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HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 [Homo sapiens (human)]

Gene Symbol HLA-DQB1
Entrez Gene ID 3119
Full Name major histocompatibility complex, class II, DQ beta 1
Synonyms CELIAC1, HLA-DQB, IDDM1
General protein information
Preferred Names
HLA class II histocompatibility antigen, DQ beta 1 chain
Names
HLA class II histocompatibility antigen, DQ beta 1 chain
MHC DQ beta
MHC class2 antigen
lymphocyte antigen
MHC class II antigen DQB1
MHC class II DQ beta chain
MHC class II antigen HLA-DQ-beta-1
MHC class II HLA-DQ beta glycoprotein
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

6

6p21.3

Summary HLA-DQB1 belongs to the HLA class II beta chain paralogs. This class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and it contains six exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to four different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011]. lac of sum
Disorder MIM:

604305

Disorder Html: {Creutzfeldt-Jakob disease, variant, resistance to}, 123400 (3);





The following HLA-DQB1 gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the HLA-DQB1 gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu29135 NM_001243962 Homo sapiens major histocompatibility complex, class II, DQ beta 1 (HLA-DQB1), transcript variant 3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$139.3
$199
OHu26742 NM_002123 Homo sapiens major histocompatibility complex, class II, DQ beta 1 (HLA-DQB1), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $269
OHu20771 NM_001243961 Homo sapiens major histocompatibility complex, class II, DQ beta 1 (HLA-DQB1), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $199

