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GHRHR growth hormone releasing hormone receptor [Homo sapiens (human)]

Gene Symbol GHRHR
Entrez Gene ID 2692
Full Name growth hormone releasing hormone receptor
Synonyms GHRFR, GRFR, IGHD1B
General protein information
Preferred Names
growth hormone-releasing hormone receptor
Names
growth hormone-releasing hormone receptor
GRF receptor
GHRH receptor
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

7

7p14

Summary This gene encodes a receptor for growth hormone-releasing hormone. Binding of this hormone to the receptor leads to synthesis and release of growth hormone. Mutations in this gene have been associated with isolated growth hormone deficiency (IGHD), also known as Dwarfism of Sindh, a disorder characterized by short stature. [provided by RefSeq, Jun 2010]. lac of sum
Disorder MIM:

139191

Disorder Html: Growth hormone deficiency, isolated, type IB, 612781 (3)





The following GHRHR gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GHRHR gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu18044 NM_000823 Homo sapiens growth hormone releasing hormone receptor (GHRHR), mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $319
OHu57966 XM_011515263 PREDICTED: Homo sapiens growth hormone releasing hormone receptor (GHRHR), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $319

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu18044
Accession Version NM_000823.3
Sequence Information ORF Nucleotide Sequence (Length: 1272bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 03-MAY-2014
Organism Homo sapiens (human)
Product growth hormone-releasing hormone receptor precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from L09237.1 and DB348314.1. This sequence is a reference standard in the RefSeqGene project. On Jun 2, 2010 this sequence version replaced gi:58530850. Summary: This gene encodes a receptor for growth hormone-releasing hormone. Binding of this hormone to the receptor leads to synthesis and release of growth hormone. Mutations in this gene have been associated with isolated growth hormone deficiency (IGHD), also known as Dwarfism of Sindh, a disorder characterized by short stature. [provided by RefSeq, Jun 2010]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: L01406.1, AY557192.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGGACCGCC GGATGTGGGG GGCCCACGTC TTCTGCGTGT TGAGCCCGTT ACCGACCGTA 
TTGGGCCACA TGCACCCAGA ATGTGACTTC ATCACCCAGC TGAGAGAGGA TGAGAGTGCC
TGTCTACAAG CAGCAGAGGA GATGCCCAAC ACCACCCTGG GCTGCCCTGC GACCTGGGAT
GGGCTGCTGT GCTGGCCAAC GGCAGGCTCT GGCGAGTGGG TCACCCTCCC CTGCCCGGAT
TTCTTCTCTC ACTTCAGCTC AGAGTCAGGG GCTGTGAAAC GGGATTGTAC TATCACTGGC
TGGTCTGAGC CCTTTCCACC TTACCCTGTG GCCTGCCCTG TGCCTCTGGA GCTGCTGGCT
GAGGAGGAAT CTTACTTCTC CACAGTGAAG ATTATCTACA CCGTGGGCCA TAGCATCTCT
ATTGTAGCCC TCTTCGTGGC CATCACCATC CTGGTTGCTC TCAGGAGGCT CCACTGCCCC
CGGAACTACG TCCACACCCA GCTGTTCACC ACTTTTATCC TCAAGGCGGG AGCTGTGTTC
CTGAAGGATG CTGCCCTTTT CCACAGCGAC GACACTGACC ACTGCAGCTT CTCCACTGTT
CTATGCAAGG TCTCTGTGGC CGCCTCCCAT TTCGCCACCA TGACCAACTT CAGCTGGCTG
TTGGCAGAAG CCGTCTACCT GAACTGCCTC CTGGCCTCCA CCTCCCCCAG CTCAAGGAGA
GCCTTCTGGT GGCTGGTTCT CGCTGGCTGG GGGCTGCCCG TGCTCTTCAC TGGCACGTGG
GTGAGCTGCA AACTGGCCTT CGAGGACATC GCGTGCTGGG ACCTGGACGA CACCTCCCCC
TACTGGTGGA TCATCAAAGG GCCCATTGTC CTCTCGGTCG GGGTGAACTT TGGGCTTTTT
