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GABRA1 cDNA ORF clone, Homo sapiens (human)

Gene Symbol GABRA1
Entrez Gene ID 2554
Full Name gamma-aminobutyric acid (GABA) A receptor, alpha 1
Synonyms ECA4, EIEE19, EJM, EJM5
General protein information
Preferred Names
gamma-aminobutyric acid receptor subunit alpha-1
Names
gamma-aminobutyric acid receptor subunit alpha-1
GABA(A) receptor, alpha 1
GABA(A) receptor subunit alpha-1
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

5

5q34

Summary This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene cause juvenile myoclonic epilepsy and childhood absence epilepsy type 4. Multiple transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

137160

Disorder Html: {Epilepsy, juvenile myoclonic, susceptibility to, 5}, 611136 (3);

mRNA and Protein(s)

mRNA Protein Name
NM_000806 NP_000797 gamma-aminobutyric acid receptor subunit alpha-1 precursor
NM_001127643 NP_001121115 gamma-aminobutyric acid receptor subunit alpha-1 precursor
NM_001127644 NP_001121116 gamma-aminobutyric acid receptor subunit alpha-1 precursor
NM_001127645 NP_001121117 gamma-aminobutyric acid receptor subunit alpha-1 precursor
NM_001127648 NP_001121120 gamma-aminobutyric acid receptor subunit alpha-1 precursor



Homo sapiens (human) GABRA1 NP_000797.2
Pan troglodytes (chimpanzee) GABRA1 XP_001144644.2
Macaca mulatta (Rhesus monkey) GABRA1 XP_002804660.1
Canis lupus familiaris (dog) LOC489143 XP_546261.2
Bos taurus (cattle) GABRA1 NP_001178048.1
Mus musculus (house mouse) Gabra1 NP_034380.1
Rattus norvegicus (Norway rat) Gabra1 NP_899155.1
Gallus gallus (chicken) GABRA1 NP_989649.1
Danio rerio (zebrafish) gabra1 NP_001070794.1
Xenopus (Silurana) tropicalis (western clawed frog) gabra1 XP_002941682.2


GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following GABRA1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GABRA1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu26115
NM_000806 Homo sapiens gamma-aminobutyric acid (GABA) A receptor, alpha 1 (GABRA1), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$189.50-$265.30
$379.00
OHu26115
NM_001127643 Homo sapiens gamma-aminobutyric acid (GABA) A receptor, alpha 1 (GABRA1), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$189.50-$265.30
$379.00
OHu26115
NM_001127644 Homo sapiens gamma-aminobutyric acid (GABA) A receptor, alpha 1 (GABRA1), transcript variant 3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$189.50-$265.30
$379.00
OHu26115
NM_001127645 Homo sapiens gamma-aminobutyric acid (GABA) A receptor, alpha 1 (GABRA1), transcript variant 4, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$189.50-$265.30
$379.00
OHu26115
NM_001127648 Homo sapiens gamma-aminobutyric acid (GABA) A receptor, alpha 1 (GABRA1), transcript variant 7, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$189.50-$265.30
$379.00
Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
5 or more Clone 50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu26115
Clone ID Related Accession (Same CDS sequence) NM_000806 , NM_001127643 , NM_001127644 , NM_001127645 , NM_001127648
Accession Version NM_000806.5 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1371bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product gamma-aminobutyric acid receptor subunit alpha-1 precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK289792.1, X14766.1 and AC021079.4. This sequence is a reference standard in the RefSeqGene project. On May 24, 2008 this sequence version replaced gi:156071483. Transcript Variant: This variant (1) uses the 5'-most alternate exon in the 5' UTR. Variants 1-7 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK289792.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145743, SAMEA2154665 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
ATGAGGAAAA GTCCAGGTCT GTCTGACTGT CTTTGGGCCT GGATCCTCCT TCTGAGCACA 
CTGACTGGAA GAAGCTATGG ACAGCCGTCA TTACAAGATG AACTTAAAGA CAATACCACT
GTCTTCACCA GGATTTTGGA CAGACTCCTA GATGGTTATG ACAATCGCCT GAGACCAGGA
TTGGGAGAGC GTGTAACCGA AGTGAAGACT GATATCTTCG TCACCAGTTT CGGACCCGTT
TCAGACCATG ATATGGAATA TACAATAGAT GTATTTTTCC GTCAAAGCTG GAAGGATGAA
AGGTTAAAAT TTAAAGGACC TATGACAGTC CTCCGGTTAA ATAACCTAAT GGCAAGTAAA
ATCTGGACTC CGGACACATT TTTCCACAAT GGAAAGAAGT CAGTGGCCCA CAACATGACC
ATGCCCAACA AACTCCTGCG GATCACAGAG GATGGCACCT TGCTGTACAC CATGAGGCTG
ACAGTGAGAG CTGAATGTCC GATGCATTTG GAGGACTTCC CTATGGATGC CCATGCTTGC
CCACTAAAAT TTGGAAGTTA TGCTTATACA AGAGCAGAAG TTGTTTATGA ATGGACCAGA
GAGCCAGCAC GCTCAGTGGT TGTAGCAGAA GATGGATCAC GTCTAAACCA GTATGACCTT
CTTGGACAAA CAGTAGACTC TGGAATTGTC CAGTCAAGTA CAGGAGAATA TGTTGTTATG
ACCACTCATT TCCACTTGAA GAGAAAGATT GGCTACTTTG TTATTCAAAC ATACCTGCCA
TGCATAATGA CAGTGATTCT CTCACAAGTC TCCTTCTGGC TCAACAGAGA GTCTGTACCA
GCAAGAACTG TCTTTGGAGT AACAACTGTG CTCACCATGA CAACATTGAG CATCAGTGCC
AGAAACTCCC TCCCTAAGGT GGCTTATGCA ACAGCTATGG ATTGGTTTAT TGCCGTGTGC
TATGCCTTTG TGTTCTCAGC TCTGATTGAG TTTGCCACAG TAAACTATTT CACTAAGAGA
GGTTATGCAT GGGATGGCAA AAGTGTGGTT CCAGAAAAGC CAAAGAAAGT AAAGGATCCT
CTTATTAAGA AAAACAACAC TTACGCTCCA ACAGCAACCA GCTACACCCC TAATTTGGCC
AGGGGCGACC CGGGCTTAGC CACCATTGCT AAAAGTGCAA CCATAGAACC TAAAGAGGTC
AAGCCCGAAA CAAAACCACC AGAACCCAAG AAAACCTTTA ACAGTGTCAG CAAAATTGAC
CGACTGTCAA GAATAGCCTT CCCGCTGCTA TTTGGAATCT TTAACTTAGT CTACTGGGCT
ACGTATTTAA ACAGAGAGCC TCAGCTAAAA GCCCCCACAC CACATCAATA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_000797.2
CDS469..1839
Misc Feature(1)451..453(+)
Misc Feature(2)508..1794(+)
Misc Feature(3)595..1218(+)
Misc Feature(4)1222..1287(+)
Misc Feature(5)1237..1785(+)
Misc Feature(6)1303..1368(+)
Misc Feature(7)1405..1470(+)
Misc Feature(8)1732..1797(+)
Exon (1)1..221
Gene:GABRA1
Gene Synonym:
Exon (2)222..453
Gene:GABRA1
Gene Synonym:
Exon (3)454..542
Gene:GABRA1
Gene Synonym:
Exon (4)543..655
Gene:GABRA1
Gene Synonym:
Exon (5)656..723
Gene:GABRA1
Gene Synonym:
Exon (6)724..944
Gene:GABRA1
Gene Synonym:
Exon (7)945..1027
Gene:GABRA1
Gene Synonym:
Exon (8)1028..1171
Gene:GABRA1
Gene Synonym:
Exon (9)1172..1324
Gene:GABRA1
Gene Synonym:
Exon (10)1325..1527
Gene:GABRA1
Gene Synonym:
Exon (11)1528..4376
Gene:GABRA1
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_000806
Organism Homo sapiens (human)
Definition Homo sapiens gamma-aminobutyric acid (GABA) A receptor, alpha 1 (GABRA1), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_000806

