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GABRB1 cDNA ORF clone, Homo sapiens (human)

Gene Symbol GABRB1
Entrez Gene ID 2560
Full Name gamma-aminobutyric acid (GABA) A receptor, beta 1
General protein information
Preferred Names
gamma-aminobutyric acid receptor subunit beta-1
Names
gamma-aminobutyric acid receptor subunit beta-1
GABA(A) receptor, beta 1
GABA(A) receptor subunit beta-1
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

4

4p12

Summary The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, beta 1 subunit. It is mapped to chromosome 4p12 in a cluster comprised of genes encoding alpha 4, alpha 2 and gamma 1 subunits of the GABA A receptor. Alteration of this gene is implicated in the pathogenetics of schizophrenia. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

137190


mRNA and Protein(s)

mRNA Protein Name
XM_011513678 XP_011511980 gamma-aminobutyric acid receptor subunit beta-1 isoform X1
NM_000812 NP_000803 gamma-aminobutyric acid receptor subunit beta-1 precursor



Homo sapiens (human) GABRB1 NP_000803.2
Pan troglodytes (chimpanzee) GABRB1 XP_001154620.1
Macaca mulatta (Rhesus monkey) GABRB1 XP_002804095.1
Canis lupus familiaris (dog) GABRB1 XP_005628215.1
Bos taurus (cattle) GABRB1 NP_776969.1
Mus musculus (house mouse) Gabrb1 NP_032095.1
Rattus norvegicus (Norway rat) Gabrb1 NP_037088.1
Gallus gallus (chicken) GABRQ NP_001161175.1
Danio rerio (zebrafish) gabrb1 XP_002664179.2
Xenopus (Silurana) tropicalis (western clawed frog) gabrb1 XP_004911268.1


GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following GABRB1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GABRB1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu57887 XM_011513678 PREDICTED: Homo sapiens gamma-aminobutyric acid (GABA) A receptor, beta 1 (GABRB1), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $223.30
$319.00
OHu17601 NM_000812 Homo sapiens gamma-aminobutyric acid (GABA) A receptor, beta 1 (GABRB1), mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $265.30
$379.00
Next-day Shipping ORF Clones ( in default vector with tag)
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2-4 Clone 40% OFF
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu57887
Clone ID Related Accession (Same CDS sequence) XM_011513678
Accession Version XM_011513678.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1404bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product gamma-aminobutyric acid receptor subunit beta-1 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_006238.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGAAGCTCC TCTGTCATCA GAATGGAGTT GACTTACTTC CAGAGGTTGA CTGCTTTAGC 
ACCAATGAAC CCAGCAACAT GTCATACGTG AAAGAGACAG TGGACAGATT GCTCAAAGGA
TATGACATTC GCTTGCGGCC GGACTTCGGA GGGCCCCCCG TCGACGTTGG GATGCGGATC
GATGTCGCCA GCATAGACAT GGTCTCCGAA GTGAATATGG ATTATACACT CACCATGTAT
TTCCAGCAGT CTTGGAAAGA CAAAAGGCTT TCTTATTCTG GAATCCCACT GAACCTCACC
CTAGACAATA GGGTAGCTGA CCAACTCTGG GTACCAGACA CCTACTTTCT GAATGACAAG
AAATCATTTG TGCATGGGGT CACAGTGAAA AATCGAATGA TTCGACTGCA TCCTGATGGA
ACAGTTCTCT ATGGACTCCG AATCACAACC ACAGCTGCAT GTATGATGGA TCTTCGAAGA
TATCCATTGG ATGAGCAGAA CTGCACCCTG GAGATCGAAA GTTATGGCTA TACCACTGAT
GACATTGAAT TTTACTGGAA TGGAGGAGAA GGGGCAGTCA CTGGTGTTAA TAAAATCGAA
CTTCCTCAAT TTTCAATTGT TGACTACAAG ATGGTGTCTA AGAAGGTGGA GTTCACAACA
GGAGCGTATC CACGACTGTC ACTAAGTTTT CGTCTAAAGA GAAACATTGG TTACTTCATT
TTGCAAACCT ACATGCCTTC TACACTGATT ACAATTCTGT CCTGGGTGTC TTTTTGGATC
AACTATGATG CATCTGCAGC CAGAGTCGCA CTAGGAATCA CGACAGTGCT TACAATGACA
ACCATCAGCA CCCACCTCAG GGAGACCCTG CCAAAGATCC CTTATGTCAA AGCGATTGAT
ATTTATCTGA TGGGTTGCTT TGTGTTTGTG TTCCTGGCTC TGCTGGAGTA TGCCTTTGTA
AATTACATCT TCTTTGGGAA AGGCCCTCAG AAAAAGGGAG CTAGCAAACA AGACCAGAGT
GCCAATGAGA AGAATAAACT GGAGATGAAT AAAGTCCAGG TCGACGCCCA CGGTAACATT
CTCCTCAGCA CCCTGGAAAT CCGGAATGAG ACGAGTGGCT CGGAAGTGCT CACGAGCGTG
AGCGACCCCA AGGCCACCAT GTACTCCTAT GACAGCGCCA GCATCCAGTA CCGCAAGCCC
CTGAGCAGCC GCGAGGCCTA CGGGCGCGCC CTGGACCGGC ACGGGGTACC CAGCAAGGGG
CGCATCCGCA GGCGTGCCTC CCAGCTCAAA GTCAAGATCC CCGACTTGAC TGATGTGAAT
TCCATAGACA AGTGGTCCCG AATGTTTTTC CCCATCACCT TTTCTCTTTT TAATGTCGTC
TATTGGCTTT ACTATGTACA CTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011511980.1
CDS49..1452
Misc Feature(1)106..1443(+)
Misc Feature(2)148..756(+)
Misc Feature(3)775..1434(+)
Translation