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu29135
Accession Version NM_001243962.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 786bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 18-JAN-2014
Organism Homo sapiens (human)
Product HLA class II histocompatibility antigen, DQ beta 1 chain isoform 1 precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL731683.12. This sequence is a reference standard in the RefSeqGene project. On or before Jul 26, 2012 this sequence version replaced gi:397140063, gi:397140065. Summary: HLA-DQB1 belongs to the HLA class II beta chain paralogs. This class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and it contains six exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to four different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011]. Transcript Variant: This variant (3) has the same exon combination as variant 1 but represents the DQB1*02:01:01:01 allele of the HLA-DQB1 gene, as represented in the alternate locus group ALT_REF_LOCI_2 of the reference genome. It encodes isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK296613.1, X03068.1 [ECO:0000332] RNAseq introns :: single sample supports all introns ERS025082, ERS025091 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGTCTTGGA AAAAGGCTTT GCGGATCCCC GGAGGCCTTC GGGCAGCAAC TGTGACCTTG 
ATGCTGTCGA TGCTGAGCAC CCCAGTGGCT GAGGGCAGAG ACTCTCCCGA GGATTTCGTG
TACCAGTTTA AGGGCATGTG CTACTTCACC AACGGGACAG AGCGCGTGCG TCTTGTGAGC
AGAAGCATCT ATAACCGAGA AGAGATCGTG CGCTTCGACA GCGACGTGGG GGAGTTCCGG
GCGGTGACGC TGCTGGGGCT GCCTGCCGCC GAGTACTGGA ACAGCCAGAA GGACATCCTG
GAGAGGAAAC GGGCGGCGGT GGACAGGGTG TGCAGACACA ACTACCAGTT GGAGCTCCGC
ACGACCTTGC AGCGGCGAGT GGAGCCCACA GTGACCATCT CCCCATCCAG GACAGAGGCC
CTCAACCACC ACAACCTGCT GGTCTGCTCG GTGACAGATT TCTATCCAGC CCAGATCAAA
GTCCGGTGGT TTCGGAATGA CCAGGAGGAG ACAGCTGGCG TTGTGTCCAC CCCCCTTATT
AGGAATGGTG ACTGGACCTT CCAGATCCTG GTGATGCTGG AAATGACTCC CCAGCGTGGA
GACGTCTACA CCTGCCACGT GGAGCACCCC AGCCTCCAGA GCCCCATCAC CGTGGAGTGG
CGGGCTCAAT CTGAATCTGC CCAGAGCAAG ATGCTGAGTG GCATTGGAGG CTTCGTGCTG
GGGCTGATCT TCCTCGGGCT GGGCCTTATC ATCCATCACA GGAGTCAGAA AGGGCTCCTG
CACTGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_001230891.1
CDS80..865
Misc Feature(1)212..433(+)
Misc Feature(2)464..745(+)
Misc Feature(3)479..643(+)
Misc Feature(4)542..640(+)
Exon (1)1..188
Gene:HLA-DQB1
Gene Synonym:
Exon (2)189..458
Gene:HLA-DQB1
Gene Synonym:
Exon (3)459..740
Gene:HLA-DQB1
Gene Synonym:
Exon (4)741..851
Gene:HLA-DQB1
Gene Synonym:
Exon (5)852..1638
Gene:HLA-DQB1
Gene Synonym:
Translation
Position Chain Variation Link
20 20 c, g dbSNP:3210146
31 31 c, g dbSNP:754079233
37 37 a, g dbSNP:766611168
38 38 a, g dbSNP:371168889
41 41 c, t dbSNP:67147537
42 42 a, g dbSNP:1049070
62 62 c, t dbSNP:775216584
68 68 c, t dbSNP:551381124
70 70 c, t dbSNP:34236112
73 73 c, g, t dbSNP:770457774
75 75 c, t dbSNP:746435665
76 76 -, agt dbSNP:758753379
77 77 a, g dbSNP:1049055
84 84 a, c dbSNP:772511655
91 91 a, g dbSNP:9274522
91 91 -, g dbSNP:748378081
95 95 g, t dbSNP:1049056
109 109 c, t dbSNP:1049072
114 114 a, g dbSNP:1049057
115 115 c, g, t dbSNP:756234491
121 121 g, t dbSNP:750530800
122 122 a, g dbSNP:767634513
123 123 a, c, t dbSNP:3189152
124 124 a, g dbSNP:369709024
125 125 c, g dbSNP:36222416
129 129 c, t dbSNP:759288400
133 133 a, c, g, t dbSNP:1049058
139 139 c, g dbSNP:772660704
140 140 a, g dbSNP:368832944
146 146 g, t dbSNP:3891176
147 147 a, c dbSNP:575475309
148 148 a, g dbSNP:372512148
150 150 c, t dbSNP:749609676
151 151 c, g dbSNP:1049059
156 156 g, t dbSNP:769981529
158 158 a, g, t dbSNP:1049060
159 159 -, tt dbSNP:778891121
160 160 c, t dbSNP:574506463
161 161 -, ct dbSNP:753527747
161 161 ct, tc dbSNP:67851506
161 161 c, t dbSNP:1049061
162 162 -, ta dbSNP:766371114
162 162 a, c, t dbSNP:1049062
162 162 -, t dbSNP:754778659
163 163 a, g dbSNP:1130373
164 164 -, cgg, gg dbSNP:749944694
164 164 c, g dbSNP:1130366
166 166 -, tg dbSNP:766997858
166 166 a, g dbSNP:200162904
168 168 c, t dbSNP:754779441
171 171 -, a dbSNP:761518101
172 172 g, t dbSNP:753690273
175 175 c, t dbSNP:780795041
180 180 a, c dbSNP:766158480
182 182 c, t dbSNP:12722106
185 185 c, t dbSNP:750064618
200 200 a, c, t dbSNP:12722107
201 201 a, t dbSNP:9274407
202 202 a, c dbSNP:111588946
208 208 a, t dbSNP:56173496
213 213 c, g, t dbSNP:1130375
215 215 a, c dbSNP:1130368
226 226 c, t dbSNP:748156342
230 230 a, g dbSNP:774283728
232 232 c, t dbSNP:3204373
233 233 a, g, t dbSNP:188170056
235 235 c, g dbSNP:72558170
238 238 a, c, g dbSNP:1049079
243 243 g, t dbSNP:41540813
245 245 a, g dbSNP:281862059
248 248 c, g, t dbSNP:546609663
249 249 -, ggg, gggg dbSNP:368078700
250 250 g, t dbSNP:1140310
251 251 -, ctt dbSNP:766817072
251 251 c, g, t dbSNP:12722115
252 252 a, g, t dbSNP:1049066
254 254 c, g dbSNP:41563539
256 256 a, g dbSNP:1049068
258 258 c, g dbSNP:9274405
259 259 c, t dbSNP:774531372
260 260 a, t dbSNP:41553112
262 262 -, ata dbSNP:761141840
263 263 a, c, g, t dbSNP:281862065
264 264 a, g dbSNP:767838657
266 266 a, g, t dbSNP:281862066
270 270 a, g dbSNP:281862067
271 271 c, t dbSNP:746746621
272 272 a, t dbSNP:777700493
273 273 a, g dbSNP:771914651
274 274 c, t dbSNP:45496594
275 275 a, c, t dbSNP:200200868
276 276 a, c, g dbSNP:75769070
280 280 a, g dbSNP:9274402
281 281 a, g, t dbSNP:754399219
283 283 c, g dbSNP:281862069
285 285 -, t dbSNP:750775556
285 285 a, t dbSNP:750855857
286 286 a, c dbSNP:767838386
287 287 a, g, t dbSNP:45519640
288 288 c, t dbSNP:1063318
289 289 a, g dbSNP:1049082
290 290 c, t dbSNP:762878587
291 291 a, g, t dbSNP:281862072
295 295 c, g dbSNP:281862073
296 296 g, t dbSNP:771052136
301 301 c, t dbSNP:760683225
302 302 g, t dbSNP:773178800
308 308 g, t dbSNP:281862074
309 309 a, g dbSNP:1049083
311 311 g, t dbSNP:281862076
312 312 a, t dbSNP:9274398
314 314 c, t dbSNP:773835804
315 315 a, g, t dbSNP:9274397
316 316 c, t dbSNP:1049073
317 317 c, t dbSNP:756656462
319 319 c, g dbSNP:3210148
321 321 c, t dbSNP:41558214
322 322 a, g dbSNP:1049074
324 324 c, t dbSNP:757521954
327 327 a, c, g dbSNP:200780973
328 328 c, g dbSNP:41561518
329 329 c, g dbSNP:199697520
330 330 a, c, t dbSNP:9274395
331 331 a, g dbSNP:752893795
332 332 a, c dbSNP:765374310
333 333 a, t dbSNP:1140313
338 338 c, t dbSNP:281862084
339 339 a, c, g, t dbSNP:1130380
340 340 c, g, t dbSNP:41557617
342 342 c, t dbSNP:1130381
343 343 -, a dbSNP:768143291
344 344 -, c dbSNP:762351772
344 344 a, g dbSNP:41552812
345 345 a, c, g, t dbSNP:1071637
346 346 -, cc, tg dbSNP:768610700
346 346 a, c, t dbSNP:1140314
349 349 a, c dbSNP:747394116
350 350 a, g dbSNP:778197829
353 353 a, t dbSNP:41562414
355 355 c, t dbSNP:41543717
357 357 c, g dbSNP:752942566
361 361 c, g, t dbSNP:1130382
364 364 c, g dbSNP:41556215
369 369 a, g dbSNP:755065210
373 373 a, c dbSNP:281874783
374 374 a, g dbSNP:9274390
375 375 a, t dbSNP:41563814
382 382 a, g dbSNP:281862092
383 383 -, a dbSNP:763272648
383 383 a, g dbSNP:1130386
384 384 -, gg dbSNP:775599585
384 384 a, g dbSNP:41563819
386 386 a, g dbSNP:1130390
387 387 a, c, t dbSNP:9274387
388 388 a, c dbSNP:9274386
389 389 -, c dbSNP:769966559
391 391 a, c, g, t dbSNP:3204379
392 392 -, agt dbSNP:745671219
392 392 g, t dbSNP:747522103
393 393 -, atc dbSNP:780910415
393 393 c, t dbSNP:281862099
394 394 -, tc dbSNP:770913644
394 394 a, g dbSNP:281862100
395 395 c, g, t dbSNP:1130385
396 396 -, agt dbSNP:777383993
396 396 -, a dbSNP:746916142
396 396 a, c, t dbSNP:1130387
396 396 ga, tc dbSNP:74195786
398 398 c, g, t dbSNP:9274384
400 400 g, t dbSNP:281862104
401 401 c, g, t dbSNP:281862105
403 403 c, t dbSNP:763827489
404 404 a, g dbSNP:281862106
405 405 c, g, t dbSNP:1130392
406 406 a, c, g dbSNP:1130389
407 407 g, t dbSNP:281862109
409 409 a, g, t dbSNP:1130391
410 410 c, t dbSNP:772565163
411 411 a, g dbSNP:748465792
412 412 c, t dbSNP:281862111
414 414 a, g dbSNP:281862112
415 415 a, g dbSNP:281862113
417 417 a, c, g dbSNP:281862114
420 420 a, g dbSNP:281862115
421 421 a, c dbSNP:769064881
422 422 c, t dbSNP:281862116
423 423 a, t dbSNP:749493826
425 425 c, g dbSNP:1140316
428 428 g, t dbSNP:1140317
431 431 a, g dbSNP:751456342
432 432 a, c, g dbSNP:9274380
433 433 -, gt dbSNP:757826441
434 434 c, t dbSNP:9274379
435 435 a, t dbSNP:17412833
438 438 -, aa dbSNP:752199956
438 438 c, g dbSNP:764988475
440 440 a, g dbSNP:1140318
441 441 -, gg dbSNP:778738052
441 441 c, g, t dbSNP:1140319
442 442 g, t dbSNP:760161370
444 444 a, c, t dbSNP:1140320
445 445 a, c dbSNP:762404924
446 446 c, t dbSNP:1130397
448 448 g, t dbSNP:769118061
449 449 c, g, t dbSNP:775715383
451 451 a, g dbSNP:769778552
452 452 a, c, t dbSNP:1140321
453 453 a, g dbSNP:758375041
454 454 g, t dbSNP:748058267
455 455 a, c, t dbSNP:1140322
456 456 g, t dbSNP:753433716
457 457 a, t dbSNP:765996014
458 458 a, c, g, t dbSNP:767102670
459 459 c, t dbSNP:9274030
460 460 a, g dbSNP:9274029
464 464 c, t dbSNP:761742182
467 467 a, t dbSNP:9274028
468 468 c, t dbSNP:281864111
470 470 a, g dbSNP:9274027
471 471 c, t dbSNP:9274026
472 472 c, g dbSNP:9274025
473 473 a, t dbSNP:765335255
475 475 c, t dbSNP:759515947
477 477 c, t dbSNP:9274024
480 480 c, g dbSNP:9274023
482 482 c, t dbSNP:9274022
483 483 c, g dbSNP:9274021
484 484 a, g dbSNP:9274020
486 486 -, tgct dbSNP:9282128
489 489 -, t dbSNP:9282127
493 493 a, g dbSNP:776619541
497 497 g, t dbSNP:9274019
498 498 c, t dbSNP:9274018
499 499 c, t dbSNP:9274017
504 504 a, t dbSNP:9274016
505 505 a, c dbSNP:746695492
508 508 c, g dbSNP:9274015
512 512 a, c dbSNP:9274014
514 514 a, c, g dbSNP:9274013
515 515 a, c dbSNP:9274012
517 517 c, g dbSNP:9274011
518 518 a, c dbSNP:9274010
519 519 a, t dbSNP:9274009
520 520 a, g dbSNP:9274008
521 521 a, g dbSNP:1049100
523 523 a, c dbSNP:747665984
524 524 c, t dbSNP:9274007
525 525 a, g dbSNP:778479681
526 526 c, g dbSNP:9274006
