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GALR1 galanin receptor 1 [Homo sapiens (human)]

Gene Symbol GALR1
Entrez Gene ID 2587
Full Name galanin receptor 1
Synonyms GALNR, GALNR1
General protein information
Preferred Names
galanin receptor type 1
Names
galanin receptor type 1
GAL1-R
GALR-1
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

18

18q23

Summary The neuropeptide galanin elicits a range of biological effects by interaction with specific G-protein-coupled receptors. Galanin receptors are seven-transmembrane proteins shown to activate a variety of intracellular second-messenger pathways. GALR1 inhibits adenylyl cyclase via a G protein of the Gi/Go family. GALR1 is widely expressed in the brain and spinal cord, as well as in peripheral sites such as the small intestine and heart. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

600377

Disorder Html:





The following GALR1 gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GALR1 gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu17969 NM_001480 Homo sapiens galanin receptor 1 (GALR1), mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $289

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu17969
Accession Version NM_001480.3
Sequence Information ORF Nucleotide Sequence (Length: 1050bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product galanin receptor type 1
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC100863.2 and U23854.1. This sequence is a reference standard in the RefSeqGene project. On Feb 6, 2008 this sequence version replaced gi:6031165. Summary: The neuropeptide galanin elicits a range of biological effects by interaction with specific G-protein-coupled receptors. Galanin receptors are seven-transmembrane proteins shown to activate a variety of intracellular second-messenger pathways. GALR1 inhibits adenylyl cyclase via a G protein of the Gi/Go family. GALR1 is widely expressed in the brain and spinal cord, as well as in peripheral sites such as the small intestine and heart. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC095530.1, L34339.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2142348 [ECO:0000348] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGGAGCTGG CGGTCGGGAA CCTCAGCGAG GGCAACGCGA GCTGGCCGGA GCCCCCCGCC 
CCGGAGCCCG GGCCGCTGTT CGGCATCGGC GTGGAGAACT TCGTCACGCT GGTGGTGTTC
GGCCTGATCT TCGCGCTGGG TGTGCTGGGC AACAGCCTAG TGATCACCGT GCTGGCGCGC
AGCAAGCCGG GCAAGCCGCG GAGCACCACC AACCTGTTCA TCCTCAACCT GAGCATCGCC
GACCTGGCCT ACCTGCTCTT CTGCATCCCC TTCCAGGCCA CCGTGTACGC GCTGCCCACC
TGGGTGCTGG GCGCCTTCAT CTGCAAGTTC ATCCACTACT TCTTCACCGT GTCCATGCTG
GTGAGCATCT TCACCCTGGC CGCGATGTCC GTGGACCGCT ACGTGGCCAT CGTGCACTCG
CGGCGCTCCT CCTCCCTCAG GGTGTCCCGC AACGCGCTGC TGGGCGTGGG CTGCATCTGG
GCGCTGTCCA TTGCCATGGC CTCGCCCGTG GCCTACCACC AGGGCCTCTT CCACCCGCGC
GCCAGCAACC AGACCTTCTG CTGGGAGCAG TGGCCCGACC CTCGCCACAA GAAGGCCTAC
GTGGTGTGCA CCTTCGTCTT CGGCTACCTG CTGCCGCTCC TGCTCATCTG CTTCTGCTAT
GCCAAGGTCC TTAATCACTT GCATAAAAAG TTGAAGAACA TGTCAAAGAA GTCTGAAGCA
TCCAAGAAAA AGACTGCACA GACAGTTCTG GTGGTGGTTG TGGTGTTTGG AATCTCCTGG
CTGCCGCACC ACATCATCCA TCTCTGGGCT GAGTTTGGAG TTTTCCCGCT GACGCCGGCT
TCCTTCCTCT TCAGAATCAC CGCCCACTGC CTGGCGTACA GCAATTCCTC CGTGAATCCT
ATCATTTATG CATTTCTCTC TGAAAATTTC AGGAAGGCCT ATAAACAAGT GTTCAAGTGT
