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GPX3 cDNA ORF clone, Homo sapiens (human)

Gene Symbol GPX3
Entrez Gene ID 2878
Full Name glutathione peroxidase 3
Synonyms GPx-P, GSHPx-3, GSHPx-P
General protein information
Preferred Names
glutathione peroxidase 3
Names
glutathione peroxidase 3
GPx-3
plasma glutathione peroxidase
extracellular glutathione peroxidase
NP_002075.2
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

5

5q33.1

Summary This gene product belongs to the glutathione peroxidase family, which functions in the detoxification of hydrogen peroxide. It contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

138321

Disorder Html:





The following GPX3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GPX3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu14624 NM_002084 Homo sapiens glutathione peroxidase 3 (GPX3), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$69.30
$99.00

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu14624
Accession Version NM_002084.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 681bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product glutathione peroxidase 3 precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BI522602.1, AC008641.7 and AL036834.2. On Mar 16, 2006 this sequence version replaced gi:6006000. Summary: This gene product belongs to the glutathione peroxidase family, which functions in the detoxification of hydrogen peroxide. It contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##RefSeq-Attributes-START## protein contains selenocysteine :: inferred from conservation ##RefSeq-Attributes-END## ##Evidence-Data-START## Transcript exon combination :: BC050378.1, BC025956.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

