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GYS1 cDNA ORF clone, Homo sapiens (human)

Gene Symbol GYS1
Entrez Gene ID 2997
Full Name glycogen synthase 1 (muscle)
Synonyms GSY, GYS
General protein information
Preferred Names
glycogen [starch] synthase, muscle
Names
glycogen [starch] synthase, muscle
NP_001155059.1
NP_002094.2
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

19

19q13.3

Summary The protein encoded by this gene catalyzes the addition of glucose monomers to the growing glycogen molecule through the formation of alpha-1,4-glycoside linkages. Mutations in this gene are associated with muscle glycogen storage disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]. lac of sum
Disorder MIM:

138570

Disorder Html: Glycogen storage disease 0, muscle, 611556 (3)

mRNA and Protein(s)

mRNA Protein Name
NM_002103 NP_002094 glycogen [starch] synthase, muscle isoform 1
NM_001161587 NP_001155059 glycogen [starch] synthase, muscle isoform 2



Homo sapiens (human) GYS1 NP_002094.2
Pan troglodytes (chimpanzee) GYS1 XP_003316534.1
Macaca mulatta (Rhesus monkey) GYS1 NP_001028058.1
Canis lupus familiaris (dog) GYS1 XP_854809.3
Bos taurus (cattle) GYS1 NP_001094769.1
Mus musculus (house mouse) Gys1 NP_109603.2
Rattus norvegicus (Norway rat) Gys1 NP_001103085.1
Danio rerio (zebrafish) gys1 NP_957474.1
Drosophila melanogaster (fruit fly) CG6904 NP_731967.2
Caenorhabditis elegans gsy-1 NP_496736.1
Xenopus (Silurana) tropicalis (western clawed frog) LOC100490155 XP_004916359.1


GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following GYS1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GYS1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu19222 NM_002103 Homo sapiens glycogen synthase 1 (muscle) (GYS1), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $265.30
$379.00
OHu14737
NM_001161587 Homo sapiens glycogen synthase 1 (muscle) (GYS1), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$189.50-$265.30
$379.00
Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
5 or more Clone 50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu19222
Clone ID Related Accession (Same CDS sequence) NM_002103
Accession Version NM_002103.4 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2214bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product glycogen [starch] synthase, muscle isoform 1
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP313940.1 and BC002617.2. This sequence is a reference standard in the RefSeqGene project. On Jun 6, 2009 this sequence version replaced gi:34222292. Transcript Variant: This variant (1) encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC002617.2, J04501.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
ATGCCTTTAA ACCGCACTTT GTCCATGTCC TCACTGCCAG GACTGGAGGA CTGGGAGGAT 
GAATTCGACC TGGAGAACGC AGTGCTCTTC GAAGTGGCCT GGGAGGTGGC TAACAAGGTG
GGTGGCATCT ACACGGTGCT GCAGACGAAG GCGAAGGTGA CAGGGGACGA ATGGGGCGAC
AACTACTTCC TGGTGGGGCC GTACACGGAG CAGGGCGTGA GGACCCAGGT GGAACTGCTG
GAGGCCCCCA CCCCGGCCCT GAAGAGGACA CTGGATTCCA TGAACAGCAA GGGCTGCAAG
GTGTATTTCG GGCGCTGGCT GATCGAGGGA GGCCCTCTGG TGGTGCTCCT GGACGTGGGT
GCCTCAGCTT GGGCCCTGGA GCGCTGGAAG GGAGAGCTCT GGGATACCTG CAACATCGGA
GTGCCGTGGT ACGACCGCGA GGCCAACGAC GCTGTCCTCT TTGGCTTTCT GACCACCTGG
TTCCTGGGTG AGTTCCTGGC ACAGAGTGAG GAGAAGCCAC ATGTGGTTGC TCACTTCCAT
GAGTGGTTGG CAGGCGTTGG ACTCTGCCTG TGTCGTGCCC GGCGACTGCC TGTAGCAACC
ATCTTCACCA CCCATGCCAC GCTGCTGGGG CGCTACCTGT GTGCCGGTGC CGTGGACTTC
TACAACAACC TGGAGAACTT CAACGTGGAC AAGGAAGCAG GGGAGAGGCA GATCTACCAC
CGATACTGCA TGGAAAGGGC GGCAGCCCAC TGCGCTCACG TCTTCACTAC TGTGTCCCAG
ATCACCGCCA TCGAGGCACA GCACTTGCTC AAGAGGAAAC CAGATATTGT GACCCCCAAT
GGGCTGAATG TGAAGAAGTT TTCTGCCATG CATGAGTTCC AGAACCTCCA TGCTCAGAGC
AAGGCTCGAA TCCAGGAGTT TGTGCGGGGC CATTTTTATG GGCATCTGGA CTTCAACTTG
GACAAGACCT TATACTTCTT TATCGCCGGC CGCTATGAGT TCTCCAACAA GGGTGCTGAC
GTCTTCCTGG AGGCATTGGC TCGGCTCAAC TATCTGCTCA GAGTGAACGG CAGCGAGCAG
ACAGTGGTTG CCTTCTTCAT CATGCCAGCG CGGACCAACA ATTTCAACGT GGAAACCCTC
AAAGGCCAAG CTGTGCGCAA ACAGCTTTGG GACACGGCCA ACACGGTGAA GGAAAAGTTC
GGGAGGAAGC TTTATGAATC CTTACTGGTT GGGAGCCTTC CCGACATGAA CAAGATGCTG
GATAAGGAAG ACTTCACTAT GATGAAGAGA GCCATCTTTG CAACGCAGCG GCAGTCTTTC
CCCCCTGTGT GCACCCACAA TATGCTGGAT GACTCCTCAG ACCCCATCCT GACCACCATC
