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MSH6 mutS homolog 6 [Homo sapiens (human)]

Gene Symbol MSH6
Entrez Gene ID 2956
Full Name mutS homolog 6
Synonyms GTBP, GTMBP, HNPCC5, HSAP, p160
General protein information
Preferred Names
DNA mismatch repair protein Msh6
Names
DNA mismatch repair protein Msh6
p160
GTMBP
hMSH6
sperm-associated protein
mutS-alpha 160 kDa subunit
G/T mismatch-binding protein
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

2

2p16

Summary This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have been described. [provided by RefSeq, Jul 2013]. lac of sum
Disorder MIM:

600678

Disorder Html: Colorectal cancer, hereditary nonpolyposis, type 5 (3); Endometrial





The following MSH6 gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MSH6 gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu27543 NM_001281492 Homo sapiens mutS homolog 6 (MSH6), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 20 Quote Price
OHu58146 XM_011532798 PREDICTED: Homo sapiens mutS homolog 6 (MSH6), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 20 Quote Price
OHu35371 XM_011532799 PREDICTED: Homo sapiens mutS homolog 6 (MSH6), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 20 Quote Price
OHu35371 XM_011532800 PREDICTED: Homo sapiens mutS homolog 6 (MSH6), transcript variant X3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 20 Quote Price
OHu35371 XM_005264271 PREDICTED: Homo sapiens mutS homolog 6 (MSH6), transcript variant X4, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 20 Quote Price
OHu22411 NM_001281493 Homo sapiens mutS homolog 6 (MSH6), transcript variant 3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 16 Quote Price
OHu22411 NM_001281494 Homo sapiens mutS homolog 6 (MSH6), transcript variant 4, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 16 Quote Price
OHu25314 NM_000179 Homo sapiens mutS homolog 6 (MSH6), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 25 Quote Price

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**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu27543
Accession Version NM_001281492.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 3693bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector Document: User manual_GenEZ ORF Clone Products.pdf (pdf)
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags Document: MSDS_GenEZ ORF Clone Products.pdf (pdf)
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 26-MAY-2014
Organism Homo sapiens (human)
Product DNA mismatch repair protein Msh6 isoform 2
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC071594.1 and AK293921.1. Summary: This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have been described. [provided by RefSeq, Jul 2013]. Transcript Variant: This variant (2) uses an alternate splice site and lacks two exons in the 5' coding region compared to variant 1. The resulting protein (isoform 2) is shorter but has the same N- and C-termini compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK293921.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
3481
3541
3601
3661
ATGTCGCGAC AGAGCACCCT GTACAGCTTC TTCCCCAAGT CTCCGGCGCT GAGTGATGCC 
AACAAGGCCT CGGCCAGGGC CTCACGCGAA GGCGGCCGTG CCGCCGCTGC CCCCGGGGCC
TCTCCTTCCC CAGGCGGGGA TGCGGCCTGG AGCGAGGCTG GGCCTGGGCC CAGGCCCTTG
GCGCGCTCCG CGTCACCGCC CAAGGCGAAG AACCTCAACG GAGGGCTGCG GAGATCGGTA
GGCACAACTT ACGTAACAGA TAAGAGTGAA GAAGATAATG AAATTGAGAG TGAAGAGGAA
GTACAGCCTA AGACACAAGG ATCTAGGCGA AGTAGCCGCC AAATAAAAAA ACGAAGGGTC
ATATCAGATT CTGAGAGTGA CATTGGTGGC TCTGATGTGG AATTTAAGCC AGACACTAAG
GAGGAAGGAA GCAGTGATGA AATAAGCAGT GGAGTGGGGG ATAGTGAGAG TGAAGGCCTG
AACAGCCCTG TCAAAGTTGC TCGAAAGCGG AAGAGAATGG TGACTGGAAA TGGCTCTCTT
AAAAGGAAAA GCTCTAGGAA GGAAACGCCC TCAGCCACCA AACAAGCAAC TAGCATTTCA
TCAGAAACCA AGAATACTTT GAGAGCTTTC TCTGCCCCTC AAAATTCTGA ATCCCAAGCC
CACGTTAGTG GAGGTGGTGA TGACAGTAGT CGCCCTACTG TTTGGTATCA TGAAACTTTA
GAATGGCTTA AGGAGGAAAA GAGAAGAGAT GAGCACAGGA GGAGGCCTGA TCACCCCGAT
TTTGATGCAT CTACACTCTA TGTGCCTGAG GATTTCCTCA ATTCTTGTAC TCCTGGGATG
AGGAAGTGGT GGCAGATTAA GTCTCAGAAC TTTGATCTTG TCATCTGTTA CAAGGTGGGG
AAATTTTATG AGCTGTACCA CATGGATGCT CTTATTGGAG TCAGTGAACT GGGGCTGGTA
TTCATGAAAG GCAACTGGGC CCATTCTGGC TTTCCTGAAA TTGCATTTGG CCGTTATTCA
GATTCCCTGG TGCAGAAGGG CTATAAAGTA GCACGAGTGG AACAGACTGA GACTCCAGAA
ATGATGGAGG CACGATGTAG AAAGATGGCA CATATATCCA AGTATGATAG AGTGGTGAGG
AGGGAGATCT GTAGGATCAT TACCAAGGGT ACACAGACTT ACAGTGTGCT GGAAGGTGAT
CCCTCTGAGA ACTACAGTAA GTATCTTCTT AGCCTCAAAG AAAAAGAGGA AGATTCTTCT
GGCCATACTC GTGCATATGG TGTGTGCTTT GTTGATACTT CACTGGGAAA GTTTTTCATA
GGTCAGTTTT CAGATGATCG CCATTGTTCG AGATTTAGGA CTCTAGTGGC ACACTATCCC
CCAGTACAAG TTTTATTTGA AAAAGGAAAT CTCTCAAAGG AAACTAAAAC AATTCTAAAG
AGTTCATTGT CCTGTTCTCT TCAGGAAGGT CTGATACCCG GCTCCCAGTT TTGGGATGCA
TCCAAAACTT TGAGAACTCT CCTTGAGGAA GAATATTTTA GGGAAAAGCT AAGTGATGGC
ATTGGGGTGA TGTTACCCCA GGTGCTTAAA GGTATGACTT CAGAGTCTGA TTCCATTGGG
TTGACACCAG GAGAGAAAAG TGAATTGGCC CTCTCTGCTC TAGGTGGTTG TGTCTTCTAC
CTCAAAAAAT GCCTTATTGA TCAGGAGCTT TTATCAATGG CTAATTTTGA AGAATATATT
CCCTTGGATT CTGACACAGT CAGCACTACA AGATCTGGTG CTATCTTCAC CAAAGCCTAT
CAACGAATGG TGCTAGATGC AGTGACATTA AACAACTTGG AGATTTTTCT GAATGGAACA
AATGGTTCTA CTGAAGGAAC CCTACTAGAG AGGGTTGATA CTTGCCATAC TCCTTTTGGT
AAGCGGCTCC TAAAGCAATG GCTTTGTGCC CCACTCTGTA ACCATTATGC TATTAATGAT
