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APC cDNA ORF clone, Homo sapiens (human)

Gene Symbol APC
Entrez Gene ID 324
Full Name adenomatous polyposis coli
Synonyms BTPS2, DP2, DP2.5, DP3, GS, PPP1R46
General protein information
Preferred Names
adenomatous polyposis coli protein
Names
adenomatous polyposis coli protein
deleted in polyposis 2.5
adenomatosis polyposis coli tumor suppressor
protein phosphatase 1, regulatory subunit 46
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

5

5q21-q22

Summary This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

611731

Disorder Html: Adenomatous polyposis coli, 175100 (3); Gastric cancer, somatic,

mRNA and Protein(s)

mRNA Protein Name
NM_000038 NP_000029 adenomatous polyposis coli protein isoform b
NM_001127511 NP_001120983 adenomatous polyposis coli protein isoform a
NM_001127510 NP_001120982 adenomatous polyposis coli protein isoform b



Homo sapiens (human) APC NP_001120982.1
Pan troglodytes (chimpanzee) APC XP_001143965.1
Canis lupus familiaris (dog) APC XP_005618091.1
Bos taurus (cattle) APC NP_001069454.2
Mus musculus (house mouse) Apc NP_031488.2
Rattus norvegicus (Norway rat) Apc NP_036631.1
Gallus gallus (chicken) APC XP_004949340.1
Danio rerio (zebrafish) apc NP_001137312.1
Xenopus (Silurana) tropicalis (western clawed frog) apc XP_004910521.1


GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following APC gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the APC cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu16786 NM_000038 Homo sapiens adenomatous polyposis coli (APC), transcript variant 3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 24 $923.30
$1319.00
OHu16843 NM_001127511 Homo sapiens adenomatous polyposis coli (APC), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $923.30
$1319.00
OHu16786 NM_001127510 Homo sapiens adenomatous polyposis coli (APC), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 24 $923.30
$1319.00
Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
5 or more Clone 50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu16786
Clone ID Related Accession (Same CDS sequence) NM_000038 , NM_001127510
Accession Version NM_000038.5 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 8532bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 21-MAY-2015
Organism Homo sapiens (human)
Product adenomatous polyposis coli protein isoform b
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA795663.1, M73548.1, AB210001.1 and CA313732.1. On Sep 17, 2010 this sequence version replaced gi:189011564. Transcript Variant: This variant (3) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. This variant also contains an alternate in-frame exon compared to variant 1. The encoded isoform (b) has a distinct N-terminus and is longer than isoform a. Variants 2 and 3 encode the same isoform (b). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M73548.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