CGCCGAATCG GCCTCTTCAA TAGCAGTGCC GACAGGGTGA AGGTGATTTT CCACCCGGAG
TTCCTCTCCT CCACAAGCCC CCTGCTCCCT GTGGACTATG AGGAGTTTGT CCGTGGCTGT
CACCTTGGAG TCTTCCCCTC CTACTATGAG CCTTGGGGCT ACACACCGGC TGAGTGCACG
GTTATGGGAA TCCCCAGTAT CTCCACCAAT CTCTCCGGCT TCGGCTGCTT CATGGAGGAA
CACATCGCAG ACCCCTCAGC TTACGGTATC TACATTCTTG ACCGGCGGTT CCGCAGCCTG
GATGATTCCT GCTCGCAGCT CACCTCCTTC CTCTACAGTT TCTGTCAGCA GAGCCGGCGG
CAGCGTATCA TCCAGCGGAA CCGCACGGAG CGCCTCTCCG ACCTTCTGGA CTGGAAATAC
CTAGGCCGGT ACTATATGTC TGCGCGCCAC ATGGCGCTGT CCAAGGCCTT TCCAGAGCAC
TTCACCTACG AGCCCAACGA GGCGGATGCG GCCCAGGGGT ACCGCTACCC ACGGCCAGCC
TCGGTGCCAC CGTCGCCCTC GCTGTCACGA CACTCCAGCC CGCACCAGAG TGAGGACGAG
GAGGATCCCC GGAACGGGCC GCTGGAGGAA GACGGCGAGC GCTACGATGA GGACGAGGAG
GCCGCCAAGG ACCGGCGCAA CATCCGTGCA CCAGAGTGGC CGCGCCGAGC GTCCTGCACC
TCCTCCACCA GCGGCAGCAA GCGCAACTCT GTGGACACGG CCACCTCCAG CTCACTCAGC
ACCCCGAGCG AGCCCCTCAG CCCCACCAGC TCCCTGGGCG AGGAGCGTAA CTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_002094.2
CDS242..2455
Misc Feature(1)47..49(+)
Misc Feature(2)263..265(+)
Misc Feature(3)269..271(+)
Misc Feature(4)317..2086(+)
Misc Feature(5)332..2230(+)
Misc Feature(6)2162..2164(+)
Misc Feature(7)2162..2164(+)
Misc Feature(8)2174..2176(+)
Misc Feature(9)2174..2176(+)
Misc Feature(10)2180..2182(+)
Misc Feature(11)2186..2188(+)
Misc Feature(12)2186..2188(+)
Misc Feature(13)2195..2197(+)
Misc Feature(14)2198..2200(+)
Misc Feature(15)2198..2200(+)
Misc Feature(16)2333..2335(+)
Misc Feature(17)2342..2344(+)
Misc Feature(18)2369..2371(+)
Misc Feature(19)2378..2380(+)
Misc Feature(20)2384..2386(+)
Misc Feature(21)2387..2389(+)
Misc Feature(22)2390..2392(+)
Misc Feature(23)2393..2395(+)
Misc Feature(24)2399..2401(+)
Misc Feature(25)2420..2422(+)
Misc Feature(26)2420..2422(+)
Misc Feature(27)2426..2428(+)
Misc Feature(28)2429..2431(+)
Misc Feature(29)2432..2434(+)
Exon (1)1..359
Gene:GYS1
Gene Synonym:
Exon (2)360..541
Gene:GYS1
Gene Synonym:
Exon (3)542..733
Gene:GYS1
Gene Synonym:
Exon (4)734..919
Gene:GYS1
Gene Synonym:
Exon (5)920..1064
Gene:GYS1
Gene Synonym:
Exon (6)1065..1182
Gene:GYS1
Gene Synonym:
Exon (7)1183..1303
Gene:GYS1
Gene Synonym:
Exon (8)1304..1410
Gene:GYS1
Gene Synonym:
Exon (9)1411..1470
Gene:GYS1
Gene Synonym:
Exon (10)1471..1549
Gene:GYS1
Gene Synonym:
Exon (11)1550..1663
Gene:GYS1
Gene Synonym:
Exon (12)1664..1790
Gene:GYS1
Gene Synonym:
Exon (13)1791..1886
Gene:GYS1
Gene Synonym:
Exon (14)1887..2050
Gene:GYS1
Gene Synonym:
Exon (15)2051..2131
Gene:GYS1
Gene Synonym:
Exon (16)2132..3618
Gene:GYS1
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_002103
Organism Homo sapiens (human)
Definition Homo sapiens glycogen synthase 1 (muscle) (GYS1), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_002103