CGTCTAGATG CCATAGAAGA CCTCATGGTT GTGCCTGACA AAATCTCCGA AGTTGTAGAG
CTTCTAAAGA AGCTTCCAGA TCTTGAGAGG CTACTCAGTA AAATTCATAA TGTTGGGTCT
CCCCTGAAGA GTCAGAACCA CCCAGACAGC AGGGCTATAA TGTATGAAGA AACTACATAC
AGCAAGAAGA AGATTATTGA TTTTCTTTCT GCTCTGGAAG GATTCAAAGT AATGTGTAAA
ATTATAGGGA TCATGGAAGA AGTTGCTGAT GGTTTTAAGT CTAAAATCCT TAAGCAGGTC
ATCTCTCTGC AGACAAAAAA TCCTGAAGGT CGTTTTCCTG ATTTGACTGT AGAATTGAAC
CGATGGGATA CAGCCTTTGA CCATGAAAAG GCTCGAAAGA CTGGACTTAT TACTCCCAAA
GCAGGCTTTG ACTCTGATTA TGACCAAGCT CTTGCTGACA TAAGAGAAAA TGAACAGAGC
CTCCTGGAAT ACCTAGAGAA ACAGCGCAAC AGAATTGGCT GTAGGACCAT AGTCTATTGG
GGGATTGGTA GGAACCGTTA CCAGCTGGAA ATTCCTGAGA ATTTCACCAC TCGCAATTTG
CCAGAAGAAT ACGAGTTGAA ATCTACCAAG AAGGGCTGTA AACGATACTG GACCAAAACT
ATTGAAAAGA AGTTGGCTAA TCTCATAAAT GCTGAAGAAC GGAGGGATGT ATCATTGAAG
GACTGCATGC GGCGACTGTT CTATAACTTT GATAAAAATT ACAAGGACTG GCAGTCTGCT
GTAGAGTGTA TCGCAGTGTT GGATGTTTTA CTGTGCCTGG CTAACTATAG TCGAGGGGGT
GATGGTCCTA TGTGTCGCCC AGTAATTCTG TTGCCGGAAG ATACCCCCCC CTTCTTAGAG
CTTAAAGGAT CACGCCATCC TTGCATTACG AAGACTTTTT TTGGAGATGA TTTTATTCCT
AATGACATTC TAATAGGCTG TGAGGAAGAG GAGCAGGAAA ATGGCAAAGC CTATTGTGTG
CTTGTTACTG GACCAAATAT GGGGGGCAAG TCTACGCTTA TGAGACAGGC TGGCTTATTA
GCTGTAATGG CCCAGATGGG TTGTTACGTC CCTGCTGAAG TGTGCAGGCT CACACCAATT
GATAGAGTGT TTACTAGACT TGGTGCCTCA GACAGAATAA TGTCAGGTGA AAGTACATTT
TTTGTTGAAT TAAGTGAAAC TGCCAGCATA CTCATGCATG CAACAGCACA TTCTCTGGTG
CTTGTGGATG AATTAGGAAG AGGTACTGCA ACATTTGATG GGACGGCAAT AGCAAATGCA
GTTGTTAAAG AACTTGCTGA GACTATAAAA TGTCGTACAT TATTTTCAAC TCACTACCAT
TCATTAGTAG AAGATTATTC TCAAAATGTT GCTGTGCGCC TAGGACATAT GGCATGCATG
GTAGAAAATG AATGTGAAGA CCCCAGCCAG GAGACTATTA CGTTCCTCTA TAAATTCATT
AAGGGAGCTT GTCCTAAAAG CTATGGCTTT AATGCAGCAA GGCTTGCTAA TCTCCCAGAG
GAAGTTATTC AAAAGGGACA TAGAAAAGCA AGAGAATTTG AGAAGATGAA TCAGTCACTA
CGATTATTTC GGGAAGTTTG CCTGGCTAGT GAAAGGTCAA CTGTAGATGC TGAAGCTGTC
CATAAATTGC TGACTTTGAT TAAGGAATTA TAG
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_001268421.1
CDS153..3845
Misc Feature(1)15..17(+)
Misc Feature(2)192..194(+)
Misc Feature(3)273..275(+)
Misc Feature(4)279..281(+)
Misc Feature(5)360..362(+)
Misc Feature(6)387..389(+)
Misc Feature(7)981..3770(+)
Misc Feature(8)981..1337(+)
Misc Feature(9)1374..1841(+)
Misc Feature(10)1971..2954(+)
Misc Feature(11)3033..3701(+)
Misc Feature(12)3162..3185(+)
Misc Feature(13)3171..3506(+)
Misc Feature(14)3285..3296(+)
Misc Feature(15)3309..3350(+)
Misc Feature(16)3387..3404(+)
Misc Feature(17)3411..3422(+)
Misc Feature(18)3492..3512(+)
Exon (1)1..389
Gene:MSH6
Gene Synonym:
Exon (2)390..2934
Gene:MSH6
Gene Synonym:
Exon (3)2935..3200
Gene:MSH6
Gene Synonym:
Exon (4)3201..3318
Gene:MSH6
Gene Synonym:
Exon (5)3319..3408
Gene:MSH6
Gene Synonym:
Exon (6)3409..3563
Gene:MSH6
Gene Synonym:
Exon (7)3564..3763
Gene:MSH6
Gene Synonym:
Exon (8)3764..3938
Gene:MSH6
Gene Synonym:
Translation
Position Chain Variation Link
35 35 a, g dbSNP:556432240
47 47 c, g dbSNP:577888495
54 54 a, g dbSNP:747206043
56 56 c, t dbSNP:538807235
82 82 a, g dbSNP:553984796
102 102 c, g, t dbSNP:375109921
103 103 c, g dbSNP:755310531
104 104 c, g, t dbSNP:113081858
107 107 c, g, t dbSNP:748339592
115 115 c, g dbSNP:185538282
116 116 c, t dbSNP:747521149
119 119 c, g, t dbSNP:771435695
122 122 a, g dbSNP:748779488
124 124 a, g dbSNP:561326741
127 127 a, g dbSNP:773995995
134 134 c, g dbSNP:761485894
135 135 g, t dbSNP:199913053
136 136 c, t dbSNP:370816858
140 140 a, g dbSNP:760597933
141 141 c, g dbSNP:766407370
142 142 -, ggctgtcg dbSNP:760027265
145 145 c, t dbSNP:565211544
147 147 c, g, t dbSNP:730881822
151 151 g, t dbSNP:374748889
157 157 c, t dbSNP:752887988
162 162 c, t dbSNP:786201042
166 166 c, g dbSNP:532585602
167 167 c, t dbSNP:778036049
168 168 a, c dbSNP:200944853
173 173 g, t dbSNP:757815307
174 174 c, t dbSNP:781670952
176 176 c, t dbSNP:746306598
177 177 a, g dbSNP:41294986
180 180 c, t dbSNP:773861137
182 182 c, g, t dbSNP:786201869
185 185 c, g dbSNP:747802641
186 186 a, c, t dbSNP:587782084
187 187 c, t dbSNP:760603184
188 188 c, g dbSNP:760533525
190 190 a, c, g dbSNP:41294988
195 195 c, t dbSNP:776745497
199 199 c, t dbSNP:759501511
205 205 c, g dbSNP:765459817
209 209 c, t dbSNP:752794296
211 211 a, c, t dbSNP:63750664
214 214 a, g dbSNP:267608025
219 219 a, g dbSNP:730881810
223 223 c, t dbSNP:786201684
225 225 g, t dbSNP:267608026
226 226 c, t dbSNP:35462442
228 228 a, t dbSNP:757622849
233 233 c, g dbSNP:781496151
235 235 c, t dbSNP:750949635
237 237 a, c dbSNP:756589186
239 239 c, g dbSNP:778354962
245 245 c, t dbSNP:370817805
246 246 g, t dbSNP:776859837
247 247 a, g dbSNP:771426932
248 248 a, c, t dbSNP:553046896
249 249 c, g, t dbSNP:730881811
253 253 c, t dbSNP:746624223
254 254 a, c dbSNP:201132087
256 256 c, t dbSNP:776547943
258 258 g, t dbSNP:759589301
259 259 c, t dbSNP:61756469
260 260 c, g, t dbSNP:63750213
261 261 a, g dbSNP:775487116
262 262 c, t dbSNP:763104308
264 264 c, t dbSNP:764009461
266 266 c, t dbSNP:786201700
267 267 a, c, g dbSNP:751838296
268 268 a, c, g dbSNP:1042821
269 269 a, c, g dbSNP:756673077
270 270 c, g dbSNP:754231971
271 271 c, t dbSNP:757957751
272 272 c, g dbSNP:777101467
276 276 c, t dbSNP:34014629
279 279 a, t dbSNP:770678180
280 280 a, c dbSNP:781203386
297 297 a, g, t dbSNP:745642001
298 298 a, c, t dbSNP:775498550
