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GEM GTP binding protein overexpressed in skeletal muscle [Homo sapiens (human)]

Gene Symbol GEM
Entrez Gene ID 2669
Full Name GTP binding protein overexpressed in skeletal muscle
Synonyms KIR
General protein information
Preferred Names
GTP-binding protein GEM
Names
GTP-binding protein GEM
RAS-like protein KIR
kinase-inducible Ras-like protein
GTP-binding mitogen-induced T-cell protein
GTP-binding protein overexpressed in skeletal muscle
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

8

8q13-q21

Summary The protein encoded by this gene belongs to the RAD/GEM family of GTP-binding proteins. It is associated with the inner face of the plasma membrane and could play a role as a regulatory protein in receptor-mediated signal transduction. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

600164

Disorder Html:





The following GEM gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GEM gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu01836 NM_005261 Homo sapiens GTP binding protein overexpressed in skeletal muscle (GEM), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$309
OHu01836 NM_181702 Homo sapiens GTP binding protein overexpressed in skeletal muscle (GEM), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$199

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu01836
Accession Version NM_005261.3
Sequence Information ORF Nucleotide Sequence (Length: 891bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product GTP-binding protein GEM
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB018783.1, BC022010.2 and AP003478.1. On Oct 6, 2009 this sequence version replaced gi:32483372. Summary: The protein encoded by this gene belongs to the RAD/GEM family of GTP-binding proteins. It is associated with the inner face of the plasma membrane and could play a role as a regulatory protein in receptor-mediated signal transduction. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]. Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U10550.1, AL549292.3 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA962346 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
ATGACTCTGA ATAATGTCAC CATGCGCCAG GGCACTGTGG GCATGCAGCC ACAGCAGCAG 
CGCTGGAGCA TCCCAGCTGA TGGCAGGCAT CTGATGGTCC AGAAAGAGCC CCACCAGTAC
AGCCACCGCA ACCGCCATTC TGCTACCCCT GAGGACCACT GCCGCCGAAG CTGGTCCTCT
GACTCCACAG ACTCAGTCAT CTCCTCTGAG TCAGGGAACA CCTACTACCG AGTGGTGCTC
ATAGGGGAGC AGGGGGTGGG CAAGTCCACT CTGGCCAACA TCTTTGCAGG TGTGCATGAC
AGCATGGACA GCGACTGCGA GGTGCTGGGA GAAGATACAT ATGAACGAAC CCTGATGGTT
GATGGGGAAA GTGCAACGAT TATACTCCTG GATATGTGGG AAAATAAGGG GGAAAATGAA
TGGCTCCATG ACCACTGCAT GCAGGTCGGG GACGCATACC TGATTGTCTA CTCAATCACA
GACCGAGCGA GCTTCGAGAA GGCATCTGAG CTGCGAATCC AGCTCCGCAG GGCCCGGCAG
ACAGAGGACA TTCCCATAAT TTTGGTTGGC AACAAAAGTG ACTTAGTGCG GTGCCGAGAA
GTGTCTGTAT CAGAAGGGAG AGCCTGTGCA GTGGTGTTTG ACTGCAAGTT CATCGAGACC
TCTGCAGCTG TCCAGCACAA CGTGAAGGAG CTGTTTGAGG GCATTGTGCG ACAGGTGCGC
CTTCGGCGGG ACAGCAAGGA GAAGAATGAA CGGCGGCTGG CCTACCAGAA AAGGAAGGAG
AGCATGCCCA GGAAAGCCAG GCGCTTCTGG GGCAAGATCG TGGCCAAAAA CAACAAGAAT
ATGGCCTTCA AGCTCAAGTC CAAATCCTGC CATGACCTCT CTGTACTCTA G