CTCAATATTA TCCGCATCCT GGTGAGGAAA CTGGAGCCAG CTCAGGGCAG CCTCCATACC
CAGTCTCAGT ATTGGCGTCT CTCCAAGTCG ACACTTTTCC TGATCCCACT CTTTGGAATT
CACTACATCA TCTTCAACTT CCTGCCAGAC AATGCTGGCC TGGGCATCCG CCTCCCCCTG
GAGCTGGGAC TGGGTTCCTT CCAGGGCTTC ATTGTTGCCA TCCTCTACTG CTTCCTCAAC
CAAGAGGTGA GGACTGAGAT CTCACGGAAG TGGCATGGCC ATGACCCTGA GCTTCTGCCA
GCCTGGAGGA CCCGTGCTAA GTGGACCACG CCTTCCCGCT CGGCGGCAAA GGTGCTGACA
TCTATGTGCT AG
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_000814.2
CDS49..1320
Misc Feature(1)202..384(+)
Misc Feature(2)424..1164(+)
Misc Feature(3)445..504(+)
Misc Feature(4)535..591(+)
Misc Feature(5)661..729(+)
Misc Feature(6)769..834(+)
Misc Feature(7)889..960(+)
Misc Feature(8)1036..1092(+)
Misc Feature(9)1132..1191(+)
Exon (1)1..105
Gene:GHRHR
Gene Synonym:
Exon (2)106..208
Gene:GHRHR
Gene Synonym:
Exon (3)209..316
Gene:GHRHR
Gene Synonym:
Exon (4)317..414
Gene:GHRHR
Gene Synonym:
Exon (5)415..512
Gene:GHRHR
Gene Synonym:
Exon (6)513..645
Gene:GHRHR
Gene Synonym:
Exon (7)646..799
Gene:GHRHR
Gene Synonym:
Exon (8)800..860
Gene:GHRHR
Gene Synonym:
Exon (9)861..930
Gene:GHRHR
Gene Synonym:
Exon (10)931..1022
Gene:GHRHR
Gene Synonym:
Exon (11)1023..1152
Gene:GHRHR
Gene Synonym:
Exon (12)1153..1194
Gene:GHRHR
Gene Synonym:
Exon (13)1195..1607
Gene:GHRHR
Gene Synonym:
Translation
Position Chain Variation Link
4 4 c, t dbSNP:2302021
23 23 g, t dbSNP:781685119
26 26 a, g dbSNP:746306161
28 28 a, g dbSNP:199748692
35 35 c, t dbSNP:372803803
54 54 c, t dbSNP:148704543
55 55 c, t dbSNP:374847216
56 56 a, g dbSNP:768888026
58 58 c, t dbSNP:142361839
59 59 a, g dbSNP:573168850
70 70 a, g dbSNP:151265232
75 75 c, t dbSNP:534220273
77 77 g, t dbSNP:139599160
84 84 c, g, t dbSNP:559089371
90 90 c, g dbSNP:577365315
93 93 a, c dbSNP:760636304
95 95 c, t dbSNP:142833343
101 101 c, t dbSNP:202243828
102 102 a, g dbSNP:759152551
105 105 c, t dbSNP:780668137
111 111 a, g dbSNP:768567586
115 115 c, t dbSNP:372707560
118 118 a, t dbSNP:779229085
119 119 g, t dbSNP:748254784
121 121 c, g dbSNP:772010422
123 123 c, t dbSNP:773131832
129 129 a, g dbSNP:760761162
135 135 c, t dbSNP:770962010
141 141 c, t dbSNP:143429066
144 144 c, t dbSNP:759110872
168 168 c, g dbSNP:764582464
174 174 a, c dbSNP:146723194
181 181 g, t dbSNP:762580559
183 183 a, t dbSNP:201978703
184 184 -, gag dbSNP:773323831
186 186 a, g dbSNP:375206873
189 189 c, g dbSNP:140417128
192 192 a, g dbSNP:756658887
199 199 a, g dbSNP:141571344
207 207 g, t dbSNP:754256570
209 209 g, t dbSNP:766587678
212 212 g, t dbSNP:754386566
213 213 c, t dbSNP:755430803
217 217 a, g dbSNP:4988496
218 218 c, t dbSNP:752793580
219 219 a, g dbSNP:369751652
222 222 a, c, g dbSNP:540740642
237 237 c, g dbSNP:565445448
245 245 a, c dbSNP:577536745
248 248 c, t dbSNP:201893637
249 249 a, g dbSNP:563078420
255 255 c, t dbSNP:769587851
256 256 a, g, t dbSNP:775025721
261 261 c, t dbSNP:768112214
262 262 g, t dbSNP:121918117
267 267 a, g dbSNP:761399375
274 274 a, c dbSNP:547825255
278 278 c, t dbSNP:776859854
281 281 g, t dbSNP:760129030
284 284 c, t dbSNP:765640577
285 285 a, g dbSNP:28371558
296 296 c, t dbSNP:758585465
301 301 c, t dbSNP:764209354
312 312 a, g dbSNP:751885823
320 320 c, t dbSNP:144372265
322 322 a, g dbSNP:767565179
328 328 c, t dbSNP:376258046
329 329 a, g, t dbSNP:200848306
334 334 c, t dbSNP:753601167