299 299 c, t dbSNP:768803986
300 300 c, t dbSNP:374597395
305 305 c, g dbSNP:762061869
309 309 -, ctgggc dbSNP:767894453
313 313 c, g dbSNP:63751098
321 321 c, g dbSNP:773367009
323 323 -, gggccc dbSNP:786201776
327 327 c, t dbSNP:761033647
330 330 c, t dbSNP:35819209
333 333 -, gc dbSNP:775928689
334 334 c, t dbSNP:572336612
338 338 a, c dbSNP:1042820
339 339 c, t dbSNP:763702846
340 340 a, c dbSNP:587779920
342 342 a, c, g dbSNP:587779921
344 344 g, t dbSNP:786203178
346 346 c, t dbSNP:41294984
349 349 a, c dbSNP:730881812
359 359 a, g dbSNP:757025193
366 366 c, g dbSNP:786201910
375 375 a, g dbSNP:781002816
377 377 a, g dbSNP:786202321
379 379 c, t dbSNP:587780672
381 381 c, t dbSNP:745442468
391 391 c, t dbSNP:201431515
393 393 a, g dbSNP:786204153
403 403 a, c dbSNP:773111311
404 404 a, c, g, t dbSNP:1800937
405 405 a, c, g dbSNP:145959653
406 406 g, t dbSNP:587779946
409 409 c, t dbSNP:765195534
410 410 ag, tt dbSNP:63750471
411 411 -, t dbSNP:267607692
412 412 a, g dbSNP:554012110
413 413 -, t dbSNP:63750955
414 414 a, t dbSNP:587779315
418 418 a, g dbSNP:763060788
421 421 a, c, g dbSNP:764478569
422 422 a, c dbSNP:1800938
423 423 a, g dbSNP:757817018
425 425 a, c, g dbSNP:41557217
427 427 a, g dbSNP:750827951
429 429 a, g dbSNP:374041375
430 430 a, g dbSNP:587779316
437 437 a, t dbSNP:572317219
439 439 a, g dbSNP:587781777
440 440 c, g dbSNP:778236337
441 441 a, g dbSNP:786202905
442 442 a, g, t dbSNP:587779317
444 444 a, g dbSNP:587779947
448 448 a, g dbSNP:587782591
449 449 a, g dbSNP:758120391
456 456 c, t dbSNP:587779318
458 458 a, g dbSNP:777770119
460 460 c, g dbSNP:142949377
464 464 -, t dbSNP:730881826
468 468 c, t dbSNP:63750996
472 472 -, g dbSNP:587779319
475 475 a, c dbSNP:587782510
480 480 a, c, t dbSNP:63750019
481 481 a, g dbSNP:542848931
483 483 a, c dbSNP:769962086
489 489 a, c, t dbSNP:377216828
490 490 a, g dbSNP:370157832
492 492 c, t dbSNP:267608066
494 494 a, g dbSNP:774496371
495 495 a, t dbSNP:762168786
500 500 -, t dbSNP:587779320
501 501 -, t dbSNP:63750733
501 501 a, c dbSNP:767828930
503 503 -, a dbSNP:267608041
504 504 a, c, g, t dbSNP:63749980
504 504 -, c dbSNP:587781691
505 505 a, c, g dbSNP:764870249
508 508 g, t dbSNP:752135996
509 509 a, g dbSNP:63750372
511 511 c, t dbSNP:587781275
513 513 a, g dbSNP:554884560
515 515 a, g dbSNP:587779321
516 516 g, t dbSNP:746623981
517 517 c, g dbSNP:267608048
521 521 c, t dbSNP:757143365
524 524 -, tg dbSNP:267608072
534 534 a, g dbSNP:786202565
536 536 -, tgg dbSNP:766451925
556 556 g, t dbSNP:63749890
566 566 c, t dbSNP:780831590
568 568 c, g dbSNP:587779322
571 571 a, t dbSNP:200898010
575 575 -, gga dbSNP:786203409
576 576 g, t dbSNP:63750552
579 579 a, g dbSNP:587779948
580 580 a, g, t dbSNP:769610487
581 581 a, g dbSNP:775693145
583 583 a, g dbSNP:587779949
584 584 c, t dbSNP:768654339
586 586 c, g dbSNP:774586054
593 593 a, c dbSNP:374486449
596 596 a, c dbSNP:368523339
602 602 c, t dbSNP:767974147
604 604 g, t dbSNP:773445382
605 605 -, ac dbSNP:752540976
607 607 -, ggg, t dbSNP:267608062
608 608 c, g dbSNP:573638836
616 616 g, t dbSNP:63750878
623 623 c, t dbSNP:754307139
628 628 aa, gc dbSNP:267608079
628 628 a, c, g dbSNP:368318845
629 629 a, c dbSNP:267608047
631 631 c, t dbSNP:751309721
637 637 g, t dbSNP:587781389
639 639 c, t dbSNP:756935130
645 645 a, g dbSNP:373958499
646 646 a, g, t dbSNP:267608051
654 654 c, t dbSNP:146816935
655 655 a, g dbSNP:765237563
659 659 g, t dbSNP:755878786
660 660 c, t dbSNP:779858670
661 661 a, c, g, t dbSNP:55760494
667 667 a, c, g dbSNP:587781510
671 671 g, t dbSNP:786201688
680 680 a, g dbSNP:748436287
684 684 a, g dbSNP:370174372
688 688 a, c, g, t dbSNP:544222338
689 689 c, t dbSNP:771288794
691 691 c, t dbSNP:777302246
695 695 a, t dbSNP:730881785
700 700 a, g dbSNP:753373644
703 703 a, g dbSNP:760100983
704 704 c, g dbSNP:150440246
706 706 c, g, t dbSNP:63750491
707 707 c, t dbSNP:761581941
709 709 a, g dbSNP:562487553
710 710 a, g dbSNP:750023646
717 717 a, g dbSNP:532920165
718 718 c, t dbSNP:188252826
719 719 a, c, g dbSNP:375210430
720 720 a, c dbSNP:754879198
721 721 c, t dbSNP:779022657
722 722 c, t dbSNP:575325950
726 726 a, g dbSNP:772126419
730 730 c, t dbSNP:777890307
737 737 a, g dbSNP:193922345
739 739 c, t dbSNP:587779323
740 740 a, t dbSNP:747207959
741 741 a, g dbSNP:730881814
742 742 c, g dbSNP:369568820
746 746 c, g, t dbSNP:138143769
750 750 c, t dbSNP:770408023
751 751 a, c dbSNP:786202848
757 757 a, c dbSNP:776080024
760 760 c, t dbSNP:587781983
765 765 a, c dbSNP:761231126
767 767 c, t dbSNP:767011067
769 769 c, g dbSNP:587782102
777 777 c, g dbSNP:772760681
778 778 c, g dbSNP:587780669
781 781 c, t dbSNP:61753793
784 784 c, g dbSNP:766202031
787 787 c, t dbSNP:753617680
790 790 c, g, t dbSNP:548898238
792 792 c, g dbSNP:730881815
797 797 a, t dbSNP:765166082
799 799 c, g, t dbSNP:567785169
805 805 c, t dbSNP:758432113
806 806 a, c dbSNP:587779202
811 811 c, t dbSNP:587782331
812 812 c, t dbSNP:730881802
813 813 c, t dbSNP:587779911
814 814 a, g dbSNP:730881786
815 815 c, t dbSNP:28903083
816 816 a, g dbSNP:730881787
821 821 -, tggag dbSNP:786202336
823 823 g, t dbSNP:730881788
825 825 a, g dbSNP:587778531
829 829 c, g dbSNP:776170146
830 830 c, t dbSNP:749752524
831 831 a, g dbSNP:771529531
834 834 c, g dbSNP:772747395
836 836 c, g dbSNP:760311819