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_005252.1
CDS240..1130
Misc Feature(1)117..119(+)
Misc Feature(2)465..1127(+)
Misc Feature(3)468..959(+)
Misc Feature(4)483..506(+)
Misc Feature(5)486..641(+)
Misc Feature(6)489..905(+)
Misc Feature(7)504..908(+)
Misc Feature(8)552..584(+)
Misc Feature(9)552..581(+)
Misc Feature(10)558..560(+)
Misc Feature(11)630..641(+)
Misc Feature(12)636..695(+)
Misc Feature(13)810..821(+)
Misc Feature(14)900..908(+)
Misc Feature(15)1020..1022(+)
Misc Feature(16)1035..1094(+)
Misc Feature(17)1104..1106(+)
Misc Feature(18)1107..1118(+)
Exon (1)1..230
Gene:GEM
Gene Synonym:
Exon (2)231..570
Gene:GEM
Gene Synonym:
Exon (3)571..647
Gene:GEM
Gene Synonym:
Exon (4)648..852
Gene:GEM
Gene Synonym:
Exon (5)853..2187
Gene:GEM
Gene Synonym:
Translation
Position Chain Variation Link
15 15 a, g dbSNP:555106064
31 31 c, t dbSNP:535084384
42 42 c, g dbSNP:572301256
50 50 a, g dbSNP:781108102
65 65 c, g dbSNP:542397860
111 111 a, g dbSNP:755359530
122 122 c, g dbSNP:558443687
126 126 c, t dbSNP:751215218
128 128 a, g dbSNP:754716466
137 137 a, g dbSNP:766006457
167 167 a, c, t dbSNP:554305972
191 191 a, g dbSNP:2250208
206 206 g, t dbSNP:780074310
237 237 a, g dbSNP:771858021
244 244 c, t dbSNP:746033873
246 246 -, ct dbSNP:755082119
255 255 a, g dbSNP:779094271
259 259 c, t dbSNP:771211990
262 262 c, t dbSNP:374909426
264 264 c, t dbSNP:777960854
265 265 a, g dbSNP:756531627
271 271 a, c, g dbSNP:556308745
279 279 a, g dbSNP:542542829
280 280 a, g dbSNP:370415265
283 283 c, t dbSNP:34218332
285 285 c, t dbSNP:764949315
289 289 c, t dbSNP:761603767
297 297 c, t dbSNP:753235715
300 300 c, t dbSNP:140549853
305 305 g, t dbSNP:760461262
307 307 a, g dbSNP:775511173
317 317 c, t dbSNP:151310883
326 326 a, g dbSNP:759323238
327 327 c, t dbSNP:774173558
340 340 a, g dbSNP:771122242
343 343 a, t dbSNP:11539260
344 344 a, g dbSNP:749549314
347 347 a, g, t dbSNP:769925332
351 351 c, t dbSNP:35262320
355 355 a, g dbSNP:781762421
357 357 g, t dbSNP:755579538
365 365 c, g, t dbSNP:35065846
366 366 c, g, t dbSNP:2170363
368 368 c, t dbSNP:756928867
370 370 a, c, g dbSNP:763453975
372 372 -, cc dbSNP:144891099
372 372 a, c, t dbSNP:201351710
373 373 a, g dbSNP:17847126
383 383 c, t dbSNP:759521195
384 384 a, g dbSNP:774085906
385 385 c, t dbSNP:766195976
386 386 c, t dbSNP:763022208
387 387 c, t dbSNP:147133582
389 389 c, t dbSNP:769973168
398 398 c, t dbSNP:748224959
401 401 c, t dbSNP:776897188
402 402 c, t dbSNP:769234376
404 404 c, t dbSNP:747548067
406 406 a, g dbSNP:780498125
413 413 -, g dbSNP:774839596
415 415 c, t dbSNP:758803093
421 421 a, c dbSNP:746276333
422 422 c, g dbSNP:145616833
424 424 c, t dbSNP:755764047
434 434 a, g dbSNP:145046153
436 436 a, t dbSNP:767038807
443 443 -, ctc dbSNP:764523532
443 443 c, t dbSNP:780164919
445 445 c, g dbSNP:754873278
454 454 a, g dbSNP:751506282
458 458 c, t dbSNP:766109484
460 460 a, c dbSNP:762800000
463 463 a, g dbSNP:772917669
465 465 c, t dbSNP:765472126
468 468 c, t dbSNP:550393204
469 469 a, g dbSNP:761960990
473 473 c, g dbSNP:776810929
474 474 a, g dbSNP:768860314
476 476 a, g dbSNP:747460145
484 484 a, g dbSNP:776127220
