×

EIF3K cDNA ORF clone, Homo sapiens (human)

Gene Symbol EIF3K
Entrez Gene ID 27335
Full Name eukaryotic translation initiation factor 3, subunit K
Synonyms ARG134, EIF3-p28, EIF3S12, HSPC029, M9, MSTP001, PLAC-24, PLAC24, PRO1474, PTD001
General protein information
Preferred Names
eukaryotic translation initiation factor 3 subunit K
Names
eukaryotic translation initiation factor 3 subunit K
eIF-3 p25
eIF-3 p28
muscle specific
muscle-specific gene M9 protein
eukaryotic translation initiation factor 3 subunit 12
eukaryotic translation initiation factor 3, subunit 12
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

19

19q13.2

Summary The 700-kD eukaryotic translation initiation factor-3 (eIF3) is the largest eIF and contains at least 12 subunits, including EIF2S12. eIF3 plays an essential role in translation by binding directly to the 40S ribosomal subunit and promoting formation of the 40S preinitiation complex (Mayeur et al., 2003 [PubMed 14519125]).[supplied by OMIM, Mar 2008]. lac of sum
Disorder MIM:

609596

Disorder Html:





The following EIF3K gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the EIF3K cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu30125 NM_013234 Homo sapiens eukaryotic translation initiation factor 3, subunit K (EIF3K), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$69.30
$99.00
OHu52170 NM_001300992 Homo sapiens eukaryotic translation initiation factor 3, subunit K (EIF3K), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $99.00
OHu67213 NM_001308393 Homo sapiens eukaryotic translation initiation factor 3, subunit K (EIF3K), transcript variant 3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $99.00

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu30125
Accession Version NM_013234.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 657bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product eukaryotic translation initiation factor 3 subunit K isoform 1
Comment VALIDATED REFSEQ: This record has undergone validation or preliminary review. This record has been curated by NCBI staff in collaboration with Francesco Amaldi. The reference sequence was derived from BG943109.1, BC001031.2, AI054400.1 and BF965565.1. On Jul 17, 2014 this sequence version replaced gi:83656777. Summary: The 700-kD eukaryotic translation initiation factor-3 (eIF3) is the largest eIF and contains at least 12 subunits, including EIF2S12. eIF3 plays an essential role in translation by binding directly to the 40S ribosomal subunit and promoting formation of the 40S preinitiation complex (Mayeur et al., 2003 [PubMed 14519125]).[supplied by OMIM, Mar 2008]. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BF965565.1, AF085358.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

