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GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2 [Homo sapiens (human)]

Gene Symbol GABRG2
Entrez Gene ID 2566
Full Name gamma-aminobutyric acid (GABA) A receptor, gamma 2
Synonyms CAE2, ECA2, GEFSP3
General protein information
Preferred Names
gamma-aminobutyric acid receptor subunit gamma-2
Names
gamma-aminobutyric acid receptor subunit gamma-2
GABA(A) receptor, gamma 2
GABA(A) receptor subunit gamma-2
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

5

5q34

Summary This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammlian brain, where it acts at GABA-A receptors, which are ligand-gated chloride channels. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene have been associated with epilepsy and febrile seizures. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

137164

Disorder Html: Epilepsy, generalized, with febrile seizures plus, type 3, 604233





The following GABRG2 gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GABRG2 gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu17585 NM_000816 Homo sapiens gamma-aminobutyric acid (GABA) A receptor, gamma 2 (GABRG2), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $389
OHu17503 NM_198904 Homo sapiens gamma-aminobutyric acid (GABA) A receptor, gamma 2 (GABRG2), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector in pcDNA3.1+/C-(K)DYK $379
OHu18155 NM_198903 Homo sapiens gamma-aminobutyric acid (GABA) A receptor, gamma 2 (GABRG2), transcript variant 3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $429