840 840 a, g dbSNP:145994565
841 841 g, t dbSNP:267608060
843 843 c, t dbSNP:587782651
844 844 a, g dbSNP:63750440
847 847 -, c dbSNP:267608056
847 847 c, t dbSNP:759359754
849 849 a, g dbSNP:764965018
855 855 c, t dbSNP:752628520
856 856 c, g dbSNP:587780558
861 861 a, c dbSNP:201193496
863 863 -, t dbSNP:587779203
868 868 c, t dbSNP:375974046
869 869 -, tt dbSNP:786204252
871 871 c, t dbSNP:587779204
875 875 a, g dbSNP:786203202
882 882 -, aag dbSNP:587781660
884 884 a, g dbSNP:786203929
889 889 a, c, g dbSNP:764150912
891 891 -, aagag dbSNP:777907133
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1255 1255 a, g dbSNP:147136417
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1336 1336 a, g dbSNP:765387680
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1373 1373 a, g dbSNP:786203776
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1394 1394 -, aaaa dbSNP:267608064
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1398 1398 -, gag dbSNP:779537048
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1458 1458 a, g dbSNP:63749973
1459 1459 c, g dbSNP:758990693
1460 1460 a, c dbSNP:764818222
1463 1463 c, g dbSNP:752435825
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1475 1475 g, t dbSNP:781019496
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1532 1532 c, t dbSNP:267608070
1533 1533 c, t dbSNP:267608045
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1598 1598 a, g dbSNP:779035516
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1611 1611 a, c dbSNP:773619924
1615 1615 a, g dbSNP:747576518
1619 1619 a, c dbSNP:63751121
1626 1626 a, c dbSNP:587778529
1628 1628 a, t dbSNP:1042817
1629 1629 c, g dbSNP:3136334
1630 1630 a, c, t dbSNP:63750462
1631 1631 -, c dbSNP:71539659
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1632 1632 -, g dbSNP:777159874
1633 1633 g, t dbSNP:763606858
1636 1636 c, t dbSNP:773927995
1637 1637 a, c, t dbSNP:63749886
1640 1640 a, g dbSNP:767285340
1643 1643 c, t dbSNP:750208909
1656 1656 a, g dbSNP:755847154
1657 1657 a, c dbSNP:750800736
1662 1662 -, tt dbSNP:587782638
1663 1663 -, tg dbSNP:267608082
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1676 1676 c, t dbSNP:766310490
1677 1677 a, g dbSNP:143517321
1679 1679 a, c, g dbSNP:368059229
1680 1680 -, gaa dbSNP:762299881
1683 1683 -, gaa dbSNP:786203970
1694 1694 c, g dbSNP:34938432
1697 1697 a, g dbSNP:779019430
1699 1699 a, g dbSNP:201096652
1700 1700 a, g dbSNP:758631207
1708 1708 a, t dbSNP:777799551
1712 1712 c, t dbSNP:747380250
1713 1713 a, g dbSNP:536562413
1714 1714 c, t dbSNP:144823143
1715 1715 g, t dbSNP:746352186
1719 1719 c, g dbSNP:768095444
1721 1721 g, t dbSNP:773910090
1722 1722 -, gtga dbSNP:63751167
1723 1723 c, t dbSNP:761433489
1724 1724 a, g dbSNP:148592158
1725 1725 a, t dbSNP:786203468
1736 1736 a, g dbSNP:372916347
1756 1756 a, g dbSNP:786201952
1757 1757 c, g dbSNP:587778532
1758 1758 c, t dbSNP:587779222
1759 1759 c, t dbSNP:760494271
1761 1761 c, g dbSNP:151086192
1766 1766 c, g dbSNP:766113887
1767 1767 a, g dbSNP:753812859
1768 1768 c, t dbSNP:555209664
1770 1770 a, g dbSNP:63749857
1775 1775 a, g dbSNP:765289515
1779 1779 c, g dbSNP:377356882
1787 1787 a, c, g dbSNP:587779223
1789 1789 a, g dbSNP:143643688
1792 1792 c, g dbSNP:587779224
1794 1794 c, g dbSNP:751778243
1797 1797 c, t dbSNP:757741943
1798 1798 c, t dbSNP:781668793
1802 1802 c, t dbSNP:746448428
1805 1805 c, t dbSNP:770323844
1807 1807 -, ct dbSNP:267608057
1807 1807 c, g, t dbSNP:587779225
1808 1808 c, t dbSNP:755329012
1810 1810 c, t dbSNP:747699430
1812 1812 c, g dbSNP:771445440
1813 1813 -, ct dbSNP:587779226
1814 1814 a, g dbSNP:772874585
1816 1816 c, g dbSNP:63750358
1817 1817 c, t dbSNP:760299985
1819 1819 a, g dbSNP:587779227
1820 1820 c, t dbSNP:770778638
1823 1823 a, t dbSNP:267608068
1824 1824 -, gt dbSNP:63750075
1831 1831 a, c, t dbSNP:730881794
1832 1832 c, t dbSNP:559125434
1833 1833 c, t dbSNP:765224443
1836 1836 a, c dbSNP:752532578
1841 1841 -, a dbSNP:267608083
1842 1842 c, t dbSNP:587779228
1849 1849 c, t dbSNP:587779229
1854 1854 a, c, g dbSNP:63750832
1860 1860 c, t dbSNP:587779230
1865 1865 a, g dbSNP:764244124
1867 1867 c, g, t dbSNP:63751419
1869 1869 a, g dbSNP:751867550
1873 1873 c, g dbSNP:370237509
1879 1879 c, t dbSNP:587779231
1886 1886 a, g dbSNP:781730324
1887 1887 -, t dbSNP:587781650
1889 1889 a, t dbSNP:587779232
1891 1891 c, t dbSNP:750817344
1896 1896 c, t dbSNP:780570825
1897 1897 c, t dbSNP:371414784
1900 1900 a, g dbSNP:730881795
1903 1903 c, g, t dbSNP:730881796
1904 1904 c, t dbSNP:786201606
1906 1906 -, ac dbSNP:786204048
1908 1908 a, g dbSNP:749711246
1909 1909 -, cagt dbSNP:587782275
1909 1909 c, t dbSNP:587782805
1912 1912 -, tcag dbSNP:267608058
1916 1916 c, t dbSNP:771662801
1918 1918 c, t dbSNP:373418713
1921 1921 c, t dbSNP:185531778
1923 1923 a, g dbSNP:537604099
1925 1925 a, t dbSNP:770584242
1927 1927 -, ctggtgctatcttcaccaaag dbSNP:63749941
1927 1927 a, c dbSNP:776198410
1930 1930 c, g dbSNP:759403696
1931 1931 c, t dbSNP:769422122
1933 1933 c, g, t dbSNP:587779922
1935 1935 a, g dbSNP:148898662
1937 1937 c, g dbSNP:63750304
1938 1938 ag, tt dbSNP:63750136
1939 1939 a, t dbSNP:574358605
1941 1941 a, g dbSNP:761930694
1942 1942 a, c, g dbSNP:767861096
1945 1945 a, c, g dbSNP:35552856