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
ATGCCTTTAA ACCGCACTTT GTCCATGTCC TCACTGCCAG GACTGGAGGA CTGGGAGGAT 
GAATTCGACC TGGAGAACGC AGTGCTCTTC GAAGTGGCCT GGGAGGTGGC TAACAAGGTG
GGTGGCATCT ACACGGTGCT GCAGACGAAG GCGAAGGTGA CAGGGGACGA ATGGGGCGAC
AACTACTTCC TGGTGGGGCC GTACACGGAG CAGGGCGTGA GGACCCAGGT GGAACTGCTG
GAGGCCCCCA CCCCGGCCCT GAAGAGGACA CTGGATTCCA TGAACAGCAA GGGCTGCAAG
GTGTATTTCG GGCGCTGGCT GATCGAGGGA GGCCCTCTGG TGGTGCTCCT GGACGTGGGT
GCCTCAGCTT GGGCCCTGGA GCGCTGGAAG GGAGAGCTCT GGGATACCTG CAACATCGGA
GTGCCGTGGT ACGACCGCGA GGCCAACGAC GCTGTCCTCT TTGGCTTTCT GACCACCTGG
TTCCTGGGTG AGTTCCTGGC ACAGAGTGAG GAGAAGCCAC ATGTGGTTGC TCACTTCCAT
GAGTGGTTGG CAGGCGTTGG ACTCTGCCTG TGTCGTGCCC GGCGACTGCC TGTAGCAACC
ATCTTCACCA CCCATGCCAC GCTGCTGGGG CGCTACCTGT GTGCCGGTGC CGTGGACTTC
TACAACAACC TGGAGAACTT CAACGTGGAC AAGGAAGCAG GGGAGAGGCA GATCTACCAC
CGATACTGCA TGGAAAGGGC GGCAGCCCAC TGCGCTCACG TCTTCACTAC TGTGTCCCAG
ATCACCGCCA TCGAGGCACA GCACTTGCTC AAGAGGAAAC CAGATATTGT GACCCCCAAT
GGGCTGAATG TGAAGAAGTT TTCTGCCATG CATGAGTTCC AGAACCTCCA TGCTCAGAGC
AAGGCTCGAA TCCAGGAGTT TGTGCGGGGC CATTTTTATG GGCATCTGGA CTTCAACTTG
GACAAGACCT TATACTTCTT TATCGCCGGC CGCTATGAGT TCTCCAACAA GGGTGCTGAC
GTCTTCCTGG AGGCATTGGC TCGGCTCAAC TATCTGCTCA GAGTGAACGG CAGCGAGCAG
ACAGTGGTTG CCTTCTTCAT CATGCCAGCG CGGACCAACA ATTTCAACGT GGAAACCCTC
AAAGGCCAAG CTGTGCGCAA ACAGCTTTGG GACACGGCCA ACACGGTGAA GGAAAAGTTC
GGGAGGAAGC TTTATGAATC CTTACTGGTT GGGAGCCTTC CCGACATGAA CAAGATGCTG
GATAAGGAAG ACTTCACTAT GATGAAGAGA GCCATCTTTG CAACGCAGCG GCAGTCTTTC
CCCCCTGTGT GCACCCACAA TATGCTGGAT GACTCCTCAG ACCCCATCCT GACCACCATC
CGCCGAATCG GCCTCTTCAA TAGCAGTGCC GACAGGGTGA AGGTGATTTT CCACCCGGAG
TTCCTCTCCT CCACAAGCCC CCTGCTCCCT GTGGACTATG AGGAGTTTGT CCGTGGCTGT
CACCTTGGAG TCTTCCCCTC CTACTATGAG CCTTGGGGCT ACACACCGGC TGAGTGCACG
GTTATGGGAA TCCCCAGTAT CTCCACCAAT CTCTCCGGCT TCGGCTGCTT CATGGAGGAA
CACATCGCAG ACCCCTCAGC TTACGGTATC TACATTCTTG ACCGGCGGTT CCGCAGCCTG
GATGATTCCT GCTCGCAGCT CACCTCCTTC CTCTACAGTT TCTGTCAGCA GAGCCGGCGG
CAGCGTATCA TCCAGCGGAA CCGCACGGAG CGCCTCTCCG ACCTTCTGGA CTGGAAATAC
CTAGGCCGGT ACTATATGTC TGCGCGCCAC ATGGCGCTGT CCAAGGCCTT TCCAGAGCAC
TTCACCTACG AGCCCAACGA GGCGGATGCG GCCCAGGGGT ACCGCTACCC ACGGCCAGCC
TCGGTGCCAC CGTCGCCCTC GCTGTCACGA CACTCCAGCC CGCACCAGAG TGAGGACGAG
GAGGATCCCC GGAACGGGCC GCTGGAGGAA GACGGCGAGC GCTACGATGA GGACGAGGAG
GCCGCCAAGG ACCGGCGCAA CATCCGTGCA CCAGAGTGGC CGCGCCGAGC GTCCTGCACC
TCCTCCACCA GCGGCAGCAA GCGCAACTCT GTGGACACGG CCACCTCCAG CTCACTCAGC
ACCCCGAGCG AGCCCCTCAG CCCCACCAGC TCCCTGGGCG AGGAGCGTAA CTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu14737
Clone ID Related Accession (Same CDS sequence) NM_001161587
Accession Version NM_001161587.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2022bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product glycogen [starch] synthase, muscle isoform 2
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP313940.1, BC003182.1 and BC002617.2. Transcript Variant: This variant (2) is missing an in-frame coding exon at the 3' end compared to variant 1, resulting in a shorter isoform (2) lacking an internal protein segment compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC003182.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