3481
3541
3601
3661
3721
3781
3841
3901
3961
4021
4081
4141
4201
4261
4321
4381
4441
4501
4561
4621
4681
4741
4801
4861
4921
4981
5041
5101
5161
5221
5281
5341
5401
5461
5521
5581
5641
5701
5761
5821
5881
5941
6001
6061
6121
6181
6241
6301
6361
6421
6481
6541
6601
6661
6721
6781
6841
6901
6961
7021
7081
7141
7201
7261
7321
7381
7441
7501
7561
7621
7681
7741
7801
7861
7921
7981
8041
8101
8161
8221
8281
8341
8401
8461
8521
ATGGCTGCAG CTTCATATGA TCAGTTGTTA AAGCAAGTTG AGGCACTGAA GATGGAGAAC 
TCAAATCTTC GACAAGAGCT AGAAGATAAT TCCAATCATC TTACAAAACT GGAAACTGAG
GCATCTAATA TGAAGGAAGT ACTTAAACAA CTACAAGGAA GTATTGAAGA TGAAGCTATG
GCTTCTTCTG GACAGATTGA TTTATTAGAG CGTCTTAAAG AGCTTAACTT AGATAGCAGT
AATTTCCCTG GAGTAAAACT GCGGTCAAAA ATGTCCCTCC GTTCTTATGG AAGCCGGGAA
GGATCTGTAT CAAGCCGTTC TGGAGAGTGC AGTCCTGTTC CTATGGGTTC ATTTCCAAGA
AGAGGGTTTG TAAATGGAAG CAGAGAAAGT ACTGGATATT TAGAAGAACT TGAGAAAGAG
AGGTCATTGC TTCTTGCTGA TCTTGACAAA GAAGAAAAGG AAAAAGACTG GTATTACGCT
CAACTTCAGA ATCTCACTAA AAGAATAGAT AGTCTTCCTT TAACTGAAAA TTTTTCCTTA
CAAACAGATA TGACCAGAAG GCAATTGGAA TATGAAGCAA GGCAAATCAG AGTTGCGATG
GAAGAACAAC TAGGTACCTG CCAGGATATG GAAAAACGAG CACAGCGAAG AATAGCCAGA
ATTCAGCAAA TCGAAAAGGA CATACTTCGT ATACGACAGC TTTTACAGTC CCAAGCAACA
GAAGCAGAGA GGTCATCTCA GAACAAGCAT GAAACCGGCT CACATGATGC TGAGCGGCAG
AATGAAGGTC AAGGAGTGGG AGAAATCAAC ATGGCAACTT CTGGTAATGG TCAGGGTTCA
ACTACACGAA TGGACCATGA AACAGCCAGT GTTTTGAGTT CTAGTAGCAC ACACTCTGCA
CCTCGAAGGC TGACAAGTCA TCTGGGAACC AAGGTGGAAA TGGTGTATTC ATTGTTGTCA
ATGCTTGGTA CTCATGATAA GGATGATATG TCGCGAACTT TGCTAGCTAT GTCTAGCTCC
CAAGACAGCT GTATATCCAT GCGACAGTCT GGATGTCTTC CTCTCCTCAT CCAGCTTTTA
CATGGCAATG ACAAAGACTC TGTATTGTTG GGAAATTCCC GGGGCAGTAA AGAGGCTCGG
GCCAGGGCCA GTGCAGCACT CCACAACATC ATTCACTCAC AGCCTGATGA CAAGAGAGGC
AGGCGTGAAA TCCGAGTCCT TCATCTTTTG GAACAGATAC GCGCTTACTG TGAAACCTGT
TGGGAGTGGC AGGAAGCTCA TGAACCAGGC ATGGACCAGG ACAAAAATCC AATGCCAGCT
CCTGTTGAAC ATCAGATCTG TCCTGCTGTG TGTGTTCTAA TGAAACTTTC ATTTGATGAA
GAGCATAGAC ATGCAATGAA TGAACTAGGG GGACTACAGG CCATTGCAGA ATTATTGCAA
GTGGACTGTG AAATGTATGG GCTTACTAAT GACCACTACA GTATTACACT AAGACGATAT
GCTGGAATGG CTTTGACAAA CTTGACTTTT GGAGATGTAG CCAACAAGGC TACGCTATGC
TCTATGAAAG GCTGCATGAG AGCACTTGTG GCCCAACTAA AATCTGAAAG TGAAGACTTA
CAGCAGGTTA TTGCGAGTGT TTTGAGGAAT TTGTCTTGGC GAGCAGATGT AAATAGTAAA
AAGACGTTGC GAGAAGTTGG AAGTGTGAAA GCATTGATGG AATGTGCTTT AGAAGTTAAA
AAGGAATCAA CCCTCAAAAG CGTATTGAGT GCCTTATGGA ATTTGTCAGC ACATTGCACT
GAGAATAAAG CTGATATATG TGCTGTAGAT GGTGCACTTG CATTTTTGGT TGGCACTCTT
ACTTACCGGA GCCAGACAAA CACTTTAGCC ATTATTGAAA GTGGAGGTGG GATATTACGG
AATGTGTCCA GCTTGATAGC TACAAATGAG GACCACAGGC AAATCCTAAG AGAGAACAAC
TGTCTACAAA CTTTATTACA ACACTTAAAA TCTCATAGTT TGACAATAGT CAGTAATGCA
TGTGGAACTT TGTGGAATCT CTCAGCAAGA AATCCTAAAG ACCAGGAAGC ATTATGGGAC
ATGGGGGCAG TTAGCATGCT CAAGAACCTC ATTCATTCAA AGCACAAAAT GATTGCTATG
GGAAGTGCTG CAGCTTTAAG GAATCTCATG GCAAATAGGC CTGCGAAGTA CAAGGATGCC
