×

DISC1 cDNA ORF clone, Homo sapiens (human)

Gene Symbol DISC1
Entrez Gene ID 27185
Full Name disrupted in schizophrenia 1
Synonyms C1orf136, SCZD9
General protein information
Preferred Names
disrupted in schizophrenia 1 protein
Names
disrupted in schizophrenia 1 protein
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

1

1q42.1

Summary This gene encodes a protein with multiple coiled coil motifs which is located in the nucleus, cytoplasm and mitochondria. The protein is involved in neurite outgrowth and cortical development through its interaction with other proteins. This gene is disrupted in a t(1;11)(q42.1;q14.3) translocation which segregates with schizophrenia and related psychiatric disorders in a large Scottish family. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

605210

Disorder Html: {Schizophrenia, susceptibility to}, 604906 (3); {Schizoaffective

mRNA and Protein(s)

mRNA Protein Name
NM_001164556 NP_001158028 disrupted in schizophrenia 1 protein isoform t
NM_018662 NP_061132 disrupted in schizophrenia 1 protein isoform L
NM_001012957 NP_001012975 disrupted in schizophrenia 1 protein isoform Lv
NM_001012958 NP_001012976 disrupted in schizophrenia 1 protein isoform Es
NM_001012959 NP_001012977 disrupted in schizophrenia 1 protein isoform S
NM_001164537 NP_001158009 disrupted in schizophrenia 1 protein isoform a
NM_001164538 NP_001158010 disrupted in schizophrenia 1 protein isoform b
NM_001164539 NP_001158011 disrupted in schizophrenia 1 protein isoform c
NM_001164540 NP_001158012 disrupted in schizophrenia 1 protein isoform d
NM_001164541 NP_001158013 disrupted in schizophrenia 1 protein isoform e
NM_001164542 NP_001158014 disrupted in schizophrenia 1 protein isoform f
NM_001164544 NP_001158016 disrupted in schizophrenia 1 protein isoform g
NM_001164545 NP_001158017 disrupted in schizophrenia 1 protein isoform h
NM_001164546 NP_001158018 disrupted in schizophrenia 1 protein isoform i
NM_001164547 NP_001158019 disrupted in schizophrenia 1 protein isoform i
NM_001164548 NP_001158020 disrupted in schizophrenia 1 protein isoform k
NM_001164549 NP_001158021 disrupted in schizophrenia 1 protein isoform l
NM_001164550 NP_001158022 disrupted in schizophrenia 1 protein isoform m
NM_001164551 NP_001158023 disrupted in schizophrenia 1 protein isoform n
NM_001164552 NP_001158024 disrupted in schizophrenia 1 protein isoform o
NM_001164553 NP_001158025 disrupted in schizophrenia 1 protein isoform p
NM_001164554 NP_001158026 disrupted in schizophrenia 1 protein isoform q
NM_001164555 NP_001158027 disrupted in schizophrenia 1 protein isoform r


Homo sapiens (human) DISC1 NP_001158009.1
Pan troglodytes (chimpanzee) DISC1 XP_003308861.1
Macaca mulatta (Rhesus monkey) DISC1 NP_001107827.1
Canis lupus familiaris (dog) DISC1 XP_546088.3
Bos taurus (cattle) DISC1 XP_002698851.2
Mus musculus (house mouse) Disc1 NP_777279.2
Rattus norvegicus (Norway rat) Disc1 NP_783186.2
Gallus gallus (chicken) DISC1 XP_003641003.2


GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following DISC1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the DISC1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu25070 NM_001164556 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant t, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $188.30
$269.00
OHu24906 NM_018662 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant L, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $601.30
$859.00
OHu24960 NM_001012957 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant Lv, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $391.30
$559.00
OHu25035 NM_001012958 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant Es, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $223.30
$319.00
OHu24804 NM_001012959 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant S, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $482.30
$689.00
OHu25088 NM_001164537 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant a, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $629.30
$899.00
OHu24863 NM_001164538 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant b, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $391.30
$559.00
OHu24938 NM_001164539 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant c, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $531.30
$759.00
OHu24750 NM_001164540 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant d, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $391.30
$559.00
OHu24842 NM_001164541 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant e, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $489.30
$699.00
OHu25031 NM_001164542 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant f, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $391.30
$559.00
OHu24946 NM_001164544 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant g, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $384.30
$549.00
OHu24760 NM_001164545 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant h, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $342.30
$489.00
OHu24840 NM_001164546 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant i, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $307.30
$439.00
OHu24840 NM_001164547 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant j, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $307.30
$439.00
OHu25023 NM_001164548 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant k, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $321.30
$459.00
OHu24871 NM_001164549 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant l, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $321.30
$459.00
OHu24884 NM_001164550 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant m, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $251.30
$359.00
OHu24838 NM_001164551 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant n, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $251.30
$359.00
OHu24928 NM_001164552 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant o, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $223.30
$319.00
OHu24867 NM_001164553 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant p, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $223.30
$319.00
OHu24941 NM_001164554 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant q, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $69.30
$99.00
OHu24731 NM_001164555 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant r, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $209.30
$299.00
Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
5 or more Clone 50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu25070
Clone ID Related Accession (Same CDS sequence) NM_001164556
Accession Version NM_001164556.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 606bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 17-MAY-2014
Organism Homo sapiens (human)
Product disrupted in schizophrenia 1 protein isoform t
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from FJ804204.1. Transcript Variant: This variant (t) lacks four internal exons and multiple 3' exons but has an alternate 3' segment, as compared to variant L. The resulting isoform (t, also known as isoform 34) is the shortest, and has a distinct C-terminus, as compared to isoform L. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: FJ804204.1 [ECO:0000332] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
601
ATGCCAGGCG GGGGTCCTCA GGGCGCCCCA GCCGCCGCCG GCGGCGGCGG CGTGAGCCAC 
CGCGCAGCTG AGACGTTACA ACAAAGATTA GAAGACCTGG AACAAGAGAA AATCAGCCTG
CACTTTCAAC TTCCTTCAAG GCAGCCAGCT CTTAGCAGTT TCCTGGGTCA CCTGGCAGCA
CAAGTCCAGG CTGCCTTGCG CCGTGGGGCC ACTCAGCAGG CCAGCGGAGA TGACACCCAC
ACCCCACTGA GAATGGAGCC GAGGCTGTTG GAACCCACTG CTCAGGACAG CTTGCACGTG
TCCATCACGA GACGAGACTG GCTTCTTCAG GAAAAGCAGC AGCTACAGAA AGAAATCGAA
GCTCTCCAAG CAAGGATGTT TGTGCTGGAA GCCAAAGATC AACAGCTGAG AAGGGAAATA
GAGGAGCAAG AGCAGCAACT CCAGTGGCAG GGCTGCGACC TGACCCCACT GGTGGGCCAG
CTGTCCCTGG GTCAGCTGCA GGAGGTCAGC AAGGCCTTGC AGGACACCCT GGCCTCAGCC
GGTCAGATTC CCTTCCATGC AGAGCCACCG GAAACCATAA GGAGGAAACC ATTTCTGGAC
GGCTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001158028.1
CDS54..659
Exon (1)1..120
Gene:DISC1
Gene Synonym:
Exon (2)121..271
Gene:DISC1
Gene Synonym:
Exon (3)272..401
Gene:DISC1
Gene Synonym:
Exon (4)402..637
Gene:DISC1
Gene Synonym:
Exon (5)638..1553
Gene:DISC1
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001164556
Organism Homo sapiens (human)
Definition Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant t, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001164556

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
ATGCCAGGCG GGGGTCCTCA GGGCGCCCCA GCCGCCGCCG GCGGCGGCGG CGTGAGCCAC 
CGCGCAGCTG AGACGTTACA ACAAAGATTA GAAGACCTGG AACAAGAGAA AATCAGCCTG
CACTTTCAAC TTCCTTCAAG GCAGCCAGCT CTTAGCAGTT TCCTGGGTCA CCTGGCAGCA
CAAGTCCAGG CTGCCTTGCG CCGTGGGGCC ACTCAGCAGG CCAGCGGAGA TGACACCCAC
ACCCCACTGA GAATGGAGCC GAGGCTGTTG GAACCCACTG CTCAGGACAG CTTGCACGTG
TCCATCACGA GACGAGACTG GCTTCTTCAG GAAAAGCAGC AGCTACAGAA AGAAATCGAA
GCTCTCCAAG CAAGGATGTT TGTGCTGGAA GCCAAAGATC AACAGCTGAG AAGGGAAATA
GAGGAGCAAG AGCAGCAACT CCAGTGGCAG GGCTGCGACC TGACCCCACT GGTGGGCCAG
CTGTCCCTGG GTCAGCTGCA GGAGGTCAGC AAGGCCTTGC AGGACACCCT GGCCTCAGCC
GGTCAGATTC CCTTCCATGC AGAGCCACCG GAAACCATAA GGAGGAAACC ATTTCTGGAC
GGCTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu24906
Clone ID Related Accession (Same CDS sequence) NM_018662
Accession Version NM_018662.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2565bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product disrupted in schizophrenia 1 protein isoform L
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF222980.1, AJ506178.1, AB007926.1 and AI075754.1. This sequence is a reference standard in the RefSeqGene project. On Mar 24, 2005 this sequence version replaced gi:11037064. Transcript Variant: This variant (L) encodes isoform L, also known as the 'Long' isoform. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF222980.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2152798 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
ATGCCAGGCG GGGGTCCTCA GGGCGCCCCA GCCGCCGCCG GCGGCGGCGG CGTGAGCCAC 
CGCGCAGGCA GCCGGGATTG CTTACCACCT GCAGCGTGCT TTCGGAGGCG GCGGCTGGCA
CGGAGGCCGG GCTACATGAG AAGCTCGACA GGGCCTGGGA TCGGGTTCCT TTCCCCAGCA
GTGGGCACAC TGTTCCGGTT CCCAGGAGGG GTGTCTGGCG AGGAGTCCCA CCACTCGGAG
TCCAGGGCCA GACAGTGTGG CCTTGACTCG AGAGGCCTCT TGGTCCGGAG CCCTGTTTCC
AAGAGTGCAG CAGCCCCTAC TGTGACCTCT GTGAGAGGAA CCTCGGCGCA CTTTGGGATT
CAGCTCAGAG GTGGCACCAG ATTGCCTGAC AGGCTTAGCT GGCCGTGTGG CCCTGGGAGT
GCTGGGTGGC AGCAAGAGTT TGCAGCCATG GATAGTTCTG AGACCCTGGA CGCCAGCTGG
GAGGCAGCCT GCAGCGATGG AGCAAGGCGT GTCCGGGCAG CAGGCTCTCT GCCATCAGCA
GAGTTGAGTA GCAACAGCTG CAGCCCTGGC TGTGGCCCTG AGGTCCCCCC AACCCCTCCT
GGCTCTCACA GTGCCTTTAC CTCAAGCTTT AGCTTTATTC GGCTCTCGCT TGGCTCTGCC
GGGGAACGTG GAGAAGCAGA AGGCTGCCCA CCATCCAGAG AGGCTGAGTC CCATTGCCAG
AGCCCCCAGG AGATGGGAGC CAAAGCTGCC AGCTTGGACG GGCCTCACGA GGACCCGCGA
TGTCTCTCTC GGCCCTTCAG TCTCTTGGCT ACACGGGTCT CTGCAGACTT GGCCCAGGCC
GCAAGGAACA GCTCCAGGCC AGAGCGTGAC ATGCATTCTT TACCAGACAT GGACCCTGGC
TCCTCCAGTT CTCTGGATCC CTCACTGGCT GGCTGTGGTG GTGATGGGAG CAGCGGCTCA
GGGGATGCCC ACTCTTGGGA CACCCTGCTC AGGAAATGGG AGCCAGTGCT GCGGGACTGC
CTGCTGAGAA ACCGGAGGCA GATGGAGGTA ATATCCTTAA GATTAAAACT TCAGAAACTT
CAGGAAGATG CAGTTGAGAA TGATGATTAT GATAAAGCTG AGACGTTACA ACAAAGATTA
GAAGACCTGG AACAAGAGAA AATCAGCCTG CACTTTCAAC TTCCTTCAAG GCAGCCAGCT
CTTAGCAGTT TCCTGGGTCA CCTGGCAGCA CAAGTCCAGG CTGCCTTGCG CCGTGGGGCC
ACTCAGCAGG CCAGCGGAGA TGACACCCAC ACCCCACTGA GAATGGAGCC GAGGCTGTTG
GAACCCACTG CTCAGGACAG CTTGCACGTG TCCATCACGA GACGAGACTG GCTTCTTCAG
GAAAAGCAGC AGCTACAGAA AGAAATCGAA GCTCTCCAAG CAAGGATGTT TGTGCTGGAA
GCCAAAGATC AACAGCTGAG AAGGGAAATA GAGGAGCAAG AGCAGCAACT CCAGTGGCAG
GGCTGCGACC TGACCCCACT GGTGGGCCAG CTGTCCCTGG GTCAGCTGCA GGAGGTCAGC
AAGGCCTTGC AGGACACCCT GGCCTCAGCC GGTCAGATTC CCTTCCATGC AGAGCCACCG
GAAACCATAA GGAGCCTCCA GGAAAGAATA AAATCCCTCA ACTTGTCACT TAAAGAAATC
ACTACTAAGG TGTGTATGAG TGAGAAATTC TGCAGCACCC TGAGGAAGAA AGTTAACGAT
ATTGAAACCC AACTACCAGC CTTGCTTGAA GCCAAAATGC ATGCCATATC AGGAAACCAT
TTCTGGACGG CTAAAGACCT CACCGAGGAG ATTAGATCAT TAACATCAGA GAGAGAAGGG
CTGGAGGGAC TCCTCAGCAA GCTGTTGGTG TTGAGTTCCA GGAATGTCAA AAAGCTGGGA
AGTGTTAAAG AAGATTACAA CAGACTGAGA AGAGAAGTGG AGCACCAGGA GACTGCCTAT
GAAACAAGTG TGAAGGAAAA TACTATGAAG TACATGGAAA CACTTAAGAA TAAACTGTGC
AGCTGCAAGT GTCCACTGCT TGGGAAAGTG TGGGAAGCTG ACTTGGAAGC TTGTCGATTG
CTTATCCAGA GCCTACAGCT CCAGGAAGCC AGGGGAAGCC TGTCTGTAGA AGATGAGAGG
CAGATGGATG ACTTAGAGGG AGCTGCTCCT CCTATTCCCC CCAGGCTCCA CTCCGAGGAT
AAAAGGAAGA CCCCTTTGAA GGTATTGGAA GAATGGAAGA CTCACCTCAT CCCCTCTCTG
CACTGTGCTG GAGGTGAACA GAAAGAGGAA TCTTACATCC TTTCTGCAGA ACTTGGAGAA
AAGTGTGAAG ACATAGGCAA GAAGCTATTG TACTTGGAAG ATCAACTTCA CACAGCAATC
CACAGTCATG ATGAAGATCT CATTCAGTCT CTCAGGAGGG AGCTCCAGAT GGTGAAGGAA
ACTCTGCAGG CCATGATCCT GCAGCTCCAG CCAGCAAAGG AGGCGGGAGA AAGAGAAGCT
GCAGCTTCCT GCATGACAGC TGGTGTCCAC GAAGCACAAG CCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_061132.2
CDS54..2618
Misc Feature(1)54..929(+)
Misc Feature(2)930..2141(+)
Misc Feature(3)1062..2087(+)
Misc Feature(4)1371..1844(+)
Misc Feature(5)1389..2615(+)
Misc Feature(6)1632..2579(+)
Misc Feature(7)1845..2615(+)
Misc Feature(8)2232..2615(+)
Misc Feature(9)2457..2558(+)
Exon (1)1..120
Gene:DISC1
Gene Synonym:
Exon (2)121..1100
Gene:DISC1
Gene Synonym:
Exon (3)1101..1170
Gene:DISC1
Gene Synonym:
Exon (4)1171..1321
Gene:DISC1
Gene Synonym:
Exon (5)1322..1451
Gene:DISC1
Gene Synonym:
Exon (6)1452..1687
Gene:DISC1
Gene Synonym:
Exon (7)1688..1742
Gene:DISC1
Gene Synonym:
Exon (8)1743..1845
Gene:DISC1
Gene Synonym:
Exon (9)1846..2034
Gene:DISC1
Gene Synonym:
Exon (10)2035..2095
Gene:DISC1
Gene Synonym:
Exon (11)2096..2360
Gene:DISC1
Gene Synonym:
Exon (12)2361..2478
Gene:DISC1
Gene Synonym:
Exon (13)2479..7059
Gene:DISC1
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_018662
Organism Homo sapiens (human)
Definition Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant L, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_018662

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
ATGCCAGGCG GGGGTCCTCA GGGCGCCCCA GCCGCCGCCG GCGGCGGCGG CGTGAGCCAC 
CGCGCAGGCA GCCGGGATTG CTTACCACCT GCAGCGTGCT TTCGGAGGCG GCGGCTGGCA
CGGAGGCCGG GCTACATGAG AAGCTCGACA GGGCCTGGGA TCGGGTTCCT TTCCCCAGCA
GTGGGCACAC TGTTCCGGTT CCCAGGAGGG GTGTCTGGCG AGGAGTCCCA CCACTCGGAG
TCCAGGGCCA GACAGTGTGG CCTTGACTCG AGAGGCCTCT TGGTCCGGAG CCCTGTTTCC
AAGAGTGCAG CAGCCCCTAC TGTGACCTCT GTGAGAGGAA CCTCGGCGCA CTTTGGGATT
CAGCTCAGAG GTGGCACCAG ATTGCCTGAC AGGCTTAGCT GGCCGTGTGG CCCTGGGAGT
GCTGGGTGGC AGCAAGAGTT TGCAGCCATG GATAGTTCTG AGACCCTGGA CGCCAGCTGG
GAGGCAGCCT GCAGCGATGG AGCAAGGCGT GTCCGGGCAG CAGGCTCTCT GCCATCAGCA
GAGTTGAGTA GCAACAGCTG CAGCCCTGGC TGTGGCCCTG AGGTCCCCCC AACCCCTCCT
GGCTCTCACA GTGCCTTTAC CTCAAGCTTT AGCTTTATTC GGCTCTCGCT TGGCTCTGCC
GGGGAACGTG GAGAAGCAGA AGGCTGCCCA CCATCCAGAG AGGCTGAGTC CCATTGCCAG
AGCCCCCAGG AGATGGGAGC CAAAGCTGCC AGCTTGGACG GGCCTCACGA GGACCCGCGA
TGTCTCTCTC GGCCCTTCAG TCTCTTGGCT ACACGGGTCT CTGCAGACTT GGCCCAGGCC
GCAAGGAACA GCTCCAGGCC AGAGCGTGAC ATGCATTCTT TACCAGACAT GGACCCTGGC
TCCTCCAGTT CTCTGGATCC CTCACTGGCT GGCTGTGGTG GTGATGGGAG CAGCGGCTCA
GGGGATGCCC ACTCTTGGGA CACCCTGCTC AGGAAATGGG AGCCAGTGCT GCGGGACTGC
CTGCTGAGAA ACCGGAGGCA GATGGAGGTA ATATCCTTAA GATTAAAACT TCAGAAACTT
CAGGAAGATG CAGTTGAGAA TGATGATTAT GATAAAGCTG AGACGTTACA ACAAAGATTA
GAAGACCTGG AACAAGAGAA AATCAGCCTG CACTTTCAAC TTCCTTCAAG GCAGCCAGCT
CTTAGCAGTT TCCTGGGTCA CCTGGCAGCA CAAGTCCAGG CTGCCTTGCG CCGTGGGGCC
ACTCAGCAGG CCAGCGGAGA TGACACCCAC ACCCCACTGA GAATGGAGCC GAGGCTGTTG
GAACCCACTG CTCAGGACAG CTTGCACGTG TCCATCACGA GACGAGACTG GCTTCTTCAG
GAAAAGCAGC AGCTACAGAA AGAAATCGAA GCTCTCCAAG CAAGGATGTT TGTGCTGGAA
GCCAAAGATC AACAGCTGAG AAGGGAAATA GAGGAGCAAG AGCAGCAACT CCAGTGGCAG
GGCTGCGACC TGACCCCACT GGTGGGCCAG CTGTCCCTGG GTCAGCTGCA GGAGGTCAGC
AAGGCCTTGC AGGACACCCT GGCCTCAGCC GGTCAGATTC CCTTCCATGC AGAGCCACCG
GAAACCATAA GGAGCCTCCA GGAAAGAATA AAATCCCTCA ACTTGTCACT TAAAGAAATC
ACTACTAAGG TGTGTATGAG TGAGAAATTC TGCAGCACCC TGAGGAAGAA AGTTAACGAT
ATTGAAACCC AACTACCAGC CTTGCTTGAA GCCAAAATGC ATGCCATATC AGGAAACCAT
TTCTGGACGG CTAAAGACCT CACCGAGGAG ATTAGATCAT TAACATCAGA GAGAGAAGGG
CTGGAGGGAC TCCTCAGCAA GCTGTTGGTG TTGAGTTCCA GGAATGTCAA AAAGCTGGGA
AGTGTTAAAG AAGATTACAA CAGACTGAGA AGAGAAGTGG AGCACCAGGA GACTGCCTAT
GAAACAAGTG TGAAGGAAAA TACTATGAAG TACATGGAAA CACTTAAGAA TAAACTGTGC
AGCTGCAAGT GTCCACTGCT TGGGAAAGTG TGGGAAGCTG ACTTGGAAGC TTGTCGATTG
CTTATCCAGA GCCTACAGCT CCAGGAAGCC AGGGGAAGCC TGTCTGTAGA AGATGAGAGG
CAGATGGATG ACTTAGAGGG AGCTGCTCCT CCTATTCCCC CCAGGCTCCA CTCCGAGGAT
AAAAGGAAGA CCCCTTTGAA GGTATTGGAA GAATGGAAGA CTCACCTCAT CCCCTCTCTG
CACTGTGCTG GAGGTGAACA GAAAGAGGAA TCTTACATCC TTTCTGCAGA ACTTGGAGAA
AAGTGTGAAG ACATAGGCAA GAAGCTATTG TACTTGGAAG ATCAACTTCA CACAGCAATC
CACAGTCATG ATGAAGATCT CATTCAGTCT CTCAGGAGGG AGCTCCAGAT GGTGAAGGAA
ACTCTGCAGG CCATGATCCT GCAGCTCCAG CCAGCAAAGG AGGCGGGAGA AAGAGAAGCT
GCAGCTTCCT GCATGACAGC TGGTGTCCAC GAAGCACAAG CCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu24960
Clone ID Related Accession (Same CDS sequence) NM_001012957
Accession Version NM_001012957.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2499bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product disrupted in schizophrenia 1 protein isoform Lv
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AJ506177.1, AB007926.1, AJ506178.1 and AI075754.1. Transcript Variant: This variant (Lv) has an alternate splice site in the 3' coding region, as compared to variant L. The reading frame is not changed, and the resulting isoform (Lv, also known as the 'Long variant' isoform) lacks an internal segment, as compared to isoform L. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC151225.1, AB007926.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2152798, SAMEA2155751 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
ATGCCAGGCG GGGGTCCTCA GGGCGCCCCA GCCGCCGCCG GCGGCGGCGG CGTGAGCCAC 
CGCGCAGGCA GCCGGGATTG CTTACCACCT GCAGCGTGCT TTCGGAGGCG GCGGCTGGCA
CGGAGGCCGG GCTACATGAG AAGCTCGACA GGGCCTGGGA TCGGGTTCCT TTCCCCAGCA
GTGGGCACAC TGTTCCGGTT CCCAGGAGGG GTGTCTGGCG AGGAGTCCCA CCACTCGGAG
TCCAGGGCCA GACAGTGTGG CCTTGACTCG AGAGGCCTCT TGGTCCGGAG CCCTGTTTCC
AAGAGTGCAG CAGCCCCTAC TGTGACCTCT GTGAGAGGAA CCTCGGCGCA CTTTGGGATT
CAGCTCAGAG GTGGCACCAG ATTGCCTGAC AGGCTTAGCT GGCCGTGTGG CCCTGGGAGT
GCTGGGTGGC AGCAAGAGTT TGCAGCCATG GATAGTTCTG AGACCCTGGA CGCCAGCTGG
GAGGCAGCCT GCAGCGATGG AGCAAGGCGT GTCCGGGCAG CAGGCTCTCT GCCATCAGCA
GAGTTGAGTA GCAACAGCTG CAGCCCTGGC TGTGGCCCTG AGGTCCCCCC AACCCCTCCT
GGCTCTCACA GTGCCTTTAC CTCAAGCTTT AGCTTTATTC GGCTCTCGCT TGGCTCTGCC
GGGGAACGTG GAGAAGCAGA AGGCTGCCCA CCATCCAGAG AGGCTGAGTC CCATTGCCAG
AGCCCCCAGG AGATGGGAGC CAAAGCTGCC AGCTTGGACG GGCCTCACGA GGACCCGCGA
TGTCTCTCTC GGCCCTTCAG TCTCTTGGCT ACACGGGTCT CTGCAGACTT GGCCCAGGCC
GCAAGGAACA GCTCCAGGCC AGAGCGTGAC ATGCATTCTT TACCAGACAT GGACCCTGGC
TCCTCCAGTT CTCTGGATCC CTCACTGGCT GGCTGTGGTG GTGATGGGAG CAGCGGCTCA
GGGGATGCCC ACTCTTGGGA CACCCTGCTC AGGAAATGGG AGCCAGTGCT GCGGGACTGC
CTGCTGAGAA ACCGGAGGCA GATGGAGGTA ATATCCTTAA GATTAAAACT TCAGAAACTT
CAGGAAGATG CAGTTGAGAA TGATGATTAT GATAAAGCTG AGACGTTACA ACAAAGATTA
GAAGACCTGG AACAAGAGAA AATCAGCCTG CACTTTCAAC TTCCTTCAAG GCAGCCAGCT
CTTAGCAGTT TCCTGGGTCA CCTGGCAGCA CAAGTCCAGG CTGCCTTGCG CCGTGGGGCC
ACTCAGCAGG CCAGCGGAGA TGACACCCAC ACCCCACTGA GAATGGAGCC GAGGCTGTTG
GAACCCACTG CTCAGGACAG CTTGCACGTG TCCATCACGA GACGAGACTG GCTTCTTCAG
GAAAAGCAGC AGCTACAGAA AGAAATCGAA GCTCTCCAAG CAAGGATGTT TGTGCTGGAA
GCCAAAGATC AACAGCTGAG AAGGGAAATA GAGGAGCAAG AGCAGCAACT CCAGTGGCAG
GGCTGCGACC TGACCCCACT GGTGGGCCAG CTGTCCCTGG GTCAGCTGCA GGAGGTCAGC
AAGGCCTTGC AGGACACCCT GGCCTCAGCC GGTCAGATTC CCTTCCATGC AGAGCCACCG
GAAACCATAA GGAGCCTCCA GGAAAGAATA AAATCCCTCA ACTTGTCACT TAAAGAAATC
ACTACTAAGG TGTGTATGAG TGAGAAATTC TGCAGCACCC TGAGGAAGAA AGTTAACGAT
ATTGAAACCC AACTACCAGC CTTGCTTGAA GCCAAAATGC ATGCCATATC AGGAAACCAT
TTCTGGACGG CTAAAGACCT CACCGAGGAG ATTAGATCAT TAACATCAGA GAGAGAAGGG
CTGGAGGGAC TCCTCAGCAA GCTGTTGGTG TTGAGTTCCA GGAATGTCAA AAAGCTGGGA
AGTGTTAAAG AAGATTACAA CAGACTGAGA AGAGAAGTGG AGCACCAGGA GACTGCCTAT
GAAACAAGTG TGAAGGAAAA TACTATGAAG TACATGGAAA CACTTAAGAA TAAACTGTGC
AGCTGCAAGT GTCCACTGCT TGGGAAAGTG TGGGAAGCTG ACTTGGAAGC TTGTCGATTG
CTTATCCAGA GCCTACAGCT CCAGGAAGCC AGGGGAAGCC TGTCTGTAGA AGATGAGAGG
CAGATGGATG ACTTAGAGGG AGCTGCTCCT CCTATTCCCC CCAGGCTCCA CTCCGAGGAT
AAAAGGAAGA CCCCTTTGAA GGAATCTTAC ATCCTTTCTG CAGAACTTGG AGAAAAGTGT
GAAGACATAG GCAAGAAGCT ATTGTACTTG GAAGATCAAC TTCACACAGC AATCCACAGT
CATGATGAAG ATCTCATTCA GTCTCTCAGG AGGGAGCTCC AGATGGTGAA GGAAACTCTG
CAGGCCATGA TCCTGCAGCT CCAGCCAGCA AAGGAGGCGG GAGAAAGAGA AGCTGCAGCT
TCCTGCATGA CAGCTGGTGT CCACGAAGCA CAAGCCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001012975.1
CDS54..2552
Misc Feature(1)1425..2447(+)
Exon (1)1..120
Gene:DISC1
Gene Synonym:
Exon (2)121..1100
Gene:DISC1
Gene Synonym:
Exon (3)1101..1170
Gene:DISC1
Gene Synonym:
Exon (4)1171..1321
Gene:DISC1
Gene Synonym:
Exon (5)1322..1451
Gene:DISC1
Gene Synonym:
Exon (6)1452..1687
Gene:DISC1
Gene Synonym:
Exon (7)1688..1742
Gene:DISC1
Gene Synonym:
Exon (8)1743..1845
Gene:DISC1
Gene Synonym:
Exon (9)1846..2034
Gene:DISC1
Gene Synonym:
Exon (10)2035..2095
Gene:DISC1
Gene Synonym:
Exon (11)2096..2294
Gene:DISC1
Gene Synonym:
Exon (12)2295..2412
Gene:DISC1
Gene Synonym:
Exon (13)2413..6993
Gene:DISC1
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001012957
Organism Homo sapiens (human)
Definition Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant Lv, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001012957