488 488 a, g dbSNP:772521690
490 490 a, g dbSNP:201303048
492 492 c, g dbSNP:139494082
493 493 a, g dbSNP:567967510
502 502 a, g dbSNP:567771198
507 507 a, g dbSNP:747832501
509 509 g, t dbSNP:780616166
535 535 a, g dbSNP:754500839
542 542 -, catgg dbSNP:763246450
544 544 g, t dbSNP:751132195
549 549 a, t dbSNP:780005500
551 551 c, t dbSNP:758312817
552 552 a, g dbSNP:548062745
555 555 c, t dbSNP:764970254
556 556 a, g dbSNP:762025958
557 557 c, t dbSNP:754124324
558 558 a, g dbSNP:527705763
560 560 a, g dbSNP:201792479
576 576 a, g dbSNP:201677240
577 577 c, t dbSNP:757104245
585 585 c, t dbSNP:762667312
596 596 c, g dbSNP:764380913
597 597 c, g dbSNP:761027449
598 598 c, t dbSNP:530616234
604 604 a, g, t dbSNP:767526831
605 605 a, g dbSNP:773047264
612 612 a, g dbSNP:774736541
616 616 c, t dbSNP:184919570
617 617 a, g dbSNP:763307759
630 630 a, g dbSNP:773612061
649 649 a, g dbSNP:200005791
652 652 a, t dbSNP:751732240
653 653 a, g dbSNP:144483271
654 654 a, g dbSNP:763469017
679 679 c, t dbSNP:557922897
681 681 c, g dbSNP:773522304
686 686 a, c, t dbSNP:760261186
687 687 a, g dbSNP:774991627
692 692 c, t dbSNP:374944377
693 693 a, g dbSNP:372249284
705 705 c, g dbSNP:773969361
709 709 a, g dbSNP:770754951
712 712 c, g dbSNP:770933590
716 716 a, c dbSNP:554056106
722 722 c, t dbSNP:777669807
724 724 a, g dbSNP:149283301
727 727 c, t dbSNP:748020922
728 728 a, g dbSNP:762856348
734 734 c, t dbSNP:571339649
735 735 a, g dbSNP:781236754
741 741 a, c, g dbSNP:751539968
744 744 c, t dbSNP:766455469
752 752 a, g dbSNP:758865296
754 754 a, g dbSNP:750953687
760 760 a, c dbSNP:201731029
762 762 c, t dbSNP:762054664
765 765 c, t dbSNP:777120814
766 766 a, g, t dbSNP:759240105
767 767 c, t dbSNP:773931272
772 772 c, t dbSNP:770594268
774 774 c, t dbSNP:577912523
781 781 a, c dbSNP:74360159
794 794 c, t dbSNP:368254970
806 806 c, t dbSNP:769889864
808 808 c, g dbSNP:375183063
821 821 c, t dbSNP:762942878
828 828 c, t dbSNP:187593880
831 831 c, t dbSNP:558611127
834 834 c, t dbSNP:138582164
835 835 a, g dbSNP:780063278
846 846 a, g dbSNP:758453208
861 861 g, t dbSNP:778977780
869 869 a, g dbSNP:199789983
873 873 a, g dbSNP:754399008
893 893 c, g, t dbSNP:138012458
894 894 a, g dbSNP:753149152
898 898 a, c dbSNP:766122201
919 919 a, g dbSNP:762747900
921 921 a, g dbSNP:370285889
922 922 g, t dbSNP:764837790
926 926 a, g dbSNP:764235966
938 938 a, g dbSNP:761609378
941 941 c, g dbSNP:776610861
942 942 a, g dbSNP:141761903
948 948 a, c, t dbSNP:138147292
949 949 a, g dbSNP:368821999
954 954 a, g dbSNP:746095122
957 957 c, t dbSNP:190907564
958 958 a, g dbSNP:771063860
963 963 c, t dbSNP:749374110
966 966 c, t dbSNP:778310132
967 967 a, g dbSNP:200768882
968 968 g, t dbSNP:748506771
971 971 c, t dbSNP:781697524
978 978 a, g dbSNP:141202489
986 986 c, t dbSNP:750125754
990 990 c, t dbSNP:200775391
993 993 c, t dbSNP:138265181
994 994 a, g dbSNP:375369112
997 997 c, t dbSNP:764080201
999 999 g, t dbSNP:760620813
1001 1001 c, g dbSNP:775199448
1012 1012 g, t dbSNP:148957520
1017 1017 c, g dbSNP:759705261
1019 1019 c, g dbSNP:774608878
1020 1020 a, g dbSNP:771095990
1021 1021 a, g dbSNP:749379436