337 337 -, actatc dbSNP:751286749
340 340 a, g dbSNP:368351143
348 348 c, t dbSNP:549665869
350 350 a, c, g dbSNP:752643497
352 352 g, t dbSNP:777282249
357 357 c, g dbSNP:746703614
358 358 c, g dbSNP:756936955
365 365 c, t dbSNP:780610524
375 375 c, t dbSNP:749688300
376 376 a, g dbSNP:149024880
379 379 g, t dbSNP:774724170
384 384 c, t dbSNP:143017246
388 388 c, g dbSNP:200504469
400 400 a, c dbSNP:773339685
401 401 g, t dbSNP:760929445
402 402 a, g dbSNP:766566547
407 407 c, t dbSNP:138751215
411 411 g, t dbSNP:4988498
419 419 a, c dbSNP:747115030
420 420 g, t dbSNP:112879406
421 421 c, t dbSNP:770962593
433 433 a, g dbSNP:568588560
436 436 a, g dbSNP:544695401
443 443 g, t dbSNP:759699366
447 447 c, t dbSNP:765003087
451 451 a, g dbSNP:201267804
455 455 a, g dbSNP:762844006
463 463 a, g dbSNP:764111938
466 466 c, t dbSNP:606231412
469 469 a, g dbSNP:535557319
479 479 a, t dbSNP:121918118
483 483 c, t dbSNP:368335119
495 495 c, t dbSNP:753197652
496 496 a, g dbSNP:750156453
499 499 c, t dbSNP:755821865
506 506 c, t dbSNP:779187338
513 513 a, g dbSNP:753393038
529 529 -, c dbSNP:35515360
529 529 c, t dbSNP:758798716
533 533 a, t dbSNP:746565662
537 537 c, t dbSNP:147098353
538 538 a, g dbSNP:138615339
543 543 a, c dbSNP:606231413
546 546 a, c dbSNP:199684610
555 555 c, g, t dbSNP:570281194
560 560 c, g dbSNP:10227922
564 564 a, t dbSNP:150685406
569 569 a, t dbSNP:749412526
574 574 a, g dbSNP:768552934
575 575 c, t dbSNP:774281185
576 576 a, g, t dbSNP:139700235
585 585 c, g dbSNP:773236300
586 586 c, t dbSNP:146301048
598 598 c, g dbSNP:765740795
599 599 c, t dbSNP:372859999
609 609 c, t dbSNP:200623488
612 612 c, t dbSNP:740336
615 615 -, cga dbSNP:528011334
615 615 c, t dbSNP:764513071
618 618 c, t dbSNP:751896982
619 619 a, g dbSNP:757565895
623 623 c, t dbSNP:567290022
628 628 c, t dbSNP:377182945
629 629 a, g dbSNP:773735226
631 631 c, t dbSNP:750825992
646 646 a, g dbSNP:144251858
656 656 a, t dbSNP:755061353
664 664 a, g dbSNP:568908542
668 668 c, t dbSNP:779310511
669 669 c, t dbSNP:748314569
670 670 a, g dbSNP:758281879
672 672 c, t dbSNP:777420716
681 681 a, c, t dbSNP:747039896
682 682 a, g dbSNP:371191800
688 688 a, g dbSNP:535947130
706 706 c, t dbSNP:146727093
708 708 a, g dbSNP:145466944
713 713 a, c dbSNP:121918120
720 720 c, t dbSNP:376278130
721 721 a, g dbSNP:28371560
725 725 a, g dbSNP:773416694
729 729 c, g dbSNP:761291980
735 735 c, t dbSNP:766819346
748 748 a, c dbSNP:754331838
751 751 a, t dbSNP:759693561
754 754 c, t dbSNP:765351703
755 755 c, t dbSNP:142710091
769 769 a, g dbSNP:753030388
773 773 g, t dbSNP:121918119
777 777 a, g dbSNP:758693864
789 789 c, t dbSNP:151019928
790 790 a, g dbSNP:751292754
795 795 c, t dbSNP:757034595
807 807 c, t dbSNP:372209255
808 808 a, g dbSNP:375562610
811 811 a, c dbSNP:764172835
824 824 c, t dbSNP:774492929
825 825 a, g dbSNP:368859494
834 834 c, g dbSNP:762086691
836 836 g, t dbSNP:767254698
839 839 a, g dbSNP:750194553
844 844 a, g dbSNP:140869993
849 849 c, t dbSNP:562517014
850 850 a, g dbSNP:753708857
853 853 c, g dbSNP:529712059
855 855 c, t dbSNP:778474030
858 858 c, t dbSNP:747823161
859 859 a, c, g dbSNP:149678088
860 860 c, t dbSNP:547906129
874 874 a, g dbSNP:201748357
876 876 c, t dbSNP:147768462
877 877 a, g dbSNP:774670785
882 882 c, t dbSNP:773069868
885 885 c, g, t dbSNP:748290640