AATATTATGT CTCCTGGCTC AAGCTTGCCA TCTCTTCATG TTAGGAAACA AAAAGCCCTA
GAAGCAGAAT TAGATGCTCA GCACTTATCA GAAACTTTTG ACAATATAGA CAATTTAAGT
CCCAAGGCAT CTCATCGTAG TAAGCAGAGA CACAAGCAAA GTCTCTATGG TGATTATGTT
TTTGACACCA ATCGACATGA TGATAATAGG TCAGACAATT TTAATACTGG CAACATGACT
GTCCTTTCAC CATATTTGAA TACTACAGTG TTACCCAGCT CCTCTTCATC AAGAGGAAGC
TTAGATAGTT CTCGTTCTGA AAAAGATAGA AGTTTGGAGA GAGAACGCGG AATTGGTCTA
GGCAACTACC ATCCAGCAAC AGAAAATCCA GGAACTTCTT CAAAGCGAGG TTTGCAGATC
TCCACCACTG CAGCCCAGAT TGCCAAAGTC ATGGAAGAAG TGTCAGCCAT TCATACCTCT
CAGGAAGACA GAAGTTCTGG GTCTACCACT GAATTACATT GTGTGACAGA TGAGAGAAAT
GCACTTAGAA GAAGCTCTGC TGCCCATACA CATTCAAACA CTTACAATTT CACTAAGTCG
GAAAATTCAA ATAGGACATG TTCTATGCCT TATGCCAAAT TAGAATACAA GAGATCTTCA
AATGATAGTT TAAATAGTGT CAGTAGTAGT GATGGTTATG GTAAAAGAGG TCAAATGAAA
CCCTCGATTG AATCCTATTC TGAAGATGAT GAAAGTAAGT TTTGCAGTTA TGGTCAATAC
CCAGCCGACC TAGCCCATAA AATACATAGT GCAAATCATA TGGATGATAA TGATGGAGAA
CTAGATACAC CAATAAATTA TAGTCTTAAA TATTCAGATG AGCAGTTGAA CTCTGGAAGG
CAAAGTCCTT CACAGAATGA AAGATGGGCA AGACCCAAAC ACATAATAGA AGATGAAATA
AAACAAAGTG AGCAAAGACA ATCAAGGAAT CAAAGTACAA CTTATCCTGT TTATACTGAG
AGCACTGATG ATAAACACCT CAAGTTCCAA CCACATTTTG GACAGCAGGA ATGTGTTTCT
CCATACAGGT CACGGGGAGC CAATGGTTCA GAAACAAATC GAGTGGGTTC TAATCATGGA
ATTAATCAAA ATGTAAGCCA GTCTTTGTGT CAAGAAGATG ACTATGAAGA TGATAAGCCT
ACCAATTATA GTGAACGTTA CTCTGAAGAA GAACAGCATG AAGAAGAAGA GAGACCAACA
AATTATAGCA TAAAATATAA TGAAGAGAAA CGTCATGTGG ATCAGCCTAT TGATTATAGT
TTAAAATATG CCACAGATAT TCCTTCATCA CAGAAACAGT CATTTTCATT CTCAAAGAGT
TCATCTGGAC AAAGCAGTAA AACCGAACAT ATGTCTTCAA GCAGTGAGAA TACGTCCACA
CCTTCATCTA ATGCCAAGAG GCAGAATCAG CTCCATCCAA GTTCTGCACA GAGTAGAAGT
GGTCAGCCTC AAAAGGCTGC CACTTGCAAA GTTTCTTCTA TTAACCAAGA AACAATACAG
ACTTATTGTG TAGAAGATAC TCCAATATGT TTTTCAAGAT GTAGTTCATT ATCATCTTTG
TCATCAGCTG AAGATGAAAT AGGATGTAAT CAGACGACAC AGGAAGCAGA TTCTGCTAAT
ACCCTGCAAA TAGCAGAAAT AAAAGAAAAG ATTGGAACTA GGTCAGCTGA AGATCCTGTG
AGCGAAGTTC CAGCAGTGTC ACAGCACCCT AGAACCAAAT CCAGCAGACT GCAGGGTTCT
AGTTTATCTT CAGAATCAGC CAGGCACAAA GCTGTTGAAT TTTCTTCAGG AGCGAAATCT
CCCTCCAAAA GTGGTGCTCA GACACCCAAA AGTCCACCTG AACACTATGT TCAGGAGACC
CCACTCATGT TTAGCAGATG TACTTCTGTC AGTTCACTTG ATAGTTTTGA GAGTCGTTCG
ATTGCCAGCT CCGTTCAGAG TGAACCATGC AGTGGAATGG TAAGTGGCAT TATAAGCCCC
AGTGATCTTC CAGATAGCCC TGGACAAACC ATGCCACCAA GCAGAAGTAA AACACCTCCA
CCACCTCCTC AAACAGCTCA AACCAAGCGA GAAGTACCTA AAAATAAAGC ACCTACTGCT
GAAAAGAGAG AGAGTGGACC TAAGCAAGCT GCAGTAAATG CTGCAGTTCA GAGGGTCCAG
GTTCTTCCAG ATGCTGATAC TTTATTACAT TTTGCCACGG AAAGTACTCC AGATGGATTT
TCTTGTTCAT CCAGCCTGAG TGCTCTGAGC CTCGATGAGC CATTTATACA GAAAGATGTG
GAATTAAGAA TAATGCCTCC AGTTCAGGAA AATGACAATG GGAATGAAAC AGAATCAGAG
CAGCCTAAAG AATCAAATGA AAACCAAGAG AAAGAGGCAG AAAAAACTAT TGATTCTGAA
AAGGACCTAT TAGATGATTC AGATGATGAT GATATTGAAA TACTAGAAGA ATGTATTATT
TCTGCCATGC CAACAAAGTC ATCACGTAAA GCAAAAAAGC CAGCCCAGAC TGCTTCAAAA
TTACCTCCAC CTGTGGCAAG GAAACCAAGT CAGCTGCCTG TGTACAAACT TCTACCATCA