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu17585
Accession Version NM_000816.3
Sequence Information ORF Nucleotide Sequence (Length: 1404bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product gamma-aminobutyric acid receptor subunit gamma-2 isoform 2 precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA226729.1, BC074795.2, BC069348.1 and AC091984.3. On May 24, 2008 this sequence version replaced gi:38788134. Summary: This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammlian brain, where it acts at GABA-A receptors, which are ligand-gated chloride channels. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene have been associated with epilepsy and febrile seizures. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]. Transcript Variant: This variant (2) lacks two alternate in-frame exons, compared to variant 3. It encodes isoform 2 which is shorter than isoform 3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: X15376.1, BC069348.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2145544 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGAGTTCGC CAAATATATG GAGCACAGGA AGCTCAGTCT ACTCGACTCC TGTATTTTCA 
CAGAAAATGA CGGTGTGGAT TCTGCTCCTG CTGTCGCTCT ACCCTGGCTT CACTAGCCAG
AAATCTGATG ATGACTATGA AGATTATGCT TCTAACAAAA CATGGGTCTT GACTCCAAAA
GTTCCTGAGG GTGATGTCAC TGTCATCTTA AACAACCTGC TGGAAGGATA TGACAATAAA
CTTCGGCCTG ATATAGGAGT GAAGCCAACG TTAATTCACA CAGACATGTA TGTGAATAGC
ATTGGTCCAG TGAACGCTAT CAATATGGAA TACACTATTG ATATATTTTT TGCGCAAACG
TGGTATGACA GACGTTTGAA ATTTAACAGC ACCATTAAAG TCCTCCGATT GAACAGCAAC
ATGGTGGGGA AAATCTGGAT TCCAGACACT TTCTTCAGAA ATTCCAAAAA AGCTGATGCA
CACTGGATCA CCACCCCCAA CAGGATGCTG AGAATTTGGA ATGATGGTCG AGTGCTCTAC
ACCCTAAGGT TGACAATTGA TGCTGAGTGC CAATTACAAT TGCACAACTT TCCAATGGAT
GAACACTCCT GCCCCTTGGA GTTCTCCAGT TATGGCTATC CACGTGAAGA AATTGTTTAT
CAATGGAAGC GAAGTTCTGT TGAAGTGGGC GACACAAGAT CCTGGAGGCT TTATCAATTC
TCATTTGTTG GTCTAAGAAA TACCACCGAA GTAGTGAAGA CAACTTCCGG AGATTATGTG
GTCATGTCTG TCTACTTTGA TCTGAGCAGA AGAATGGGAT ACTTTACCAT CCAGACCTAT
ATCCCCTGCA CACTCATTGT CGTCCTATCC TGGGTGTCTT TCTGGATCAA TAAGGATGCT
GTTCCAGCCA GAACATCTTT AGGTATCACC ACTGTCCTGA CAATGACCAC CCTCAGCACC
ATTGCCCGGA AATCGCTCCC CAAGGTCTCC TATGTCACAG CGATGGATCT CTTTGTATCT
GTTTGTTTCA TCTTTGTCTT CTCTGCTCTG GTGGAGTATG GCACCTTGCA TTATTTTGTC
AGCAACCGGA AACCAAGCAA GGACAAAGAT AAAAAGAAGA AAAACCCTGC CCCTACCATT
GATATCCGCC CAAGATCAGC AACCATTCAA ATGAATAATG CTACACACCT TCAAGAGAGA
GATGAAGAGT ACGGCTATGA GTGTCTGGAC GGCAAGGACT GTGCCAGTTT TTTCTGCTGT
TTTGAAGATT GTCGAACAGG AGCTTGGAGA CATGGGAGGA TACATATCCG CATTGCCAAA
ATGGACTCCT ATGCTCGGAT CTTCTTCCCC ACTGCCTTCT GCCTGTTTAA TCTGGTCTAT
TGGGTCTCCT ACCTCTACCT GTGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_000807.2
CDS359..1762
Misc Feature(1)290..292(+)
Misc Feature(2)563..1750(+)
Misc Feature(3)563..1174(+)
Misc Feature(4)1178..1246(+)
Misc Feature(5)1193..1741(+)
Misc Feature(6)1256..1324(+)
Misc Feature(7)1358..1426(+)
Misc Feature(8)1454..1456(+)
Misc Feature(9)1631..1684(+)
Misc Feature(10)1688..1756(+)
Exon (1)1..465
Gene:GABRG2
Gene Synonym:
Exon (2)466..617
Gene:GABRG2
Gene Synonym:
Exon (3)618..685
Gene:GABRG2
Gene Synonym:
Exon (4)686..906
Gene:GABRG2
Gene Synonym:
Exon (5)907..989
Gene:GABRG2
Gene Synonym:
Exon (6)990..1127
Gene:GABRG2
Gene Synonym:
Exon (7)1128..1280
Gene:GABRG2
Gene Synonym:
Exon (8)1281..1486
Gene:GABRG2
Gene Synonym:
Exon (9)1487..3933
Gene:GABRG2
Gene Synonym:
Translation
Position Chain Variation Link
1 1 -, gtaa dbSNP:781608673
1 1 a, g dbSNP:535933351
5 5 a, g dbSNP:551085504
36 36 c, g dbSNP:373691169
77 77 c, t dbSNP:772816792
119 119 c, t dbSNP:114796537
140 140 a, g dbSNP:539867682
142 142 c, g dbSNP:748771306
150 150 c, t dbSNP:557868741
161 161 a, g dbSNP:573159939
179 179 a, g dbSNP:534235351
205 205 c, t dbSNP:3219203
213 213 a, g dbSNP:573923202
306 306 g, t dbSNP:541552445
313 313 c, t dbSNP:764214358
315 315 g, t dbSNP:367762747
320 320 a, c dbSNP:371508835
330 330 a, g dbSNP:757437605
334 334 c, g dbSNP:765592275
337 337 -, t dbSNP:36112889
337 337 a, g dbSNP:750851406
342 342 a, g dbSNP:758944561
342 342 -, g dbSNP:758313419
343 343 -, a, aa dbSNP:771282908
344 344 -, aaa dbSNP:781628762
344 344 -, aa dbSNP:777736322
344 344 -, a dbSNP:780201998
346 346 a, g dbSNP:780757403
349 349 a, g dbSNP:746505697
350 350 a, c dbSNP:754584418
358 358 a, g dbSNP:780572044
362 362 a, g dbSNP:747787220
365 365 c, t dbSNP:769362559
367 367 g, t dbSNP:55716248
369 369 a, c, t dbSNP:375295110
371 371 a, t dbSNP:774337016
375 375 c, t dbSNP:759392289
379 379 c, g dbSNP:764172866
382 382 a, c dbSNP:183259247
394 394 a, t dbSNP:762058667
399 399 a, g dbSNP:61750979
402 402 c, g dbSNP:750798004
410 410 c, g dbSNP:141106898
412 412 a, g dbSNP:200838780
436 436 a, g dbSNP:564088820
437 437 a, g dbSNP:766990192
446 446 -, ctg dbSNP:770106632
448 448 g, t dbSNP:115976622
457 457 c, t dbSNP:368162707
460 460 c, t dbSNP:780713471
461 461 c, t dbSNP:747649928
467 467 g, t dbSNP:753427115
480 480 a, c dbSNP:756921875
484 484 -, tga dbSNP:769160013
493 493 c, t dbSNP:375308385
496 496 c, t dbSNP:745694203
502 502 a, t dbSNP:772026488
505 505 g, t dbSNP:779917631
520 520 a, g dbSNP:748255945
521 521 -, g dbSNP:35315145
524 524 a, g dbSNP:530774170
529 529 g, t dbSNP:368962609
531 531 a, c dbSNP:763218917
543 543 c, t dbSNP:771317794
547 547 g, t dbSNP:774756037
548 548 a, g dbSNP:759874474
574 574 a, c dbSNP:768062008
576 576 c, t dbSNP:112586362
577 577 a, g dbSNP:753076158
594 594 a, g dbSNP:112894280
601 601 a, t dbSNP:143295869
602 602 c, t dbSNP:146470870
603 603 a, g dbSNP:121909673
604 604 a, g dbSNP:763542378
605 605 c, t dbSNP:587777365
614 614 a, g dbSNP:753381913
628 628 a, g dbSNP:758084555
638 638 a, g dbSNP:766039298
650 650 c, g dbSNP:751432250
653 653 a, c dbSNP:758970487
673 673 c, t dbSNP:11135176
691 691 c, t dbSNP:777192588
692 692 a, g dbSNP:111782778
694 694 a, t dbSNP:370890791
699 699 a, g dbSNP:764596401
709 709 g, t dbSNP:76898315
711 711 c, t dbSNP:772800839
712 712 a, g dbSNP:61735412
716 716 a, t dbSNP:766103158
718 718 a, g dbSNP:77298346
730 730 a, t dbSNP:754884716
733 733 c, t dbSNP:767423340
752 752 a, g dbSNP:752621588
760 760 c, g dbSNP:562384157
761 761 c, t dbSNP:74930063
765 765 a, g dbSNP:778814579
767 767 c, t dbSNP:200828542
782 782 a, g dbSNP:758530172
783 783 g, t dbSNP:780317346
786 786 a, g dbSNP:747372679
793 793 c, t dbSNP:768946471
799 799 c, t dbSNP:781551591
822 822 c, t dbSNP:267600531
825 825 a, g dbSNP:748607809
828 828 a, c dbSNP:770364855
839 839 c, t dbSNP:772566750
866 866 c, t dbSNP:762581269
883 883 c, t dbSNP:770485021
887 887 c, g dbSNP:267606837
910 910 a, g dbSNP:758574181
928 928 c, t dbSNP:564464466
937 937 a, g dbSNP:751723547
938 938 c, t dbSNP:755215653
940 940 a, g dbSNP:781498456
943 943 c, t dbSNP:150134470
