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GNGT1 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 [Homo sapiens (human)]

Gene Symbol GNGT1
Entrez Gene ID 2792
Full Name guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
Synonyms GNG1
General protein information
Preferred Names
guanine nucleotide-binding protein G(T) subunit gamma-T1
Names
guanine nucleotide-binding protein G(T) subunit gamma-T1
transducin gamma chain
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

7

7q21.3

Summary Heterotrimeric guanine nucleotide-binding proteins (G proteins) transduce extracellular signals received by transmembrane receptors to effector proteins. Transducin is a guanine nucleotide-binding protein found specifically in rod outer segments, where it mediates activation by rhodopsin of a cyclic GTP-specific (guanosine monophosphate) phosphodiesterase. Transducin is also referred to as GMPase. GNGT1 encodes the gamma subunit of transducin (Hurley et al., 1984 [PubMed 6438626]; Scherer et al., 1996 [PubMed 8661128]).[supplied by OMIM, Mar 2008]. lac of sum
Disorder MIM:

189970

Disorder Html:





The following GNGT1 gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GNGT1 gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu04853 NM_021955 Homo sapiens guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 (GNGT1), mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $99

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu04853
Accession Version NM_021955.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 225bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product guanine nucleotide-binding protein G(T) subunit gamma-T1 precursor
Comment VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC029367.1 and AC002076.2. On Sep 9, 2005 this sequence version replaced gi:41584205. Summary: Heterotrimeric guanine nucleotide-binding proteins (G proteins) transduce extracellular signals received by transmembrane receptors to effector proteins. Transducin is a guanine nucleotide-binding protein found specifically in rod outer segments, where it mediates activation by rhodopsin of a cyclic GTP-specific (guanosine monophosphate) phosphodiesterase. Transducin is also referred to as GMPase. GNGT1 encodes the gamma subunit of transducin (Hurley et al., 1984 [PubMed 6438626]; Scherer et al., 1996 [PubMed 8661128]).[supplied by OMIM, Mar 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BG435040.1, EL946418.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2149398, SAMEA2153307 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
ATGCCAGTAA TCAATATTGA GGACCTGACA GAAAAGGACA AATTGAAGAT GGAAGTTGAC 
CAGCTCAAGA AAGAAGTGAC ACTGGAAAGA ATGCTAGTTT CCAAATGTTG TGAAGAAGTA
AGAGATTACG TTGAAGAACG ATCTGGCGAG GATCCACTGG TAAAGGGCAT CCCAGAGGAC
AAAAATCCCT TCAAGGAGCT CAAAGGAGGC TGTGTGATTT CATAA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_068774.1
CDS149..373
Misc Feature(1)110..112(+)
Misc Feature(2)182..352(+)
Misc Feature(3)182..340(+)
Exon (1)1..137
Gene:GNGT1
Gene Synonym:
Exon (2)138..244
Gene:GNGT1
Gene Synonym:
Exon (3)245..628
Gene:GNGT1
Gene Synonym:
Translation
Position Chain Variation Link
39 39 c, t dbSNP:564346446
80 80 c, t dbSNP:147350641
91 91 c, t dbSNP:573732840
108 108 g, t dbSNP:542579365
140 140 c, g dbSNP:747966528
143 143 a, c dbSNP:540836125
148 148 a, g dbSNP:778843372
152 152 a, c dbSNP:746027091
153 153 c, t dbSNP:376703142
154 154 a, g dbSNP:772250512
156 156 g, t dbSNP:775641362
157 157 a, g dbSNP:191685430
163 163 c, t dbSNP:768944512
177 177 c, g, t dbSNP:776996322
185 185 a, c, g dbSNP:765842422
203 203 g, t dbSNP:762577190
205 205 c, t dbSNP:150956934
207 207 a, c dbSNP:751213457
209 209 c, g dbSNP:141065761
211 211 a, g dbSNP:781074304
224 224 g, t dbSNP:752594162
225 225 c, t dbSNP:755999687
230 230 a, c, t dbSNP:200035274
239 239 a, t dbSNP:772100965
240 240 c, t dbSNP:780114005
244 244 a, g dbSNP:202009903
259 259 c, t dbSNP:749751598
265 265 a, c, g dbSNP:202213169
278 278 a, c, g dbSNP:149827734
280 280 c, t dbSNP:767054727
282 282 a, g dbSNP:146833932
286 286 a, g dbSNP:374057761
287 287 c, t dbSNP:532358490
288 288 a, g dbSNP:535998188
290 290 c, t dbSNP:753632527
295 295 c, t dbSNP:552036514
296 296 a, c, g dbSNP:17243826
297 297 a, g dbSNP:754998799
301 301 c, t dbSNP:781165241
303 303 c, t dbSNP:748339515
304 304 a, g dbSNP:756306717
306 306 c, t dbSNP:778189581
307 307 a, g dbSNP:749739233
308 308 c, g dbSNP:771534540
309 309 c, t dbSNP:775047653
311 311 a, g dbSNP:746399500
313 313 a, g dbSNP:554239065
314 314 g, t dbSNP:771543991
315 315 g, t dbSNP:138254553
321 321 c, t dbSNP:760360120
323 323 a, g dbSNP:763718758
324 324 a, g dbSNP:776376731
340 340 a, c dbSNP:149136992
350 350 a, g dbSNP:765035469
358 358 c, t dbSNP:750316971
360 360 a, g dbSNP:143310057
361 361 c, t dbSNP:368033084
374 374 a, t dbSNP:767579385
386 386 -, a dbSNP:748949063
387 387 -, a dbSNP:768246904
393 393 a, t dbSNP:752779933
397 397 -, aaac dbSNP:774725344
398 398 a, c dbSNP:77925896
400 400 c, t dbSNP:777898529
406 406 a, c dbSNP:372563644
407 407 g, t dbSNP:757647866
408 408 a, t dbSNP:779423987
423 423 c, t dbSNP:746317789
429 429 c, t dbSNP:554472946
432 432 c, g dbSNP:748499860
439 439 a, g dbSNP:772631015
449 449 a, c dbSNP:778205326
455 455 a, g dbSNP:115265988
460 460 c, t dbSNP:747056537
464 464 a, g dbSNP:141229133
476 476 c, t dbSNP:774254934
477 477 a, c, g dbSNP:79786664
491 491 a, c, g, t dbSNP:2798
497 497 a, t dbSNP:542372552
504 504 c, t dbSNP:562148252
515 515 a, c dbSNP:572487900
531 531 c, t dbSNP:370988411
544 544 c, g dbSNP:537434585
586 586 c, t dbSNP:560398039

Target ORF information:

RefSeq Version NM_021955
Organism Homo sapiens (human)
Definition Homo sapiens guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 (GNGT1), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_021955

ORF Insert Sequence:

1
61
121
181
ATGCCAGTAA TCAATATTGA GGACCTGACA GAAAAGGACA AATTGAAGAT GGAAGTTGAC 
CAGCTCAAGA AAGAAGTGAC ACTGGAAAGA ATGCTAGTTT CCAAATGTTG TGAAGAAGTA
AGAGATTACG TTGAAGAACG ATCTGGCGAG GATCCACTGG TAAAGGGCAT CCCAGAGGAC
AAAAATCCCT TCAAGGAGCT CAAAGGAGGC TGTGTGATTT CATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.