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HIST2H2AB cDNA ORF clone, Homo sapiens (human)

Gene Symbol HIST2H2AB
Entrez Gene ID 317772
Full Name histone cluster 2, H2ab
Synonyms H2AB
General protein information
Preferred Names
histone H2A type 2-B
Names
histone H2A type 2-B
histone 2, H2ab
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

1

1q21

Summary Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene contain a palindromic termination element. [provided by RefSeq, Aug 2015]. lac of sum
Disorder MIM:

615014

Disorder Html:





The following HIST2H2AB gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the HIST2H2AB cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu14009 NM_175065 Homo sapiens histone cluster 2, H2ab (HIST2H2AB), mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $99.00

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**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu14009
Accession Version NM_175065.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 393bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 18-AUG-2015
Organism Homo sapiens (human)
Product histone H2A type 2-B
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AY131972.1. On Mar 25, 2003 this sequence version replaced gi:28195393. Summary: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene contain a palindromic termination element. [provided by RefSeq, Aug 2015]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##RefSeq-Attributes-START## replication-dependent histone :: PMID: 12408966 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
ATGTCAGGAC GCGGAAAGCA GGGAGGCAAG GCCCGCGCTA AGGCCAAGTC GCGCTCGTCC 
CGCGCTGGTC TCCAGTTCCC GGTGGGGCGA GTGCACCGCT TGCTGCGCAA AGGCAACTAC
GCGGAGCGGG TCGGGGCAGG CGCCCCGGTG TACCTGGCGG CGGTCCTCGA GTACCTGACC
GCGGAAATTC TGGAGCTGGC GGGCAACGCG GCTCGGGACA ACAAGAAGAC GCGCATCATC
CCTCGCCATC TGCAACTAGC CGTGAGGAAT GACGAAGAGC TCAACAAGTT ACTCGGGGGT
GTCACCATTG CCCAGGGCGG CGTCTTGCCC AATATCCAGG CTGTCCTGTT GCCCAAGAAA
ACGGAGAGTC ACAAGCCTGG CAAGAACAAG TAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqNP_778235.1
CDS1..393
Misc Feature(1)1..390(+)
Misc Feature(2)4..6(+)
Misc Feature(3)4..6(+)
Misc Feature(4)10..12(+)
Misc Feature(5)10..12(+)
Misc Feature(6)16..360(+)
Misc Feature(7)16..30(+)
Misc Feature(8)16..18(+)
Misc Feature(9)88..234(+)
Misc Feature(10)109..111(+)
Misc Feature(11)115..126(+)
Misc Feature(12)154..192(+)
Misc Feature(13)313..315(+)
Misc Feature(14)355..357(+)
Misc Feature(15)358..360(+)
Misc Feature(16)358..360(+)
Misc Feature(17)361..363(+)
Misc Feature(18)367..369(+)
Exon (1)1..448
Gene:HIST2H2AB
Gene Synonym:
Translation
Position Chain Variation Link
137 137 a, c, t dbSNP:200774928
311 311 c, t dbSNP:745933110
394 394 -, ttaa dbSNP:781752502
408 408 a, t dbSNP:12118591

Target ORF information:

RefSeq Version NM_175065
Organism Homo sapiens (human)
Definition Homo sapiens histone cluster 2, H2ab (HIST2H2AB), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_175065

ORF Insert Sequence:

1
61
121
181
241
301
361
ATGTCAGGAC GCGGAAAGCA GGGAGGCAAG GCCCGCGCTA AGGCCAAGTC GCGCTCGTCC 
CGCGCTGGTC TCCAGTTCCC GGTGGGGCGA GTGCACCGCT TGCTGCGCAA AGGCAACTAC
GCGGAGCGGG TCGGGGCAGG CGCCCCGGTG TACCTGGCGG CGGTCCTCGA GTACCTGACC
GCGGAAATTC TGGAGCTGGC GGGCAACGCG GCTCGGGACA ACAAGAAGAC GCGCATCATC
CCTCGCCATC TGCAACTAGC CGTGAGGAAT GACGAAGAGC TCAACAAGTT ACTCGGGGGT
GTCACCATTG CCCAGGGCGG CGTCTTGCCC AATATCCAGG CTGTCCTGTT GCCCAAGAAA
ACGGAGAGTC ACAAGCCTGG CAAGAACAAG TAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

 
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