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
ATGAGGAAAA GTCCAGGTCT GTCTGACTGT CTTTGGGCCT GGATCCTCCT TCTGAGCACA 
CTGACTGGAA GAAGCTATGG ACAGCCGTCA TTACAAGATG AACTTAAAGA CAATACCACT
GTCTTCACCA GGATTTTGGA CAGACTCCTA GATGGTTATG ACAATCGCCT GAGACCAGGA
TTGGGAGAGC GTGTAACCGA AGTGAAGACT GATATCTTCG TCACCAGTTT CGGACCCGTT
TCAGACCATG ATATGGAATA TACAATAGAT GTATTTTTCC GTCAAAGCTG GAAGGATGAA
AGGTTAAAAT TTAAAGGACC TATGACAGTC CTCCGGTTAA ATAACCTAAT GGCAAGTAAA
ATCTGGACTC CGGACACATT TTTCCACAAT GGAAAGAAGT CAGTGGCCCA CAACATGACC
ATGCCCAACA AACTCCTGCG GATCACAGAG GATGGCACCT TGCTGTACAC CATGAGGCTG
ACAGTGAGAG CTGAATGTCC GATGCATTTG GAGGACTTCC CTATGGATGC CCATGCTTGC
CCACTAAAAT TTGGAAGTTA TGCTTATACA AGAGCAGAAG TTGTTTATGA ATGGACCAGA
GAGCCAGCAC GCTCAGTGGT TGTAGCAGAA GATGGATCAC GTCTAAACCA GTATGACCTT
CTTGGACAAA CAGTAGACTC TGGAATTGTC CAGTCAAGTA CAGGAGAATA TGTTGTTATG
ACCACTCATT TCCACTTGAA GAGAAAGATT GGCTACTTTG TTATTCAAAC ATACCTGCCA
TGCATAATGA CAGTGATTCT CTCACAAGTC TCCTTCTGGC TCAACAGAGA GTCTGTACCA
GCAAGAACTG TCTTTGGAGT AACAACTGTG CTCACCATGA CAACATTGAG CATCAGTGCC
AGAAACTCCC TCCCTAAGGT GGCTTATGCA ACAGCTATGG ATTGGTTTAT TGCCGTGTGC
TATGCCTTTG TGTTCTCAGC TCTGATTGAG TTTGCCACAG TAAACTATTT CACTAAGAGA
GGTTATGCAT GGGATGGCAA AAGTGTGGTT CCAGAAAAGC CAAAGAAAGT AAAGGATCCT
CTTATTAAGA AAAACAACAC TTACGCTCCA ACAGCAACCA GCTACACCCC TAATTTGGCC
AGGGGCGACC CGGGCTTAGC CACCATTGCT AAAAGTGCAA CCATAGAACC TAAAGAGGTC
AAGCCCGAAA CAAAACCACC AGAACCCAAG AAAACCTTTA ACAGTGTCAG CAAAATTGAC
CGACTGTCAA GAATAGCCTT CCCGCTGCTA TTTGGAATCT TTAACTTAGT CTACTGGGCT
ACGTATTTAA ACAGAGAGCC TCAGCTAAAA GCCCCCACAC CACATCAATA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu26115
Clone ID Related Accession (Same CDS sequence) NM_000806 , NM_001127643 , NM_001127644 , NM_001127645 , NM_001127648
Accession Version NM_001127643.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1371bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product gamma-aminobutyric acid receptor subunit alpha-1 precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB485936.1, DB487114.1, X14766.1, R60404.1, X13584.1, DA228536.1 and AC021079.4. Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Variants 1-7 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: BC030696.1, AK289792.1 [ECO:0000331] RNAseq introns :: single sample supports all introns SAMEA962343 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
ATGAGGAAAA GTCCAGGTCT GTCTGACTGT CTTTGGGCCT GGATCCTCCT TCTGAGCACA 
