||ORF Nucleotide Sequence (Length: 1149bp)
||pcDNA3.1-C-(k)DYK or customized vector
|Tag on pcDNA3.1-C-(k)DYK
||C terminal DYKDDDDK tags
|ORF Insert Method
||CloneEZ® Seamless cloning technology
||Homo sapiens (human)
||gap junction alpha-1 protein
||REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from BP226987.1, BC026329.1,
AL139098.15 and AW664595.1.
This sequence is a reference standard in the RefSeqGene project.
On May 17, 2014 this sequence version replaced gi:122939163.
Summary: This gene is a member of the connexin gene family. The
encoded protein is a component of gap junctions, which are composed
of arrays of intercellular channels that provide a route for the
diffusion of low molecular weight materials from cell to cell. The
encoded protein is the major protein of gap junctions in the heart
that are thought to have a crucial role in the synchronized
contraction of the heart and in embryonic development. A related
intronless pseudogene has been mapped to chromosome 5. Mutations in
this gene have been associated with oculodentodigital dysplasia,
autosomal recessive craniometaphyseal dysplasia and heart
malformations. [provided by RefSeq, May 2014].
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
Transcript exon combination :: BP226987.1, X52947.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
COMPLETENESS: complete on the 3' end.