CACATTCGCA AAGATTCACA CCTGAGTGAT ACTAAAGAAA GTAAAAGTCG AATAGACACC
CCACCATCAA CCAATTGTAC TCATGTGTGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_001471.2
CDS498..1547
Misc Feature(1)606..668(+)
Misc Feature(2)666..1406(+)
Misc Feature(3)708..770(+)
Misc Feature(4)825..890(+)
Misc Feature(5)951..1013(+)
Misc Feature(6)1098..1160(+)
Misc Feature(7)1242..1304(+)
Misc Feature(8)1311..1373(+)
Exon (1)1..1163
Gene:GALR1
Gene Synonym:
Exon (2)1164..1229
Gene:GALR1
Gene Synonym:
Exon (3)1230..2787
Gene:GALR1
Gene Synonym:
Translation
Position Chain Variation Link
36 36 c, g dbSNP:749587235
72 72 a, g dbSNP:555014238
76 76 -, c dbSNP:370287320
76 76 c, g dbSNP:5371
78 78 c, g dbSNP:5372
85 85 a, g dbSNP:557416889
88 88 c, t dbSNP:577052545
113 113 c, t dbSNP:372600119
136 136 c, g dbSNP:560013590
153 153 c, g dbSNP:112698072
200 200 g, t dbSNP:528739386
217 217 a, c dbSNP:13306374
243 243 a, g dbSNP:763478271
291 291 c, t dbSNP:776267464
304 304 c, g dbSNP:5373
318 318 g, t dbSNP:552466936
323 323 a, g dbSNP:536759138
326 326 a, t dbSNP:765206500
329 329 c, g dbSNP:548735742
339 339 a, g dbSNP:374694586
391 391 g, t dbSNP:570928671
393 393 a, g dbSNP:533177283
420 420 c, t dbSNP:546436509
435 435 c, t dbSNP:12955673
440 440 a, g dbSNP:13306375
442 442 c, t dbSNP:376635516
443 443 a, g dbSNP:535428789
458 458 c, t dbSNP:537708873
459 459 c, t dbSNP:549249793
461 461 a, g dbSNP:752037909
467 467 a, c dbSNP:142660460
468 468 c, g dbSNP:375230135
498 498 a, t dbSNP:745879242
501 501 c, g dbSNP:377602612
519 519 c, t dbSNP:201461949
527 527 a, g dbSNP:780407897
528 528 a, g dbSNP:749141409
532 532 a, g dbSNP:768301664
533 533 c, g dbSNP:755295011
539 539 c, t dbSNP:761678726
542 542 g, t dbSNP:1143093
544 544 a, c, t dbSNP:577285257
546 546 c, g dbSNP:760167095
548 548 -, c dbSNP:758903262
549 549 c, t dbSNP:539654659
551 551 c, t dbSNP:753457954
555 555 a, g dbSNP:759188587
555 555 -, g dbSNP:764498666
556 556 a, c, t dbSNP:200473944
557 557 c, t dbSNP:757711998
558 558 c, t dbSNP:781764050
563 563 c, g dbSNP:750585637
569 569 a, g dbSNP:565505361
573 573 a, c, g dbSNP:780459288
575 575 c, g dbSNP:768873733
576 576 c, g, t dbSNP:778585624
587 587 c, g dbSNP:771968617
603 603 a, g, t dbSNP:773113027
604 604 a, c dbSNP:770459715
609 609 g, t dbSNP:776070702
612 612 a, g dbSNP:759127851
617 617 c, t dbSNP:764880864
618 618 a, g dbSNP:774648296
622 622 c, t dbSNP:762227529
629 629 a, c, g, t dbSNP:768184332
632 632 g, t dbSNP:766584535
633 633 c, t dbSNP:753897070
635 635 a, g dbSNP:142421033
638 638 c, t dbSNP:5374
653 653 c, t dbSNP:368175092
658 658 c, t dbSNP:758160503
658 658 -, t dbSNP:752160814
665 665 c, t dbSNP:777504901
675 675 c, t dbSNP:746972199
676 676 a, g, t dbSNP:770801123
684 684 c, t dbSNP:745382350
685 685 c, g, t dbSNP:372334570
686 686 a, g dbSNP:762122328
691 691 -, gcc dbSNP:755550070
696 696 a, c dbSNP:768020884
699 699 a, g dbSNP:773659616
700 700 a, c, g dbSNP:188067960
703 703 a, c, t dbSNP:753930579
706 706 c, t dbSNP:765419205
713 713 c, g dbSNP:752996825
717 717 a, t dbSNP:758567691
722 722 c, t dbSNP:376456092
727 727 c, t dbSNP:746743654
735 735 a, g, t dbSNP:191309779
737 737 a, c dbSNP:374729499
738 738 a, g dbSNP:745422581
741 741 c, t dbSNP:769313107
748 748 a, c dbSNP:779389378
753 753 c, g, t dbSNP:748966690