CTGACTGGAA GAAGCTATGG ACAGCCGTCA TTACAAGATG AACTTAAAGA CAATACCACT
GTCTTCACCA GGATTTTGGA CAGACTCCTA GATGGTTATG ACAATCGCCT GAGACCAGGA
TTGGGAGAGC GTGTAACCGA AGTGAAGACT GATATCTTCG TCACCAGTTT CGGACCCGTT
TCAGACCATG ATATGGAATA TACAATAGAT GTATTTTTCC GTCAAAGCTG GAAGGATGAA
AGGTTAAAAT TTAAAGGACC TATGACAGTC CTCCGGTTAA ATAACCTAAT GGCAAGTAAA
ATCTGGACTC CGGACACATT TTTCCACAAT GGAAAGAAGT CAGTGGCCCA CAACATGACC
ATGCCCAACA AACTCCTGCG GATCACAGAG GATGGCACCT TGCTGTACAC CATGAGGCTG
ACAGTGAGAG CTGAATGTCC GATGCATTTG GAGGACTTCC CTATGGATGC CCATGCTTGC
CCACTAAAAT TTGGAAGTTA TGCTTATACA AGAGCAGAAG TTGTTTATGA ATGGACCAGA
GAGCCAGCAC GCTCAGTGGT TGTAGCAGAA GATGGATCAC GTCTAAACCA GTATGACCTT
CTTGGACAAA CAGTAGACTC TGGAATTGTC CAGTCAAGTA CAGGAGAATA TGTTGTTATG
ACCACTCATT TCCACTTGAA GAGAAAGATT GGCTACTTTG TTATTCAAAC ATACCTGCCA
TGCATAATGA CAGTGATTCT CTCACAAGTC TCCTTCTGGC TCAACAGAGA GTCTGTACCA
GCAAGAACTG TCTTTGGAGT AACAACTGTG CTCACCATGA CAACATTGAG CATCAGTGCC
AGAAACTCCC TCCCTAAGGT GGCTTATGCA ACAGCTATGG ATTGGTTTAT TGCCGTGTGC
TATGCCTTTG TGTTCTCAGC TCTGATTGAG TTTGCCACAG TAAACTATTT CACTAAGAGA
GGTTATGCAT GGGATGGCAA AAGTGTGGTT CCAGAAAAGC CAAAGAAAGT AAAGGATCCT
CTTATTAAGA AAAACAACAC TTACGCTCCA ACAGCAACCA GCTACACCCC TAATTTGGCC
AGGGGCGACC CGGGCTTAGC CACCATTGCT AAAAGTGCAA CCATAGAACC TAAAGAGGTC
AAGCCCGAAA CAAAACCACC AGAACCCAAG AAAACCTTTA ACAGTGTCAG CAAAATTGAC
CGACTGTCAA GAATAGCCTT CCCGCTGCTA TTTGGAATCT TTAACTTAGT CTACTGGGCT
ACGTATTTAA ACAGAGAGCC TCAGCTAAAA GCCCCCACAC CACATCAATA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001121115.1
CDS356..1726
Misc Feature(1)338..340(+)
Misc Feature(2)395..1681(+)
Misc Feature(3)482..1105(+)
Misc Feature(4)1109..1174(+)
Misc Feature(5)1124..1672(+)
Misc Feature(6)1190..1255(+)
Misc Feature(7)1292..1357(+)
Misc Feature(8)1619..1684(+)
Exon (1)1..108
Gene:GABRA1
Gene Synonym:
Exon (2)109..340
Gene:GABRA1
Gene Synonym:
Exon (3)341..429
Gene:GABRA1
Gene Synonym:
Exon (4)430..542
Gene:GABRA1
Gene Synonym:
Exon (5)543..610
Gene:GABRA1
Gene Synonym:
Exon (6)611..831
Gene:GABRA1
Gene Synonym:
Exon (7)832..914
Gene:GABRA1
Gene Synonym:
Exon (8)915..1058
Gene:GABRA1
Gene Synonym:
Exon (9)1059..1211
Gene:GABRA1
Gene Synonym:
Exon (10)1212..1414
Gene:GABRA1
Gene Synonym:
Exon (11)1415..4263
Gene:GABRA1
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001127643
Organism Homo sapiens (human)
Definition Homo sapiens gamma-aminobutyric acid (GABA) A receptor, alpha 1 (GABRA1), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001127643