1
61
121
181
241
301
361
421
481
541
601
ATGGCGATGT TTGAGCAGAT GAGAGCCAAC GTGGGCAAGT TGCTCAAGGG TATCGACAGG 
TACAATCCTG AGAACCTGGC CACCCTGGAG CGCTATGTAG AGACGCAGGC CAAGGAAAAT
GCCTATGATC TGGAAGCCAA CCTGGCTGTC CTGAAGCTGT ACCAGTTCAA CCCAGCCTTC
TTTCAGACCA CGGTCACCGC CCAGATCCTG CTGAAGGCCC TCACCAACTT GCCGCACACA
GACTTCACCC TGTGCAAGTG CATGATCGAC CAGGCACATC AAGAAGAACG GCCAATCCGA
CAGATTTTGT ACCTCGGGGA CCTGCTGGAG ACCTGCCATT TCCAGGCCTT CTGGCAAGCC
CTGGATGAAA ACATGGACCT CTTGGAAGGT ATAACTGGCT TTGAAGACTC TGTCCGAAAG
TTTATCTGCC ATGTTGTGGG TATCACTTAC CAGCACATTG ACCGCTGGCT GCTGGCCGAG
ATGCTCGGGG ATCTGTCGGA CAGCCAGCTA AAGGTGTGGA TGAGCAAATA CGGCTGGAGT
GCCGACGAGT CGGGGCAGAT CTTCATCTGT AGCCAAGAAG AGAGCATTAA ACCCAAGAAC
ATTGTGGAGA AGATTGACTT TGACAGTGTG TCCAGCATCA TGGCCTCCTC CCAGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqNP_037366.1
CDS196..852
Misc Feature(1)199..201(+)
Misc Feature(2)256..684(+)
Misc Feature(3)373..795(+)
Misc Feature(4)841..843(+)
Misc Feature(5)844..846(+)
Misc Feature(6)844..846(+)
Exon (1)1..254
Gene:EIF3K
Gene Synonym:
Exon (2)255..353
Gene:EIF3K
Gene Synonym:
Exon (3)354..474
Gene:EIF3K
Gene Synonym:
Exon (4)475..549
Gene:EIF3K
Gene Synonym:
Exon (5)550..616
Gene:EIF3K
Gene Synonym:
Exon (6)617..694
Gene:EIF3K
Gene Synonym:
Exon (7)695..820
Gene:EIF3K
Gene Synonym:
Exon (8)821..891
Gene:EIF3K
Gene Synonym:
Translation
Position Chain Variation Link
2 2 a, c, g dbSNP:577283518
3 3 -, g dbSNP:567566137
14 14 c, t dbSNP:775356277
21 21 c, g dbSNP:544724979
38 38 c, g dbSNP:553857897
43 43 a, g dbSNP:762773520
56 56 c, g dbSNP:571928078
63 63 c, t dbSNP:757324386
69 69 c, t dbSNP:149561809
71 71 a, g dbSNP:2232993
87 87 a, t dbSNP:144299925
97 97 c, t dbSNP:140799444
122 122 a, t dbSNP:767541899
128 128 c, t dbSNP:112447585
146 146 g, t dbSNP:201812654
148 148 c, t dbSNP:2232994
149 149 a, g, t dbSNP:2232995
151 151 g, t dbSNP:372381183
152 152 c, t dbSNP:530039358
168 168 g, t dbSNP:375807765
171 171 c, t dbSNP:751734799
175 175 c, t dbSNP:369039219
190 190 a, g dbSNP:371960290
200 200 -, aa dbSNP:771747294
201 201 g, t dbSNP:745802177
206 206 c, t dbSNP:769764967
226 226 a, g dbSNP:779805764
227 227 g, t dbSNP:749037064
231 231 a, c dbSNP:2232996
235 235 c, t dbSNP:773991767
256 256 c, t dbSNP:770569519
267 267 a, g dbSNP:776082305
270 270 -, c dbSNP:759361082
271 271 c, g, t dbSNP:763429199
274 274 g, t dbSNP:748497272
276 276 c, t dbSNP:774619996
279 279 c, g dbSNP:762074904
280 280 c, t dbSNP:188806390
295 295 a, g dbSNP:541226358
300 300 a, g dbSNP:756123388
306 306 a, c dbSNP:766465596
314 314 a, g dbSNP:373893911
320 320 a, g dbSNP:774303606
323 323 a, g dbSNP:201883520
324 324 c, t dbSNP:145317573
327 327 a, g dbSNP:747845596
332 332 c, g dbSNP:376238584
335 335 a, c, g dbSNP:149062652
338 338 c, t dbSNP:770551416
360 360 a, g dbSNP:748705614
362 362 g, t dbSNP:772417306
373 373 c, t dbSNP:143069816
380 380 a, t dbSNP:371604503
381 381 g, t dbSNP:551773173
386 386 c, t dbSNP:776940801