759 759 c, t dbSNP:773715031
762 762 a, g dbSNP:761116963
765 765 c, t dbSNP:771622194
767 767 c, t dbSNP:777171908
775 775 a, c dbSNP:759923285
779 779 c, t dbSNP:765381789
787 787 c, t dbSNP:140216881
801 801 a, g dbSNP:763170392
803 803 a, g, t dbSNP:5375
805 805 c, t dbSNP:371377239
807 807 c, g dbSNP:137888300
810 810 a, g dbSNP:781027981
820 820 c, g dbSNP:750403901
836 836 c, t dbSNP:564578265
845 845 c, t dbSNP:779626434
852 852 a, g dbSNP:748739686
854 854 c, g dbSNP:768489000
862 862 a, g dbSNP:375738027
863 863 c, t dbSNP:747425503
871 871 a, c, t dbSNP:778211157
878 878 a, c, t dbSNP:201900969
880 880 c, g dbSNP:775709436
894 894 c, g dbSNP:763012311
899 899 c, t dbSNP:372144169
908 908 c, t dbSNP:751752274
909 909 c, g dbSNP:375468486
912 912 a, c dbSNP:767364713
919 919 g, t dbSNP:750124416
922 922 a, g dbSNP:756079511
923 923 c, t dbSNP:560128923
929 929 c, t dbSNP:753457111
931 931 a, c dbSNP:754513356
945 945 c, g dbSNP:141065471
962 962 a, c dbSNP:747827414
963 963 a, g dbSNP:144878705
967 967 c, g, t dbSNP:369466208
968 968 a, c dbSNP:770393593
974 974 c, g dbSNP:552581288
980 980 g, t dbSNP:775956222
992 992 a, c, t dbSNP:138670052
997 997 c, t dbSNP:774363658
998 998 c, t dbSNP:139443605
1001 1001 a, g dbSNP:149293813
1005 1005 a, g dbSNP:773124766
1009 1009 c, t dbSNP:150987448
1016 1016 c, g dbSNP:766387396
1022 1022 c, t dbSNP:753795821
1032 1032 a, c dbSNP:754915181
1035 1035 a, c dbSNP:764853182
1040 1040 c, g dbSNP:752190390
1041 1041 a, g dbSNP:537464599
1052 1052 -, ctt dbSNP:779579416
1066 1066 a, g dbSNP:777281036
1069 1069 a, g dbSNP:746295596
1071 1071 a, c dbSNP:756406904
1076 1076 c, g dbSNP:780360383
1080 1080 c, g, t dbSNP:144563998
1085 1085 c, g dbSNP:373267263
1087 1087 a, g dbSNP:774817709
1097 1097 c, g dbSNP:376472395
1099 1099 c, t dbSNP:200378187
1106 1106 c, t dbSNP:773282046
1108 1108 -, ca dbSNP:748820545
1110 1110 g, t dbSNP:760558139
1112 1112 a, c dbSNP:766307458
1118 1118 c, t dbSNP:776511871
1124 1124 c, t dbSNP:571015104
1127 1127 a, g dbSNP:533699524
1152 1152 g, t dbSNP:765263707
1153 1153 g, t dbSNP:752313924
1156 1156 a, g, t dbSNP:757826583
1164 1164 g, t dbSNP:148318041
1172 1172 -, t dbSNP:778542239
1174 1174 a, c dbSNP:769746945
1198 1198 g, t dbSNP:148677424
1206 1206 a, c dbSNP:762807305
1217 1217 a, c dbSNP:768567188
1222 1222 a, g dbSNP:200111121
1223 1223 a, g dbSNP:761295738
1236 1236 c, t dbSNP:566872227
1237 1237 a, g, t dbSNP:143127587
1242 1242 a, g dbSNP:142216832
1244 1244 c, t dbSNP:766051829
1245 1245 c, g dbSNP:376047000
1251 1251 g, t dbSNP:763357156
1255 1255 c, t dbSNP:764549800
1266 1266 g, t dbSNP:76465215
1273 1273 a, c dbSNP:752145542
1282 1282 c, t dbSNP:757793359
1283 1283 a, c, g dbSNP:767721887
1284 1284 c, t dbSNP:756353644
1290 1290 a, t dbSNP:77169818
1305 1305 a, g dbSNP:749083410
1309 1309 a, c dbSNP:147418211
1312 1312 c, t dbSNP:202045915
1323 1323 c, t dbSNP:748105208
1325 1325 a, c, g, t dbSNP:150691081
1328 1328 a, g dbSNP:770540051
1329 1329 a, t dbSNP:539586255
1330 1330 c, t dbSNP:377752132
1331 1331 a, g dbSNP:776318304
1332 1332 c, t dbSNP:759072847
1333 1333 c, t dbSNP:140013561
1334 1334 a, g dbSNP:139812601
1335 1335 g, t dbSNP:762419119
1339 1339 c, t dbSNP:267605260
1352 1352 a, c dbSNP:768129249
1357 1357 c, t dbSNP:750585389