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
ATGAGGAAAA GTCCAGGTCT GTCTGACTGT CTTTGGGCCT GGATCCTCCT TCTGAGCACA 
CTGACTGGAA GAAGCTATGG ACAGCCGTCA TTACAAGATG AACTTAAAGA CAATACCACT
GTCTTCACCA GGATTTTGGA CAGACTCCTA GATGGTTATG ACAATCGCCT GAGACCAGGA
TTGGGAGAGC GTGTAACCGA AGTGAAGACT GATATCTTCG TCACCAGTTT CGGACCCGTT
TCAGACCATG ATATGGAATA TACAATAGAT GTATTTTTCC GTCAAAGCTG GAAGGATGAA
AGGTTAAAAT TTAAAGGACC TATGACAGTC CTCCGGTTAA ATAACCTAAT GGCAAGTAAA
ATCTGGACTC CGGACACATT TTTCCACAAT GGAAAGAAGT CAGTGGCCCA CAACATGACC
ATGCCCAACA AACTCCTGCG GATCACAGAG GATGGCACCT TGCTGTACAC CATGAGGCTG
ACAGTGAGAG CTGAATGTCC GATGCATTTG GAGGACTTCC CTATGGATGC CCATGCTTGC
CCACTAAAAT TTGGAAGTTA TGCTTATACA AGAGCAGAAG TTGTTTATGA ATGGACCAGA
GAGCCAGCAC GCTCAGTGGT TGTAGCAGAA GATGGATCAC GTCTAAACCA GTATGACCTT
CTTGGACAAA CAGTAGACTC TGGAATTGTC CAGTCAAGTA CAGGAGAATA TGTTGTTATG
ACCACTCATT TCCACTTGAA GAGAAAGATT GGCTACTTTG TTATTCAAAC ATACCTGCCA
TGCATAATGA CAGTGATTCT CTCACAAGTC TCCTTCTGGC TCAACAGAGA GTCTGTACCA
GCAAGAACTG TCTTTGGAGT AACAACTGTG CTCACCATGA CAACATTGAG CATCAGTGCC
AGAAACTCCC TCCCTAAGGT GGCTTATGCA ACAGCTATGG ATTGGTTTAT TGCCGTGTGC
TATGCCTTTG TGTTCTCAGC TCTGATTGAG TTTGCCACAG TAAACTATTT CACTAAGAGA
GGTTATGCAT GGGATGGCAA AAGTGTGGTT CCAGAAAAGC CAAAGAAAGT AAAGGATCCT
CTTATTAAGA AAAACAACAC TTACGCTCCA ACAGCAACCA GCTACACCCC TAATTTGGCC
AGGGGCGACC CGGGCTTAGC CACCATTGCT AAAAGTGCAA CCATAGAACC TAAAGAGGTC
AAGCCCGAAA CAAAACCACC AGAACCCAAG AAAACCTTTA ACAGTGTCAG CAAAATTGAC
CGACTGTCAA GAATAGCCTT CCCGCTGCTA TTTGGAATCT TTAACTTAGT CTACTGGGCT
ACGTATTTAA ACAGAGAGCC TCAGCTAAAA GCCCCCACAC CACATCAATA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu26115
Clone ID Related Accession (Same CDS sequence) NM_000806 , NM_001127643 , NM_001127644 , NM_001127645 , NM_001127648
Accession Version NM_001127644.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1371bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product gamma-aminobutyric acid receptor subunit alpha-1 precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA075784.1, X14766.1, R60404.1, DA228536.1 and AC021079.4. Transcript Variant: This variant (3) differs in the 5' UTR, compared to variant 1. Variants 1-7 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: X14766.1, AK223447.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145743, SAMEA2154665 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
ATGAGGAAAA GTCCAGGTCT GTCTGACTGT CTTTGGGCCT GGATCCTCCT TCTGAGCACA 
CTGACTGGAA GAAGCTATGG ACAGCCGTCA TTACAAGATG AACTTAAAGA CAATACCACT
GTCTTCACCA GGATTTTGGA CAGACTCCTA GATGGTTATG ACAATCGCCT GAGACCAGGA
TTGGGAGAGC GTGTAACCGA AGTGAAGACT GATATCTTCG TCACCAGTTT CGGACCCGTT
TCAGACCATG ATATGGAATA TACAATAGAT GTATTTTTCC GTCAAAGCTG GAAGGATGAA
AGGTTAAAAT TTAAAGGACC TATGACAGTC CTCCGGTTAA ATAACCTAAT GGCAAGTAAA
ATCTGGACTC CGGACACATT TTTCCACAAT GGAAAGAAGT CAGTGGCCCA CAACATGACC
ATGCCCAACA AACTCCTGCG GATCACAGAG GATGGCACCT TGCTGTACAC CATGAGGCTG
ACAGTGAGAG CTGAATGTCC GATGCATTTG GAGGACTTCC CTATGGATGC CCATGCTTGC
CCACTAAAAT TTGGAAGTTA TGCTTATACA AGAGCAGAAG TTGTTTATGA ATGGACCAGA
GAGCCAGCAC GCTCAGTGGT TGTAGCAGAA GATGGATCAC GTCTAAACCA GTATGACCTT
CTTGGACAAA CAGTAGACTC TGGAATTGTC CAGTCAAGTA CAGGAGAATA TGTTGTTATG
ACCACTCATT TCCACTTGAA GAGAAAGATT GGCTACTTTG TTATTCAAAC ATACCTGCCA
TGCATAATGA CAGTGATTCT CTCACAAGTC TCCTTCTGGC TCAACAGAGA GTCTGTACCA
GCAAGAACTG TCTTTGGAGT AACAACTGTG CTCACCATGA CAACATTGAG CATCAGTGCC
AGAAACTCCC TCCCTAAGGT GGCTTATGCA ACAGCTATGG ATTGGTTTAT TGCCGTGTGC
TATGCCTTTG TGTTCTCAGC TCTGATTGAG TTTGCCACAG TAAACTATTT CACTAAGAGA
GGTTATGCAT GGGATGGCAA AAGTGTGGTT CCAGAAAAGC CAAAGAAAGT AAAGGATCCT
CTTATTAAGA AAAACAACAC TTACGCTCCA ACAGCAACCA GCTACACCCC TAATTTGGCC
AGGGGCGACC CGGGCTTAGC CACCATTGCT AAAAGTGCAA CCATAGAACC TAAAGAGGTC
AAGCCCGAAA CAAAACCACC AGAACCCAAG AAAACCTTTA ACAGTGTCAG CAAAATTGAC
CGACTGTCAA GAATAGCCTT CCCGCTGCTA TTTGGAATCT TTAACTTAGT CTACTGGGCT
ACGTATTTAA ACAGAGAGCC TCAGCTAAAA GCCCCCACAC CACATCAATA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001121116.1
CDS505..1875
Misc Feature(1)487..489(+)
Misc Feature(2)544..1830(+)
Misc Feature(3)631..1254(+)
Misc Feature(4)1258..1323(+)
Misc Feature(5)1273..1821(+)
Misc Feature(6)1339..1404(+)
Misc Feature(7)1441..1506(+)
Misc Feature(8)1768..1833(+)
Exon (1)1..489
Gene:GABRA1
Gene Synonym:
Exon (2)490..578
Gene:GABRA1
Gene Synonym:
Exon (3)579..691
Gene:GABRA1
Gene Synonym:
Exon (4)692..759
Gene:GABRA1
Gene Synonym:
Exon (5)760..980
Gene:GABRA1
Gene Synonym:
Exon (6)981..1063
Gene:GABRA1
Gene Synonym:
Exon (7)1064..1207
Gene:GABRA1
Gene Synonym:
Exon (8)1208..1360
Gene:GABRA1
Gene Synonym:
Exon (9)1361..1563
Gene:GABRA1
Gene Synonym:
Exon (10)1564..4412
Gene:GABRA1
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001127644
Organism Homo sapiens (human)
Definition Homo sapiens gamma-aminobutyric acid (GABA) A receptor, alpha 1 (GABRA1), transcript variant 3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001127644