CAAAACAGGT TGCAACCCCA AAAGCATGTT AGTTTTACAC CGGGGGATGA TATGCCACGG
GTGTATTGTG TTGAAGGGAC ACCTATAAAC TTTTCCACAG CTACATCTCT AAGTGATCTA
ACAATCGAAT CCCCTCCAAA TGAGTTAGCT GCTGGAGAAG GAGTTAGAGG AGGGGCACAG
TCAGGTGAAT TTGAAAAACG AGATACCATT CCTACAGAAG GCAGAAGTAC AGATGAGGCT
CAAGGAGGAA AAACCTCATC TGTAACCATA CCTGAATTGG ATGACAATAA AGCAGAGGAA
GGTGATATTC TTGCAGAATG CATTAATTCT GCTATGCCCA AAGGGAAAAG TCACAAGCCT
TTCCGTGTGA AAAAGATAAT GGACCAGGTC CAGCAAGCAT CTGCGTCTTC TTCTGCACCC
AACAAAAATC AGTTAGATGG TAAGAAAAAG AAACCAACTT CACCAGTAAA ACCTATACCA
CAAAATACTG AATATAGGAC ACGTGTAAGA AAAAATGCAG ACTCAAAAAA TAATTTAAAT
GCTGAGAGAG TTTTCTCAGA CAACAAAGAT TCAAAGAAAC AGAATTTGAA AAATAATTCC
AAGGTCTTCA ATGATAAGCT CCCAAATAAT GAAGATAGAG TCAGAGGAAG TTTTGCTTTT
GATTCACCTC ATCATTACAC GCCTATTGAA GGAACTCCTT ACTGTTTTTC ACGAAATGAT
TCTTTGAGTT CTCTAGATTT TGATGATGAT GATGTTGACC TTTCCAGGGA AAAGGCTGAA
TTAAGAAAGG CAAAAGAAAA TAAGGAATCA GAGGCTAAAG TTACCAGCCA CACAGAACTA
ACCTCCAACC AACAATCAGC TAATAAGACA CAAGCTATTG CAAAGCAGCC AATAAATCGA
GGTCAGCCTA AACCCATACT TCAGAAACAA TCCACTTTTC CCCAGTCATC CAAAGACATA
CCAGACAGAG GGGCAGCAAC TGATGAAAAG TTACAGAATT TTGCTATTGA AAATACTCCG
GTTTGCTTTT CTCATAATTC CTCTCTGAGT TCTCTCAGTG ACATTGACCA AGAAAACAAC
AATAAAGAAA ATGAACCTAT CAAAGAGACT GAGCCCCCTG ACTCACAGGG AGAACCAAGT
AAACCTCAAG CATCAGGCTA TGCTCCTAAA TCATTTCATG TTGAAGATAC CCCAGTTTGT
TTCTCAAGAA ACAGTTCTCT CAGTTCTCTT AGTATTGACT CTGAAGATGA CCTGTTGCAG
GAATGTATAA GCTCCGCAAT GCCAAAAAAG AAAAAGCCTT CAAGACTCAA GGGTGATAAT
GAAAAACATA GTCCCAGAAA TATGGGTGGC ATATTAGGTG AAGATCTGAC ACTTGATTTG
AAAGATATAC AGAGACCAGA TTCAGAACAT GGTCTATCCC CTGATTCAGA AAATTTTGAT
TGGAAAGCTA TTCAGGAAGG TGCAAATTCC ATAGTAAGTA GTTTACATCA AGCTGCTGCT
GCTGCATGTT TATCTAGACA AGCTTCGTCT GATTCAGATT CCATCCTTTC CCTGAAATCA
GGAATCTCTC TGGGATCACC ATTTCATCTT ACACCTGATC AAGAAGAAAA ACCCTTTACA
AGTAATAAAG GCCCACGAAT TCTAAAACCA GGGGAGAAAA GTACATTGGA AACTAAAAAG
ATAGAATCTG AAAGTAAAGG AATCAAAGGA GGAAAAAAAG TTTATAAAAG TTTGATTACT
GGAAAAGTTC GATCTAATTC AGAAATTTCA GGCCAAATGA AACAGCCCCT TCAAGCAAAC
ATGCCTTCAA TCTCTCGAGG CAGGACAATG ATTCATATTC CAGGAGTTCG AAATAGCTCC
TCAAGTACAA GTCCTGTTTC TAAAAAAGGC CCACCCCTTA AGACTCCAGC CTCCAAAAGC
CCTAGTGAAG GTCAAACAGC CACCACTTCT CCTAGAGGAG CCAAGCCATC TGTGAAATCA
GAATTAAGCC CTGTTGCCAG GCAGACATCC CAAATAGGTG GGTCAAGTAA AGCACCTTCT
AGATCAGGAT CTAGAGATTC GACCCCTTCA AGACCTGCCC AGCAACCATT AAGTAGACCT
ATACAGTCTC CTGGCCGAAA CTCAATTTCC CCTGGTAGAA ATGGAATAAG TCCTCCTAAC
AAATTATCTC AACTTCCAAG GACATCATCC CCTAGTACTG CTTCAACTAA GTCCTCAGGT
TCTGGAAAAA TGTCATATAC ATCTCCAGGT AGACAGATGA GCCAACAGAA CCTTACCAAA
CAAACAGGTT TATCCAAGAA TGCCAGTAGT ATTCCAAGAA GTGAGTCTGC CTCCAAAGGA
CTAAATCAGA TGAATAATGG TAATGGAGCC AATAAAAAGG TAGAACTTTC TAGAATGTCT
TCAACTAAAT CAAGTGGAAG TGAATCTGAT AGATCAGAAA GACCTGTATT AGTACGCCAG
TCAACTTTCA TCAAAGAAGC TCCAAGCCCA ACCTTAAGAA GAAAATTGGA GGAATCTGCT
TCATTTGAAT CTCTTTCTCC ATCATCTAGA CCAGCTTCTC CCACTAGGTC CCAGGCACAA
ACTCCAGTTT TAAGTCCTTC CCTTCCTGAT ATGTCTCTAT CCACACATTC GTCTGTTCAG