529 529 a, g dbSNP:1063321
530 530 a, g dbSNP:749771434
532 532 g, t dbSNP:9274005
533 533 a, t dbSNP:9274004
534 534 c, t dbSNP:780417441
535 535 a, g dbSNP:9274003
538 538 a, c, t dbSNP:9274002
540 540 -, tc dbSNP:373732791
540 540 g, t dbSNP:756429843
542 542 g, t dbSNP:9274001
543 543 a, g dbSNP:750661991
544 544 g, t dbSNP:767690361
545 545 c, g dbSNP:757497224
548 548 a, g dbSNP:1049107
549 549 -, a dbSNP:374741054
549 549 c, g dbSNP:1063322
550 550 c, g, t dbSNP:9273999
551 551 c, g dbSNP:9273998
553 553 c, g dbSNP:41542812
556 556 c, g, t dbSNP:281864116
559 559 a, c dbSNP:9273997
560 560 a, g, t dbSNP:9273996
561 561 g, t dbSNP:9273995
562 562 c, g dbSNP:9273994
563 563 c, t dbSNP:760326072
564 564 a, g dbSNP:41544112
565 565 g, t dbSNP:9273993
568 568 g, t dbSNP:9273992
569 569 g, t dbSNP:9273991
571 571 c, t dbSNP:9273990
572 572 c, t dbSNP:63626961
573 573 a, g dbSNP:9273989
574 574 c, g dbSNP:9273988
575 575 a, c dbSNP:9273987
576 576 a, c dbSNP:9273986
577 577 c, t dbSNP:9273985
578 578 c, g dbSNP:9273984
579 579 at, gc dbSNP:386699586
579 579 a, c, g dbSNP:2647032
580 580 c, t dbSNP:1049086
581 581 c, g, t dbSNP:9273981
583 583 g, t dbSNP:9273980
584 584 g, t dbSNP:9273979
585 585 a, g dbSNP:370212878
586 586 a, g dbSNP:41543118
587 587 -, gag dbSNP:762446214
587 587 a, g dbSNP:746286195
591 591 c, t dbSNP:781591845
593 593 act, gcc dbSNP:386699585
593 593 a, g dbSNP:1063323
594 594 c, g dbSNP:9273978
595 595 c, t dbSNP:1049087
596 596 a, g dbSNP:281864122
597 597 a, g dbSNP:9273976
598 598 c, t dbSNP:281864123
599 599 a, c, g dbSNP:281864124
605 605 a, t dbSNP:9273975
608 608 -, a dbSNP:369947362
608 608 a, g dbSNP:281864125
609 609 c, t dbSNP:9273974
610 610 c, t dbSNP:9273973
611 611 c, g dbSNP:766478201
612 612 c, g dbSNP:760652276
613 613 a, c dbSNP:9273972
614 614 -, c dbSNP:751976368
614 614 c, g, t dbSNP:9273971
615 615 a, t dbSNP:9273970
616 616 a, c, t dbSNP:1049088
617 617 a, g dbSNP:767317878
618 618 c, t dbSNP:9273968
620 620 a, g dbSNP:9273967
622 622 g, t dbSNP:9273966
623 623 a, g dbSNP:9273965
625 625 c, t dbSNP:1049130
627 627 c, g dbSNP:9273964
628 628 -, g dbSNP:9282125
630 630 a, c dbSNP:773951341
631 631 a, c dbSNP:9273963
632 632 a, t dbSNP:9273962
633 633 g, t dbSNP:9273961
637 637 c, t dbSNP:1049133
638 638 c, t dbSNP:398122358
639 639 c, t dbSNP:9273958
644 644 -, at dbSNP:9280010
647 647 c, g dbSNP:9273957
650 650 a, g dbSNP:375347079
651 651 a, t dbSNP:9273956
654 654 c, t dbSNP:9273955
655 655 -, t dbSNP:9282124
658 658 a, g dbSNP:9273954
659 659 c, g dbSNP:9273953
661 661 a, c dbSNP:9273952
662 662 a, c, g dbSNP:9273951
665 665 a, c dbSNP:9273950
667 667 a, t dbSNP:9273949
668 668 -, g dbSNP:9282123
669 669 c, t dbSNP:9273948
670 670 c, g dbSNP:9273947
671 671 -, c dbSNP:764281203
671 671 c, g dbSNP:9273946
674 674 -, a dbSNP:9282122
674 674 a, c dbSNP:746365289
675 675 -, gtggag dbSNP:762977143
675 675 a, c, g, t dbSNP:701564
677 677 -, gga dbSNP:281864128
677 677 c, g dbSNP:9273943
678 678 a, c, g dbSNP:9273942
679 679 -, a dbSNP:41548921
681 681 a, c dbSNP:41559620
682 682 c, g, t dbSNP:1049092
683 683 -, ccg dbSNP:775576363
683 683 a, g dbSNP:80255621
686 686 c, t dbSNP:9273939
688 688 c, g dbSNP:9273938
689 689 -, ac dbSNP:9282121
689 689 a, c dbSNP:758677458
690 690 c, t dbSNP:752887504
692 692 c, t dbSNP:9273937
693 693 a, g dbSNP:9273936
694 694 c, t dbSNP:9273935
696 696 -, t dbSNP:9282120
697 697 a, c, t dbSNP:281864130
698 698 a, g dbSNP:750324420
701 701 c, g dbSNP:767244736
704 704 c, t dbSNP:9273934
705 705 a, g dbSNP:9273933
706 706 a, c, g dbSNP:9273932
708 708 c, g dbSNP:9273931
709 709 c, t dbSNP:9273930
710 710 -, agg dbSNP:9282119
712 712 c, g dbSNP:9273929
713 713 a, c dbSNP:9273928
715 715 a, c dbSNP:9273927
716 716 c, t dbSNP:9273926
717 717 a, t dbSNP:9273925
720 720 -, t dbSNP:9282118
720 720 a, c, g, t dbSNP:1130398
721 721 a, c dbSNP:281864131
722 722 c, t dbSNP:9273923
724 724 c, t dbSNP:9273922
725 725 a, g dbSNP:9273921
726 726 c, t dbSNP:762561499
727 727 a, c, t dbSNP:9273920
729 729 c, t dbSNP:1130399
730 730 c, t dbSNP:398122512
731 731 a, g dbSNP:9273918
732 732 c, t dbSNP:281864132
733 733 g, t dbSNP:777132691
737 737 c, t dbSNP:9273917
738 738 c, g dbSNP:9273916
739 739 c, g dbSNP:9273915
740 740 c, t dbSNP:63267060
741 741 a, g dbSNP:9273667
743 743 c, g dbSNP:9273666
744 744 a, c dbSNP:9273665
745 745 a, t dbSNP:9273664
746 746 c, g dbSNP:9273663
747 747 a, g dbSNP:765779789
748 748 a, g, t dbSNP:9273660
749 749 g, t dbSNP:398122511
754 754 -, at dbSNP:374985918
756 756 c, g dbSNP:9273659
760 760 c, g dbSNP:9273658
763 763 g, t dbSNP:9273657
764 764 a, t dbSNP:9273656
765 765 a, g dbSNP:1130429
766 766 c, g dbSNP:398122483
768 768 a, g dbSNP:9273654
770 770 a, c dbSNP:9273653
772 772 g, t dbSNP:9273652
773 773 c, t dbSNP:767996356
776 776 a, g, t dbSNP:9273651
777 777 -, c dbSNP:9282094
780 780 a, g dbSNP:774564772
781 781 c, g, t dbSNP:9273650
782 782 a, c, g, t dbSNP:1049163
785 785 -, a dbSNP:9282093
786 786 g, t dbSNP:9273647
787 787 a, c dbSNP:9273646
788 788 g, t dbSNP:9273645
789 789 g, t dbSNP:9273644
790 790 c, t dbSNP:775662251
791 791 c, t dbSNP:9273643
795 795 g, t dbSNP:9273642
802 802 c, g dbSNP:9273641
805 805 c, g, t dbSNP:1130410
808 808 c, t dbSNP:9273639
809 809 a, t dbSNP:9273638
813 813 a, t dbSNP:9273637
814 814 c, t dbSNP:1130430
815 815 a, g dbSNP:777631827
816 816 c, g dbSNP:9273635
817 817 a, g dbSNP:9273634
820 820 a, g, t dbSNP:1130431
823 823 a, c dbSNP:9273632
824 824 c, g dbSNP:9273631
826 826 c, t dbSNP:9273630
829 829 c, g, t dbSNP:3210168
831 831 a, t dbSNP:9273628
832 832 a, c dbSNP:9273627
833 833 c, g, t dbSNP:9273626
834 834 a, g dbSNP:1140342
835 835 c, t dbSNP:779739215
838 838 a, c, g dbSNP:1140343
842 842 a, g, t dbSNP:201457654
843 843 a, g dbSNP:9273622
844 844 c, t dbSNP:9273621
846 846 a, c, g dbSNP:1130432
847 847 c, g dbSNP:398122510
850 850 a, g dbSNP:9273618
856 856 a, c, t dbSNP:1140347
860 860 c, t dbSNP:776366076
876 876 c, t dbSNP:139850766
877 877 a, g dbSNP:1049175
886 886 a, g, t dbSNP:1063343
887 887 a, g dbSNP:1049177
890 890 c, t dbSNP:1049178
892 892 g, t dbSNP:748609904
893 893 g, t dbSNP:779276671
895 895 c, t dbSNP:755264941
899 899 a, c dbSNP:201738242
902 902 a, c, g, t dbSNP:1063345
904 904 a, t dbSNP:766570827
906 906 g, t dbSNP:756357005
907 907 g, t dbSNP:750510294
909 909 a, g dbSNP:3204428
911 911 c, t dbSNP:1063346
912 912 g, t dbSNP:775501650
913 913 c, g dbSNP:765136994
915 915 a, t dbSNP:759460475
916 916 g, t dbSNP:776479724
920 920 atg, gtc dbSNP:386699569
920 920 a, g dbSNP:7656
922 922 c, g, t dbSNP:1063347
940 940 a, g dbSNP:36205178
944 944 c, t dbSNP:9273463
955 955 ctgtcccccgagatcag, ttgtccccctgagatcaa dbSNP:386699568
955 955 c, t dbSNP:1063348
956 956 g, t dbSNP:35888564
961 961 a, c dbSNP:779360470
964 964 -, t dbSNP:771958616
964 964 -, t dbSNP:3842708
967 967 a, g dbSNP:535153974
972 972 a, g dbSNP:1063349
993 993 a, g dbSNP:113664950
996 996 a, g dbSNP:1071639
1001 1001 c, t dbSNP:570286881
1026 1026 c, t dbSNP:1130420
1027 1027 c, g, t dbSNP:9273459
1028 1028 a, g dbSNP:3210176
1032 1032 -, g, t dbSNP:9282076
1035 1035 -, a dbSNP:281864466
1035 1035 a, c dbSNP:1130422
1046 1046 c, t dbSNP:1770
1049 1049 a, g dbSNP:9273455
1059 1059 c, g dbSNP:181293540
1061 1061 g, t dbSNP:1768
1061 1061 g, t dbSNP:115749644
1067 1067 c, g dbSNP:9273453
1072 1072 a, c, t dbSNP:1049122
1081 1081 a, g dbSNP:1071641
1084 1084 c, t dbSNP:1766
1085 1085 a, g dbSNP:1049123
1094 1094 c, t dbSNP:1764
1095 1095 a, g dbSNP:4993988
1095 1095 a, g dbSNP:78372297
1102 1102 c, g dbSNP:1762
1102 1102 c, g dbSNP:79471319
1106 1106 c, t dbSNP:1049213
1116 1116 a, t dbSNP:1049219
1121 1121 a, g dbSNP:183950119
1127 1127 a, g dbSNP:1049222
1132 1132 c, t dbSNP:1049225
1165 1165 a, c dbSNP:1063355
1166 1166 c, t dbSNP:1049124
1179 1179 c, t dbSNP:6689
1190 1190 -, t dbSNP:756361095
1211 1211 g, t dbSNP:3204433
1213 1213 a, g dbSNP:3210187
1216 1216 a, g dbSNP:3204434
1217 1217 a, g dbSNP:3204435
1225 1225 c, t dbSNP:117067420
1227 1227 c, g dbSNP:4993986
1227 1227 c, g dbSNP:78434421
1233 1233 c, t dbSNP:9273445
1236 1236 g, t dbSNP:1140365
1244 1244 a, c dbSNP:9273444
1252 1252 a, g dbSNP:34153824
1259 1259 a, g dbSNP:1130445
1262 1262 a, g dbSNP:1130446
1266 1266 a, g dbSNP:36205798
1276 1276 c, t dbSNP:117789582
1279 1279 a, c dbSNP:9273443
1296 1296 a, c dbSNP:545181996
1297 1297 a, c dbSNP:9273442
1306 1306 c, g dbSNP:9273441
1318 1318 a, g dbSNP:9273440
1344 1344 a, c dbSNP:28724234
1344 1344 -, c dbSNP:62998560
1345 1345 a, t dbSNP:9273439
1351 1351 g, t dbSNP:1130451
1355 1355 c, t dbSNP:9273438
1356 1356 -, ca dbSNP:765291761
1356 1356 a, c, g dbSNP:9273437
1361 1361 a, c dbSNP:9273436
1363 1363 g, t dbSNP:1056315
1384 1384 a, g dbSNP:1056316
1385 1385 -, c dbSNP:63031662
1386 1386 -, c dbSNP:9282075
1388 1388 a, c dbSNP:112615708
1390 1390 c, t dbSNP:9273433
1394 1394 a, g dbSNP:9273432
1399 1399 c, t dbSNP:1064173
1419 1419 a, c dbSNP:9273430
1423 1423 c, t dbSNP:9273429
1429 1429 c, t dbSNP:1056318
1433 1433 a, g dbSNP:28724233
1438 1438 g, t dbSNP:9273427
1445 1445 g, t dbSNP:9273426
1461 1461 c, g dbSNP:533116120
1474 1474 c, g dbSNP:1130455
1483 1483 a, g dbSNP:9273425
1485 1485 a, g dbSNP:9273424
1489 1489 a, g dbSNP:9273423
1490 1490 c, t dbSNP:751600196
1493 1493 a, g dbSNP:12918
1500 1500 a, g dbSNP:1130456
1512 1512 a, g dbSNP:1130457
1514 1514 a, g dbSNP:9273419
1517 1517 g, t dbSNP:9273418
1527 1527 c, t dbSNP:9273417
1542 1542 c, g dbSNP:537937592
1547 1547 -, a dbSNP:376622401
1549 1549 -, a dbSNP:34835883
1558 1558 a, c dbSNP:9273416
1569 1569 a, g dbSNP:9273415
1580 1580 a, t dbSNP:9273414
1587 1587 c, t dbSNP:9273413
1616 1616 a, g dbSNP:9273412
1619 1619 c, t dbSNP:9273411
1629 1629 g, t dbSNP:9273410
1637 1637 a, g dbSNP:111951747