886 886 c, g dbSNP:773436596
887 887 c, t dbSNP:141237359
890 890 a, g dbSNP:770780823
902 902 a, t dbSNP:776458189
909 909 c, g dbSNP:759443322
912 912 c, t dbSNP:559861727
918 918 c, t dbSNP:369716383
921 921 c, t dbSNP:374443097
923 923 a, c, g, t dbSNP:527387367
924 924 a, c, g, t dbSNP:370074960
927 927 a, c, t dbSNP:375674796
928 928 c, g dbSNP:748546851
933 933 a, g, t dbSNP:146944568
937 937 c, t dbSNP:757289905
940 940 a, g dbSNP:781485380
943 943 c, t dbSNP:267601482
944 944 a, t dbSNP:748809967
945 945 c, t dbSNP:746022932
955 955 a, g dbSNP:769693204
962 962 a, g dbSNP:200472991
965 965 c, t dbSNP:749285757
973 973 a, g dbSNP:768735519
988 988 g, t dbSNP:138492645
989 989 c, g dbSNP:761412028
995 995 g, t dbSNP:747239719
1008 1008 c, t dbSNP:376273824
1009 1009 a, c dbSNP:772975589
1011 1011 c, g dbSNP:760242094
1013 1013 c, g dbSNP:768685160
1024 1024 c, t dbSNP:763314210
1025 1025 a, g dbSNP:535727568
1033 1033 a, g dbSNP:121918121
1037 1037 c, t dbSNP:752122561
1038 1038 a, g dbSNP:369089111
1055 1055 c, t dbSNP:149182247
1057 1057 c, t dbSNP:202089170
1062 1062 c, t dbSNP:750488020
1065 1065 a, g dbSNP:756177266
1074 1074 c, t dbSNP:780426452
1075 1075 a, g dbSNP:372024874
1078 1078 a, t dbSNP:754054724
1084 1084 a, g dbSNP:565529920
1090 1090 c, t dbSNP:778848120
1092 1092 g, t dbSNP:748136929
1098 1098 c, t dbSNP:771883010
1101 1101 c, t dbSNP:777718663
1105 1105 g, t dbSNP:746533943
1106 1106 a, g dbSNP:770409961
1108 1108 c, t dbSNP:776282236
1110 1110 c, g dbSNP:143333500
1117 1117 c, t dbSNP:376948691
1118 1118 a, g, t dbSNP:201403615
1119 1119 a, c dbSNP:557474309
1122 1122 c, t dbSNP:576049917
1124 1124 c, t dbSNP:200417925
1135 1135 -, ggact dbSNP:748432685
1139 1139 c, t dbSNP:766553585
1156 1156 c, t dbSNP:373883983
1161 1161 g, t dbSNP:751521824
1165 1165 a, g dbSNP:199990600
1166 1166 -, ccat dbSNP:772601101
1178 1178 a, g dbSNP:757160765
1188 1188 c, t dbSNP:375995048
1193 1193 a, t dbSNP:781055325
1194 1194 a, g dbSNP:200743419
1195 1195 g, t dbSNP:747380710
1209 1209 c, g, t dbSNP:771381012
1213 1213 c, t dbSNP:200508601
1214 1214 a, g dbSNP:769801107
1220 1220 g, t dbSNP:748027900
1235 1235 c, g dbSNP:775631493
1238 1238 -, agcttctgcc dbSNP:778207215
1238 1238 a, c dbSNP:550469546
1241 1241 g, t dbSNP:764385532
1247 1247 c, g dbSNP:774400027
1252 1252 g, t dbSNP:761620728
1256 1256 c, g, t dbSNP:767279880
1261 1261 c, t dbSNP:28371561
1262 1262 a, g dbSNP:189950019
1264 1264 a, g dbSNP:141571507
1274 1274 a, c dbSNP:754378932
1277 1277 c, t dbSNP:778657652
1278 1278 a, g dbSNP:752346076
1285 1285 c, t dbSNP:757742182
1286 1286 a, g dbSNP:781659959
1289 1289 -, ggcg dbSNP:747109235
1289 1289 c, t dbSNP:146305421
1290 1290 a, c, g dbSNP:28371562
1291 1291 a, g dbSNP:142878597
1293 1293 a, g dbSNP:181168274
1294 1294 a, g dbSNP:774608366
1296 1296 -, a dbSNP:771060895
1313 1313 c, t dbSNP:2228078
1316 1316 a, g dbSNP:139763309
1317 1317 c, g dbSNP:575480873
1326 1326 c, t dbSNP:369741931
1333 1333 c, t dbSNP:142228002
1334 1334 a, g dbSNP:766344455
1345 1345 a, c dbSNP:776509945
1349 1349 a, g dbSNP:759106817
1361 1361 a, g dbSNP:764629030
1368 1368 c, t dbSNP:374294592
1370 1370 a, t dbSNP:200055651
1371 1371 c, t dbSNP:185262577
1372 1372 a, g dbSNP:781726148
1406 1406 c, t dbSNP:35624572
1408 1408 a, t dbSNP:578006876