946 946 c, t dbSNP:211037
952 952 a, g dbSNP:778408584
953 953 a, g dbSNP:749764060
954 954 a, t dbSNP:770506471
964 964 a, c dbSNP:774016949
967 967 c, t dbSNP:759221112
970 970 c, t dbSNP:771888226
985 985 a, c dbSNP:17855004
991 991 a, t dbSNP:779447500
1001 1001 c, t dbSNP:746626989
1013 1013 a, g dbSNP:768224402
1029 1029 a, g dbSNP:776456366
1048 1048 a, c, t dbSNP:747988447
1049 1049 a, g dbSNP:773065895
1060 1060 c, t dbSNP:762889745
1075 1075 a, g dbSNP:78261481
1076 1076 a, t dbSNP:52792201
1096 1096 a, g dbSNP:775462510
1102 1102 c, t dbSNP:760916801
1106 1106 a, g dbSNP:549251133
1111 1111 a, c dbSNP:764267675
1117 1117 a, g dbSNP:202124575
1126 1126 c, t dbSNP:201672465
1147 1147 g, t dbSNP:754514348
1152 1152 a, g dbSNP:780766516
1156 1156 c, t dbSNP:115126975
1168 1168 a, g dbSNP:200449368
1198 1198 c, t dbSNP:558779533
1201 1201 a, c dbSNP:749127891
1213 1213 c, t dbSNP:770884037
1219 1219 c, g, t dbSNP:778780107
1220 1220 a, g dbSNP:768565280
1222 1222 c, t dbSNP:372757018
1249 1249 c, t dbSNP:776876970
1257 1257 c, t dbSNP:543339576
1300 1300 a, g dbSNP:377502016
1312 1312 c, t dbSNP:749531013
1319 1319 a, g dbSNP:763639081
1326 1326 a, g dbSNP:397514737
1330 1330 a, g dbSNP:369614121
1333 1333 a, g dbSNP:774809218
1336 1336 c, t dbSNP:373993626
1341 1341 a, t dbSNP:121909672
1343 1343 g, t dbSNP:768061156
1345 1345 a, c dbSNP:774964109
1354 1354 c, t dbSNP:138964417
1357 1357 a, t dbSNP:377638785
1358 1358 a, g dbSNP:398123523
1360 1360 a, g dbSNP:371601817
1375 1375 a, t dbSNP:753372205
1403 1403 a, g dbSNP:756959300
1411 1411 a, g dbSNP:149472714
1428 1428 a, g dbSNP:17855003
1435 1435 c, t dbSNP:750277181
1445 1445 c, t dbSNP:374512652
1446 1446 a, g dbSNP:780199000
1451 1451 c, t dbSNP:377035112
1468 1468 a, t dbSNP:201824364
1469 1469 -, aaa dbSNP:749611954
1471 1471 -, aaa dbSNP:727503941
1477 1477 a, g dbSNP:571034662
1480 1480 a, g dbSNP:776166431
1487 1487 c, g dbSNP:2229946
1490 1490 c, t dbSNP:757311213
1505 1505 c, t dbSNP:768576864
1506 1506 a, g dbSNP:528036202
1507 1507 c, g dbSNP:761755629
1513 1513 a, t dbSNP:770952397
1514 1514 c, t dbSNP:774328514
1520 1520 a, g dbSNP:759779386
1523 1523 a, g dbSNP:375785093
1526 1526 c, t dbSNP:121909674
1529 1529 a, g dbSNP:753097258
1536 1536 a, t dbSNP:778999273
1538 1538 a, g, t dbSNP:143945240
1541 1541 a, g dbSNP:757868774
1553 1553 a, g dbSNP:778533443
1570 1570 c, t dbSNP:749951528
1588 1588 c, t dbSNP:113085352
1589 1589 a, g dbSNP:148232491
1590 1590 a, g dbSNP:746678010
1605 1605 a, g dbSNP:369200303
1607 1607 g, t dbSNP:780991820
1609 1609 c, t dbSNP:748041632
1618 1618 c, t dbSNP:141138508
1632 1632 a, g dbSNP:774474550
1640 1640 a, g dbSNP:759598497
1650 1650 a, t dbSNP:772194057
1654 1654 a, g dbSNP:150727562
1655 1655 a, g dbSNP:761000541
1660 1660 a, g dbSNP:760834360
1668 1668 g, t dbSNP:587780341
1670 1670 a, g dbSNP:764513577
1684 1684 c, t dbSNP:202246006
1690 1690 c, t dbSNP:762386331
1723 1723 a, g dbSNP:765904792
1737 1737 a, g dbSNP:749946230
1745 1745 c, t dbSNP:757781259
1747 1747 c, t dbSNP:765926862
1763 1763 a, g dbSNP:751127136
1773 1773 a, g dbSNP:754658882
1777 1777 c, t dbSNP:780936760
1785 1785 c, t dbSNP:747992571
1787 1787 a, g dbSNP:756037476
1792 1792 c, t dbSNP:777501290
1794 1794 c, t dbSNP:749257839
1802 1802 c, g dbSNP:771995505
1803 1803 c, t dbSNP:373649929
1804 1804 c, t dbSNP:747202413
1805 1805 c, t dbSNP:769046548
1807 1807 a, t dbSNP:777124332
1808 1808 a, t dbSNP:762335640
1809 1809 -, agagactgagagtctcact dbSNP:775151354
1809 1809 a, g dbSNP:765639964
1811 1811 -, gagatgtctgt dbSNP:762872104
1813 1813 a, g dbSNP:370402998
1847 1847 -, ta dbSNP:771639644
1863 1863 a, g dbSNP:750904065
1879 1879 a, c dbSNP:187224842
1899 1899 g, t dbSNP:145318600
1955 1955 c, t dbSNP:539963242
1956 1956 a, g dbSNP:758832535
1977 1977 a, c dbSNP:558250245
2009 2009 c, t dbSNP:371389067
2023 2023 a, g dbSNP:148001179
2051 2051 a, t dbSNP:769488331
2075 2075 a, t dbSNP:534139912
2105 2105 a, g dbSNP:41275341
2110 2110 a, g dbSNP:192973258
2136 2136 a, g dbSNP:573126853
2146 2146 c, t dbSNP:773854777
2147 2147 a, g dbSNP:185169107
2150 2150 c, t dbSNP:759550610
2172 2172 c, g dbSNP:556737874
2184 2184 c, t dbSNP:752382943
2198 2198 a, g dbSNP:3180569
2203 2203 a, c, t dbSNP:188825588
2279 2279 c, g dbSNP:563791011
2312 2312 -, aataacttagaat dbSNP:769280685
2313 2313 a, g dbSNP:528169677
2317 2317 a, c dbSNP:193024691
2345 2345 a, g dbSNP:556132977
2352 2352 c, t dbSNP:540625537
2371 2371 c, t dbSNP:418210
2406 2406 c, t dbSNP:532694990
2415 2415 a, g dbSNP:550574038
2423 2423 a, t dbSNP:424740
2460 2460 a, g dbSNP:563105218
2480 2480 c, g dbSNP:762034001
2486 2486 c, g dbSNP:765232468
2504 2504 c, t dbSNP:367757836
2505 2505 a, g dbSNP:116673668
2528 2528 a, t dbSNP:750509121
2556 2556 a, g dbSNP:73316347
2559 2559 g, t dbSNP:118064447
2603 2603 a, t dbSNP:371240534
2638 2638 a, g dbSNP:758965402
2665 2665 c, t dbSNP:534017024
2690 2690 -, a dbSNP:756746053
2709 2709 a, g dbSNP:766852844
2764 2764 a, g dbSNP:555757475
2778 2778 g, t dbSNP:567521884
2807 2807 a, g dbSNP:41304898
2828 2828 a, t dbSNP:538544011
2832 2832 a, g dbSNP:375311334
2852 2852 c, t dbSNP:751962818
2886 2886 g, t dbSNP:755370766
2925 2925 c, t dbSNP:556537352
2942 2942 c, t dbSNP:577817884
2955 2955 c, t dbSNP:184725064
3004 3004 a, t dbSNP:553936990
3031 3031 c, t dbSNP:781573317
3061 3061 a, g dbSNP:572636789
3120 3120 g, t dbSNP:530406856
3162 3162 c, t dbSNP:539929585
3163 3163 c, t dbSNP:780622182
3169 3169 a, t dbSNP:748908802
3189 3189 c, t dbSNP:375013278
3190 3190 a, g dbSNP:367974933
3191 3191 -, a dbSNP:34809383
3204 3204 a, g dbSNP:111695377
3230 3230 a, g dbSNP:372041761
3252 3252 g, t dbSNP:553454795
3255 3255 g, t dbSNP:548569193
3259 3259 c, t dbSNP:11956247
3278 3278 a, c, g dbSNP:745348234
3280 3280 a, g dbSNP:567153845
3286 3286 c, t dbSNP:746892139
3297 3297 c, t dbSNP:533511123
3303 3303 a, t dbSNP:562728260
3312 3312 a, g dbSNP:578039218
3340 3340 a, g dbSNP:545350783
3363 3363 c, t dbSNP:768346662
3398 3398 c, t dbSNP:551794496
3420 3420 c, g dbSNP:570208308
3422 3422 c, g dbSNP:755680345
3447 3447 c, t dbSNP:557096441
3470 3470 c, t dbSNP:188046779
3472 3472 a, g dbSNP:566646982
3477 3477 c, g dbSNP:376466092
3610 3610 c, t dbSNP:762003732
3636 3636 c, t dbSNP:537576088
3656 3656 c, t dbSNP:779806977
3689 3689 a, c dbSNP:112419308
3697 3697 a, g dbSNP:765480194
3717 3717 g, t dbSNP:180905867
3729 3729 a, g dbSNP:748432555
3730 3730 g, t dbSNP:549173529
3736 3736 a, g dbSNP:150875037
3789 3789 a, c dbSNP:766408832
3844 3844 c, t dbSNP:752085538
3846 3846 c, t dbSNP:755422089
3857 3857 c, g dbSNP:138297122
3881 3881 -, at dbSNP:767716700
3882 3882 -, at dbSNP:34705786
3883 3883 c, t dbSNP:200339735
3909 3909 c, t dbSNP:183746824
3926 3926 a, g dbSNP:189481479