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
ATGAGGAAAA GTCCAGGTCT GTCTGACTGT CTTTGGGCCT GGATCCTCCT TCTGAGCACA 
CTGACTGGAA GAAGCTATGG ACAGCCGTCA TTACAAGATG AACTTAAAGA CAATACCACT
GTCTTCACCA GGATTTTGGA CAGACTCCTA GATGGTTATG ACAATCGCCT GAGACCAGGA
TTGGGAGAGC GTGTAACCGA AGTGAAGACT GATATCTTCG TCACCAGTTT CGGACCCGTT
TCAGACCATG ATATGGAATA TACAATAGAT GTATTTTTCC GTCAAAGCTG GAAGGATGAA
AGGTTAAAAT TTAAAGGACC TATGACAGTC CTCCGGTTAA ATAACCTAAT GGCAAGTAAA
ATCTGGACTC CGGACACATT TTTCCACAAT GGAAAGAAGT CAGTGGCCCA CAACATGACC
ATGCCCAACA AACTCCTGCG GATCACAGAG GATGGCACCT TGCTGTACAC CATGAGGCTG
ACAGTGAGAG CTGAATGTCC GATGCATTTG GAGGACTTCC CTATGGATGC CCATGCTTGC
CCACTAAAAT TTGGAAGTTA TGCTTATACA AGAGCAGAAG TTGTTTATGA ATGGACCAGA
GAGCCAGCAC GCTCAGTGGT TGTAGCAGAA GATGGATCAC GTCTAAACCA GTATGACCTT
CTTGGACAAA CAGTAGACTC TGGAATTGTC CAGTCAAGTA CAGGAGAATA TGTTGTTATG
ACCACTCATT TCCACTTGAA GAGAAAGATT GGCTACTTTG TTATTCAAAC ATACCTGCCA
TGCATAATGA CAGTGATTCT CTCACAAGTC TCCTTCTGGC TCAACAGAGA GTCTGTACCA
GCAAGAACTG TCTTTGGAGT AACAACTGTG CTCACCATGA CAACATTGAG CATCAGTGCC
AGAAACTCCC TCCCTAAGGT GGCTTATGCA ACAGCTATGG ATTGGTTTAT TGCCGTGTGC
TATGCCTTTG TGTTCTCAGC TCTGATTGAG TTTGCCACAG TAAACTATTT CACTAAGAGA
GGTTATGCAT GGGATGGCAA AAGTGTGGTT CCAGAAAAGC CAAAGAAAGT AAAGGATCCT
CTTATTAAGA AAAACAACAC TTACGCTCCA ACAGCAACCA GCTACACCCC TAATTTGGCC
AGGGGCGACC CGGGCTTAGC CACCATTGCT AAAAGTGCAA CCATAGAACC TAAAGAGGTC
AAGCCCGAAA CAAAACCACC AGAACCCAAG AAAACCTTTA ACAGTGTCAG CAAAATTGAC
CGACTGTCAA GAATAGCCTT CCCGCTGCTA TTTGGAATCT TTAACTTAGT CTACTGGGCT
ACGTATTTAA ACAGAGAGCC TCAGCTAAAA GCCCCCACAC CACATCAATA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu26115
Clone ID Related Accession (Same CDS sequence) NM_000806 , NM_001127643 , NM_001127644 , NM_001127645 , NM_001127648
Accession Version NM_001127645.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1371bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product gamma-aminobutyric acid receptor subunit alpha-1 precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC307259.1, BC030696.1 and AC021079.4. Transcript Variant: This variant (4) differs in the 5' UTR, compared to variant 1. Variants 1-7 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC030696.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145743, SAMEA2154665 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
ATGAGGAAAA GTCCAGGTCT GTCTGACTGT CTTTGGGCCT GGATCCTCCT TCTGAGCACA 
CTGACTGGAA GAAGCTATGG ACAGCCGTCA TTACAAGATG AACTTAAAGA CAATACCACT
GTCTTCACCA GGATTTTGGA CAGACTCCTA GATGGTTATG ACAATCGCCT GAGACCAGGA
TTGGGAGAGC GTGTAACCGA AGTGAAGACT GATATCTTCG TCACCAGTTT CGGACCCGTT
TCAGACCATG ATATGGAATA TACAATAGAT GTATTTTTCC GTCAAAGCTG GAAGGATGAA
AGGTTAAAAT TTAAAGGACC TATGACAGTC CTCCGGTTAA ATAACCTAAT GGCAAGTAAA
ATCTGGACTC CGGACACATT TTTCCACAAT GGAAAGAAGT CAGTGGCCCA CAACATGACC
ATGCCCAACA AACTCCTGCG GATCACAGAG GATGGCACCT TGCTGTACAC CATGAGGCTG
ACAGTGAGAG CTGAATGTCC GATGCATTTG GAGGACTTCC CTATGGATGC CCATGCTTGC
CCACTAAAAT TTGGAAGTTA TGCTTATACA AGAGCAGAAG TTGTTTATGA ATGGACCAGA
GAGCCAGCAC GCTCAGTGGT TGTAGCAGAA GATGGATCAC GTCTAAACCA GTATGACCTT
CTTGGACAAA CAGTAGACTC TGGAATTGTC CAGTCAAGTA CAGGAGAATA TGTTGTTATG
ACCACTCATT TCCACTTGAA GAGAAAGATT GGCTACTTTG TTATTCAAAC ATACCTGCCA
TGCATAATGA CAGTGATTCT CTCACAAGTC TCCTTCTGGC TCAACAGAGA GTCTGTACCA
GCAAGAACTG TCTTTGGAGT AACAACTGTG CTCACCATGA CAACATTGAG CATCAGTGCC
AGAAACTCCC TCCCTAAGGT GGCTTATGCA ACAGCTATGG ATTGGTTTAT TGCCGTGTGC
TATGCCTTTG TGTTCTCAGC TCTGATTGAG TTTGCCACAG TAAACTATTT CACTAAGAGA
GGTTATGCAT GGGATGGCAA AAGTGTGGTT CCAGAAAAGC CAAAGAAAGT AAAGGATCCT
CTTATTAAGA AAAACAACAC TTACGCTCCA ACAGCAACCA GCTACACCCC TAATTTGGCC
AGGGGCGACC CGGGCTTAGC CACCATTGCT AAAAGTGCAA CCATAGAACC TAAAGAGGTC
AAGCCCGAAA CAAAACCACC AGAACCCAAG AAAACCTTTA ACAGTGTCAG CAAAATTGAC
CGACTGTCAA GAATAGCCTT CCCGCTGCTA TTTGGAATCT TTAACTTAGT CTACTGGGCT
ACGTATTTAA ACAGAGAGCC TCAGCTAAAA GCCCCCACAC CACATCAATA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001121117.1
CDS93..1463
Misc Feature(1)132..1418(+)
Misc Feature(2)219..842(+)
Misc Feature(3)846..911(+)
Misc Feature(4)861..1409(+)
Misc Feature(5)927..992(+)
Misc Feature(6)1029..1094(+)
Misc Feature(7)1356..1421(+)
Exon (1)1..77
Gene:GABRA1
Gene Synonym:
Exon (2)78..166
Gene:GABRA1
Gene Synonym:
Exon (3)167..279
Gene:GABRA1
Gene Synonym:
Exon (4)280..347
Gene:GABRA1
Gene Synonym:
Exon (5)348..568
Gene:GABRA1
Gene Synonym:
Exon (6)569..651
Gene:GABRA1
Gene Synonym:
Exon (7)652..795
Gene:GABRA1
Gene Synonym:
Exon (8)796..948
Gene:GABRA1
Gene Synonym:
Exon (9)949..1151
Gene:GABRA1
Gene Synonym:
Exon (10)1152..4000
Gene:GABRA1
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001127645
Organism Homo sapiens (human)
Definition Homo sapiens gamma-aminobutyric acid (GABA) A receptor, alpha 1 (GABRA1), transcript variant 4, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001127645