1949 1949 a, c, t dbSNP:375610656
1951 1951 a, g dbSNP:587782900
1953 1953 c, t dbSNP:63751442
1956 1956 a, c, t dbSNP:63751127
1957 1957 a, c, g dbSNP:749746725
1962 1962 a, g dbSNP:587780671
1965 1965 a, c dbSNP:786204071
1973 1973 a, g dbSNP:780916013
1981 1981 a, t dbSNP:745483465
1985 1985 c, t dbSNP:769668640
1988 1988 c, g dbSNP:587781739
1989 1989 c, t dbSNP:749308906
1990 1990 -, g dbSNP:773290953
1992 1992 -, g dbSNP:786201050
1995 1995 a, g dbSNP:768731337
1997 1997 g, t dbSNP:556339046
2001 2001 c, t dbSNP:63751305
2003 2003 a, g dbSNP:377722465
2011 2011 a, c dbSNP:730881817
2015 2015 c, t dbSNP:2020913
2018 2018 c, t dbSNP:786202129
2020 2020 -, cta dbSNP:762872662
2022 2022 a, c dbSNP:545057945
2024 2024 a, c, t dbSNP:553076837
2030 2030 a, c, g dbSNP:142246608
2033 2033 c, g, t dbSNP:142172006
2034 2034 c, t dbSNP:56371757
2043 2043 a, g dbSNP:199876321
2044 2044 a, c, g dbSNP:587779233
2051 2051 c, t dbSNP:137946937
2053 2053 a, c, t dbSNP:561198849
2057 2057 c, g, t dbSNP:63750985
2060 2060 g, t dbSNP:768535330
2061 2061 a, t dbSNP:774452933
2062 2062 c, g, t dbSNP:587781462
2064 2064 -, cct dbSNP:63750647
2064 2064 c, g dbSNP:35946687
2065 2065 a, c dbSNP:773162893
2071 2071 a, g dbSNP:587781478
2076 2076 a, c, t dbSNP:63750138
2077 2077 a, g dbSNP:63750725
2081 2081 a, c, t dbSNP:63749895
2085 2085 a, c dbSNP:759915781
2091 2091 a, t dbSNP:267608067
2092 2092 a, g dbSNP:587779234
2101 2101 c, g, t dbSNP:63749899
2103 2103 a, c, t dbSNP:587779235
2108 2108 c, t dbSNP:753238686
2109 2109 a, t dbSNP:373721483
2110 2110 -, gt dbSNP:267608065
2118 2118 c, t dbSNP:773193199
2122 2122 c, t dbSNP:63750637
2124 2124 a, g dbSNP:587778530
2133 2133 c, t dbSNP:749918474
2134 2134 a, g dbSNP:755587950
2135 2135 c, t dbSNP:543201797
2137 2137 c, t dbSNP:587779236
2141 2141 -, tg dbSNP:587779237
2146 2146 c, t dbSNP:202127474
2149 2149 a, g dbSNP:532445704
2151 2151 -, g dbSNP:63751095
2153 2153 c, t dbSNP:754870044
2154 2154 c, g dbSNP:587779238
2160 2160 a, c, g dbSNP:61748083
2161 2161 c, t dbSNP:63750895
2162 2162 c, t dbSNP:267608071
2170 2170 a, g dbSNP:63751450
2174 2174 a, g dbSNP:201460265
2179 2179 c, g dbSNP:372990379
2180 2180 c, t dbSNP:770992427
2181 2181 a, c, g dbSNP:587779923
2186 2186 g, t dbSNP:770208363
2187 2187 -, g dbSNP:63751053
2188 2188 -, tag dbSNP:587779240
2188 2188 -, ttaatgtc dbSNP:766653592
2188 2188 c, t dbSNP:775815297
2190 2190 c, g dbSNP:763248984
2191 2191 a, t dbSNP:764516652
2205 2205 a, c, t dbSNP:377411318
2206 2206 g, t dbSNP:760129709
2214 2214 c, g dbSNP:786203612
2229 2229 a, g dbSNP:267608032
2238 2238 c, g dbSNP:765891603
2243 2243 c, t dbSNP:753585861
2244 2244 a, g dbSNP:587781349
2245 2245 c, t dbSNP:754675891
2253 2253 c, g dbSNP:267608053
2255 2255 c, t dbSNP:778911612
2263 2263 a, g dbSNP:752544046
2265 2265 c, t dbSNP:63751321
2270 2270 c, t dbSNP:758170249
2271 2271 c, t dbSNP:777593472
2273 2273 c, g dbSNP:587779925
2275 2275 c, t dbSNP:770952730
2282 2282 c, t dbSNP:781241667
2286 2286 c, g dbSNP:746143003
2288 2288 g, t dbSNP:772394197
2294 2294 a, g dbSNP:786201873
2297 2297 -, t dbSNP:587779241
2301 2301 a, g dbSNP:775625082
2302 2302 a, g dbSNP:749648487
2309 2309 a, g dbSNP:769018957
2311 2311 a, g dbSNP:63750389
2312 2312 a, c, t dbSNP:374230313
2313 2313 a, g dbSNP:762352116
2316 2316 -, aag dbSNP:751683437
2321 2321 a, g dbSNP:765873566
2323 2323 -, aga dbSNP:587782858
2323 2323 ag, tt dbSNP:587780673
2323 2323 a, t dbSNP:34374438
2324 2324 g, t dbSNP:759048538
2326 2326 -, t dbSNP:760558287
2328 2328 a, t dbSNP:765012437
2331 2331 -, gatt dbSNP:587779243
2331 2331 a, g dbSNP:368437140
2332 2332 a, g dbSNP:758176077
2341 2341 c, t dbSNP:370412074
2342 2342 c, t dbSNP:751515279
2353 2353 a, g dbSNP:587781306
2357 2357 a, c dbSNP:757202837
2359 2359 a, c dbSNP:190075874
2361 2361 a, g dbSNP:745954217
2362 2362 g, t dbSNP:139598980
2365 2365 c, t dbSNP:780280765
2366 2366 a, g dbSNP:749508276
2367 2367 c, t dbSNP:768941857
2376 2376 -, atta dbSNP:63750357
2386 2386 c, t dbSNP:774774596
2390 2390 a, g dbSNP:748663356
2391 2391 a, g dbSNP:730881797
2395 2395 c, g, t dbSNP:2020912
2402 2402 a, c, t dbSNP:371399245
2403 2403 aaaa, g dbSNP:63751408
2410 2410 a, c dbSNP:764816440
2413 2413 c, g dbSNP:561217424
2415 2415 a, t dbSNP:587782593
2418 2418 a, g dbSNP:2020914
2420 2420 c, t dbSNP:786201051
2423 2423 g, t dbSNP:267608069
2426 2426 c, g dbSNP:730881798
2428 2428 a, c dbSNP:377542011
2429 2429 g, t dbSNP:149945495
2430 2430 c, g dbSNP:786202628
2433 2433 a, g dbSNP:756933423
2434 2434 c, tct dbSNP:587779244
2435 2435 c, g, t dbSNP:146006741
2436 2436 -, t dbSNP:63750982
2439 2439 c, g, t dbSNP:370754319
2444 2444 a, g dbSNP:756239543
2446 2446 c, g dbSNP:780081278
2447 2447 a, t dbSNP:749539614
2452 2452 a, g dbSNP:755215367
2456 2456 c, t dbSNP:769668106
2457 2457 a, g dbSNP:748574765
2462 2462 a, t dbSNP:1042816
2463 2463 a, c, t dbSNP:772514245
2464 2464 a, g dbSNP:63749889
2468 2468 c, t dbSNP:778472296
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3718 3718 -, aagc dbSNP:267608119
3719 3719 -, tcaaaagggacatagaaaa dbSNP:63750767
3720 3720 -, gcaa dbSNP:267608123
3720 3720 g, t dbSNP:376300764
3721 3721 -, caag dbSNP:267608120
3722 3722 a, g dbSNP:373425206
3723 3723 a, g dbSNP:41295278
3725 3725 a, t dbSNP:267608125