1
61
121
181
241
301
361
421
481
541
601
661
ATGGCCCGGC TGCTGCAGGC GTCCTGCCTG CTTTCCCTGC TCCTGGCCGG CTTCGTCTCG 
CAGAGCCGGG GACAAGAGAA GTCGAAGATG GACTGCCATG GTGGCATAAG TGGCACCATT
TACGAGTACG GAGCCCTCAC CATTGATGGG GAGGAGTACA TCCCCTTCAA GCAGTATGCT
GGCAAATACG TCCTCTTTGT CAACGTGGCC AGCTACTGAG GCCTGACGGG CCAGTACATT
GAACTGAATG CACTACAGGA AGAGCTTGCA CCATTCGGTC TGGTCATTCT GGGCTTTCCC
TGCAACCAAT TTGGAAAACA GGAACCAGGA GAGAACTCAG AGATCCTTCC TACCCTCAAG
TATGTCCGAC CAGGTGGAGG CTTTGTCCCT AATTTCCAGC TCTTTGAGAA AGGGGATGTC
AATGGAGAGA AAGAGCAGAA ATTCTACACT TTCCTAAAGA ACTCCTGTCC TCCCACCTCG
GAGCTCCTGG GTACATCTGA CCGCCTCTTC TGGGAACCCA TGAAGGTTCA CGACATCCGC
TGGAACTTTG AGAAGTTCCT GGTGGGGCCA GATGGTATAC CCATCATGCG CTGGCACCAC
CGGACCACGG TCAGCAACGT CAAGATGGAC ATCCTGTCCT ACATGAGGCG GCAGGCAGCC
CTGGGGGTCA AGAGGAAGTA A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqNP_002075.2
CDS218..898
Misc Feature(1)197..199(+)
Misc Feature(2)332..850(+)
Misc Feature(3)434..760(+)
Misc Feature(4)434..436(+)
Misc Feature(5)434..436(+)
Misc Feature(6)533..580(+)
Exon (1)1..304
Gene:GPX3
Gene Synonym:
Exon (2)305..458
Gene:GPX3
Gene Synonym:
Exon (3)459..576
Gene:GPX3
Gene Synonym:
Exon (4)577..676
Gene:GPX3
Gene Synonym:
Exon (5)677..1761
Gene:GPX3
Gene Synonym:
Translation
Position Chain Variation Link
84 84 c, g dbSNP:8177411
89 89 c, t dbSNP:8177412
102 102 a, g dbSNP:572320481
118 118 a, t dbSNP:545812818
141 141 a, c dbSNP:539930404
163 163 a, g dbSNP:775612496
172 172 a, g dbSNP:769444895
175 175 -, c dbSNP:764925388
175 175 c, t dbSNP:773790387
191 191 a, c dbSNP:564914035
192 192 c, g dbSNP:771413581
205 205 c, t dbSNP:774630312
211 211 c, t dbSNP:759973366
213 213 c, t dbSNP:767581865
228 228 g, t dbSNP:775791251
233 233 c, g dbSNP:760678180
237 237 a, c, t dbSNP:764223263
238 238 a, g dbSNP:758378427
241 241 c, t dbSNP:766166494
248 248 c, t dbSNP:576871899
253 253 c, t dbSNP:754825679
256 256 c, g dbSNP:8177413
259 259 c, t dbSNP:747842654
261 261 c, t dbSNP:377617159
264 264 c, t dbSNP:777486159
265 265 c, t dbSNP:370954217
273 273 a, t dbSNP:375877920
276 276 c, t dbSNP:377710604
286 286 a, g dbSNP:746158009
287 287 c, g dbSNP:772487729
289 289 a, g, t dbSNP:775568607
301 301 a, g dbSNP:764135153
313 313 c, t dbSNP:780569082
316 316 c, t dbSNP:367725712
319 319 c, t dbSNP:769022356
331 331 c, t dbSNP:781326577
340 340 c, t dbSNP:748438053
341 341 a, g dbSNP:200128541
344 344 g, t dbSNP:773392965
346 346 c, t dbSNP:759363512
347 347 a, g dbSNP:772010208
361 361 a, t dbSNP:775577576
362 362 a, g dbSNP:760476705
365 365 a, g dbSNP:764043839
367 367 -, gga dbSNP:762659510
369 369 a, c dbSNP:753136454
370 370 c, g dbSNP:371966819
378 378 -, t dbSNP:764034885
380 380 c, g dbSNP:764620936
396 396 c, g dbSNP:749907550
398 398 a, g dbSNP:757867437
401 401 -, aa dbSNP:751560977
406 406 c, t dbSNP:766813820
420 420 a, g dbSNP:373981887
421 421 c, t dbSNP:142849792
422 422 a, g dbSNP:781596538
434 434 c, t dbSNP:748297956
443 443 a, g dbSNP:756402136
444 444 c, t dbSNP:371856135
445 445 a, g dbSNP:200228989
448 448 a, c dbSNP:770916140
454 454 c, g dbSNP:775560970
456 456 c, t dbSNP:368521899
466 466 g, t dbSNP:746922788
466 466 -, t dbSNP:750654735
487 487 a, c dbSNP:768667979
490 490 a, g dbSNP:373194048
493 493 c, t dbSNP:780695446
494 494 a, g dbSNP:769489466
500 500 a, g dbSNP:200221775
501 501 c, t dbSNP:769471948
509 509 a, g dbSNP:762577752
530 530 a, g dbSNP:765841620
530 530 -, g dbSNP:756465162
531 531 -, a dbSNP:780281557
531 531 a, g dbSNP:773898104
536 536 a, c dbSNP:759065699
537 537 a, g dbSNP:767969017
538 538 a, g dbSNP:753145475
539 539 a, g dbSNP:761091660
541 541 a, g dbSNP:200416261
548 548 c, g dbSNP:775803002
551 551 a, c dbSNP:369298257
562 562 c, g dbSNP:754063629
570 570 c, t dbSNP:757604984
571 571 c, t dbSNP:779302096
578 578 c, t dbSNP:758975709
579 579 a, g dbSNP:771492353
584 584 c, t dbSNP:776064760
585 585 a, g dbSNP:572854749
587 587 c, t dbSNP:767581466
589 589 a, c dbSNP:371422003
597 597 a, g dbSNP:754105125
598 598 a, c dbSNP:762300821
599 599 c, t dbSNP:8177445
602 602 c, g dbSNP:765489402
603 603 c, t dbSNP:540252597
616 616 c, g dbSNP:750687719
617 617 c, t dbSNP:373449699
621 621 g, t dbSNP:201249129
629 629 a, g dbSNP:752647532
631 631 a, g dbSNP:370194625
637 637 c, t dbSNP:777786115
640 640 c, t dbSNP:749039304
647 647 a, t dbSNP:11544082
650 650 a, c, g dbSNP:558592006
661 661 c, t dbSNP:745591470
664 664 c, t dbSNP:771583068
665 665 a, g dbSNP:373809425
669 669 a, t dbSNP:760257655
682 682 c, t dbSNP:758219351
683 683 c, t dbSNP:200470998
697 697 a, g dbSNP:779516716
717 717 a, c dbSNP:779157665
719 719 a, c, t dbSNP:746734937
720 720 a, g dbSNP:374193246
721 721 c, t dbSNP:748643419
724 724 a, c dbSNP:770375282
734 734 c, t dbSNP:184186742
748 748 c, t dbSNP:757168447
749 749 a, g dbSNP:556389247
756 756 c, g dbSNP:771337658
759 759 a, g dbSNP:780644613
760 760 a, g dbSNP:574927554
792 792 a, g dbSNP:759865306
802 802 c, g dbSNP:772121564
807 807 a, g, t dbSNP:372652345
817 817 c, t dbSNP:542081520
819 819 a, g dbSNP:370891492
825 825 c, t dbSNP:560735748
826 826 a, g dbSNP:375837316
831 831 c, g dbSNP:751139605
832 832 a, c dbSNP:368970475
835 835 c, t dbSNP:371559625
836 836 a, g dbSNP:752213053
841 841 c, g dbSNP:755686829
860 860 a, c, g dbSNP:778364094
864 864 a, g dbSNP:771192055
866 866 c, t dbSNP:779386671
869 869 c, t dbSNP:755744533
874 874 a, c dbSNP:746245453
884 884 a, g dbSNP:376670831
891 891 c, g dbSNP:369084683
900 900 g, t dbSNP:200511585
901 901 a, g dbSNP:200721773
907 907 c, t dbSNP:768783389
908 908 a, g dbSNP:373873682
928 928 c, t dbSNP:762988524
929 929 g, t dbSNP:750092217
936 936 a, g dbSNP:766065539
940 940 a, c dbSNP:779744863
944 944 g, t dbSNP:751318928
959 959 a, c dbSNP:759433833
960 960 c, t dbSNP:549582772
961 961 a, g dbSNP:767210839
962 962 a, t dbSNP:549807986
965 965 c, t dbSNP:1803677
971 971 c, t dbSNP:188838205
990 990 c, t dbSNP:11548
995 995 c, t dbSNP:150488167
1028 1028 c, t dbSNP:769004576
1032 1032 c, t dbSNP:766019560
1036 1036 g, t dbSNP:2230303
1042 1042 a, c dbSNP:748648039
1052 1052 c, t dbSNP:755352112
1059 1059 a, g dbSNP:7722386
1077 1077 g, t dbSNP:779314014
1084 1084 c, g dbSNP:772744768
1087 1087 a, g dbSNP:575265447
1112 1112 c, t dbSNP:758417544
1118 1118 -, tgtg dbSNP:778055125
1142 1142 a, g dbSNP:8177448
1146 1146 c, t dbSNP:8177449
1147 1147 a, g dbSNP:2070593
1153 1153 a, g dbSNP:8177450
1154 1154 c, t dbSNP:8177451
1185 1185 g, t dbSNP:535991023
1218 1218 a, g dbSNP:554387529
1267 1267 a, c dbSNP:749059886
1279 1279 a, g dbSNP:192433815
1302 1302 a, g dbSNP:79250800
1313 1313 -, ctaa dbSNP:540676660
1315 1315 -, aact dbSNP:375078202
1327 1327 a, g dbSNP:564635604
1380 1380 c, t dbSNP:555700211
1381 1381 a, g dbSNP:575946730
1387 1387 a, t dbSNP:373584330
1402 1402 -, t dbSNP:543372300
1407 1407 a, c, t dbSNP:1064506
1422 1422 a, c dbSNP:143049264
1506 1506 a, g dbSNP:8177452
1522 1522 c, t dbSNP:4661
1535 1535 a, g dbSNP:532736004
1536 1536 c, g dbSNP:17111673
1555 1555 c, t dbSNP:138719981
1556 1556 a, g dbSNP:761782252
1581 1581 a, c dbSNP:551018219
1611 1611 c, t dbSNP:1059316
1640 1640 a, c dbSNP:8177453
1657 1657 a, g dbSNP:551213547
1679 1679 c, g dbSNP:541470150
1684 1684 c, t dbSNP:569872115
1685 1685 a, g dbSNP:569554951
1728 1728 a, g dbSNP:187389496

