
Misc Feature(1)202..204(+)
Misc Feature(2)271..1446(+)
Misc Feature(3)271..1422(+)
Misc Feature(4)301..1338(+)
Exon (1)1..153
Gene:ALPL
Gene Synonym:
Exon (2)154..273
Gene:ALPL
Gene Synonym:
Exon (3)274..448
Gene:ALPL
Gene Synonym:
Exon (4)449..624
Gene:ALPL
Gene Synonym:
Exon (5)625..768
Gene:ALPL
Gene Synonym:
Exon (6)769..838
Gene:ALPL
Gene Synonym:
Exon (7)839..973
Gene:ALPL
Gene Synonym:
Exon (8)974..1165
Gene:ALPL
Gene Synonym:
Exon (9)1166..1285
Gene:ALPL
Gene Synonym:
Exon (10)1286..2315
Gene:ALPL
Gene Synonym:
Translation
Position Chain Variation Link
5 5 a, g dbSNP:554887643
64 64 c, g dbSNP:111601456
74 74 c, t dbSNP:371922238
165 165 a, g dbSNP:766948855
170 170 c, t dbSNP:375342528
172 172 a, g dbSNP:146412299
176 176 c, t dbSNP:144632001
181 181 a, g dbSNP:753550135
183 183 a, g dbSNP:757127456
190 190 c, g, t dbSNP:121918005
191 191 a, g dbSNP:772424729
193 193 a, g dbSNP:780221572
198 198 a, g dbSNP:747167000
199 199 c, t dbSNP:199952414
202 202 c, t dbSNP:143358506
203 203 a, g dbSNP:769035516
208 208 a, g dbSNP:777235122
209 209 c, t dbSNP:748438719
211 211 c, t dbSNP:770093969
219 219 c, t dbSNP:148357203
220 220 -, t dbSNP:763244290
239 239 a, c, t dbSNP:539884496
240 240 a, g dbSNP:767216554
251 251 a, t dbSNP:774859071
253 253 -, tca dbSNP:766831104
258 258 a, g dbSNP:760272172
262 262 a, t dbSNP:763919659
263 263 c, t dbSNP:753763521
266 266 a, g dbSNP:757176737
276 276 a, g dbSNP:191778470
279 279 a, c dbSNP:746273959
283 283 a, g dbSNP:202075854
290 290 c, t dbSNP:768348242
299 299 c, t dbSNP:121918015
306 306 -, tgccggcac dbSNP:200166222
306 306 c, t dbSNP:1780316
307 307 a, g dbSNP:773257111
309 309 c, t dbSNP:769379537
315 315 c, t dbSNP:377453516
317 317 c, t dbSNP:762915678
321 321 c, t dbSNP:770785345
322 322 a, g dbSNP:121918013
332 332 c, g dbSNP:774193109
334 334 -, gg dbSNP:751994699
345 345 a, c dbSNP:201342272
347 347 a, g dbSNP:11586344
351 351 a, g dbSNP:752868525
356 356 a, c dbSNP:146517700
357 357 c, t dbSNP:368714904
360 360 c, g dbSNP:764097939
364 364 a, g dbSNP:753929700
370 370 a, g dbSNP:757771793
374 374 c, g dbSNP:184095519
375 375 c, t dbSNP:750766317
376 376 ac, ca dbSNP:786204530
376 376 a, c dbSNP:758734017
377 377 a, c dbSNP:780583917
382 382 a, c, t dbSNP:747762186
383 383 a, g dbSNP:121918011
388 388 c, t dbSNP:748874853
389 389 a, g dbSNP:140167865
396 396 c, t dbSNP:148982201
401 401 -, c dbSNP:760134827
401 401 c, t dbSNP:745841670
402 402 c, t dbSNP:771727704
408 408 a, g dbSNP:775273192
412 412 a, g dbSNP:138587317
429 429 a, g dbSNP:377693871
430 430 c, t dbSNP:200621180
431 431 a, g dbSNP:149344982
432 432 c, t dbSNP:527613008
435 435 a, g dbSNP:761836226
444 444 c, t dbSNP:143621566
445 445 a, g dbSNP:750842585
460 460 a, g dbSNP:760029254
461 461 g, t dbSNP:121918012