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
ATGCCAGGCG GGGGTCCTCA GGGCGCCCCA GCCGCCGCCG GCGGCGGCGG CGTGAGCCAC 
CGCGCAGGCA GCCGGGATTG CTTACCACCT GCAGCGTGCT TTCGGAGGCG GCGGCTGGCA
CGGAGGCCGG GCTACATGAG AAGCTCGACA GGGCCTGGGA TCGGGTTCCT TTCCCCAGCA
GTGGGCACAC TGTTCCGGTT CCCAGGAGGG GTGTCTGGCG AGGAGTCCCA CCACTCGGAG
TCCAGGGCCA GACAGTGTGG CCTTGACTCG AGAGGCCTCT TGGTCCGGAG CCCTGTTTCC
AAGAGTGCAG CAGCCCCTAC TGTGACCTCT GTGAGAGGAA CCTCGGCGCA CTTTGGGATT
CAGCTCAGAG GTGGCACCAG ATTGCCTGAC AGGCTTAGCT GGCCGTGTGG CCCTGGGAGT
GCTGGGTGGC AGCAAGAGTT TGCAGCCATG GATAGTTCTG AGACCCTGGA CGCCAGCTGG
GAGGCAGCCT GCAGCGATGG AGCAAGGCGT GTCCGGGCAG CAGGCTCTCT GCCATCAGCA
GAGTTGAGTA GCAACAGCTG CAGCCCTGGC TGTGGCCCTG AGGTCCCCCC AACCCCTCCT
GGCTCTCACA GTGCCTTTAC CTCAAGCTTT AGCTTTATTC GGCTCTCGCT TGGCTCTGCC
GGGGAACGTG GAGAAGCAGA AGGCTGCCCA CCATCCAGAG AGGCTGAGTC CCATTGCCAG
AGCCCCCAGG AGATGGGAGC CAAAGCTGCC AGCTTGGACG GGCCTCACGA GGACCCGCGA
TGTCTCTCTC GGCCCTTCAG TCTCTTGGCT ACACGGGTCT CTGCAGACTT GGCCCAGGCC
GCAAGGAACA GCTCCAGGCC AGAGCGTGAC ATGCATTCTT TACCAGACAT GGACCCTGGC
TCCTCCAGTT CTCTGGATCC CTCACTGGCT GGCTGTGGTG GTGATGGGAG CAGCGGCTCA
GGGGATGCCC ACTCTTGGGA CACCCTGCTC AGGAAATGGG AGCCAGTGCT GCGGGACTGC
CTGCTGAGAA ACCGGAGGCA GATGGAGGTA ATATCCTTAA GATTAAAACT TCAGAAACTT
CAGGAAGATG CAGTTGAGAA TGATGATTAT GATAAAGCTG AGACGTTACA ACAAAGATTA
GAAGACCTGG AACAAGAGAA AATCAGCCTG CACTTTCAAC TTCCTTCAAG GCAGCCAGCT
CTTAGCAGTT TCCTGGGTCA CCTGGCAGCA CAAGTCCAGG CTGCCTTGCG CCGTGGGGCC
ACTCAGCAGG CCAGCGGAGA TGACACCCAC ACCCCACTGA GAATGGAGCC GAGGCTGTTG
GAACCCACTG CTCAGGACAG CTTGCACGTG TCCATCACGA GACGAGACTG GCTTCTTCAG
GAAAAGCAGC AGCTACAGAA AGAAATCGAA GCTCTCCAAG CAAGGATGTT TGTGCTGGAA
GCCAAAGATC AACAGCTGAG AAGGGAAATA GAGGAGCAAG AGCAGCAACT CCAGTGGCAG
GGCTGCGACC TGACCCCACT GGTGGGCCAG CTGTCCCTGG GTCAGCTGCA GGAGGTCAGC
AAGGCCTTGC AGGACACCCT GGCCTCAGCC GGTCAGATTC CCTTCCATGC AGAGCCACCG
GAAACCATAA GGAGCCTCCA GGAAAGAATA AAATCCCTCA ACTTGTCACT TAAAGAAATC
ACTACTAAGG TGTGTATGAG TGAGAAATTC TGCAGCACCC TGAGGAAGAA AGTTAACGAT
ATTGAAACCC AACTACCAGC CTTGCTTGAA GCCAAAATGC ATGCCATATC AGGAAACCAT
TTCTGGACGG CTAAAGACCT CACCGAGGAG ATTAGATCAT TAACATCAGA GAGAGAAGGG
CTGGAGGGAC TCCTCAGCAA GCTGTTGGTG TTGAGTTCCA GGAATGTCAA AAAGCTGGGA
AGTGTTAAAG AAGATTACAA CAGACTGAGA AGAGAAGTGG AGCACCAGGA GACTGCCTAT
GAAACAAGTG TGAAGGAAAA TACTATGAAG TACATGGAAA CACTTAAGAA TAAACTGTGC
AGCTGCAAGT GTCCACTGCT TGGGAAAGTG TGGGAAGCTG ACTTGGAAGC TTGTCGATTG
CTTATCCAGA GCCTACAGCT CCAGGAAGCC AGGGGAAGCC TGTCTGTAGA AGATGAGAGG
CAGATGGATG ACTTAGAGGG AGCTGCTCCT CCTATTCCCC CCAGGCTCCA CTCCGAGGAT
AAAAGGAAGA CCCCTTTGAA GGAATCTTAC ATCCTTTCTG CAGAACTTGG AGAAAAGTGT
GAAGACATAG GCAAGAAGCT ATTGTACTTG GAAGATCAAC TTCACACAGC AATCCACAGT
CATGATGAAG ATCTCATTCA GTCTCTCAGG AGGGAGCTCC AGATGGTGAA GGAAACTCTG
CAGGCCATGA TCCTGCAGCT CCAGCCAGCA AAGGAGGCGG GAGAAAGAGA AGCTGCAGCT
TCCTGCATGA CAGCTGGTGT CCACGAAGCA CAAGCCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu25035
Clone ID Related Accession (Same CDS sequence) NM_001012958
Accession Version NM_001012958.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1110bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product disrupted in schizophrenia 1 protein isoform Es
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AJ506178.1. Transcript Variant: This variant (Es) lacks multiple 3' exons but has an alternate 3' exon, as compared to variant L. The resulting isoform (Es, also known as the 'Extremely short' isoform) is much shorter and has a distinct C-terminus, as compared to isoform L. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AJ506178.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1968540, SAMEA2142348 [ECO:0000350] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
ATGCCAGGCG GGGGTCCTCA GGGCGCCCCA GCCGCCGCCG GCGGCGGCGG CGTGAGCCAC 
CGCGCAGGCA GCCGGGATTG CTTACCACCT GCAGCGTGCT TTCGGAGGCG GCGGCTGGCA
CGGAGGCCGG GCTACATGAG AAGCTCGACA GGGCCTGGGA TCGGGTTCCT TTCCCCAGCA
GTGGGCACAC TGTTCCGGTT CCCAGGAGGG GTGTCTGGCG AGGAGTCCCA CCACTCGGAG
TCCAGGGCCA GACAGTGTGG CCTTGACTCG AGAGGCCTCT TGGTCCGGAG CCCTGTTTCC
AAGAGTGCAG CAGCCCCTAC TGTGACCTCT GTGAGAGGAA CCTCGGCGCA CTTTGGGATT
CAGCTCAGAG GTGGCACCAG ATTGCCTGAC AGGCTTAGCT GGCCGTGTGG CCCTGGGAGT
GCTGGGTGGC AGCAAGAGTT TGCAGCCATG GATAGTTCTG AGACCCTGGA CGCCAGCTGG
GAGGCAGCCT GCAGCGATGG AGCAAGGCGT GTCCGGGCAG CAGGCTCTCT GCCATCAGCA
GAGTTGAGTA GCAACAGCTG CAGCCCTGGC TGTGGCCCTG AGGTCCCCCC AACCCCTCCT
GGCTCTCACA GTGCCTTTAC CTCAAGCTTT AGCTTTATTC GGCTCTCGCT TGGCTCTGCC
GGGGAACGTG GAGAAGCAGA AGGCTGCCCA CCATCCAGAG AGGCTGAGTC CCATTGCCAG
AGCCCCCAGG AGATGGGAGC CAAAGCTGCC AGCTTGGACG GGCCTCACGA GGACCCGCGA
TGTCTCTCTC GGCCCTTCAG TCTCTTGGCT ACACGGGTCT CTGCAGACTT GGCCCAGGCC
GCAAGGAACA GCTCCAGGCC AGAGCGTGAC ATGCATTCTT TACCAGACAT GGACCCTGGC
TCCTCCAGTT CTCTGGATCC CTCACTGGCT GGCTGTGGTG GTGATGGGAG CAGCGGCTCA
GGGGATGCCC ACTCTTGGGA CACCCTGCTC AGGAAATGGG AGCCAGTGCT GCGGGACTGC
CTGCTGAGAA ACCGGAGGCA GATGGAGCTG GAACCAATTG CTTTGGATCC ACCATGGAAG
CCTCGACATC CTGAACCAAA CTCCTATTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001012976.1
CDS54..1163
Misc Feature(1)54..929(+)
Exon (1)1..120
Gene:DISC1
Gene Synonym:
Exon (2)121..1100
Gene:DISC1
Gene Synonym:
Exon (3)1101..2636
Gene:DISC1
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001012958
Organism Homo sapiens (human)
Definition Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant Es, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001012958

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
ATGCCAGGCG GGGGTCCTCA GGGCGCCCCA GCCGCCGCCG GCGGCGGCGG CGTGAGCCAC 
CGCGCAGGCA GCCGGGATTG CTTACCACCT GCAGCGTGCT TTCGGAGGCG GCGGCTGGCA
CGGAGGCCGG GCTACATGAG AAGCTCGACA GGGCCTGGGA TCGGGTTCCT TTCCCCAGCA
GTGGGCACAC TGTTCCGGTT CCCAGGAGGG GTGTCTGGCG AGGAGTCCCA CCACTCGGAG
TCCAGGGCCA GACAGTGTGG CCTTGACTCG AGAGGCCTCT TGGTCCGGAG CCCTGTTTCC
AAGAGTGCAG CAGCCCCTAC TGTGACCTCT GTGAGAGGAA CCTCGGCGCA CTTTGGGATT
CAGCTCAGAG GTGGCACCAG ATTGCCTGAC AGGCTTAGCT GGCCGTGTGG CCCTGGGAGT
GCTGGGTGGC AGCAAGAGTT TGCAGCCATG GATAGTTCTG AGACCCTGGA CGCCAGCTGG
GAGGCAGCCT GCAGCGATGG AGCAAGGCGT GTCCGGGCAG CAGGCTCTCT GCCATCAGCA
GAGTTGAGTA GCAACAGCTG CAGCCCTGGC TGTGGCCCTG AGGTCCCCCC AACCCCTCCT
GGCTCTCACA GTGCCTTTAC CTCAAGCTTT AGCTTTATTC GGCTCTCGCT TGGCTCTGCC
GGGGAACGTG GAGAAGCAGA AGGCTGCCCA CCATCCAGAG AGGCTGAGTC CCATTGCCAG
AGCCCCCAGG AGATGGGAGC CAAAGCTGCC AGCTTGGACG GGCCTCACGA GGACCCGCGA
TGTCTCTCTC GGCCCTTCAG TCTCTTGGCT ACACGGGTCT CTGCAGACTT GGCCCAGGCC
GCAAGGAACA GCTCCAGGCC AGAGCGTGAC ATGCATTCTT TACCAGACAT GGACCCTGGC
TCCTCCAGTT CTCTGGATCC CTCACTGGCT GGCTGTGGTG GTGATGGGAG CAGCGGCTCA
GGGGATGCCC ACTCTTGGGA CACCCTGCTC AGGAAATGGG AGCCAGTGCT GCGGGACTGC
CTGCTGAGAA ACCGGAGGCA GATGGAGCTG GAACCAATTG CTTTGGATCC ACCATGGAAG
CCTCGACATC CTGAACCAAA CTCCTATTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu24804
Clone ID Related Accession (Same CDS sequence) NM_001012959
Accession Version NM_001012959.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2037bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product disrupted in schizophrenia 1 protein isoform S
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AJ506177.1, AJ506178.1 and BC038954.1. Transcript Variant: This variant (S) lacks several 3' exons but has an alternate 3' exon, as compared to variant L. The resulting isoform (S, also known as the 'Short' isoform) is shorter and has a distinct C-terminus, as compared to isoform L. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AJ506177.1, BC038954.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
ATGCCAGGCG GGGGTCCTCA GGGCGCCCCA GCCGCCGCCG GCGGCGGCGG CGTGAGCCAC 
CGCGCAGGCA GCCGGGATTG CTTACCACCT GCAGCGTGCT TTCGGAGGCG GCGGCTGGCA
CGGAGGCCGG GCTACATGAG AAGCTCGACA GGGCCTGGGA TCGGGTTCCT TTCCCCAGCA
GTGGGCACAC TGTTCCGGTT CCCAGGAGGG GTGTCTGGCG AGGAGTCCCA CCACTCGGAG
TCCAGGGCCA GACAGTGTGG CCTTGACTCG AGAGGCCTCT TGGTCCGGAG CCCTGTTTCC
AAGAGTGCAG CAGCCCCTAC TGTGACCTCT GTGAGAGGAA CCTCGGCGCA CTTTGGGATT
CAGCTCAGAG GTGGCACCAG ATTGCCTGAC AGGCTTAGCT GGCCGTGTGG CCCTGGGAGT
GCTGGGTGGC AGCAAGAGTT TGCAGCCATG GATAGTTCTG AGACCCTGGA CGCCAGCTGG
GAGGCAGCCT GCAGCGATGG AGCAAGGCGT GTCCGGGCAG CAGGCTCTCT GCCATCAGCA
GAGTTGAGTA GCAACAGCTG CAGCCCTGGC TGTGGCCCTG AGGTCCCCCC AACCCCTCCT
GGCTCTCACA GTGCCTTTAC CTCAAGCTTT AGCTTTATTC GGCTCTCGCT TGGCTCTGCC
GGGGAACGTG GAGAAGCAGA AGGCTGCCCA CCATCCAGAG AGGCTGAGTC CCATTGCCAG
AGCCCCCAGG AGATGGGAGC CAAAGCTGCC AGCTTGGACG GGCCTCACGA GGACCCGCGA
TGTCTCTCTC GGCCCTTCAG TCTCTTGGCT ACACGGGTCT CTGCAGACTT GGCCCAGGCC
GCAAGGAACA GCTCCAGGCC AGAGCGTGAC ATGCATTCTT TACCAGACAT GGACCCTGGC
TCCTCCAGTT CTCTGGATCC CTCACTGGCT GGCTGTGGTG GTGATGGGAG CAGCGGCTCA
GGGGATGCCC ACTCTTGGGA CACCCTGCTC AGGAAATGGG AGCCAGTGCT GCGGGACTGC
CTGCTGAGAA ACCGGAGGCA GATGGAGGTA ATATCCTTAA GATTAAAACT TCAGAAACTT
CAGGAAGATG CAGTTGAGAA TGATGATTAT GATAAAGCTG AGACGTTACA ACAAAGATTA
GAAGACCTGG AACAAGAGAA AATCAGCCTG CACTTTCAAC TTCCTTCAAG GCAGCCAGCT
CTTAGCAGTT TCCTGGGTCA CCTGGCAGCA CAAGTCCAGG CTGCCTTGCG CCGTGGGGCC
ACTCAGCAGG CCAGCGGAGA TGACACCCAC ACCCCACTGA GAATGGAGCC GAGGCTGTTG
GAACCCACTG CTCAGGACAG CTTGCACGTG TCCATCACGA GACGAGACTG GCTTCTTCAG
GAAAAGCAGC AGCTACAGAA AGAAATCGAA GCTCTCCAAG CAAGGATGTT TGTGCTGGAA
GCCAAAGATC AACAGCTGAG AAGGGAAATA GAGGAGCAAG AGCAGCAACT CCAGTGGCAG
GGCTGCGACC TGACCCCACT GGTGGGCCAG CTGTCCCTGG GTCAGCTGCA GGAGGTCAGC
AAGGCCTTGC AGGACACCCT GGCCTCAGCC GGTCAGATTC CCTTCCATGC AGAGCCACCG
GAAACCATAA GGAGCCTCCA GGAAAGAATA AAATCCCTCA ACTTGTCACT TAAAGAAATC
ACTACTAAGG TGTGTATGAG TGAGAAATTC TGCAGCACCC TGAGGAAGAA AGTTAACGAT
ATTGAAACCC AACTACCAGC CTTGCTTGAA GCCAAAATGC ATGCCATATC AGGAAACCAT
TTCTGGACGG CTAAAGACCT CACCGAGGAG ATTAGATCAT TAACATCAGA GAGAGAAGGG
CTGGAGGGAC TCCTCAGCAA GCTGTTGGTG TTGAGTTCCA GGAATGTCAA AAAGCTGGGA
AGTGTTAAAG AAGATTACAA CAGACTGAGA AGAGAAGTGG AGCACCAGGA GACTGCCTAT
GGATATAAGT ACTGTGATGC AGAGTCCTGG ACACAGAGAA GTCAGCAACT TGCCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001012977.1
CDS54..2090
Misc Feature(1)54..929(+)
Misc Feature(2)1062..2030(+)
Misc Feature(3)1371..1844(+)
Exon (1)1..120
Gene:DISC1
Gene Synonym:
Exon (2)121..1100
Gene:DISC1
Gene Synonym:
Exon (3)1101..1170
Gene:DISC1
Gene Synonym:
Exon (4)1171..1321
Gene:DISC1
Gene Synonym:
Exon (5)1322..1451
Gene:DISC1
Gene Synonym:
Exon (6)1452..1687
Gene:DISC1
Gene Synonym:
Exon (7)1688..1742
Gene:DISC1
Gene Synonym:
Exon (8)1743..1845
Gene:DISC1
Gene Synonym:
Exon (9)1846..2034
Gene:DISC1
Gene Synonym:
Exon (10)2035..2220
Gene:DISC1
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001012959
Organism Homo sapiens (human)
Definition Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant S, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001012959

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
ATGCCAGGCG GGGGTCCTCA GGGCGCCCCA GCCGCCGCCG GCGGCGGCGG CGTGAGCCAC 
CGCGCAGGCA GCCGGGATTG CTTACCACCT GCAGCGTGCT TTCGGAGGCG GCGGCTGGCA
CGGAGGCCGG GCTACATGAG AAGCTCGACA GGGCCTGGGA TCGGGTTCCT TTCCCCAGCA
GTGGGCACAC TGTTCCGGTT CCCAGGAGGG GTGTCTGGCG AGGAGTCCCA CCACTCGGAG
TCCAGGGCCA GACAGTGTGG CCTTGACTCG AGAGGCCTCT TGGTCCGGAG CCCTGTTTCC
AAGAGTGCAG CAGCCCCTAC TGTGACCTCT GTGAGAGGAA CCTCGGCGCA CTTTGGGATT
CAGCTCAGAG GTGGCACCAG ATTGCCTGAC AGGCTTAGCT GGCCGTGTGG CCCTGGGAGT
GCTGGGTGGC AGCAAGAGTT TGCAGCCATG GATAGTTCTG AGACCCTGGA CGCCAGCTGG
GAGGCAGCCT GCAGCGATGG AGCAAGGCGT GTCCGGGCAG CAGGCTCTCT GCCATCAGCA
GAGTTGAGTA GCAACAGCTG CAGCCCTGGC TGTGGCCCTG AGGTCCCCCC AACCCCTCCT
GGCTCTCACA GTGCCTTTAC CTCAAGCTTT AGCTTTATTC GGCTCTCGCT TGGCTCTGCC
GGGGAACGTG GAGAAGCAGA AGGCTGCCCA CCATCCAGAG AGGCTGAGTC CCATTGCCAG
AGCCCCCAGG AGATGGGAGC CAAAGCTGCC AGCTTGGACG GGCCTCACGA GGACCCGCGA
TGTCTCTCTC GGCCCTTCAG TCTCTTGGCT ACACGGGTCT CTGCAGACTT GGCCCAGGCC
GCAAGGAACA GCTCCAGGCC AGAGCGTGAC ATGCATTCTT TACCAGACAT GGACCCTGGC
TCCTCCAGTT CTCTGGATCC CTCACTGGCT GGCTGTGGTG GTGATGGGAG CAGCGGCTCA
GGGGATGCCC ACTCTTGGGA CACCCTGCTC AGGAAATGGG AGCCAGTGCT GCGGGACTGC
CTGCTGAGAA ACCGGAGGCA GATGGAGGTA ATATCCTTAA GATTAAAACT TCAGAAACTT
CAGGAAGATG CAGTTGAGAA TGATGATTAT GATAAAGCTG AGACGTTACA ACAAAGATTA
GAAGACCTGG AACAAGAGAA AATCAGCCTG CACTTTCAAC TTCCTTCAAG GCAGCCAGCT
CTTAGCAGTT TCCTGGGTCA CCTGGCAGCA CAAGTCCAGG CTGCCTTGCG CCGTGGGGCC
ACTCAGCAGG CCAGCGGAGA TGACACCCAC ACCCCACTGA GAATGGAGCC GAGGCTGTTG
GAACCCACTG CTCAGGACAG CTTGCACGTG TCCATCACGA GACGAGACTG GCTTCTTCAG
GAAAAGCAGC AGCTACAGAA AGAAATCGAA GCTCTCCAAG CAAGGATGTT TGTGCTGGAA
GCCAAAGATC AACAGCTGAG AAGGGAAATA GAGGAGCAAG AGCAGCAACT CCAGTGGCAG
GGCTGCGACC TGACCCCACT GGTGGGCCAG CTGTCCCTGG GTCAGCTGCA GGAGGTCAGC
AAGGCCTTGC AGGACACCCT GGCCTCAGCC GGTCAGATTC CCTTCCATGC AGAGCCACCG
GAAACCATAA GGAGCCTCCA GGAAAGAATA AAATCCCTCA ACTTGTCACT TAAAGAAATC
ACTACTAAGG TGTGTATGAG TGAGAAATTC TGCAGCACCC TGAGGAAGAA AGTTAACGAT
ATTGAAACCC AACTACCAGC CTTGCTTGAA GCCAAAATGC ATGCCATATC AGGAAACCAT
TTCTGGACGG CTAAAGACCT CACCGAGGAG ATTAGATCAT TAACATCAGA GAGAGAAGGG
CTGGAGGGAC TCCTCAGCAA GCTGTTGGTG TTGAGTTCCA GGAATGTCAA AAAGCTGGGA
AGTGTTAAAG AAGATTACAA CAGACTGAGA AGAGAAGTGG AGCACCAGGA GACTGCCTAT
GGATATAAGT ACTGTGATGC AGAGTCCTGG ACACAGAGAA GTCAGCAACT TGCCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu25088
Clone ID Related Accession (Same CDS sequence) NM_001164537
Accession Version NM_001164537.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2661bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product disrupted in schizophrenia 1 protein isoform a
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from FJ804179.1 and AL450284.6. Transcript Variant: This variant (a) has an additional exon in the 5' coding region, as compared to variant L. The reading frame is not changed, but the resulting isoform (a, also known as isoform 8) is longer than isoform L. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: FJ804179.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1968540, SAMEA2142348 [ECO:0000350] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
ATGCCAGGCG GGGGTCCTCA GGGCGCCCCA GCCGCCGCCG GCGGCGGCGG CGTGAGCCAC 
CGCGCAGGCA GCCGGGATTG CTTACCACCT GCAGCGTGCT TTCGGAGGCG GCGGCTGGCA
CGGAGGCCGG GCTACATGAG AAGCTCGACA GGGCCTGGGA TCGGGTTCCT TTCCCCAGCA
GTGGGCACAC TGTTCCGGTT CCCAGGAGGG GTGTCTGGCG AGGAGTCCCA CCACTCGGAG
TCCAGGGCCA GACAGTGTGG CCTTGACTCG AGAGGCCTCT TGGTCCGGAG CCCTGTTTCC
AAGAGTGCAG CAGCCCCTAC TGTGACCTCT GTGAGAGGAA CCTCGGCGCA CTTTGGGATT
CAGCTCAGAG GTGGCACCAG ATTGCCTGAC AGGCTTAGCT GGCCGTGTGG CCCTGGGAGT
GCTGGGTGGC AGCAAGAGTT TGCAGCCATG GATAGTTCTG AGACCCTGGA CGCCAGCTGG
GAGGCAGCCT GCAGCGATGG AGCAAGGCGT GTCCGGGCAG CAGGCTCTCT GCCATCAGCA
GAGTTGAGTA GCAACAGCTG CAGCCCTGGC TGTGGCCCTG AGGTCCCCCC AACCCCTCCT
GGCTCTCACA GTGCCTTTAC CTCAAGCTTT AGCTTTATTC GGCTCTCGCT TGGCTCTGCC
GGGGAACGTG GAGAAGCAGA AGGCTGCCCA CCATCCAGAG AGGCTGAGTC CCATTGCCAG
AGCCCCCAGG AGATGGGAGC CAAAGCTGCC AGCTTGGACG GGCCTCACGA GGACCCGCGA
TGTCTCTCTC GGCCCTTCAG TCTCTTGGCT ACACGGGTCT CTGCAGACTT GGCCCAGGCC
GCAAGGAACA GCTCCAGGCC AGAGCGTGAC ATGCATTCTT TACCAGACAT GGACCCTGGC
TCCTCCAGTT CTCTGGATCC CTCACTGGCT GGCTGTGGTG GTGATGGGAG CAGCGGCTCA
GGGGATGCCC ACTCTTGGGA CACCCTGCTC AGGAAATGGG AGCCAGTGCT GCGGGACTGC
CTGCTGAGAA ACCGGAGGCA GATGGAGGTA ATATCCTTAA GATTAAAACT TCAGAAACTT
CAGGAAGATG CAGTTGAGAA TGATGATTAT GATAAAGTAG AGACGGGGTT TCACTATGTT
GGTCAAGCTG GTCTTGAACT CCTGACCTCA AGCAATCCAC CTGCTTCGGC CTCCCAAAGT
GCTGGGATTA CAGCTGAGAC GTTACAACAA AGATTAGAAG ACCTGGAACA AGAGAAAATC
AGCCTGCACT TTCAACTTCC TTCAAGGCAG CCAGCTCTTA GCAGTTTCCT GGGTCACCTG
GCAGCACAAG TCCAGGCTGC CTTGCGCCGT GGGGCCACTC AGCAGGCCAG CGGAGATGAC
ACCCACACCC CACTGAGAAT GGAGCCGAGG CTGTTGGAAC CCACTGCTCA GGACAGCTTG
CACGTGTCCA TCACGAGACG AGACTGGCTT CTTCAGGAAA AGCAGCAGCT ACAGAAAGAA
ATCGAAGCTC TCCAAGCAAG GATGTTTGTG CTGGAAGCCA AAGATCAACA GCTGAGAAGG
GAAATAGAGG AGCAAGAGCA GCAACTCCAG TGGCAGGGCT GCGACCTGAC CCCACTGGTG
GGCCAGCTGT CCCTGGGTCA GCTGCAGGAG GTCAGCAAGG CCTTGCAGGA CACCCTGGCC
TCAGCCGGTC AGATTCCCTT CCATGCAGAG CCACCGGAAA CCATAAGGAG CCTCCAGGAA
AGAATAAAAT CCCTCAACTT GTCACTTAAA GAAATCACTA CTAAGGTGTG TATGAGTGAG
AAATTCTGCA GCACCCTGAG GAAGAAAGTT AACGATATTG AAACCCAACT ACCAGCCTTG
CTTGAAGCCA AAATGCATGC CATATCAGGA AACCATTTCT GGACGGCTAA AGACCTCACC
GAGGAGATTA GATCATTAAC ATCAGAGAGA GAAGGGCTGG AGGGACTCCT CAGCAAGCTG
TTGGTGTTGA GTTCCAGGAA TGTCAAAAAG CTGGGAAGTG TTAAAGAAGA TTACAACAGA
CTGAGAAGAG AAGTGGAGCA CCAGGAGACT GCCTATGAAA CAAGTGTGAA GGAAAATACT
ATGAAGTACA TGGAAACACT TAAGAATAAA CTGTGCAGCT GCAAGTGTCC ACTGCTTGGG
AAAGTGTGGG AAGCTGACTT GGAAGCTTGT CGATTGCTTA TCCAGAGCCT ACAGCTCCAG
GAAGCCAGGG GAAGCCTGTC TGTAGAAGAT GAGAGGCAGA TGGATGACTT AGAGGGAGCT
GCTCCTCCTA TTCCCCCCAG GCTCCACTCC GAGGATAAAA GGAAGACCCC TTTGAAGGTA
TTGGAAGAAT GGAAGACTCA CCTCATCCCC TCTCTGCACT GTGCTGGAGG TGAACAGAAA
GAGGAATCTT ACATCCTTTC TGCAGAACTT GGAGAAAAGT GTGAAGACAT AGGCAAGAAG
CTATTGTACT TGGAAGATCA ACTTCACACA GCAATCCACA GTCATGATGA AGATCTCATT
CAGTCTCTCA GGAGGGAGCT CCAGATGGTG AAGGAAACTC TGCAGGCCAT GATCCTGCAG
CTCCAGCCAG CAAAGGAGGC GGGAGAAAGA GAAGCTGCAG CTTCCTGCAT GACAGCTGGT
GTCCACGAAG CACAAGCCTG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001158009.1
CDS54..2714
Misc Feature(1)1914..>2282(+)
Exon (1)1..120
Gene:DISC1
Gene Synonym:
Exon (2)121..1100
Gene:DISC1
Gene Synonym:
Exon (3)1101..1170
Gene:DISC1
Gene Synonym:
Exon (4)1171..1266
Gene:DISC1
Gene Synonym:
Exon (5)1267..1417
Gene:DISC1
Gene Synonym:
Exon (6)1418..1547
Gene:DISC1
Gene Synonym:
Exon (7)1548..1783
Gene:DISC1
Gene Synonym:
Exon (8)1784..1838
Gene:DISC1
Gene Synonym:
Exon (9)1839..1941
Gene:DISC1
Gene Synonym:
Exon (10)1942..2130
Gene:DISC1
Gene Synonym:
Exon (11)2131..2191
Gene:DISC1
Gene Synonym:
Exon (12)2192..2456
Gene:DISC1
Gene Synonym:
Exon (13)2457..2574
Gene:DISC1
Gene Synonym:
Exon (14)2575..7155
Gene:DISC1
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001164537
Organism Homo sapiens (human)
Definition Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant a, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001164537