Target ORF information:

RefSeq Version NM_000816
Organism Homo sapiens (human)
Definition Homo sapiens gamma-aminobutyric acid (GABA) A receptor, gamma 2 (GABRG2), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_000816

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGAGTTCGC CAAATATATG GAGCACAGGA AGCTCAGTCT ACTCGACTCC TGTATTTTCA 
CAGAAAATGA CGGTGTGGAT TCTGCTCCTG CTGTCGCTCT ACCCTGGCTT CACTAGCCAG
AAATCTGATG ATGACTATGA AGATTATGCT TCTAACAAAA CATGGGTCTT GACTCCAAAA
GTTCCTGAGG GTGATGTCAC TGTCATCTTA AACAACCTGC TGGAAGGATA TGACAATAAA
CTTCGGCCTG ATATAGGAGT GAAGCCAACG TTAATTCACA CAGACATGTA TGTGAATAGC
ATTGGTCCAG TGAACGCTAT CAATATGGAA TACACTATTG ATATATTTTT TGCGCAAACG
TGGTATGACA GACGTTTGAA ATTTAACAGC ACCATTAAAG TCCTCCGATT GAACAGCAAC
ATGGTGGGGA AAATCTGGAT TCCAGACACT TTCTTCAGAA ATTCCAAAAA AGCTGATGCA
CACTGGATCA CCACCCCCAA CAGGATGCTG AGAATTTGGA ATGATGGTCG AGTGCTCTAC
ACCCTAAGGT TGACAATTGA TGCTGAGTGC CAATTACAAT TGCACAACTT TCCAATGGAT
GAACACTCCT GCCCCTTGGA GTTCTCCAGT TATGGCTATC CACGTGAAGA AATTGTTTAT
CAATGGAAGC GAAGTTCTGT TGAAGTGGGC GACACAAGAT CCTGGAGGCT TTATCAATTC
TCATTTGTTG GTCTAAGAAA TACCACCGAA GTAGTGAAGA CAACTTCCGG AGATTATGTG
GTCATGTCTG TCTACTTTGA TCTGAGCAGA AGAATGGGAT ACTTTACCAT CCAGACCTAT
ATCCCCTGCA CACTCATTGT CGTCCTATCC TGGGTGTCTT TCTGGATCAA TAAGGATGCT
GTTCCAGCCA GAACATCTTT AGGTATCACC ACTGTCCTGA CAATGACCAC CCTCAGCACC
ATTGCCCGGA AATCGCTCCC CAAGGTCTCC TATGTCACAG CGATGGATCT CTTTGTATCT
GTTTGTTTCA TCTTTGTCTT CTCTGCTCTG GTGGAGTATG GCACCTTGCA TTATTTTGTC
AGCAACCGGA AACCAAGCAA GGACAAAGAT AAAAAGAAGA AAAACCCTGC CCCTACCATT
GATATCCGCC CAAGATCAGC AACCATTCAA ATGAATAATG CTACACACCT TCAAGAGAGA
GATGAAGAGT ACGGCTATGA GTGTCTGGAC GGCAAGGACT GTGCCAGTTT TTTCTGCTGT
TTTGAAGATT GTCGAACAGG AGCTTGGAGA CATGGGAGGA TACATATCCG CATTGCCAAA
ATGGACTCCT ATGCTCGGAT CTTCTTCCCC ACTGCCTTCT GCCTGTTTAA TCTGGTCTAT
TGGGTCTCCT ACCTCTACCT GTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu17503
Accession Version NM_198904.2
Sequence Information ORF Nucleotide Sequence (Length: 1428bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product gamma-aminobutyric acid receptor subunit gamma-2 isoform 1 precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA226729.1, BC052926.1, BC059389.1 and AC091984.3. On May 24, 2008 this sequence version replaced gi:38788154. Summary: This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammlian brain, where it acts at GABA-A receptors, which are ligand-gated chloride channels. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene have been associated with epilepsy and febrile seizures. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]. Transcript Variant: This variant (1) lacks an alternate in-frame exon, compared to variant 3. It encodes isoform 1 which is shorter than isoform 3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC059389.1, CD013896.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145743, SAMEA2154665 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGAGTTCGC CAAATATATG GAGCACAGGA AGCTCAGTCT ACTCGACTCC TGTATTTTCA 
CAGAAAATGA CGGTGTGGAT TCTGCTCCTG CTGTCGCTCT ACCCTGGCTT CACTAGCCAG
AAATCTGATG ATGACTATGA AGATTATGCT TCTAACAAAA CATGGGTCTT GACTCCAAAA
GTTCCTGAGG GTGATGTCAC TGTCATCTTA AACAACCTGC TGGAAGGATA TGACAATAAA
CTTCGGCCTG ATATAGGAGT GAAGCCAACG TTAATTCACA CAGACATGTA TGTGAATAGC
ATTGGTCCAG TGAACGCTAT CAATATGGAA TACACTATTG ATATATTTTT TGCGCAAACG
TGGTATGACA GACGTTTGAA ATTTAACAGC ACCATTAAAG TCCTCCGATT GAACAGCAAC
ATGGTGGGGA AAATCTGGAT TCCAGACACT TTCTTCAGAA ATTCCAAAAA AGCTGATGCA
CACTGGATCA CCACCCCCAA CAGGATGCTG AGAATTTGGA ATGATGGTCG AGTGCTCTAC
ACCCTAAGGT TGACAATTGA TGCTGAGTGC CAATTACAAT TGCACAACTT TCCAATGGAT
GAACACTCCT GCCCCTTGGA GTTCTCCAGT TATGGCTATC CACGTGAAGA AATTGTTTAT
CAATGGAAGC GAAGTTCTGT TGAAGTGGGC GACACAAGAT CCTGGAGGCT TTATCAATTC
TCATTTGTTG GTCTAAGAAA TACCACCGAA GTAGTGAAGA CAACTTCCGG AGATTATGTG
GTCATGTCTG TCTACTTTGA TCTGAGCAGA AGAATGGGAT ACTTTACCAT CCAGACCTAT
ATCCCCTGCA CACTCATTGT CGTCCTATCC TGGGTGTCTT TCTGGATCAA TAAGGATGCT
GTTCCAGCCA GAACATCTTT AGGTATCACC ACTGTCCTGA CAATGACCAC CCTCAGCACC
ATTGCCCGGA AATCGCTCCC CAAGGTCTCC TATGTCACAG CGATGGATCT CTTTGTATCT
GTTTGTTTCA TCTTTGTCTT CTCTGCTCTG GTGGAGTATG GCACCTTGCA TTATTTTGTC
AGCAACCGGA AACCAAGCAA GGACAAAGAT AAAAAGAAGA AAAACCCTCT TCTTCGGATG
TTTTCCTTCA AGGCCCCTAC CATTGATATC CGCCCAAGAT CAGCAACCAT TCAAATGAAT
AATGCTACAC ACCTTCAAGA GAGAGATGAA GAGTACGGCT ATGAGTGTCT GGACGGCAAG
GACTGTGCCA GTTTTTTCTG CTGTTTTGAA GATTGTCGAA CAGGAGCTTG GAGACATGGG
AGGATACATA TCCGCATTGC CAAAATGGAC TCCTATGCTC GGATCTTCTT CCCCACTGCC
TTCTGCCTGT TTAATCTGGT CTATTGGGTC TCCTACCTCT ACCTGTGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_944494.1
CDS359..1786
Misc Feature(1)290..292(+)
Misc Feature(2)563..1774(+)
Misc Feature(3)563..1174(+)
Misc Feature(4)1178..1246(+)
Misc Feature(5)1193..1765(+)
Misc Feature(6)1256..1324(+)
Misc Feature(7)1358..1426(+)
Misc Feature(8)1454..1456(+)
Misc Feature(9)1655..1708(+)
Misc Feature(10)1712..1780(+)
Exon (1)1..465
Gene:GABRG2
Gene Synonym:
Exon (2)466..617
Gene:GABRG2
Gene Synonym:
Exon (3)618..685
Gene:GABRG2
Gene Synonym:
Exon (4)686..906
Gene:GABRG2
Gene Synonym:
Exon (5)907..989
Gene:GABRG2
Gene Synonym:
Exon (6)990..1127
Gene:GABRG2
Gene Synonym:
Exon (7)1128..1280
Gene:GABRG2
Gene Synonym:
Exon (8)1281..1486
Gene:GABRG2
Gene Synonym:
Exon (9)1487..1510
Gene:GABRG2
Gene Synonym:
Exon (10)1511..3957
Gene:GABRG2
Gene Synonym:
Translation
Position Chain Variation Link
1 1 -, gtaa dbSNP:781608673
1 1 a, g dbSNP:535933351
5 5 a, g dbSNP:551085504
36 36 c, g dbSNP:373691169
77 77 c, t dbSNP:772816792
119 119 c, t dbSNP:114796537
140 140 a, g dbSNP:539867682
142 142 c, g dbSNP:748771306
150 150 c, t dbSNP:557868741
161 161 a, g dbSNP:573159939
179 179 a, g dbSNP:534235351
205 205 c, t dbSNP:3219203
213 213 a, g dbSNP:573923202
306 306 g, t dbSNP:541552445
313 313 c, t dbSNP:764214358
315 315 g, t dbSNP:367762747
320 320 a, c dbSNP:371508835
330 330 a, g dbSNP:757437605
334 334 c, g dbSNP:765592275
337 337 -, t dbSNP:36112889
337 337 a, g dbSNP:750851406
342 342 a, g dbSNP:758944561
342 342 -, g dbSNP:758313419
343 343 -, a, aa dbSNP:771282908
344 344 -, aaa dbSNP:781628762
344 344 -, aa dbSNP:777736322
344 344 -, a dbSNP:780201998
346 346 a, g dbSNP:780757403
349 349 a, g dbSNP:746505697
350 350 a, c dbSNP:754584418
358 358 a, g dbSNP:780572044
362 362 a, g dbSNP:747787220
365 365 c, t dbSNP:769362559
367 367 g, t dbSNP:55716248
369 369 a, c, t dbSNP:375295110
371 371 a, t dbSNP:774337016
375 375 c, t dbSNP:759392289
379 379 c, g dbSNP:764172866
382 382 a, c dbSNP:183259247
394 394 a, t dbSNP:762058667
399 399 a, g dbSNP:61750979
402 402 c, g dbSNP:750798004
410 410 c, g dbSNP:141106898
412 412 a, g dbSNP:200838780
436 436 a, g dbSNP:564088820
437 437 a, g dbSNP:766990192
446 446 -, ctg dbSNP:770106632
448 448 g, t dbSNP:115976622
457 457 c, t dbSNP:368162707
460 460 c, t dbSNP:780713471
461 461 c, t dbSNP:747649928
467 467 g, t dbSNP:753427115
480 480 a, c dbSNP:756921875
484 484 -, tga dbSNP:769160013
493 493 c, t dbSNP:375308385
496 496 c, t dbSNP:745694203
502 502 a, t dbSNP:772026488
505 505 g, t dbSNP:779917631
520 520 a, g dbSNP:748255945
521 521 -, g dbSNP:35315145
524 524 a, g dbSNP:530774170
529 529 g, t dbSNP:368962609
531 531 a, c dbSNP:763218917
543 543 c, t dbSNP:771317794
547 547 g, t dbSNP:774756037
548 548 a, g dbSNP:759874474
574 574 a, c dbSNP:768062008
576 576 c, t dbSNP:112586362
577 577 a, g dbSNP:753076158
594 594 a, g dbSNP:112894280
601 601 a, t dbSNP:143295869
602 602 c, t dbSNP:146470870
603 603 a, g dbSNP:121909673
604 604 a, g dbSNP:763542378
605 605 c, t dbSNP:587777365
614 614 a, g dbSNP:753381913
628 628 a, g dbSNP:758084555
638 638 a, g dbSNP:766039298
650 650 c, g dbSNP:751432250
653 653 a, c dbSNP:758970487
673 673 c, t dbSNP:11135176
691 691 c, t dbSNP:777192588
692 692 a, g dbSNP:111782778
694 694 a, t dbSNP:370890791
699 699 a, g dbSNP:764596401
709 709 g, t dbSNP:76898315