ATGCCTTTAA ACCGCACTTT GTCCATGTCC TCACTGCCAG GACTGGAGGA CTGGGAGGAT 
GAATTCGACC TGGAGAACGC AGTGCTCTTC GAAGTGGCCT GGGAGGTGGC TAACAAGGTG
GGTGGCATCT ACACGGTGCT GCAGACGAAG GCGAAGGTGA CAGGGGACGA ATGGGGCGAC
AACTACTTCC TGGTGGGGCC GTACACGGAG CAGGGCGTGA GGACCCAGGT GGAACTGCTG
GAGGCCCCCA CCCCGGCCCT GAAGAGGACA CTGGATTCCA TGAACAGCAA GGGCTGCAAG
TTCCTGGCAC AGAGTGAGGA GAAGCCACAT GTGGTTGCTC ACTTCCATGA GTGGTTGGCA
GGCGTTGGAC TCTGCCTGTG TCGTGCCCGG CGACTGCCTG TAGCAACCAT CTTCACCACC
CATGCCACGC TGCTGGGGCG CTACCTGTGT GCCGGTGCCG TGGACTTCTA CAACAACCTG
GAGAACTTCA ACGTGGACAA GGAAGCAGGG GAGAGGCAGA TCTACCACCG ATACTGCATG
GAAAGGGCGG CAGCCCACTG CGCTCACGTC TTCACTACTG TGTCCCAGAT CACCGCCATC
GAGGCACAGC ACTTGCTCAA GAGGAAACCA GATATTGTGA CCCCCAATGG GCTGAATGTG
AAGAAGTTTT CTGCCATGCA TGAGTTCCAG AACCTCCATG CTCAGAGCAA GGCTCGAATC
CAGGAGTTTG TGCGGGGCCA TTTTTATGGG CATCTGGACT TCAACTTGGA CAAGACCTTA
TACTTCTTTA TCGCCGGCCG CTATGAGTTC TCCAACAAGG GTGCTGACGT CTTCCTGGAG
GCATTGGCTC GGCTCAACTA TCTGCTCAGA GTGAACGGCA GCGAGCAGAC AGTGGTTGCC
TTCTTCATCA TGCCAGCGCG GACCAACAAT TTCAACGTGG AAACCCTCAA AGGCCAAGCT
GTGCGCAAAC AGCTTTGGGA CACGGCCAAC ACGGTGAAGG AAAAGTTCGG GAGGAAGCTT
TATGAATCCT TACTGGTTGG GAGCCTTCCC GACATGAACA AGATGCTGGA TAAGGAAGAC
TTCACTATGA TGAAGAGAGC CATCTTTGCA ACGCAGCGGC AGTCTTTCCC CCCTGTGTGC
ACCCACAATA TGCTGGATGA CTCCTCAGAC CCCATCCTGA CCACCATCCG CCGAATCGGC
CTCTTCAATA GCAGTGCCGA CAGGGTGAAG GTGATTTTCC ACCCGGAGTT CCTCTCCTCC
ACAAGCCCCC TGCTCCCTGT GGACTATGAG GAGTTTGTCC GTGGCTGTCA CCTTGGAGTC
TTCCCCTCCT ACTATGAGCC TTGGGGCTAC ACACCGGCTG AGTGCACGGT TATGGGAATC
CCCAGTATCT CCACCAATCT CTCCGGCTTC GGCTGCTTCA TGGAGGAACA CATCGCAGAC
CCCTCAGCTT ACGGTATCTA CATTCTTGAC CGGCGGTTCC GCAGCCTGGA TGATTCCTGC
TCGCAGCTCA CCTCCTTCCT CTACAGTTTC TGTCAGCAGA GCCGGCGGCA GCGTATCATC
CAGCGGAACC GCACGGAGCG CCTCTCCGAC CTTCTGGACT GGAAATACCT AGGCCGGTAC
TATATGTCTG CGCGCCACAT GGCGCTGTCC AAGGCCTTTC CAGAGCACTT CACCTACGAG
CCCAACGAGG CGGATGCGGC CCAGGGGTAC CGCTACCCAC GGCCAGCCTC GGTGCCACCG
TCGCCCTCGC TGTCACGACA CTCCAGCCCG CACCAGAGTG AGGACGAGGA GGATCCCCGG
AACGGGCCGC TGGAGGAAGA CGGCGAGCGC TACGATGAGG ACGAGGAGGC CGCCAAGGAC
CGGCGCAACA TCCGTGCACC AGAGTGGCCG CGCCGAGCGT CCTGCACCTC CTCCACCAGC
GGCAGCAAGC GCAACTCTGT GGACACGGCC ACCTCCAGCT CACTCAGCAC CCCGAGCGAG
CCCCTCAGCC CCACCAGCTC CCTGGGCGAG GAGCGTAACT AA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001155059.1
CDS242..2263
Misc Feature(1)47..49(+)
Misc Feature(2)317..1894(+)
Misc Feature(3)332..2038(+)
Exon (1)1..359
Gene:GYS1
Gene Synonym:
Exon (2)360..541
Gene:GYS1
Gene Synonym:
Exon (3)542..727
Gene:GYS1
Gene Synonym:
Exon (4)728..872
Gene:GYS1
Gene Synonym:
Exon (5)873..990
Gene:GYS1
Gene Synonym:
Exon (6)991..1111
Gene:GYS1
Gene Synonym:
Exon (7)1112..1218
Gene:GYS1
Gene Synonym:
Exon (8)1219..1278
Gene:GYS1
Gene Synonym:
Exon (9)1279..1357
Gene:GYS1
Gene Synonym:
Exon (10)1358..1471
Gene:GYS1
Gene Synonym:
Exon (11)1472..1598
Gene:GYS1
Gene Synonym:
Exon (12)1599..1694
Gene:GYS1
Gene Synonym:
Exon (13)1695..1858
Gene:GYS1
Gene Synonym:
Exon (14)1859..1939
Gene:GYS1
Gene Synonym:
Exon (15)1940..3426
Gene:GYS1
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001161587
Organism Homo sapiens (human)
Definition Homo sapiens glycogen synthase 1 (muscle) (GYS1), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001161587