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
ATGCCAGGCG GGGGTCCTCA GGGCGCCCCA GCCGCCGCCG GCGGCGGCGG CGTGAGCCAC 
CGCGCAGGCA GCCGGGATTG CTTACCACCT GCAGCGTGCT TTCGGAGGCG GCGGCTGGCA
CGGAGGCCGG GCTACATGAG AAGCTCGACA GGGCCTGGGA TCGGGTTCCT TTCCCCAGCA
GTGGGCACAC TGTTCCGGTT CCCAGGAGGG GTGTCTGGCG AGGAGTCCCA CCACTCGGAG
TCCAGGGCCA GACAGTGTGG CCTTGACTCG AGAGGCCTCT TGGTCCGGAG CCCTGTTTCC
AAGAGTGCAG CAGCCCCTAC TGTGACCTCT GTGAGAGGAA CCTCGGCGCA CTTTGGGATT
CAGCTCAGAG GTGGCACCAG ATTGCCTGAC AGGCTTAGCT GGCCGTGTGG CCCTGGGAGT
GCTGGGTGGC AGCAAGAGTT TGCAGCCATG GATAGTTCTG AGACCCTGGA CGCCAGCTGG
GAGGCAGCCT GCAGCGATGG AGCAAGGCGT GTCCGGGCAG CAGGCTCTCT GCCATCAGCA
GAGTTGAGTA GCAACAGCTG CAGCCCTGGC TGTGGCCCTG AGGTCCCCCC AACCCCTCCT
GGCTCTCACA GTGCCTTTAC CTCAAGCTTT AGCTTTATTC GGCTCTCGCT TGGCTCTGCC
GGGGAACGTG GAGAAGCAGA AGGCTGCCCA CCATCCAGAG AGGCTGAGTC CCATTGCCAG
AGCCCCCAGG AGATGGGAGC CAAAGCTGCC AGCTTGGACG GGCCTCACGA GGACCCGCGA
TGTCTCTCTC GGCCCTTCAG TCTCTTGGCT ACACGGGTCT CTGCAGACTT GGCCCAGGCC
GCAAGGAACA GCTCCAGGCC AGAGCGTGAC ATGCATTCTT TACCAGACAT GGACCCTGGC
TCCTCCAGTT CTCTGGATCC CTCACTGGCT GGCTGTGGTG GTGATGGGAG CAGCGGCTCA
GGGGATGCCC ACTCTTGGGA CACCCTGCTC AGGAAATGGG AGCCAGTGCT GCGGGACTGC
CTGCTGAGAA ACCGGAGGCA GATGGAGGTA ATATCCTTAA GATTAAAACT TCAGAAACTT
CAGGAAGATG CAGTTGAGAA TGATGATTAT GATAAAGTAG AGACGGGGTT TCACTATGTT
GGTCAAGCTG GTCTTGAACT CCTGACCTCA AGCAATCCAC CTGCTTCGGC CTCCCAAAGT
GCTGGGATTA CAGCTGAGAC GTTACAACAA AGATTAGAAG ACCTGGAACA AGAGAAAATC
AGCCTGCACT TTCAACTTCC TTCAAGGCAG CCAGCTCTTA GCAGTTTCCT GGGTCACCTG
GCAGCACAAG TCCAGGCTGC CTTGCGCCGT GGGGCCACTC AGCAGGCCAG CGGAGATGAC
ACCCACACCC CACTGAGAAT GGAGCCGAGG CTGTTGGAAC CCACTGCTCA GGACAGCTTG
CACGTGTCCA TCACGAGACG AGACTGGCTT CTTCAGGAAA AGCAGCAGCT ACAGAAAGAA
ATCGAAGCTC TCCAAGCAAG GATGTTTGTG CTGGAAGCCA AAGATCAACA GCTGAGAAGG
GAAATAGAGG AGCAAGAGCA GCAACTCCAG TGGCAGGGCT GCGACCTGAC CCCACTGGTG
GGCCAGCTGT CCCTGGGTCA GCTGCAGGAG GTCAGCAAGG CCTTGCAGGA CACCCTGGCC
TCAGCCGGTC AGATTCCCTT CCATGCAGAG CCACCGGAAA CCATAAGGAG CCTCCAGGAA
AGAATAAAAT CCCTCAACTT GTCACTTAAA GAAATCACTA CTAAGGTGTG TATGAGTGAG
AAATTCTGCA GCACCCTGAG GAAGAAAGTT AACGATATTG AAACCCAACT ACCAGCCTTG
CTTGAAGCCA AAATGCATGC CATATCAGGA AACCATTTCT GGACGGCTAA AGACCTCACC
GAGGAGATTA GATCATTAAC ATCAGAGAGA GAAGGGCTGG AGGGACTCCT CAGCAAGCTG
TTGGTGTTGA GTTCCAGGAA TGTCAAAAAG CTGGGAAGTG TTAAAGAAGA TTACAACAGA
CTGAGAAGAG AAGTGGAGCA CCAGGAGACT GCCTATGAAA CAAGTGTGAA GGAAAATACT
ATGAAGTACA TGGAAACACT TAAGAATAAA CTGTGCAGCT GCAAGTGTCC ACTGCTTGGG
AAAGTGTGGG AAGCTGACTT GGAAGCTTGT CGATTGCTTA TCCAGAGCCT ACAGCTCCAG
GAAGCCAGGG GAAGCCTGTC TGTAGAAGAT GAGAGGCAGA TGGATGACTT AGAGGGAGCT
GCTCCTCCTA TTCCCCCCAG GCTCCACTCC GAGGATAAAA GGAAGACCCC TTTGAAGGTA
TTGGAAGAAT GGAAGACTCA CCTCATCCCC TCTCTGCACT GTGCTGGAGG TGAACAGAAA
GAGGAATCTT ACATCCTTTC TGCAGAACTT GGAGAAAAGT GTGAAGACAT AGGCAAGAAG
CTATTGTACT TGGAAGATCA ACTTCACACA GCAATCCACA GTCATGATGA AGATCTCATT
CAGTCTCTCA GGAGGGAGCT CCAGATGGTG AAGGAAACTC TGCAGGCCAT GATCCTGCAG
CTCCAGCCAG CAAAGGAGGC GGGAGAAAGA GAAGCTGCAG CTTCCTGCAT GACAGCTGGT
GTCCACGAAG CACAAGCCTG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu24863
Clone ID Related Accession (Same CDS sequence) NM_001164538
Accession Version NM_001164538.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2412bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product disrupted in schizophrenia 1 protein isoform b
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from FJ804181.1 and BC142622.1. Transcript Variant: This variant (b) lacks two 3' exons but has an alternate 3' segment, as compared to variant L. The resulting isoform (b, also known as isoform 10) is shorter and has a distinct C-terminus, as compared to isoform L. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: FJ804181.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2142348 [ECO:0000348] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
ATGCCAGGCG GGGGTCCTCA GGGCGCCCCA GCCGCCGCCG GCGGCGGCGG CGTGAGCCAC 
CGCGCAGGCA GCCGGGATTG CTTACCACCT GCAGCGTGCT TTCGGAGGCG GCGGCTGGCA
CGGAGGCCGG GCTACATGAG AAGCTCGACA GGGCCTGGGA TCGGGTTCCT TTCCCCAGCA
GTGGGCACAC TGTTCCGGTT CCCAGGAGGG GTGTCTGGCG AGGAGTCCCA CCACTCGGAG
TCCAGGGCCA GACAGTGTGG CCTTGACTCG AGAGGCCTCT TGGTCCGGAG CCCTGTTTCC
AAGAGTGCAG CAGCCCCTAC TGTGACCTCT GTGAGAGGAA CCTCGGCGCA CTTTGGGATT
CAGCTCAGAG GTGGCACCAG ATTGCCTGAC AGGCTTAGCT GGCCGTGTGG CCCTGGGAGT
GCTGGGTGGC AGCAAGAGTT TGCAGCCATG GATAGTTCTG AGACCCTGGA CGCCAGCTGG
GAGGCAGCCT GCAGCGATGG AGCAAGGCGT GTCCGGGCAG CAGGCTCTCT GCCATCAGCA
GAGTTGAGTA GCAACAGCTG CAGCCCTGGC TGTGGCCCTG AGGTCCCCCC AACCCCTCCT
GGCTCTCACA GTGCCTTTAC CTCAAGCTTT AGCTTTATTC GGCTCTCGCT TGGCTCTGCC
GGGGAACGTG GAGAAGCAGA AGGCTGCCCA CCATCCAGAG AGGCTGAGTC CCATTGCCAG
AGCCCCCAGG AGATGGGAGC CAAAGCTGCC AGCTTGGACG GGCCTCACGA GGACCCGCGA
TGTCTCTCTC GGCCCTTCAG TCTCTTGGCT ACACGGGTCT CTGCAGACTT GGCCCAGGCC
GCAAGGAACA GCTCCAGGCC AGAGCGTGAC ATGCATTCTT TACCAGACAT GGACCCTGGC
TCCTCCAGTT CTCTGGATCC CTCACTGGCT GGCTGTGGTG GTGATGGGAG CAGCGGCTCA
GGGGATGCCC ACTCTTGGGA CACCCTGCTC AGGAAATGGG AGCCAGTGCT GCGGGACTGC
CTGCTGAGAA ACCGGAGGCA GATGGAGGTA ATATCCTTAA GATTAAAACT TCAGAAACTT
CAGGAAGATG CAGTTGAGAA TGATGATTAT GATAAAGCTG AGACGTTACA ACAAAGATTA
GAAGACCTGG AACAAGAGAA AATCAGCCTG CACTTTCAAC TTCCTTCAAG GCAGCCAGCT
CTTAGCAGTT TCCTGGGTCA CCTGGCAGCA CAAGTCCAGG CTGCCTTGCG CCGTGGGGCC
ACTCAGCAGG CCAGCGGAGA TGACACCCAC ACCCCACTGA GAATGGAGCC GAGGCTGTTG
GAACCCACTG CTCAGGACAG CTTGCACGTG TCCATCACGA GACGAGACTG GCTTCTTCAG
GAAAAGCAGC AGCTACAGAA AGAAATCGAA GCTCTCCAAG CAAGGATGTT TGTGCTGGAA
GCCAAAGATC AACAGCTGAG AAGGGAAATA GAGGAGCAAG AGCAGCAACT CCAGTGGCAG
GGCTGCGACC TGACCCCACT GGTGGGCCAG CTGTCCCTGG GTCAGCTGCA GGAGGTCAGC
AAGGCCTTGC AGGACACCCT GGCCTCAGCC GGTCAGATTC CCTTCCATGC AGAGCCACCG
GAAACCATAA GGAGCCTCCA GGAAAGAATA AAATCCCTCA ACTTGTCACT TAAAGAAATC
ACTACTAAGG TGTGTATGAG TGAGAAATTC TGCAGCACCC TGAGGAAGAA AGTTAACGAT
ATTGAAACCC AACTACCAGC CTTGCTTGAA GCCAAAATGC ATGCCATATC AGGAAACCAT
TTCTGGACGG CTAAAGACCT CACCGAGGAG ATTAGATCAT TAACATCAGA GAGAGAAGGG
CTGGAGGGAC TCCTCAGCAA GCTGTTGGTG TTGAGTTCCA GGAATGTCAA AAAGCTGGGA
AGTGTTAAAG AAGATTACAA CAGACTGAGA AGAGAAGTGG AGCACCAGGA GACTGCCTAT
GAAACAAGTG TGAAGGAAAA TACTATGAAG TACATGGAAA CACTTAAGAA TAAACTGTGC
AGCTGCAAGT GTCCACTGCT TGGGAAAGTG TGGGAAGCTG ACTTGGAAGC TTGTCGATTG
CTTATCCAGA GCCTACAGCT CCAGGAAGCC AGGGGAAGCC TGTCTGTAGA AGATGAGAGG
CAGATGGATG ACTTAGAGGG AGCTGCTCCT CCTATTCCCC CCAGGCTCCA CTCCGAGGAT
AAAAGGAAGA CCCCTTTGAA GGTATTGGAA GAATGGAAGA CTCACCTCAT CCCCTCTCTG
CACTGTGCTG GAGGTGAACA GAAAGAGGTC TGTCCTTTTC ACATGGCCTC CAGAGGGGAC
CCTTATTCTA AGGGGTGCTT TGGGACCATG CTCCAAATGG GAACAATAAA TATTGGGAAG
GCTTCCCATT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001158010.1
CDS54..2465
Misc Feature(1)54..929(+)
Misc Feature(2)930..2141(+)
Misc Feature(3)1371..1844(+)
Misc Feature(4)1818..>2186(+)
Exon (1)1..120
Gene:DISC1
Gene Synonym:
Exon (2)121..1100
Gene:DISC1
Gene Synonym:
Exon (3)1101..1170
Gene:DISC1
Gene Synonym:
Exon (4)1171..1321
Gene:DISC1
Gene Synonym:
Exon (5)1322..1451
Gene:DISC1
Gene Synonym:
Exon (6)1452..1687
Gene:DISC1
Gene Synonym:
Exon (7)1688..1742
Gene:DISC1
Gene Synonym:
Exon (8)1743..1845
Gene:DISC1
Gene Synonym:
Exon (9)1846..2034
Gene:DISC1
Gene Synonym:
Exon (10)2035..2095
Gene:DISC1
Gene Synonym:
Exon (11)2096..2965
Gene:DISC1
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001164538
Organism Homo sapiens (human)
Definition Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant b, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001164538

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
ATGCCAGGCG GGGGTCCTCA GGGCGCCCCA GCCGCCGCCG GCGGCGGCGG CGTGAGCCAC 
CGCGCAGGCA GCCGGGATTG CTTACCACCT GCAGCGTGCT TTCGGAGGCG GCGGCTGGCA
CGGAGGCCGG GCTACATGAG AAGCTCGACA GGGCCTGGGA TCGGGTTCCT TTCCCCAGCA
GTGGGCACAC TGTTCCGGTT CCCAGGAGGG GTGTCTGGCG AGGAGTCCCA CCACTCGGAG
TCCAGGGCCA GACAGTGTGG CCTTGACTCG AGAGGCCTCT TGGTCCGGAG CCCTGTTTCC
AAGAGTGCAG CAGCCCCTAC TGTGACCTCT GTGAGAGGAA CCTCGGCGCA CTTTGGGATT
CAGCTCAGAG GTGGCACCAG ATTGCCTGAC AGGCTTAGCT GGCCGTGTGG CCCTGGGAGT
GCTGGGTGGC AGCAAGAGTT TGCAGCCATG GATAGTTCTG AGACCCTGGA CGCCAGCTGG
GAGGCAGCCT GCAGCGATGG AGCAAGGCGT GTCCGGGCAG CAGGCTCTCT GCCATCAGCA
GAGTTGAGTA GCAACAGCTG CAGCCCTGGC TGTGGCCCTG AGGTCCCCCC AACCCCTCCT
GGCTCTCACA GTGCCTTTAC CTCAAGCTTT AGCTTTATTC GGCTCTCGCT TGGCTCTGCC
GGGGAACGTG GAGAAGCAGA AGGCTGCCCA CCATCCAGAG AGGCTGAGTC CCATTGCCAG
AGCCCCCAGG AGATGGGAGC CAAAGCTGCC AGCTTGGACG GGCCTCACGA GGACCCGCGA
TGTCTCTCTC GGCCCTTCAG TCTCTTGGCT ACACGGGTCT CTGCAGACTT GGCCCAGGCC
GCAAGGAACA GCTCCAGGCC AGAGCGTGAC ATGCATTCTT TACCAGACAT GGACCCTGGC
TCCTCCAGTT CTCTGGATCC CTCACTGGCT GGCTGTGGTG GTGATGGGAG CAGCGGCTCA
GGGGATGCCC ACTCTTGGGA CACCCTGCTC AGGAAATGGG AGCCAGTGCT GCGGGACTGC
CTGCTGAGAA ACCGGAGGCA GATGGAGGTA ATATCCTTAA GATTAAAACT TCAGAAACTT
CAGGAAGATG CAGTTGAGAA TGATGATTAT GATAAAGCTG AGACGTTACA ACAAAGATTA
GAAGACCTGG AACAAGAGAA AATCAGCCTG CACTTTCAAC TTCCTTCAAG GCAGCCAGCT
CTTAGCAGTT TCCTGGGTCA CCTGGCAGCA CAAGTCCAGG CTGCCTTGCG CCGTGGGGCC
ACTCAGCAGG CCAGCGGAGA TGACACCCAC ACCCCACTGA GAATGGAGCC GAGGCTGTTG
GAACCCACTG CTCAGGACAG CTTGCACGTG TCCATCACGA GACGAGACTG GCTTCTTCAG
GAAAAGCAGC AGCTACAGAA AGAAATCGAA GCTCTCCAAG CAAGGATGTT TGTGCTGGAA
GCCAAAGATC AACAGCTGAG AAGGGAAATA GAGGAGCAAG AGCAGCAACT CCAGTGGCAG
GGCTGCGACC TGACCCCACT GGTGGGCCAG CTGTCCCTGG GTCAGCTGCA GGAGGTCAGC
AAGGCCTTGC AGGACACCCT GGCCTCAGCC GGTCAGATTC CCTTCCATGC AGAGCCACCG
GAAACCATAA GGAGCCTCCA GGAAAGAATA AAATCCCTCA ACTTGTCACT TAAAGAAATC
ACTACTAAGG TGTGTATGAG TGAGAAATTC TGCAGCACCC TGAGGAAGAA AGTTAACGAT
ATTGAAACCC AACTACCAGC CTTGCTTGAA GCCAAAATGC ATGCCATATC AGGAAACCAT
TTCTGGACGG CTAAAGACCT CACCGAGGAG ATTAGATCAT TAACATCAGA GAGAGAAGGG
CTGGAGGGAC TCCTCAGCAA GCTGTTGGTG TTGAGTTCCA GGAATGTCAA AAAGCTGGGA
AGTGTTAAAG AAGATTACAA CAGACTGAGA AGAGAAGTGG AGCACCAGGA GACTGCCTAT
GAAACAAGTG TGAAGGAAAA TACTATGAAG TACATGGAAA CACTTAAGAA TAAACTGTGC
AGCTGCAAGT GTCCACTGCT TGGGAAAGTG TGGGAAGCTG ACTTGGAAGC TTGTCGATTG
CTTATCCAGA GCCTACAGCT CCAGGAAGCC AGGGGAAGCC TGTCTGTAGA AGATGAGAGG
CAGATGGATG ACTTAGAGGG AGCTGCTCCT CCTATTCCCC CCAGGCTCCA CTCCGAGGAT
AAAAGGAAGA CCCCTTTGAA GGTATTGGAA GAATGGAAGA CTCACCTCAT CCCCTCTCTG
CACTGTGCTG GAGGTGAACA GAAAGAGGTC TGTCCTTTTC ACATGGCCTC CAGAGGGGAC
CCTTATTCTA AGGGGTGCTT TGGGACCATG CTCCAAATGG GAACAATAAA TATTGGGAAG
GCTTCCCATT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu24938
Clone ID Related Accession (Same CDS sequence) NM_001164539
Accession Version NM_001164539.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2268bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product disrupted in schizophrenia 1 protein isoform c
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from FJ804196.1. Transcript Variant: This variant (c) lacks several 3' exons but has an alternate 3' exon, as compared to variant L. The resulting isoform (c, also known as isoform 26) is shorter and has a distinct C-terminus, as compared to isoform L. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: FJ804196.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1968540, SAMEA2142348 [ECO:0000350] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
ATGCCAGGCG GGGGTCCTCA GGGCGCCCCA GCCGCCGCCG GCGGCGGCGG CGTGAGCCAC 
CGCGCAGGCA GCCGGGATTG CTTACCACCT GCAGCGTGCT TTCGGAGGCG GCGGCTGGCA
CGGAGGCCGG GCTACATGAG AAGCTCGACA GGGCCTGGGA TCGGGTTCCT TTCCCCAGCA
GTGGGCACAC TGTTCCGGTT CCCAGGAGGG GTGTCTGGCG AGGAGTCCCA CCACTCGGAG
TCCAGGGCCA GACAGTGTGG CCTTGACTCG AGAGGCCTCT TGGTCCGGAG CCCTGTTTCC
AAGAGTGCAG CAGCCCCTAC TGTGACCTCT GTGAGAGGAA CCTCGGCGCA CTTTGGGATT
CAGCTCAGAG GTGGCACCAG ATTGCCTGAC AGGCTTAGCT GGCCGTGTGG CCCTGGGAGT
GCTGGGTGGC AGCAAGAGTT TGCAGCCATG GATAGTTCTG AGACCCTGGA CGCCAGCTGG
GAGGCAGCCT GCAGCGATGG AGCAAGGCGT GTCCGGGCAG CAGGCTCTCT GCCATCAGCA
GAGTTGAGTA GCAACAGCTG CAGCCCTGGC TGTGGCCCTG AGGTCCCCCC AACCCCTCCT
GGCTCTCACA GTGCCTTTAC CTCAAGCTTT AGCTTTATTC GGCTCTCGCT TGGCTCTGCC
GGGGAACGTG GAGAAGCAGA AGGCTGCCCA CCATCCAGAG AGGCTGAGTC CCATTGCCAG
AGCCCCCAGG AGATGGGAGC CAAAGCTGCC AGCTTGGACG GGCCTCACGA GGACCCGCGA
TGTCTCTCTC GGCCCTTCAG TCTCTTGGCT ACACGGGTCT CTGCAGACTT GGCCCAGGCC
GCAAGGAACA GCTCCAGGCC AGAGCGTGAC ATGCATTCTT TACCAGACAT GGACCCTGGC
TCCTCCAGTT CTCTGGATCC CTCACTGGCT GGCTGTGGTG GTGATGGGAG CAGCGGCTCA
GGGGATGCCC ACTCTTGGGA CACCCTGCTC AGGAAATGGG AGCCAGTGCT GCGGGACTGC
CTGCTGAGAA ACCGGAGGCA GATGGAGGTA ATATCCTTAA GATTAAAACT TCAGAAACTT
CAGGAAGATG CAGTTGAGAA TGATGATTAT GATAAAGCTG AGACGTTACA ACAAAGATTA
GAAGACCTGG AACAAGAGAA AATCAGCCTG CACTTTCAAC TTCCTTCAAG GCAGCCAGCT
CTTAGCAGTT TCCTGGGTCA CCTGGCAGCA CAAGTCCAGG CTGCCTTGCG CCGTGGGGCC
ACTCAGCAGG CCAGCGGAGA TGACACCCAC ACCCCACTGA GAATGGAGCC GAGGCTGTTG
GAACCCACTG CTCAGGACAG CTTGCACGTG TCCATCACGA GACGAGACTG GCTTCTTCAG
GAAAAGCAGC AGCTACAGAA AGAAATCGAA GCTCTCCAAG CAAGGATGTT TGTGCTGGAA
GCCAAAGATC AACAGCTGAG AAGGGAAATA GAGGAGCAAG AGCAGCAACT CCAGTGGCAG
GGCTGCGACC TGACCCCACT GGTGGGCCAG CTGTCCCTGG GTCAGCTGCA GGAGGTCAGC
AAGGCCTTGC AGGACACCCT GGCCTCAGCC GGTCAGATTC CCTTCCATGC AGAGCCACCG
GAAACCATAA GGAGCCTCCA GGAAAGAATA AAATCCCTCA ACTTGTCACT TAAAGAAATC
ACTACTAAGG TGTGTATGAG TGAGAAATTC TGCAGCACCC TGAGGAAGAA AGTTAACGAT
ATTGAAACCC AACTACCAGC CTTGCTTGAA GCCAAAATGC ATGCCATATC AGGAAACCAT
TTCTGGACGG CTAAAGACCT CACCGAGGAG ATTAGATCAT TAACATCAGA GAGAGAAGGG
CTGGAGGGAC TCCTCAGCAA GCTGTTGGTG TTGAGTTCCA GGAATGTCAA AAAGCTGGGA
AGTGTTAAAG AAGATTACAA CAGACTGAGA AGAGAAGTGG AGCACCAGGA GACTGCCTAT
GATGGAGTCT CACTCTGTCG CCCAGTCTGG AGTGCAGTGG TACGATCTTG CTCACTGCAA
CCTCTGCCTC CCGAGTTCAA GCAATTCTCC TGCCTCAGCC TCCGGAGTAG CTGGGATTAC
AGGTGCCCGC CACCATGCCT GGCTAATTTT GTATTCTTAG TAGAGATGGG GTTTTACCAT
GTTGACCAGA CTGGTCTAAA ACTCCTGACC TCAAGTGATC CACCTTCCTC AGCCTCCCAA
AGTGCTGGGA TTACAGACAT GAGCCACTGT GCCTGGCCCC TACAATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001158011.1
CDS54..2321
Misc Feature(1)54..929(+)
Misc Feature(2)1371..1844(+)
Misc Feature(3)2082..2192(+)
Exon (1)1..120
Gene:DISC1
Gene Synonym:
Exon (2)121..1100
Gene:DISC1
Gene Synonym:
Exon (3)1101..1170
Gene:DISC1
Gene Synonym:
Exon (4)1171..1321
Gene:DISC1
Gene Synonym:
Exon (5)1322..1451
Gene:DISC1
Gene Synonym:
Exon (6)1452..1687
Gene:DISC1
Gene Synonym:
Exon (7)1688..1742
Gene:DISC1
Gene Synonym:
Exon (8)1743..1845
Gene:DISC1
Gene Synonym:
Exon (9)1846..2034
Gene:DISC1
Gene Synonym:
Exon (10)2035..2676
Gene:DISC1
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001164539
Organism Homo sapiens (human)
Definition Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant c, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001164539