711 711 c, t dbSNP:772800839
712 712 a, g dbSNP:61735412
716 716 a, t dbSNP:766103158
718 718 a, g dbSNP:77298346
730 730 a, t dbSNP:754884716
733 733 c, t dbSNP:767423340
752 752 a, g dbSNP:752621588
760 760 c, g dbSNP:562384157
761 761 c, t dbSNP:74930063
765 765 a, g dbSNP:778814579
767 767 c, t dbSNP:200828542
782 782 a, g dbSNP:758530172
783 783 g, t dbSNP:780317346
786 786 a, g dbSNP:747372679
793 793 c, t dbSNP:768946471
799 799 c, t dbSNP:781551591
822 822 c, t dbSNP:267600531
825 825 a, g dbSNP:748607809
828 828 a, c dbSNP:770364855
839 839 c, t dbSNP:772566750
866 866 c, t dbSNP:762581269
883 883 c, t dbSNP:770485021
887 887 c, g dbSNP:267606837
910 910 a, g dbSNP:758574181
928 928 c, t dbSNP:564464466
937 937 a, g dbSNP:751723547
938 938 c, t dbSNP:755215653
940 940 a, g dbSNP:781498456
943 943 c, t dbSNP:150134470
946 946 c, t dbSNP:211037
952 952 a, g dbSNP:778408584
953 953 a, g dbSNP:749764060
954 954 a, t dbSNP:770506471
964 964 a, c dbSNP:774016949
967 967 c, t dbSNP:759221112
970 970 c, t dbSNP:771888226
985 985 a, c dbSNP:17855004
991 991 a, t dbSNP:779447500
1001 1001 c, t dbSNP:746626989
1013 1013 a, g dbSNP:768224402
1029 1029 a, g dbSNP:776456366
1048 1048 a, c, t dbSNP:747988447
1049 1049 a, g dbSNP:773065895
1060 1060 c, t dbSNP:762889745
1075 1075 a, g dbSNP:78261481
1076 1076 a, t dbSNP:52792201
1096 1096 a, g dbSNP:775462510
1102 1102 c, t dbSNP:760916801
1106 1106 a, g dbSNP:549251133
1111 1111 a, c dbSNP:764267675
1117 1117 a, g dbSNP:202124575
1126 1126 c, t dbSNP:201672465
1147 1147 g, t dbSNP:754514348
1152 1152 a, g dbSNP:780766516
1156 1156 c, t dbSNP:115126975
1168 1168 a, g dbSNP:200449368
1198 1198 c, t dbSNP:558779533
1201 1201 a, c dbSNP:749127891
1213 1213 c, t dbSNP:770884037
1219 1219 c, g, t dbSNP:778780107
1220 1220 a, g dbSNP:768565280
1222 1222 c, t dbSNP:372757018
1249 1249 c, t dbSNP:776876970
1257 1257 c, t dbSNP:543339576
1300 1300 a, g dbSNP:377502016
1312 1312 c, t dbSNP:749531013
1319 1319 a, g dbSNP:763639081
1326 1326 a, g dbSNP:397514737
1330 1330 a, g dbSNP:369614121
1333 1333 a, g dbSNP:774809218
1336 1336 c, t dbSNP:373993626
1341 1341 a, t dbSNP:121909672
1343 1343 g, t dbSNP:768061156
1345 1345 a, c dbSNP:774964109
1354 1354 c, t dbSNP:138964417
1357 1357 a, t dbSNP:377638785
1358 1358 a, g dbSNP:398123523
1360 1360 a, g dbSNP:371601817
1375 1375 a, t dbSNP:753372205
1403 1403 a, g dbSNP:756959300
1411 1411 a, g dbSNP:149472714
1428 1428 a, g dbSNP:17855003
1435 1435 c, t dbSNP:750277181
1445 1445 c, t dbSNP:374512652
1446 1446 a, g dbSNP:780199000
1451 1451 c, t dbSNP:377035112
1468 1468 a, t dbSNP:201824364
1469 1469 -, aaa dbSNP:749611954
1471 1471 -, aaa dbSNP:727503941
1477 1477 a, g dbSNP:571034662
1480 1480 a, g dbSNP:776166431
1489 1489 g, t dbSNP:780368645
1493 1493 c, t dbSNP:747426141
1494 1494 a, g dbSNP:755430911
1499 1499 c, t dbSNP:199574539
1501 1501 g, t dbSNP:781756750
1503 1503 c, t dbSNP:267600532
1511 1511 c, g dbSNP:2229946
1514 1514 c, t dbSNP:757311213
1529 1529 c, t dbSNP:768576864
1530 1530 a, g dbSNP:528036202
1531 1531 c, g dbSNP:761755629
1537 1537 a, t dbSNP:770952397
1538 1538 c, t dbSNP:774328514
1544 1544 a, g dbSNP:759779386
1547 1547 a, g dbSNP:375785093
1550 1550 c, t dbSNP:121909674
1553 1553 a, g dbSNP:753097258
1560 1560 a, t dbSNP:778999273
1562 1562 a, g, t dbSNP:143945240
1565 1565 a, g dbSNP:757868774
1577 1577 a, g dbSNP:778533443
1594 1594 c, t dbSNP:749951528
1612 1612 c, t dbSNP:113085352
1613 1613 a, g dbSNP:148232491
1614 1614 a, g dbSNP:746678010
1629 1629 a, g dbSNP:369200303
1631 1631 g, t dbSNP:780991820
1633 1633 c, t dbSNP:748041632
1642 1642 c, t dbSNP:141138508
1656 1656 a, g dbSNP:774474550
1664 1664 a, g dbSNP:759598497
1674 1674 a, t dbSNP:772194057
1678 1678 a, g dbSNP:150727562
1679 1679 a, g dbSNP:761000541
1684 1684 a, g dbSNP:760834360
1692 1692 g, t dbSNP:587780341
1694 1694 a, g dbSNP:764513577
1708 1708 c, t dbSNP:202246006
1714 1714 c, t dbSNP:762386331
1747 1747 a, g dbSNP:765904792
1761 1761 a, g dbSNP:749946230
1769 1769 c, t dbSNP:757781259
1771 1771 c, t dbSNP:765926862
1787 1787 a, g dbSNP:751127136
1797 1797 a, g dbSNP:754658882
1801 1801 c, t dbSNP:780936760
1809 1809 c, t dbSNP:747992571
1811 1811 a, g dbSNP:756037476
1816 1816 c, t dbSNP:777501290
1818 1818 c, t dbSNP:749257839
1826 1826 c, g dbSNP:771995505
1827 1827 c, t dbSNP:373649929
1828 1828 c, t dbSNP:747202413
1829 1829 c, t dbSNP:769046548
1831 1831 a, t dbSNP:777124332
1832 1832 a, t dbSNP:762335640
1833 1833 -, agagactgagagtctcact dbSNP:775151354
1833 1833 a, g dbSNP:765639964
1835 1835 -, gagatgtctgt dbSNP:762872104
1837 1837 a, g dbSNP:370402998
1871 1871 -, ta dbSNP:771639644
1887 1887 a, g dbSNP:750904065
1903 1903 a, c dbSNP:187224842
1923 1923 g, t dbSNP:145318600
1979 1979 c, t dbSNP:539963242
1980 1980 a, g dbSNP:758832535
2001 2001 a, c dbSNP:558250245
2033 2033 c, t dbSNP:371389067
2047 2047 a, g dbSNP:148001179
2075 2075 a, t dbSNP:769488331
2099 2099 a, t dbSNP:534139912
2129 2129 a, g dbSNP:41275341
2134 2134 a, g dbSNP:192973258
2160 2160 a, g dbSNP:573126853
2170 2170 c, t dbSNP:773854777
2171 2171 a, g dbSNP:185169107
2174 2174 c, t dbSNP:759550610
2196 2196 c, g dbSNP:556737874
2208 2208 c, t dbSNP:752382943
2222 2222 a, g dbSNP:3180569
2227 2227 a, c, t dbSNP:188825588
2303 2303 c, g dbSNP:563791011
2336 2336 -, aataacttagaat dbSNP:769280685
2337 2337 a, g dbSNP:528169677
2341 2341 a, c dbSNP:193024691
2369 2369 a, g dbSNP:556132977
2376 2376 c, t dbSNP:540625537
2395 2395 c, t dbSNP:418210
2430 2430 c, t dbSNP:532694990
2439 2439 a, g dbSNP:550574038
2447 2447 a, t dbSNP:424740
2484 2484 a, g dbSNP:563105218
2504 2504 c, g dbSNP:762034001
2510 2510 c, g dbSNP:765232468
2528 2528 c, t dbSNP:367757836
2529 2529 a, g dbSNP:116673668
2552 2552 a, t dbSNP:750509121
2580 2580 a, g dbSNP:73316347
2583 2583 g, t dbSNP:118064447
2627 2627 a, t dbSNP:371240534
2662 2662 a, g dbSNP:758965402
2689 2689 c, t dbSNP:534017024
2714 2714 -, a dbSNP:756746053
2733 2733 a, g dbSNP:766852844
2788 2788 a, g dbSNP:555757475
2802 2802 g, t dbSNP:567521884
2831 2831 a, g dbSNP:41304898
2852 2852 a, t dbSNP:538544011
2856 2856 a, g dbSNP:375311334
2876 2876 c, t dbSNP:751962818
2910 2910 g, t dbSNP:755370766
2949 2949 c, t dbSNP:556537352
2966 2966 c, t dbSNP:577817884
2979 2979 c, t dbSNP:184725064
3028 3028 a, t dbSNP:553936990
3055 3055 c, t dbSNP:781573317
3085 3085 a, g dbSNP:572636789
3144 3144 g, t dbSNP:530406856
3186 3186 c, t dbSNP:539929585
3187 3187 c, t dbSNP:780622182
3193 3193 a, t dbSNP:748908802
3213 3213 c, t dbSNP:375013278
3214 3214 a, g dbSNP:367974933
3215 3215 -, a dbSNP:34809383
3228 3228 a, g dbSNP:111695377
3254 3254 a, g dbSNP:372041761
3276 3276 g, t dbSNP:553454795
3279 3279 g, t dbSNP:548569193
3283 3283 c, t dbSNP:11956247
3302 3302 a, c, g dbSNP:745348234
3304 3304 a, g dbSNP:567153845
3310 3310 c, t dbSNP:746892139
3321 3321 c, t dbSNP:533511123
3327 3327 a, t dbSNP:562728260
3336 3336 a, g dbSNP:578039218
3364 3364 a, g dbSNP:545350783
3387 3387 c, t dbSNP:768346662
3422 3422 c, t dbSNP:551794496
3444 3444 c, g dbSNP:570208308
3446 3446 c, g dbSNP:755680345
3471 3471 c, t dbSNP:557096441
3494 3494 c, t dbSNP:188046779
3496 3496 a, g dbSNP:566646982
3501 3501 c, g dbSNP:376466092
3634 3634 c, t dbSNP:762003732
3660 3660 c, t dbSNP:537576088
3680 3680 c, t dbSNP:779806977
3713 3713 a, c dbSNP:112419308
3721 3721 a, g dbSNP:765480194
3741 3741 g, t dbSNP:180905867
3753 3753 a, g dbSNP:748432555
3754 3754 g, t dbSNP:549173529
3760 3760 a, g dbSNP:150875037
3813 3813 a, c dbSNP:766408832
3868 3868 c, t dbSNP:752085538
3870 3870 c, t dbSNP:755422089
3881 3881 c, g dbSNP:138297122
3905 3905 -, at dbSNP:767716700
3906 3906 -, at dbSNP:34705786
3907 3907 c, t dbSNP:200339735
3933 3933 c, t dbSNP:183746824
3950 3950 a, g dbSNP:189481479