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
ATGCCTTTAA ACCGCACTTT GTCCATGTCC TCACTGCCAG GACTGGAGGA CTGGGAGGAT 
GAATTCGACC TGGAGAACGC AGTGCTCTTC GAAGTGGCCT GGGAGGTGGC TAACAAGGTG
GGTGGCATCT ACACGGTGCT GCAGACGAAG GCGAAGGTGA CAGGGGACGA ATGGGGCGAC
AACTACTTCC TGGTGGGGCC GTACACGGAG CAGGGCGTGA GGACCCAGGT GGAACTGCTG
GAGGCCCCCA CCCCGGCCCT GAAGAGGACA CTGGATTCCA TGAACAGCAA GGGCTGCAAG
TTCCTGGCAC AGAGTGAGGA GAAGCCACAT GTGGTTGCTC ACTTCCATGA GTGGTTGGCA
GGCGTTGGAC TCTGCCTGTG TCGTGCCCGG CGACTGCCTG TAGCAACCAT CTTCACCACC
CATGCCACGC TGCTGGGGCG CTACCTGTGT GCCGGTGCCG TGGACTTCTA CAACAACCTG
GAGAACTTCA ACGTGGACAA GGAAGCAGGG GAGAGGCAGA TCTACCACCG ATACTGCATG
GAAAGGGCGG CAGCCCACTG CGCTCACGTC TTCACTACTG TGTCCCAGAT CACCGCCATC
GAGGCACAGC ACTTGCTCAA GAGGAAACCA GATATTGTGA CCCCCAATGG GCTGAATGTG
AAGAAGTTTT CTGCCATGCA TGAGTTCCAG AACCTCCATG CTCAGAGCAA GGCTCGAATC
CAGGAGTTTG TGCGGGGCCA TTTTTATGGG CATCTGGACT TCAACTTGGA CAAGACCTTA
TACTTCTTTA TCGCCGGCCG CTATGAGTTC TCCAACAAGG GTGCTGACGT CTTCCTGGAG
GCATTGGCTC GGCTCAACTA TCTGCTCAGA GTGAACGGCA GCGAGCAGAC AGTGGTTGCC
TTCTTCATCA TGCCAGCGCG GACCAACAAT TTCAACGTGG AAACCCTCAA AGGCCAAGCT
GTGCGCAAAC AGCTTTGGGA CACGGCCAAC ACGGTGAAGG AAAAGTTCGG GAGGAAGCTT
TATGAATCCT TACTGGTTGG GAGCCTTCCC GACATGAACA AGATGCTGGA TAAGGAAGAC
TTCACTATGA TGAAGAGAGC CATCTTTGCA ACGCAGCGGC AGTCTTTCCC CCCTGTGTGC
ACCCACAATA TGCTGGATGA CTCCTCAGAC CCCATCCTGA CCACCATCCG CCGAATCGGC
CTCTTCAATA GCAGTGCCGA CAGGGTGAAG GTGATTTTCC ACCCGGAGTT CCTCTCCTCC
ACAAGCCCCC TGCTCCCTGT GGACTATGAG GAGTTTGTCC GTGGCTGTCA CCTTGGAGTC
TTCCCCTCCT ACTATGAGCC TTGGGGCTAC ACACCGGCTG AGTGCACGGT TATGGGAATC
CCCAGTATCT CCACCAATCT CTCCGGCTTC GGCTGCTTCA TGGAGGAACA CATCGCAGAC
CCCTCAGCTT ACGGTATCTA CATTCTTGAC CGGCGGTTCC GCAGCCTGGA TGATTCCTGC
TCGCAGCTCA CCTCCTTCCT CTACAGTTTC TGTCAGCAGA GCCGGCGGCA GCGTATCATC
CAGCGGAACC GCACGGAGCG CCTCTCCGAC CTTCTGGACT GGAAATACCT AGGCCGGTAC
TATATGTCTG CGCGCCACAT GGCGCTGTCC AAGGCCTTTC CAGAGCACTT CACCTACGAG
CCCAACGAGG CGGATGCGGC CCAGGGGTAC CGCTACCCAC GGCCAGCCTC GGTGCCACCG
TCGCCCTCGC TGTCACGACA CTCCAGCCCG CACCAGAGTG AGGACGAGGA GGATCCCCGG
AACGGGCCGC TGGAGGAAGA CGGCGAGCGC TACGATGAGG ACGAGGAGGC CGCCAAGGAC
CGGCGCAACA TCCGTGCACC AGAGTGGCCG CGCCGAGCGT CCTGCACCTC CTCCACCAGC
GGCAGCAAGC GCAACTCTGT GGACACGGCC ACCTCCAGCT CACTCAGCAC CCCGAGCGAG
CCCCTCAGCC CCACCAGCTC CCTGGGCGAG GAGCGTAACT AA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