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
ATGCCAGGCG GGGGTCCTCA GGGCGCCCCA GCCGCCGCCG GCGGCGGCGG CGTGAGCCAC 
CGCGCAGGCA GCCGGGATTG CTTACCACCT GCAGCGTGCT TTCGGAGGCG GCGGCTGGCA
CGGAGGCCGG GCTACATGAG AAGCTCGACA GGGCCTGGGA TCGGGTTCCT TTCCCCAGCA
GTGGGCACAC TGTTCCGGTT CCCAGGAGGG GTGTCTGGCG AGGAGTCCCA CCACTCGGAG
TCCAGGGCCA GACAGTGTGG CCTTGACTCG AGAGGCCTCT TGGTCCGGAG CCCTGTTTCC
AAGAGTGCAG CAGCCCCTAC TGTGACCTCT GTGAGAGGAA CCTCGGCGCA CTTTGGGATT
CAGCTCAGAG GTGGCACCAG ATTGCCTGAC AGGCTTAGCT GGCCGTGTGG CCCTGGGAGT
GCTGGGTGGC AGCAAGAGTT TGCAGCCATG GATAGTTCTG AGACCCTGGA CGCCAGCTGG
GAGGCAGCCT GCAGCGATGG AGCAAGGCGT GTCCGGGCAG CAGGCTCTCT GCCATCAGCA
GAGTTGAGTA GCAACAGCTG CAGCCCTGGC TGTGGCCCTG AGGTCCCCCC AACCCCTCCT
GGCTCTCACA GTGCCTTTAC CTCAAGCTTT AGCTTTATTC GGCTCTCGCT TGGCTCTGCC
GGGGAACGTG GAGAAGCAGA AGGCTGCCCA CCATCCAGAG AGGCTGAGTC CCATTGCCAG
AGCCCCCAGG AGATGGGAGC CAAAGCTGCC AGCTTGGACG GGCCTCACGA GGACCCGCGA
TGTCTCTCTC GGCCCTTCAG TCTCTTGGCT ACACGGGTCT CTGCAGACTT GGCCCAGGCC
GCAAGGAACA GCTCCAGGCC AGAGCGTGAC ATGCATTCTT TACCAGACAT GGACCCTGGC
TCCTCCAGTT CTCTGGATCC CTCACTGGCT GGCTGTGGTG GTGATGGGAG CAGCGGCTCA
GGGGATGCCC ACTCTTGGGA CACCCTGCTC AGGAAATGGG AGCCAGTGCT GCGGGACTGC
CTGCTGAGAA ACCGGAGGCA GATGGAGGTA ATATCCTTAA GATTAAAACT TCAGAAACTT
CAGGAAGATG CAGTTGAGAA TGATGATTAT GATAAAGCTG AGACGTTACA ACAAAGATTA
GAAGACCTGG AACAAGAGAA AATCAGCCTG CACTTTCAAC TTCCTTCAAG GCAGCCAGCT
CTTAGCAGTT TCCTGGGTCA CCTGGCAGCA CAAGTCCAGG CTGCCTTGCG CCGTGGGGCC
ACTCAGCAGG CCAGCGGAGA TGACACCCAC ACCCCACTGA GAATGGAGCC GAGGCTGTTG
GAACCCACTG CTCAGGACAG CTTGCACGTG TCCATCACGA GACGAGACTG GCTTCTTCAG
GAAAAGCAGC AGCTACAGAA AGAAATCGAA GCTCTCCAAG CAAGGATGTT TGTGCTGGAA
GCCAAAGATC AACAGCTGAG AAGGGAAATA GAGGAGCAAG AGCAGCAACT CCAGTGGCAG
GGCTGCGACC TGACCCCACT GGTGGGCCAG CTGTCCCTGG GTCAGCTGCA GGAGGTCAGC
AAGGCCTTGC AGGACACCCT GGCCTCAGCC GGTCAGATTC CCTTCCATGC AGAGCCACCG
GAAACCATAA GGAGCCTCCA GGAAAGAATA AAATCCCTCA ACTTGTCACT TAAAGAAATC
ACTACTAAGG TGTGTATGAG TGAGAAATTC TGCAGCACCC TGAGGAAGAA AGTTAACGAT
ATTGAAACCC AACTACCAGC CTTGCTTGAA GCCAAAATGC ATGCCATATC AGGAAACCAT
TTCTGGACGG CTAAAGACCT CACCGAGGAG ATTAGATCAT TAACATCAGA GAGAGAAGGG
CTGGAGGGAC TCCTCAGCAA GCTGTTGGTG TTGAGTTCCA GGAATGTCAA AAAGCTGGGA
AGTGTTAAAG AAGATTACAA CAGACTGAGA AGAGAAGTGG AGCACCAGGA GACTGCCTAT
GATGGAGTCT CACTCTGTCG CCCAGTCTGG AGTGCAGTGG TACGATCTTG CTCACTGCAA
CCTCTGCCTC CCGAGTTCAA GCAATTCTCC TGCCTCAGCC TCCGGAGTAG CTGGGATTAC
AGGTGCCCGC CACCATGCCT GGCTAATTTT GTATTCTTAG TAGAGATGGG GTTTTACCAT
GTTGACCAGA CTGGTCTAAA ACTCCTGACC TCAAGTGATC CACCTTCCTC AGCCTCCCAA
AGTGCTGGGA TTACAGACAT GAGCCACTGT GCCTGGCCCC TACAATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu24750
Clone ID Related Accession (Same CDS sequence) NM_001164540
Accession Version NM_001164540.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2199bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product disrupted in schizophrenia 1 protein isoform d
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from FJ804177.1. Transcript Variant: This variant (d) lacks two internal exons in the 5' region, as compared to variant L. The reading frame is not changed, and the resulting isoform (d, also kown as isoform 6) lacks an internal segment, as compared to isoform L. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: FJ804177.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1968540, SAMEA2142348 [ECO:0000350] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
ATGCCAGGCG GGGGTCCTCA GGGCGCCCCA GCCGCCGCCG GCGGCGGCGG CGTGAGCCAC 
CGCGCAGGCA GCCGGGATTG CTTACCACCT GCAGCGTGCT TTCGGAGGCG GCGGCTGGCA
CGGAGGCCGG GCTACATGAG AAGCTCGACA GGGCCTGGGA TCGGGTTCCT TTCCCCAGCA
GTGGGCACAC TGTTCCGGTT CCCAGGAGGG GTGTCTGGCG AGGAGTCCCA CCACTCGGAG
TCCAGGGCCA GACAGTGTGG CCTTGACTCG AGAGGCCTCT TGGTCCGGAG CCCTGTTTCC
AAGAGTGCAG CAGCCCCTAC TGTGACCTCT GTGAGAGGAA CCTCGGCGCA CTTTGGGATT
CAGCTCAGAG GTGGCACCAG ATTGCCTGAC AGGCTTAGCT GGCCGTGTGG CCCTGGGAGT
GCTGGGTGGC AGCAAGAGTT TGCAGCCATG GATAGTTCTG AGACCCTGGA CGCCAGCTGG
GAGGCAGCCT GCAGCGATGG AGCAAGGCGT GTCCGGGCAG CAGGCTCTCT GCCATCAGCA
GAGTTGAGTA GCAACAGCTG CAGCCCTGGC TGTGGCCCTG AGGTCCCCCC AACCCCTCCT
GGCTCTCACA GTGCCTTTAC CTCAAGCTTT AGCTTTATTC GGCTCTCGCT TGGCTCTGCC
GGGGAACGTG GAGAAGCAGA AGGCTGCCCA CCATCCAGAG AGGCTGAGTC CCATTGCCAG
AGCCCCCAGG AGATGGGAGC CAAAGCTGCC AGCTTGGACG GGCCTCACGA GGACCCGCGA
TGTCTCTCTC GGCCCTTCAG TCTCTTGGCT ACACGGGTCT CTGCAGACTT GGCCCAGGCC
GCAAGGAACA GCTCCAGGCC AGAGCGTGAC ATGCATTCTT TACCAGACAT GGACCCTGGC
TCCTCCAGTT CTCTGGATCC CTCACTGGCT GGCTGTGGTG GTGATGGGAG CAGCGGCTCA
GGGGATGCCC ACTCTTGGGA CACCCTGCTC AGGAAATGGG AGCCAGTGCT GCGGGACTGC
CTGCTGAGAA ACCGGAGGCA GATGGAGGTA ATATCCTTAA GATTAAAACT TCAGAAACTT
CAGGAAGATG CAGTTGAGAA TGATGATTAT GATAAAGCTG AGACGTTACA ACAAAGATTA
GAAGACCTGG AACAAGAGAA AATCAGCCTG CACTTTCAAC TTCCTTCAAG GCAGCCAGCT
CTTAGCAGTT TCCTGGGTCA CCTGGCAGCA CAAGTCCAGG CTGCCTTGCG CCGTGGGGCC
ACTCAGCACC TCCAGGAAAG AATAAAATCC CTCAACTTGT CACTTAAAGA AATCACTACT
AAGGTGTGTA TGAGTGAGAA ATTCTGCAGC ACCCTGAGGA AGAAAGTTAA CGATATTGAA
ACCCAACTAC CAGCCTTGCT TGAAGCCAAA ATGCATGCCA TATCAGGAAA CCATTTCTGG
ACGGCTAAAG ACCTCACCGA GGAGATTAGA TCATTAACAT CAGAGAGAGA AGGGCTGGAG
GGACTCCTCA GCAAGCTGTT GGTGTTGAGT TCCAGGAATG TCAAAAAGCT GGGAAGTGTT
AAAGAAGATT ACAACAGACT GAGAAGAGAA GTGGAGCACC AGGAGACTGC CTATGAAACA
AGTGTGAAGG AAAATACTAT GAAGTACATG GAAACACTTA AGAATAAACT GTGCAGCTGC
AAGTGTCCAC TGCTTGGGAA AGTGTGGGAA GCTGACTTGG AAGCTTGTCG ATTGCTTATC
CAGAGCCTAC AGCTCCAGGA AGCCAGGGGA AGCCTGTCTG TAGAAGATGA GAGGCAGATG
GATGACTTAG AGGGAGCTGC TCCTCCTATT CCCCCCAGGC TCCACTCCGA GGATAAAAGG
AAGACCCCTT TGAAGGTATT GGAAGAATGG AAGACTCACC TCATCCCCTC TCTGCACTGT
GCTGGAGGTG AACAGAAAGA GGAATCTTAC ATCCTTTCTG CAGAACTTGG AGAAAAGTGT
GAAGACATAG GCAAGAAGCT ATTGTACTTG GAAGATCAAC TTCACACAGC AATCCACAGT
CATGATGAAG ATCTCATTCA GTCTCTCAGG AGGGAGCTCC AGATGGTGAA GGAAACTCTG
CAGGCCATGA TCCTGCAGCT CCAGCCAGCA AAGGAGGCGG GAGAAAGAGA AGCTGCAGCT
TCCTGCATGA CAGCTGGTGT CCACGAAGCA CAAGCCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001158012.1
CDS54..2252
Misc Feature(1)54..929(+)
Misc Feature(2)1452..>1820(+)
Exon (1)1..120
Gene:DISC1
Gene Synonym:
Exon (2)121..1100
Gene:DISC1
Gene Synonym:
Exon (3)1101..1170
Gene:DISC1
Gene Synonym:
Exon (4)1171..1321
Gene:DISC1
Gene Synonym:
Exon (5)1322..1376
Gene:DISC1
Gene Synonym:
Exon (6)1377..1479
Gene:DISC1
Gene Synonym:
Exon (7)1480..1668
Gene:DISC1
Gene Synonym:
Exon (8)1669..1729
Gene:DISC1
Gene Synonym:
Exon (9)1730..1994
Gene:DISC1
Gene Synonym:
Exon (10)1995..2112
Gene:DISC1
Gene Synonym:
Exon (11)2113..6693
Gene:DISC1
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001164540
Organism Homo sapiens (human)
Definition Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant d, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001164540

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
ATGCCAGGCG GGGGTCCTCA GGGCGCCCCA GCCGCCGCCG GCGGCGGCGG CGTGAGCCAC 
CGCGCAGGCA GCCGGGATTG CTTACCACCT GCAGCGTGCT TTCGGAGGCG GCGGCTGGCA
CGGAGGCCGG GCTACATGAG AAGCTCGACA GGGCCTGGGA TCGGGTTCCT TTCCCCAGCA
GTGGGCACAC TGTTCCGGTT CCCAGGAGGG GTGTCTGGCG AGGAGTCCCA CCACTCGGAG
TCCAGGGCCA GACAGTGTGG CCTTGACTCG AGAGGCCTCT TGGTCCGGAG CCCTGTTTCC
AAGAGTGCAG CAGCCCCTAC TGTGACCTCT GTGAGAGGAA CCTCGGCGCA CTTTGGGATT
CAGCTCAGAG GTGGCACCAG ATTGCCTGAC AGGCTTAGCT GGCCGTGTGG CCCTGGGAGT
GCTGGGTGGC AGCAAGAGTT TGCAGCCATG GATAGTTCTG AGACCCTGGA CGCCAGCTGG
GAGGCAGCCT GCAGCGATGG AGCAAGGCGT GTCCGGGCAG CAGGCTCTCT GCCATCAGCA
GAGTTGAGTA GCAACAGCTG CAGCCCTGGC TGTGGCCCTG AGGTCCCCCC AACCCCTCCT
GGCTCTCACA GTGCCTTTAC CTCAAGCTTT AGCTTTATTC GGCTCTCGCT TGGCTCTGCC
GGGGAACGTG GAGAAGCAGA AGGCTGCCCA CCATCCAGAG AGGCTGAGTC CCATTGCCAG
AGCCCCCAGG AGATGGGAGC CAAAGCTGCC AGCTTGGACG GGCCTCACGA GGACCCGCGA
TGTCTCTCTC GGCCCTTCAG TCTCTTGGCT ACACGGGTCT CTGCAGACTT GGCCCAGGCC
GCAAGGAACA GCTCCAGGCC AGAGCGTGAC ATGCATTCTT TACCAGACAT GGACCCTGGC
TCCTCCAGTT CTCTGGATCC CTCACTGGCT GGCTGTGGTG GTGATGGGAG CAGCGGCTCA
GGGGATGCCC ACTCTTGGGA CACCCTGCTC AGGAAATGGG AGCCAGTGCT GCGGGACTGC
CTGCTGAGAA ACCGGAGGCA GATGGAGGTA ATATCCTTAA GATTAAAACT TCAGAAACTT
CAGGAAGATG CAGTTGAGAA TGATGATTAT GATAAAGCTG AGACGTTACA ACAAAGATTA
GAAGACCTGG AACAAGAGAA AATCAGCCTG CACTTTCAAC TTCCTTCAAG GCAGCCAGCT
CTTAGCAGTT TCCTGGGTCA CCTGGCAGCA CAAGTCCAGG CTGCCTTGCG CCGTGGGGCC
ACTCAGCACC TCCAGGAAAG AATAAAATCC CTCAACTTGT CACTTAAAGA AATCACTACT
AAGGTGTGTA TGAGTGAGAA ATTCTGCAGC ACCCTGAGGA AGAAAGTTAA CGATATTGAA
ACCCAACTAC CAGCCTTGCT TGAAGCCAAA ATGCATGCCA TATCAGGAAA CCATTTCTGG
ACGGCTAAAG ACCTCACCGA GGAGATTAGA TCATTAACAT CAGAGAGAGA AGGGCTGGAG
GGACTCCTCA GCAAGCTGTT GGTGTTGAGT TCCAGGAATG TCAAAAAGCT GGGAAGTGTT
AAAGAAGATT ACAACAGACT GAGAAGAGAA GTGGAGCACC AGGAGACTGC CTATGAAACA
AGTGTGAAGG AAAATACTAT GAAGTACATG GAAACACTTA AGAATAAACT GTGCAGCTGC
AAGTGTCCAC TGCTTGGGAA AGTGTGGGAA GCTGACTTGG AAGCTTGTCG ATTGCTTATC
CAGAGCCTAC AGCTCCAGGA AGCCAGGGGA AGCCTGTCTG TAGAAGATGA GAGGCAGATG
GATGACTTAG AGGGAGCTGC TCCTCCTATT CCCCCCAGGC TCCACTCCGA GGATAAAAGG
AAGACCCCTT TGAAGGTATT GGAAGAATGG AAGACTCACC TCATCCCCTC TCTGCACTGT
GCTGGAGGTG AACAGAAAGA GGAATCTTAC ATCCTTTCTG CAGAACTTGG AGAAAAGTGT
GAAGACATAG GCAAGAAGCT ATTGTACTTG GAAGATCAAC TTCACACAGC AATCCACAGT
CATGATGAAG ATCTCATTCA GTCTCTCAGG AGGGAGCTCC AGATGGTGAA GGAAACTCTG
CAGGCCATGA TCCTGCAGCT CCAGCCAGCA AAGGAGGCGG GAGAAAGAGA AGCTGCAGCT
TCCTGCATGA CAGCTGGTGT CCACGAAGCA CAAGCCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu24842
Clone ID Related Accession (Same CDS sequence) NM_001164541
Accession Version NM_001164541.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2088bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product disrupted in schizophrenia 1 protein isoform e
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from FJ804186.1 and BC142622.1. Transcript Variant: This variant (e) lacks an internal exon and two end exons in the 3' region, but has an alternate 3' segment, as compared to variant L. The resulting isoform (e, also known as isoform 15) lacks an internal segment, and has a distinct and shorter C-terminus, as compared to isoform L. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: FJ804186.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
ATGCCAGGCG GGGGTCCTCA GGGCGCCCCA GCCGCCGCCG GCGGCGGCGG CGTGAGCCAC 
CGCGCAGGCA GCCGGGATTG CTTACCACCT GCAGCGTGCT TTCGGAGGCG GCGGCTGGCA
CGGAGGCCGG GCTACATGAG AAGCTCGACA GGGCCTGGGA TCGGGTTCCT TTCCCCAGCA
GTGGGCACAC TGTTCCGGTT CCCAGGAGGG GTGTCTGGCG AGGAGTCCCA CCACTCGGAG
TCCAGGGCCA GACAGTGTGG CCTTGACTCG AGAGGCCTCT TGGTCCGGAG CCCTGTTTCC
AAGAGTGCAG CAGCCCCTAC TGTGACCTCT GTGAGAGGAA CCTCGGCGCA CTTTGGGATT
CAGCTCAGAG GTGGCACCAG ATTGCCTGAC AGGCTTAGCT GGCCGTGTGG CCCTGGGAGT
GCTGGGTGGC AGCAAGAGTT TGCAGCCATG GATAGTTCTG AGACCCTGGA CGCCAGCTGG
GAGGCAGCCT GCAGCGATGG AGCAAGGCGT GTCCGGGCAG CAGGCTCTCT GCCATCAGCA
GAGTTGAGTA GCAACAGCTG CAGCCCTGGC TGTGGCCCTG AGGTCCCCCC AACCCCTCCT
GGCTCTCACA GTGCCTTTAC CTCAAGCTTT AGCTTTATTC GGCTCTCGCT TGGCTCTGCC
GGGGAACGTG GAGAAGCAGA AGGCTGCCCA CCATCCAGAG AGGCTGAGTC CCATTGCCAG
AGCCCCCAGG AGATGGGAGC CAAAGCTGCC AGCTTGGACG GGCCTCACGA GGACCCGCGA
TGTCTCTCTC GGCCCTTCAG TCTCTTGGCT ACACGGGTCT CTGCAGACTT GGCCCAGGCC
GCAAGGAACA GCTCCAGGCC AGAGCGTGAC ATGCATTCTT TACCAGACAT GGACCCTGGC
TCCTCCAGTT CTCTGGATCC CTCACTGGCT GGCTGTGGTG GTGATGGGAG CAGCGGCTCA
GGGGATGCCC ACTCTTGGGA CACCCTGCTC AGGAAATGGG AGCCAGTGCT GCGGGACTGC
CTGCTGAGAA ACCGGAGGCA GATGGAGGTA ATATCCTTAA GATTAAAACT TCAGAAACTT
CAGGAAGATG CAGTTGAGAA TGATGATTAT GATAAAGCTG AGACGTTACA ACAAAGATTA
GAAGACCTGG AACAAGAGAA AATCAGCCTG CACTTTCAAC TTCCTTCAAG GCAGCCAGCT
CTTAGCAGTT TCCTGGGTCA CCTGGCAGCA CAAGTCCAGG CTGCCTTGCG CCGTGGGGCC
ACTCAGCAGG CCAGCGGAGA TGACACCCAC ACCCCACTGA GAATGGAGCC GAGGCTGTTG
GAACCCACTG CTCAGGACAG CTTGCACGTG TCCATCACGA GACGAGACTG GCTTCTTCAG
GAAAAGCAGC AGCTACAGAA AGAAATCGAA GCTCTCCAAG CAAGGATGTT TGTGCTGGAA
GCCAAAGATC AACAGCTGAG AAGGGAAATA GAGGAGCAAG AGCAGCAACT CCAGTGGCAG
GGCTGCGACC TGACCCCACT GGTGGGCCAG CTGTCCCTGG GTCAGCTGCA GGAGGTCAGC
AAGGCCTTGC AGGACACCCT GGCCTCAGCC GGTCAGATTC CCTTCCATGC AGAGCCACCG
GAAACCATAA GGAGCCTCCA GGAAAGAATA AAATCCCTCA ACTTGTCACT TAAAGAAATC
ACTACTAAGG TGTGTATGAG TGAGAAATTC TGCAGCACCC TGAGGAAGAA AGTTAACGAT
ATTGAAACCC AACTACCAGC CTTGCTTGAA GCCAAAATGC ATGCCATATC AGGAAACCAT
TTCTGGACGG CTAAAGACCT CACCGAGGAG ATTAGATCAT TAACATCAGA GAGAGAAGGG
CTGGAGGGAC TCCTCAGCAA GCTGTTGGTG TTGAGTTCCA GGAATGTCAA AAAGCTGGGA
AGTGTTAAAG AAGATTACAA CAGACTGAGA AGAGAAGTGG AGCACCAGGA GACTGCCTAT
GCTGCAAGTG TCCACTGCTT GGGAAAGTGT GGGAAGCTGA CTTGGAAGCT TGTCGATTGC
TTATCCAGAG CCTACAGCTC CAGGAAGCCA GGGGAAGCCT GTCTGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001158013.1
CDS54..2141
Misc Feature(1)1062..2030(+)
Exon (1)1..120
Gene:DISC1
Gene Synonym:
Exon (2)121..1100
Gene:DISC1
Gene Synonym:
Exon (3)1101..1170
Gene:DISC1
Gene Synonym:
Exon (4)1171..1321
Gene:DISC1
Gene Synonym:
Exon (5)1322..1451
Gene:DISC1
Gene Synonym:
Exon (6)1452..1687
Gene:DISC1
Gene Synonym:
Exon (7)1688..1742
Gene:DISC1
Gene Synonym:
Exon (8)1743..1845
Gene:DISC1
Gene Synonym:
Exon (9)1846..2034
Gene:DISC1
Gene Synonym:
Exon (10)2035..2904
Gene:DISC1
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001164541
Organism Homo sapiens (human)
Definition Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant e, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001164541