1433 1433 c, t dbSNP:190966223
1457 1457 c, t dbSNP:557566669
1467 1467 a, c dbSNP:2586
1541 1541 c, t dbSNP:28371563
1545 1545 c, t dbSNP:561615897
1556 1556 a, c dbSNP:28371564
1578 1578 a, g dbSNP:539807888

Target ORF information:

RefSeq Version NM_000823
Organism Homo sapiens (human)
Definition Homo sapiens growth hormone releasing hormone receptor (GHRHR), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_000823

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGGACCGCC GGATGTGGGG GGCCCACGTC TTCTGCGTGT TGAGCCCGTT ACCGACCGTA 
TTGGGCCACA TGCACCCAGA ATGTGACTTC ATCACCCAGC TGAGAGAGGA TGAGAGTGCC
TGTCTACAAG CAGCAGAGGA GATGCCCAAC ACCACCCTGG GCTGCCCTGC GACCTGGGAT
GGGCTGCTGT GCTGGCCAAC GGCAGGCTCT GGCGAGTGGG TCACCCTCCC CTGCCCGGAT
TTCTTCTCTC ACTTCAGCTC AGAGTCAGGG GCTGTGAAAC GGGATTGTAC TATCACTGGC
TGGTCTGAGC CCTTTCCACC TTACCCTGTG GCCTGCCCTG TGCCTCTGGA GCTGCTGGCT
GAGGAGGAAT CTTACTTCTC CACAGTGAAG ATTATCTACA CCGTGGGCCA TAGCATCTCT
ATTGTAGCCC TCTTCGTGGC CATCACCATC CTGGTTGCTC TCAGGAGGCT CCACTGCCCC
CGGAACTACG TCCACACCCA GCTGTTCACC ACTTTTATCC TCAAGGCGGG AGCTGTGTTC
CTGAAGGATG CTGCCCTTTT CCACAGCGAC GACACTGACC ACTGCAGCTT CTCCACTGTT
CTATGCAAGG TCTCTGTGGC CGCCTCCCAT TTCGCCACCA TGACCAACTT CAGCTGGCTG
TTGGCAGAAG CCGTCTACCT GAACTGCCTC CTGGCCTCCA CCTCCCCCAG CTCAAGGAGA
GCCTTCTGGT GGCTGGTTCT CGCTGGCTGG GGGCTGCCCG TGCTCTTCAC TGGCACGTGG
GTGAGCTGCA AACTGGCCTT CGAGGACATC GCGTGCTGGG ACCTGGACGA CACCTCCCCC
TACTGGTGGA TCATCAAAGG GCCCATTGTC CTCTCGGTCG GGGTGAACTT TGGGCTTTTT
CTCAATATTA TCCGCATCCT GGTGAGGAAA CTGGAGCCAG CTCAGGGCAG CCTCCATACC
CAGTCTCAGT ATTGGCGTCT CTCCAAGTCG ACACTTTTCC TGATCCCACT CTTTGGAATT
CACTACATCA TCTTCAACTT CCTGCCAGAC AATGCTGGCC TGGGCATCCG CCTCCCCCTG
GAGCTGGGAC TGGGTTCCTT CCAGGGCTTC ATTGTTGCCA TCCTCTACTG CTTCCTCAAC
CAAGAGGTGA GGACTGAGAT CTCACGGAAG TGGCATGGCC ATGACCCTGA GCTTCTGCCA
GCCTGGAGGA CCCGTGCTAA GTGGACCACG CCTTCCCGCT CGGCGGCAAA GGTGCTGACA
TCTATGTGCT AG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu57966
Accession Version XM_011515263.1
Sequence Information ORF Nucleotide Sequence (Length: 1080bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product growth hormone-releasing hormone receptor isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_007819.18) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGGTCCCTG GCACCCCCAG CCCCCTCCTG GGGAGAGGGA AGGAGTTGTG GCTAGAGAGT 
CTTGCTTGCC TCCCAGGGGC TGTGAAACGG GATTGTACTA TCACTGGCTG GTCTGAGCCC
TTTCCACCTT ACCCTGTGGC CTGCCCTGTG CCTCTGGAGC TGCTGGCTGA GGAGGAATCT
TACTTCTCCA CAGTGAAGAT TATCTACACC GTGGGCCATA GCATCTCTAT TGTAGCCCTC
TTCGTGGCCA TCACCATCCT GGTTGCTCTC AGGAGGCTCC ACTGCCCCCG GAACTACGTC
CACACCCAGC TGTTCACCAC TTTTATCCTC AAGGCGGGAG CTGTGTTCCT GAAGGATGCT
GCCCTTTTCC ACAGCGACGA CACTGACCAC TGCAGCTTCT CCACTGTTCT ATGCAAGGTC
TCTGTGGCCG CCTCCCATTT CGCCACCATG ACCAACTTCA GCTGGCTGTT GGCAGAAGCC
GTCTACCTGA ACTGCCTCCT GGCCTCCACC TCCCCCAGCT CAAGGAGAGC CTTCTGGTGG
CTGGTTCTCG CTGGCTGGGG GCTGCCCGTG CTCTTCACTG GCACGTGGGT GAGCTGCAAA
CTGGCCTTCG AGGACATCGC GTGCTGGGAC CTGGACGACA CCTCCCCCTA CTGGTGGATC
ATCAAAGGGC CCATTGTCCT CTCGGTCGGG GTGAACTTTG GGCTTTTTCT CAATATTATC
CGCATCCTGG TGAGGAAACT GGAGCCAGCT CAGGGCAGCC TCCATACCCA GTCTCAGTAT
TGGCGTCTCT CCAAGTCGAC ACTTTTCCTG ATCCCACTCT TTGGAATTCA CTACATCATC
TTCAACTTCC TGCCAGACAA TGCTGGCCTG GGCATCCGCC TCCCCCTGGA GCTGGGACTG
GGTTCCTTCC AGGGCTTCAT TGTTGCCATC CTCTACTGCT TCCTCAACCA AGAGGTGAGG