Target ORF information:

RefSeq Version XM_011513678
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens gamma-aminobutyric acid (GABA) A receptor, beta 1 (GABRB1), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011513678

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGAAGCTCC TCTGTCATCA GAATGGAGTT GACTTACTTC CAGAGGTTGA CTGCTTTAGC 
ACCAATGAAC CCAGCAACAT GTCATACGTG AAAGAGACAG TGGACAGATT GCTCAAAGGA
TATGACATTC GCTTGCGGCC GGACTTCGGA GGGCCCCCCG TCGACGTTGG GATGCGGATC
GATGTCGCCA GCATAGACAT GGTCTCCGAA GTGAATATGG ATTATACACT CACCATGTAT
TTCCAGCAGT CTTGGAAAGA CAAAAGGCTT TCTTATTCTG GAATCCCACT GAACCTCACC
CTAGACAATA GGGTAGCTGA CCAACTCTGG GTACCAGACA CCTACTTTCT GAATGACAAG
AAATCATTTG TGCATGGGGT CACAGTGAAA AATCGAATGA TTCGACTGCA TCCTGATGGA
ACAGTTCTCT ATGGACTCCG AATCACAACC ACAGCTGCAT GTATGATGGA TCTTCGAAGA
TATCCATTGG ATGAGCAGAA CTGCACCCTG GAGATCGAAA GTTATGGCTA TACCACTGAT
GACATTGAAT TTTACTGGAA TGGAGGAGAA GGGGCAGTCA CTGGTGTTAA TAAAATCGAA
CTTCCTCAAT TTTCAATTGT TGACTACAAG ATGGTGTCTA AGAAGGTGGA GTTCACAACA
GGAGCGTATC CACGACTGTC ACTAAGTTTT CGTCTAAAGA GAAACATTGG TTACTTCATT
TTGCAAACCT ACATGCCTTC TACACTGATT ACAATTCTGT CCTGGGTGTC TTTTTGGATC
AACTATGATG CATCTGCAGC CAGAGTCGCA CTAGGAATCA CGACAGTGCT TACAATGACA
ACCATCAGCA CCCACCTCAG GGAGACCCTG CCAAAGATCC CTTATGTCAA AGCGATTGAT
ATTTATCTGA TGGGTTGCTT TGTGTTTGTG TTCCTGGCTC TGCTGGAGTA TGCCTTTGTA
AATTACATCT TCTTTGGGAA AGGCCCTCAG AAAAAGGGAG CTAGCAAACA AGACCAGAGT
GCCAATGAGA AGAATAAACT GGAGATGAAT AAAGTCCAGG TCGACGCCCA CGGTAACATT
CTCCTCAGCA CCCTGGAAAT CCGGAATGAG ACGAGTGGCT CGGAAGTGCT CACGAGCGTG
AGCGACCCCA AGGCCACCAT GTACTCCTAT GACAGCGCCA GCATCCAGTA CCGCAAGCCC
CTGAGCAGCC GCGAGGCCTA CGGGCGCGCC CTGGACCGGC ACGGGGTACC CAGCAAGGGG
CGCATCCGCA GGCGTGCCTC CCAGCTCAAA GTCAAGATCC CCGACTTGAC TGATGTGAAT
TCCATAGACA AGTGGTCCCG AATGTTTTTC CCCATCACCT TTTCTCTTTT TAATGTCGTC
TATTGGCTTT ACTATGTACA CTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu17601
Clone ID Related Accession (Same CDS sequence) NM_000812
Accession Version NM_000812.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1425bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product gamma-aminobutyric acid receptor subunit beta-1 precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC352362.1, AK225167.1, X14767.1 and AK225686.1. On Jul 11, 2008 this sequence version replaced gi:12548775. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC022449.1, X14767.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145743, SAMEA2151741 [ECO:0000348] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGTGGACAG TACAAAATCG AGAGAGTCTG GGGCTTCTCT CTTTCCCTGT GATGATTACC 