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
ATGCCAGGCG GGGGTCCTCA GGGCGCCCCA GCCGCCGCCG GCGGCGGCGG CGTGAGCCAC 
CGCGCAGGCA GCCGGGATTG CTTACCACCT GCAGCGTGCT TTCGGAGGCG GCGGCTGGCA
CGGAGGCCGG GCTACATGAG AAGCTCGACA GGGCCTGGGA TCGGGTTCCT TTCCCCAGCA
GTGGGCACAC TGTTCCGGTT CCCAGGAGGG GTGTCTGGCG AGGAGTCCCA CCACTCGGAG
TCCAGGGCCA GACAGTGTGG CCTTGACTCG AGAGGCCTCT TGGTCCGGAG CCCTGTTTCC
AAGAGTGCAG CAGCCCCTAC TGTGACCTCT GTGAGAGGAA CCTCGGCGCA CTTTGGGATT
CAGCTCAGAG GTGGCACCAG ATTGCCTGAC AGGCTTAGCT GGCCGTGTGG CCCTGGGAGT
GCTGGGTGGC AGCAAGAGTT TGCAGCCATG GATAGTTCTG AGACCCTGGA CGCCAGCTGG
GAGGCAGCCT GCAGCGATGG AGCAAGGCGT GTCCGGGCAG CAGGCTCTCT GCCATCAGCA
GAGTTGAGTA GCAACAGCTG CAGCCCTGGC TGTGGCCCTG AGGTCCCCCC AACCCCTCCT
GGCTCTCACA GTGCCTTTAC CTCAAGCTTT AGCTTTATTC GGCTCTCGCT TGGCTCTGCC
GGGGAACGTG GAGAAGCAGA AGGCTGCCCA CCATCCAGAG AGGCTGAGTC CCATTGCCAG
AGCCCCCAGG AGATGGGAGC CAAAGCTGCC AGCTTGGACG GGCCTCACGA GGACCCGCGA
TGTCTCTCTC GGCCCTTCAG TCTCTTGGCT ACACGGGTCT CTGCAGACTT GGCCCAGGCC
GCAAGGAACA GCTCCAGGCC AGAGCGTGAC ATGCATTCTT TACCAGACAT GGACCCTGGC
TCCTCCAGTT CTCTGGATCC CTCACTGGCT GGCTGTGGTG GTGATGGGAG CAGCGGCTCA
GGGGATGCCC ACTCTTGGGA CACCCTGCTC AGGAAATGGG AGCCAGTGCT GCGGGACTGC
CTGCTGAGAA ACCGGAGGCA GATGGAGGTA ATATCCTTAA GATTAAAACT TCAGAAACTT
CAGGAAGATG CAGTTGAGAA TGATGATTAT GATAAAGCTG AGACGTTACA ACAAAGATTA
GAAGACCTGG AACAAGAGAA AATCAGCCTG CACTTTCAAC TTCCTTCAAG GCAGCCAGCT
CTTAGCAGTT TCCTGGGTCA CCTGGCAGCA CAAGTCCAGG CTGCCTTGCG CCGTGGGGCC
ACTCAGCAGG CCAGCGGAGA TGACACCCAC ACCCCACTGA GAATGGAGCC GAGGCTGTTG
GAACCCACTG CTCAGGACAG CTTGCACGTG TCCATCACGA GACGAGACTG GCTTCTTCAG
GAAAAGCAGC AGCTACAGAA AGAAATCGAA GCTCTCCAAG CAAGGATGTT TGTGCTGGAA
GCCAAAGATC AACAGCTGAG AAGGGAAATA GAGGAGCAAG AGCAGCAACT CCAGTGGCAG
GGCTGCGACC TGACCCCACT GGTGGGCCAG CTGTCCCTGG GTCAGCTGCA GGAGGTCAGC
AAGGCCTTGC AGGACACCCT GGCCTCAGCC GGTCAGATTC CCTTCCATGC AGAGCCACCG
GAAACCATAA GGAGCCTCCA GGAAAGAATA AAATCCCTCA ACTTGTCACT TAAAGAAATC
ACTACTAAGG TGTGTATGAG TGAGAAATTC TGCAGCACCC TGAGGAAGAA AGTTAACGAT
ATTGAAACCC AACTACCAGC CTTGCTTGAA GCCAAAATGC ATGCCATATC AGGAAACCAT
TTCTGGACGG CTAAAGACCT CACCGAGGAG ATTAGATCAT TAACATCAGA GAGAGAAGGG
CTGGAGGGAC TCCTCAGCAA GCTGTTGGTG TTGAGTTCCA GGAATGTCAA AAAGCTGGGA
AGTGTTAAAG AAGATTACAA CAGACTGAGA AGAGAAGTGG AGCACCAGGA GACTGCCTAT
GCTGCAAGTG TCCACTGCTT GGGAAAGTGT GGGAAGCTGA CTTGGAAGCT TGTCGATTGC
TTATCCAGAG CCTACAGCTC CAGGAAGCCA GGGGAAGCCT GTCTGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu25031
Clone ID Related Accession (Same CDS sequence) NM_001164542
Accession Version NM_001164542.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2046bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product disrupted in schizophrenia 1 protein isoform f
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from FJ804187.1. Transcript Variant: This variant (f) lacks several 3' exons but has an alternate 3' segment, as compared to variant L. The resulting isoform (f, also known as isoform 16) is C-terminal truncated, as compared to isoform L. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: FJ804187.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2142348 [ECO:0000348] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
ATGCCAGGCG GGGGTCCTCA GGGCGCCCCA GCCGCCGCCG GCGGCGGCGG CGTGAGCCAC 
CGCGCAGGCA GCCGGGATTG CTTACCACCT GCAGCGTGCT TTCGGAGGCG GCGGCTGGCA
CGGAGGCCGG GCTACATGAG AAGCTCGACA GGGCCTGGGA TCGGGTTCCT TTCCCCAGCA
GTGGGCACAC TGTTCCGGTT CCCAGGAGGG GTGTCTGGCG AGGAGTCCCA CCACTCGGAG
TCCAGGGCCA GACAGTGTGG CCTTGACTCG AGAGGCCTCT TGGTCCGGAG CCCTGTTTCC
AAGAGTGCAG CAGCCCCTAC TGTGACCTCT GTGAGAGGAA CCTCGGCGCA CTTTGGGATT
CAGCTCAGAG GTGGCACCAG ATTGCCTGAC AGGCTTAGCT GGCCGTGTGG CCCTGGGAGT
GCTGGGTGGC AGCAAGAGTT TGCAGCCATG GATAGTTCTG AGACCCTGGA CGCCAGCTGG
GAGGCAGCCT GCAGCGATGG AGCAAGGCGT GTCCGGGCAG CAGGCTCTCT GCCATCAGCA
GAGTTGAGTA GCAACAGCTG CAGCCCTGGC TGTGGCCCTG AGGTCCCCCC AACCCCTCCT
GGCTCTCACA GTGCCTTTAC CTCAAGCTTT AGCTTTATTC GGCTCTCGCT TGGCTCTGCC
GGGGAACGTG GAGAAGCAGA AGGCTGCCCA CCATCCAGAG AGGCTGAGTC CCATTGCCAG
AGCCCCCAGG AGATGGGAGC CAAAGCTGCC AGCTTGGACG GGCCTCACGA GGACCCGCGA
TGTCTCTCTC GGCCCTTCAG TCTCTTGGCT ACACGGGTCT CTGCAGACTT GGCCCAGGCC
GCAAGGAACA GCTCCAGGCC AGAGCGTGAC ATGCATTCTT TACCAGACAT GGACCCTGGC
TCCTCCAGTT CTCTGGATCC CTCACTGGCT GGCTGTGGTG GTGATGGGAG CAGCGGCTCA
GGGGATGCCC ACTCTTGGGA CACCCTGCTC AGGAAATGGG AGCCAGTGCT GCGGGACTGC
CTGCTGAGAA ACCGGAGGCA GATGGAGGTA ATATCCTTAA GATTAAAACT TCAGAAACTT
CAGGAAGATG CAGTTGAGAA TGATGATTAT GATAAAGCTG AGACGTTACA ACAAAGATTA
GAAGACCTGG AACAAGAGAA AATCAGCCTG CACTTTCAAC TTCCTTCAAG GCAGCCAGCT
CTTAGCAGTT TCCTGGGTCA CCTGGCAGCA CAAGTCCAGG CTGCCTTGCG CCGTGGGGCC
ACTCAGCAGG CCAGCGGAGA TGACACCCAC ACCCCACTGA GAATGGAGCC GAGGCTGTTG
GAACCCACTG CTCAGGACAG CTTGCACGTG TCCATCACGA GACGAGACTG GCTTCTTCAG
GAAAAGCAGC AGCTACAGAA AGAAATCGAA GCTCTCCAAG CAAGGATGTT TGTGCTGGAA
GCCAAAGATC AACAGCTGAG AAGGGAAATA GAGGAGCAAG AGCAGCAACT CCAGTGGCAG
GGCTGCGACC TGACCCCACT GGTGGGCCAG CTGTCCCTGG GTCAGCTGCA GGAGGTCAGC
AAGGCCTTGC AGGACACCCT GGCCTCAGCC GGTCAGATTC CCTTCCATGC AGAGCCACCG
GAAACCATAA GGAGCCTCCA GGAAAGAATA AAATCCCTCA ACTTGTCACT TAAAGAAATC
ACTACTAAGG TGTGTATGAG TGAGAAATTC TGCAGCACCC TGAGGAAGAA AGTTAACGAT
ATTGAAACCC AACTACCAGC CTTGCTTGAA GCCAAAATGC ATGCCATATC AGGAAACCAT
TTCTGGACGG CTAAAGACCT CACCGAGGAG ATTAGATCAT TAACATCAGA GAGAGAAGGG
CTGGAGGGAC TCCTCAGCAA GCTGTTGGTG TTGAGTTCCA GGAATGTCAA AAAGCTGGGA
AGTGTTAAAG AAGATTACAA CAGACTGAGA AGAGAAGTGG AGCACCAGGA GACTGCCTAT
GAAACAAGTG TGAAGGAAAA TACTATGAAG TACATGGAAA CACTTAAGAA TAAACTGTGC
AGGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001158014.1
CDS54..2099
Misc Feature(1)54..929(+)
Misc Feature(2)1062..2087(+)
Misc Feature(3)1371..1844(+)
Exon (1)1..120
Gene:DISC1
Gene Synonym:
Exon (2)121..1100
Gene:DISC1
Gene Synonym:
Exon (3)1101..1170
Gene:DISC1
Gene Synonym:
Exon (4)1171..1321
Gene:DISC1
Gene Synonym:
Exon (5)1322..1451
Gene:DISC1
Gene Synonym:
Exon (6)1452..1687
Gene:DISC1
Gene Synonym:
Exon (7)1688..1742
Gene:DISC1
Gene Synonym:
Exon (8)1743..1845
Gene:DISC1
Gene Synonym:
Exon (9)1846..2034
Gene:DISC1
Gene Synonym:
Exon (10)2035..2710
Gene:DISC1
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001164542
Organism Homo sapiens (human)
Definition Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant f, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001164542

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
ATGCCAGGCG GGGGTCCTCA GGGCGCCCCA GCCGCCGCCG GCGGCGGCGG CGTGAGCCAC 
CGCGCAGGCA GCCGGGATTG CTTACCACCT GCAGCGTGCT TTCGGAGGCG GCGGCTGGCA
CGGAGGCCGG GCTACATGAG AAGCTCGACA GGGCCTGGGA TCGGGTTCCT TTCCCCAGCA
GTGGGCACAC TGTTCCGGTT CCCAGGAGGG GTGTCTGGCG AGGAGTCCCA CCACTCGGAG
TCCAGGGCCA GACAGTGTGG CCTTGACTCG AGAGGCCTCT TGGTCCGGAG CCCTGTTTCC
AAGAGTGCAG CAGCCCCTAC TGTGACCTCT GTGAGAGGAA CCTCGGCGCA CTTTGGGATT
CAGCTCAGAG GTGGCACCAG ATTGCCTGAC AGGCTTAGCT GGCCGTGTGG CCCTGGGAGT
GCTGGGTGGC AGCAAGAGTT TGCAGCCATG GATAGTTCTG AGACCCTGGA CGCCAGCTGG
GAGGCAGCCT GCAGCGATGG AGCAAGGCGT GTCCGGGCAG CAGGCTCTCT GCCATCAGCA
GAGTTGAGTA GCAACAGCTG CAGCCCTGGC TGTGGCCCTG AGGTCCCCCC AACCCCTCCT
GGCTCTCACA GTGCCTTTAC CTCAAGCTTT AGCTTTATTC GGCTCTCGCT TGGCTCTGCC
GGGGAACGTG GAGAAGCAGA AGGCTGCCCA CCATCCAGAG AGGCTGAGTC CCATTGCCAG
AGCCCCCAGG AGATGGGAGC CAAAGCTGCC AGCTTGGACG GGCCTCACGA GGACCCGCGA
TGTCTCTCTC GGCCCTTCAG TCTCTTGGCT ACACGGGTCT CTGCAGACTT GGCCCAGGCC
GCAAGGAACA GCTCCAGGCC AGAGCGTGAC ATGCATTCTT TACCAGACAT GGACCCTGGC
TCCTCCAGTT CTCTGGATCC CTCACTGGCT GGCTGTGGTG GTGATGGGAG CAGCGGCTCA
GGGGATGCCC ACTCTTGGGA CACCCTGCTC AGGAAATGGG AGCCAGTGCT GCGGGACTGC
CTGCTGAGAA ACCGGAGGCA GATGGAGGTA ATATCCTTAA GATTAAAACT TCAGAAACTT
CAGGAAGATG CAGTTGAGAA TGATGATTAT GATAAAGCTG AGACGTTACA ACAAAGATTA
GAAGACCTGG AACAAGAGAA AATCAGCCTG CACTTTCAAC TTCCTTCAAG GCAGCCAGCT
CTTAGCAGTT TCCTGGGTCA CCTGGCAGCA CAAGTCCAGG CTGCCTTGCG CCGTGGGGCC
ACTCAGCAGG CCAGCGGAGA TGACACCCAC ACCCCACTGA GAATGGAGCC GAGGCTGTTG
GAACCCACTG CTCAGGACAG CTTGCACGTG TCCATCACGA GACGAGACTG GCTTCTTCAG
GAAAAGCAGC AGCTACAGAA AGAAATCGAA GCTCTCCAAG CAAGGATGTT TGTGCTGGAA
GCCAAAGATC AACAGCTGAG AAGGGAAATA GAGGAGCAAG AGCAGCAACT CCAGTGGCAG
GGCTGCGACC TGACCCCACT GGTGGGCCAG CTGTCCCTGG GTCAGCTGCA GGAGGTCAGC
AAGGCCTTGC AGGACACCCT GGCCTCAGCC GGTCAGATTC CCTTCCATGC AGAGCCACCG
GAAACCATAA GGAGCCTCCA GGAAAGAATA AAATCCCTCA ACTTGTCACT TAAAGAAATC
ACTACTAAGG TGTGTATGAG TGAGAAATTC TGCAGCACCC TGAGGAAGAA AGTTAACGAT
ATTGAAACCC AACTACCAGC CTTGCTTGAA GCCAAAATGC ATGCCATATC AGGAAACCAT
TTCTGGACGG CTAAAGACCT CACCGAGGAG ATTAGATCAT TAACATCAGA GAGAGAAGGG
CTGGAGGGAC TCCTCAGCAA GCTGTTGGTG TTGAGTTCCA GGAATGTCAA AAAGCTGGGA
AGTGTTAAAG AAGATTACAA CAGACTGAGA AGAGAAGTGG AGCACCAGGA GACTGCCTAT
GAAACAAGTG TGAAGGAAAA TACTATGAAG TACATGGAAA CACTTAAGAA TAAACTGTGC
AGGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu24946
Clone ID Related Accession (Same CDS sequence) NM_001164544
Accession Version NM_001164544.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1989bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product disrupted in schizophrenia 1 protein isoform g
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from FJ804199.1. Transcript Variant: This variant (g) lacks multiple 3' exons but has an alternate 3' segment, as compared to variant L. The resulting isoform (g, also known as isoform 29) is much shorter and has a distinct C-terminus, as compared to isoform L. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: FJ804199.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2142348 [ECO:0000348] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
ATGCCAGGCG GGGGTCCTCA GGGCGCCCCA GCCGCCGCCG GCGGCGGCGG CGTGAGCCAC 
CGCGCAGGCA GCCGGGATTG CTTACCACCT GCAGCGTGCT TTCGGAGGCG GCGGCTGGCA
CGGAGGCCGG GCTACATGAG AAGCTCGACA GGGCCTGGGA TCGGGTTCCT TTCCCCAGCA
GTGGGCACAC TGTTCCGGTT CCCAGGAGGG GTGTCTGGCG AGGAGTCCCA CCACTCGGAG
TCCAGGGCCA GACAGTGTGG CCTTGACTCG AGAGGCCTCT TGGTCCGGAG CCCTGTTTCC
AAGAGTGCAG CAGCCCCTAC TGTGACCTCT GTGAGAGGAA CCTCGGCGCA CTTTGGGATT
CAGCTCAGAG GTGGCACCAG ATTGCCTGAC AGGCTTAGCT GGCCGTGTGG CCCTGGGAGT
GCTGGGTGGC AGCAAGAGTT TGCAGCCATG GATAGTTCTG AGACCCTGGA CGCCAGCTGG
GAGGCAGCCT GCAGCGATGG AGCAAGGCGT GTCCGGGCAG CAGGCTCTCT GCCATCAGCA
GAGTTGAGTA GCAACAGCTG CAGCCCTGGC TGTGGCCCTG AGGTCCCCCC AACCCCTCCT
GGCTCTCACA GTGCCTTTAC CTCAAGCTTT AGCTTTATTC GGCTCTCGCT TGGCTCTGCC
GGGGAACGTG GAGAAGCAGA AGGCTGCCCA CCATCCAGAG AGGCTGAGTC CCATTGCCAG
AGCCCCCAGG AGATGGGAGC CAAAGCTGCC AGCTTGGACG GGCCTCACGA GGACCCGCGA
TGTCTCTCTC GGCCCTTCAG TCTCTTGGCT ACACGGGTCT CTGCAGACTT GGCCCAGGCC
GCAAGGAACA GCTCCAGGCC AGAGCGTGAC ATGCATTCTT TACCAGACAT GGACCCTGGC
TCCTCCAGTT CTCTGGATCC CTCACTGGCT GGCTGTGGTG GTGATGGGAG CAGCGGCTCA
GGGGATGCCC ACTCTTGGGA CACCCTGCTC AGGAAATGGG AGCCAGTGCT GCGGGACTGC
CTGCTGAGAA ACCGGAGGCA GATGGAGGTA ATATCCTTAA GATTAAAACT TCAGAAACTT
CAGGAAGATG CAGTTGAGAA TGATGATTAT GATAAAGCTG AGACGTTACA ACAAAGATTA
GAAGACCTGG AACAAGAGAA AATCAGCCTG CACTTTCAAC TTCCTTCAAG GCAGCCAGCT
CTTAGCAGTT TCCTGGGTCA CCTGGCAGCA CAAGTCCAGG CTGCCTTGCG CCGTGGGGCC
ACTCAGCAGG CCAGCGGAGA TGACACCCAC ACCCCACTGA GAATGGAGCC GAGGCTGTTG
GAACCCACTG CTCAGGACAG CTTGCACGTG TCCATCACGA GACGAGACTG GCTTCTTCAG
GAAAAGCAGC AGCTACAGAA AGAAATCGAA GCTCTCCAAG CAAGGATGTT TGTGCTGGAA
GCCAAAGATC AACAGCTGAG AAGGGAAATA GAGGAGCAAG AGCAGCAACT CCAGTGGCAG
GGCTGCGACC TGACCCCACT GGTGGGCCAG CTGTCCCTGG GTCAGCTGCA GGAGGTCAGC
AAGGCCTTGC AGGACACCCT GGCCTCAGCC GGTCAGATTC CCTTCCATGC AGAGCCACCG
GAAACCATAA GGAGCCTCCA GGAAAGAATA AAATCCCTCA ACTTGTCACT TAAAGAAATC
ACTACTAAGG TGTGTATGAG TGAGAAATTC TGCAGCACCC TGAGGAAGAA AGTTAACGAT
ATTGAAACCC AACTACCAGC CTTGCTTGAA GCCAAAATGC ATGCCATATC AGGAAACCAT
TTCTGGACGG CTAAAGACCT CACCGAGGAG ATTAGATCAT TAACATCAGA GAGAGAAGGG
CTGGAGGGAC TCCTCAGCAA GCTGTTGGTG TTGAGTTCCA GGAATGTCAA AAAGCTGGGA
AGTGTTAAAG AAGATTACAA CAGACTGAGA AGAGAAGTGG AGCACCAGGA GACTGCCTAT
GGTAGGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001158016.1
CDS54..2042
Misc Feature(1)54..929(+)
Misc Feature(2)1062..2030(+)
Misc Feature(3)1371..1844(+)
Exon (1)1..120
Gene:DISC1
Gene Synonym:
Exon (2)121..1100
Gene:DISC1
Gene Synonym:
Exon (3)1101..1170
Gene:DISC1
Gene Synonym:
Exon (4)1171..1321
Gene:DISC1
Gene Synonym:
Exon (5)1322..1451
Gene:DISC1
Gene Synonym:
Exon (6)1452..1687
Gene:DISC1
Gene Synonym:
Exon (7)1688..1742
Gene:DISC1
Gene Synonym:
Exon (8)1743..1845
Gene:DISC1
Gene Synonym:
Exon (9)1846..2761
Gene:DISC1
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001164544
Organism Homo sapiens (human)
Definition Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant g, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001164544

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
ATGCCAGGCG GGGGTCCTCA GGGCGCCCCA GCCGCCGCCG GCGGCGGCGG CGTGAGCCAC 
CGCGCAGGCA GCCGGGATTG CTTACCACCT GCAGCGTGCT TTCGGAGGCG GCGGCTGGCA
CGGAGGCCGG GCTACATGAG AAGCTCGACA GGGCCTGGGA TCGGGTTCCT TTCCCCAGCA
GTGGGCACAC TGTTCCGGTT CCCAGGAGGG GTGTCTGGCG AGGAGTCCCA CCACTCGGAG
TCCAGGGCCA GACAGTGTGG CCTTGACTCG AGAGGCCTCT TGGTCCGGAG CCCTGTTTCC
AAGAGTGCAG CAGCCCCTAC TGTGACCTCT GTGAGAGGAA CCTCGGCGCA CTTTGGGATT
CAGCTCAGAG GTGGCACCAG ATTGCCTGAC AGGCTTAGCT GGCCGTGTGG CCCTGGGAGT
GCTGGGTGGC AGCAAGAGTT TGCAGCCATG GATAGTTCTG AGACCCTGGA CGCCAGCTGG
GAGGCAGCCT GCAGCGATGG AGCAAGGCGT GTCCGGGCAG CAGGCTCTCT GCCATCAGCA
GAGTTGAGTA GCAACAGCTG CAGCCCTGGC TGTGGCCCTG AGGTCCCCCC AACCCCTCCT
GGCTCTCACA GTGCCTTTAC CTCAAGCTTT AGCTTTATTC GGCTCTCGCT TGGCTCTGCC
GGGGAACGTG GAGAAGCAGA AGGCTGCCCA CCATCCAGAG AGGCTGAGTC CCATTGCCAG
AGCCCCCAGG AGATGGGAGC CAAAGCTGCC AGCTTGGACG GGCCTCACGA GGACCCGCGA
TGTCTCTCTC GGCCCTTCAG TCTCTTGGCT ACACGGGTCT CTGCAGACTT GGCCCAGGCC
GCAAGGAACA GCTCCAGGCC AGAGCGTGAC ATGCATTCTT TACCAGACAT GGACCCTGGC
TCCTCCAGTT CTCTGGATCC CTCACTGGCT GGCTGTGGTG GTGATGGGAG CAGCGGCTCA
GGGGATGCCC ACTCTTGGGA CACCCTGCTC AGGAAATGGG AGCCAGTGCT GCGGGACTGC
CTGCTGAGAA ACCGGAGGCA GATGGAGGTA ATATCCTTAA GATTAAAACT TCAGAAACTT
CAGGAAGATG CAGTTGAGAA TGATGATTAT GATAAAGCTG AGACGTTACA ACAAAGATTA
GAAGACCTGG AACAAGAGAA AATCAGCCTG CACTTTCAAC TTCCTTCAAG GCAGCCAGCT
CTTAGCAGTT TCCTGGGTCA CCTGGCAGCA CAAGTCCAGG CTGCCTTGCG CCGTGGGGCC
ACTCAGCAGG CCAGCGGAGA TGACACCCAC ACCCCACTGA GAATGGAGCC GAGGCTGTTG
GAACCCACTG CTCAGGACAG CTTGCACGTG TCCATCACGA GACGAGACTG GCTTCTTCAG
GAAAAGCAGC AGCTACAGAA AGAAATCGAA GCTCTCCAAG CAAGGATGTT TGTGCTGGAA
GCCAAAGATC AACAGCTGAG AAGGGAAATA GAGGAGCAAG AGCAGCAACT CCAGTGGCAG
GGCTGCGACC TGACCCCACT GGTGGGCCAG CTGTCCCTGG GTCAGCTGCA GGAGGTCAGC
AAGGCCTTGC AGGACACCCT GGCCTCAGCC GGTCAGATTC CCTTCCATGC AGAGCCACCG
GAAACCATAA GGAGCCTCCA GGAAAGAATA AAATCCCTCA ACTTGTCACT TAAAGAAATC
ACTACTAAGG TGTGTATGAG TGAGAAATTC TGCAGCACCC TGAGGAAGAA AGTTAACGAT
ATTGAAACCC AACTACCAGC CTTGCTTGAA GCCAAAATGC ATGCCATATC AGGAAACCAT
TTCTGGACGG CTAAAGACCT CACCGAGGAG ATTAGATCAT TAACATCAGA GAGAGAAGGG
CTGGAGGGAC TCCTCAGCAA GCTGTTGGTG TTGAGTTCCA GGAATGTCAA AAAGCTGGGA
AGTGTTAAAG AAGATTACAA CAGACTGAGA AGAGAAGTGG AGCACCAGGA GACTGCCTAT
GGTAGGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu24760
Clone ID Related Accession (Same CDS sequence) NM_001164545
Accession Version NM_001164545.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1740bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product disrupted in schizophrenia 1 protein isoform h
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from FJ804205.1. Transcript Variant: This variant (h) lacks an internal exon and multiple 3' exons but has an alternate 3' segment, as compared to variant L. The resulting isoform (h, also known as isoform 35) is much shorter and has a distict C-terminus, as compared to isoform L. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: FJ804205.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
ATGCCAGGCG GGGGTCCTCA GGGCGCCCCA GCCGCCGCCG GCGGCGGCGG CGTGAGCCAC 
CGCGCAGGCA GCCGGGATTG CTTACCACCT GCAGCGTGCT TTCGGAGGCG GCGGCTGGCA
CGGAGGCCGG GCTACATGAG AAGCTCGACA GGGCCTGGGA TCGGGTTCCT TTCCCCAGCA
GTGGGCACAC TGTTCCGGTT CCCAGGAGGG GTGTCTGGCG AGGAGTCCCA CCACTCGGAG
TCCAGGGCCA GACAGTGTGG CCTTGACTCG AGAGGCCTCT TGGTCCGGAG CCCTGTTTCC
AAGAGTGCAG CAGCCCCTAC TGTGACCTCT GTGAGAGGAA CCTCGGCGCA CTTTGGGATT
CAGCTCAGAG GTGGCACCAG ATTGCCTGAC AGGCTTAGCT GGCCGTGTGG CCCTGGGAGT
GCTGGGTGGC AGCAAGAGTT TGCAGCCATG GATAGTTCTG AGACCCTGGA CGCCAGCTGG
GAGGCAGCCT GCAGCGATGG AGCAAGGCGT GTCCGGGCAG CAGGCTCTCT GCCATCAGCA
GAGTTGAGTA GCAACAGCTG CAGCCCTGGC TGTGGCCCTG AGGTCCCCCC AACCCCTCCT
GGCTCTCACA GTGCCTTTAC CTCAAGCTTT AGCTTTATTC GGCTCTCGCT TGGCTCTGCC
GGGGAACGTG GAGAAGCAGA AGGCTGCCCA CCATCCAGAG AGGCTGAGTC CCATTGCCAG
AGCCCCCAGG AGATGGGAGC CAAAGCTGCC AGCTTGGACG GGCCTCACGA GGACCCGCGA
TGTCTCTCTC GGCCCTTCAG TCTCTTGGCT ACACGGGTCT CTGCAGACTT GGCCCAGGCC
GCAAGGAACA GCTCCAGGCC AGAGCGTGAC ATGCATTCTT TACCAGACAT GGACCCTGGC
TCCTCCAGTT CTCTGGATCC CTCACTGGCT GGCTGTGGTG GTGATGGGAG CAGCGGCTCA
GGGGATGCCC ACTCTTGGGA CACCCTGCTC AGGAAATGGG AGCCAGTGCT GCGGGACTGC
CTGCTGAGAA ACCGGAGGCA GATGGAGGTA ATATCCTTAA GATTAAAACT TCAGAAACTT
CAGGAAGATG CAGTTGAGAA TGATGATTAT GATAAAGCTG AGACGTTACA ACAAAGATTA
GAAGACCTGG AACAAGAGAA AATCAGCCTG CACTTTCAAC TTCCTTCAAG GCAGCCAGCT
CTTAGCAGTT TCCTGGGTCA CCTGGCAGCA CAAGTCCAGG CTGCCTTGCG CCGTGGGGCC
ACTCAGCAGG CCAGCGGAGA TGACACCCAC ACCCCACTGA GAATGGAGCC GAGGCTGTTG
GAACCCACTG CTCAGGACAG CTTGCACGTG TCCATCACGA GACGAGACTG GCTTCTTCAG
GAAAAGCAGC AGCTACAGAA AGAAATCGAA GCTCTCCAAG CAAGGATGTT TGTGCTGGAA
GCCAAAGATC AACAGCTGAG AAGGGAAATA GAGGAGCAAG AGCAGCAACT CCAGTGGCAG
GGCTGCGACC TGACCCCACT GGTGGGCCAG CTGTCCCTGG GTCAGCTGCA GGAGGTCAGC
AAGGCCTTGC AGGACACCCT GGCCTCAGCC GGTCAGATTC CCTTCCATGC AGAGCCACCG
GAAACCATAA GGAGCCTCCA GGAAAGAATA AAATCCCTCA ACTTGTCACT TAAAGAAATC
ACTACTAAGG AAACCATTTC TGGACGGCTA AAGACCTCAC CGAGGAGATT AGATCATTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001158017.1
CDS54..1793
Misc Feature(1)54..929(+)
Misc Feature(2)1089..>1766(+)
Exon (1)1..120
Gene:DISC1
Gene Synonym:
Exon (2)121..1100
Gene:DISC1
Gene Synonym:
Exon (3)1101..1170
Gene:DISC1
Gene Synonym:
Exon (4)1171..1321
Gene:DISC1
Gene Synonym:
Exon (5)1322..1451
Gene:DISC1
Gene Synonym:
Exon (6)1452..1687
Gene:DISC1
Gene Synonym:
Exon (7)1688..1742
Gene:DISC1
Gene Synonym:
Exon (8)1743..2658
Gene:DISC1
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001164545
Organism Homo sapiens (human)
Definition Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant h, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001164545