Target ORF information:

RefSeq Version NM_001243962
Organism Homo sapiens (human)
Definition Homo sapiens major histocompatibility complex, class II, DQ beta 1 (HLA-DQB1), transcript variant 3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001243962

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGTCTTGGA AAAAGGCTTT GCGGATCCCC GGAGGCCTTC GGGCAGCAAC TGTGACCTTG 
ATGCTGTCGA TGCTGAGCAC CCCAGTGGCT GAGGGCAGAG ACTCTCCCGA GGATTTCGTG
TACCAGTTTA AGGGCATGTG CTACTTCACC AACGGGACAG AGCGCGTGCG TCTTGTGAGC
AGAAGCATCT ATAACCGAGA AGAGATCGTG CGCTTCGACA GCGACGTGGG GGAGTTCCGG
GCGGTGACGC TGCTGGGGCT GCCTGCCGCC GAGTACTGGA ACAGCCAGAA GGACATCCTG
GAGAGGAAAC GGGCGGCGGT GGACAGGGTG TGCAGACACA ACTACCAGTT GGAGCTCCGC
ACGACCTTGC AGCGGCGAGT GGAGCCCACA GTGACCATCT CCCCATCCAG GACAGAGGCC
CTCAACCACC ACAACCTGCT GGTCTGCTCG GTGACAGATT TCTATCCAGC CCAGATCAAA
GTCCGGTGGT TTCGGAATGA CCAGGAGGAG ACAGCTGGCG TTGTGTCCAC CCCCCTTATT
AGGAATGGTG ACTGGACCTT CCAGATCCTG GTGATGCTGG AAATGACTCC CCAGCGTGGA
GACGTCTACA CCTGCCACGT GGAGCACCCC AGCCTCCAGA GCCCCATCAC CGTGGAGTGG
CGGGCTCAAT CTGAATCTGC CCAGAGCAAG ATGCTGAGTG GCATTGGAGG CTTCGTGCTG
GGGCTGATCT TCCTCGGGCT GGGCCTTATC ATCCATCACA GGAGTCAGAA AGGGCTCCTG
CACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu26742
Accession Version NM_002123.4 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 786bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product HLA class II histocompatibility antigen, DQ beta 1 chain isoform 1 precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC409119.1, M25327.1, M20432.1, AK296613.1 and BF510934.1. On Sep 2, 2011 this sequence version replaced gi:150418001. Summary: HLA-DQB1 belongs to the HLA class II beta chain paralogs. This class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and it contains six exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to four different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011]. Transcript Variant: This variant (1) is the predominant transcript and encodes isoform 1. This transcript represents the DQB1*06:02:01:01 allele of the HLA-DQB1 gene, as represented in the assembled chromosome 6 in the primary assembly of the reference genome. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK296613.1, X03068.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2142586 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGTCTTGGA AGAAGGCTTT GCGGATCCCC GGAGACCTTC GGGTAGCAAC TGTCACCTTG 
ATGCTGGCGA TGCTGAGCTC CCTACTGGCT GAGGGCAGAG ACTCTCCCGA GGATTTCGTG
TTCCAGTTTA AGGGCATGTG CTACTTCACC AACGGGACGG AGCGCGTGCG TCTTGTGACC
AGATACATCT ATAACCGAGA GGAGTACGCG CGCTTCGACA GCGACGTGGG GGTGTACCGC
GCGGTGACGC CGCAGGGGCG GCCTGATGCC GAGTACTGGA ACAGCCAGAA GGAAGTCCTG
GAGGGGACCC GGGCGGAGTT GGACACGGTG TGCAGACACA ACTACGAGGT GGCGTTCCGC
GGGATCTTGC AGAGGAGAGT GGAGCCCACA GTGACCATCT CCCCATCCAG GACAGAGGCC
CTCAACCACC ACAACCTGCT GGTCTGCTCG GTGACAGATT TCTATCCAGG CCAGATCAAA
GTCCGGTGGT TTCGGAATGA TCAGGAGGAG ACAGCCGGCG TTGTGTCCAC CCCCCTTATT
AGGAATGGTG ACTGGACTTT CCAGATCCTG GTGATGCTGG AAATGACTCC CCAGCGTGGA
GATGTCTACA CCTGCCACGT GGAGCACCCC AGCCTCCAGA GCCCCATCAC CGTGGAGTGG
CGGGCTCAGT CTGAATCTGC CCAGAGCAAG ATGCTGAGTG GCGTTGGAGG CTTCGTGCTG
GGGCTGATCT TCCTTGGGCT GGGCCTTATC ATCCGTCAAA GGAGTCAGAA AGGGCTTCTG
CACTGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_002114.3
CDS83..868
Misc Feature(1)215..433(+)
Misc Feature(2)467..748(+)
Misc Feature(3)482..646(+)
Misc Feature(4)545..643(+)
Exon (1)1..191
Gene:HLA-DQB1
Gene Synonym:
Exon (2)192..461
Gene:HLA-DQB1
Gene Synonym:
Exon (3)462..743
Gene:HLA-DQB1
Gene Synonym:
Exon (4)744..854
Gene:HLA-DQB1
Gene Synonym:
Exon (5)855..1640
Gene:HLA-DQB1
Gene Synonym:
Translation
Position Chain Variation Link
20 20 c, g dbSNP:3210146
31 31 c, g dbSNP:754079233
37 37 a, g dbSNP:766611168
38 38 a, g dbSNP:371168889
41 41 c, t dbSNP:67147537
42 42 a, g dbSNP:1049070
62 62 -, gct dbSNP:71789649
62 62 a, g dbSNP:1049053
65 65 c, t dbSNP:775216584
71 71 c, t dbSNP:551381124
73 73 c, t dbSNP:34236112
76 76 c, g, t dbSNP:770457774
78 78 c, t dbSNP:746435665
79 79 -, agt dbSNP:758753379
80 80 a, g dbSNP:1049055
87 87 a, c dbSNP:772511655
94 94 a, g dbSNP:9274522
94 94 -, g dbSNP:748378081
98 98 g, t dbSNP:1049056
112 112 c, t dbSNP:1049072
117 117 a, g dbSNP:1049057
118 118 c, g, t dbSNP:756234491
124 124 g, t dbSNP:750530800
125 125 a, g dbSNP:767634513
126 126 a, c, t dbSNP:3189152
127 127 a, g dbSNP:369709024
128 128 c, g dbSNP:36222416
132 132 c, t dbSNP:759288400
136 136 a, c, g, t dbSNP:1049058
142 142 c, g dbSNP:772660704
143 143 a, g dbSNP:368832944
149 149 g, t dbSNP:3891176
150 150 a, c dbSNP:575475309
151 151 a, g dbSNP:372512148
153 153 c, t dbSNP:749609676
154 154 c, g dbSNP:1049059
159 159 g, t dbSNP:769981529
161 161 a, g, t dbSNP:1049060
162 162 -, tt dbSNP:778891121
163 163 c, t dbSNP:574506463
164 164 -, ct dbSNP:753527747
164 164 ct, tc dbSNP:67851506
164 164 c, t dbSNP:1049061
165 165 -, ta dbSNP:766371114
165 165 a, c, t dbSNP:1049062
165 165 -, t dbSNP:754778659
166 166 a, g dbSNP:1130373
167 167 -, cgg, gg dbSNP:749944694
167 167 c, g dbSNP:1130366
169 169 -, tg dbSNP:766997858
169 169 a, g dbSNP:200162904
171 171 c, t dbSNP:754779441
174 174 -, a dbSNP:761518101
175 175 g, t dbSNP:753690273
178 178 c, t dbSNP:780795041
183 183 a, c dbSNP:766158480
185 185 c, t dbSNP:12722106
188 188 c, t dbSNP:750064618
203 203 a, c, t dbSNP:12722107
204 204 a, t dbSNP:9274407
205 205 a, c dbSNP:111588946
211 211 a, t dbSNP:56173496
216 216 c, g, t dbSNP:1130375
218 218 a, c dbSNP:1130368
229 229 c, t dbSNP:748156342
233 233 a, g dbSNP:774283728
235 235 c, t dbSNP:3204373
236 236 a, g, t dbSNP:188170056
238 238 c, g dbSNP:72558170
241 241 a, c, g dbSNP:1049079
246 246 g, t dbSNP:41540813
248 248 a, g dbSNP:281862059
251 251 c, g, t dbSNP:546609663
252 252 -, ggg, gggg dbSNP:368078700
253 253 g, t dbSNP:1140310
254 254 -, ctt dbSNP:766817072
254 254 c, g, t dbSNP:12722115
255 255 a, g, t dbSNP:1049066
257 257 c, g dbSNP:41563539
259 259 a, g dbSNP:1049068
261 261 c, g dbSNP:9274405
262 262 c, t dbSNP:774531372
263 263 a, t dbSNP:41553112
265 265 -, ata dbSNP:761141840
266 266 a, c, g, t dbSNP:281862065
267 267 a, g dbSNP:767838657
269 269 a, g, t dbSNP:281862066
273 273 a, g dbSNP:281862067
274 274 c, t dbSNP:746746621
275 275 a, t dbSNP:777700493
276 276 a, g dbSNP:771914651
277 277 c, t dbSNP:45496594
278 278 a, c, t dbSNP:200200868
279 279 a, c, g dbSNP:75769070
283 283 a, g dbSNP:9274402
284 284 a, g, t dbSNP:754399219
286 286 c, g dbSNP:281862069
288 288 -, t dbSNP:750775556
288 288 a, t dbSNP:750855857
289 289 a, c dbSNP:767838386
290 290 a, g, t dbSNP:45519640
291 291 c, t dbSNP:1063318
292 292 a, g dbSNP:1049082
293 293 c, t dbSNP:762878587
294 294 a, g, t dbSNP:281862072
298 298 c, g dbSNP:281862073
299 299 g, t dbSNP:771052136
304 304 c, t dbSNP:760683225
305 305 g, t dbSNP:773178800
311 311 g, t dbSNP:281862074
312 312 a, g dbSNP:1049083
314 314 g, t dbSNP:281862076
315 315 a, t dbSNP:9274398
317 317 c, t dbSNP:773835804
318 318 a, g, t dbSNP:9274397
319 319 c, t dbSNP:1049073
320 320 c, t dbSNP:756656462
322 322 c, g dbSNP:3210148
324 324 c, t dbSNP:41558214
325 325 a, g dbSNP:1049074
327 327 c, t dbSNP:757521954
330 330 a, c, g dbSNP:200780973
331 331 c, g dbSNP:41561518
332 332 c, g dbSNP:199697520
333 333 a, c, t dbSNP:9274395
334 334 a, g dbSNP:752893795
335 335 a, c dbSNP:765374310
336 336 a, t dbSNP:1140313
341 341 c, t dbSNP:281862084
342 342 a, c, g, t dbSNP:1130380
343 343 c, g, t dbSNP:41557617
345 345 c, t dbSNP:1130381
346 346 -, a dbSNP:768143291
347 347 -, c dbSNP:762351772
347 347 a, g dbSNP:41552812
348 348 a, c, g, t dbSNP:1071637
349 349 -, cc, tg dbSNP:768610700
349 349 a, c, t dbSNP:1140314
352 352 a, c dbSNP:747394116
353 353 a, g dbSNP:778197829
356 356 a, t dbSNP:41562414
358 358 c, t dbSNP:41543717
360 360 c, g dbSNP:752942566
364 364 c, g, t dbSNP:1130382
367 367 c, g dbSNP:41556215
372 372 a, g dbSNP:755065210
376 376 a, c dbSNP:281874783
377 377 a, g dbSNP:9274390
378 378 a, t dbSNP:41563814
385 385 a, g dbSNP:281862092
386 386 -, a dbSNP:763272648
386 386 a, g dbSNP:1130386
387 387 -, gg dbSNP:775599585
387 387 a, g dbSNP:41563819
389 389 a, g dbSNP:1130390
390 390 a, c, t dbSNP:9274387
391 391 a, c dbSNP:9274386
392 392 -, c dbSNP:769966559
394 394 a, c, g, t dbSNP:3204379
395 395 -, agt dbSNP:745671219
395 395 g, t dbSNP:747522103
396 396 -, atc dbSNP:780910415
396 396 c, t dbSNP:281862099
397 397 -, tc dbSNP:770913644
397 397 a, g dbSNP:281862100
398 398 c, g, t dbSNP:1130385
399 399 -, agt dbSNP:777383993
399 399 -, a dbSNP:746916142
399 399 a, c, t dbSNP:1130387
399 399 ga, tc dbSNP:74195786
401 401 c, g, t dbSNP:9274384
403 403 g, t dbSNP:281862104
404 404 c, g, t dbSNP:281862105
406 406 c, t dbSNP:763827489
407 407 a, g dbSNP:281862106
408 408 c, g, t dbSNP:1130392
409 409 a, c, g dbSNP:1130389
410 410 g, t dbSNP:281862109
412 412 a, g, t dbSNP:1130391
413 413 c, t dbSNP:772565163
414 414 a, g dbSNP:748465792
415 415 c, t dbSNP:281862111
417 417 a, g dbSNP:281862112
418 418 a, g dbSNP:281862113
420 420 a, c, g dbSNP:281862114
423 423 a, g dbSNP:281862115
424 424 a, c dbSNP:769064881
425 425 c, t dbSNP:281862116
426 426 a, t dbSNP:749493826
428 428 c, g dbSNP:1140316
431 431 g, t dbSNP:1140317
434 434 a, g dbSNP:751456342
435 435 a, c, g dbSNP:9274380
436 436 -, gt dbSNP:757826441
437 437 c, t dbSNP:9274379
438 438 a, t dbSNP:17412833
441 441 -, aa dbSNP:752199956
441 441 c, g dbSNP:764988475
443 443 a, g dbSNP:1140318
444 444 -, gg dbSNP:778738052
444 444 c, g, t dbSNP:1140319
445 445 g, t dbSNP:760161370
447 447 a, c, t dbSNP:1140320
448 448 a, c dbSNP:762404924
449 449 c, t dbSNP:1130397
451 451 g, t dbSNP:769118061
452 452 c, g, t dbSNP:775715383
454 454 a, g dbSNP:769778552
455 455 a, c, t dbSNP:1140321
456 456 a, g dbSNP:758375041
457 457 g, t dbSNP:748058267
458 458 a, c, t dbSNP:1140322
459 459 g, t dbSNP:753433716
460 460 a, t dbSNP:765996014
461 461 a, c, g, t dbSNP:767102670
462 462 c, t dbSNP:9274030
463 463 a, g dbSNP:9274029
467 467 c, t dbSNP:761742182
470 470 a, t dbSNP:9274028
471 471 c, t dbSNP:281864111
473 473 a, g dbSNP:9274027
474 474 c, t dbSNP:9274026
475 475 c, g dbSNP:9274025
476 476 a, t dbSNP:765335255
478 478 c, t dbSNP:759515947
480 480 c, t dbSNP:9274024
483 483 c, g dbSNP:9274023
485 485 c, t dbSNP:9274022
486 486 c, g dbSNP:9274021
487 487 a, g dbSNP:9274020