ATGGTCTGTT GTGCACACAG CACCAATGAA CCCAGCAACA TGTCATACGT GAAAGAGACA
GTGGACAGAT TGCTCAAAGG ATATGACATT CGCTTGCGGC CGGACTTCGG AGGGCCCCCC
GTCGACGTTG GGATGCGGAT CGATGTCGCC AGCATAGACA TGGTCTCCGA AGTGAATATG
GATTATACAC TCACCATGTA TTTCCAGCAG TCTTGGAAAG ACAAAAGGCT TTCTTATTCT
GGAATCCCAC TGAACCTCAC CCTAGACAAT AGGGTAGCTG ACCAACTCTG GGTACCAGAC
ACCTACTTTC TGAATGACAA GAAATCATTT GTGCATGGGG TCACAGTGAA AAATCGAATG
ATTCGACTGC ATCCTGATGG AACAGTTCTC TATGGACTCC GAATCACAAC CACAGCTGCA
TGTATGATGG ATCTTCGAAG ATATCCACTG GATGAGCAGA ACTGCACCCT GGAGATCGAA
AGTTATGGCT ATACCACTGA TGACATTGAA TTTTACTGGA ATGGAGGAGA AGGGGCAGTC
ACTGGTGTTA ATAAAATCGA ACTTCCTCAA TTTTCAATTG TTGACTACAA GATGGTGTCT
AAGAAGGTGG AGTTCACAAC AGGAGCGTAT CCACGACTGT CACTAAGTTT TCGTCTAAAG
AGAAACATTG GTTACTTCAT TTTGCAAACC TACATGCCTT CTACACTGAT TACAATTCTG
TCCTGGGTGT CTTTTTGGAT CAACTATGAT GCATCTGCAG CCAGAGTCGC ACTAGGAATC
ACGACAGTGC TTACAATGAC AACCATCAGC ACCCACCTCA GGGAGACCCT GCCAAAGATC
CCTTATGTCA AAGCGATTGA TATTTATCTG ATGGGTTGCT TTGTGTTTGT GTTCCTGGCT
CTGCTGGAGT ATGCCTTTGT AAATTACATC TTCTTTGGGA AAGGCCCTCA GAAAAAGGGA
GCTAGCAAAC AAGACCAGAG TGCCAATGAG AAGAATAAAC TGGAGATGAA TAAAGTCCAG
GTCGACGCCC ACGGTAACAT TCTCCTCAGC ACCCTGGAAA TCCGGAATGA GACGAGTGGC
TCGGAAGTGC TCACGAGCGT GAGCGACCCC AAGGCCACCA TGTACTCCTA TGACAGCGCC
AGCATCCAGT ACCGCAAGCC CCTGAGCAGC CGCGAGGCCT ACGGGCGCGC CCTGGACCGG
CACGGGGTAC CCAGCAAGGG GCGCATCCGC AGGCGTGCCT CCCAGCTCAA AGTCAAGATC
CCCGACTTGA CTGATGTGAA TTCCATAGAC AAGTGGTCCC GAATGTTTTT CCCCATCACC
TTTTCTCTTT TTAATGTCGT CTATTGGCTT TACTATGTAC ACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_000803.2
CDS375..1799
Misc Feature(1)360..362(+)
Misc Feature(2)399..1790(+)
Misc Feature(3)495..1103(+)
Misc Feature(4)1110..1175(+)
Misc Feature(5)1122..1781(+)
Misc Feature(6)1185..1253(+)
Misc Feature(7)1287..1355(+)
Misc Feature(8)1728..1793(+)
Exon (1)1..454
Gene:GABRB1
Gene Synonym:
Exon (2)455..546
Gene:GABRB1
Gene Synonym:
Exon (3)547..614
Gene:GABRB1
Gene Synonym:
Exon (4)615..835
Gene:GABRB1
Gene Synonym:
Exon (5)836..918
Gene:GABRB1
Gene Synonym:
Exon (6)919..1056
Gene:GABRB1
Gene Synonym:
Exon (7)1057..1209
Gene:GABRB1
Gene Synonym:
Exon (8)1210..1454
Gene:GABRB1
Gene Synonym:
Exon (9)1455..2226
Gene:GABRB1
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_000812
Organism Homo sapiens (human)
Definition Homo sapiens gamma-aminobutyric acid (GABA) A receptor, beta 1 (GABRB1), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_000812