3727 3727 a, t dbSNP:763608368
3731 3731 -, tgagaagatga dbSNP:587779299
3732 3732 c, g dbSNP:540890590
3734 3734 c, g dbSNP:587779938
3736 3736 -, aga dbSNP:587779300
3738 3738 a, c, t dbSNP:587779939
3739 3739 c, t dbSNP:757089977
3740 3740 -, aatc dbSNP:786204180
3740 3740 a, c, g dbSNP:141464646
3741 3741 -, a dbSNP:587782326
3741 3741 a, c dbSNP:756216566
3742 3742 -, tcag dbSNP:751033488
3742 3742 a, g dbSNP:780187989
3745 3745 -, atca dbSNP:786201855
3745 3745 a, g dbSNP:587779940
3746 3746 -, atca dbSNP:267608124
3748 3748 c, t dbSNP:199594809
3749 3749 -, gtca dbSNP:267608121
3750 3750 c, t dbSNP:768944975
3751 3751 g, t dbSNP:774395829
3753 3753 c, t dbSNP:267608094
3754 3754 g, t dbSNP:184131049
3755 3755 a, g dbSNP:772401158
3756 3756 a, t dbSNP:786204160
3762 3762 -, atttc dbSNP:587779301
3762 3762 c, t dbSNP:773763465
3763 3763 a, g dbSNP:267608122
3766 3766 a, c dbSNP:564434147
3767 3767 a, c dbSNP:786204130
3768 3768 a, g dbSNP:771181616
3771 3771 -, tgcc dbSNP:759779793
3773 3773 c, t dbSNP:139825189
3776 3776 c, g dbSNP:61748086
3778 3778 c, g dbSNP:528399386
3784 3784 a, g dbSNP:770359323
3787 3787 c, g dbSNP:774012741
3789 3789 -, caa dbSNP:772655560
3795 3795 a, g dbSNP:747613376
3798 3798 a, g dbSNP:374649126
3801 3801 c, g dbSNP:730881809
3806 3806 a, c dbSNP:786203740
3810 3810 c, g dbSNP:772707858
3816 3816 a, c dbSNP:587782309
3820 3820 g, t dbSNP:56238300
3821 3821 -, ctga dbSNP:775836476
3823 3823 a, c, t dbSNP:267608140
3826 3826 -, gtca dbSNP:267608141
3827 3827 g, t dbSNP:766073664
3830 3830 -, gatt dbSNP:587781301
3830 3830 a, c, g dbSNP:192740549
3831 3831 -, ttga dbSNP:267608142
3833 3833 -, gatt dbSNP:587779311
3834 3834 a, g dbSNP:199739099
3836 3836 -, taag dbSNP:386833407
3836 3836 g, t dbSNP:759392159
3837 3837 -, aatt dbSNP:575068534
3837 3837 a, g, t dbSNP:267608081
3842 3842 -, atagactgactacattggaagctt dbSNP:587781746
3842 3842 -, atta dbSNP:587782547
3843 3843 c, t dbSNP:765098678
3844 3844 -, gact dbSNP:762031413
3845 3845 -, gact dbSNP:765313977
3846 3846 a, g dbSNP:587781604
3847 3847 c, t dbSNP:752809310
3848 3848 -, tgactacat dbSNP:766605075
3848 3848 c, t dbSNP:786203308
3851 3851 c, t dbSNP:758445380
3854 3854 c, t dbSNP:371301277
3855 3855 a, c dbSNP:757778351
3856 3856 c, t dbSNP:757708396
3861 3861 a, g dbSNP:374743162
3864 3864 -, ttgag dbSNP:754683604
3865 3865 -, ttgag dbSNP:751404750
3867 3867 -, agtt dbSNP:781241504
3868 3868 a, g dbSNP:200412142
3869 3869 -, gttga dbSNP:587779200
3871 3871 c, t dbSNP:756712244
3878 3878 -, gaca dbSNP:752652467
3878 3878 c, t dbSNP:568272054
3879 3879 a, c, g dbSNP:184571812
3881 3881 -, a dbSNP:755754032
3881 3881 a, c dbSNP:771683883
3882 3882 a, g dbSNP:368491299
3894 3894 c, t dbSNP:772973603
3896 3896 a, c dbSNP:746634080
3902 3902 a, t dbSNP:551144193
3907 3907 a, g dbSNP:569367018
3923 3923 -, tt dbSNP:587779201
3929 3929 a, t dbSNP:267608143
3930 3930 a, t dbSNP:2020906

Target ORF information:

RefSeq Version NM_001281492
Organism Homo sapiens (human)
Definition Homo sapiens mutS homolog 6 (MSH6), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001281492

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
3481
3541
3601
3661
ATGTCGCGAC AGAGCACCCT GTACAGCTTC TTCCCCAAGT CTCCGGCGCT GAGTGATGCC 
AACAAGGCCT CGGCCAGGGC CTCACGCGAA GGCGGCCGTG CCGCCGCTGC CCCCGGGGCC
TCTCCTTCCC CAGGCGGGGA TGCGGCCTGG AGCGAGGCTG GGCCTGGGCC CAGGCCCTTG
GCGCGCTCCG CGTCACCGCC CAAGGCGAAG AACCTCAACG GAGGGCTGCG GAGATCGGTA
GGCACAACTT ACGTAACAGA TAAGAGTGAA GAAGATAATG AAATTGAGAG TGAAGAGGAA
GTACAGCCTA AGACACAAGG ATCTAGGCGA AGTAGCCGCC AAATAAAAAA ACGAAGGGTC
ATATCAGATT CTGAGAGTGA CATTGGTGGC TCTGATGTGG AATTTAAGCC AGACACTAAG
GAGGAAGGAA GCAGTGATGA AATAAGCAGT GGAGTGGGGG ATAGTGAGAG TGAAGGCCTG
AACAGCCCTG TCAAAGTTGC TCGAAAGCGG AAGAGAATGG TGACTGGAAA TGGCTCTCTT
AAAAGGAAAA GCTCTAGGAA GGAAACGCCC TCAGCCACCA AACAAGCAAC TAGCATTTCA
TCAGAAACCA AGAATACTTT GAGAGCTTTC TCTGCCCCTC AAAATTCTGA ATCCCAAGCC
CACGTTAGTG GAGGTGGTGA TGACAGTAGT CGCCCTACTG TTTGGTATCA TGAAACTTTA
GAATGGCTTA AGGAGGAAAA GAGAAGAGAT GAGCACAGGA GGAGGCCTGA TCACCCCGAT
TTTGATGCAT CTACACTCTA TGTGCCTGAG GATTTCCTCA ATTCTTGTAC TCCTGGGATG
AGGAAGTGGT GGCAGATTAA GTCTCAGAAC TTTGATCTTG TCATCTGTTA CAAGGTGGGG
AAATTTTATG AGCTGTACCA CATGGATGCT CTTATTGGAG TCAGTGAACT GGGGCTGGTA
TTCATGAAAG GCAACTGGGC CCATTCTGGC TTTCCTGAAA TTGCATTTGG CCGTTATTCA
GATTCCCTGG TGCAGAAGGG CTATAAAGTA GCACGAGTGG AACAGACTGA GACTCCAGAA
ATGATGGAGG CACGATGTAG AAAGATGGCA CATATATCCA AGTATGATAG AGTGGTGAGG
AGGGAGATCT GTAGGATCAT TACCAAGGGT ACACAGACTT ACAGTGTGCT GGAAGGTGAT
CCCTCTGAGA ACTACAGTAA GTATCTTCTT AGCCTCAAAG AAAAAGAGGA AGATTCTTCT
GGCCATACTC GTGCATATGG TGTGTGCTTT GTTGATACTT CACTGGGAAA GTTTTTCATA
GGTCAGTTTT CAGATGATCG CCATTGTTCG AGATTTAGGA CTCTAGTGGC ACACTATCCC
CCAGTACAAG TTTTATTTGA AAAAGGAAAT CTCTCAAAGG AAACTAAAAC AATTCTAAAG
AGTTCATTGT CCTGTTCTCT TCAGGAAGGT CTGATACCCG GCTCCCAGTT TTGGGATGCA
TCCAAAACTT TGAGAACTCT CCTTGAGGAA GAATATTTTA GGGAAAAGCT AAGTGATGGC
ATTGGGGTGA TGTTACCCCA GGTGCTTAAA GGTATGACTT CAGAGTCTGA TTCCATTGGG
TTGACACCAG GAGAGAAAAG TGAATTGGCC CTCTCTGCTC TAGGTGGTTG TGTCTTCTAC
CTCAAAAAAT GCCTTATTGA TCAGGAGCTT TTATCAATGG CTAATTTTGA AGAATATATT
CCCTTGGATT CTGACACAGT CAGCACTACA AGATCTGGTG CTATCTTCAC CAAAGCCTAT
CAACGAATGG TGCTAGATGC AGTGACATTA AACAACTTGG AGATTTTTCT GAATGGAACA