387 387 a, g dbSNP:376704723
390 390 c, t dbSNP:765371584
393 393 c, t dbSNP:560879698
394 394 a, g dbSNP:763050430
395 395 a, c dbSNP:527874937
403 403 c, t dbSNP:751450442
415 415 c, t dbSNP:757141246
417 417 c, t dbSNP:369118132
427 427 c, g dbSNP:750097473
428 428 c, t dbSNP:755525112
429 429 a, g dbSNP:779676297
435 435 g, t dbSNP:1141727
438 438 c, t dbSNP:748654759
462 462 c, t dbSNP:138683949
463 463 a, g dbSNP:752707777
465 465 c, t dbSNP:747309675
473 473 a, g dbSNP:771318333
475 475 a, c dbSNP:78190827
483 483 a, g dbSNP:1141726
485 485 a, g dbSNP:773122379
490 490 a, g dbSNP:760986345
492 492 c, g dbSNP:765993963
493 493 c, g, t dbSNP:375893694
494 494 a, g dbSNP:764778412
499 499 a, g, t dbSNP:752032430
500 500 c, t dbSNP:781396973
504 504 a, g dbSNP:369972003
510 510 c, t dbSNP:746185236
511 511 a, g dbSNP:766512679
513 513 g, t dbSNP:756437643
526 526 a, c dbSNP:780381404
528 528 c, t dbSNP:749541807
531 531 c, t dbSNP:768831666
541 541 g, t dbSNP:565785218
543 543 -, ctt dbSNP:756653904
553 553 g, t dbSNP:755314834
559 559 a, g dbSNP:779118327
568 568 a, g dbSNP:748196613
580 580 g, t dbSNP:772079164
585 585 -, t dbSNP:749679284
590 590 c, t dbSNP:370407696
598 598 a, g dbSNP:372914594
600 600 a, g dbSNP:369298575
603 603 -, ct dbSNP:746337773
607 607 a, g dbSNP:78751736
610 610 c, t dbSNP:759176086
629 629 c, t dbSNP:775158784
631 631 a, g dbSNP:200052604
640 640 -, actt dbSNP:746518687
653 653 c, t dbSNP:768178719
658 658 c, t dbSNP:371972989
659 659 a, g dbSNP:547512433
663 663 a, g dbSNP:201324415
670 670 a, g dbSNP:766930878
672 672 c, t dbSNP:147020583
673 673 a, g dbSNP:759935141
676 676 a, c dbSNP:765747985
681 681 c, t dbSNP:559495178
686 686 a, t dbSNP:746706017
692 692 c, t dbSNP:375272283
703 703 c, g dbSNP:775777468
705 705 a, g dbSNP:763389970
709 709 a, g dbSNP:557471828
711 711 a, g dbSNP:141773032
714 714 c, g dbSNP:377082891
726 726 c, t dbSNP:150144747
727 727 a, g dbSNP:750327625
731 731 a, g dbSNP:201343431
733 733 a, g dbSNP:77863139
734 734 a, g dbSNP:199953066
735 735 g, t dbSNP:748974161
737 737 c, g dbSNP:754803238
738 738 c, t dbSNP:778383566
739 739 a, g dbSNP:138580388
741 741 c, t dbSNP:771679583
744 744 a, g dbSNP:200004532
746 746 a, c, t dbSNP:746364792
747 747 a, g dbSNP:776069139
748 748 a, g dbSNP:763187879
750 750 a, g dbSNP:373079379
754 754 a, t dbSNP:774534798
767 767 c, g dbSNP:149596689
776 776 a, t dbSNP:11558208
777 777 a, g dbSNP:11558217
794 794 a, g dbSNP:767576459
795 795 c, t dbSNP:201743234
798 798 c, t dbSNP:760818702
804 804 a, g dbSNP:377673715
806 806 a, g dbSNP:112371818
809 809 c, t dbSNP:200335367
828 828 c, t dbSNP:201760106
839 839 a, c, t dbSNP:747761830
845 845 c, t dbSNP:766532978
846 846 c, t dbSNP:200802866
848 848 a, c dbSNP:753692671
849 849 c, g dbSNP:200576883
853 853 c, t dbSNP:759587776
855 855 g, t dbSNP:765114656
862 862 c, t dbSNP:752484688
886 886 a, c dbSNP:113951699
887 887 a, c dbSNP:113024296