468 468 a, g dbSNP:750079676
470 470 c, t dbSNP:753392973
486 486 c, t dbSNP:373912990
488 488 a, g dbSNP:778232217
494 494 -, c dbSNP:750174638
501 501 c, t dbSNP:766504809
502 502 a, g dbSNP:121918019
504 504 c, t dbSNP:758330265
505 505 a, g dbSNP:199669988
507 507 c, g dbSNP:746782435
510 510 c, g, t dbSNP:201250289
511 511 a, g dbSNP:121918000
512 512 c, t dbSNP:748250829
516 516 c, t dbSNP:770068340
518 518 c, t dbSNP:199590449
526 526 c, t dbSNP:763159520
537 537 c, t dbSNP:771542770
540 540 a, t dbSNP:774949653
546 546 c, g, t dbSNP:760153868
547 547 a, g dbSNP:121918007
550 550 a, g dbSNP:761361696
551 551 c, t dbSNP:765011829
553 553 -, c dbSNP:758124823
558 558 c, t dbSNP:112063292
582 582 a, g dbSNP:200597048
586 586 a, t dbSNP:374558572
588 588 c, t dbSNP:141448778
589 589 a, g dbSNP:751455369
591 591 c, t dbSNP:754911877
593 593 a, c dbSNP:780790767
596 596 a, c dbSNP:121918004
605 605 a, g dbSNP:748031071
619 619 a, g dbSNP:769903299
624 624 c, t dbSNP:201739155
625 625 -, c dbSNP:781213038
626 626 -, aa dbSNP:748254075
626 626 c, t dbSNP:777699004
629 629 a, t dbSNP:746014071
631 631 a, g dbSNP:772432010
633 633 -, g dbSNP:769948289
633 633 g, t dbSNP:776117933
634 634 a, g dbSNP:747488546
637 637 c, g dbSNP:769020799
638 638 c, g, t dbSNP:566317085
643 643 c, t dbSNP:766076920
644 644 a, g dbSNP:199665722
649 649 c, t dbSNP:759125473
652 652 a, c dbSNP:767334437
653 653 c, t dbSNP:752641050
660 660 c, t dbSNP:369550359
663 663 g, t dbSNP:763892146
667 667 a, g dbSNP:746933644
668 668 a, g dbSNP:757551727
677 677 c, t dbSNP:779322468
678 678 g, t dbSNP:745924139
682 682 c, t dbSNP:758451024
683 683 a, g dbSNP:533959092
693 693 c, t dbSNP:780024242
703 703 a, c dbSNP:747480886
710 710 c, t dbSNP:142608957
711 711 a, g dbSNP:776965688
720 720 c, t dbSNP:188689330
721 721 a, g dbSNP:770539523
722 722 c, g, t dbSNP:121918018
727 727 a, g dbSNP:781403334
733 733 a, c, g dbSNP:151270365
734 734 a, t dbSNP:774877541
744 744 a, g dbSNP:760649979
749 749 a, g dbSNP:764197078
750 750 c, t dbSNP:753656794
757 757 a, c dbSNP:761753019
758 758 a, c, t dbSNP:765149569
759 759 a, g dbSNP:537483743
763 763 c, t dbSNP:3200254
767 767 a, g dbSNP:786204442
778 778 c, t dbSNP:751625937
785 785 a, g dbSNP:786204634
790 790 c, t dbSNP:121918020
791 791 a, g, t dbSNP:781272386
794 794 c, t dbSNP:148405563
795 795 a, g dbSNP:372247799
797 797 -, a dbSNP:771175614
799 799 c, g dbSNP:749684443
814 814 a, c dbSNP:771727865
822 822 c, t dbSNP:779625059
826 826 c, g dbSNP:746700357
834 834 a, g dbSNP:375027534
835 835 c, t dbSNP:141742288
840 840 c, t dbSNP:754262699
846 846 c, t dbSNP:779115195
847 847 a, g dbSNP:786204473
850 850 a, c, t dbSNP:765458125
852 852 a, g dbSNP:3200255
857 857 a, c dbSNP:121918002