1023 1023 -, atgc dbSNP:746154399
1023 1023 a, g dbSNP:773218409
1025 1025 a, g dbSNP:770363121
1036 1036 c, t dbSNP:748700800
1037 1037 c, g dbSNP:551066990
1041 1041 c, t dbSNP:755375862
1042 1042 a, g dbSNP:145789382
1043 1043 c, t dbSNP:778625070
1052 1052 c, t dbSNP:530942518
1054 1054 a, g dbSNP:753332084
1058 1058 c, t dbSNP:201686704
1059 1059 a, g dbSNP:149831559
1072 1072 a, g dbSNP:752653844
1073 1073 a, c dbSNP:767490302
1076 1076 c, g dbSNP:759294461
1078 1078 a, c dbSNP:557181794
1084 1084 a, c dbSNP:372371105
1092 1092 c, t dbSNP:766608259
1094 1094 c, g dbSNP:142606096
1103 1103 a, g dbSNP:773272814
1104 1104 c, t dbSNP:770019011
1110 1110 c, t dbSNP:762037099
1111 1111 a, t dbSNP:777248979
1113 1113 g, t dbSNP:769356943
1119 1119 g, t dbSNP:747387622
1125 1125 c, t dbSNP:537389614
1138 1138 a, g dbSNP:770550698
1140 1140 a, g dbSNP:568267104
1144 1144 c, t dbSNP:777215195
1151 1151 a, g dbSNP:111247129
1157 1157 c, t dbSNP:752242946
1165 1165 c, t dbSNP:781100312
1166 1166 a, g dbSNP:367607708
1175 1175 c, g dbSNP:751306546
1176 1176 a, g dbSNP:766088248
1178 1178 c, t dbSNP:763190160
1181 1181 c, t dbSNP:374905687
1225 1225 c, g dbSNP:565640244
1230 1230 c, t dbSNP:552011940
1254 1254 a, g dbSNP:532070966
1260 1260 c, g dbSNP:759871319
1333 1333 c, t dbSNP:564388541
1366 1366 a, c dbSNP:528039915
1380 1380 a, g dbSNP:150353666
1383 1383 c, t dbSNP:550767682
1415 1415 a, g dbSNP:1050616
1431 1431 a, g dbSNP:562260102
1459 1459 c, g dbSNP:558556704
1477 1477 c, g dbSNP:542481995
1483 1483 c, t dbSNP:562092597
1504 1504 a, g dbSNP:749335137
1582 1582 a, g dbSNP:183081542
1596 1596 g, t dbSNP:773890769
1619 1619 a, g dbSNP:16916652
1634 1634 c, t dbSNP:112005671
1699 1699 g, t dbSNP:748647963
1703 1703 a, g dbSNP:141188432
1712 1712 c, t dbSNP:189913609
1713 1713 a, g dbSNP:17036
1723 1723 a, g dbSNP:17847131
1782 1782 g, t dbSNP:779516648
1824 1824 -, a dbSNP:554766514
1842 1842 a, t dbSNP:76872543
1854 1854 a, t dbSNP:554586328
1859 1859 c, g dbSNP:757909116
1868 1868 c, t dbSNP:575351637
1887 1887 a, g dbSNP:534895232
1912 1912 a, c, g dbSNP:565572968
1930 1930 c, t dbSNP:757234360
1939 1939 a, g dbSNP:185901996
1952 1952 c, t dbSNP:11985
1963 1963 c, t dbSNP:113737568
1968 1968 c, t dbSNP:17734604
1970 1970 a, g dbSNP:377650284
1975 1975 c, t dbSNP:1050627
1986 1986 g, t dbSNP:2623167
2001 2001 c, t dbSNP:768211381
2002 2002 g, t dbSNP:539745441
2034 2034 c, t dbSNP:746650472
2055 2055 c, t dbSNP:183026760
2060 2060 a, g dbSNP:145900354
2062 2062 g, t dbSNP:775136620
2101 2101 a, g dbSNP:528771219
2112 2112 a, g dbSNP:772351189
2134 2134 c, t dbSNP:559533613
2138 2138 a, c dbSNP:546222960
2151 2151 a, g dbSNP:769967456
2185 2185 a, g dbSNP:532507604

Target ORF information:

RefSeq Version NM_005261
Organism Homo sapiens (human)
Definition Homo sapiens GTP binding protein overexpressed in skeletal muscle (GEM), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_005261

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
ATGACTCTGA ATAATGTCAC CATGCGCCAG GGCACTGTGG GCATGCAGCC ACAGCAGCAG 
CGCTGGAGCA TCCCAGCTGA TGGCAGGCAT CTGATGGTCC AGAAAGAGCC CCACCAGTAC