1358 1358 c, t dbSNP:557561459
1359 1359 a, g dbSNP:149816752
1361 1361 c, t dbSNP:754119122
1362 1362 c, t dbSNP:755105594
1368 1368 a, c dbSNP:778691702
1373 1373 a, g dbSNP:199730182
1376 1376 c, g, t dbSNP:758387946
1377 1377 a, g dbSNP:777666336
1381 1381 a, g dbSNP:201229811
1385 1385 c, t dbSNP:376957505
1388 1388 c, t dbSNP:780521070
1389 1389 a, g dbSNP:745551553
1396 1396 c, g dbSNP:371953398
1409 1409 a, c dbSNP:769268550
1414 1414 g, t dbSNP:774918810
1428 1428 a, c dbSNP:771160406
1429 1429 g, t dbSNP:762251608
1433 1433 c, g dbSNP:772751317
1434 1434 a, g dbSNP:145820336
1447 1447 g, t dbSNP:773821311
1457 1457 -, tcaca dbSNP:746799506
1458 1458 c, t dbSNP:553756626
1460 1460 c, t dbSNP:766501938
1464 1464 a, c, t dbSNP:753801878
1465 1465 a, g dbSNP:765432250
1489 1489 c, t dbSNP:774695515
1498 1498 a, g dbSNP:5376
1504 1504 c, g dbSNP:777506870
1506 1506 c, t dbSNP:374047751
1510 1510 c, t dbSNP:757088730
1518 1518 a, c dbSNP:113010483
1522 1522 c, t dbSNP:5377
1531 1531 a, g dbSNP:745369709
1534 1534 a, g dbSNP:369126559
1541 1541 a, t dbSNP:779826907
1544 1544 a, g dbSNP:748559973
1551 1551 a, t dbSNP:373846302
1553 1553 a, g dbSNP:773398427
1555 1555 c, t dbSNP:761257157
1556 1556 a, g dbSNP:771275729
1559 1559 g, t dbSNP:776837217
1560 1560 c, t dbSNP:759512675
1566 1566 g, t dbSNP:377700030
1568 1568 a, t dbSNP:775722901
1571 1571 c, g, t dbSNP:201172922
1579 1579 c, t dbSNP:531351765
1581 1581 a, g dbSNP:757290716
1583 1583 a, g dbSNP:767338851
1588 1588 c, t dbSNP:5378
1590 1590 a, g dbSNP:372077517
1591 1591 a, g dbSNP:755651870
1598 1598 a, g dbSNP:779669315
1606 1606 a, c dbSNP:75625493
1613 1613 a, g dbSNP:533528586
1618 1618 c, g dbSNP:5379
1642 1642 g, t dbSNP:775977228
1645 1645 c, g dbSNP:567014780
1682 1682 a, g dbSNP:112633832
1723 1723 g, t dbSNP:5380
1738 1738 c, t dbSNP:529584345
1752 1752 c, t dbSNP:549159168
1776 1776 a, c dbSNP:761040167
1798 1798 c, t dbSNP:569215709
1827 1827 c, g dbSNP:537983371
1847 1847 a, g dbSNP:549487946
1850 1850 c, t dbSNP:5381
1918 1918 a, c dbSNP:571132751
1931 1931 -, a dbSNP:5826511
1931 1931 a, g dbSNP:202067538
1942 1942 a, t dbSNP:77035445
1987 1987 c, t dbSNP:536626430
2000 2000 a, g dbSNP:5382
2057 2057 a, g dbSNP:554043494
2063 2063 a, g dbSNP:188062878
2110 2110 c, t dbSNP:542903961
2120 2120 c, t dbSNP:576501905
2121 2121 a, g dbSNP:144043696
2151 2151 a, g dbSNP:768479103
2160 2160 a, g dbSNP:576089236
2182 2182 a, g dbSNP:545138601
2198 2198 a, c dbSNP:150956443
2211 2211 a, g dbSNP:765955502
2255 2255 c, t dbSNP:139484006
2276 2276 a, g dbSNP:149662887
2322 2322 a, c dbSNP:755002340
2354 2354 c, t dbSNP:145654238
2385 2385 a, g dbSNP:767373193
2398 2398 a, t dbSNP:552706413
2413 2413 a, t dbSNP:141462310
2419 2419 c, t dbSNP:74327681
2427 2427 a, g dbSNP:562757463
2428 2428 c, t dbSNP:531571613
2429 2429 a, g dbSNP:542052069
2438 2438 a, g dbSNP:147001133
2446 2446 c, t dbSNP:749568360
2453 2453 a, g dbSNP:771116562
2501 2501 a, g dbSNP:147618117
2531 2531 a, g dbSNP:757250485
2532 2532 a, g dbSNP:191032659
2540 2540 a, c dbSNP:547322197
2546 2546 a, c dbSNP:567432206
2583 2583 c, t dbSNP:142123089
2667 2667 a, c dbSNP:556386388
2674 2674 a, g dbSNP:563411328
2729 2729 a, g dbSNP:779111661
2741 2741 c, t dbSNP:183139395
2782 2782 a, g dbSNP:538589787