Target ORF information:

RefSeq Version NM_013234
Organism Homo sapiens (human)
Definition Homo sapiens eukaryotic translation initiation factor 3, subunit K (EIF3K), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_013234

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
ATGGCGATGT TTGAGCAGAT GAGAGCCAAC GTGGGCAAGT TGCTCAAGGG TATCGACAGG 
TACAATCCTG AGAACCTGGC CACCCTGGAG CGCTATGTAG AGACGCAGGC CAAGGAAAAT
GCCTATGATC TGGAAGCCAA CCTGGCTGTC CTGAAGCTGT ACCAGTTCAA CCCAGCCTTC
TTTCAGACCA CGGTCACCGC CCAGATCCTG CTGAAGGCCC TCACCAACTT GCCGCACACA
GACTTCACCC TGTGCAAGTG CATGATCGAC CAGGCACATC AAGAAGAACG GCCAATCCGA
CAGATTTTGT ACCTCGGGGA CCTGCTGGAG ACCTGCCATT TCCAGGCCTT CTGGCAAGCC
CTGGATGAAA ACATGGACCT CTTGGAAGGT ATAACTGGCT TTGAAGACTC TGTCCGAAAG
TTTATCTGCC ATGTTGTGGG TATCACTTAC CAGCACATTG ACCGCTGGCT GCTGGCCGAG
ATGCTCGGGG ATCTGTCGGA CAGCCAGCTA AAGGTGTGGA TGAGCAAATA CGGCTGGAGT
GCCGACGAGT CGGGGCAGAT CTTCATCTGT AGCCAAGAAG AGAGCATTAA ACCCAAGAAC
ATTGTGGAGA AGATTGACTT TGACAGTGTG TCCAGCATCA TGGCCTCCTC CCAGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu52170
Accession Version NM_001300992.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 579bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product eukaryotic translation initiation factor 3 subunit K isoform 2
Comment VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BG943109.1, BG470776.1, JX870647.1, AI054400.1 and BF965565.1. On Jul 17, 2014 this sequence version replaced gi:578834290. Summary: The 700-kD eukaryotic translation initiation factor-3 (eIF3) is the largest eIF and contains at least 12 subunits, including EIF2S12. eIF3 plays an essential role in translation by binding directly to the 40S ribosomal subunit and promoting formation of the 40S preinitiation complex (Mayeur et al., 2003 [PubMed 14519125]).[supplied by OMIM, Mar 2008]. Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 3' coding region, compared to variant 1. It encodes isoform 2, which lacks an internal segment and is shorter, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BG470776.1, BE382785.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
ATGGCGATGT TTGAGCAGAT GAGAGCCAAC GTGGGCAAGT TGCTCAAGGG TATCGACAGG 
TACAATCCTG AGAACCTGGC CACCCTGGAG CGCTATGTAG AGACGCAGGC CAAGGAAAAT
GCCTATGATC TGGAAGCCAA CCTGGCTGTC CTGAAGCTGT ACCAGTTCAA CCCAGCCTTC
TTTCAGACCA CGGTCACCGC CCAGATCCTG CTGAAGGCCC TCACCAACTT GCCGCACACA
GACTTCACCC TGTGCAAGTG CATGATCGAC CAGGCACATC AAGAAGAACG GCCAATCCGA