AGCCACCGCA ACCGCCATTC TGCTACCCCT GAGGACCACT GCCGCCGAAG CTGGTCCTCT
GACTCCACAG ACTCAGTCAT CTCCTCTGAG TCAGGGAACA CCTACTACCG AGTGGTGCTC
ATAGGGGAGC AGGGGGTGGG CAAGTCCACT CTGGCCAACA TCTTTGCAGG TGTGCATGAC
AGCATGGACA GCGACTGCGA GGTGCTGGGA GAAGATACAT ATGAACGAAC CCTGATGGTT
GATGGGGAAA GTGCAACGAT TATACTCCTG GATATGTGGG AAAATAAGGG GGAAAATGAA
TGGCTCCATG ACCACTGCAT GCAGGTCGGG GACGCATACC TGATTGTCTA CTCAATCACA
GACCGAGCGA GCTTCGAGAA GGCATCTGAG CTGCGAATCC AGCTCCGCAG GGCCCGGCAG
ACAGAGGACA TTCCCATAAT TTTGGTTGGC AACAAAAGTG ACTTAGTGCG GTGCCGAGAA
GTGTCTGTAT CAGAAGGGAG AGCCTGTGCA GTGGTGTTTG ACTGCAAGTT CATCGAGACC
TCTGCAGCTG TCCAGCACAA CGTGAAGGAG CTGTTTGAGG GCATTGTGCG ACAGGTGCGC
CTTCGGCGGG ACAGCAAGGA GAAGAATGAA CGGCGGCTGG CCTACCAGAA AAGGAAGGAG
AGCATGCCCA GGAAAGCCAG GCGCTTCTGG GGCAAGATCG TGGCCAAAAA CAACAAGAAT
ATGGCCTTCA AGCTCAAGTC CAAATCCTGC CATGACCTCT CTGTACTCTA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu01836
Accession Version NM_181702.2
Sequence Information ORF Nucleotide Sequence (Length: 891bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product GTP-binding protein GEM
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC022010.2 and AP003478.1. On Oct 6, 2009 this sequence version replaced gi:32483370. Summary: The protein encoded by this gene belongs to the RAD/GEM family of GTP-binding proteins. It is associated with the inner face of the plasma membrane and could play a role as a regulatory protein in receptor-mediated signal transduction. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC022010.2, AK314017.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA962346 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
ATGACTCTGA ATAATGTCAC CATGCGCCAG GGCACTGTGG GCATGCAGCC ACAGCAGCAG 
CGCTGGAGCA TCCCAGCTGA TGGCAGGCAT CTGATGGTCC AGAAAGAGCC CCACCAGTAC
AGCCACCGCA ACCGCCATTC TGCTACCCCT GAGGACCACT GCCGCCGAAG CTGGTCCTCT
GACTCCACAG ACTCAGTCAT CTCCTCTGAG TCAGGGAACA CCTACTACCG AGTGGTGCTC
ATAGGGGAGC AGGGGGTGGG CAAGTCCACT CTGGCCAACA TCTTTGCAGG TGTGCATGAC
AGCATGGACA GCGACTGCGA GGTGCTGGGA GAAGATACAT ATGAACGAAC CCTGATGGTT
GATGGGGAAA GTGCAACGAT TATACTCCTG GATATGTGGG AAAATAAGGG GGAAAATGAA
TGGCTCCATG ACCACTGCAT GCAGGTCGGG GACGCATACC TGATTGTCTA CTCAATCACA
GACCGAGCGA GCTTCGAGAA GGCATCTGAG CTGCGAATCC AGCTCCGCAG GGCCCGGCAG
ACAGAGGACA TTCCCATAAT TTTGGTTGGC AACAAAAGTG ACTTAGTGCG GTGCCGAGAA
GTGTCTGTAT CAGAAGGGAG AGCCTGTGCA GTGGTGTTTG ACTGCAAGTT CATCGAGACC
TCTGCAGCTG TCCAGCACAA CGTGAAGGAG CTGTTTGAGG GCATTGTGCG ACAGGTGCGC
CTTCGGCGGG ACAGCAAGGA GAAGAATGAA CGGCGGCTGG CCTACCAGAA AAGGAAGGAG
AGCATGCCCA GGAAAGCCAG GCGCTTCTGG GGCAAGATCG TGGCCAAAAA CAACAAGAAT
ATGGCCTTCA AGCTCAAGTC CAAATCCTGC CATGACCTCT CTGTACTCTA G
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_859053.1
CDS125..1015
Misc Feature(1)350..1012(+)
Misc Feature(2)353..844(+)
Misc Feature(3)368..391(+)
Misc Feature(4)371..526(+)
Misc Feature(5)374..790(+)
Misc Feature(6)389..793(+)
Misc Feature(7)437..469(+)
Misc Feature(8)437..466(+)
Misc Feature(9)443..445(+)
Misc Feature(10)515..526(+)
Misc Feature(11)521..580(+)
Misc Feature(12)695..706(+)
Misc Feature(13)785..793(+)
Misc Feature(14)905..907(+)
Misc Feature(15)920..979(+)
Misc Feature(16)989..991(+)
Misc Feature(17)992..1003(+)
Exon (1)1..115