ACTGAGATCT CACGGAAGTG GCATGGCCAT GACCCTGAGC TTCTGCCAGC CTGGAGGACC
CGTGCTAAGT GGACCACGCC TTCCCGCTCG GCGGCAAAGG TGCTGACATC TATGTGCTAG
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqXP_011513565.1
CDS259..1338
Misc Feature(1)442..1182(+)
Translation
Position Chain Variation Link
36 36 c, t dbSNP:146177569
48 48 c, t dbSNP:71530540
52 52 c, t dbSNP:139773978
176 176 c, t dbSNP:144530630
206 206 c, t dbSNP:757505591
207 207 c, g dbSNP:574990233
215 215 c, t dbSNP:749154800
229 229 c, t dbSNP:768169711
233 233 c, t dbSNP:778382856
234 234 a, g dbSNP:542522971
240 240 a, t dbSNP:771592803
241 241 a, c dbSNP:777106467
242 242 c, t dbSNP:759843886
245 245 c, g dbSNP:192758467
250 250 a, g dbSNP:770158333
255 255 c, t dbSNP:776147793
261 261 a, g dbSNP:763538679
263 263 c, t dbSNP:764333738
263 263 -, t dbSNP:760708992
264 264 c, t dbSNP:751655333
272 272 -, c dbSNP:535628001
275 275 c, g dbSNP:527316151
276 276 c, t dbSNP:767655340
281 281 c, t dbSNP:750617700
284 284 c, t dbSNP:755864216
285 285 c, t dbSNP:781093112
290 290 c, g dbSNP:374386802
297 297 g, t dbSNP:779764987
299 299 -, agg dbSNP:776842530
299 299 a, g dbSNP:372175858
300 300 a, g dbSNP:754906142
304 304 c, t dbSNP:778435801
305 305 c, t dbSNP:747592779
309 309 g, t dbSNP:4988497
312 312 -, ag dbSNP:759669888
313 313 a, g dbSNP:777324294
315 315 a, g dbSNP:746608316
322 322 a, g, t dbSNP:770338509
327 327 c, t dbSNP:763591390
330 330 -, c dbSNP:764004356
330 330 c, t dbSNP:769260744
331 331 c, t dbSNP:774872773
338 338 c, t dbSNP:144372265
340 340 a, g dbSNP:767565179
346 346 c, t dbSNP:376258046
347 347 a, g, t dbSNP:200848306
352 352 c, t dbSNP:753601167
355 355 -, actatc dbSNP:751286749
358 358 a, g dbSNP:368351143
366 366 c, t dbSNP:549665869
368 368 a, c, g dbSNP:752643497
370 370 g, t dbSNP:777282249
375 375 c, g dbSNP:746703614
376 376 c, g dbSNP:756936955
383 383 c, t dbSNP:780610524
393 393 c, t dbSNP:749688300
394 394 a, g dbSNP:149024880
397 397 g, t dbSNP:774724170
402 402 c, t dbSNP:143017246
406 406 c, g dbSNP:200504469
418 418 a, c dbSNP:773339685
419 419 g, t dbSNP:760929445
420 420 a, g dbSNP:766566547
425 425 c, t dbSNP:138751215
429 429 g, t dbSNP:4988498
437 437 a, c dbSNP:747115030
438 438 g, t dbSNP:112879406
439 439 c, t dbSNP:770962593
451 451 a, g dbSNP:568588560
454 454 a, g dbSNP:544695401
461 461 g, t dbSNP:759699366
465 465 c, t dbSNP:765003087
469 469 a, g dbSNP:201267804
473 473 a, g dbSNP:762844006
481 481 a, g dbSNP:764111938
484 484 c, t dbSNP:606231412
487 487 a, g dbSNP:535557319
497 497 a, t dbSNP:121918118
501 501 c, t dbSNP:368335119
513 513 c, t dbSNP:753197652
514 514 a, g dbSNP:750156453
517 517 c, t dbSNP:755821865
524 524 c, t dbSNP:779187338
531 531 a, g dbSNP:753393038
547 547 -, c dbSNP:35515360
547 547 c, t dbSNP:758798716
551 551 a, t dbSNP:746565662
555 555 c, t dbSNP:147098353
556 556 a, g dbSNP:138615339
561 561 a, c dbSNP:606231413
564 564 a, c dbSNP:199684610
573 573 c, g, t dbSNP:570281194
578 578 c, g dbSNP:10227922
582 582 a, t dbSNP:150685406
587 587 a, t dbSNP:749412526
592 592 a, g dbSNP:768552934
593 593 c, t dbSNP:774281185
594 594 a, g, t dbSNP:139700235
603 603 c, g dbSNP:773236300
604 604 c, t dbSNP:146301048
616 616 c, g dbSNP:765740795
617 617 c, t dbSNP:372859999
627 627 c, t dbSNP:200623488
630 630 c, t dbSNP:740336
633 633 -, cga dbSNP:528011334
633 633 c, t dbSNP:764513071