AATGGTTCTA CTGAAGGAAC CCTACTAGAG AGGGTTGATA CTTGCCATAC TCCTTTTGGT
AAGCGGCTCC TAAAGCAATG GCTTTGTGCC CCACTCTGTA ACCATTATGC TATTAATGAT
CGTCTAGATG CCATAGAAGA CCTCATGGTT GTGCCTGACA AAATCTCCGA AGTTGTAGAG
CTTCTAAAGA AGCTTCCAGA TCTTGAGAGG CTACTCAGTA AAATTCATAA TGTTGGGTCT
CCCCTGAAGA GTCAGAACCA CCCAGACAGC AGGGCTATAA TGTATGAAGA AACTACATAC
AGCAAGAAGA AGATTATTGA TTTTCTTTCT GCTCTGGAAG GATTCAAAGT AATGTGTAAA
ATTATAGGGA TCATGGAAGA AGTTGCTGAT GGTTTTAAGT CTAAAATCCT TAAGCAGGTC
ATCTCTCTGC AGACAAAAAA TCCTGAAGGT CGTTTTCCTG ATTTGACTGT AGAATTGAAC
CGATGGGATA CAGCCTTTGA CCATGAAAAG GCTCGAAAGA CTGGACTTAT TACTCCCAAA
GCAGGCTTTG ACTCTGATTA TGACCAAGCT CTTGCTGACA TAAGAGAAAA TGAACAGAGC
CTCCTGGAAT ACCTAGAGAA ACAGCGCAAC AGAATTGGCT GTAGGACCAT AGTCTATTGG
GGGATTGGTA GGAACCGTTA CCAGCTGGAA ATTCCTGAGA ATTTCACCAC TCGCAATTTG
CCAGAAGAAT ACGAGTTGAA ATCTACCAAG AAGGGCTGTA AACGATACTG GACCAAAACT
ATTGAAAAGA AGTTGGCTAA TCTCATAAAT GCTGAAGAAC GGAGGGATGT ATCATTGAAG
GACTGCATGC GGCGACTGTT CTATAACTTT GATAAAAATT ACAAGGACTG GCAGTCTGCT
GTAGAGTGTA TCGCAGTGTT GGATGTTTTA CTGTGCCTGG CTAACTATAG TCGAGGGGGT
GATGGTCCTA TGTGTCGCCC AGTAATTCTG TTGCCGGAAG ATACCCCCCC CTTCTTAGAG
CTTAAAGGAT CACGCCATCC TTGCATTACG AAGACTTTTT TTGGAGATGA TTTTATTCCT
AATGACATTC TAATAGGCTG TGAGGAAGAG GAGCAGGAAA ATGGCAAAGC CTATTGTGTG
CTTGTTACTG GACCAAATAT GGGGGGCAAG TCTACGCTTA TGAGACAGGC TGGCTTATTA
GCTGTAATGG CCCAGATGGG TTGTTACGTC CCTGCTGAAG TGTGCAGGCT CACACCAATT
GATAGAGTGT TTACTAGACT TGGTGCCTCA GACAGAATAA TGTCAGGTGA AAGTACATTT
TTTGTTGAAT TAAGTGAAAC TGCCAGCATA CTCATGCATG CAACAGCACA TTCTCTGGTG
CTTGTGGATG AATTAGGAAG AGGTACTGCA ACATTTGATG GGACGGCAAT AGCAAATGCA
GTTGTTAAAG AACTTGCTGA GACTATAAAA TGTCGTACAT TATTTTCAAC TCACTACCAT
TCATTAGTAG AAGATTATTC TCAAAATGTT GCTGTGCGCC TAGGACATAT GGCATGCATG
GTAGAAAATG AATGTGAAGA CCCCAGCCAG GAGACTATTA CGTTCCTCTA TAAATTCATT
AAGGGAGCTT GTCCTAAAAG CTATGGCTTT AATGCAGCAA GGCTTGCTAA TCTCCCAGAG
GAAGTTATTC AAAAGGGACA TAGAAAAGCA AGAGAATTTG AGAAGATGAA TCAGTCACTA
CGATTATTTC GGGAAGTTTG CCTGGCTAGT GAAAGGTCAA CTGTAGATGC TGAAGCTGTC
CATAAATTGC TGACTTTGAT TAAGGAATTA TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu58146
Accession Version XM_011532798.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 3900bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector Document: User manual_GenEZ ORF Clone Products.pdf (pdf)
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags Document: MSDS_GenEZ ORF Clone Products.pdf (pdf)
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product DNA mismatch repair protein Msh6 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_022184.16) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
3481
3541
3601
3661
3721
3781
3841
ATGCCTGCGG GAGGCCGAAC GGGGAGAGTC CGGTGGTGTG GGGTGCGAAA GGAGGTTCCT 
CGGCCGGCGC GGAGATATTG TGACTTCTCA CCAGGAGATT TGGTTTGGGC CAAGATGGAG
GGTTACCCCT GGTGGCCTTG TCTGGTTTAC AACCACCCCT TTGATGGAAC ATTCATCCGC
GAGAAAGGGA AATCAGTCCG TGTTCATGTA CAGTTTTTTG ATGACAGCCC AACAAGGGGC
TGGGTTAGCA AAAGGCTTTT AAAGCCATAT ACAGGTTCAA AATCAAAGGA AGCCCAGAAG
GGAGGTCATT TTTACAGTGC AAAGCCTGAA ATACTGAGAG CAATGCAACG TGCAGATGAA
GCCTTAAATA AAGACAAGAT TAAGAGGCTT GAATTGGCAG TTTGTGATGA GCCCTCAGAG
CCAGAAGAGG AAGAAGAGAT GGAGGTAGGC ACAACTTACG TAACAGATAA GAGTGAAGAA
GATAATGAAA TTGAGAGTGA AGAGGAAGTA CAGCCTAAGA CACAAGGATC TAGGCGAAGT
AGCCGCCAAA TAAAAAAACG AAGGGTCATA TCAGATTCTG AGAGTGACAT TGGTGGCTCT
GATGTGGAAT TTAAGCCAGA CACTAAGGAG GAAGGAAGCA GTGATGAAAT AAGCAGTGGA
GTGGGGGATA GTGAGAGTGA AGGCCTGAAC AGCCCTGTCA AAGTTGCTCG AAAGCGGAAG
AGAATGGTGA CTGGAAATGG CTCTCTTAAA AGGAAAAGCT CTAGGAAGGA AACGCCCTCA
GCCACCAAAC AAGCAACTAG CATTTCATCA GAAACCAAGA ATACTTTGAG AGCTTTCTCT
GCCCCTCAAA ATTCTGAATC CCAAGCCCAC GTTAGTGGAG GTGGTGATGA CAGTAGTCGC
CCTACTGTTT GGTATCATGA AACTTTAGAA TGGCTTAAGG AGGAAAAGAG AAGAGATGAG
CACAGGAGGA GGCCTGATCA CCCCGATTTT GATGCATCTA CACTCTATGT GCCTGAGGAT
TTCCTCAATT CTTGTACTCC TGGGATGAGG AAGTGGTGGC AGATTAAGTC TCAGAACTTT
GATCTTGTCA TCTGTTACAA GGTGGGGAAA TTTTATGAGC TGTACCACAT GGATGCTCTT
ATTGGAGTCA GTGAACTGGG GCTGGTATTC ATGAAAGGCA ACTGGGCCCA TTCTGGCTTT
CCTGAAATTG CATTTGGCCG TTATTCAGAT TCCCTGGTGC AGAAGGGCTA TAAAGTAGCA
CGAGTGGAAC AGACTGAGAC TCCAGAAATG ATGGAGGCAC GATGTAGAAA GATGGCACAT
ATATCCAAGT ATGATAGAGT GGTGAGGAGG GAGATCTGTA GGATCATTAC CAAGGGTACA
CAGACTTACA GTGTGCTGGA AGGTGATCCC TCTGAGAACT ACAGTAAGTA TCTTCTTAGC
CTCAAAGAAA AAGAGGAAGA TTCTTCTGGC CATACTCGTG CATATGGTGT GTGCTTTGTT
GATACTTCAC TGGGAAAGTT TTTCATAGGT CAGTTTTCAG ATGATCGCCA TTGTTCGAGA
TTTAGGACTC TAGTGGCACA CTATCCCCCA GTACAAGTTT TATTTGAAAA AGGAAATCTC
TCAAAGGAAA CTAAAACAAT TCTAAAGAGT TCATTGTCCT GTTCTCTTCA GGAAGGTCTG
ATACCCGGCT CCCAGTTTTG GGATGCATCC AAAACTTTGA GAACTCTCCT TGAGGAAGAA
TATTTTAGGG AAAAGCTAAG TGATGGCATT GGGGTGATGT TACCCCAGGT GCTTAAAGGT
ATGACTTCAG AGTCTGATTC CATTGGGTTG ACACCAGGAG AGAAAAGTGA ATTGGCCCTC
TCTGCTCTAG GTGGTTGTGT CTTCTACCTC AAAAAATGCC TTATTGATCA GGAGCTTTTA
TCAATGGCTA ATTTTGAAGA ATATATTCCC TTGGATTCTG ACACAGTCAG CACTACAAGA
TCTGGTGCTA TCTTCACCAA AGCCTATCAA CGAATGGTGC TAGATGCAGT GACATTAAAC
AACTTGGAGA TTTTTCTGAA TGGAACAAAT GGTTCTACTG AAGGAACCCT ACTAGAGAGG
GTTGATACTT GCCATACTCC TTTTGGTAAG CGGCTCCTAA AGCAATGGCT TTGTGCCCCA
CTCTGTAACC ATTATGCTAT TAATGATCGT CTAGATGCCA TAGAAGACCT CATGGTTGTG
CCTGACAAAA TCTCCGAAGT TGTAGAGCTT CTAAAGAAGC TTCCAGATCT TGAGAGGCTA
CTCAGTAAAA TTCATAATGT TGGGTCTCCC CTGAAGAGTC AGAACCACCC AGACAGCAGG
GCTATAATGT ATGAAGAAAC TACATACAGC AAGAAGAAGA TTATTGATTT TCTTTCTGCT
CTGGAAGGAT TCAAAGTAAT GTGTAAAATT ATAGGGATCA TGGAAGAAGT TGCTGATGGT