489 489 -, tgct dbSNP:9282128
492 492 -, t dbSNP:9282127
496 496 a, g dbSNP:776619541
500 500 g, t dbSNP:9274019
501 501 c, t dbSNP:9274018
502 502 c, t dbSNP:9274017
507 507 a, t dbSNP:9274016
508 508 a, c dbSNP:746695492
511 511 c, g dbSNP:9274015
515 515 a, c dbSNP:9274014
517 517 a, c, g dbSNP:9274013
518 518 a, c dbSNP:9274012
520 520 c, g dbSNP:9274011
521 521 a, c dbSNP:9274010
522 522 a, t dbSNP:9274009
523 523 a, g dbSNP:9274008
524 524 a, g dbSNP:1049100
526 526 a, c dbSNP:747665984
527 527 c, t dbSNP:9274007
528 528 a, g dbSNP:778479681
529 529 c, g dbSNP:9274006
532 532 a, g dbSNP:1063321
533 533 a, g dbSNP:749771434
535 535 g, t dbSNP:9274005
536 536 a, t dbSNP:9274004
537 537 c, t dbSNP:780417441
538 538 a, g dbSNP:9274003
541 541 a, c, t dbSNP:9274002
543 543 -, tc dbSNP:373732791
543 543 g, t dbSNP:756429843
545 545 g, t dbSNP:9274001
546 546 a, g dbSNP:750661991
547 547 g, t dbSNP:767690361
548 548 c, g dbSNP:757497224
551 551 a, g dbSNP:1049107
552 552 -, a dbSNP:374741054
552 552 c, g dbSNP:1063322
553 553 c, g, t dbSNP:9273999
554 554 c, g dbSNP:9273998
556 556 c, g dbSNP:41542812
559 559 c, g, t dbSNP:281864116
562 562 a, c dbSNP:9273997
563 563 a, g, t dbSNP:9273996
564 564 g, t dbSNP:9273995
565 565 c, g dbSNP:9273994
566 566 c, t dbSNP:760326072
567 567 a, g dbSNP:41544112
568 568 g, t dbSNP:9273993
571 571 g, t dbSNP:9273992
572 572 g, t dbSNP:9273991
574 574 c, t dbSNP:9273990
575 575 c, t dbSNP:63626961
576 576 a, g dbSNP:9273989
577 577 c, g dbSNP:9273988
578 578 a, c dbSNP:9273987
579 579 a, c dbSNP:9273986
580 580 c, t dbSNP:9273985
581 581 c, g dbSNP:9273984
582 582 at, gc dbSNP:386699586
582 582 a, c, g dbSNP:2647032
583 583 c, t dbSNP:1049086
584 584 c, g, t dbSNP:9273981
586 586 g, t dbSNP:9273980
587 587 g, t dbSNP:9273979
588 588 a, g dbSNP:370212878
589 589 a, g dbSNP:41543118
590 590 -, gag dbSNP:762446214
590 590 a, g dbSNP:746286195
594 594 c, t dbSNP:781591845
596 596 act, gcc dbSNP:386699585
596 596 a, g dbSNP:1063323
597 597 c, g dbSNP:9273978
598 598 c, t dbSNP:1049087
599 599 a, g dbSNP:281864122
600 600 a, g dbSNP:9273976
601 601 c, t dbSNP:281864123
602 602 a, c, g dbSNP:281864124
608 608 a, t dbSNP:9273975
611 611 -, a dbSNP:369947362
611 611 a, g dbSNP:281864125
612 612 c, t dbSNP:9273974
613 613 c, t dbSNP:9273973
614 614 c, g dbSNP:766478201
615 615 c, g dbSNP:760652276
616 616 a, c dbSNP:9273972
617 617 -, c dbSNP:751976368
617 617 c, g, t dbSNP:9273971
618 618 a, t dbSNP:9273970
619 619 a, c, t dbSNP:1049088
620 620 a, g dbSNP:767317878
621 621 c, t dbSNP:9273968
623 623 a, g dbSNP:9273967
625 625 g, t dbSNP:9273966
626 626 a, g dbSNP:9273965
628 628 c, t dbSNP:1049130
630 630 c, g dbSNP:9273964
631 631 -, g dbSNP:9282125
633 633 a, c dbSNP:773951341
634 634 a, c dbSNP:9273963
635 635 a, t dbSNP:9273962
636 636 g, t dbSNP:9273961
640 640 c, t dbSNP:1049133
641 641 c, t dbSNP:398122358
642 642 c, t dbSNP:9273958
647 647 -, at dbSNP:9280010
650 650 c, g dbSNP:9273957
653 653 a, g dbSNP:375347079
654 654 a, t dbSNP:9273956
657 657 c, t dbSNP:9273955
658 658 -, t dbSNP:9282124
661 661 a, g dbSNP:9273954
662 662 c, g dbSNP:9273953
664 664 a, c dbSNP:9273952
665 665 a, c, g dbSNP:9273951
668 668 a, c dbSNP:9273950
670 670 a, t dbSNP:9273949
671 671 -, g dbSNP:9282123
672 672 c, t dbSNP:9273948
673 673 c, g dbSNP:9273947
674 674 -, c dbSNP:764281203
674 674 c, g dbSNP:9273946
677 677 -, a dbSNP:9282122
677 677 a, c dbSNP:746365289
678 678 -, gtggag dbSNP:762977143
678 678 a, c, g, t dbSNP:701564
680 680 -, gga dbSNP:281864128
680 680 c, g dbSNP:9273943
681 681 a, c, g dbSNP:9273942
682 682 -, a dbSNP:41548921
684 684 a, c dbSNP:41559620
685 685 c, g, t dbSNP:1049092
686 686 -, ccg dbSNP:775576363
686 686 a, g dbSNP:80255621
689 689 c, t dbSNP:9273939
691 691 c, g dbSNP:9273938
692 692 -, ac dbSNP:9282121
692 692 a, c dbSNP:758677458
693 693 c, t dbSNP:752887504
695 695 c, t dbSNP:9273937
696 696 a, g dbSNP:9273936
697 697 c, t dbSNP:9273935
699 699 -, t dbSNP:9282120
700 700 a, c, t dbSNP:281864130
701 701 a, g dbSNP:750324420
704 704 c, g dbSNP:767244736
707 707 c, t dbSNP:9273934
708 708 a, g dbSNP:9273933
709 709 a, c, g dbSNP:9273932
711 711 c, g dbSNP:9273931
712 712 c, t dbSNP:9273930
713 713 -, agg dbSNP:9282119
715 715 c, g dbSNP:9273929
716 716 a, c dbSNP:9273928
718 718 a, c dbSNP:9273927
719 719 c, t dbSNP:9273926
720 720 a, t dbSNP:9273925
723 723 -, t dbSNP:9282118
723 723 a, c, g, t dbSNP:1130398
724 724 a, c dbSNP:281864131
725 725 c, t dbSNP:9273923
727 727 c, t dbSNP:9273922
728 728 a, g dbSNP:9273921
729 729 c, t dbSNP:762561499
730 730 a, c, t dbSNP:9273920
732 732 c, t dbSNP:1130399
733 733 c, t dbSNP:398122512
734 734 a, g dbSNP:9273918
735 735 c, t dbSNP:281864132
736 736 g, t dbSNP:777132691
740 740 c, t dbSNP:9273917
741 741 c, g dbSNP:9273916
742 742 c, g dbSNP:9273915
743 743 c, t dbSNP:63267060
744 744 a, g dbSNP:9273667
746 746 c, g dbSNP:9273666
747 747 a, c dbSNP:9273665
748 748 a, t dbSNP:9273664
749 749 c, g dbSNP:9273663
750 750 a, g dbSNP:765779789
751 751 a, g, t dbSNP:9273660
752 752 g, t dbSNP:398122511
757 757 -, at dbSNP:374985918
759 759 c, g dbSNP:9273659
763 763 c, g dbSNP:9273658
766 766 g, t dbSNP:9273657
767 767 a, t dbSNP:9273656
768 768 a, g dbSNP:1130429
769 769 c, g dbSNP:398122483
771 771 a, g dbSNP:9273654
773 773 a, c dbSNP:9273653
775 775 g, t dbSNP:9273652
776 776 c, t dbSNP:767996356
779 779 a, g, t dbSNP:9273651
780 780 -, c dbSNP:9282094
783 783 a, g dbSNP:774564772
784 784 c, g, t dbSNP:9273650
785 785 a, c, g, t dbSNP:1049163
788 788 -, a dbSNP:9282093
789 789 g, t dbSNP:9273647
790 790 a, c dbSNP:9273646
791 791 g, t dbSNP:9273645
792 792 g, t dbSNP:9273644
793 793 c, t dbSNP:775662251
794 794 c, t dbSNP:9273643
798 798 g, t dbSNP:9273642
805 805 c, g dbSNP:9273641
808 808 c, g, t dbSNP:1130410
811 811 c, t dbSNP:9273639
812 812 a, t dbSNP:9273638
816 816 a, t dbSNP:9273637
817 817 c, t dbSNP:1130430
818 818 a, g dbSNP:777631827
819 819 c, g dbSNP:9273635
820 820 a, g dbSNP:9273634
823 823 a, g, t dbSNP:1130431
826 826 a, c dbSNP:9273632
827 827 c, g dbSNP:9273631
829 829 c, t dbSNP:9273630
832 832 c, g, t dbSNP:3210168
834 834 a, t dbSNP:9273628
835 835 a, c dbSNP:9273627
836 836 c, g, t dbSNP:9273626
837 837 a, g dbSNP:1140342
838 838 c, t dbSNP:779739215
841 841 a, c, g dbSNP:1140343
845 845 a, g, t dbSNP:201457654
846 846 a, g dbSNP:9273622
847 847 c, t dbSNP:9273621
849 849 a, c, g dbSNP:1130432
850 850 c, g dbSNP:398122510
853 853 a, g dbSNP:9273618
859 859 a, c, t dbSNP:1140347
863 863 c, t dbSNP:776366076
879 879 c, t dbSNP:139850766
880 880 a, g dbSNP:1049175
889 889 a, g, t dbSNP:1063343
890 890 a, g dbSNP:1049177
893 893 c, t dbSNP:1049178
895 895 g, t dbSNP:748609904
896 896 g, t dbSNP:779276671
898 898 c, t dbSNP:755264941
902 902 a, c dbSNP:201738242
905 905 a, c, g, t dbSNP:1063345
907 907 a, t dbSNP:766570827
909 909 g, t dbSNP:756357005
910 910 g, t dbSNP:750510294
912 912 a, g dbSNP:3204428
914 914 c, t dbSNP:1063346
915 915 g, t dbSNP:775501650
916 916 c, g dbSNP:765136994
918 918 a, t dbSNP:759460475
919 919 g, t dbSNP:776479724
923 923 atg, gtc dbSNP:386699569
923 923 a, g dbSNP:7656
925 925 c, g, t dbSNP:1063347
943 943 a, g dbSNP:36205178
947 947 c, t dbSNP:9273463
958 958 ctgtcccccgagatcag, ttgtccccctgagatcaa dbSNP:386699568
958 958 c, t dbSNP:1063348
959 959 g, t dbSNP:35888564
964 964 a, c dbSNP:779360470
967 967 -, t dbSNP:771958616
967 967 -, t dbSNP:3842708
970 970 a, g dbSNP:535153974
975 975 a, g dbSNP:1063349
996 996 a, g dbSNP:113664950
999 999 a, g dbSNP:1071639
1004 1004 c, t dbSNP:570286881
1029 1029 c, t dbSNP:1130420
1030 1030 c, g, t dbSNP:9273459
1031 1031 a, g dbSNP:3210176
1035 1035 -, g, t dbSNP:9282076
1048 1048 c, t dbSNP:1770
1051 1051 a, g dbSNP:9273455
1061 1061 c, g dbSNP:181293540
1063 1063 g, t dbSNP:1768
1063 1063 g, t dbSNP:115749644
1069 1069 c, g dbSNP:9273453
1074 1074 a, c, t dbSNP:1049122
1083 1083 a, g dbSNP:1071641
1086 1086 c, t dbSNP:1766
1087 1087 a, g dbSNP:1049123
1096 1096 c, t dbSNP:1764
1097 1097 a, g dbSNP:4993988
1097 1097 a, g dbSNP:78372297
1104 1104 c, g dbSNP:1762
1104 1104 c, g dbSNP:79471319
1108 1108 c, t dbSNP:1049213
1118 1118 a, t dbSNP:1049219
1123 1123 a, g dbSNP:183950119
1129 1129 a, g dbSNP:1049222
1134 1134 c, t dbSNP:1049225
1167 1167 a, c dbSNP:1063355
1168 1168 c, t dbSNP:1049124
1181 1181 c, t dbSNP:6689
1192 1192 -, t dbSNP:756361095
1213 1213 g, t dbSNP:3204433
1215 1215 a, g dbSNP:3210187
1218 1218 a, g dbSNP:3204434
1219 1219 a, g dbSNP:3204435
1227 1227 c, t dbSNP:117067420
1229 1229 c, g dbSNP:4993986
1229 1229 c, g dbSNP:78434421
1235 1235 c, t dbSNP:9273445
1238 1238 g, t dbSNP:1140365
1246 1246 a, c dbSNP:9273444
1254 1254 a, g dbSNP:34153824
1261 1261 a, g dbSNP:1130445
1264 1264 a, g dbSNP:1130446
1268 1268 a, g dbSNP:36205798
1278 1278 c, t dbSNP:117789582
1281 1281 a, c dbSNP:9273443
1298 1298 a, c dbSNP:545181996
1299 1299 a, c dbSNP:9273442
1308 1308 c, g dbSNP:9273441
1320 1320 a, g dbSNP:9273440
1346 1346 a, c dbSNP:28724234
1346 1346 -, c dbSNP:62998560
1347 1347 a, t dbSNP:9273439
1354 1354 g, t dbSNP:1130451
1358 1358 c, t dbSNP:9273438
1359 1359 -, ca dbSNP:765291761
1359 1359 a, c, g dbSNP:9273437
1364 1364 a, c dbSNP:9273436
1366 1366 g, t dbSNP:1056315
1387 1387 a, g dbSNP:1056316
1388 1388 -, c dbSNP:63031662
1389 1389 -, c dbSNP:9282075
1390 1390 a, c dbSNP:112615708
1392 1392 c, t dbSNP:9273433
1396 1396 a, g dbSNP:9273432
1401 1401 c, t dbSNP:1064173
1421 1421 a, c dbSNP:9273430
1425 1425 c, t dbSNP:9273429
1431 1431 c, t dbSNP:1056318
1435 1435 a, g dbSNP:28724233
1440 1440 g, t dbSNP:9273427
1447 1447 g, t dbSNP:9273426
1463 1463 c, g dbSNP:533116120
1476 1476 c, g dbSNP:1130455
1485 1485 a, g dbSNP:9273425
1487 1487 a, g dbSNP:9273424
1491 1491 a, g dbSNP:9273423
1492 1492 c, t dbSNP:751600196
1495 1495 a, g dbSNP:12918
1502 1502 a, g dbSNP:1130456
1514 1514 a, g dbSNP:1130457
1516 1516 a, g dbSNP:9273419
1519 1519 g, t dbSNP:9273418
1529 1529 c, t dbSNP:9273417
1544 1544 c, g dbSNP:537937592
1549 1549 -, a dbSNP:376622401
1551 1551 -, a dbSNP:34835883
1560 1560 a, c dbSNP:9273416
1571 1571 a, g dbSNP:9273415
1582 1582 a, t dbSNP:9273414
1589 1589 c, t dbSNP:9273413
1618 1618 a, g dbSNP:9273412
1621 1621 c, t dbSNP:9273411
1631 1631 g, t dbSNP:9273410
1639 1639 a, g dbSNP:111951747