CAGATTTTGT ACCTCGGGGA CCTGCTGGAG ACCTGCCATT TCCAGGCCTT CTGGCAAGCC
CTGGATGAAA ACATGGACCT CTTGGAAGGT ATAACTGGCT TTGAAGACTC TGTCCGAAAG
TACAGCCAGC TAAAGGTGTG GATGAGCAAA TACGGCTGGA GTGCCGACGA GTCGGGGCAG
ATCTTCATCT GTAGCCAAGA AGAGAGCATT AAACCCAAGA ACATTGTGGA GAAGATTGAC
TTTGACAGTG TGTCCAGCAT CATGGCCTCC TCCCAGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqNP_001287921.1
CDS196..774
Misc Feature(1)256..618(+)
Misc Feature(2)373..717(+)
Exon (1)1..254
Gene:EIF3K
Gene Synonym:
Exon (2)255..353
Gene:EIF3K
Gene Synonym:
Exon (3)354..474
Gene:EIF3K
Gene Synonym:
Exon (4)475..549
Gene:EIF3K
Gene Synonym:
Exon (5)550..616
Gene:EIF3K
Gene Synonym:
Exon (6)617..742
Gene:EIF3K
Gene Synonym:
Exon (7)743..813
Gene:EIF3K
Gene Synonym:
Translation
Position Chain Variation Link
2 2 a, c, g dbSNP:577283518
3 3 -, g dbSNP:567566137
14 14 c, t dbSNP:775356277
21 21 c, g dbSNP:544724979
38 38 c, g dbSNP:553857897
43 43 a, g dbSNP:762773520
56 56 c, g dbSNP:571928078
63 63 c, t dbSNP:757324386
69 69 c, t dbSNP:149561809
71 71 a, g dbSNP:2232993
87 87 a, t dbSNP:144299925
97 97 c, t dbSNP:140799444
122 122 a, t dbSNP:767541899
128 128 c, t dbSNP:112447585
146 146 g, t dbSNP:201812654
148 148 c, t dbSNP:2232994
149 149 a, g, t dbSNP:2232995
151 151 g, t dbSNP:372381183
152 152 c, t dbSNP:530039358
168 168 g, t dbSNP:375807765
171 171 c, t dbSNP:751734799
175 175 c, t dbSNP:369039219
190 190 a, g dbSNP:371960290
200 200 -, aa dbSNP:771747294
201 201 g, t dbSNP:745802177
206 206 c, t dbSNP:769764967
226 226 a, g dbSNP:779805764
227 227 g, t dbSNP:749037064
231 231 a, c dbSNP:2232996
235 235 c, t dbSNP:773991767
256 256 c, t dbSNP:770569519
267 267 a, g dbSNP:776082305
270 270 -, c dbSNP:759361082
271 271 c, g, t dbSNP:763429199
274 274 g, t dbSNP:748497272
276 276 c, t dbSNP:774619996
279 279 c, g dbSNP:762074904
280 280 c, t dbSNP:188806390
295 295 a, g dbSNP:541226358
300 300 a, g dbSNP:756123388
306 306 a, c dbSNP:766465596
314 314 a, g dbSNP:373893911
320 320 a, g dbSNP:774303606
323 323 a, g dbSNP:201883520
324 324 c, t dbSNP:145317573
327 327 a, g dbSNP:747845596
332 332 c, g dbSNP:376238584
335 335 a, c, g dbSNP:149062652
338 338 c, t dbSNP:770551416
360 360 a, g dbSNP:748705614
362 362 g, t dbSNP:772417306
373 373 c, t dbSNP:143069816
380 380 a, t dbSNP:371604503
381 381 g, t dbSNP:551773173
386 386 c, t dbSNP:776940801
387 387 a, g dbSNP:376704723
390 390 c, t dbSNP:765371584
393 393 c, t dbSNP:560879698