Target ORF information:

RefSeq Version NM_198904
Organism Homo sapiens (human)
Definition Homo sapiens gamma-aminobutyric acid (GABA) A receptor, gamma 2 (GABRG2), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_198904

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGAGTTCGC CAAATATATG GAGCACAGGA AGCTCAGTCT ACTCGACTCC TGTATTTTCA 
CAGAAAATGA CGGTGTGGAT TCTGCTCCTG CTGTCGCTCT ACCCTGGCTT CACTAGCCAG
AAATCTGATG ATGACTATGA AGATTATGCT TCTAACAAAA CATGGGTCTT GACTCCAAAA
GTTCCTGAGG GTGATGTCAC TGTCATCTTA AACAACCTGC TGGAAGGATA TGACAATAAA
CTTCGGCCTG ATATAGGAGT GAAGCCAACG TTAATTCACA CAGACATGTA TGTGAATAGC
ATTGGTCCAG TGAACGCTAT CAATATGGAA TACACTATTG ATATATTTTT TGCGCAAACG
TGGTATGACA GACGTTTGAA ATTTAACAGC ACCATTAAAG TCCTCCGATT GAACAGCAAC
ATGGTGGGGA AAATCTGGAT TCCAGACACT TTCTTCAGAA ATTCCAAAAA AGCTGATGCA
CACTGGATCA CCACCCCCAA CAGGATGCTG AGAATTTGGA ATGATGGTCG AGTGCTCTAC
ACCCTAAGGT TGACAATTGA TGCTGAGTGC CAATTACAAT TGCACAACTT TCCAATGGAT
GAACACTCCT GCCCCTTGGA GTTCTCCAGT TATGGCTATC CACGTGAAGA AATTGTTTAT
CAATGGAAGC GAAGTTCTGT TGAAGTGGGC GACACAAGAT CCTGGAGGCT TTATCAATTC
TCATTTGTTG GTCTAAGAAA TACCACCGAA GTAGTGAAGA CAACTTCCGG AGATTATGTG
GTCATGTCTG TCTACTTTGA TCTGAGCAGA AGAATGGGAT ACTTTACCAT CCAGACCTAT
ATCCCCTGCA CACTCATTGT CGTCCTATCC TGGGTGTCTT TCTGGATCAA TAAGGATGCT
GTTCCAGCCA GAACATCTTT AGGTATCACC ACTGTCCTGA CAATGACCAC CCTCAGCACC
ATTGCCCGGA AATCGCTCCC CAAGGTCTCC TATGTCACAG CGATGGATCT CTTTGTATCT
GTTTGTTTCA TCTTTGTCTT CTCTGCTCTG GTGGAGTATG GCACCTTGCA TTATTTTGTC
AGCAACCGGA AACCAAGCAA GGACAAAGAT AAAAAGAAGA AAAACCCTCT TCTTCGGATG
TTTTCCTTCA AGGCCCCTAC CATTGATATC CGCCCAAGAT CAGCAACCAT TCAAATGAAT
AATGCTACAC ACCTTCAAGA GAGAGATGAA GAGTACGGCT ATGAGTGTCT GGACGGCAAG
GACTGTGCCA GTTTTTTCTG CTGTTTTGAA GATTGTCGAA CAGGAGCTTG GAGACATGGG
AGGATACATA TCCGCATTGC CAAAATGGAC TCCTATGCTC GGATCTTCTT CCCCACTGCC
TTCTGCCTGT TTAATCTGGT CTATTGGGTC TCCTACCTCT ACCTGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu18155
Accession Version NM_198903.2
Sequence Information ORF Nucleotide Sequence (Length: 1548bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product gamma-aminobutyric acid receptor subunit gamma-2 isoform 3 precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC008611.6, AC091926.4 and AC091984.3. This sequence is a reference standard in the RefSeqGene project. On May 24, 2008 this sequence version replaced gi:38788149. Summary: This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammlian brain, where it acts at GABA-A receptors, which are ligand-gated chloride channels. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene have been associated with epilepsy and febrile seizures. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]. Transcript Variant: This variant (3) encodes the longest isoform (3). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC036030.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1966682, SAMEA1968540 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGAGTTCGC CAAATATATG GAGCACAGGA AGCTCAGTCT ACTCGACTCC TGTATTTTCA 
CAGAAAATGA CGGTGTGGAT TCTGCTCCTG CTGTCGCTCT ACCCTGGCTT CACTAGCCAG
AAATCTGATG ATGACTATGA AGATTATGCT TCTAACAAAA CATGGGTCTT GACTCCAAAA
GTTCCTGAGG GTGATGTCAC TGTCATCTTA AACAACCTGC TGGAAGGATA TGACAATAAA
CTTCGGCCTG ATATAGGAGT GAAGCCAACG TTAATTCACA CAGACATGTA TGTGAATAGC
ATTGGTCCAG TGAACGCTAT CAATATGGAA TACACTATTG ATATATTTTT TGCGCAAACG
TGGTATGACA GACGTTTGAA ATTTAACAGC ACCATTAAAG TCCTCCGATT GAACAGCAAC
ATGGTGGGGA AAATCTGGAT TCCAGACACT TTCTTCAGAA ATTCCAAAAA AGCTGATGCA
CACTGGATCA CCACCCCCAA CAGGATGCTG AGAATTTGGA ATGATGGTCG AGTGCTCTAC
ACCCTAAGGT TGACAATTGA TGCTGAGTGC CAATTACAAT TGCACAACTT TCCAATGGAT
GAACACTCCT GCCCCTTGGA GTTCTCCAGT TGGTCTCGTT CTATTGCCCA GGCTGGAATG
TGCAGTGGTG TGATCTCGGC TCACTACAGC CTTCGCTTCT GGGGCTCAAC TGATCCTCCC
ACCTTGGCCT CCAGAGTAGC TGGGATTTCA GATGGCTATC CACGTGAAGA AATTGTTTAT
CAATGGAAGC GAAGTTCTGT TGAAGTGGGC GACACAAGAT CCTGGAGGCT TTATCAATTC
TCATTTGTTG GTCTAAGAAA TACCACCGAA GTAGTGAAGA CAACTTCCGG AGATTATGTG
GTCATGTCTG TCTACTTTGA TCTGAGCAGA AGAATGGGAT ACTTTACCAT CCAGACCTAT
ATCCCCTGCA CACTCATTGT CGTCCTATCC TGGGTGTCTT TCTGGATCAA TAAGGATGCT
GTTCCAGCCA GAACATCTTT AGGTATCACC ACTGTCCTGA CAATGACCAC CCTCAGCACC
ATTGCCCGGA AATCGCTCCC CAAGGTCTCC TATGTCACAG CGATGGATCT CTTTGTATCT
GTTTGTTTCA TCTTTGTCTT CTCTGCTCTG GTGGAGTATG GCACCTTGCA TTATTTTGTC
AGCAACCGGA AACCAAGCAA GGACAAAGAT AAAAAGAAGA AAAACCCTCT TCTTCGGATG
TTTTCCTTCA AGGCCCCTAC CATTGATATC CGCCCAAGAT CAGCAACCAT TCAAATGAAT
AATGCTACAC ACCTTCAAGA GAGAGATGAA GAGTACGGCT ATGAGTGTCT GGACGGCAAG
GACTGTGCCA GTTTTTTCTG CTGTTTTGAA GATTGTCGAA CAGGAGCTTG GAGACATGGG
AGGATACATA TCCGCATTGC CAAAATGGAC TCCTATGCTC GGATCTTCTT CCCCACTGCC
TTCTGCCTGT TTAATCTGGT CTATTGGGTC TCCTACCTCT ACCTGTGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_944493.2
CDS359..1906
Misc Feature(1)290..292(+)
Misc Feature(2)563..1894(+)
Misc Feature(3)563..1294(+)
Misc Feature(4)1313..1885(+)
Exon (1)1..465
Gene:GABRG2
Gene Synonym:
Exon (2)466..617
Gene:GABRG2
Gene Synonym:
Exon (3)618..685
Gene:GABRG2
Gene Synonym:
Exon (4)686..906
Gene:GABRG2
Gene Synonym:
Exon (5)907..989
Gene:GABRG2
Gene Synonym:
Exon (6)990..1109
Gene:GABRG2
Gene Synonym:
Exon (7)1110..1247
Gene:GABRG2
Gene Synonym:
Exon (8)1248..1400
Gene:GABRG2
Gene Synonym:
Exon (9)1401..1606
Gene:GABRG2
Gene Synonym:
Exon (10)1607..1630
Gene:GABRG2
Gene Synonym:
Exon (11)1631..4077
Gene:GABRG2
Gene Synonym:
Translation
Position Chain Variation Link
1 1 -, gtaa dbSNP:781608673
1 1 a, g dbSNP:535933351
5 5 a, g dbSNP:551085504
36 36 c, g dbSNP:373691169
77 77 c, t dbSNP:772816792
119 119 c, t dbSNP:114796537
140 140 a, g dbSNP:539867682
142 142 c, g dbSNP:748771306
150 150 c, t dbSNP:557868741
161 161 a, g dbSNP:573159939
179 179 a, g dbSNP:534235351
205 205 c, t dbSNP:3219203
213 213 a, g dbSNP:573923202
306 306 g, t dbSNP:541552445
313 313 c, t dbSNP:764214358
315 315 g, t dbSNP:367762747
320 320 a, c dbSNP:371508835
330 330 a, g dbSNP:757437605
334 334 c, g dbSNP:765592275
337 337 -, t dbSNP:36112889
337 337 a, g dbSNP:750851406
342 342 a, g dbSNP:758944561
342 342 -, g dbSNP:758313419
343 343 -, a, aa dbSNP:771282908
344 344 -, aaa dbSNP:781628762
344 344 -, aa dbSNP:777736322
344 344 -, a dbSNP:780201998
346 346 a, g dbSNP:780757403
349 349 a, g dbSNP:746505697
350 350 a, c dbSNP:754584418
358 358 a, g dbSNP:780572044
362 362 a, g dbSNP:747787220
365 365 c, t dbSNP:769362559
367 367 g, t dbSNP:55716248
369 369 a, c, t dbSNP:375295110
371 371 a, t dbSNP:774337016
375 375 c, t dbSNP:759392289
379 379 c, g dbSNP:764172866
382 382 a, c dbSNP:183259247
394 394 a, t dbSNP:762058667
399 399 a, g dbSNP:61750979
402 402 c, g dbSNP:750798004
410 410 c, g dbSNP:141106898
412 412 a, g dbSNP:200838780
436 436 a, g dbSNP:564088820
437 437 a, g dbSNP:766990192
446 446 -, ctg dbSNP:770106632
448 448 g, t dbSNP:115976622
457 457 c, t dbSNP:368162707
460 460 c, t dbSNP:780713471
461 461 c, t dbSNP:747649928
467 467 g, t dbSNP:753427115
480 480 a, c dbSNP:756921875
484 484 -, tga dbSNP:769160013
493 493 c, t dbSNP:375308385
496 496 c, t dbSNP:745694203
502 502 a, t dbSNP:772026488
505 505 g, t dbSNP:779917631
520 520 a, g dbSNP:748255945
521 521 -, g dbSNP:35315145
524 524 a, g dbSNP:530774170
529 529 g, t dbSNP:368962609
531 531 a, c dbSNP:763218917
543 543 c, t dbSNP:771317794
547 547 g, t dbSNP:774756037
548 548 a, g dbSNP:759874474
574 574 a, c dbSNP:768062008
576 576 c, t dbSNP:112586362
577 577 a, g dbSNP:753076158
594 594 a, g dbSNP:112894280
601 601 a, t dbSNP:143295869
602 602 c, t dbSNP:146470870
603 603 a, g dbSNP:121909673
604 604 a, g dbSNP:763542378
605 605 c, t dbSNP:587777365
614 614 a, g dbSNP:753381913
628 628 a, g dbSNP:758084555
638 638 a, g dbSNP:766039298
650 650 c, g dbSNP:751432250
653 653 a, c dbSNP:758970487
673 673 c, t dbSNP:11135176
691 691 c, t dbSNP:777192588
692 692 a, g dbSNP:111782778
694 694 a, t dbSNP:370890791
699 699 a, g dbSNP:764596401
709 709 g, t dbSNP:76898315
711 711 c, t dbSNP:772800839
712 712 a, g dbSNP:61735412
716 716 a, t dbSNP:766103158
718 718 a, g dbSNP:77298346
730 730 a, t dbSNP:754884716
733 733 c, t dbSNP:767423340
752 752 a, g dbSNP:752621588
760 760 c, g dbSNP:562384157