Target ORF information:

RefSeq Version NM_002123
Organism Homo sapiens (human)
Definition Homo sapiens major histocompatibility complex, class II, DQ beta 1 (HLA-DQB1), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_002123

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGTCTTGGA AGAAGGCTTT GCGGATCCCC GGAGACCTTC GGGTAGCAAC TGTCACCTTG 
ATGCTGGCGA TGCTGAGCTC CCTACTGGCT GAGGGCAGAG ACTCTCCCGA GGATTTCGTG
TTCCAGTTTA AGGGCATGTG CTACTTCACC AACGGGACGG AGCGCGTGCG TCTTGTGACC
AGATACATCT ATAACCGAGA GGAGTACGCG CGCTTCGACA GCGACGTGGG GGTGTACCGC
GCGGTGACGC CGCAGGGGCG GCCTGATGCC GAGTACTGGA ACAGCCAGAA GGAAGTCCTG
GAGGGGACCC GGGCGGAGTT GGACACGGTG TGCAGACACA ACTACGAGGT GGCGTTCCGC
GGGATCTTGC AGAGGAGAGT GGAGCCCACA GTGACCATCT CCCCATCCAG GACAGAGGCC
CTCAACCACC ACAACCTGCT GGTCTGCTCG GTGACAGATT TCTATCCAGG CCAGATCAAA
GTCCGGTGGT TTCGGAATGA TCAGGAGGAG ACAGCCGGCG TTGTGTCCAC CCCCCTTATT
AGGAATGGTG ACTGGACTTT CCAGATCCTG GTGATGCTGG AAATGACTCC CCAGCGTGGA
GATGTCTACA CCTGCCACGT GGAGCACCCC AGCCTCCAGA GCCCCATCAC CGTGGAGTGG
CGGGCTCAGT CTGAATCTGC CCAGAGCAAG ATGCTGAGTG GCGTTGGAGG CTTCGTGCTG
GGGCTGATCT TCCTTGGGCT GGGCCTTATC ATCCGTCAAA GGAGTCAGAA AGGGCTTCTG
CACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu20771
Accession Version NM_001243961.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 810bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product HLA class II histocompatibility antigen, DQ beta 1 chain isoform 2 precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL662789.11. Summary: HLA-DQB1 belongs to the HLA class II beta chain paralogs. This class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and it contains six exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to four different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011]. Transcript Variant: This variant (2) includes an alternate in-frame exon in the coding region, compared to variant 1. It encodes isoform 2 which is longer than isoform 1. This transcript represents the DQB1*06:02:01:01 allele of the HLA-DQB1 gene, as represented in the assembled chromosome 6 in the primary assembly of the reference genome. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M16276.1, M57649.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGTCTTGGA AGAAGGCTTT GCGGATCCCC GGAGACCTTC GGGTAGCAAC TGTCACCTTG 
ATGCTGGCGA TGCTGAGCTC CCTACTGGCT GAGGGCAGAG ACTCTCCCGA GGATTTCGTG
TTCCAGTTTA AGGGCATGTG CTACTTCACC AACGGGACGG AGCGCGTGCG TCTTGTGACC
AGATACATCT ATAACCGAGA GGAGTACGCG CGCTTCGACA GCGACGTGGG GGTGTACCGC
GCGGTGACGC CGCAGGGGCG GCCTGATGCC GAGTACTGGA ACAGCCAGAA GGAAGTCCTG
GAGGGGACCC GGGCGGAGTT GGACACGGTG TGCAGACACA ACTACGAGGT GGCGTTCCGC
GGGATCTTGC AGAGGAGAGT GGAGCCCACA GTGACCATCT CCCCATCCAG GACAGAGGCC
CTCAACCACC ACAACCTGCT GGTCTGCTCG GTGACAGATT TCTATCCAGG CCAGATCAAA
GTCCGGTGGT TTCGGAATGA TCAGGAGGAG ACAGCCGGCG TTGTGTCCAC CCCCCTTATT
AGGAATGGTG ACTGGACTTT CCAGATCCTG GTGATGCTGG AAATGACTCC CCAGCGTGGA
GATGTCTACA CCTGCCACGT GGAGCACCCC AGCCTCCAGA GCCCCATCAC CGTGGAGTGG
CGGGCTCAGT CTGAATCTGC CCAGAGCAAG ATGCTGAGTG GCGTTGGAGG CTTCGTGCTG
GGGCTGATCT TCCTTGGGCT GGGCCTTATC ATCCGTCAAA GGAGTCAGAA AGGACCTCAA
GGGCCTCCAC CAGCAGGGCT TCTGCACTGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_001230890.1
CDS83..892
Misc Feature(1)215..433(+)
Misc Feature(2)467..748(+)
Misc Feature(3)482..646(+)
Misc Feature(4)545..643(+)
Exon (1)1..191
Gene:HLA-DQB1
Gene Synonym:
Exon (2)192..461
Gene:HLA-DQB1
Gene Synonym:
Exon (3)462..743
Gene:HLA-DQB1
Gene Synonym:
Exon (4)744..854
Gene:HLA-DQB1
Gene Synonym:
Exon (5)855..878
Gene:HLA-DQB1
Gene Synonym:
Exon (6)879..1664
Gene:HLA-DQB1
Gene Synonym:
Translation
Position Chain Variation Link
20 20 c, g dbSNP:3210146
31 31 c, g dbSNP:754079233
37 37 a, g dbSNP:766611168
38 38 a, g dbSNP:371168889
41 41 c, t dbSNP:67147537
42 42 a, g dbSNP:1049070
62 62 -, gct dbSNP:71789649
62 62 a, g dbSNP:1049053
65 65 c, t dbSNP:775216584
71 71 c, t dbSNP:551381124
73 73 c, t dbSNP:34236112
76 76 c, g, t dbSNP:770457774
78 78 c, t dbSNP:746435665
79 79 -, agt dbSNP:758753379
80 80 a, g dbSNP:1049055
87 87 a, c dbSNP:772511655
94 94 a, g dbSNP:9274522
94 94 -, g dbSNP:748378081
98 98 g, t dbSNP:1049056
112 112 c, t dbSNP:1049072
117 117 a, g dbSNP:1049057
118 118 c, g, t dbSNP:756234491
124 124 g, t dbSNP:750530800
125 125 a, g dbSNP:767634513
126 126 a, c, t dbSNP:3189152
127 127 a, g dbSNP:369709024
128 128 c, g dbSNP:36222416
132 132 c, t dbSNP:759288400
136 136 a, c, g, t dbSNP:1049058
142 142 c, g dbSNP:772660704
143 143 a, g dbSNP:368832944
149 149 g, t dbSNP:3891176
150 150 a, c dbSNP:575475309
151 151 a, g dbSNP:372512148
153 153 c, t dbSNP:749609676
154 154 c, g dbSNP:1049059
159 159 g, t dbSNP:769981529
161 161 a, g, t dbSNP:1049060
162 162 -, tt dbSNP:778891121
163 163 c, t dbSNP:574506463
164 164 -, ct dbSNP:753527747
164 164 ct, tc dbSNP:67851506
164 164 c, t dbSNP:1049061
165 165 -, ta dbSNP:766371114
165 165 a, c, t dbSNP:1049062
165 165 -, t dbSNP:754778659
166 166 a, g dbSNP:1130373
167 167 -, cgg, gg dbSNP:749944694
167 167 c, g dbSNP:1130366
169 169 -, tg dbSNP:766997858
169 169 a, g dbSNP:200162904
171 171 c, t dbSNP:754779441
174 174 -, a dbSNP:761518101
175 175 g, t dbSNP:753690273
178 178 c, t dbSNP:780795041
183 183 a, c dbSNP:766158480
185 185 c, t dbSNP:12722106
188 188 c, t dbSNP:750064618
203 203 a, c, t dbSNP:12722107
204 204 a, t dbSNP:9274407
205 205 a, c dbSNP:111588946
211 211 a, t dbSNP:56173496
216 216 c, g, t dbSNP:1130375
218 218 a, c dbSNP:1130368
229 229 c, t dbSNP:748156342
233 233 a, g dbSNP:774283728
235 235 c, t dbSNP:3204373
236 236 a, g, t dbSNP:188170056
238 238 c, g dbSNP:72558170
241 241 a, c, g dbSNP:1049079
246 246 g, t dbSNP:41540813
248 248 a, g dbSNP:281862059
251 251 c, g, t dbSNP:546609663
252 252 -, ggg, gggg dbSNP:368078700
253 253 g, t dbSNP:1140310
254 254 -, ctt dbSNP:766817072
254 254 c, g, t dbSNP:12722115
255 255 a, g, t dbSNP:1049066
257 257 c, g dbSNP:41563539
259 259 a, g dbSNP:1049068
261 261 c, g dbSNP:9274405
262 262 c, t dbSNP:774531372
263 263 a, t dbSNP:41553112
265 265 -, ata dbSNP:761141840
266 266 a, c, g, t dbSNP:281862065
267 267 a, g dbSNP:767838657
269 269 a, g, t dbSNP:281862066
273 273 a, g dbSNP:281862067
274 274 c, t dbSNP:746746621
275 275 a, t dbSNP:777700493
276 276 a, g dbSNP:771914651
277 277 c, t dbSNP:45496594
278 278 a, c, t dbSNP:200200868
279 279 a, c, g dbSNP:75769070
283 283 a, g dbSNP:9274402
284 284 a, g, t dbSNP:754399219
286 286 c, g dbSNP:281862069
288 288 -, t dbSNP:750775556
288 288 a, t dbSNP:750855857
289 289 a, c dbSNP:767838386
290 290 a, g, t dbSNP:45519640
291 291 c, t dbSNP:1063318
292 292 a, g dbSNP:1049082
293 293 c, t dbSNP:762878587
294 294 a, g, t dbSNP:281862072
298 298 c, g dbSNP:281862073
299 299 g, t dbSNP:771052136
304 304 c, t dbSNP:760683225
305 305 g, t dbSNP:773178800
311 311 g, t dbSNP:281862074
312 312 a, g dbSNP:1049083
314 314 g, t dbSNP:281862076
315 315 a, t dbSNP:9274398
317 317 c, t dbSNP:773835804
318 318 a, g, t dbSNP:9274397
319 319 c, t dbSNP:1049073
320 320 c, t dbSNP:756656462
322 322 c, g dbSNP:3210148
324 324 c, t dbSNP:41558214
325 325 a, g dbSNP:1049074
327 327 c, t dbSNP:757521954
330 330 a, c, g dbSNP:200780973
331 331 c, g dbSNP:41561518
332 332 c, g dbSNP:199697520
333 333 a, c, t dbSNP:9274395
334 334 a, g dbSNP:752893795
335 335 a, c dbSNP:765374310
336 336 a, t dbSNP:1140313
341 341 c, t dbSNP:281862084
342 342 a, c, g, t dbSNP:1130380
343 343 c, g, t dbSNP:41557617
345 345 c, t dbSNP:1130381
346 346 -, a dbSNP:768143291
347 347 -, c dbSNP:762351772
347 347 a, g dbSNP:41552812
348 348 a, c, g, t dbSNP:1071637
349 349 -, cc, tg dbSNP:768610700
349 349 a, c, t dbSNP:1140314
352 352 a, c dbSNP:747394116
353 353 a, g dbSNP:778197829
356 356 a, t dbSNP:41562414
358 358 c, t dbSNP:41543717
360 360 c, g dbSNP:752942566
364 364 c, g, t dbSNP:1130382
367 367 c, g dbSNP:41556215
372 372 a, g dbSNP:755065210
376 376 a, c dbSNP:281874783
377 377 a, g dbSNP:9274390
378 378 a, t dbSNP:41563814
385 385 a, g dbSNP:281862092
386 386 -, a dbSNP:763272648
386 386 a, g dbSNP:1130386
387 387 -, gg dbSNP:775599585
387 387 a, g dbSNP:41563819
389 389 a, g dbSNP:1130390
390 390 a, c, t dbSNP:9274387
391 391 a, c dbSNP:9274386
392 392 -, c dbSNP:769966559
394 394 a, c, g, t dbSNP:3204379
395 395 -, agt dbSNP:745671219
395 395 g, t dbSNP:747522103
396 396 -, atc dbSNP:780910415
396 396 c, t dbSNP:281862099
397 397 -, tc dbSNP:770913644
397 397 a, g dbSNP:281862100
398 398 c, g, t dbSNP:1130385
399 399 -, agt dbSNP:777383993
399 399 -, a dbSNP:746916142
399 399 a, c, t dbSNP:1130387
399 399 ga, tc dbSNP:74195786
401 401 c, g, t dbSNP:9274384
403 403 g, t dbSNP:281862104
404 404 c, g, t dbSNP:281862105
406 406 c, t dbSNP:763827489
407 407 a, g dbSNP:281862106
408 408 c, g, t dbSNP:1130392
409 409 a, c, g dbSNP:1130389
410 410 g, t dbSNP:281862109
412 412 a, g, t dbSNP:1130391
413 413 c, t dbSNP:772565163
414 414 a, g dbSNP:748465792
415 415 c, t dbSNP:281862111
417 417 a, g dbSNP:281862112
418 418 a, g dbSNP:281862113
420 420 a, c, g dbSNP:281862114
423 423 a, g dbSNP:281862115
424 424 a, c dbSNP:769064881
425 425 c, t dbSNP:281862116
426 426 a, t dbSNP:749493826
428 428 c, g dbSNP:1140316
431 431 g, t dbSNP:1140317
434 434 a, g dbSNP:751456342
435 435 a, c, g dbSNP:9274380
436 436 -, gt dbSNP:757826441
437 437 c, t dbSNP:9274379
438 438 a, t dbSNP:17412833
441 441 -, aa dbSNP:752199956
441 441 c, g dbSNP:764988475
443 443 a, g dbSNP:1140318
444 444 -, gg dbSNP:778738052
444 444 c, g, t dbSNP:1140319
445 445 g, t dbSNP:760161370
447 447 a, c, t dbSNP:1140320
448 448 a, c dbSNP:762404924
449 449 c, t dbSNP:1130397
451 451 g, t dbSNP:769118061
452 452 c, g, t dbSNP:775715383
454 454 a, g dbSNP:769778552
455 455 a, c, t dbSNP:1140321
456 456 a, g dbSNP:758375041
457 457 g, t dbSNP:748058267
458 458 a, c, t dbSNP:1140322
459 459 g, t dbSNP:753433716
460 460 a, t dbSNP:765996014
461 461 a, c, g, t dbSNP:767102670
462 462 c, t dbSNP:9274030
463 463 a, g dbSNP:9274029
467 467 c, t dbSNP:761742182
470 470 a, t dbSNP:9274028
471 471 c, t dbSNP:281864111
473 473 a, g dbSNP:9274027
474 474 c, t dbSNP:9274026
475 475 c, g dbSNP:9274025
476 476 a, t dbSNP:765335255
478 478 c, t dbSNP:759515947
480 480 c, t dbSNP:9274024
483 483 c, g dbSNP:9274023
485 485 c, t dbSNP:9274022
486 486 c, g dbSNP:9274021
487 487 a, g dbSNP:9274020
489 489 -, tgct dbSNP:9282128