Genome-wide association study of sex hormones, gonadotropins and sex hormone-binding protein in Chinese men
J. Med. Genet. 50 (12), 794-801 (2013)
Chen Z, Tao S, Gao Y, Zhang J, Hu Y, Mo L, Kim ST, Yang X, Tan A, Zhang H, Qin X, Li L, Wu Y, Zhang S, Zheng SL, Xu J, Mo Z and Sun J.


book

Akt2 influences glycogen synthase activity in human skeletal muscle through regulation of NH(2)-terminal (sites 2 + 2a) phosphorylation
Am. J. Physiol. Endocrinol. Metab. 304 (6), E631-E639 (2013)
Friedrichsen M, Birk JB, Richter EA, Ribel-Madsen R, Pehmoller C, Hansen BF, Beck-Nielsen H, Hirshman MF, Goodyear LJ, Vaag A, Poulsen P and Wojtaszewski JF.


book

Regulation of glycogen synthase from mammalian skeletal muscle--a unifying view of allosteric and covalent regulation
FEBS J. 280 (1), 2-27 (2013)
Palm DC, Rohwer JM and Hofmeyr JH.


book

GLUT4 and glycogen synthase are key players in bed rest-induced insulin resistance
Diabetes 61 (5), 1090-1099 (2012)
Bienso RS, Ringholm S, Kiilerich K, Aachmann-Andersen NJ, Krogh-Madsen R, Guerra B, Plomgaard P, van Hall G, Treebak JT, Saltin B, Lundby C, Calbet JA, Pilegaard H and Wojtaszewski JF.


book

Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study
Diabetes Care 33 (10), 2250-2253 (2010)
Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC and Anand S.


book

Isolation and characterization of the human muscle glycogen synthase gene
Diabetes 44 (9), 1099-1105 (1995)
Orho M, Nikula-Ijas P, Schalin-Jantti C, Permutt MA and Groop LC.


book

Increased concentrations of glycogen synthase protein in skeletal muscle of patients with NIDDM
Am. J. Physiol. 269 (1 PT 1), E27-E32 (1995)
Lofman M, Yki-Jarvinen H, Parkkonen M, Lindstrom J, Koranyi L, Schalin-Jantti C and Groop L.


book

Phosphate groups as substrate determinants for casein kinase I action
J. Biol. Chem. 265 (24), 14264-14269 (1990)
Flotow H, Graves PR, Wang AQ, Fiol CJ, Roeske RW and Roach PJ.


book

Human muscle glycogen synthase cDNA sequence: a negatively charged protein with an asymmetric charge distribution
Proc. Natl. Acad. Sci. U.S.A. 86 (5), 1443-1447 (1989)
Browner MF, Nakano K, Bang AG and Fletterick RJ.


book

Glycogen synthase from rabbit skeletal muscle. Amino acid sequence at the sites phosphorylated by glycogen synthase kinase-3, and extension of the N-terminal sequence containing the site phosphorylated by phosphorylase kinase
Eur. J. Biochem. 107 (2), 529-537 (1980)
Rylatt,D.B., Aitken,A., Bilham,T., Condon,G.D., Embi,N. and Cohen,P.


 
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