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGTGGACAG TACAAAATCG AGAGAGTCTG GGGCTTCTCT CTTTCCCTGT GATGATTACC 
ATGGTCTGTT GTGCACACAG CACCAATGAA CCCAGCAACA TGTCATACGT GAAAGAGACA
GTGGACAGAT TGCTCAAAGG ATATGACATT CGCTTGCGGC CGGACTTCGG AGGGCCCCCC
GTCGACGTTG GGATGCGGAT CGATGTCGCC AGCATAGACA TGGTCTCCGA AGTGAATATG
GATTATACAC TCACCATGTA TTTCCAGCAG TCTTGGAAAG ACAAAAGGCT TTCTTATTCT
GGAATCCCAC TGAACCTCAC CCTAGACAAT AGGGTAGCTG ACCAACTCTG GGTACCAGAC
ACCTACTTTC TGAATGACAA GAAATCATTT GTGCATGGGG TCACAGTGAA AAATCGAATG
ATTCGACTGC ATCCTGATGG AACAGTTCTC TATGGACTCC GAATCACAAC CACAGCTGCA
TGTATGATGG ATCTTCGAAG ATATCCACTG GATGAGCAGA ACTGCACCCT GGAGATCGAA
AGTTATGGCT ATACCACTGA TGACATTGAA TTTTACTGGA ATGGAGGAGA AGGGGCAGTC
ACTGGTGTTA ATAAAATCGA ACTTCCTCAA TTTTCAATTG TTGACTACAA GATGGTGTCT
AAGAAGGTGG AGTTCACAAC AGGAGCGTAT CCACGACTGT CACTAAGTTT TCGTCTAAAG
AGAAACATTG GTTACTTCAT TTTGCAAACC TACATGCCTT CTACACTGAT TACAATTCTG
TCCTGGGTGT CTTTTTGGAT CAACTATGAT GCATCTGCAG CCAGAGTCGC ACTAGGAATC
ACGACAGTGC TTACAATGAC AACCATCAGC ACCCACCTCA GGGAGACCCT GCCAAAGATC
CCTTATGTCA AAGCGATTGA TATTTATCTG ATGGGTTGCT TTGTGTTTGT GTTCCTGGCT
CTGCTGGAGT ATGCCTTTGT AAATTACATC TTCTTTGGGA AAGGCCCTCA GAAAAAGGGA
GCTAGCAAAC AAGACCAGAG TGCCAATGAG AAGAATAAAC TGGAGATGAA TAAAGTCCAG
GTCGACGCCC ACGGTAACAT TCTCCTCAGC ACCCTGGAAA TCCGGAATGA GACGAGTGGC
TCGGAAGTGC TCACGAGCGT GAGCGACCCC AAGGCCACCA TGTACTCCTA TGACAGCGCC
AGCATCCAGT ACCGCAAGCC CCTGAGCAGC CGCGAGGCCT ACGGGCGCGC CCTGGACCGG
CACGGGGTAC CCAGCAAGGG GCGCATCCGC AGGCGTGCCT CCCAGCTCAA AGTCAAGATC
CCCGACTTGA CTGATGTGAA TTCCATAGAC AAGTGGTCCC GAATGTTTTT CCCCATCACC
TTTTCTCTTT TTAATGTCGT CTATTGGCTT TACTATGTAC ACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

 
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