492 492 -, t dbSNP:9282127
496 496 a, g dbSNP:776619541
500 500 g, t dbSNP:9274019
501 501 c, t dbSNP:9274018
502 502 c, t dbSNP:9274017
507 507 a, t dbSNP:9274016
508 508 a, c dbSNP:746695492
511 511 c, g dbSNP:9274015
515 515 a, c dbSNP:9274014
517 517 a, c, g dbSNP:9274013
518 518 a, c dbSNP:9274012
520 520 c, g dbSNP:9274011
521 521 a, c dbSNP:9274010
522 522 a, t dbSNP:9274009
523 523 a, g dbSNP:9274008
524 524 a, g dbSNP:1049100
526 526 a, c dbSNP:747665984
527 527 c, t dbSNP:9274007
528 528 a, g dbSNP:778479681
529 529 c, g dbSNP:9274006
532 532 a, g dbSNP:1063321
533 533 a, g dbSNP:749771434
535 535 g, t dbSNP:9274005
536 536 a, t dbSNP:9274004
537 537 c, t dbSNP:780417441
538 538 a, g dbSNP:9274003
541 541 a, c, t dbSNP:9274002
543 543 -, tc dbSNP:373732791
543 543 g, t dbSNP:756429843
545 545 g, t dbSNP:9274001
546 546 a, g dbSNP:750661991
547 547 g, t dbSNP:767690361
548 548 c, g dbSNP:757497224
551 551 a, g dbSNP:1049107
552 552 -, a dbSNP:374741054
552 552 c, g dbSNP:1063322
553 553 c, g, t dbSNP:9273999
554 554 c, g dbSNP:9273998
556 556 c, g dbSNP:41542812
559 559 c, g, t dbSNP:281864116
562 562 a, c dbSNP:9273997
563 563 a, g, t dbSNP:9273996
564 564 g, t dbSNP:9273995
565 565 c, g dbSNP:9273994
566 566 c, t dbSNP:760326072
567 567 a, g dbSNP:41544112
568 568 g, t dbSNP:9273993
571 571 g, t dbSNP:9273992
572 572 g, t dbSNP:9273991
574 574 c, t dbSNP:9273990
575 575 c, t dbSNP:63626961
576 576 a, g dbSNP:9273989
577 577 c, g dbSNP:9273988
578 578 a, c dbSNP:9273987
579 579 a, c dbSNP:9273986
580 580 c, t dbSNP:9273985
581 581 c, g dbSNP:9273984
582 582 at, gc dbSNP:386699586
582 582 a, c, g dbSNP:2647032
583 583 c, t dbSNP:1049086
584 584 c, g, t dbSNP:9273981
586 586 g, t dbSNP:9273980
587 587 g, t dbSNP:9273979
588 588 a, g dbSNP:370212878
589 589 a, g dbSNP:41543118
590 590 -, gag dbSNP:762446214
590 590 a, g dbSNP:746286195
594 594 c, t dbSNP:781591845
596 596 act, gcc dbSNP:386699585
596 596 a, g dbSNP:1063323
597 597 c, g dbSNP:9273978
598 598 c, t dbSNP:1049087
599 599 a, g dbSNP:281864122
600 600 a, g dbSNP:9273976
601 601 c, t dbSNP:281864123
602 602 a, c, g dbSNP:281864124
608 608 a, t dbSNP:9273975
611 611 -, a dbSNP:369947362
611 611 a, g dbSNP:281864125
612 612 c, t dbSNP:9273974
613 613 c, t dbSNP:9273973
614 614 c, g dbSNP:766478201
615 615 c, g dbSNP:760652276
616 616 a, c dbSNP:9273972
617 617 -, c dbSNP:751976368
617 617 c, g, t dbSNP:9273971
618 618 a, t dbSNP:9273970
619 619 a, c, t dbSNP:1049088
620 620 a, g dbSNP:767317878
621 621 c, t dbSNP:9273968
623 623 a, g dbSNP:9273967
625 625 g, t dbSNP:9273966
626 626 a, g dbSNP:9273965
628 628 c, t dbSNP:1049130
630 630 c, g dbSNP:9273964
631 631 -, g dbSNP:9282125
633 633 a, c dbSNP:773951341
634 634 a, c dbSNP:9273963
635 635 a, t dbSNP:9273962
636 636 g, t dbSNP:9273961
640 640 c, t dbSNP:1049133
641 641 c, t dbSNP:398122358
642 642 c, t dbSNP:9273958
647 647 -, at dbSNP:9280010
650 650 c, g dbSNP:9273957
653 653 a, g dbSNP:375347079
654 654 a, t dbSNP:9273956
657 657 c, t dbSNP:9273955
658 658 -, t dbSNP:9282124
661 661 a, g dbSNP:9273954
662 662 c, g dbSNP:9273953
664 664 a, c dbSNP:9273952
665 665 a, c, g dbSNP:9273951
668 668 a, c dbSNP:9273950
670 670 a, t dbSNP:9273949
671 671 -, g dbSNP:9282123
672 672 c, t dbSNP:9273948
673 673 c, g dbSNP:9273947
674 674 -, c dbSNP:764281203
674 674 c, g dbSNP:9273946
677 677 -, a dbSNP:9282122
677 677 a, c dbSNP:746365289
678 678 -, gtggag dbSNP:762977143
678 678 a, c, g, t dbSNP:701564
680 680 -, gga dbSNP:281864128
680 680 c, g dbSNP:9273943
681 681 a, c, g dbSNP:9273942
682 682 -, a dbSNP:41548921
684 684 a, c dbSNP:41559620
685 685 c, g, t dbSNP:1049092
686 686 -, ccg dbSNP:775576363
686 686 a, g dbSNP:80255621
689 689 c, t dbSNP:9273939
691 691 c, g dbSNP:9273938
692 692 -, ac dbSNP:9282121
692 692 a, c dbSNP:758677458
693 693 c, t dbSNP:752887504
695 695 c, t dbSNP:9273937
696 696 a, g dbSNP:9273936
697 697 c, t dbSNP:9273935
699 699 -, t dbSNP:9282120
700 700 a, c, t dbSNP:281864130
701 701 a, g dbSNP:750324420
704 704 c, g dbSNP:767244736
707 707 c, t dbSNP:9273934
708 708 a, g dbSNP:9273933
709 709 a, c, g dbSNP:9273932
711 711 c, g dbSNP:9273931
712 712 c, t dbSNP:9273930
713 713 -, agg dbSNP:9282119
715 715 c, g dbSNP:9273929
716 716 a, c dbSNP:9273928
718 718 a, c dbSNP:9273927
719 719 c, t dbSNP:9273926
720 720 a, t dbSNP:9273925
723 723 -, t dbSNP:9282118
723 723 a, c, g, t dbSNP:1130398
724 724 a, c dbSNP:281864131
725 725 c, t dbSNP:9273923
727 727 c, t dbSNP:9273922
728 728 a, g dbSNP:9273921
729 729 c, t dbSNP:762561499
730 730 a, c, t dbSNP:9273920
732 732 c, t dbSNP:1130399
733 733 c, t dbSNP:398122512
734 734 a, g dbSNP:9273918
735 735 c, t dbSNP:281864132
736 736 g, t dbSNP:777132691
740 740 c, t dbSNP:9273917
741 741 c, g dbSNP:9273916
742 742 c, g dbSNP:9273915
743 743 c, t dbSNP:63267060
744 744 a, g dbSNP:9273667
746 746 c, g dbSNP:9273666
747 747 a, c dbSNP:9273665
748 748 a, t dbSNP:9273664
749 749 c, g dbSNP:9273663
750 750 a, g dbSNP:765779789
751 751 a, g, t dbSNP:9273660
752 752 g, t dbSNP:398122511
757 757 -, at dbSNP:374985918
759 759 c, g dbSNP:9273659
763 763 c, g dbSNP:9273658
766 766 g, t dbSNP:9273657
767 767 a, t dbSNP:9273656
768 768 a, g dbSNP:1130429
769 769 c, g dbSNP:398122483
771 771 a, g dbSNP:9273654
773 773 a, c dbSNP:9273653
775 775 g, t dbSNP:9273652
776 776 c, t dbSNP:767996356
779 779 a, g, t dbSNP:9273651
780 780 -, c dbSNP:9282094
783 783 a, g dbSNP:774564772
784 784 c, g, t dbSNP:9273650
785 785 a, c, g, t dbSNP:1049163
788 788 -, a dbSNP:9282093
789 789 g, t dbSNP:9273647
790 790 a, c dbSNP:9273646
791 791 g, t dbSNP:9273645
792 792 g, t dbSNP:9273644
793 793 c, t dbSNP:775662251
794 794 c, t dbSNP:9273643
798 798 g, t dbSNP:9273642
805 805 c, g dbSNP:9273641
808 808 c, g, t dbSNP:1130410
811 811 c, t dbSNP:9273639
812 812 a, t dbSNP:9273638
816 816 a, t dbSNP:9273637
817 817 c, t dbSNP:1130430
818 818 a, g dbSNP:777631827
819 819 c, g dbSNP:9273635
820 820 a, g dbSNP:9273634
823 823 a, g, t dbSNP:1130431
826 826 a, c dbSNP:9273632
827 827 c, g dbSNP:9273631
829 829 c, t dbSNP:9273630
832 832 c, g, t dbSNP:3210168
834 834 a, t dbSNP:9273628
835 835 a, c dbSNP:9273627
836 836 c, g, t dbSNP:9273626
837 837 a, g dbSNP:1140342
838 838 c, t dbSNP:779739215
841 841 a, c, g dbSNP:1140343
845 845 a, g, t dbSNP:201457654
846 846 a, g dbSNP:9273622
847 847 c, t dbSNP:9273621
849 849 a, c, g dbSNP:1130432
850 850 c, g dbSNP:398122510
853 853 a, g dbSNP:9273618
883 883 a, c, t dbSNP:1140347
887 887 c, t dbSNP:776366076
903 903 c, t dbSNP:139850766
904 904 a, g dbSNP:1049175
913 913 a, g, t dbSNP:1063343
914 914 a, g dbSNP:1049177
917 917 c, t dbSNP:1049178
919 919 g, t dbSNP:748609904
920 920 g, t dbSNP:779276671
922 922 c, t dbSNP:755264941
926 926 a, c dbSNP:201738242
929 929 a, c, g, t dbSNP:1063345
931 931 a, t dbSNP:766570827
933 933 g, t dbSNP:756357005
934 934 g, t dbSNP:750510294
936 936 a, g dbSNP:3204428
938 938 c, t dbSNP:1063346
939 939 g, t dbSNP:775501650
940 940 c, g dbSNP:765136994
942 942 a, t dbSNP:759460475
943 943 g, t dbSNP:776479724
947 947 atg, gtc dbSNP:386699569
947 947 a, g dbSNP:7656
949 949 c, g, t dbSNP:1063347
967 967 a, g dbSNP:36205178
971 971 c, t dbSNP:9273463
982 982 ctgtcccccgagatcag, ttgtccccctgagatcaa dbSNP:386699568
982 982 c, t dbSNP:1063348
983 983 g, t dbSNP:35888564
988 988 a, c dbSNP:779360470
991 991 -, t dbSNP:771958616
991 991 -, t dbSNP:3842708
994 994 a, g dbSNP:535153974
999 999 a, g dbSNP:1063349
1020 1020 a, g dbSNP:113664950
1023 1023 a, g dbSNP:1071639
1028 1028 c, t dbSNP:570286881
1053 1053 c, t dbSNP:1130420
1054 1054 c, g, t dbSNP:9273459
1055 1055 a, g dbSNP:3210176
1059 1059 -, g, t dbSNP:9282076
1072 1072 c, t dbSNP:1770
1075 1075 a, g dbSNP:9273455
1085 1085 c, g dbSNP:181293540
1087 1087 g, t dbSNP:1768
1087 1087 g, t dbSNP:115749644
1093 1093 c, g dbSNP:9273453
1098 1098 a, c, t dbSNP:1049122
1107 1107 a, g dbSNP:1071641
1110 1110 c, t dbSNP:1766
1111 1111 a, g dbSNP:1049123
1120 1120 c, t dbSNP:1764
1121 1121 a, g dbSNP:4993988
1121 1121 a, g dbSNP:78372297
1128 1128 c, g dbSNP:1762
1128 1128 c, g dbSNP:79471319
1132 1132 c, t dbSNP:1049213
1142 1142 a, t dbSNP:1049219
1147 1147 a, g dbSNP:183950119
1153 1153 a, g dbSNP:1049222
1158 1158 c, t dbSNP:1049225
1191 1191 a, c dbSNP:1063355
1192 1192 c, t dbSNP:1049124
1205 1205 c, t dbSNP:6689
1216 1216 -, t dbSNP:756361095
1237 1237 g, t dbSNP:3204433
1239 1239 a, g dbSNP:3210187
1242 1242 a, g dbSNP:3204434
1243 1243 a, g dbSNP:3204435
1251 1251 c, t dbSNP:117067420
1253 1253 c, g dbSNP:4993986
1253 1253 c, g dbSNP:78434421
1259 1259 c, t dbSNP:9273445
1262 1262 g, t dbSNP:1140365
1270 1270 a, c dbSNP:9273444
1278 1278 a, g dbSNP:34153824
1285 1285 a, g dbSNP:1130445
1288 1288 a, g dbSNP:1130446
1292 1292 a, g dbSNP:36205798
1302 1302 c, t dbSNP:117789582
1305 1305 a, c dbSNP:9273443
1322 1322 a, c dbSNP:545181996
1323 1323 a, c dbSNP:9273442
1332 1332 c, g dbSNP:9273441
1344 1344 a, g dbSNP:9273440
1370 1370 a, c dbSNP:28724234
1370 1370 -, c dbSNP:62998560
1371 1371 a, t dbSNP:9273439
1378 1378 g, t dbSNP:1130451
1382 1382 c, t dbSNP:9273438
1383 1383 -, ca dbSNP:765291761
1383 1383 a, c, g dbSNP:9273437
1388 1388 a, c dbSNP:9273436
1390 1390 g, t dbSNP:1056315
1411 1411 a, g dbSNP:1056316
1412 1412 -, c dbSNP:63031662
1413 1413 -, c dbSNP:9282075
1414 1414 a, c dbSNP:112615708
1416 1416 c, t dbSNP:9273433
1420 1420 a, g dbSNP:9273432
1425 1425 c, t dbSNP:1064173
1445 1445 a, c dbSNP:9273430
1449 1449 c, t dbSNP:9273429
1455 1455 c, t dbSNP:1056318
1459 1459 a, g dbSNP:28724233
1464 1464 g, t dbSNP:9273427
1471 1471 g, t dbSNP:9273426
1487 1487 c, g dbSNP:533116120
1500 1500 c, g dbSNP:1130455
1509 1509 a, g dbSNP:9273425
1511 1511 a, g dbSNP:9273424
1515 1515 a, g dbSNP:9273423
1516 1516 c, t dbSNP:751600196
1519 1519 a, g dbSNP:12918
1526 1526 a, g dbSNP:1130456
1538 1538 a, g dbSNP:1130457
1540 1540 a, g dbSNP:9273419
1543 1543 g, t dbSNP:9273418
1553 1553 c, t dbSNP:9273417
1568 1568 c, g dbSNP:537937592
1573 1573 -, a dbSNP:376622401
1575 1575 -, a dbSNP:34835883
1584 1584 a, c dbSNP:9273416
1595 1595 a, g dbSNP:9273415
1606 1606 a, t dbSNP:9273414
1613 1613 c, t dbSNP:9273413
1642 1642 a, g dbSNP:9273412
1645 1645 c, t dbSNP:9273411
1655 1655 g, t dbSNP:9273410
1663 1663 a, g dbSNP:111951747