Target ORF information:

RefSeq Version NM_002084
Organism Homo sapiens (human)
Definition Homo sapiens glutathione peroxidase 3 (GPX3), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_002084

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
ATGGCCCGGC TGCTGCAGGC GTCCTGCCTG CTTTCCCTGC TCCTGGCCGG CTTCGTCTCG 
CAGAGCCGGG GACAAGAGAA GTCGAAGATG GACTGCCATG GTGGCATAAG TGGCACCATT
TACGAGTACG GAGCCCTCAC CATTGATGGG GAGGAGTACA TCCCCTTCAA GCAGTATGCT
GGCAAATACG TCCTCTTTGT CAACGTGGCC AGCTACTGAG GCCTGACGGG CCAGTACATT
GAACTGAATG CACTACAGGA AGAGCTTGCA CCATTCGGTC TGGTCATTCT GGGCTTTCCC
TGCAACCAAT TTGGAAAACA GGAACCAGGA GAGAACTCAG AGATCCTTCC TACCCTCAAG
TATGTCCGAC CAGGTGGAGG CTTTGTCCCT AATTTCCAGC TCTTTGAGAA AGGGGATGTC
AATGGAGAGA AAGAGCAGAA ATTCTACACT TTCCTAAAGA ACTCCTGTCC TCCCACCTCG
GAGCTCCTGG GTACATCTGA CCGCCTCTTC TGGGAACCCA TGAAGGTTCA CGACATCCGC
TGGAACTTTG AGAAGTTCCT GGTGGGGCCA GATGGTATAC CCATCATGCG CTGGCACCAC
CGGACCACGG TCAGCAACGT CAAGATGGAC ATCCTGTCCT ACATGAGGCG GCAGGCAGCC
CTGGGGGTCA AGAGGAAGTA A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

 
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