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
ATGAGGAAAA GTCCAGGTCT GTCTGACTGT CTTTGGGCCT GGATCCTCCT TCTGAGCACA 
CTGACTGGAA GAAGCTATGG ACAGCCGTCA TTACAAGATG AACTTAAAGA CAATACCACT
GTCTTCACCA GGATTTTGGA CAGACTCCTA GATGGTTATG ACAATCGCCT GAGACCAGGA
TTGGGAGAGC GTGTAACCGA AGTGAAGACT GATATCTTCG TCACCAGTTT CGGACCCGTT
TCAGACCATG ATATGGAATA TACAATAGAT GTATTTTTCC GTCAAAGCTG GAAGGATGAA
AGGTTAAAAT TTAAAGGACC TATGACAGTC CTCCGGTTAA ATAACCTAAT GGCAAGTAAA
ATCTGGACTC CGGACACATT TTTCCACAAT GGAAAGAAGT CAGTGGCCCA CAACATGACC
ATGCCCAACA AACTCCTGCG GATCACAGAG GATGGCACCT TGCTGTACAC CATGAGGCTG
ACAGTGAGAG CTGAATGTCC GATGCATTTG GAGGACTTCC CTATGGATGC CCATGCTTGC
CCACTAAAAT TTGGAAGTTA TGCTTATACA AGAGCAGAAG TTGTTTATGA ATGGACCAGA
GAGCCAGCAC GCTCAGTGGT TGTAGCAGAA GATGGATCAC GTCTAAACCA GTATGACCTT
CTTGGACAAA CAGTAGACTC TGGAATTGTC CAGTCAAGTA CAGGAGAATA TGTTGTTATG
ACCACTCATT TCCACTTGAA GAGAAAGATT GGCTACTTTG TTATTCAAAC ATACCTGCCA
TGCATAATGA CAGTGATTCT CTCACAAGTC TCCTTCTGGC TCAACAGAGA GTCTGTACCA
GCAAGAACTG TCTTTGGAGT AACAACTGTG CTCACCATGA CAACATTGAG CATCAGTGCC
AGAAACTCCC TCCCTAAGGT GGCTTATGCA ACAGCTATGG ATTGGTTTAT TGCCGTGTGC
TATGCCTTTG TGTTCTCAGC TCTGATTGAG TTTGCCACAG TAAACTATTT CACTAAGAGA
GGTTATGCAT GGGATGGCAA AAGTGTGGTT CCAGAAAAGC CAAAGAAAGT AAAGGATCCT
CTTATTAAGA AAAACAACAC TTACGCTCCA ACAGCAACCA GCTACACCCC TAATTTGGCC
AGGGGCGACC CGGGCTTAGC CACCATTGCT AAAAGTGCAA CCATAGAACC TAAAGAGGTC
AAGCCCGAAA CAAAACCACC AGAACCCAAG AAAACCTTTA ACAGTGTCAG CAAAATTGAC
CGACTGTCAA GAATAGCCTT CCCGCTGCTA TTTGGAATCT TTAACTTAGT CTACTGGGCT
ACGTATTTAA ACAGAGAGCC TCAGCTAAAA GCCCCCACAC CACATCAATA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu26115
Clone ID Related Accession (Same CDS sequence) NM_000806 , NM_001127643 , NM_001127644 , NM_001127645 , NM_001127648
Accession Version NM_001127648.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1371bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product gamma-aminobutyric acid receptor subunit alpha-1 precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC334834.1, DA232066.1, X14766.1 and AC021079.4. Transcript Variant: This variant (7) differs in the 5' UTR, compared to variant 1. Variants 1-7 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: BC030696.1, AK289792.1 [ECO:0000331] RNAseq introns :: single sample supports all introns SAMEA2142586, SAMEA2145743 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
ATGAGGAAAA GTCCAGGTCT GTCTGACTGT CTTTGGGCCT GGATCCTCCT TCTGAGCACA 
CTGACTGGAA GAAGCTATGG ACAGCCGTCA TTACAAGATG AACTTAAAGA CAATACCACT
GTCTTCACCA GGATTTTGGA CAGACTCCTA GATGGTTATG ACAATCGCCT GAGACCAGGA
TTGGGAGAGC GTGTAACCGA AGTGAAGACT GATATCTTCG TCACCAGTTT CGGACCCGTT
TCAGACCATG ATATGGAATA TACAATAGAT GTATTTTTCC GTCAAAGCTG GAAGGATGAA
AGGTTAAAAT TTAAAGGACC TATGACAGTC CTCCGGTTAA ATAACCTAAT GGCAAGTAAA
ATCTGGACTC CGGACACATT TTTCCACAAT GGAAAGAAGT CAGTGGCCCA CAACATGACC
ATGCCCAACA AACTCCTGCG GATCACAGAG GATGGCACCT TGCTGTACAC CATGAGGCTG
ACAGTGAGAG CTGAATGTCC GATGCATTTG GAGGACTTCC CTATGGATGC CCATGCTTGC
CCACTAAAAT TTGGAAGTTA TGCTTATACA AGAGCAGAAG TTGTTTATGA ATGGACCAGA
GAGCCAGCAC GCTCAGTGGT TGTAGCAGAA GATGGATCAC GTCTAAACCA GTATGACCTT
CTTGGACAAA CAGTAGACTC TGGAATTGTC CAGTCAAGTA CAGGAGAATA TGTTGTTATG
ACCACTCATT TCCACTTGAA GAGAAAGATT GGCTACTTTG TTATTCAAAC ATACCTGCCA
TGCATAATGA CAGTGATTCT CTCACAAGTC TCCTTCTGGC TCAACAGAGA GTCTGTACCA
GCAAGAACTG TCTTTGGAGT AACAACTGTG CTCACCATGA CAACATTGAG CATCAGTGCC
AGAAACTCCC TCCCTAAGGT GGCTTATGCA ACAGCTATGG ATTGGTTTAT TGCCGTGTGC
TATGCCTTTG TGTTCTCAGC TCTGATTGAG TTTGCCACAG TAAACTATTT CACTAAGAGA
GGTTATGCAT GGGATGGCAA AAGTGTGGTT CCAGAAAAGC CAAAGAAAGT AAAGGATCCT
CTTATTAAGA AAAACAACAC TTACGCTCCA ACAGCAACCA GCTACACCCC TAATTTGGCC
AGGGGCGACC CGGGCTTAGC CACCATTGCT AAAAGTGCAA CCATAGAACC TAAAGAGGTC
AAGCCCGAAA CAAAACCACC AGAACCCAAG AAAACCTTTA ACAGTGTCAG CAAAATTGAC
CGACTGTCAA GAATAGCCTT CCCGCTGCTA TTTGGAATCT TTAACTTAGT CTACTGGGCT
ACGTATTTAA ACAGAGAGCC TCAGCTAAAA GCCCCCACAC CACATCAATA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001121120.1
CDS115..1485
Misc Feature(1)52..54(+)
Misc Feature(2)154..1440(+)
Misc Feature(3)241..864(+)
Misc Feature(4)868..933(+)
Misc Feature(5)883..1431(+)
Misc Feature(6)949..1014(+)
Misc Feature(7)1051..1116(+)
Misc Feature(8)1378..1443(+)
Exon (1)1..188
Gene:GABRA1
Gene Synonym:
Exon (2)189..301
Gene:GABRA1
Gene Synonym:
Exon (3)302..369
Gene:GABRA1
Gene Synonym:
Exon (4)370..590
Gene:GABRA1
Gene Synonym:
Exon (5)591..673
Gene:GABRA1
Gene Synonym:
Exon (6)674..817
Gene:GABRA1
Gene Synonym:
Exon (7)818..970
Gene:GABRA1
Gene Synonym:
Exon (8)971..1173
Gene:GABRA1
Gene Synonym:
Exon (9)1174..4022
Gene:GABRA1
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001127648
Organism Homo sapiens (human)
Definition Homo sapiens gamma-aminobutyric acid (GABA) A receptor, alpha 1 (GABRA1), transcript variant 7, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001127648