Gene:GEM
Gene Synonym:
Exon (2)116..455
Gene:GEM
Gene Synonym:
Exon (3)456..532
Gene:GEM
Gene Synonym:
Exon (4)533..737
Gene:GEM
Gene Synonym:
Exon (5)738..2072
Gene:GEM
Gene Synonym:
Translation
Position Chain Variation Link
15 15 a, g dbSNP:555106064
31 31 c, t dbSNP:535084384
42 42 c, g dbSNP:572301256
50 50 a, g dbSNP:781108102
65 65 c, g dbSNP:542397860
111 111 a, g dbSNP:755359530
122 122 a, g dbSNP:771858021
129 129 c, t dbSNP:746033873
131 131 -, ct dbSNP:755082119
140 140 a, g dbSNP:779094271
144 144 c, t dbSNP:771211990
147 147 c, t dbSNP:374909426
149 149 c, t dbSNP:777960854
150 150 a, g dbSNP:756531627
156 156 a, c, g dbSNP:556308745
164 164 a, g dbSNP:542542829
165 165 a, g dbSNP:370415265
168 168 c, t dbSNP:34218332
170 170 c, t dbSNP:764949315
174 174 c, t dbSNP:761603767
182 182 c, t dbSNP:753235715
185 185 c, t dbSNP:140549853
190 190 g, t dbSNP:760461262
192 192 a, g dbSNP:775511173
202 202 c, t dbSNP:151310883
211 211 a, g dbSNP:759323238
212 212 c, t dbSNP:774173558
225 225 a, g dbSNP:771122242
228 228 a, t dbSNP:11539260
229 229 a, g dbSNP:749549314
232 232 a, g, t dbSNP:769925332
236 236 c, t dbSNP:35262320
240 240 a, g dbSNP:781762421
242 242 g, t dbSNP:755579538
250 250 c, g, t dbSNP:35065846
251 251 c, g, t dbSNP:2170363
253 253 c, t dbSNP:756928867
255 255 a, c, g dbSNP:763453975
257 257 -, cc dbSNP:144891099
257 257 a, c, t dbSNP:201351710
258 258 a, g dbSNP:17847126
268 268 c, t dbSNP:759521195
269 269 a, g dbSNP:774085906
270 270 c, t dbSNP:766195976
271 271 c, t dbSNP:763022208
272 272 c, t dbSNP:147133582
274 274 c, t dbSNP:769973168
283 283 c, t dbSNP:748224959
286 286 c, t dbSNP:776897188
287 287 c, t dbSNP:769234376
289 289 c, t dbSNP:747548067
291 291 a, g dbSNP:780498125
298 298 -, g dbSNP:774839596
300 300 c, t dbSNP:758803093
306 306 a, c dbSNP:746276333
307 307 c, g dbSNP:145616833
309 309 c, t dbSNP:755764047
319 319 a, g dbSNP:145046153
321 321 a, t dbSNP:767038807
328 328 -, ctc dbSNP:764523532
328 328 c, t dbSNP:780164919
330 330 c, g dbSNP:754873278
339 339 a, g dbSNP:751506282
343 343 c, t dbSNP:766109484
345 345 a, c dbSNP:762800000
348 348 a, g dbSNP:772917669
350 350 c, t dbSNP:765472126
353 353 c, t dbSNP:550393204
354 354 a, g dbSNP:761960990
358 358 c, g dbSNP:776810929
359 359 a, g dbSNP:768860314
361 361 a, g dbSNP:747460145
369 369 a, g dbSNP:776127220
373 373 a, g dbSNP:772521690
375 375 a, g dbSNP:201303048
377 377 c, g dbSNP:139494082
378 378 a, g dbSNP:567967510
387 387 a, g dbSNP:567771198
392 392 a, g dbSNP:747832501
394 394 g, t dbSNP:780616166
420 420 a, g dbSNP:754500839
427 427 -, catgg dbSNP:763246450
429 429 g, t dbSNP:751132195
434 434 a, t dbSNP:780005500
436 436 c, t dbSNP:758312817
437 437 a, g dbSNP:548062745
440 440 c, t dbSNP:764970254
441 441 a, g dbSNP:762025958
442 442 c, t dbSNP:754124324
443 443 a, g dbSNP:527705763
445 445 a, g dbSNP:201792479
461 461 a, g dbSNP:201677240
462 462 c, t dbSNP:757104245
470 470 c, t dbSNP:762667312
481 481 c, g dbSNP:764380913
482 482 c, g dbSNP:761027449
483 483 c, t dbSNP:530616234
489 489 a, g, t dbSNP:767526831
490 490 a, g dbSNP:773047264
497 497 a, g dbSNP:774736541