394 394 a, g dbSNP:763050430
395 395 a, c dbSNP:527874937
403 403 c, t dbSNP:751450442
415 415 c, t dbSNP:757141246
417 417 c, t dbSNP:369118132
427 427 c, g dbSNP:750097473
428 428 c, t dbSNP:755525112
429 429 a, g dbSNP:779676297
435 435 g, t dbSNP:1141727
438 438 c, t dbSNP:748654759
462 462 c, t dbSNP:138683949
463 463 a, g dbSNP:752707777
465 465 c, t dbSNP:747309675
473 473 a, g dbSNP:771318333
475 475 a, c dbSNP:78190827
483 483 a, g dbSNP:1141726
485 485 a, g dbSNP:773122379
490 490 a, g dbSNP:760986345
492 492 c, g dbSNP:765993963
493 493 c, g, t dbSNP:375893694
494 494 a, g dbSNP:764778412
499 499 a, g, t dbSNP:752032430
500 500 c, t dbSNP:781396973
504 504 a, g dbSNP:369972003
510 510 c, t dbSNP:746185236
511 511 a, g dbSNP:766512679
513 513 g, t dbSNP:756437643
526 526 a, c dbSNP:780381404
528 528 c, t dbSNP:749541807
531 531 c, t dbSNP:768831666
541 541 g, t dbSNP:565785218
543 543 -, ctt dbSNP:756653904
553 553 g, t dbSNP:755314834
559 559 a, g dbSNP:779118327
568 568 a, g dbSNP:748196613
580 580 g, t dbSNP:772079164
585 585 -, t dbSNP:749679284
590 590 c, t dbSNP:370407696
598 598 a, g dbSNP:372914594
600 600 a, g dbSNP:369298575
603 603 -, ct dbSNP:746337773
607 607 a, g dbSNP:78751736
610 610 c, t dbSNP:759176086
625 625 c, g dbSNP:775777468
627 627 a, g dbSNP:763389970
631 631 a, g dbSNP:557471828
633 633 a, g dbSNP:141773032
636 636 c, g dbSNP:377082891
648 648 c, t dbSNP:150144747
649 649 a, g dbSNP:750327625
653 653 a, g dbSNP:201343431
655 655 a, g dbSNP:77863139
656 656 a, g dbSNP:199953066
657 657 g, t dbSNP:748974161
659 659 c, g dbSNP:754803238
660 660 c, t dbSNP:778383566
661 661 a, g dbSNP:138580388
663 663 c, t dbSNP:771679583
666 666 a, g dbSNP:200004532
668 668 a, c, t dbSNP:746364792
669 669 a, g dbSNP:776069139
670 670 a, g dbSNP:763187879
672 672 a, g dbSNP:373079379
676 676 a, t dbSNP:774534798
689 689 c, g dbSNP:149596689
698 698 a, t dbSNP:11558208
699 699 a, g dbSNP:11558217
716 716 a, g dbSNP:767576459
717 717 c, t dbSNP:201743234
720 720 c, t dbSNP:760818702
726 726 a, g dbSNP:377673715
728 728 a, g dbSNP:112371818
731 731 c, t dbSNP:200335367
750 750 c, t dbSNP:201760106
761 761 a, c, t dbSNP:747761830
767 767 c, t dbSNP:766532978
768 768 c, t dbSNP:200802866
770 770 a, c dbSNP:753692671
771 771 c, g dbSNP:200576883
775 775 c, t dbSNP:759587776
777 777 g, t dbSNP:765114656
784 784 c, t dbSNP:752484688
808 808 a, c dbSNP:113951699
809 809 a, c dbSNP:113024296