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
ATGAGGAAAA GTCCAGGTCT GTCTGACTGT CTTTGGGCCT GGATCCTCCT TCTGAGCACA 
CTGACTGGAA GAAGCTATGG ACAGCCGTCA TTACAAGATG AACTTAAAGA CAATACCACT
GTCTTCACCA GGATTTTGGA CAGACTCCTA GATGGTTATG ACAATCGCCT GAGACCAGGA
TTGGGAGAGC GTGTAACCGA AGTGAAGACT GATATCTTCG TCACCAGTTT CGGACCCGTT
TCAGACCATG ATATGGAATA TACAATAGAT GTATTTTTCC GTCAAAGCTG GAAGGATGAA
AGGTTAAAAT TTAAAGGACC TATGACAGTC CTCCGGTTAA ATAACCTAAT GGCAAGTAAA
ATCTGGACTC CGGACACATT TTTCCACAAT GGAAAGAAGT CAGTGGCCCA CAACATGACC
ATGCCCAACA AACTCCTGCG GATCACAGAG GATGGCACCT TGCTGTACAC CATGAGGCTG
ACAGTGAGAG CTGAATGTCC GATGCATTTG GAGGACTTCC CTATGGATGC CCATGCTTGC
CCACTAAAAT TTGGAAGTTA TGCTTATACA AGAGCAGAAG TTGTTTATGA ATGGACCAGA
GAGCCAGCAC GCTCAGTGGT TGTAGCAGAA GATGGATCAC GTCTAAACCA GTATGACCTT
CTTGGACAAA CAGTAGACTC TGGAATTGTC CAGTCAAGTA CAGGAGAATA TGTTGTTATG
ACCACTCATT TCCACTTGAA GAGAAAGATT GGCTACTTTG TTATTCAAAC ATACCTGCCA
TGCATAATGA CAGTGATTCT CTCACAAGTC TCCTTCTGGC TCAACAGAGA GTCTGTACCA
GCAAGAACTG TCTTTGGAGT AACAACTGTG CTCACCATGA CAACATTGAG CATCAGTGCC
AGAAACTCCC TCCCTAAGGT GGCTTATGCA ACAGCTATGG ATTGGTTTAT TGCCGTGTGC
TATGCCTTTG TGTTCTCAGC TCTGATTGAG TTTGCCACAG TAAACTATTT CACTAAGAGA
GGTTATGCAT GGGATGGCAA AAGTGTGGTT CCAGAAAAGC CAAAGAAAGT AAAGGATCCT
CTTATTAAGA AAAACAACAC TTACGCTCCA ACAGCAACCA GCTACACCCC TAATTTGGCC
AGGGGCGACC CGGGCTTAGC CACCATTGCT AAAAGTGCAA CCATAGAACC TAAAGAGGTC
AAGCCCGAAA CAAAACCACC AGAACCCAAG AAAACCTTTA ACAGTGTCAG CAAAATTGAC
CGACTGTCAA GAATAGCCTT CCCGCTGCTA TTTGGAATCT TTAACTTAGT CTACTGGGCT
ACGTATTTAA ACAGAGAGCC TCAGCTAAAA GCCCCCACAC CACATCAATA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