501 501 c, t dbSNP:184919570
502 502 a, g dbSNP:763307759
515 515 a, g dbSNP:773612061
534 534 a, g dbSNP:200005791
537 537 a, t dbSNP:751732240
538 538 a, g dbSNP:144483271
539 539 a, g dbSNP:763469017
564 564 c, t dbSNP:557922897
566 566 c, g dbSNP:773522304
571 571 a, c, t dbSNP:760261186
572 572 a, g dbSNP:774991627
577 577 c, t dbSNP:374944377
578 578 a, g dbSNP:372249284
590 590 c, g dbSNP:773969361
594 594 a, g dbSNP:770754951
597 597 c, g dbSNP:770933590
601 601 a, c dbSNP:554056106
607 607 c, t dbSNP:777669807
609 609 a, g dbSNP:149283301
612 612 c, t dbSNP:748020922
613 613 a, g dbSNP:762856348
619 619 c, t dbSNP:571339649
620 620 a, g dbSNP:781236754
626 626 a, c, g dbSNP:751539968
629 629 c, t dbSNP:766455469
637 637 a, g dbSNP:758865296
639 639 a, g dbSNP:750953687
645 645 a, c dbSNP:201731029
647 647 c, t dbSNP:762054664
650 650 c, t dbSNP:777120814
651 651 a, g, t dbSNP:759240105
652 652 c, t dbSNP:773931272
657 657 c, t dbSNP:770594268
659 659 c, t dbSNP:577912523
666 666 a, c dbSNP:74360159
679 679 c, t dbSNP:368254970
691 691 c, t dbSNP:769889864
693 693 c, g dbSNP:375183063
706 706 c, t dbSNP:762942878
713 713 c, t dbSNP:187593880
716 716 c, t dbSNP:558611127
719 719 c, t dbSNP:138582164
720 720 a, g dbSNP:780063278
731 731 a, g dbSNP:758453208
746 746 g, t dbSNP:778977780
754 754 a, g dbSNP:199789983
758 758 a, g dbSNP:754399008
778 778 c, g, t dbSNP:138012458
779 779 a, g dbSNP:753149152
783 783 a, c dbSNP:766122201
804 804 a, g dbSNP:762747900
806 806 a, g dbSNP:370285889
807 807 g, t dbSNP:764837790
811 811 a, g dbSNP:764235966
823 823 a, g dbSNP:761609378
826 826 c, g dbSNP:776610861
827 827 a, g dbSNP:141761903
833 833 a, c, t dbSNP:138147292
834 834 a, g dbSNP:368821999
839 839 a, g dbSNP:746095122
842 842 c, t dbSNP:190907564
843 843 a, g dbSNP:771063860
848 848 c, t dbSNP:749374110
851 851 c, t dbSNP:778310132
852 852 a, g dbSNP:200768882
853 853 g, t dbSNP:748506771
856 856 c, t dbSNP:781697524
863 863 a, g dbSNP:141202489
871 871 c, t dbSNP:750125754
875 875 c, t dbSNP:200775391
878 878 c, t dbSNP:138265181
879 879 a, g dbSNP:375369112
882 882 c, t dbSNP:764080201
884 884 g, t dbSNP:760620813
886 886 c, g dbSNP:775199448
897 897 g, t dbSNP:148957520
902 902 c, g dbSNP:759705261
904 904 c, g dbSNP:774608878
905 905 a, g dbSNP:771095990
906 906 a, g dbSNP:749379436
908 908 -, atgc dbSNP:746154399
908 908 a, g dbSNP:773218409
910 910 a, g dbSNP:770363121
921 921 c, t dbSNP:748700800
922 922 c, g dbSNP:551066990
926 926 c, t dbSNP:755375862
927 927 a, g dbSNP:145789382
928 928 c, t dbSNP:778625070
937 937 c, t dbSNP:530942518
939 939 a, g dbSNP:753332084
943 943 c, t dbSNP:201686704
944 944 a, g dbSNP:149831559
957 957 a, g dbSNP:752653844
958 958 a, c dbSNP:767490302
961 961 c, g dbSNP:759294461
963 963 a, c dbSNP:557181794
969 969 a, c dbSNP:372371105
977 977 c, t dbSNP:766608259
979 979 c, g dbSNP:142606096
988 988 a, g dbSNP:773272814
989 989 c, t dbSNP:770019011
995 995 c, t dbSNP:762037099
996 996 a, t dbSNP:777248979
998 998 g, t dbSNP:769356943
1004 1004 g, t dbSNP:747387622
1010 1010 c, t dbSNP:537389614
1023 1023 a, g dbSNP:770550698
1025 1025 a, g dbSNP:568267104