GCTGGTGGAT GGCGAAAACT CCCACCTAAT CTCAGTCCCA CTATAGAGTA TAATGATGGA
AGACCAGCAA AGCGCCATGA TATTGCACGG TCTCATTCTG AAAGTCCTTC TAGACTTCCA
ATCAATAGGT CAGGAACCTG GAAACGTGAG CACAGCAAAC ATTCATCATC CCTTCCTCGA
GTAAGCACTT GGAGAAGAAC TGGAAGTTCA TCTTCAATTC TTTCTGCTTC ATCAGAATCC
AGTGAAAAAG CAAAAAGTGA GGATGAAAAA CATGTGAACT CTATTTCAGG AACCAAACAA
AGTAAAGAAA ACCAAGTATC CGCAAAAGGA ACATGGAGAA AAATAAAAGA AAATGAATTT
TCTCCCACAA ATAGTACTTC TCAGACCGTT TCCTCAGGTG CTACAAATGG TGCTGAATCA
AAGACTCTAA TTTATCAAAT GGCACCTGCT GTTTCTAAAA CAGAGGATGT TTGGGTGAGA
ATTGAGGACT GTCCCATTAA CAATCCTAGA TCTGGAAGAT CTCCCACAGG TAATACTCCC
CCGGTGATTG ACAGTGTTTC AGAAAAGGCA AATCCAAACA TTAAAGATTC AAAAGATAAT
CAGGCAAAAC AAAATGTGGG TAATGGCAGT GTTCCCATGC GTACCGTGGG TTTGGAAAAT
CGCCTGAACT CCTTTATTCA GGTGGATGCC CCTGACCAAA AAGGAACTGA GATAAAACCA
GGACAAAATA ATCCTGTCCC TGTATCAGAG ACTAATGAAA GTTCTATAGT GGAACGTACC
CCATTCAGTT CTAGCAGCTC AAGCAAACAC AGTTCACCTA GTGGGACTGT TGCTGCCAGA
GTGACTCCTT TTAATTACAA CCCAAGCCCT AGGAAAAGCA GCGCAGATAG CACTTCAGCT
CGGCCATCTC AGATCCCAAC TCCAGTGAAT AACAACACAA AGAAGCGAGA TTCCAAAACT
GACAGCACAG AATCCAGTGG AACCCAAAGT CCTAAGCGCC ATTCTGGGTC TTACCTTGTG
ACATCTGTTT AA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_000029.2
CDS86..8617
Misc Feature(1)77..79(+)
Misc Feature(2)89..91(+)
Misc Feature(3)461..709(+)
Misc Feature(4)1016..1324(+)
Misc Feature(5)1076..1252(+)
Misc Feature(6)1442..1570(+)
Misc Feature(7)1475..1876(+)
Misc Feature(8)1580..1876(+)
Misc Feature(9)1598..1726(+)
Misc Feature(10)1727..1858(+)
Misc Feature(11)1859..1999(+)
Misc Feature(12)1916..2278(+)
Misc Feature(13)1982..2278(+)
Misc Feature(14)2000..2134(+)
Misc Feature(15)2135..2260(+)
Misc Feature(16)2249..2251(+)
Misc Feature(17)2261..2386(+)
Misc Feature(18)2315..2317(+)
Misc Feature(19)2423..2425(+)
Misc Feature(20)2963..4096(+)
Misc Feature(21)3209..3211(+)
Misc Feature(22)3920..3922(+)
Misc Feature(23)4163..4165(+)
Misc Feature(24)4190..4267(+)
Misc Feature(25)4259..4261(+)
Misc Feature(26)4586..4588(+)
Misc Feature(27)4592..4594(+)
Misc Feature(28)4595..4597(+)
Misc Feature(29)4598..4600(+)
Misc Feature(30)4604..4606(+)
Misc Feature(31)4613..4615(+)
Misc Feature(32)4991..5068(+)
Misc Feature(33)5240..5299(+)
Misc Feature(34)5666..5668(+)
Misc Feature(35)5666..5668(+)
Misc Feature(36)5672..5674(+)
Misc Feature(37)5672..5674(+)
Misc Feature(38)5675..5677(+)
Misc Feature(39)5675..5677(+)
Misc Feature(40)5681..5764(+)
Misc Feature(41)6185..6244(+)
Misc Feature(42)6245..6247(+)
Misc Feature(43)6362..6364(+)
Misc Feature(44)6536..6538(+)
Misc Feature(45)6752..7789(+)
Misc Feature(46)6863..6865(+)
Misc Feature(47)6893..6895(+)
Misc Feature(48)6932..6934(+)
Misc Feature(49)7277..7279(+)
Misc Feature(50)7502..7504(+)
Misc Feature(51)7688..7690(+)
Misc Feature(52)8093..8614(+)
Misc Feature(53)8096..8098(+)
Misc Feature(54)8105..8107(+)
Misc Feature(55)8120..8122(+)
Misc Feature(56)8450..8452(+)
Misc Feature(57)8492..8503(+)