636 636 c, t dbSNP:751896982
637 637 a, g dbSNP:757565895
641 641 c, t dbSNP:567290022
646 646 c, t dbSNP:377182945
647 647 a, g dbSNP:773735226
649 649 c, t dbSNP:750825992
664 664 a, g dbSNP:144251858
674 674 a, t dbSNP:755061353
682 682 a, g dbSNP:568908542
686 686 c, t dbSNP:779310511
687 687 c, t dbSNP:748314569
688 688 a, g dbSNP:758281879
690 690 c, t dbSNP:777420716
699 699 a, c, t dbSNP:747039896
700 700 a, g dbSNP:371191800
706 706 a, g dbSNP:535947130
724 724 c, t dbSNP:146727093
726 726 a, g dbSNP:145466944
731 731 a, c dbSNP:121918120
738 738 c, t dbSNP:376278130
739 739 a, g dbSNP:28371560
743 743 a, g dbSNP:773416694
747 747 c, g dbSNP:761291980
753 753 c, t dbSNP:766819346
766 766 a, c dbSNP:754331838
769 769 a, t dbSNP:759693561
772 772 c, t dbSNP:765351703
773 773 c, t dbSNP:142710091
787 787 a, g dbSNP:753030388
791 791 g, t dbSNP:121918119
795 795 a, g dbSNP:758693864
807 807 c, t dbSNP:151019928
808 808 a, g dbSNP:751292754
813 813 c, t dbSNP:757034595
825 825 c, t dbSNP:372209255
826 826 a, g dbSNP:375562610
829 829 a, c dbSNP:764172835
842 842 c, t dbSNP:774492929
843 843 a, g dbSNP:368859494
852 852 c, g dbSNP:762086691
854 854 g, t dbSNP:767254698
857 857 a, g dbSNP:750194553
862 862 a, g dbSNP:140869993
867 867 c, t dbSNP:562517014
868 868 a, g dbSNP:753708857
871 871 c, g dbSNP:529712059
873 873 c, t dbSNP:778474030
876 876 c, t dbSNP:747823161
877 877 a, c, g dbSNP:149678088
878 878 c, t dbSNP:547906129
892 892 a, g dbSNP:201748357
894 894 c, t dbSNP:147768462
895 895 a, g dbSNP:774670785
900 900 c, t dbSNP:773069868
903 903 c, g, t dbSNP:748290640
904 904 c, g dbSNP:773436596
905 905 c, t dbSNP:141237359
908 908 a, g dbSNP:770780823
920 920 a, t dbSNP:776458189
927 927 c, g dbSNP:759443322
930 930 c, t dbSNP:559861727
936 936 c, t dbSNP:369716383
939 939 c, t dbSNP:374443097
941 941 a, c, g, t dbSNP:527387367
942 942 a, c, g, t dbSNP:370074960
945 945 a, c, t dbSNP:375674796
946 946 c, g dbSNP:748546851
951 951 a, g, t dbSNP:146944568
955 955 c, t dbSNP:757289905
958 958 a, g dbSNP:781485380
961 961 c, t dbSNP:267601482
962 962 a, t dbSNP:748809967
963 963 c, t dbSNP:746022932
973 973 a, g dbSNP:769693204
980 980 a, g dbSNP:200472991
983 983 c, t dbSNP:749285757
991 991 a, g dbSNP:768735519
1006 1006 g, t dbSNP:138492645
1007 1007 c, g dbSNP:761412028
1013 1013 g, t dbSNP:747239719
1026 1026 c, t dbSNP:376273824
1027 1027 a, c dbSNP:772975589
1029 1029 c, g dbSNP:760242094
1031 1031 c, g dbSNP:768685160
1042 1042 c, t dbSNP:763314210
1043 1043 a, g dbSNP:535727568
1051 1051 a, g dbSNP:121918121
1055 1055 c, t dbSNP:752122561
1056 1056 a, g dbSNP:369089111
1073 1073 c, t dbSNP:149182247
1075 1075 c, t dbSNP:202089170
1080 1080 c, t dbSNP:750488020
1083 1083 a, g dbSNP:756177266
1092 1092 c, t dbSNP:780426452
1093 1093 a, g dbSNP:372024874
1096 1096 a, t dbSNP:754054724
1102 1102 a, g dbSNP:565529920
1108 1108 c, t dbSNP:778848120
1110 1110 g, t dbSNP:748136929
1116 1116 c, t dbSNP:771883010
1119 1119 c, t dbSNP:777718663
1123 1123 g, t dbSNP:746533943
1124 1124 a, g dbSNP:770409961
1126 1126 c, t dbSNP:776282236
1128 1128 c, g dbSNP:143333500
1135 1135 c, t dbSNP:376948691
1136 1136 a, g, t dbSNP:201403615
1137 1137 a, c dbSNP:557474309
1140 1140 c, t dbSNP:576049917
1142 1142 c, t dbSNP:200417925
1153 1153 -, ggact dbSNP:748432685