GABRA1 and STXBP1: novel genetic causes of Dravet syndrome
Neurology 82 (14), 1245-1253 (2014)
Carvill GL, Weckhuysen S, McMahon JM, Hartmann C, Moller RS, Hjalgrim H, Cook J, Geraghty E, O'Roak BJ, Petrou S, Clarke A, Gill D, Sadleir LG, Muhle H, von Spiczak S, Nikanorova M, Hodgson BL, Gazina EV, Suls A, Shendure J, Dibbens LM, De Jonghe P, Helbig I, Berkovic SF, Scheffer IE and Mefford HC.


book

Specificity of intersubunit general anesthetic-binding sites in the transmembrane domain of the human alpha1beta3gamma2 gamma-aminobutyric acid type A (GABAA) receptor
J. Biol. Chem. 288 (27), 19343-19357 (2013)
Chiara DC, Jayakar SS, Zhou X, Zhang X, Savechenkov PY, Bruzik KS, Miller KW and Cohen JB.


book

The quest for juvenile myoclonic epilepsy genes
Epilepsy Behav 28 (SUPPL 1), S52-S57 (2013)
Delgado-Escueta AV, Koeleman BP, Bailey JN, Medina MT and Duron RM.


book

Association between GABA(A) receptor subunit gene cluster and zolpidem-induced complex sleep behaviors in Han Chinese
Sleep 36 (2), 197-202 (2013)
Tsai JH, Yang P, Lin HH, Cheng KH, Yang YH, Wu MT and Chen CC.


book

A unified model of the GABA(A) receptor comprising agonist and benzodiazepine binding sites
PLoS ONE 8 (1), E52323 (2013)
Bergmann R, Kongsbak K, Sorensen PL, Sander T and Balle T.


book

gamma-Aminobutyric acidA receptors displaying association of gamma 3-subunits with beta 2/3 and different alpha-subunits exhibit unique pharmacological properties
J. Biol. Chem. 269 (17), 12993-12998 (1994)
Togel M, Mossier B, Fuchs K and Sieghart W.


book

Isolation and characterization of the promoter of the human GABAA receptor alpha 1 subunit gene
J. Neurochem. 62 (4), 1643-1646 (1994)
Kang I, Lindquist DG, Kinane TB, Ercolani L, Pritchard GA and Miller LG.


book

Confirmation of the localization of the human GABAA receptor alpha 1-subunit gene (GABRA1) to distal 5q by linkage analysis
Genomics 14 (3), 745-748 (1992)
Johnson KJ, Sander T, Hicks AA, van Marle A, Janz D, Mullan MJ, Riley BP and Darlison MG.


book

Sequence and expression of human GABAA receptor alpha 1 and beta 1 subunits
FEBS Lett. 244 (2), 361-364 (1989)
Schofield PR, Pritchett DB, Sontheimer H, Kettenmann H and Seeburg PH.


book

Isolation of a cDNA clone for the alpha subunit of the human GABA-A receptor
Biochem. Biophys. Res. Commun. 156 (2), 1039-1045 (1988)
Garrett KM, Duman RS, Saito N, Blume AJ, Vitek MP and Tallman JF.


 
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