Misc Feature(58)8606..8614(+)
Exon (1)1..67
Gene:APC
Gene Synonym:
Exon (2)68..220
Gene:APC
Gene Synonym:
Exon (3)221..305
Gene:APC
Gene Synonym:
Exon (4)306..507
Gene:APC
Gene Synonym:
Exon (5)508..616
Gene:APC
Gene Synonym:
Exon (6)617..730
Gene:APC
Gene Synonym:
Exon (7)731..814
Gene:APC
Gene Synonym:
Exon (8)815..919
Gene:APC
Gene Synonym:
Exon (9)920..1018
Gene:APC
Gene Synonym:
Exon (10)1019..1397
Gene:APC
Gene Synonym:
Exon (11)1398..1493
Gene:APC
Gene Synonym:
Exon (12)1494..1633
Gene:APC
Gene Synonym:
Exon (13)1634..1711
Gene:APC
Gene Synonym:
Exon (14)1712..1828
Gene:APC
Gene Synonym:
Exon (15)1829..2043
Gene:APC
Gene Synonym:
Exon (16)2044..10730
Gene:APC
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_000038
Organism Homo sapiens (human)
Definition Homo sapiens adenomatous polyposis coli (APC), transcript variant 3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_000038

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
3481
3541
3601
3661
3721
3781
3841
3901
3961
4021
4081
4141
4201
4261
4321
4381
4441
4501
4561
4621
4681
4741
4801
4861
4921
4981
5041
5101
5161
5221
5281
5341
5401
5461
5521
5581
5641
5701
5761
5821
5881
5941
6001
6061
6121
6181
6241
6301
6361
6421
6481
6541
6601
6661
6721
6781
6841
6901
6961
7021
7081
7141
7201
7261
7321
7381
7441
7501
7561
7621
7681
7741
7801
7861
7921
7981
8041
8101
8161
8221
8281
8341
8401
8461
8521
ATGGCTGCAG CTTCATATGA TCAGTTGTTA AAGCAAGTTG AGGCACTGAA GATGGAGAAC 
TCAAATCTTC GACAAGAGCT AGAAGATAAT TCCAATCATC TTACAAAACT GGAAACTGAG
GCATCTAATA TGAAGGAAGT ACTTAAACAA CTACAAGGAA GTATTGAAGA TGAAGCTATG
GCTTCTTCTG GACAGATTGA TTTATTAGAG CGTCTTAAAG AGCTTAACTT AGATAGCAGT
AATTTCCCTG GAGTAAAACT GCGGTCAAAA ATGTCCCTCC GTTCTTATGG AAGCCGGGAA
GGATCTGTAT CAAGCCGTTC TGGAGAGTGC AGTCCTGTTC CTATGGGTTC ATTTCCAAGA
AGAGGGTTTG TAAATGGAAG CAGAGAAAGT ACTGGATATT TAGAAGAACT TGAGAAAGAG
AGGTCATTGC TTCTTGCTGA TCTTGACAAA GAAGAAAAGG AAAAAGACTG GTATTACGCT
CAACTTCAGA ATCTCACTAA AAGAATAGAT AGTCTTCCTT TAACTGAAAA TTTTTCCTTA
CAAACAGATA TGACCAGAAG GCAATTGGAA TATGAAGCAA GGCAAATCAG AGTTGCGATG
GAAGAACAAC TAGGTACCTG CCAGGATATG GAAAAACGAG CACAGCGAAG AATAGCCAGA
ATTCAGCAAA TCGAAAAGGA CATACTTCGT ATACGACAGC TTTTACAGTC CCAAGCAACA
GAAGCAGAGA GGTCATCTCA GAACAAGCAT GAAACCGGCT CACATGATGC TGAGCGGCAG
AATGAAGGTC AAGGAGTGGG AGAAATCAAC ATGGCAACTT CTGGTAATGG TCAGGGTTCA
ACTACACGAA TGGACCATGA AACAGCCAGT GTTTTGAGTT CTAGTAGCAC ACACTCTGCA
CCTCGAAGGC TGACAAGTCA TCTGGGAACC AAGGTGGAAA TGGTGTATTC ATTGTTGTCA
ATGCTTGGTA CTCATGATAA GGATGATATG TCGCGAACTT TGCTAGCTAT GTCTAGCTCC
CAAGACAGCT GTATATCCAT GCGACAGTCT GGATGTCTTC CTCTCCTCAT CCAGCTTTTA
CATGGCAATG ACAAAGACTC TGTATTGTTG GGAAATTCCC GGGGCAGTAA AGAGGCTCGG
GCCAGGGCCA GTGCAGCACT CCACAACATC ATTCACTCAC AGCCTGATGA CAAGAGAGGC
AGGCGTGAAA TCCGAGTCCT TCATCTTTTG GAACAGATAC GCGCTTACTG TGAAACCTGT
TGGGAGTGGC AGGAAGCTCA TGAACCAGGC ATGGACCAGG ACAAAAATCC AATGCCAGCT
CCTGTTGAAC ATCAGATCTG TCCTGCTGTG TGTGTTCTAA TGAAACTTTC ATTTGATGAA