Target ORF information:

RefSeq Version NM_001480
Organism Homo sapiens (human)
Definition Homo sapiens galanin receptor 1 (GALR1), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001480

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGGAGCTGG CGGTCGGGAA CCTCAGCGAG GGCAACGCGA GCTGGCCGGA GCCCCCCGCC 
CCGGAGCCCG GGCCGCTGTT CGGCATCGGC GTGGAGAACT TCGTCACGCT GGTGGTGTTC
GGCCTGATCT TCGCGCTGGG TGTGCTGGGC AACAGCCTAG TGATCACCGT GCTGGCGCGC
AGCAAGCCGG GCAAGCCGCG GAGCACCACC AACCTGTTCA TCCTCAACCT GAGCATCGCC
GACCTGGCCT ACCTGCTCTT CTGCATCCCC TTCCAGGCCA CCGTGTACGC GCTGCCCACC
TGGGTGCTGG GCGCCTTCAT CTGCAAGTTC ATCCACTACT TCTTCACCGT GTCCATGCTG
GTGAGCATCT TCACCCTGGC CGCGATGTCC GTGGACCGCT ACGTGGCCAT CGTGCACTCG
CGGCGCTCCT CCTCCCTCAG GGTGTCCCGC AACGCGCTGC TGGGCGTGGG CTGCATCTGG
GCGCTGTCCA TTGCCATGGC CTCGCCCGTG GCCTACCACC AGGGCCTCTT CCACCCGCGC
GCCAGCAACC AGACCTTCTG CTGGGAGCAG TGGCCCGACC CTCGCCACAA GAAGGCCTAC
GTGGTGTGCA CCTTCGTCTT CGGCTACCTG CTGCCGCTCC TGCTCATCTG CTTCTGCTAT
GCCAAGGTCC TTAATCACTT GCATAAAAAG TTGAAGAACA TGTCAAAGAA GTCTGAAGCA
TCCAAGAAAA AGACTGCACA GACAGTTCTG GTGGTGGTTG TGGTGTTTGG AATCTCCTGG
CTGCCGCACC ACATCATCCA TCTCTGGGCT GAGTTTGGAG TTTTCCCGCT GACGCCGGCT
TCCTTCCTCT TCAGAATCAC CGCCCACTGC CTGGCGTACA GCAATTCCTC CGTGAATCCT
ATCATTTATG CATTTCTCTC TGAAAATTTC AGGAAGGCCT ATAAACAAGT GTTCAAGTGT
CACATTCGCA AAGATTCACA CCTGAGTGAT ACTAAAGAAA GTAAAAGTCG AATAGACACC
CCACCATCAA CCAATTGTAC TCATGTGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.