761 761 c, t dbSNP:74930063
765 765 a, g dbSNP:778814579
767 767 c, t dbSNP:200828542
782 782 a, g dbSNP:758530172
783 783 g, t dbSNP:780317346
786 786 a, g dbSNP:747372679
793 793 c, t dbSNP:768946471
799 799 c, t dbSNP:781551591
822 822 c, t dbSNP:267600531
825 825 a, g dbSNP:748607809
828 828 a, c dbSNP:770364855
839 839 c, t dbSNP:772566750
866 866 c, t dbSNP:762581269
883 883 c, t dbSNP:770485021
887 887 c, g dbSNP:267606837
910 910 a, g dbSNP:758574181
928 928 c, t dbSNP:564464466
937 937 a, g dbSNP:751723547
938 938 c, t dbSNP:755215653
940 940 a, g dbSNP:781498456
943 943 c, t dbSNP:150134470
946 946 c, t dbSNP:211037
952 952 a, g dbSNP:778408584
953 953 a, g dbSNP:749764060
954 954 a, t dbSNP:770506471
964 964 a, c dbSNP:774016949
967 967 c, t dbSNP:759221112
970 970 c, t dbSNP:771888226
985 985 a, c dbSNP:17855004
996 996 a, g dbSNP:757866706
1001 1001 a, g dbSNP:211035
1009 1009 a, g dbSNP:568361993
1022 1022 a, g dbSNP:745417603
1036 1036 at, gg dbSNP:386694324
1036 1036 a, g, t dbSNP:143065876
1037 1037 g, t dbSNP:148215078
1042 1042 c, g, t dbSNP:191391831
1053 1053 a, g dbSNP:776313428
1061 1061 g, t dbSNP:41311629
1063 1063 a, c dbSNP:114972096
1076 1076 c, g dbSNP:774394343
1091 1091 a, c dbSNP:759678544
1098 1098 c, t dbSNP:377438322
1102 1102 g, t dbSNP:760385319
1111 1111 a, t dbSNP:779447500
1121 1121 c, t dbSNP:746626989
1133 1133 a, g dbSNP:768224402
1149 1149 a, g dbSNP:776456366
1168 1168 a, c, t dbSNP:747988447
1169 1169 a, g dbSNP:773065895
1180 1180 c, t dbSNP:762889745
1195 1195 a, g dbSNP:78261481
1196 1196 a, t dbSNP:52792201
1216 1216 a, g dbSNP:775462510
1222 1222 c, t dbSNP:760916801
1226 1226 a, g dbSNP:549251133
1231 1231 a, c dbSNP:764267675
1237 1237 a, g dbSNP:202124575
1246 1246 c, t dbSNP:201672465
1267 1267 g, t dbSNP:754514348
1272 1272 a, g dbSNP:780766516
1276 1276 c, t dbSNP:115126975
1288 1288 a, g dbSNP:200449368
1318 1318 c, t dbSNP:558779533
1321 1321 a, c dbSNP:749127891
1333 1333 c, t dbSNP:770884037
1339 1339 c, g, t dbSNP:778780107
1340 1340 a, g dbSNP:768565280
1342 1342 c, t dbSNP:372757018
1369 1369 c, t dbSNP:776876970
1377 1377 c, t dbSNP:543339576
1420 1420 a, g dbSNP:377502016
1432 1432 c, t dbSNP:749531013
1439 1439 a, g dbSNP:763639081
1446 1446 a, g dbSNP:397514737
1450 1450 a, g dbSNP:369614121
1453 1453 a, g dbSNP:774809218
1456 1456 c, t dbSNP:373993626
1461 1461 a, t dbSNP:121909672
1463 1463 g, t dbSNP:768061156
1465 1465 a, c dbSNP:774964109
1474 1474 c, t dbSNP:138964417
1477 1477 a, t dbSNP:377638785
1478 1478 a, g dbSNP:398123523
1480 1480 a, g dbSNP:371601817
1495 1495 a, t dbSNP:753372205
1523 1523 a, g dbSNP:756959300
1531 1531 a, g dbSNP:149472714
1548 1548 a, g dbSNP:17855003
1555 1555 c, t dbSNP:750277181
1565 1565 c, t dbSNP:374512652
1566 1566 a, g dbSNP:780199000
1571 1571 c, t dbSNP:377035112
1588 1588 a, t dbSNP:201824364
1589 1589 -, aaa dbSNP:749611954
1591 1591 -, aaa dbSNP:727503941
1597 1597 a, g dbSNP:571034662
1600 1600 a, g dbSNP:776166431
1609 1609 g, t dbSNP:780368645
1613 1613 c, t dbSNP:747426141
1614 1614 a, g dbSNP:755430911
1619 1619 c, t dbSNP:199574539
1621 1621 g, t dbSNP:781756750
1623 1623 c, t dbSNP:267600532
1631 1631 c, g dbSNP:2229946
1634 1634 c, t dbSNP:757311213
1649 1649 c, t dbSNP:768576864
1650 1650 a, g dbSNP:528036202
1651 1651 c, g dbSNP:761755629
1657 1657 a, t dbSNP:770952397
1658 1658 c, t dbSNP:774328514
1664 1664 a, g dbSNP:759779386
1667 1667 a, g dbSNP:375785093
1670 1670 c, t dbSNP:121909674
1673 1673 a, g dbSNP:753097258
1680 1680 a, t dbSNP:778999273
1682 1682 a, g, t dbSNP:143945240
1685 1685 a, g dbSNP:757868774
1697 1697 a, g dbSNP:778533443
1714 1714 c, t dbSNP:749951528
1732 1732 c, t dbSNP:113085352
1733 1733 a, g dbSNP:148232491
1734 1734 a, g dbSNP:746678010
1749 1749 a, g dbSNP:369200303
1751 1751 g, t dbSNP:780991820
1753 1753 c, t dbSNP:748041632
1762 1762 c, t dbSNP:141138508
1776 1776 a, g dbSNP:774474550
1784 1784 a, g dbSNP:759598497
1794 1794 a, t dbSNP:772194057
1798 1798 a, g dbSNP:150727562
1799 1799 a, g dbSNP:761000541
1804 1804 a, g dbSNP:760834360
1812 1812 g, t dbSNP:587780341
1814 1814 a, g dbSNP:764513577
1828 1828 c, t dbSNP:202246006
1834 1834 c, t dbSNP:762386331
1867 1867 a, g dbSNP:765904792
1881 1881 a, g dbSNP:749946230
1889 1889 c, t dbSNP:757781259
1891 1891 c, t dbSNP:765926862
1907 1907 a, g dbSNP:751127136
1917 1917 a, g dbSNP:754658882
1921 1921 c, t dbSNP:780936760
1929 1929 c, t dbSNP:747992571
1931 1931 a, g dbSNP:756037476
1936 1936 c, t dbSNP:777501290
1938 1938 c, t dbSNP:749257839
1946 1946 c, g dbSNP:771995505
1947 1947 c, t dbSNP:373649929
1948 1948 c, t dbSNP:747202413
1949 1949 c, t dbSNP:769046548
1951 1951 a, t dbSNP:777124332
1952 1952 a, t dbSNP:762335640
1953 1953 -, agagactgagagtctcact dbSNP:775151354
1953 1953 a, g dbSNP:765639964
1955 1955 -, gagatgtctgt dbSNP:762872104
1957 1957 a, g dbSNP:370402998
1991 1991 -, ta dbSNP:771639644
2007 2007 a, g dbSNP:750904065
2023 2023 a, c dbSNP:187224842
2043 2043 g, t dbSNP:145318600
2099 2099 c, t dbSNP:539963242
2100 2100 a, g dbSNP:758832535
2121 2121 a, c dbSNP:558250245
2153 2153 c, t dbSNP:371389067
2167 2167 a, g dbSNP:148001179
2195 2195 a, t dbSNP:769488331
2219 2219 a, t dbSNP:534139912
2249 2249 a, g dbSNP:41275341
2254 2254 a, g dbSNP:192973258
2280 2280 a, g dbSNP:573126853
2290 2290 c, t dbSNP:773854777
2291 2291 a, g dbSNP:185169107
2294 2294 c, t dbSNP:759550610
2316 2316 c, g dbSNP:556737874
2328 2328 c, t dbSNP:752382943
2342 2342 a, g dbSNP:3180569
2347 2347 a, c, t dbSNP:188825588
2423 2423 c, g dbSNP:563791011
2456 2456 -, aataacttagaat dbSNP:769280685
2457 2457 a, g dbSNP:528169677
2461 2461 a, c dbSNP:193024691
2489 2489 a, g dbSNP:556132977
2496 2496 c, t dbSNP:540625537
2515 2515 c, t dbSNP:418210
2550 2550 c, t dbSNP:532694990
2559 2559 a, g dbSNP:550574038
2567 2567 a, t dbSNP:424740
2604 2604 a, g dbSNP:563105218
2624 2624 c, g dbSNP:762034001
2630 2630 c, g dbSNP:765232468
2648 2648 c, t dbSNP:367757836
2649 2649 a, g dbSNP:116673668
2672 2672 a, t dbSNP:750509121
2700 2700 a, g dbSNP:73316347
2703 2703 g, t dbSNP:118064447
2747 2747 a, t dbSNP:371240534
2782 2782 a, g dbSNP:758965402
2809 2809 c, t dbSNP:534017024
2834 2834 -, a dbSNP:756746053
2853 2853 a, g dbSNP:766852844
2908 2908 a, g dbSNP:555757475
2922 2922 g, t dbSNP:567521884
2951 2951 a, g dbSNP:41304898
2972 2972 a, t dbSNP:538544011
2976 2976 a, g dbSNP:375311334
2996 2996 c, t dbSNP:751962818
3030 3030 g, t dbSNP:755370766
3069 3069 c, t dbSNP:556537352
3086 3086 c, t dbSNP:577817884
3099 3099 c, t dbSNP:184725064
3148 3148 a, t dbSNP:553936990
3175 3175 c, t dbSNP:781573317
3205 3205 a, g dbSNP:572636789
3264 3264 g, t dbSNP:530406856
3306 3306 c, t dbSNP:539929585
3307 3307 c, t dbSNP:780622182
3313 3313 a, t dbSNP:748908802
3333 3333 c, t dbSNP:375013278
3334 3334 a, g dbSNP:367974933
3335 3335 -, a dbSNP:34809383
3348 3348 a, g dbSNP:111695377
3374 3374 a, g dbSNP:372041761
3396 3396 g, t dbSNP:553454795
3399 3399 g, t dbSNP:548569193
3403 3403 c, t dbSNP:11956247
3422 3422 a, c, g dbSNP:745348234
3424 3424 a, g dbSNP:567153845
3430 3430 c, t dbSNP:746892139
3441 3441 c, t dbSNP:533511123
3447 3447 a, t dbSNP:562728260
3456 3456 a, g dbSNP:578039218
3484 3484 a, g dbSNP:545350783
3507 3507 c, t dbSNP:768346662
3542 3542 c, t dbSNP:551794496
3564 3564 c, g dbSNP:570208308
3566 3566 c, g dbSNP:755680345
3591 3591 c, t dbSNP:557096441
3614 3614 c, t dbSNP:188046779
3616 3616 a, g dbSNP:566646982
3621 3621 c, g dbSNP:376466092
3754 3754 c, t dbSNP:762003732
3780 3780 c, t dbSNP:537576088
3800 3800 c, t dbSNP:779806977
3833 3833 a, c dbSNP:112419308
3841 3841 a, g dbSNP:765480194
3861 3861 g, t dbSNP:180905867
3873 3873 a, g dbSNP:748432555
3874 3874 g, t dbSNP:549173529
3880 3880 a, g dbSNP:150875037
3933 3933 a, c dbSNP:766408832
3988 3988 c, t dbSNP:752085538
3990 3990 c, t dbSNP:755422089
4001 4001 c, g dbSNP:138297122
4025 4025 -, at dbSNP:767716700
4026 4026 -, at dbSNP:34705786
4027 4027 c, t dbSNP:200339735
4053 4053 c, t dbSNP:183746824
4070 4070 a, g dbSNP:189481479