GAGCATAGAC ATGCAATGAA TGAACTAGGG GGACTACAGG CCATTGCAGA ATTATTGCAA
GTGGACTGTG AAATGTATGG GCTTACTAAT GACCACTACA GTATTACACT AAGACGATAT
GCTGGAATGG CTTTGACAAA CTTGACTTTT GGAGATGTAG CCAACAAGGC TACGCTATGC
TCTATGAAAG GCTGCATGAG AGCACTTGTG GCCCAACTAA AATCTGAAAG TGAAGACTTA
CAGCAGGTTA TTGCGAGTGT TTTGAGGAAT TTGTCTTGGC GAGCAGATGT AAATAGTAAA
AAGACGTTGC GAGAAGTTGG AAGTGTGAAA GCATTGATGG AATGTGCTTT AGAAGTTAAA
AAGGAATCAA CCCTCAAAAG CGTATTGAGT GCCTTATGGA ATTTGTCAGC ACATTGCACT
GAGAATAAAG CTGATATATG TGCTGTAGAT GGTGCACTTG CATTTTTGGT TGGCACTCTT
ACTTACCGGA GCCAGACAAA CACTTTAGCC ATTATTGAAA GTGGAGGTGG GATATTACGG
AATGTGTCCA GCTTGATAGC TACAAATGAG GACCACAGGC AAATCCTAAG AGAGAACAAC
TGTCTACAAA CTTTATTACA ACACTTAAAA TCTCATAGTT TGACAATAGT CAGTAATGCA
TGTGGAACTT TGTGGAATCT CTCAGCAAGA AATCCTAAAG ACCAGGAAGC ATTATGGGAC
ATGGGGGCAG TTAGCATGCT CAAGAACCTC ATTCATTCAA AGCACAAAAT GATTGCTATG
GGAAGTGCTG CAGCTTTAAG GAATCTCATG GCAAATAGGC CTGCGAAGTA CAAGGATGCC
AATATTATGT CTCCTGGCTC AAGCTTGCCA TCTCTTCATG TTAGGAAACA AAAAGCCCTA
GAAGCAGAAT TAGATGCTCA GCACTTATCA GAAACTTTTG ACAATATAGA CAATTTAAGT
CCCAAGGCAT CTCATCGTAG TAAGCAGAGA CACAAGCAAA GTCTCTATGG TGATTATGTT
TTTGACACCA ATCGACATGA TGATAATAGG TCAGACAATT TTAATACTGG CAACATGACT
GTCCTTTCAC CATATTTGAA TACTACAGTG TTACCCAGCT CCTCTTCATC AAGAGGAAGC
TTAGATAGTT CTCGTTCTGA AAAAGATAGA AGTTTGGAGA GAGAACGCGG AATTGGTCTA
GGCAACTACC ATCCAGCAAC AGAAAATCCA GGAACTTCTT CAAAGCGAGG TTTGCAGATC
TCCACCACTG CAGCCCAGAT TGCCAAAGTC ATGGAAGAAG TGTCAGCCAT TCATACCTCT
CAGGAAGACA GAAGTTCTGG GTCTACCACT GAATTACATT GTGTGACAGA TGAGAGAAAT
GCACTTAGAA GAAGCTCTGC TGCCCATACA CATTCAAACA CTTACAATTT CACTAAGTCG
GAAAATTCAA ATAGGACATG TTCTATGCCT TATGCCAAAT TAGAATACAA GAGATCTTCA
AATGATAGTT TAAATAGTGT CAGTAGTAGT GATGGTTATG GTAAAAGAGG TCAAATGAAA
CCCTCGATTG AATCCTATTC TGAAGATGAT GAAAGTAAGT TTTGCAGTTA TGGTCAATAC
CCAGCCGACC TAGCCCATAA AATACATAGT GCAAATCATA TGGATGATAA TGATGGAGAA
CTAGATACAC CAATAAATTA TAGTCTTAAA TATTCAGATG AGCAGTTGAA CTCTGGAAGG
CAAAGTCCTT CACAGAATGA AAGATGGGCA AGACCCAAAC ACATAATAGA AGATGAAATA
AAACAAAGTG AGCAAAGACA ATCAAGGAAT CAAAGTACAA CTTATCCTGT TTATACTGAG
AGCACTGATG ATAAACACCT CAAGTTCCAA CCACATTTTG GACAGCAGGA ATGTGTTTCT
CCATACAGGT CACGGGGAGC CAATGGTTCA GAAACAAATC GAGTGGGTTC TAATCATGGA
ATTAATCAAA ATGTAAGCCA GTCTTTGTGT CAAGAAGATG ACTATGAAGA TGATAAGCCT
ACCAATTATA GTGAACGTTA CTCTGAAGAA GAACAGCATG AAGAAGAAGA GAGACCAACA
AATTATAGCA TAAAATATAA TGAAGAGAAA CGTCATGTGG ATCAGCCTAT TGATTATAGT
TTAAAATATG CCACAGATAT TCCTTCATCA CAGAAACAGT CATTTTCATT CTCAAAGAGT
TCATCTGGAC AAAGCAGTAA AACCGAACAT ATGTCTTCAA GCAGTGAGAA TACGTCCACA
CCTTCATCTA ATGCCAAGAG GCAGAATCAG CTCCATCCAA GTTCTGCACA GAGTAGAAGT
GGTCAGCCTC AAAAGGCTGC CACTTGCAAA GTTTCTTCTA TTAACCAAGA AACAATACAG
ACTTATTGTG TAGAAGATAC TCCAATATGT TTTTCAAGAT GTAGTTCATT ATCATCTTTG
TCATCAGCTG AAGATGAAAT AGGATGTAAT CAGACGACAC AGGAAGCAGA TTCTGCTAAT
ACCCTGCAAA TAGCAGAAAT AAAAGAAAAG ATTGGAACTA GGTCAGCTGA AGATCCTGTG
AGCGAAGTTC CAGCAGTGTC ACAGCACCCT AGAACCAAAT CCAGCAGACT GCAGGGTTCT