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
ATGCCAGGCG GGGGTCCTCA GGGCGCCCCA GCCGCCGCCG GCGGCGGCGG CGTGAGCCAC 
CGCGCAGGCA GCCGGGATTG CTTACCACCT GCAGCGTGCT TTCGGAGGCG GCGGCTGGCA
CGGAGGCCGG GCTACATGAG AAGCTCGACA GGGCCTGGGA TCGGGTTCCT TTCCCCAGCA
GTGGGCACAC TGTTCCGGTT CCCAGGAGGG GTGTCTGGCG AGGAGTCCCA CCACTCGGAG
TCCAGGGCCA GACAGTGTGG CCTTGACTCG AGAGGCCTCT TGGTCCGGAG CCCTGTTTCC
AAGAGTGCAG CAGCCCCTAC TGTGACCTCT GTGAGAGGAA CCTCGGCGCA CTTTGGGATT
CAGCTCAGAG GTGGCACCAG ATTGCCTGAC AGGCTTAGCT GGCCGTGTGG CCCTGGGAGT
GCTGGGTGGC AGCAAGAGTT TGCAGCCATG GATAGTTCTG AGACCCTGGA CGCCAGCTGG
GAGGCAGCCT GCAGCGATGG AGCAAGGCGT GTCCGGGCAG CAGGCTCTCT GCCATCAGCA
GAGTTGAGTA GCAACAGCTG CAGCCCTGGC TGTGGCCCTG AGGTCCCCCC AACCCCTCCT
GGCTCTCACA GTGCCTTTAC CTCAAGCTTT AGCTTTATTC GGCTCTCGCT TGGCTCTGCC
GGGGAACGTG GAGAAGCAGA AGGCTGCCCA CCATCCAGAG AGGCTGAGTC CCATTGCCAG
AGCCCCCAGG AGATGGGAGC CAAAGCTGCC AGCTTGGACG GGCCTCACGA GGACCCGCGA
TGTCTCTCTC GGCCCTTCAG TCTCTTGGCT ACACGGGTCT CTGCAGACTT GGCCCAGGCC
GCAAGGAACA GCTCCAGGCC AGAGCGTGAC ATGCATTCTT TACCAGACAT GGACCCTGGC
TCCTCCAGTT CTCTGGATCC CTCACTGGCT GGCTGTGGTG GTGATGGGAG CAGCGGCTCA
GGGGATGCCC ACTCTTGGGA CACCCTGCTC AGGAAATGGG AGCCAGTGCT GCGGGACTGC
CTGCTGAGAA ACCGGAGGCA GATGGAGGTA ATATCCTTAA GATTAAAACT TCAGAAACTT
CAGGAAGATG CAGTTGAGAA TGATGATTAT GATAAAGCTG AGACGTTACA ACAAAGATTA
GAAGACCTGG AACAAGAGAA AATCAGCCTG CACTTTCAAC TTCCTTCAAG GCAGCCAGCT
CTTAGCAGTT TCCTGGGTCA CCTGGCAGCA CAAGTCCAGG CTGCCTTGCG CCGTGGGGCC
ACTCAGCAGG CCAGCGGAGA TGACACCCAC ACCCCACTGA GAATGGAGCC GAGGCTGTTG
GAACCCACTG CTCAGGACAG CTTGCACGTG TCCATCACGA GACGAGACTG GCTTCTTCAG
GAAAAGCAGC AGCTACAGAA AGAAATCGAA GCTCTCCAAG CAAGGATGTT TGTGCTGGAA
GCCAAAGATC AACAGCTGAG AAGGGAAATA GAGGAGCAAG AGCAGCAACT CCAGTGGCAG
GGCTGCGACC TGACCCCACT GGTGGGCCAG CTGTCCCTGG GTCAGCTGCA GGAGGTCAGC
AAGGCCTTGC AGGACACCCT GGCCTCAGCC GGTCAGATTC CCTTCCATGC AGAGCCACCG
GAAACCATAA GGAGCCTCCA GGAAAGAATA AAATCCCTCA ACTTGTCACT TAAAGAAATC
ACTACTAAGG AAACCATTTC TGGACGGCTA AAGACCTCAC CGAGGAGATT AGATCATTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu24840
Clone ID Related Accession (Same CDS sequence) NM_001164546 , NM_001164547
Accession Version NM_001164546.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1680bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product disrupted in schizophrenia 1 protein isoform i
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from FJ804190.1. Transcript Variant: This variant (i) lacks three internal exons and three 3' exons but has an alternate 3' segment, as compared to variant L. Variants i and j encode the same isoform (i), which is much shorter and has a distinct C-terminus, as compared to isoform L. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: FJ804190.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1968540, SAMEA2142348 [ECO:0000350] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
ATGCCAGGCG GGGGTCCTCA GGGCGCCCCA GCCGCCGCCG GCGGCGGCGG CGTGAGCCAC 
CGCGCAGGCA GCCGGGATTG CTTACCACCT GCAGCGTGCT TTCGGAGGCG GCGGCTGGCA
CGGAGGCCGG GCTACATGAG AAGCTCGACA GGGCCTGGGA TCGGGTTCCT TTCCCCAGCA
GTGGGCACAC TGTTCCGGTT CCCAGGAGGG GTGTCTGGCG AGGAGTCCCA CCACTCGGAG
TCCAGGGCCA GACAGTGTGG CCTTGACTCG AGAGGCCTCT TGGTCCGGAG CCCTGTTTCC
AAGAGTGCAG CAGCCCCTAC TGTGACCTCT GTGAGAGGAA CCTCGGCGCA CTTTGGGATT
CAGCTCAGAG GTGGCACCAG ATTGCCTGAC AGGCTTAGCT GGCCGTGTGG CCCTGGGAGT
GCTGGGTGGC AGCAAGAGTT TGCAGCCATG GATAGTTCTG AGACCCTGGA CGCCAGCTGG
GAGGCAGCCT GCAGCGATGG AGCAAGGCGT GTCCGGGCAG CAGGCTCTCT GCCATCAGCA
GAGTTGAGTA GCAACAGCTG CAGCCCTGGC TGTGGCCCTG AGGTCCCCCC AACCCCTCCT
GGCTCTCACA GTGCCTTTAC CTCAAGCTTT AGCTTTATTC GGCTCTCGCT TGGCTCTGCC
GGGGAACGTG GAGAAGCAGA AGGCTGCCCA CCATCCAGAG AGGCTGAGTC CCATTGCCAG
AGCCCCCAGG AGATGGGAGC CAAAGCTGCC AGCTTGGACG GGCCTCACGA GGACCCGCGA
TGTCTCTCTC GGCCCTTCAG TCTCTTGGCT ACACGGGTCT CTGCAGACTT GGCCCAGGCC
GCAAGGAACA GCTCCAGGCC AGAGCGTGAC ATGCATTCTT TACCAGACAT GGACCCTGGC
TCCTCCAGTT CTCTGGATCC CTCACTGGCT GGCTGTGGTG GTGATGGGAG CAGCGGCTCA
GGGGATGCCC ACTCTTGGGA CACCCTGCTC AGGAAATGGG AGCCAGTGCT GCGGGACTGC
CTGCTGAGAA ACCGGAGGCA GATGGAGGTA ATATCCTTAA GATTAAAACT TCAGAAACTT
CAGGAAGATG CAGTTGAGAA TGATGATTAT GATAAAGCTG AGACGTTACA ACAAAGATTA
GAAGACCTGG AACAAGAGAA AATCAGCCTG CACTTTCAAC TTCCTTCAAG GCAGCCAGCT
CTTAGCAGTT TCCTGGGTCA CCTGGCAGCA CAAGTCCAGG CTGCCTTGCG CCGTGGGGCC
ACTCAGCAGG CCAGCGGAGA TGACACCCAC ACCCCACTGA GAATGGAGCC GAGGCTGTTG
GAACCCACTG CTCAGGACAG CTTGCACGTG TCCATCACGA GACGAGACTG GCTTCTTCAG
GAAAAGCAGC AGCTACAGAA AGAAATCGAA GCTCTCCAAG CAAGGATGTT TGTGCTGGAA
GCCAAAGATC AACAGCTGAG AAGGGAAATA GAGGAGCAAG AGCAGCAACT CCAGTGGCAG
GGCTGCGACC TGACCCCACT GGTGGGCCAG CTGTCCCTGG GTCAGCTGCA GGAGGTCAGC
AAGGCCTTGC AGGACACCCT GGCCTCAGCC GGTCAGATTC CCTTCCATGC AGAGCCACCG
GAAACCATAA GGAGAAACAA GTGTGAAGGA AAATACTATG AAGTACATGG AAACACTTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001158018.1
CDS54..1733
Misc Feature(1)54..929(+)
Misc Feature(2)1074..1517(+)
Exon (1)1..120
Gene:DISC1
Gene Synonym:
Exon (2)121..1100
Gene:DISC1
Gene Synonym:
Exon (3)1101..1170
Gene:DISC1
Gene Synonym:
Exon (4)1171..1321
Gene:DISC1
Gene Synonym:
Exon (5)1322..1451
Gene:DISC1
Gene Synonym:
Exon (6)1452..1687
Gene:DISC1
Gene Synonym:
Exon (7)1688..2363
Gene:DISC1
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001164546
Organism Homo sapiens (human)
Definition Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant i, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001164546

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
ATGCCAGGCG GGGGTCCTCA GGGCGCCCCA GCCGCCGCCG GCGGCGGCGG CGTGAGCCAC 
CGCGCAGGCA GCCGGGATTG CTTACCACCT GCAGCGTGCT TTCGGAGGCG GCGGCTGGCA
CGGAGGCCGG GCTACATGAG AAGCTCGACA GGGCCTGGGA TCGGGTTCCT TTCCCCAGCA
GTGGGCACAC TGTTCCGGTT CCCAGGAGGG GTGTCTGGCG AGGAGTCCCA CCACTCGGAG
TCCAGGGCCA GACAGTGTGG CCTTGACTCG AGAGGCCTCT TGGTCCGGAG CCCTGTTTCC
AAGAGTGCAG CAGCCCCTAC TGTGACCTCT GTGAGAGGAA CCTCGGCGCA CTTTGGGATT
CAGCTCAGAG GTGGCACCAG ATTGCCTGAC AGGCTTAGCT GGCCGTGTGG CCCTGGGAGT
GCTGGGTGGC AGCAAGAGTT TGCAGCCATG GATAGTTCTG AGACCCTGGA CGCCAGCTGG
GAGGCAGCCT GCAGCGATGG AGCAAGGCGT GTCCGGGCAG CAGGCTCTCT GCCATCAGCA
GAGTTGAGTA GCAACAGCTG CAGCCCTGGC TGTGGCCCTG AGGTCCCCCC AACCCCTCCT
GGCTCTCACA GTGCCTTTAC CTCAAGCTTT AGCTTTATTC GGCTCTCGCT TGGCTCTGCC
GGGGAACGTG GAGAAGCAGA AGGCTGCCCA CCATCCAGAG AGGCTGAGTC CCATTGCCAG
AGCCCCCAGG AGATGGGAGC CAAAGCTGCC AGCTTGGACG GGCCTCACGA GGACCCGCGA
TGTCTCTCTC GGCCCTTCAG TCTCTTGGCT ACACGGGTCT CTGCAGACTT GGCCCAGGCC
GCAAGGAACA GCTCCAGGCC AGAGCGTGAC ATGCATTCTT TACCAGACAT GGACCCTGGC
TCCTCCAGTT CTCTGGATCC CTCACTGGCT GGCTGTGGTG GTGATGGGAG CAGCGGCTCA
GGGGATGCCC ACTCTTGGGA CACCCTGCTC AGGAAATGGG AGCCAGTGCT GCGGGACTGC
CTGCTGAGAA ACCGGAGGCA GATGGAGGTA ATATCCTTAA GATTAAAACT TCAGAAACTT
CAGGAAGATG CAGTTGAGAA TGATGATTAT GATAAAGCTG AGACGTTACA ACAAAGATTA
GAAGACCTGG AACAAGAGAA AATCAGCCTG CACTTTCAAC TTCCTTCAAG GCAGCCAGCT
CTTAGCAGTT TCCTGGGTCA CCTGGCAGCA CAAGTCCAGG CTGCCTTGCG CCGTGGGGCC
ACTCAGCAGG CCAGCGGAGA TGACACCCAC ACCCCACTGA GAATGGAGCC GAGGCTGTTG
GAACCCACTG CTCAGGACAG CTTGCACGTG TCCATCACGA GACGAGACTG GCTTCTTCAG
GAAAAGCAGC AGCTACAGAA AGAAATCGAA GCTCTCCAAG CAAGGATGTT TGTGCTGGAA
GCCAAAGATC AACAGCTGAG AAGGGAAATA GAGGAGCAAG AGCAGCAACT CCAGTGGCAG
GGCTGCGACC TGACCCCACT GGTGGGCCAG CTGTCCCTGG GTCAGCTGCA GGAGGTCAGC
AAGGCCTTGC AGGACACCCT GGCCTCAGCC GGTCAGATTC CCTTCCATGC AGAGCCACCG
GAAACCATAA GGAGAAACAA GTGTGAAGGA AAATACTATG AAGTACATGG AAACACTTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu24840
Clone ID Related Accession (Same CDS sequence) NM_001164546 , NM_001164547
Accession Version NM_001164547.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1680bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product disrupted in schizophrenia 1 protein isoform i
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from FJ804184.1 and BC142622.1. Transcript Variant: This variant (j) lacks three internal exons and two 3' exons but has an alternate 3' segment, as compared to variant L. Variants i and j encode the same isoform (i), which is much shorter and has a distinct C-terminus, as compared to isoform L. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: FJ804184.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1968540, SAMEA2142348 [ECO:0000350] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
ATGCCAGGCG GGGGTCCTCA GGGCGCCCCA GCCGCCGCCG GCGGCGGCGG CGTGAGCCAC 
CGCGCAGGCA GCCGGGATTG CTTACCACCT GCAGCGTGCT TTCGGAGGCG GCGGCTGGCA
CGGAGGCCGG GCTACATGAG AAGCTCGACA GGGCCTGGGA TCGGGTTCCT TTCCCCAGCA
GTGGGCACAC TGTTCCGGTT CCCAGGAGGG GTGTCTGGCG AGGAGTCCCA CCACTCGGAG
TCCAGGGCCA GACAGTGTGG CCTTGACTCG AGAGGCCTCT TGGTCCGGAG CCCTGTTTCC
AAGAGTGCAG CAGCCCCTAC TGTGACCTCT GTGAGAGGAA CCTCGGCGCA CTTTGGGATT
CAGCTCAGAG GTGGCACCAG ATTGCCTGAC AGGCTTAGCT GGCCGTGTGG CCCTGGGAGT
GCTGGGTGGC AGCAAGAGTT TGCAGCCATG GATAGTTCTG AGACCCTGGA CGCCAGCTGG
GAGGCAGCCT GCAGCGATGG AGCAAGGCGT GTCCGGGCAG CAGGCTCTCT GCCATCAGCA
GAGTTGAGTA GCAACAGCTG CAGCCCTGGC TGTGGCCCTG AGGTCCCCCC AACCCCTCCT
GGCTCTCACA GTGCCTTTAC CTCAAGCTTT AGCTTTATTC GGCTCTCGCT TGGCTCTGCC
GGGGAACGTG GAGAAGCAGA AGGCTGCCCA CCATCCAGAG AGGCTGAGTC CCATTGCCAG
AGCCCCCAGG AGATGGGAGC CAAAGCTGCC AGCTTGGACG GGCCTCACGA GGACCCGCGA
TGTCTCTCTC GGCCCTTCAG TCTCTTGGCT ACACGGGTCT CTGCAGACTT GGCCCAGGCC
GCAAGGAACA GCTCCAGGCC AGAGCGTGAC ATGCATTCTT TACCAGACAT GGACCCTGGC
TCCTCCAGTT CTCTGGATCC CTCACTGGCT GGCTGTGGTG GTGATGGGAG CAGCGGCTCA
GGGGATGCCC ACTCTTGGGA CACCCTGCTC AGGAAATGGG AGCCAGTGCT GCGGGACTGC
CTGCTGAGAA ACCGGAGGCA GATGGAGGTA ATATCCTTAA GATTAAAACT TCAGAAACTT
CAGGAAGATG CAGTTGAGAA TGATGATTAT GATAAAGCTG AGACGTTACA ACAAAGATTA
GAAGACCTGG AACAAGAGAA AATCAGCCTG CACTTTCAAC TTCCTTCAAG GCAGCCAGCT
CTTAGCAGTT TCCTGGGTCA CCTGGCAGCA CAAGTCCAGG CTGCCTTGCG CCGTGGGGCC
ACTCAGCAGG CCAGCGGAGA TGACACCCAC ACCCCACTGA GAATGGAGCC GAGGCTGTTG
GAACCCACTG CTCAGGACAG CTTGCACGTG TCCATCACGA GACGAGACTG GCTTCTTCAG
GAAAAGCAGC AGCTACAGAA AGAAATCGAA GCTCTCCAAG CAAGGATGTT TGTGCTGGAA
GCCAAAGATC AACAGCTGAG AAGGGAAATA GAGGAGCAAG AGCAGCAACT CCAGTGGCAG
GGCTGCGACC TGACCCCACT GGTGGGCCAG CTGTCCCTGG GTCAGCTGCA GGAGGTCAGC
AAGGCCTTGC AGGACACCCT GGCCTCAGCC GGTCAGATTC CCTTCCATGC AGAGCCACCG
GAAACCATAA GGAGAAACAA GTGTGAAGGA AAATACTATG AAGTACATGG AAACACTTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001158019.1
CDS54..1733
Misc Feature(1)54..929(+)
Misc Feature(2)1074..1517(+)
Exon (1)1..120
Gene:DISC1
Gene Synonym:
Exon (2)121..1100
Gene:DISC1
Gene Synonym:
Exon (3)1101..1170
Gene:DISC1
Gene Synonym:
Exon (4)1171..1321
Gene:DISC1
Gene Synonym:
Exon (5)1322..1451
Gene:DISC1
Gene Synonym:
Exon (6)1452..1687
Gene:DISC1
Gene Synonym:
Exon (7)1688..1748
Gene:DISC1
Gene Synonym:
Exon (8)1749..2618
Gene:DISC1
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001164547
Organism Homo sapiens (human)
Definition Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant j, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001164547

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
ATGCCAGGCG GGGGTCCTCA GGGCGCCCCA GCCGCCGCCG GCGGCGGCGG CGTGAGCCAC 
CGCGCAGGCA GCCGGGATTG CTTACCACCT GCAGCGTGCT TTCGGAGGCG GCGGCTGGCA
CGGAGGCCGG GCTACATGAG AAGCTCGACA GGGCCTGGGA TCGGGTTCCT TTCCCCAGCA
GTGGGCACAC TGTTCCGGTT CCCAGGAGGG GTGTCTGGCG AGGAGTCCCA CCACTCGGAG
TCCAGGGCCA GACAGTGTGG CCTTGACTCG AGAGGCCTCT TGGTCCGGAG CCCTGTTTCC
AAGAGTGCAG CAGCCCCTAC TGTGACCTCT GTGAGAGGAA CCTCGGCGCA CTTTGGGATT
CAGCTCAGAG GTGGCACCAG ATTGCCTGAC AGGCTTAGCT GGCCGTGTGG CCCTGGGAGT
GCTGGGTGGC AGCAAGAGTT TGCAGCCATG GATAGTTCTG AGACCCTGGA CGCCAGCTGG
GAGGCAGCCT GCAGCGATGG AGCAAGGCGT GTCCGGGCAG CAGGCTCTCT GCCATCAGCA
GAGTTGAGTA GCAACAGCTG CAGCCCTGGC TGTGGCCCTG AGGTCCCCCC AACCCCTCCT
GGCTCTCACA GTGCCTTTAC CTCAAGCTTT AGCTTTATTC GGCTCTCGCT TGGCTCTGCC
GGGGAACGTG GAGAAGCAGA AGGCTGCCCA CCATCCAGAG AGGCTGAGTC CCATTGCCAG
AGCCCCCAGG AGATGGGAGC CAAAGCTGCC AGCTTGGACG GGCCTCACGA GGACCCGCGA
TGTCTCTCTC GGCCCTTCAG TCTCTTGGCT ACACGGGTCT CTGCAGACTT GGCCCAGGCC
GCAAGGAACA GCTCCAGGCC AGAGCGTGAC ATGCATTCTT TACCAGACAT GGACCCTGGC
TCCTCCAGTT CTCTGGATCC CTCACTGGCT GGCTGTGGTG GTGATGGGAG CAGCGGCTCA
GGGGATGCCC ACTCTTGGGA CACCCTGCTC AGGAAATGGG AGCCAGTGCT GCGGGACTGC
CTGCTGAGAA ACCGGAGGCA GATGGAGGTA ATATCCTTAA GATTAAAACT TCAGAAACTT
CAGGAAGATG CAGTTGAGAA TGATGATTAT GATAAAGCTG AGACGTTACA ACAAAGATTA
GAAGACCTGG AACAAGAGAA AATCAGCCTG CACTTTCAAC TTCCTTCAAG GCAGCCAGCT
CTTAGCAGTT TCCTGGGTCA CCTGGCAGCA CAAGTCCAGG CTGCCTTGCG CCGTGGGGCC
ACTCAGCAGG CCAGCGGAGA TGACACCCAC ACCCCACTGA GAATGGAGCC GAGGCTGTTG
GAACCCACTG CTCAGGACAG CTTGCACGTG TCCATCACGA GACGAGACTG GCTTCTTCAG
GAAAAGCAGC AGCTACAGAA AGAAATCGAA GCTCTCCAAG CAAGGATGTT TGTGCTGGAA
GCCAAAGATC AACAGCTGAG AAGGGAAATA GAGGAGCAAG AGCAGCAACT CCAGTGGCAG
GGCTGCGACC TGACCCCACT GGTGGGCCAG CTGTCCCTGG GTCAGCTGCA GGAGGTCAGC
AAGGCCTTGC AGGACACCCT GGCCTCAGCC GGTCAGATTC CCTTCCATGC AGAGCCACCG
GAAACCATAA GGAGAAACAA GTGTGAAGGA AAATACTATG AAGTACATGG AAACACTTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu25023
Clone ID Related Accession (Same CDS sequence) NM_001164548
Accession Version NM_001164548.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1656bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product disrupted in schizophrenia 1 protein isoform k
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from FJ804202.1. Transcript Variant: This variant (k) lacks two internal exons and multiple 3' exons but has an alternate 3' segment, as compared to variant L. The resulting isoform (k, also known as isoform 32) is much shorter and has a distinct C-terminus, as compared to isoform L. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: FJ804202.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
ATGCCAGGCG GGGGTCCTCA GGGCGCCCCA GCCGCCGCCG GCGGCGGCGG CGTGAGCCAC 
CGCGCAGGCA GCCGGGATTG CTTACCACCT GCAGCGTGCT TTCGGAGGCG GCGGCTGGCA
CGGAGGCCGG GCTACATGAG AAGCTCGACA GGGCCTGGGA TCGGGTTCCT TTCCCCAGCA
GTGGGCACAC TGTTCCGGTT CCCAGGAGGG GTGTCTGGCG AGGAGTCCCA CCACTCGGAG
TCCAGGGCCA GACAGTGTGG CCTTGACTCG AGAGGCCTCT TGGTCCGGAG CCCTGTTTCC
AAGAGTGCAG CAGCCCCTAC TGTGACCTCT GTGAGAGGAA CCTCGGCGCA CTTTGGGATT
CAGCTCAGAG GTGGCACCAG ATTGCCTGAC AGGCTTAGCT GGCCGTGTGG CCCTGGGAGT
GCTGGGTGGC AGCAAGAGTT TGCAGCCATG GATAGTTCTG AGACCCTGGA CGCCAGCTGG
GAGGCAGCCT GCAGCGATGG AGCAAGGCGT GTCCGGGCAG CAGGCTCTCT GCCATCAGCA
GAGTTGAGTA GCAACAGCTG CAGCCCTGGC TGTGGCCCTG AGGTCCCCCC AACCCCTCCT
GGCTCTCACA GTGCCTTTAC CTCAAGCTTT AGCTTTATTC GGCTCTCGCT TGGCTCTGCC
GGGGAACGTG GAGAAGCAGA AGGCTGCCCA CCATCCAGAG AGGCTGAGTC CCATTGCCAG
AGCCCCCAGG AGATGGGAGC CAAAGCTGCC AGCTTGGACG GGCCTCACGA GGACCCGCGA
TGTCTCTCTC GGCCCTTCAG TCTCTTGGCT ACACGGGTCT CTGCAGACTT GGCCCAGGCC
GCAAGGAACA GCTCCAGGCC AGAGCGTGAC ATGCATTCTT TACCAGACAT GGACCCTGGC
TCCTCCAGTT CTCTGGATCC CTCACTGGCT GGCTGTGGTG GTGATGGGAG CAGCGGCTCA
GGGGATGCCC ACTCTTGGGA CACCCTGCTC AGGAAATGGG AGCCAGTGCT GCGGGACTGC
CTGCTGAGAA ACCGGAGGCA GATGGAGGTA ATATCCTTAA GATTAAAACT TCAGAAACTT
CAGGAAGATG CAGTTGAGAA TGATGATTAT GATAAAGCTG AGACGTTACA ACAAAGATTA
GAAGACCTGG AACAAGAGAA AATCAGCCTG CACTTTCAAC TTCCTTCAAG GCAGCCAGCT
CTTAGCAGTT TCCTGGGTCA CCTGGCAGCA CAAGTCCAGG CTGCCTTGCG CCGTGGGGCC
ACTCAGCAGG CCAGCGGAGA TGACACCCAC ACCCCACTGA GAATGGAGCC GAGGCTGTTG
GAACCCACTG CTCAGGACAG CTTGCACGTG TCCATCACGA GACGAGACTG GCTTCTTCAG
GAAAAGCAGC AGCTACAGAA AGAAATCGAA GCTCTCCAAG CAAGGATGTT TGTGCTGGAA
GCCAAAGATC AACAGCTGAG AAGGGAAATA GAGGAGCAAG AGCAGCAACT CCAGTGGCAG
GGCTGCGACC TGACCCCACT GGTGGGCCAG CTGTCCCTGG GTCAGCTGCA GGAGGTCAGC
AAGGCCTTGC AGGACACCCT GGCCTCAGCC GGTCAGATTC CCTTCCATGC AGAGCCACCG
GAAACCATAA GGAGGAAACC ATTTCTGGAC GGCTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001158020.1
CDS54..1709
Misc Feature(1)54..929(+)
Misc Feature(2)1074..1517(+)
Exon (1)1..120
Gene:DISC1
Gene Synonym:
Exon (2)121..1100
Gene:DISC1
Gene Synonym:
Exon (3)1101..1170
Gene:DISC1
Gene Synonym:
Exon (4)1171..1321
Gene:DISC1
Gene Synonym:
Exon (5)1322..1451
Gene:DISC1
Gene Synonym:
Exon (6)1452..1687
Gene:DISC1
Gene Synonym:
Exon (7)1688..2603
Gene:DISC1
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001164548
Organism Homo sapiens (human)
Definition Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant k, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001164548