863 863 a, t dbSNP:747637927
867 867 a, c dbSNP:755529290
868 868 a, g dbSNP:121918017
878 878 -, g dbSNP:768160006
879 879 a, g dbSNP:749112407
882 882 a, c, g dbSNP:560308330
886 886 a, g dbSNP:745704006
890 890 c, t dbSNP:146908399
891 891 a, g dbSNP:527465409
894 894 c, t dbSNP:373257447
896 896 c, t dbSNP:768555495
899 899 a, c, t dbSNP:376221105
903 903 c, t dbSNP:762210096
904 904 a, t dbSNP:765836269
906 906 c, t dbSNP:750783677
907 907 a, g dbSNP:763457259
911 911 -, tgg dbSNP:756329108
913 913 c, g dbSNP:552250079
928 928 a, c dbSNP:752356218
934 934 c, g dbSNP:755795919
937 937 c, t dbSNP:200133602
938 938 a, g dbSNP:138679161
939 939 a, g dbSNP:757111696
942 942 a, g dbSNP:778873231
953 953 g, t dbSNP:745830614
954 954 -, ctt dbSNP:753338851
955 955 c, t dbSNP:121918010
956 956 g, t dbSNP:779832611
966 966 a, g dbSNP:747146797
970 970 a, g dbSNP:768976020
976 976 a, g dbSNP:769955594
977 977 a, g dbSNP:121918009
978 978 c, t dbSNP:370122334
990 990 -, g dbSNP:764908423
990 990 c, t dbSNP:147688908
995 995 a, t dbSNP:763800165
1023 1023 g, t dbSNP:771632536
1032 1032 a, g, t dbSNP:774824768
1044 1044 c, g dbSNP:767794155
1045 1045 c, t dbSNP:776304194
1046 1046 a, g dbSNP:202022405
1053 1053 c, t dbSNP:567349821
1054 1054 a, g dbSNP:749989499
1077 1077 c, t dbSNP:758332051
1079 1079 c, t dbSNP:368809478
1088 1088 c, t dbSNP:751292739
1092 1092 c, g dbSNP:200153944
1095 1095 c, t dbSNP:112335417
1096 1096 a, g dbSNP:552831415
1098 1098 a, g dbSNP:748337342
1106 1106 c, t dbSNP:756418235
1107 1107 a, g dbSNP:777986840
1109 1109 a, t dbSNP:121918008
1115 1115 -, c dbSNP:758119185
1119 1119 c, t dbSNP:749419329
1120 1120 a, g dbSNP:771540767
1135 1135 a, g dbSNP:150594290
1141 1141 -, c dbSNP:751404811
1141 1141 a, g dbSNP:774870859
1142 1142 a, c dbSNP:746390776
1142 1142 -, c dbSNP:779683021
1143 1143 c, t dbSNP:772412576
1147 1147 c, t dbSNP:371243939
1152 1152 c, g dbSNP:375767924
1157 1157 -, t dbSNP:754826836
1158 1158 c, t dbSNP:764940488
1159 1159 a, g dbSNP:772682471
1160 1160 c, t dbSNP:751977466
1173 1173 c, t dbSNP:764010876
1177 1177 a, c dbSNP:754044587
1184 1184 a, c, g dbSNP:757564264
1203 1203 c, t dbSNP:750530891
1209 1209 c, t dbSNP:758911741
1210 1210 g, t dbSNP:780478066
1221 1221 c, t dbSNP:747539132
1226 1226 a, g dbSNP:121918014
1239 1239 c, t dbSNP:780762265
1250 1250 a, g dbSNP:781543452
1251 1251 c, t dbSNP:748883680
1252 1252 a, g dbSNP:770548228
1256 1256 a, c dbSNP:773907984
1258 1258 c, t dbSNP:759017288
1266 1266 c, t dbSNP:200330153
1279 1279 c, g dbSNP:771633915
1282 1282 c, t dbSNP:121918006
1284 1284 c, t dbSNP:775526490
1289 1289 -, aca dbSNP:771212957
1290 1290 c, t dbSNP:757045880
1292 1292 a, g dbSNP:368408859
1304 1304 a, c, g dbSNP:768053120
1305 1305 a, g dbSNP:756394364
1324 1324 c, t dbSNP:138690664