1157 1157 c, t dbSNP:766553585
1174 1174 c, t dbSNP:373883983
1179 1179 g, t dbSNP:751521824
1183 1183 a, g dbSNP:199990600
1184 1184 -, ccat dbSNP:772601101
1196 1196 a, g dbSNP:757160765
1206 1206 c, t dbSNP:375995048
1211 1211 a, t dbSNP:781055325
1212 1212 a, g dbSNP:200743419
1213 1213 g, t dbSNP:747380710
1227 1227 c, g, t dbSNP:771381012
1231 1231 c, t dbSNP:200508601
1232 1232 a, g dbSNP:769801107
1238 1238 g, t dbSNP:748027900
1253 1253 c, g dbSNP:775631493
1256 1256 -, agcttctgcc dbSNP:778207215
1256 1256 a, c dbSNP:550469546
1259 1259 g, t dbSNP:764385532
1265 1265 c, g dbSNP:774400027
1270 1270 g, t dbSNP:761620728
1274 1274 c, g, t dbSNP:767279880
1279 1279 c, t dbSNP:28371561
1280 1280 a, g dbSNP:189950019
1282 1282 a, g dbSNP:141571507
1292 1292 a, c dbSNP:754378932
1295 1295 c, t dbSNP:778657652
1296 1296 a, g dbSNP:752346076
1303 1303 c, t dbSNP:757742182
1304 1304 a, g dbSNP:781659959
1307 1307 -, ggcg dbSNP:747109235
1307 1307 c, t dbSNP:146305421
1308 1308 a, c, g dbSNP:28371562
1309 1309 a, g dbSNP:142878597
1311 1311 a, g dbSNP:181168274
1312 1312 a, g dbSNP:774608366
1314 1314 -, a dbSNP:771060895
1331 1331 c, t dbSNP:2228078
1334 1334 a, g dbSNP:139763309
1335 1335 c, g dbSNP:575480873
1344 1344 c, t dbSNP:369741931
1351 1351 c, t dbSNP:142228002
1352 1352 a, g dbSNP:766344455
1363 1363 a, c dbSNP:776509945
1367 1367 a, g dbSNP:759106817
1379 1379 a, g dbSNP:764629030
1386 1386 c, t dbSNP:374294592
1388 1388 a, t dbSNP:200055651
1389 1389 c, t dbSNP:185262577
1390 1390 a, g dbSNP:781726148
1424 1424 c, t dbSNP:35624572
1426 1426 a, t dbSNP:578006876
1451 1451 c, t dbSNP:190966223
1475 1475 c, t dbSNP:557566669
1485 1485 a, c dbSNP:2586
1559 1559 c, t dbSNP:28371563
1563 1563 c, t dbSNP:561615897
1574 1574 a, c dbSNP:28371564
1596 1596 a, g dbSNP:539807888

Target ORF information:

RefSeq Version XM_011515263
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens growth hormone releasing hormone receptor (GHRHR), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011515263

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGGTCCCTG GCACCCCCAG CCCCCTCCTG GGGAGAGGGA AGGAGTTGTG GCTAGAGAGT 
CTTGCTTGCC TCCCAGGGGC TGTGAAACGG GATTGTACTA TCACTGGCTG GTCTGAGCCC
TTTCCACCTT ACCCTGTGGC CTGCCCTGTG CCTCTGGAGC TGCTGGCTGA GGAGGAATCT
TACTTCTCCA CAGTGAAGAT TATCTACACC GTGGGCCATA GCATCTCTAT TGTAGCCCTC
TTCGTGGCCA TCACCATCCT GGTTGCTCTC AGGAGGCTCC ACTGCCCCCG GAACTACGTC
CACACCCAGC TGTTCACCAC TTTTATCCTC AAGGCGGGAG CTGTGTTCCT GAAGGATGCT
GCCCTTTTCC ACAGCGACGA CACTGACCAC TGCAGCTTCT CCACTGTTCT ATGCAAGGTC
TCTGTGGCCG CCTCCCATTT CGCCACCATG ACCAACTTCA GCTGGCTGTT GGCAGAAGCC
GTCTACCTGA ACTGCCTCCT GGCCTCCACC TCCCCCAGCT CAAGGAGAGC CTTCTGGTGG
CTGGTTCTCG CTGGCTGGGG GCTGCCCGTG CTCTTCACTG GCACGTGGGT GAGCTGCAAA
CTGGCCTTCG AGGACATCGC GTGCTGGGAC CTGGACGACA CCTCCCCCTA CTGGTGGATC
ATCAAAGGGC CCATTGTCCT CTCGGTCGGG GTGAACTTTG GGCTTTTTCT CAATATTATC
CGCATCCTGG TGAGGAAACT GGAGCCAGCT CAGGGCAGCC TCCATACCCA GTCTCAGTAT
TGGCGTCTCT CCAAGTCGAC ACTTTTCCTG ATCCCACTCT TTGGAATTCA CTACATCATC
TTCAACTTCC TGCCAGACAA TGCTGGCCTG GGCATCCGCC TCCCCCTGGA GCTGGGACTG
GGTTCCTTCC AGGGCTTCAT TGTTGCCATC CTCTACTGCT TCCTCAACCA AGAGGTGAGG
ACTGAGATCT CACGGAAGTG GCATGGCCAT GACCCTGAGC TTCTGCCAGC CTGGAGGACC
CGTGCTAAGT GGACCACGCC TTCCCGCTCG GCGGCAAAGG TGCTGACATC TATGTGCTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.