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
ATGCCAGGCG GGGGTCCTCA GGGCGCCCCA GCCGCCGCCG GCGGCGGCGG CGTGAGCCAC 
CGCGCAGGCA GCCGGGATTG CTTACCACCT GCAGCGTGCT TTCGGAGGCG GCGGCTGGCA
CGGAGGCCGG GCTACATGAG AAGCTCGACA GGGCCTGGGA TCGGGTTCCT TTCCCCAGCA
GTGGGCACAC TGTTCCGGTT CCCAGGAGGG GTGTCTGGCG AGGAGTCCCA CCACTCGGAG
TCCAGGGCCA GACAGTGTGG CCTTGACTCG AGAGGCCTCT TGGTCCGGAG CCCTGTTTCC
AAGAGTGCAG CAGCCCCTAC TGTGACCTCT GTGAGAGGAA CCTCGGCGCA CTTTGGGATT
CAGCTCAGAG GTGGCACCAG ATTGCCTGAC AGGCTTAGCT GGCCGTGTGG CCCTGGGAGT
GCTGGGTGGC AGCAAGAGTT TGCAGCCATG GATAGTTCTG AGACCCTGGA CGCCAGCTGG
GAGGCAGCCT GCAGCGATGG AGCAAGGCGT GTCCGGGCAG CAGGCTCTCT GCCATCAGCA
GAGTTGAGTA GCAACAGCTG CAGCCCTGGC TGTGGCCCTG AGGTCCCCCC AACCCCTCCT
GGCTCTCACA GTGCCTTTAC CTCAAGCTTT AGCTTTATTC GGCTCTCGCT TGGCTCTGCC
GGGGAACGTG GAGAAGCAGA AGGCTGCCCA CCATCCAGAG AGGCTGAGTC CCATTGCCAG
AGCCCCCAGG AGATGGGAGC CAAAGCTGCC AGCTTGGACG GGCCTCACGA GGACCCGCGA
TGTCTCTCTC GGCCCTTCAG TCTCTTGGCT ACACGGGTCT CTGCAGACTT GGCCCAGGCC
GCAAGGAACA GCTCCAGGCC AGAGCGTGAC ATGCATTCTT TACCAGACAT GGACCCTGGC
TCCTCCAGTT CTCTGGATCC CTCACTGGCT GGCTGTGGTG GTGATGGGAG CAGCGGCTCA
GGGGATGCCC ACTCTTGGGA CACCCTGCTC AGGAAATGGG AGCCAGTGCT GCGGGACTGC
CTGCTGAGAA ACCGGAGGCA GATGGAGGTA ATATCCTTAA GATTAAAACT TCAGAAACTT
CAGGAAGATG CAGTTGAGAA TGATGATTAT GATAAAGCTG AGACGTTACA ACAAAGATTA
GAAGACCTGG AACAAGAGAA AATCAGCCTG CACTTTCAAC TTCCTTCAAG GCAGCCAGCT
CTTAGCAGTT TCCTGGGTCA CCTGGCAGCA CAAGTCCAGG CTGCCTTGCG CCGTGGGGCC
ACTCAGCAGG CCAGCGGAGA TGACACCCAC ACCCCACTGA GAATGGAGCC GAGGCTGTTG
GAACCCACTG CTCAGGACAG CTTGCACGTG TCCATCACGA GACGAGACTG GCTTCTTCAG
GAAAAGCAGC AGCTACAGAA AGAAATCGAA GCTCTCCAAG CAAGGATGTT TGTGCTGGAA
GCCAAAGATC AACAGCTGAG AAGGGAAATA GAGGAGCAAG AGCAGCAACT CCAGTGGCAG
GGCTGCGACC TGACCCCACT GGTGGGCCAG CTGTCCCTGG GTCAGCTGCA GGAGGTCAGC
AAGGCCTTGC AGGACACCCT GGCCTCAGCC GGTCAGATTC CCTTCCATGC AGAGCCACCG
GAAACCATAA GGAGGAAACC ATTTCTGGAC GGCTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu24871
Clone ID Related Accession (Same CDS sequence) NM_001164549
Accession Version NM_001164549.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1644bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product disrupted in schizophrenia 1 protein isoform l
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from FJ804207.1. Transcript Variant: This variant (l) lacks multiple 3' exons but has an alternate 3' segment, as compared to variant L. The resulting isoform (l, also known as isoform 37) is much shorter and has a distinct C-terminus, as compared to isoform L. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: FJ804207.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2142348 [ECO:0000348] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
ATGCCAGGCG GGGGTCCTCA GGGCGCCCCA GCCGCCGCCG GCGGCGGCGG CGTGAGCCAC 
CGCGCAGGCA GCCGGGATTG CTTACCACCT GCAGCGTGCT TTCGGAGGCG GCGGCTGGCA
CGGAGGCCGG GCTACATGAG AAGCTCGACA GGGCCTGGGA TCGGGTTCCT TTCCCCAGCA
GTGGGCACAC TGTTCCGGTT CCCAGGAGGG GTGTCTGGCG AGGAGTCCCA CCACTCGGAG
TCCAGGGCCA GACAGTGTGG CCTTGACTCG AGAGGCCTCT TGGTCCGGAG CCCTGTTTCC
AAGAGTGCAG CAGCCCCTAC TGTGACCTCT GTGAGAGGAA CCTCGGCGCA CTTTGGGATT
CAGCTCAGAG GTGGCACCAG ATTGCCTGAC AGGCTTAGCT GGCCGTGTGG CCCTGGGAGT
GCTGGGTGGC AGCAAGAGTT TGCAGCCATG GATAGTTCTG AGACCCTGGA CGCCAGCTGG
GAGGCAGCCT GCAGCGATGG AGCAAGGCGT GTCCGGGCAG CAGGCTCTCT GCCATCAGCA
GAGTTGAGTA GCAACAGCTG CAGCCCTGGC TGTGGCCCTG AGGTCCCCCC AACCCCTCCT
GGCTCTCACA GTGCCTTTAC CTCAAGCTTT AGCTTTATTC GGCTCTCGCT TGGCTCTGCC
GGGGAACGTG GAGAAGCAGA AGGCTGCCCA CCATCCAGAG AGGCTGAGTC CCATTGCCAG
AGCCCCCAGG AGATGGGAGC CAAAGCTGCC AGCTTGGACG GGCCTCACGA GGACCCGCGA
TGTCTCTCTC GGCCCTTCAG TCTCTTGGCT ACACGGGTCT CTGCAGACTT GGCCCAGGCC
GCAAGGAACA GCTCCAGGCC AGAGCGTGAC ATGCATTCTT TACCAGACAT GGACCCTGGC
TCCTCCAGTT CTCTGGATCC CTCACTGGCT GGCTGTGGTG GTGATGGGAG CAGCGGCTCA
GGGGATGCCC ACTCTTGGGA CACCCTGCTC AGGAAATGGG AGCCAGTGCT GCGGGACTGC
CTGCTGAGAA ACCGGAGGCA GATGGAGGTA ATATCCTTAA GATTAAAACT TCAGAAACTT
CAGGAAGATG CAGTTGAGAA TGATGATTAT GATAAAGCTG AGACGTTACA ACAAAGATTA
GAAGACCTGG AACAAGAGAA AATCAGCCTG CACTTTCAAC TTCCTTCAAG GCAGCCAGCT
CTTAGCAGTT TCCTGGGTCA CCTGGCAGCA CAAGTCCAGG CTGCCTTGCG CCGTGGGGCC
ACTCAGCAGG CCAGCGGAGA TGACACCCAC ACCCCACTGA GAATGGAGCC GAGGCTGTTG
GAACCCACTG CTCAGGACAG CTTGCACGTG TCCATCACGA GACGAGACTG GCTTCTTCAG
GAAAAGCAGC AGCTACAGAA AGAAATCGAA GCTCTCCAAG CAAGGATGTT TGTGCTGGAA
GCCAAAGATC AACAGCTGAG AAGGGAAATA GAGGAGCAAG AGCAGCAACT CCAGTGGCAG
GGCTGCGACC TGACCCCACT GGTGGGCCAG CTGTCCCTGG GTCAGCTGCA GGAGGTCAGC
AAGGCCTTGC AGGACACCCT GGCCTCAGCC GGTCAGATTC CCTTCCATGC AGAGCCACCG
GAAACCATAA GGAGGTACTG CTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001158021.1
CDS54..1697
Misc Feature(1)54..929(+)
Misc Feature(2)1074..1517(+)
Exon (1)1..120
Gene:DISC1
Gene Synonym:
Exon (2)121..1100
Gene:DISC1
Gene Synonym:
Exon (3)1101..1170
Gene:DISC1
Gene Synonym:
Exon (4)1171..1321
Gene:DISC1
Gene Synonym:
Exon (5)1322..1451
Gene:DISC1
Gene Synonym:
Exon (6)1452..2279
Gene:DISC1
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001164549
Organism Homo sapiens (human)
Definition Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant l, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001164549

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
ATGCCAGGCG GGGGTCCTCA GGGCGCCCCA GCCGCCGCCG GCGGCGGCGG CGTGAGCCAC 
CGCGCAGGCA GCCGGGATTG CTTACCACCT GCAGCGTGCT TTCGGAGGCG GCGGCTGGCA
CGGAGGCCGG GCTACATGAG AAGCTCGACA GGGCCTGGGA TCGGGTTCCT TTCCCCAGCA
GTGGGCACAC TGTTCCGGTT CCCAGGAGGG GTGTCTGGCG AGGAGTCCCA CCACTCGGAG
TCCAGGGCCA GACAGTGTGG CCTTGACTCG AGAGGCCTCT TGGTCCGGAG CCCTGTTTCC
AAGAGTGCAG CAGCCCCTAC TGTGACCTCT GTGAGAGGAA CCTCGGCGCA CTTTGGGATT
CAGCTCAGAG GTGGCACCAG ATTGCCTGAC AGGCTTAGCT GGCCGTGTGG CCCTGGGAGT
GCTGGGTGGC AGCAAGAGTT TGCAGCCATG GATAGTTCTG AGACCCTGGA CGCCAGCTGG
GAGGCAGCCT GCAGCGATGG AGCAAGGCGT GTCCGGGCAG CAGGCTCTCT GCCATCAGCA
GAGTTGAGTA GCAACAGCTG CAGCCCTGGC TGTGGCCCTG AGGTCCCCCC AACCCCTCCT
GGCTCTCACA GTGCCTTTAC CTCAAGCTTT AGCTTTATTC GGCTCTCGCT TGGCTCTGCC
GGGGAACGTG GAGAAGCAGA AGGCTGCCCA CCATCCAGAG AGGCTGAGTC CCATTGCCAG
AGCCCCCAGG AGATGGGAGC CAAAGCTGCC AGCTTGGACG GGCCTCACGA GGACCCGCGA
TGTCTCTCTC GGCCCTTCAG TCTCTTGGCT ACACGGGTCT CTGCAGACTT GGCCCAGGCC
GCAAGGAACA GCTCCAGGCC AGAGCGTGAC ATGCATTCTT TACCAGACAT GGACCCTGGC
TCCTCCAGTT CTCTGGATCC CTCACTGGCT GGCTGTGGTG GTGATGGGAG CAGCGGCTCA
GGGGATGCCC ACTCTTGGGA CACCCTGCTC AGGAAATGGG AGCCAGTGCT GCGGGACTGC
CTGCTGAGAA ACCGGAGGCA GATGGAGGTA ATATCCTTAA GATTAAAACT TCAGAAACTT
CAGGAAGATG CAGTTGAGAA TGATGATTAT GATAAAGCTG AGACGTTACA ACAAAGATTA
GAAGACCTGG AACAAGAGAA AATCAGCCTG CACTTTCAAC TTCCTTCAAG GCAGCCAGCT
CTTAGCAGTT TCCTGGGTCA CCTGGCAGCA CAAGTCCAGG CTGCCTTGCG CCGTGGGGCC
ACTCAGCAGG CCAGCGGAGA TGACACCCAC ACCCCACTGA GAATGGAGCC GAGGCTGTTG
GAACCCACTG CTCAGGACAG CTTGCACGTG TCCATCACGA GACGAGACTG GCTTCTTCAG
GAAAAGCAGC AGCTACAGAA AGAAATCGAA GCTCTCCAAG CAAGGATGTT TGTGCTGGAA
GCCAAAGATC AACAGCTGAG AAGGGAAATA GAGGAGCAAG AGCAGCAACT CCAGTGGCAG
GGCTGCGACC TGACCCCACT GGTGGGCCAG CTGTCCCTGG GTCAGCTGCA GGAGGTCAGC
AAGGCCTTGC AGGACACCCT GGCCTCAGCC GGTCAGATTC CCTTCCATGC AGAGCCACCG
GAAACCATAA GGAGGTACTG CTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu24884
Clone ID Related Accession (Same CDS sequence) NM_001164550
Accession Version NM_001164550.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1290bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product disrupted in schizophrenia 1 protein isoform m
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from FJ804215.1. Transcript Variant: This variant (m) lacks multiple 3' exons but has two alternate 3' exons, as compared to variant L. The resulting isoform (m, also known as isoform 45) is much shorter and has a distinct C-terminus, as compared to isoform L. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: FJ804215.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGCCAGGCG GGGGTCCTCA GGGCGCCCCA GCCGCCGCCG GCGGCGGCGG CGTGAGCCAC 
CGCGCAGGCA GCCGGGATTG CTTACCACCT GCAGCGTGCT TTCGGAGGCG GCGGCTGGCA
CGGAGGCCGG GCTACATGAG AAGCTCGACA GGGCCTGGGA TCGGGTTCCT TTCCCCAGCA
GTGGGCACAC TGTTCCGGTT CCCAGGAGGG GTGTCTGGCG AGGAGTCCCA CCACTCGGAG
TCCAGGGCCA GACAGTGTGG CCTTGACTCG AGAGGCCTCT TGGTCCGGAG CCCTGTTTCC
AAGAGTGCAG CAGCCCCTAC TGTGACCTCT GTGAGAGGAA CCTCGGCGCA CTTTGGGATT
CAGCTCAGAG GTGGCACCAG ATTGCCTGAC AGGCTTAGCT GGCCGTGTGG CCCTGGGAGT
GCTGGGTGGC AGCAAGAGTT TGCAGCCATG GATAGTTCTG AGACCCTGGA CGCCAGCTGG
GAGGCAGCCT GCAGCGATGG AGCAAGGCGT GTCCGGGCAG CAGGCTCTCT GCCATCAGCA
GAGTTGAGTA GCAACAGCTG CAGCCCTGGC TGTGGCCCTG AGGTCCCCCC AACCCCTCCT
GGCTCTCACA GTGCCTTTAC CTCAAGCTTT AGCTTTATTC GGCTCTCGCT TGGCTCTGCC
GGGGAACGTG GAGAAGCAGA AGGCTGCCCA CCATCCAGAG AGGCTGAGTC CCATTGCCAG
AGCCCCCAGG AGATGGGAGC CAAAGCTGCC AGCTTGGACG GGCCTCACGA GGACCCGCGA
TGTCTCTCTC GGCCCTTCAG TCTCTTGGCT ACACGGGTCT CTGCAGACTT GGCCCAGGCC
GCAAGGAACA GCTCCAGGCC AGAGCGTGAC ATGCATTCTT TACCAGACAT GGACCCTGGC
TCCTCCAGTT CTCTGGATCC CTCACTGGCT GGCTGTGGTG GTGATGGGAG CAGCGGCTCA
GGGGATGCCC ACTCTTGGGA CACCCTGCTC AGGAAATGGG AGCCAGTGCT GCGGGACTGC
CTGCTGAGAA ACCGGAGGCA GATGGAGGTA ATATCCTTAA GATTAAAACT TCAGAAACTT
CAGGAAGATG CAGTTGAGAA TGATGATTAT GATAAAGGAA GTCACTGGAA GGGTTACATT
TTCATTTGGG GTGAACAGCA ACTGTGGATA CGGATCATGA AAATTGACAA TGGAAAATGG
GCATGCCATT CTGGAACTTT TCCCAGCTTT TTTCCAGAGC CAGCTGGAAC CAATTGCTTT
GGATCCACCA TGGAAGCCTC GACATCCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001158022.1
CDS54..1343
Misc Feature(1)54..929(+)
Exon (1)1..120
Gene:DISC1
Gene Synonym:
Exon (2)121..1100
Gene:DISC1
Gene Synonym:
Exon (3)1101..1170
Gene:DISC1
Gene Synonym:
Exon (4)1171..1296
Gene:DISC1
Gene Synonym:
Exon (5)1297..2832
Gene:DISC1
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001164550
Organism Homo sapiens (human)
Definition Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant m, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001164550

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGCCAGGCG GGGGTCCTCA GGGCGCCCCA GCCGCCGCCG GCGGCGGCGG CGTGAGCCAC 
CGCGCAGGCA GCCGGGATTG CTTACCACCT GCAGCGTGCT TTCGGAGGCG GCGGCTGGCA
CGGAGGCCGG GCTACATGAG AAGCTCGACA GGGCCTGGGA TCGGGTTCCT TTCCCCAGCA
GTGGGCACAC TGTTCCGGTT CCCAGGAGGG GTGTCTGGCG AGGAGTCCCA CCACTCGGAG
TCCAGGGCCA GACAGTGTGG CCTTGACTCG AGAGGCCTCT TGGTCCGGAG CCCTGTTTCC
AAGAGTGCAG CAGCCCCTAC TGTGACCTCT GTGAGAGGAA CCTCGGCGCA CTTTGGGATT
CAGCTCAGAG GTGGCACCAG ATTGCCTGAC AGGCTTAGCT GGCCGTGTGG CCCTGGGAGT
GCTGGGTGGC AGCAAGAGTT TGCAGCCATG GATAGTTCTG AGACCCTGGA CGCCAGCTGG
GAGGCAGCCT GCAGCGATGG AGCAAGGCGT GTCCGGGCAG CAGGCTCTCT GCCATCAGCA
GAGTTGAGTA GCAACAGCTG CAGCCCTGGC TGTGGCCCTG AGGTCCCCCC AACCCCTCCT
GGCTCTCACA GTGCCTTTAC CTCAAGCTTT AGCTTTATTC GGCTCTCGCT TGGCTCTGCC
GGGGAACGTG GAGAAGCAGA AGGCTGCCCA CCATCCAGAG AGGCTGAGTC CCATTGCCAG
AGCCCCCAGG AGATGGGAGC CAAAGCTGCC AGCTTGGACG GGCCTCACGA GGACCCGCGA
TGTCTCTCTC GGCCCTTCAG TCTCTTGGCT ACACGGGTCT CTGCAGACTT GGCCCAGGCC
GCAAGGAACA GCTCCAGGCC AGAGCGTGAC ATGCATTCTT TACCAGACAT GGACCCTGGC
TCCTCCAGTT CTCTGGATCC CTCACTGGCT GGCTGTGGTG GTGATGGGAG CAGCGGCTCA
GGGGATGCCC ACTCTTGGGA CACCCTGCTC AGGAAATGGG AGCCAGTGCT GCGGGACTGC
CTGCTGAGAA ACCGGAGGCA GATGGAGGTA ATATCCTTAA GATTAAAACT TCAGAAACTT
CAGGAAGATG CAGTTGAGAA TGATGATTAT GATAAAGGAA GTCACTGGAA GGGTTACATT
TTCATTTGGG GTGAACAGCA ACTGTGGATA CGGATCATGA AAATTGACAA TGGAAAATGG
GCATGCCATT CTGGAACTTT TCCCAGCTTT TTTCCAGAGC CAGCTGGAAC CAATTGCTTT
GGATCCACCA TGGAAGCCTC GACATCCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu24838
Clone ID Related Accession (Same CDS sequence) NM_001164551
Accession Version NM_001164551.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1272bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product disrupted in schizophrenia 1 protein isoform n
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from FJ804211.1. Transcript Variant: This variant (n) lacks multiple 3' exons but has an alternate 3' segment, as compared to variant L. The resulting isoform (n, also known as isoform 41) is much shorter and has a truncated C-terminus, as compared to isoform L. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: FJ804211.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2142348 [ECO:0000348] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGCCAGGCG GGGGTCCTCA GGGCGCCCCA GCCGCCGCCG GCGGCGGCGG CGTGAGCCAC 
CGCGCAGGCA GCCGGGATTG CTTACCACCT GCAGCGTGCT TTCGGAGGCG GCGGCTGGCA
CGGAGGCCGG GCTACATGAG AAGCTCGACA GGGCCTGGGA TCGGGTTCCT TTCCCCAGCA
GTGGGCACAC TGTTCCGGTT CCCAGGAGGG GTGTCTGGCG AGGAGTCCCA CCACTCGGAG
TCCAGGGCCA GACAGTGTGG CCTTGACTCG AGAGGCCTCT TGGTCCGGAG CCCTGTTTCC
AAGAGTGCAG CAGCCCCTAC TGTGACCTCT GTGAGAGGAA CCTCGGCGCA CTTTGGGATT
CAGCTCAGAG GTGGCACCAG ATTGCCTGAC AGGCTTAGCT GGCCGTGTGG CCCTGGGAGT
GCTGGGTGGC AGCAAGAGTT TGCAGCCATG GATAGTTCTG AGACCCTGGA CGCCAGCTGG
GAGGCAGCCT GCAGCGATGG AGCAAGGCGT GTCCGGGCAG CAGGCTCTCT GCCATCAGCA
GAGTTGAGTA GCAACAGCTG CAGCCCTGGC TGTGGCCCTG AGGTCCCCCC AACCCCTCCT
GGCTCTCACA GTGCCTTTAC CTCAAGCTTT AGCTTTATTC GGCTCTCGCT TGGCTCTGCC
GGGGAACGTG GAGAAGCAGA AGGCTGCCCA CCATCCAGAG AGGCTGAGTC CCATTGCCAG
AGCCCCCAGG AGATGGGAGC CAAAGCTGCC AGCTTGGACG GGCCTCACGA GGACCCGCGA
TGTCTCTCTC GGCCCTTCAG TCTCTTGGCT ACACGGGTCT CTGCAGACTT GGCCCAGGCC
GCAAGGAACA GCTCCAGGCC AGAGCGTGAC ATGCATTCTT TACCAGACAT GGACCCTGGC
TCCTCCAGTT CTCTGGATCC CTCACTGGCT GGCTGTGGTG GTGATGGGAG CAGCGGCTCA
GGGGATGCCC ACTCTTGGGA CACCCTGCTC AGGAAATGGG AGCCAGTGCT GCGGGACTGC
CTGCTGAGAA ACCGGAGGCA GATGGAGGTA ATATCCTTAA GATTAAAACT TCAGAAACTT
CAGGAAGATG CAGTTGAGAA TGATGATTAT GATAAAGCTG AGACGTTACA ACAAAGATTA
GAAGACCTGG AACAAGAGAA AATCAGCCTG CACTTTCAAC TTCCTTCAAG GCAGCCAGCT
CTTAGCAGTT TCCTGGGTCA CCTGGCAGCA CAAGTCCAGG CTGCCTTGCG CCGTGGGGCC
ACTCAGCAGT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001158023.1
CDS54..1325
Misc Feature(1)54..929(+)
Misc Feature(2)1023..>1211(+)
Exon (1)1..120
Gene:DISC1
Gene Synonym:
Exon (2)121..1100
Gene:DISC1
Gene Synonym:
Exon (3)1101..1170
Gene:DISC1
Gene Synonym:
Exon (4)1171..1864
Gene:DISC1
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001164551
Organism Homo sapiens (human)
Definition Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant n, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001164551

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGCCAGGCG GGGGTCCTCA GGGCGCCCCA GCCGCCGCCG GCGGCGGCGG CGTGAGCCAC 
CGCGCAGGCA GCCGGGATTG CTTACCACCT GCAGCGTGCT TTCGGAGGCG GCGGCTGGCA
CGGAGGCCGG GCTACATGAG AAGCTCGACA GGGCCTGGGA TCGGGTTCCT TTCCCCAGCA
GTGGGCACAC TGTTCCGGTT CCCAGGAGGG GTGTCTGGCG AGGAGTCCCA CCACTCGGAG
TCCAGGGCCA GACAGTGTGG CCTTGACTCG AGAGGCCTCT TGGTCCGGAG CCCTGTTTCC
AAGAGTGCAG CAGCCCCTAC TGTGACCTCT GTGAGAGGAA CCTCGGCGCA CTTTGGGATT
CAGCTCAGAG GTGGCACCAG ATTGCCTGAC AGGCTTAGCT GGCCGTGTGG CCCTGGGAGT
GCTGGGTGGC AGCAAGAGTT TGCAGCCATG GATAGTTCTG AGACCCTGGA CGCCAGCTGG
GAGGCAGCCT GCAGCGATGG AGCAAGGCGT GTCCGGGCAG CAGGCTCTCT GCCATCAGCA
GAGTTGAGTA GCAACAGCTG CAGCCCTGGC TGTGGCCCTG AGGTCCCCCC AACCCCTCCT
GGCTCTCACA GTGCCTTTAC CTCAAGCTTT AGCTTTATTC GGCTCTCGCT TGGCTCTGCC
GGGGAACGTG GAGAAGCAGA AGGCTGCCCA CCATCCAGAG AGGCTGAGTC CCATTGCCAG
AGCCCCCAGG AGATGGGAGC CAAAGCTGCC AGCTTGGACG GGCCTCACGA GGACCCGCGA
TGTCTCTCTC GGCCCTTCAG TCTCTTGGCT ACACGGGTCT CTGCAGACTT GGCCCAGGCC
GCAAGGAACA GCTCCAGGCC AGAGCGTGAC ATGCATTCTT TACCAGACAT GGACCCTGGC
TCCTCCAGTT CTCTGGATCC CTCACTGGCT GGCTGTGGTG GTGATGGGAG CAGCGGCTCA
GGGGATGCCC ACTCTTGGGA CACCCTGCTC AGGAAATGGG AGCCAGTGCT GCGGGACTGC
CTGCTGAGAA ACCGGAGGCA GATGGAGGTA ATATCCTTAA GATTAAAACT TCAGAAACTT
CAGGAAGATG CAGTTGAGAA TGATGATTAT GATAAAGCTG AGACGTTACA ACAAAGATTA
GAAGACCTGG AACAAGAGAA AATCAGCCTG CACTTTCAAC TTCCTTCAAG GCAGCCAGCT
CTTAGCAGTT TCCTGGGTCA CCTGGCAGCA CAAGTCCAGG CTGCCTTGCG CCGTGGGGCC
ACTCAGCAGT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu24928
Clone ID Related Accession (Same CDS sequence) NM_001164552
Accession Version NM_001164552.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1164bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product disrupted in schizophrenia 1 protein isoform o
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from FJ804214.1. Transcript Variant: This variant (o) lacks multiple 3' exons but has two alternate 3' exons, as compared to variant L. The resulting isoform (o, also known as isoform 44) is much shorter and has a distinct C-terminus, as compared to isoform L. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: FJ804214.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
ATGCCAGGCG GGGGTCCTCA GGGCGCCCCA GCCGCCGCCG GCGGCGGCGG CGTGAGCCAC 
CGCGCAGGCA GCCGGGATTG CTTACCACCT GCAGCGTGCT TTCGGAGGCG GCGGCTGGCA
CGGAGGCCGG GCTACATGAG AAGCTCGACA GGGCCTGGGA TCGGGTTCCT TTCCCCAGCA
GTGGGCACAC TGTTCCGGTT CCCAGGAGGG GTGTCTGGCG AGGAGTCCCA CCACTCGGAG
TCCAGGGCCA GACAGTGTGG CCTTGACTCG AGAGGCCTCT TGGTCCGGAG CCCTGTTTCC
AAGAGTGCAG CAGCCCCTAC TGTGACCTCT GTGAGAGGAA CCTCGGCGCA CTTTGGGATT
CAGCTCAGAG GTGGCACCAG ATTGCCTGAC AGGCTTAGCT GGCCGTGTGG CCCTGGGAGT
GCTGGGTGGC AGCAAGAGTT TGCAGCCATG GATAGTTCTG AGACCCTGGA CGCCAGCTGG
GAGGCAGCCT GCAGCGATGG AGCAAGGCGT GTCCGGGCAG CAGGCTCTCT GCCATCAGCA
GAGTTGAGTA GCAACAGCTG CAGCCCTGGC TGTGGCCCTG AGGTCCCCCC AACCCCTCCT
GGCTCTCACA GTGCCTTTAC CTCAAGCTTT AGCTTTATTC GGCTCTCGCT TGGCTCTGCC
GGGGAACGTG GAGAAGCAGA AGGCTGCCCA CCATCCAGAG AGGCTGAGTC CCATTGCCAG
AGCCCCCAGG AGATGGGAGC CAAAGCTGCC AGCTTGGACG GGCCTCACGA GGACCCGCGA
TGTCTCTCTC GGCCCTTCAG TCTCTTGGCT ACACGGGTCT CTGCAGACTT GGCCCAGGCC
GCAAGGAACA GCTCCAGGCC AGAGCGTGAC ATGCATTCTT TACCAGACAT GGACCCTGGC
TCCTCCAGTT CTCTGGATCC CTCACTGGCT GGCTGTGGTG GTGATGGGAG CAGCGGCTCA
GGGGATGCCC ACTCTTGGGA CACCCTGCTC AGGAAATGGG AGCCAGTGCT GCGGGACTGC
CTGCTGAGAA ACCGGAGGCA GATGGAGGTA ATATCCTTAA GATTAAAACT TCAGAAACTT
CAGGAAGATG CAGTTGAGAA TGATGATTAT GATAAAGGTT TGTTGGAGGA AGTTGCTACC
AGTCATCTCA CTTTGCATAC CTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001158024.1
CDS54..1217
Exon (1)1..120
Gene:DISC1
Gene Synonym:
Exon (2)121..1100
Gene:DISC1
Gene Synonym:
Exon (3)1101..1170
Gene:DISC1
Gene Synonym:
Exon (4)1171..1247
Gene:DISC1
Gene Synonym:
Exon (5)1248..2783
Gene:DISC1
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001164552
Organism Homo sapiens (human)
Definition Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant o, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001164552