1325 1325 a, g dbSNP:150799088
1327 1327 c, t dbSNP:758125155
1329 1329 c, t dbSNP:377110098
1334 1334 -, c dbSNP:774529894
1338 1338 c, t dbSNP:746554462
1339 1339 a, g dbSNP:149889416
1341 1341 c, t dbSNP:370212283
1342 1342 a, g dbSNP:121918016
1342 1342 -, g dbSNP:746256993
1350 1350 c, t dbSNP:776664499
1356 1356 c, t dbSNP:371984578
1357 1357 a, g dbSNP:34810399
1373 1373 c, g dbSNP:773075737
1376 1376 c, t dbSNP:763073466
1379 1379 c, t dbSNP:766656419
1380 1380 a, g dbSNP:774384124
1382 1382 a, g dbSNP:759662331
1384 1384 c, t dbSNP:767614891
1392 1392 c, t dbSNP:369433931
1395 1395 a, c, t dbSNP:373417343
1396 1396 a, g dbSNP:376354718
1398 1398 c, t dbSNP:12027316
1401 1401 c, t dbSNP:183381346
1413 1413 c, t dbSNP:527657489
1416 1416 c, t dbSNP:540139632
1417 1417 c, t dbSNP:754502257
1420 1420 a, c dbSNP:780857373
1422 1422 c, t dbSNP:747980975
1424 1424 c, t dbSNP:769829312
1431 1431 a, g dbSNP:188443578
1440 1440 c, t dbSNP:749148162
1446 1446 c, t dbSNP:771120248
1452 1452 c, t dbSNP:774516408
1455 1455 c, t dbSNP:759758484
1456 1456 c, t dbSNP:772080508
1458 1458 c, t dbSNP:142545037
1459 1459 a, c, g dbSNP:761079751
1468 1468 a, g dbSNP:754125867
1474 1474 a, g dbSNP:762216748
1481 1481 c, t dbSNP:550358395
1482 1482 a, g dbSNP:751195005
1491 1491 a, c dbSNP:754694335
1502 1502 a, g, t dbSNP:79250591
1504 1504 c, t dbSNP:752320340
1507 1507 c, t dbSNP:755976886
1515 1515 c, t dbSNP:529786148
1516 1516 a, g dbSNP:367657406
1517 1517 c, t dbSNP:371373128
1518 1518 a, g, t dbSNP:3200256
1522 1522 a, g dbSNP:772346350
1531 1531 c, g, t dbSNP:775398905
1533 1533 a, c, g, t dbSNP:376020180
1535 1535 -, t dbSNP:387906525
1536 1536 a, g dbSNP:765641649
1538 1538 a, g dbSNP:368326384
1539 1539 c, g dbSNP:370978556
1540 1540 a, g dbSNP:372315234
1541 1541 c, t dbSNP:34605986
1550 1550 -, g dbSNP:764994176
1554 1554 g, t dbSNP:755602034
1556 1556 c, g dbSNP:763515495
1558 1558 a, g dbSNP:753716865
1562 1562 c, t dbSNP:757240883
1563 1563 c, t dbSNP:778673244
1564 1564 c, t dbSNP:559330654
1565 1565 a, g dbSNP:571140206
1568 1568 c, t dbSNP:780269910
1571 1571 c, t dbSNP:567336093
1576 1576 a, t dbSNP:747222706
1577 1577 a, g dbSNP:375281601
1580 1580 c, t dbSNP:768718338
1592 1592 c, t dbSNP:776868579
1594 1594 a, g dbSNP:748654072
1602 1602 a, c dbSNP:770493812
1611 1611 c, g dbSNP:367637559
1615 1615 a, c, g dbSNP:565251838
1616 1616 a, c, t dbSNP:1697405
1617 1617 a, c dbSNP:78043671
1617 1617 -, c dbSNP:371832452
1673 1673 -, c dbSNP:140511985
1674 1674 c, t dbSNP:553947949
1677 1677 a, g dbSNP:1697406
1693 1693 c, t dbSNP:545776624
1694 1694 g, t dbSNP:766588843
1700 1700 c, t dbSNP:564863879
1702 1702 c, t dbSNP:532269853
1729 1729 a, g dbSNP:776773091
1755 1755 c, t dbSNP:116162120
1768 1768 c, t