Target ORF information:

RefSeq Version NM_001300992
Organism Homo sapiens (human)
Definition Homo sapiens eukaryotic translation initiation factor 3, subunit K (EIF3K), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001300992

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
ATGGCGATGT TTGAGCAGAT GAGAGCCAAC GTGGGCAAGT TGCTCAAGGG TATCGACAGG 
TACAATCCTG AGAACCTGGC CACCCTGGAG CGCTATGTAG AGACGCAGGC CAAGGAAAAT
GCCTATGATC TGGAAGCCAA CCTGGCTGTC CTGAAGCTGT ACCAGTTCAA CCCAGCCTTC
TTTCAGACCA CGGTCACCGC CCAGATCCTG CTGAAGGCCC TCACCAACTT GCCGCACACA
GACTTCACCC TGTGCAAGTG CATGATCGAC CAGGCACATC AAGAAGAACG GCCAATCCGA
CAGATTTTGT ACCTCGGGGA CCTGCTGGAG ACCTGCCATT TCCAGGCCTT CTGGCAAGCC
CTGGATGAAA ACATGGACCT CTTGGAAGGT ATAACTGGCT TTGAAGACTC TGTCCGAAAG
TACAGCCAGC TAAAGGTGTG GATGAGCAAA TACGGCTGGA GTGCCGACGA GTCGGGGCAG
ATCTTCATCT GTAGCCAAGA AGAGAGCATT AAACCCAAGA ACATTGTGGA GAAGATTGAC
TTTGACAGTG TGTCCAGCAT CATGGCCTCC TCCCAGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu67213
Accession Version NM_001308393.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 396bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 13-MAY-2015
Organism Homo sapiens (human)
Product eukaryotic translation initiation factor 3 subunit K isoform 3
Comment VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BI116511.1, BG943109.1, BG488547.1, AI054400.1 and BF965565.1. On May 5, 2015 this sequence version replaced gi:768008075. Summary: The 700-kD eukaryotic translation initiation factor-3 (eIF3) is the largest eIF and contains at least 12 subunits, including EIF2S12. eIF3 plays an essential role in translation by binding directly to the 40S ribosomal subunit and promoting formation of the 40S preinitiation complex (Mayeur et al., 2003 [PubMed 14519125]).[supplied by OMIM, Mar 2008]. Transcript Variant: This variant (3) differs in the 5' UTR and uses an alternate splice site in the 5' coding region, which results in use of a downstream start codon compared to variant 1. It encodes isoform 3, which has a shorter N-terminus than isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BM925729.1, BG488547.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
ATGATCGACC AGGCACATCA AGAAGAACGG CCAATCCGAC AGATTTTGTA CCTCGGGGAC 
CTGCTGGAGA CCTGCCATTT CCAGGCCTTC TGGCAAGCCC TGGATGAAAA CATGGACCTC
TTGGAAGGTA TAACTGGCTT TGAAGACTCT GTCCGAAAGT TTATCTGCCA TGTTGTGGGT
ATCACTTACC AGCACATTGA CCGCTGGCTG CTGGCCGAGA TGCTCGGGGA TCTGTCGGAC
AGCCAGCTAA AGGTGTGGAT GAGCAAATAC GGCTGGAGTG CCGACGAGTC GGGGCAGATC
TTCATCTGTA GCCAAGAAGA GAGCATTAAA CCCAAGAACA TTGTGGAGAA GATTGACTTT
GACAGTGTGT CCAGCATCAT GGCCTCCTCC CAGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqNP_001295322.1
CDS449..844
Misc Feature(1)209..211(+)
Misc Feature(2)449..787(+)
Misc Feature(3)452..676(+)
Exon (1)1..246
Gene:EIF3K
Gene Synonym:
Exon (2)247..345
Gene:EIF3K
Gene Synonym:
Exon (3)346..466
Gene:EIF3K
Gene Synonym:
Exon (4)467..541
Gene:EIF3K
Gene Synonym:
Exon (5)542..608
Gene:EIF3K
Gene Synonym:
Exon (6)609..686
Gene:EIF3K
Gene Synonym:
Exon (7)687..812
Gene:EIF3K
Gene Synonym:
Exon (8)813..883
Gene:EIF3K
Gene Synonym:
Translation
Position Chain Variation Link

Target ORF information:

RefSeq Version NM_001308393
Organism Homo sapiens (human)
Definition Homo sapiens eukaryotic translation initiation factor 3, subunit K (EIF3K), transcript variant 3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001308393

ORF Insert Sequence:

1
61
121
181
241
301
361
ATGATCGACC AGGCACATCA AGAAGAACGG CCAATCCGAC AGATTTTGTA CCTCGGGGAC 
CTGCTGGAGA CCTGCCATTT CCAGGCCTTC TGGCAAGCCC TGGATGAAAA CATGGACCTC
TTGGAAGGTA TAACTGGCTT TGAAGACTCT GTCCGAAAGT TTATCTGCCA TGTTGTGGGT
ATCACTTACC AGCACATTGA CCGCTGGCTG CTGGCCGAGA TGCTCGGGGA TCTGTCGGAC
AGCCAGCTAA AGGTGTGGAT GAGCAAATAC GGCTGGAGTG CCGACGAGTC GGGGCAGATC
TTCATCTGTA GCCAAGAAGA GAGCATTAAA CCCAAGAACA TTGTGGAGAA GATTGACTTT
GACAGTGTGT CCAGCATCAT GGCCTCCTCC CAGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

 
*
*
*
*