TTTAAGTCTA AAATCCTTAA GCAGGTCATC TCTCTGCAGA CAAAAAATCC TGAAGGTCGT
TTTCCTGATT TGACTGTAGA ATTGAACCGA TGGGATACAG CCTTTGACCA TGAAAAGGCT
CGAAAGACTG GACTTATTAC TCCCAAAGCA GGCTTTGACT CTGATTATGA CCAAGCTCTT
GCTGACATAA GAGAAAATGA ACAGAGCCTC CTGGAATACC TAGAGAAACA GCGCAACAGA
ATTGGCTGTA GGACCATAGT CTATTGGGGG ATTGGTAGGA ACCGTTACCA GCTGGAAATT
CCTGAGAATT TCACCACTCG CAATTTGCCA GAAGAATACG AGTTGAAATC TACCAAGAAG
GGCTGTAAAC GATACTGGAC CAAAACTATT GAAAAGAAGT TGGCTAATCT CATAAATGCT
GAAGAACGGA GGGATGTATC ATTGAAGGAC TGCATGCGGC GACTGTTCTA TAACTTTGAT
AAAAATTACA AGGACTGGCA GTCTGCTGTA GAGTGTATCG CAGTGTTGGA TGTTTTACTG
TGCCTGGCTA ACTATAGTCG AGGGGGTGAT GGTCCTATGT GTCGCCCAGT AATTCTGTTG
CCGGAAGATA CCCCCCCCTT CTTAGAGCTT AAAGGATCAC GCCATCCTTG CATTACGAAG
ACTTTTTTTG GAGATGATTT TATTCCTAAT GACATTCTAA TAGGCTGTGA GGAAGAGGAG
CAGGAAAATG GCAAAGCCTA TTGTGTGCTT GTTACTGGAC CAAATATGGG GGGCAAGTCT
ACGCTTATGA GACAGGCTGG CTTATTAGCT GTAATGGCCC AGATGGGTTG TTACGTCCCT
GCTGAAGTGT GCAGGCTCAC ACCAATTGAT AGAGTGTTTA CTAGACTTGG TGCCTCAGAC
AGAATAATGT CAGGTGAAAG TACATTTTTT GTTGAATTAA GTGAAACTGC CAGCATACTC
ATGCATGCAA CAGCACATTC TCTGGTGCTT GTGGATGAAT TAGGAAGAGG TACTGCAACA
TTTGATGGGA CGGCAATAGC AAATGCAGTT GTTAAAGAAC TTGCTGAGAC TATAAAATGT
CGTACATTAT TTTCAACTCA CTACCATTCA TTAGTAGAAG ATTATTCTCA AAATGTTGCT
GTGCGCCTAG GACATATGGC ATGCATGGTA GAAAATGAAT GTGAAGACCC CAGCCAGGAG
ACTATTACGT TCCTCTATAA ATTCATTAAG GGAGCTTGTC CTAAAAGCTA TGGCTTTAAT
GCAGCAAGGC TTGCTAATCT CCCAGAGGAA GTTATTCAAA AGGGACATAG AAAAGCAAGA
GAATTTGAGA AGATGAATCA GTCACTACGA TTATTTCGGG AAGTTTGCCT GGCTAGTGAA
AGGTCAACTG TAGATGCTGA AGCTGTCCAT AAATTGCTGA CTTTGATTAA GGAATTATAG
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqXP_011531100.1
CDS43..3942
Misc Feature(1)121..444(+)
Misc Feature(2)157..276(+)
Misc Feature(3)1078..3867(+)
Misc Feature(4)1078..1434(+)
Misc Feature(5)1471..1938(+)
Misc Feature(6)2068..3051(+)
Misc Feature(7)3130..3798(+)
Misc Feature(8)3259..3282(+)
Misc Feature(9)3268..3603(+)
Misc Feature(10)3382..3393(+)
Misc Feature(11)3406..3447(+)
Misc Feature(12)3484..3501(+)
Misc Feature(13)3508..3519(+)
Misc Feature(14)3589..3609(+)
Translation
Position Chain Variation Link
14 14 c, g dbSNP:62139911
21 21 -, ggcgggg dbSNP:60717693
23 23 -, c dbSNP:3136234
28 28 g, t dbSNP:527428575
32 32 a, g dbSNP:3136235
34 34 a, g dbSNP:3136236
65 65 c, g dbSNP:3136237
84 84 c, g dbSNP:531348092
86 86 g, t dbSNP:367630365
95 95 a, g dbSNP:549751558
106 106 a, c dbSNP:142624180
126 126 c, g, t dbSNP:762818044
135 135 a, g dbSNP:1800932
142 142 g, t dbSNP:786202397
149 149 c, g dbSNP:752680756
156 156 g, t dbSNP:63751258
166 166 c, t dbSNP:758303780
167 167 a, t dbSNP:777900107
180 180 c, t dbSNP:730881823
192 192 c, t dbSNP:786202772
194 194 a, g dbSNP:587779934
203 203 c, t dbSNP:781271765
212 212 a, c dbSNP:746060136
213 213 a, g dbSNP:558590898
217 217 a, g dbSNP:146455343
218 218 c, t dbSNP:775971872
220 220 c, t dbSNP:763593669
221 221 a, g dbSNP:769279475
222 222 c, t dbSNP:587779276
223 223 a, g dbSNP:143036974
225 225 a, c, g dbSNP:774303198
228 228 a, t dbSNP:587782106
229 229 c, g dbSNP:786203479
232 232 a, g dbSNP:372352774
242 242 g, t dbSNP:63750143
243 243 -, t dbSNP:63750374
250 250 c, g dbSNP:765060096
252 252 a, c dbSNP:752488540
253 253 c, g dbSNP:587782101
254 254 a, c dbSNP:587779298
256 256 -, ttttttgatgacag dbSNP:786202193
276 276 a, g dbSNP:758390144
282 282 c, g, t dbSNP:777587467
285 285 a, g dbSNP:63750342
290 290 g, t dbSNP:3211299
299 299 a, t dbSNP:63750525
307 307 c, t dbSNP:587782406
308 308 c, g dbSNP:757311007
326 326 c, g dbSNP:63749873
327 327 -, aaag dbSNP:587779941
330 330 a, g dbSNP:786202690
335 335 c, t dbSNP:587778528
339 339 g, t dbSNP:786203645
342 342 a, g dbSNP:63751030
346 346 a, g dbSNP:776065389
348 348 g, t dbSNP:745399921
349 349 c, t dbSNP:568685193
350 350 a, c, t dbSNP:146469162
353 353 g, t dbSNP:763841886
357 357 c, t dbSNP:587779313
362 362 c, g dbSNP:774162322
364 364 a, g dbSNP:761721805
366 366 c, g dbSNP:767474992
372 372 a, g dbSNP:786201116
374 374 c, t dbSNP:587779942
381 381 -, ag dbSNP:267608037
381 381 a, g dbSNP:779496213
385 385 a, g dbSNP:750327994
391 391 c, t dbSNP:730881813
392 392 a, g dbSNP:786204186
394 394 g, t dbSNP:587781817
399 399 c, t dbSNP:1800935
400 400 a, g dbSNP:569728764
411 411 c, t dbSNP:786203679
412 412 a, g dbSNP:193922344
417 417 c, g, t dbSNP:587779943
424 424 a, t dbSNP:786203597
434 434 a, c, t dbSNP:375757570
436 436 g, t dbSNP:587779944
436 436 -, t dbSNP:587782281
437 437 -, t dbSNP:786201043
442 442 g, t dbSNP:267608038
446 446 g, t dbSNP:78939940
448 448 c, g dbSNP:148517241
455 455 c, t dbSNP:587782315
458 458 a, c dbSNP:63751077
459 459 -, ag dbSNP:730881824
461 461 -, ag dbSNP:587779945
462 462 a, g dbSNP:587779314
464 464 c, g dbSNP:367644746
468 468 a, g dbSNP:536686679
477 477 a, g dbSNP:758635514
481 481 a, g dbSNP:369058374
484 484 g, t dbSNP:747477669
486 486 a, g dbSNP:769312569
488 488 c, t dbSNP:201431515
490 490 a, g dbSNP:786204153
500 500 a, c dbSNP:773111311
501 501 a, c, g, t dbSNP:1800937
502 502 a, c, g dbSNP:145959653
503 503 g, t dbSNP:587779946
506 506 c, t dbSNP:765195534
507 507 ag, tt dbSNP:63750471
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1929 1929 c, t dbSNP:559125434
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