1029 1029 c, t dbSNP:777215195
1036 1036 a, g dbSNP:111247129
1042 1042 c, t dbSNP:752242946
1050 1050 c, t dbSNP:781100312
1051 1051 a, g dbSNP:367607708
1060 1060 c, g dbSNP:751306546
1061 1061 a, g dbSNP:766088248
1063 1063 c, t dbSNP:763190160
1066 1066 c, t dbSNP:374905687
1110 1110 c, g dbSNP:565640244
1115 1115 c, t dbSNP:552011940
1139 1139 a, g dbSNP:532070966
1145 1145 c, g dbSNP:759871319
1218 1218 c, t dbSNP:564388541
1251 1251 a, c dbSNP:528039915
1265 1265 a, g dbSNP:150353666
1268 1268 c, t dbSNP:550767682
1300 1300 a, g dbSNP:1050616
1316 1316 a, g dbSNP:562260102
1344 1344 c, g dbSNP:558556704
1362 1362 c, g dbSNP:542481995
1368 1368 c, t dbSNP:562092597
1389 1389 a, g dbSNP:749335137
1467 1467 a, g dbSNP:183081542
1481 1481 g, t dbSNP:773890769
1504 1504 a, g dbSNP:16916652
1519 1519 c, t dbSNP:112005671
1584 1584 g, t dbSNP:748647963
1588 1588 a, g dbSNP:141188432
1597 1597 c, t dbSNP:189913609
1598 1598 a, g dbSNP:17036
1608 1608 a, g dbSNP:17847131
1667 1667 g, t dbSNP:779516648
1709 1709 -, a dbSNP:554766514
1727 1727 a, t dbSNP:76872543
1739 1739 a, t dbSNP:554586328
1744 1744 c, g dbSNP:757909116
1753 1753 c, t dbSNP:575351637
1772 1772 a, g dbSNP:534895232
1797 1797 a, c, g dbSNP:565572968
1815 1815 c, t dbSNP:757234360
1824 1824 a, g dbSNP:185901996
1837 1837 c, t dbSNP:11985
1848 1848 c, t dbSNP:113737568
1853 1853 c, t dbSNP:17734604
1855 1855 a, g dbSNP:377650284
1860 1860 c, t dbSNP:1050627
1871 1871 g, t dbSNP:2623167
1886 1886 c, t dbSNP:768211381
1887 1887 g, t dbSNP:539745441
1919 1919 c, t dbSNP:746650472
1940 1940 c, t dbSNP:183026760
1945 1945 a, g dbSNP:145900354
1947 1947 g, t dbSNP:775136620
1986 1986 a, g dbSNP:528771219
1997 1997 a, g dbSNP:772351189
2019 2019 c, t dbSNP:559533613
2023 2023 a, c dbSNP:546222960
2036 2036 a, g dbSNP:769967456
2070 2070 a, g dbSNP:532507604

Target ORF information:

RefSeq Version NM_181702
Organism Homo sapiens (human)
Definition Homo sapiens GTP binding protein overexpressed in skeletal muscle (GEM), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_181702

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
ATGACTCTGA ATAATGTCAC CATGCGCCAG GGCACTGTGG GCATGCAGCC ACAGCAGCAG 
CGCTGGAGCA TCCCAGCTGA TGGCAGGCAT CTGATGGTCC AGAAAGAGCC CCACCAGTAC
AGCCACCGCA ACCGCCATTC TGCTACCCCT GAGGACCACT GCCGCCGAAG CTGGTCCTCT
GACTCCACAG ACTCAGTCAT CTCCTCTGAG TCAGGGAACA CCTACTACCG AGTGGTGCTC
ATAGGGGAGC AGGGGGTGGG CAAGTCCACT CTGGCCAACA TCTTTGCAGG TGTGCATGAC
AGCATGGACA GCGACTGCGA GGTGCTGGGA GAAGATACAT ATGAACGAAC CCTGATGGTT
GATGGGGAAA GTGCAACGAT TATACTCCTG GATATGTGGG AAAATAAGGG GGAAAATGAA
TGGCTCCATG ACCACTGCAT GCAGGTCGGG GACGCATACC TGATTGTCTA CTCAATCACA
GACCGAGCGA GCTTCGAGAA GGCATCTGAG CTGCGAATCC AGCTCCGCAG GGCCCGGCAG
ACAGAGGACA TTCCCATAAT TTTGGTTGGC AACAAAAGTG ACTTAGTGCG GTGCCGAGAA
GTGTCTGTAT CAGAAGGGAG AGCCTGTGCA GTGGTGTTTG ACTGCAAGTT CATCGAGACC
TCTGCAGCTG TCCAGCACAA CGTGAAGGAG CTGTTTGAGG GCATTGTGCG ACAGGTGCGC
CTTCGGCGGG ACAGCAAGGA GAAGAATGAA CGGCGGCTGG CCTACCAGAA AAGGAAGGAG
AGCATGCCCA GGAAAGCCAG GCGCTTCTGG GGCAAGATCG TGGCCAAAAA CAACAAGAAT
ATGGCCTTCA AGCTCAAGTC CAAATCCTGC CATGACCTCT CTGTACTCTA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.