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
ATGCCAGGCG GGGGTCCTCA GGGCGCCCCA GCCGCCGCCG GCGGCGGCGG CGTGAGCCAC 
CGCGCAGGCA GCCGGGATTG CTTACCACCT GCAGCGTGCT TTCGGAGGCG GCGGCTGGCA
CGGAGGCCGG GCTACATGAG AAGCTCGACA GGGCCTGGGA TCGGGTTCCT TTCCCCAGCA
GTGGGCACAC TGTTCCGGTT CCCAGGAGGG GTGTCTGGCG AGGAGTCCCA CCACTCGGAG
TCCAGGGCCA GACAGTGTGG CCTTGACTCG AGAGGCCTCT TGGTCCGGAG CCCTGTTTCC
AAGAGTGCAG CAGCCCCTAC TGTGACCTCT GTGAGAGGAA CCTCGGCGCA CTTTGGGATT
CAGCTCAGAG GTGGCACCAG ATTGCCTGAC AGGCTTAGCT GGCCGTGTGG CCCTGGGAGT
GCTGGGTGGC AGCAAGAGTT TGCAGCCATG GATAGTTCTG AGACCCTGGA CGCCAGCTGG
GAGGCAGCCT GCAGCGATGG AGCAAGGCGT GTCCGGGCAG CAGGCTCTCT GCCATCAGCA
GAGTTGAGTA GCAACAGCTG CAGCCCTGGC TGTGGCCCTG AGGTCCCCCC AACCCCTCCT
GGCTCTCACA GTGCCTTTAC CTCAAGCTTT AGCTTTATTC GGCTCTCGCT TGGCTCTGCC
GGGGAACGTG GAGAAGCAGA AGGCTGCCCA CCATCCAGAG AGGCTGAGTC CCATTGCCAG
AGCCCCCAGG AGATGGGAGC CAAAGCTGCC AGCTTGGACG GGCCTCACGA GGACCCGCGA
TGTCTCTCTC GGCCCTTCAG TCTCTTGGCT ACACGGGTCT CTGCAGACTT GGCCCAGGCC
GCAAGGAACA GCTCCAGGCC AGAGCGTGAC ATGCATTCTT TACCAGACAT GGACCCTGGC
TCCTCCAGTT CTCTGGATCC CTCACTGGCT GGCTGTGGTG GTGATGGGAG CAGCGGCTCA
GGGGATGCCC ACTCTTGGGA CACCCTGCTC AGGAAATGGG AGCCAGTGCT GCGGGACTGC
CTGCTGAGAA ACCGGAGGCA GATGGAGGTA ATATCCTTAA GATTAAAACT TCAGAAACTT
CAGGAAGATG CAGTTGAGAA TGATGATTAT GATAAAGGTT TGTTGGAGGA AGTTGCTACC
AGTCATCTCA CTTTGCATAC CTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu24867
Clone ID Related Accession (Same CDS sequence) NM_001164553
Accession Version NM_001164553.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1164bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product disrupted in schizophrenia 1 protein isoform p
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from FJ804213.1. Transcript Variant: This variant (p) lacks multiple 3' exons but has an alternate 3' exon, as compared to variant L. The resulting isoform (p, also known as isoform 43) is much shorter and has a distinct C-terminus, as compared to isoform L. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: FJ804213.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
ATGCCAGGCG GGGGTCCTCA GGGCGCCCCA GCCGCCGCCG GCGGCGGCGG CGTGAGCCAC 
CGCGCAGGCA GCCGGGATTG CTTACCACCT GCAGCGTGCT TTCGGAGGCG GCGGCTGGCA
CGGAGGCCGG GCTACATGAG AAGCTCGACA GGGCCTGGGA TCGGGTTCCT TTCCCCAGCA
GTGGGCACAC TGTTCCGGTT CCCAGGAGGG GTGTCTGGCG AGGAGTCCCA CCACTCGGAG
TCCAGGGCCA GACAGTGTGG CCTTGACTCG AGAGGCCTCT TGGTCCGGAG CCCTGTTTCC
AAGAGTGCAG CAGCCCCTAC TGTGACCTCT GTGAGAGGAA CCTCGGCGCA CTTTGGGATT
CAGCTCAGAG GTGGCACCAG ATTGCCTGAC AGGCTTAGCT GGCCGTGTGG CCCTGGGAGT
GCTGGGTGGC AGCAAGAGTT TGCAGCCATG GATAGTTCTG AGACCCTGGA CGCCAGCTGG
GAGGCAGCCT GCAGCGATGG AGCAAGGCGT GTCCGGGCAG CAGGCTCTCT GCCATCAGCA
GAGTTGAGTA GCAACAGCTG CAGCCCTGGC TGTGGCCCTG AGGTCCCCCC AACCCCTCCT
GGCTCTCACA GTGCCTTTAC CTCAAGCTTT AGCTTTATTC GGCTCTCGCT TGGCTCTGCC
GGGGAACGTG GAGAAGCAGA AGGCTGCCCA CCATCCAGAG AGGCTGAGTC CCATTGCCAG
AGCCCCCAGG AGATGGGAGC CAAAGCTGCC AGCTTGGACG GGCCTCACGA GGACCCGCGA
TGTCTCTCTC GGCCCTTCAG TCTCTTGGCT ACACGGGTCT CTGCAGACTT GGCCCAGGCC
GCAAGGAACA GCTCCAGGCC AGAGCGTGAC ATGCATTCTT TACCAGACAT GGACCCTGGC
TCCTCCAGTT CTCTGGATCC CTCACTGGCT GGCTGTGGTG GTGATGGGAG CAGCGGCTCA
GGGGATGCCC ACTCTTGGGA CACCCTGCTC AGGAAATGGG AGCCAGTGCT GCGGGACTGC
CTGCTGAGAA ACCGGAGGCA GATGGAGGTA ATATCCTTAA GATTAAAACT TCAGAAACTT
CAGGAAGATG CAGTTGAGAA TGATGATTAT GATAAAGCTG GAACCAATTG CTTTGGATCC
ACCATGGAAG CCTCGACATC CTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001158025.1
CDS54..1217
Misc Feature(1)54..929(+)
Exon (1)1..120
Gene:DISC1
Gene Synonym:
Exon (2)121..1100
Gene:DISC1
Gene Synonym:
Exon (3)1101..1170
Gene:DISC1
Gene Synonym:
Exon (4)1171..2706
Gene:DISC1
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001164553
Organism Homo sapiens (human)
Definition Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant p, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001164553

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
ATGCCAGGCG GGGGTCCTCA GGGCGCCCCA GCCGCCGCCG GCGGCGGCGG CGTGAGCCAC 
CGCGCAGGCA GCCGGGATTG CTTACCACCT GCAGCGTGCT TTCGGAGGCG GCGGCTGGCA
CGGAGGCCGG GCTACATGAG AAGCTCGACA GGGCCTGGGA TCGGGTTCCT TTCCCCAGCA
GTGGGCACAC TGTTCCGGTT CCCAGGAGGG GTGTCTGGCG AGGAGTCCCA CCACTCGGAG
TCCAGGGCCA GACAGTGTGG CCTTGACTCG AGAGGCCTCT TGGTCCGGAG CCCTGTTTCC
AAGAGTGCAG CAGCCCCTAC TGTGACCTCT GTGAGAGGAA CCTCGGCGCA CTTTGGGATT
CAGCTCAGAG GTGGCACCAG ATTGCCTGAC AGGCTTAGCT GGCCGTGTGG CCCTGGGAGT
GCTGGGTGGC AGCAAGAGTT TGCAGCCATG GATAGTTCTG AGACCCTGGA CGCCAGCTGG
GAGGCAGCCT GCAGCGATGG AGCAAGGCGT GTCCGGGCAG CAGGCTCTCT GCCATCAGCA
GAGTTGAGTA GCAACAGCTG CAGCCCTGGC TGTGGCCCTG AGGTCCCCCC AACCCCTCCT
GGCTCTCACA GTGCCTTTAC CTCAAGCTTT AGCTTTATTC GGCTCTCGCT TGGCTCTGCC
GGGGAACGTG GAGAAGCAGA AGGCTGCCCA CCATCCAGAG AGGCTGAGTC CCATTGCCAG
AGCCCCCAGG AGATGGGAGC CAAAGCTGCC AGCTTGGACG GGCCTCACGA GGACCCGCGA
TGTCTCTCTC GGCCCTTCAG TCTCTTGGCT ACACGGGTCT CTGCAGACTT GGCCCAGGCC
GCAAGGAACA GCTCCAGGCC AGAGCGTGAC ATGCATTCTT TACCAGACAT GGACCCTGGC
TCCTCCAGTT CTCTGGATCC CTCACTGGCT GGCTGTGGTG GTGATGGGAG CAGCGGCTCA
GGGGATGCCC ACTCTTGGGA CACCCTGCTC AGGAAATGGG AGCCAGTGCT GCGGGACTGC
CTGCTGAGAA ACCGGAGGCA GATGGAGGTA ATATCCTTAA GATTAAAACT TCAGAAACTT
CAGGAAGATG CAGTTGAGAA TGATGATTAT GATAAAGCTG GAACCAATTG CTTTGGATCC
ACCATGGAAG CCTCGACATC CTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu24941
Clone ID Related Accession (Same CDS sequence) NM_001164554
Accession Version NM_001164554.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1128bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product disrupted in schizophrenia 1 protein isoform q
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from FJ804216.1. Transcript Variant: This variant (q) lacks multiple 3' exons but has an alternate 3' segment, as compared to variant L. The resulting isoform (q, also known as isoform 46) is much shorter and has a distinct C-terminus, as compared to isoform L. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: FJ804216.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2142348 [ECO:0000348] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
ATGCCAGGCG GGGGTCCTCA GGGCGCCCCA GCCGCCGCCG GCGGCGGCGG CGTGAGCCAC 
CGCGCAGGCA GCCGGGATTG CTTACCACCT GCAGCGTGCT TTCGGAGGCG GCGGCTGGCA
CGGAGGCCGG GCTACATGAG AAGCTCGACA GGGCCTGGGA TCGGGTTCCT TTCCCCAGCA
GTGGGCACAC TGTTCCGGTT CCCAGGAGGG GTGTCTGGCG AGGAGTCCCA CCACTCGGAG
TCCAGGGCCA GACAGTGTGG CCTTGACTCG AGAGGCCTCT TGGTCCGGAG CCCTGTTTCC
AAGAGTGCAG CAGCCCCTAC TGTGACCTCT GTGAGAGGAA CCTCGGCGCA CTTTGGGATT
CAGCTCAGAG GTGGCACCAG ATTGCCTGAC AGGCTTAGCT GGCCGTGTGG CCCTGGGAGT
GCTGGGTGGC AGCAAGAGTT TGCAGCCATG GATAGTTCTG AGACCCTGGA CGCCAGCTGG
GAGGCAGCCT GCAGCGATGG AGCAAGGCGT GTCCGGGCAG CAGGCTCTCT GCCATCAGCA
GAGTTGAGTA GCAACAGCTG CAGCCCTGGC TGTGGCCCTG AGGTCCCCCC AACCCCTCCT
GGCTCTCACA GTGCCTTTAC CTCAAGCTTT AGCTTTATTC GGCTCTCGCT TGGCTCTGCC
GGGGAACGTG GAGAAGCAGA AGGCTGCCCA CCATCCAGAG AGGCTGAGTC CCATTGCCAG
AGCCCCCAGG AGATGGGAGC CAAAGCTGCC AGCTTGGACG GGCCTCACGA GGACCCGCGA
TGTCTCTCTC GGCCCTTCAG TCTCTTGGCT ACACGGGTCT CTGCAGACTT GGCCCAGGCC
GCAAGGAACA GCTCCAGGCC AGAGCGTGAC ATGCATTCTT TACCAGACAT GGACCCTGGC
TCCTCCAGTT CTCTGGATCC CTCACTGGCT GGCTGTGGTG GTGATGGGAG CAGCGGCTCA
GGGGATGCCC ACTCTTGGGA CACCCTGCTC AGGAAATGGG AGCCAGTGCT GCGGGACTGC
CTGCTGAGAA ACCGGAGGCA GATGGAGGTA ATATCCTTAA GATTAAAACT TCAGAAACTT
CAGGAAGATG CAGTTGAGAA TGATGATTAT GATAAAGGTG AGTTTTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001158026.1
CDS54..1181
Misc Feature(1)54..929(+)
Exon (1)1..120
Gene:DISC1
Gene Synonym:
Exon (2)121..1100
Gene:DISC1
Gene Synonym:
Exon (3)1101..1707
Gene:DISC1
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001164554
Organism Homo sapiens (human)
Definition Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant q, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001164554

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
ATGCCAGGCG GGGGTCCTCA GGGCGCCCCA GCCGCCGCCG GCGGCGGCGG CGTGAGCCAC 
CGCGCAGGCA GCCGGGATTG CTTACCACCT GCAGCGTGCT TTCGGAGGCG GCGGCTGGCA
CGGAGGCCGG GCTACATGAG AAGCTCGACA GGGCCTGGGA TCGGGTTCCT TTCCCCAGCA
GTGGGCACAC TGTTCCGGTT CCCAGGAGGG GTGTCTGGCG AGGAGTCCCA CCACTCGGAG
TCCAGGGCCA GACAGTGTGG CCTTGACTCG AGAGGCCTCT TGGTCCGGAG CCCTGTTTCC
AAGAGTGCAG CAGCCCCTAC TGTGACCTCT GTGAGAGGAA CCTCGGCGCA CTTTGGGATT
CAGCTCAGAG GTGGCACCAG ATTGCCTGAC AGGCTTAGCT GGCCGTGTGG CCCTGGGAGT
GCTGGGTGGC AGCAAGAGTT TGCAGCCATG GATAGTTCTG AGACCCTGGA CGCCAGCTGG
GAGGCAGCCT GCAGCGATGG AGCAAGGCGT GTCCGGGCAG CAGGCTCTCT GCCATCAGCA
GAGTTGAGTA GCAACAGCTG CAGCCCTGGC TGTGGCCCTG AGGTCCCCCC AACCCCTCCT
GGCTCTCACA GTGCCTTTAC CTCAAGCTTT AGCTTTATTC GGCTCTCGCT TGGCTCTGCC
GGGGAACGTG GAGAAGCAGA AGGCTGCCCA CCATCCAGAG AGGCTGAGTC CCATTGCCAG
AGCCCCCAGG AGATGGGAGC CAAAGCTGCC AGCTTGGACG GGCCTCACGA GGACCCGCGA
TGTCTCTCTC GGCCCTTCAG TCTCTTGGCT ACACGGGTCT CTGCAGACTT GGCCCAGGCC
GCAAGGAACA GCTCCAGGCC AGAGCGTGAC ATGCATTCTT TACCAGACAT GGACCCTGGC
TCCTCCAGTT CTCTGGATCC CTCACTGGCT GGCTGTGGTG GTGATGGGAG CAGCGGCTCA
GGGGATGCCC ACTCTTGGGA CACCCTGCTC AGGAAATGGG AGCCAGTGCT GCGGGACTGC
CTGCTGAGAA ACCGGAGGCA GATGGAGGTA ATATCCTTAA GATTAAAACT TCAGAAACTT
CAGGAAGATG CAGTTGAGAA TGATGATTAT GATAAAGGTG AGTTTTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu24731
Clone ID Related Accession (Same CDS sequence) NM_001164555
Accession Version NM_001164555.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1071bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product disrupted in schizophrenia 1 protein isoform r
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from FJ804212.1. Transcript Variant: This variant (r) lacks an internal exon and multiple 3' exons but has an alternate 3' segment, as compared to variant L. The resulting isoform (r, also known as isoform 42) is much shorter and has a distinct C-terminus, as compared to isoform L. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: FJ804212.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1968540, SAMEA2142348 [ECO:0000350] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGCCAGGCG GGGGTCCTCA GGGCGCCCCA GCCGCCGCCG GCGGCGGCGG CGTGAGCCAC 
CGCGCAGGCA GCCGGGATTG CTTACCACCT GCAGCGTGCT TTCGGAGGCG GCGGCTGGCA
CGGAGGCCGG GCTACATGAG AAGCTCGACA GGGCCTGGGA TCGGGTTCCT TTCCCCAGCA
GTGGGCACAC TGTTCCGGTT CCCAGGAGGG GTGTCTGGCG AGGAGTCCCA CCACTCGGAG
TCCAGGGCCA GACAGTGTGG CCTTGACTCG AGAGGCCTCT TGGTCCGGAG CCCTGTTTCC
AAGAGTGCAG CAGCCCCTAC TGTGACCTCT GTGAGAGGAA CCTCGGCGCA CTTTGGGATT
CAGCTCAGAG GTGGCACCAG ATTGCCTGAC AGGCTTAGCT GGCCGTGTGG CCCTGGGAGT
GCTGGGTGGC AGCAAGAGTT TGCAGCCATG GATAGTTCTG AGACCCTGGA CGCCAGCTGG
GAGGCAGCCT GCAGCGATGG AGCAAGGCGT GTCCGGGCAG CAGGCTCTCT GCCATCAGCA
GAGTTGAGTA GCAACAGCTG CAGCCCTGGC TGTGGCCCTG AGGTCCCCCC AACCCCTCCT
GGCTCTCACA GTGCCTTTAC CTCAAGCTTT AGCTTTATTC GGCTCTCGCT TGGCTCTGCC
GGGGAACGTG GAGAAGCAGA AGGCTGCCCA CCATCCAGAG AGGCTGAGTC CCATTGCCAG
AGCCCCCAGG AGATGGGAGC CAAAGCTGCC AGCTTGGACG GGCCTCACGA GGACCCGCGA
TGTCTCTCTC GGCCCTTCAG TCTCTTGGCT ACACGGGTCT CTGCAGACTT GGCCCAGGCC
GCAAGGAACA GCTCCAGGCC AGAGCGTGAC ATGCATTCTT TACCAGACAT GGACCCTGGC
TCCTCCAGTT CTCTGGATCC CTCACTGGCT GGCTGTGGTG GTGATGGGAG CAGCGGCTCA
GGGGATGCCC ACTCTTGGGA CACCCTGCTC AGGAAATGGG AGCCAGTGCT GCGGGACTGC
CTGCTGAGAA ACCGGAGGCA GATGGAGCTG AGACGTTACA ACAAAGATTA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001158027.1
CDS54..1124
Misc Feature(1)54..929(+)
Exon (1)1..120
Gene:DISC1
Gene Synonym:
Exon (2)121..1100
Gene:DISC1
Gene Synonym:
Exon (3)1101..1794
Gene:DISC1
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001164555
Organism Homo sapiens (human)
Definition Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant r, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001164555

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGCCAGGCG GGGGTCCTCA GGGCGCCCCA GCCGCCGCCG GCGGCGGCGG CGTGAGCCAC 
CGCGCAGGCA GCCGGGATTG CTTACCACCT GCAGCGTGCT TTCGGAGGCG GCGGCTGGCA
CGGAGGCCGG GCTACATGAG AAGCTCGACA GGGCCTGGGA TCGGGTTCCT TTCCCCAGCA
GTGGGCACAC TGTTCCGGTT CCCAGGAGGG GTGTCTGGCG AGGAGTCCCA CCACTCGGAG
TCCAGGGCCA GACAGTGTGG CCTTGACTCG AGAGGCCTCT TGGTCCGGAG CCCTGTTTCC
AAGAGTGCAG CAGCCCCTAC TGTGACCTCT GTGAGAGGAA CCTCGGCGCA CTTTGGGATT
CAGCTCAGAG GTGGCACCAG ATTGCCTGAC AGGCTTAGCT GGCCGTGTGG CCCTGGGAGT
GCTGGGTGGC AGCAAGAGTT TGCAGCCATG GATAGTTCTG AGACCCTGGA CGCCAGCTGG
GAGGCAGCCT GCAGCGATGG AGCAAGGCGT GTCCGGGCAG CAGGCTCTCT GCCATCAGCA
GAGTTGAGTA GCAACAGCTG CAGCCCTGGC TGTGGCCCTG AGGTCCCCCC AACCCCTCCT
GGCTCTCACA GTGCCTTTAC CTCAAGCTTT AGCTTTATTC GGCTCTCGCT TGGCTCTGCC
GGGGAACGTG GAGAAGCAGA AGGCTGCCCA CCATCCAGAG AGGCTGAGTC CCATTGCCAG
AGCCCCCAGG AGATGGGAGC CAAAGCTGCC AGCTTGGACG GGCCTCACGA GGACCCGCGA
TGTCTCTCTC GGCCCTTCAG TCTCTTGGCT ACACGGGTCT CTGCAGACTT GGCCCAGGCC
GCAAGGAACA GCTCCAGGCC AGAGCGTGAC ATGCATTCTT TACCAGACAT GGACCCTGGC
TCCTCCAGTT CTCTGGATCC CTCACTGGCT GGCTGTGGTG GTGATGGGAG CAGCGGCTCA
GGGGATGCCC ACTCTTGGGA CACCCTGCTC AGGAAATGGG AGCCAGTGCT GCGGGACTGC
CTGCTGAGAA ACCGGAGGCA GATGGAGCTG AGACGTTACA ACAAAGATTA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism
Nat Commun 5, 3650 (2014)
Corominas R, Yang X, Lin GN, Kang S, Shen Y, Ghamsari L, Broly M, Rodriguez M, Tam S, Trigg SA, Fan C, Yi S, Tasan M, Lemmens I, Kuang X, Zhao N, Malhotra D, Michaelson JJ, Vacic V, Calderwood MA, Roth FP, Tavernier J, Horvath S, Salehi-Ashtiani K, Korkin D, Sebat J, Hill DE, Hao T, Vidal M and Iakoucheva LM.


book

Revisiting disrupted-in-schizophrenia 1 as a scaffold protein
Biol. Chem. 394 (11), 1425-1437 (2013)
Yerabham,A.S., Weiergraber,O.H., Bradshaw,N.J. and Korth,C.


book

DISC1 and SLC12A2 interaction affects human hippocampal function and connectivity
J. Clin. Invest. 123 (7), 2961-2964 (2013)
Callicott JH, Feighery EL, Mattay VS, White MG, Chen Q, Baranger DA, Berman KF, Lu B, Song H, Ming GL and Weinberger DR.


book

Human brain imaging studies of DISC1 in schizophrenia, bipolar disorder and depression: a systematic review
Schizophr. Res. 147 (1), 1-13 (2013)
Duff BJ, Macritchie KA, Moorhead TW, Lawrie SM and Blackwood DH.


book

Maternal immune activation during gestation interacts with Disc1 point mutation to exacerbate schizophrenia-related behaviors in mice
J. Neurosci. 33 (18), 7654-7666 (2013)
Lipina TV, Zai C, Hlousek D, Roder JC and Wong AH.


book

Disrupted-in-Schizophrenia-1 (DISC-1): mutant truncation prevents binding to NudE-like (NUDEL) and inhibits neurite outgrowth
Proc. Natl. Acad. Sci. U.S.A. 100 (1), 289-294 (2003)
Ozeki Y, Tomoda T, Kleiderlein J, Kamiya A, Bord L, Fujii K, Okawa M, Yamada N, Hatten ME, Snyder SH, Ross CA and Sawa A.


book

Schizophrenia and affective disorders--cosegregation with a translocation at chromosome 1q42 that directly disrupts brain-expressed genes: clinical and P300 findings in a family
Am. J. Hum. Genet. 69 (2), 428-433 (2001)
Blackwood DH, Fordyce A, Walker MT, St Clair DM, Porteous DJ and Muir WJ.


book

Chromosome 1 loci in Finnish schizophrenia families
Hum. Mol. Genet. 10 (15), 1611-1617 (2001)
Ekelund J, Hovatta I, Parker A, Paunio T, Varilo T, Martin R, Suhonen J, Ellonen P, Chan G, Sinsheimer JS, Sobel E, Juvonen H, Arajarvi R, Partonen T, Suvisaari J, Lonnqvist J, Meyer J and Peltonen L.


book

Chromosomal location and genomic structure of the human translin-associated factor X gene (TRAX; TSNAX) revealed by intergenic splicing to DISC1, a gene disrupted by a translocation segregating with schizophrenia
Genomics 67 (1), 69-77 (2000)
Millar JK, Christie S, Semple CA and Porteous DJ.


book

Disruption of two novel genes by a translocation co-segregating with schizophrenia
Hum. Mol. Genet. 9 (9), 1415-1423 (2000)
Millar JK, Wilson-Annan JC, Anderson S, Christie S, Taylor MS, Semple CA, Devon RS, St Clair DM, Muir WJ, Blackwood DH and Porteous DJ.


 
*
*
*
*