Target ORF information:

RefSeq Version NM_001243961
Organism Homo sapiens (human)
Definition Homo sapiens major histocompatibility complex, class II, DQ beta 1 (HLA-DQB1), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001243961

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGTCTTGGA AGAAGGCTTT GCGGATCCCC GGAGACCTTC GGGTAGCAAC TGTCACCTTG 
ATGCTGGCGA TGCTGAGCTC CCTACTGGCT GAGGGCAGAG ACTCTCCCGA GGATTTCGTG
TTCCAGTTTA AGGGCATGTG CTACTTCACC AACGGGACGG AGCGCGTGCG TCTTGTGACC
AGATACATCT ATAACCGAGA GGAGTACGCG CGCTTCGACA GCGACGTGGG GGTGTACCGC
GCGGTGACGC CGCAGGGGCG GCCTGATGCC GAGTACTGGA ACAGCCAGAA GGAAGTCCTG
GAGGGGACCC GGGCGGAGTT GGACACGGTG TGCAGACACA ACTACGAGGT GGCGTTCCGC
GGGATCTTGC AGAGGAGAGT GGAGCCCACA GTGACCATCT CCCCATCCAG GACAGAGGCC
CTCAACCACC ACAACCTGCT GGTCTGCTCG GTGACAGATT TCTATCCAGG CCAGATCAAA
GTCCGGTGGT TTCGGAATGA TCAGGAGGAG ACAGCCGGCG TTGTGTCCAC CCCCCTTATT
AGGAATGGTG ACTGGACTTT CCAGATCCTG GTGATGCTGG AAATGACTCC CCAGCGTGGA
GATGTCTACA CCTGCCACGT GGAGCACCCC AGCCTCCAGA GCCCCATCAC CGTGGAGTGG
CGGGCTCAGT CTGAATCTGC CCAGAGCAAG ATGCTGAGTG GCGTTGGAGG CTTCGTGCTG
GGGCTGATCT TCCTTGGGCT GGGCCTTATC ATCCGTCAAA GGAGTCAGAA AGGACCTCAA
GGGCCTCCAC CAGCAGGGCT TCTGCACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.