Target ORF information:

RefSeq Version NM_198903
Organism Homo sapiens (human)
Definition Homo sapiens gamma-aminobutyric acid (GABA) A receptor, gamma 2 (GABRG2), transcript variant 3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_198903

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGAGTTCGC CAAATATATG GAGCACAGGA AGCTCAGTCT ACTCGACTCC TGTATTTTCA 
CAGAAAATGA CGGTGTGGAT TCTGCTCCTG CTGTCGCTCT ACCCTGGCTT CACTAGCCAG
AAATCTGATG ATGACTATGA AGATTATGCT TCTAACAAAA CATGGGTCTT GACTCCAAAA
GTTCCTGAGG GTGATGTCAC TGTCATCTTA AACAACCTGC TGGAAGGATA TGACAATAAA
CTTCGGCCTG ATATAGGAGT GAAGCCAACG TTAATTCACA CAGACATGTA TGTGAATAGC
ATTGGTCCAG TGAACGCTAT CAATATGGAA TACACTATTG ATATATTTTT TGCGCAAACG
TGGTATGACA GACGTTTGAA ATTTAACAGC ACCATTAAAG TCCTCCGATT GAACAGCAAC
ATGGTGGGGA AAATCTGGAT TCCAGACACT TTCTTCAGAA ATTCCAAAAA AGCTGATGCA
CACTGGATCA CCACCCCCAA CAGGATGCTG AGAATTTGGA ATGATGGTCG AGTGCTCTAC
ACCCTAAGGT TGACAATTGA TGCTGAGTGC CAATTACAAT TGCACAACTT TCCAATGGAT
GAACACTCCT GCCCCTTGGA GTTCTCCAGT TGGTCTCGTT CTATTGCCCA GGCTGGAATG
TGCAGTGGTG TGATCTCGGC TCACTACAGC CTTCGCTTCT GGGGCTCAAC TGATCCTCCC
ACCTTGGCCT CCAGAGTAGC TGGGATTTCA GATGGCTATC CACGTGAAGA AATTGTTTAT
CAATGGAAGC GAAGTTCTGT TGAAGTGGGC GACACAAGAT CCTGGAGGCT TTATCAATTC
TCATTTGTTG GTCTAAGAAA TACCACCGAA GTAGTGAAGA CAACTTCCGG AGATTATGTG
GTCATGTCTG TCTACTTTGA TCTGAGCAGA AGAATGGGAT ACTTTACCAT CCAGACCTAT
ATCCCCTGCA CACTCATTGT CGTCCTATCC TGGGTGTCTT TCTGGATCAA TAAGGATGCT
GTTCCAGCCA GAACATCTTT AGGTATCACC ACTGTCCTGA CAATGACCAC CCTCAGCACC
ATTGCCCGGA AATCGCTCCC CAAGGTCTCC TATGTCACAG CGATGGATCT CTTTGTATCT
GTTTGTTTCA TCTTTGTCTT CTCTGCTCTG GTGGAGTATG GCACCTTGCA TTATTTTGTC
AGCAACCGGA AACCAAGCAA GGACAAAGAT AAAAAGAAGA AAAACCCTCT TCTTCGGATG
TTTTCCTTCA AGGCCCCTAC CATTGATATC CGCCCAAGAT CAGCAACCAT TCAAATGAAT
AATGCTACAC ACCTTCAAGA GAGAGATGAA GAGTACGGCT ATGAGTGTCT GGACGGCAAG
GACTGTGCCA GTTTTTTCTG CTGTTTTGAA GATTGTCGAA CAGGAGCTTG GAGACATGGG
AGGATACATA TCCGCATTGC CAAAATGGAC TCCTATGCTC GGATCTTCTT CCCCACTGCC
TTCTGCCTGT TTAATCTGGT CTATTGGGTC TCCTACCTCT ACCTGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.