AGTTTATCTT CAGAATCAGC CAGGCACAAA GCTGTTGAAT TTTCTTCAGG AGCGAAATCT
CCCTCCAAAA GTGGTGCTCA GACACCCAAA AGTCCACCTG AACACTATGT TCAGGAGACC
CCACTCATGT TTAGCAGATG TACTTCTGTC AGTTCACTTG ATAGTTTTGA GAGTCGTTCG
ATTGCCAGCT CCGTTCAGAG TGAACCATGC AGTGGAATGG TAAGTGGCAT TATAAGCCCC
AGTGATCTTC CAGATAGCCC TGGACAAACC ATGCCACCAA GCAGAAGTAA AACACCTCCA
CCACCTCCTC AAACAGCTCA AACCAAGCGA GAAGTACCTA AAAATAAAGC ACCTACTGCT
GAAAAGAGAG AGAGTGGACC TAAGCAAGCT GCAGTAAATG CTGCAGTTCA GAGGGTCCAG
GTTCTTCCAG ATGCTGATAC TTTATTACAT TTTGCCACGG AAAGTACTCC AGATGGATTT
TCTTGTTCAT CCAGCCTGAG TGCTCTGAGC CTCGATGAGC CATTTATACA GAAAGATGTG
GAATTAAGAA TAATGCCTCC AGTTCAGGAA AATGACAATG GGAATGAAAC AGAATCAGAG
CAGCCTAAAG AATCAAATGA AAACCAAGAG AAAGAGGCAG AAAAAACTAT TGATTCTGAA
AAGGACCTAT TAGATGATTC AGATGATGAT GATATTGAAA TACTAGAAGA ATGTATTATT
TCTGCCATGC CAACAAAGTC ATCACGTAAA GCAAAAAAGC CAGCCCAGAC TGCTTCAAAA
TTACCTCCAC CTGTGGCAAG GAAACCAAGT CAGCTGCCTG TGTACAAACT TCTACCATCA
CAAAACAGGT TGCAACCCCA AAAGCATGTT AGTTTTACAC CGGGGGATGA TATGCCACGG
GTGTATTGTG TTGAAGGGAC ACCTATAAAC TTTTCCACAG CTACATCTCT AAGTGATCTA
ACAATCGAAT CCCCTCCAAA TGAGTTAGCT GCTGGAGAAG GAGTTAGAGG AGGGGCACAG
TCAGGTGAAT TTGAAAAACG AGATACCATT CCTACAGAAG GCAGAAGTAC AGATGAGGCT
CAAGGAGGAA AAACCTCATC TGTAACCATA CCTGAATTGG ATGACAATAA AGCAGAGGAA
GGTGATATTC TTGCAGAATG CATTAATTCT GCTATGCCCA AAGGGAAAAG TCACAAGCCT
TTCCGTGTGA AAAAGATAAT GGACCAGGTC CAGCAAGCAT CTGCGTCTTC TTCTGCACCC
AACAAAAATC AGTTAGATGG TAAGAAAAAG AAACCAACTT CACCAGTAAA ACCTATACCA
CAAAATACTG AATATAGGAC ACGTGTAAGA AAAAATGCAG ACTCAAAAAA TAATTTAAAT
GCTGAGAGAG TTTTCTCAGA CAACAAAGAT TCAAAGAAAC AGAATTTGAA AAATAATTCC
AAGGTCTTCA ATGATAAGCT CCCAAATAAT GAAGATAGAG TCAGAGGAAG TTTTGCTTTT
GATTCACCTC ATCATTACAC GCCTATTGAA GGAACTCCTT ACTGTTTTTC ACGAAATGAT
TCTTTGAGTT CTCTAGATTT TGATGATGAT GATGTTGACC TTTCCAGGGA AAAGGCTGAA
TTAAGAAAGG CAAAAGAAAA TAAGGAATCA GAGGCTAAAG TTACCAGCCA CACAGAACTA
ACCTCCAACC AACAATCAGC TAATAAGACA CAAGCTATTG CAAAGCAGCC AATAAATCGA
GGTCAGCCTA AACCCATACT TCAGAAACAA TCCACTTTTC CCCAGTCATC CAAAGACATA
CCAGACAGAG GGGCAGCAAC TGATGAAAAG TTACAGAATT TTGCTATTGA AAATACTCCG
GTTTGCTTTT CTCATAATTC CTCTCTGAGT TCTCTCAGTG ACATTGACCA AGAAAACAAC
AATAAAGAAA ATGAACCTAT CAAAGAGACT GAGCCCCCTG ACTCACAGGG AGAACCAAGT
AAACCTCAAG CATCAGGCTA TGCTCCTAAA TCATTTCATG TTGAAGATAC CCCAGTTTGT
TTCTCAAGAA ACAGTTCTCT CAGTTCTCTT AGTATTGACT CTGAAGATGA CCTGTTGCAG
GAATGTATAA GCTCCGCAAT GCCAAAAAAG AAAAAGCCTT CAAGACTCAA GGGTGATAAT
GAAAAACATA GTCCCAGAAA TATGGGTGGC ATATTAGGTG AAGATCTGAC ACTTGATTTG
AAAGATATAC AGAGACCAGA TTCAGAACAT GGTCTATCCC CTGATTCAGA AAATTTTGAT
TGGAAAGCTA TTCAGGAAGG TGCAAATTCC ATAGTAAGTA GTTTACATCA AGCTGCTGCT
GCTGCATGTT TATCTAGACA AGCTTCGTCT GATTCAGATT CCATCCTTTC CCTGAAATCA
GGAATCTCTC TGGGATCACC ATTTCATCTT ACACCTGATC AAGAAGAAAA ACCCTTTACA
AGTAATAAAG GCCCACGAAT TCTAAAACCA GGGGAGAAAA GTACATTGGA AACTAAAAAG
ATAGAATCTG AAAGTAAAGG AATCAAAGGA GGAAAAAAAG TTTATAAAAG TTTGATTACT
GGAAAAGTTC GATCTAATTC AGAAATTTCA GGCCAAATGA AACAGCCCCT TCAAGCAAAC
ATGCCTTCAA TCTCTCGAGG CAGGACAATG ATTCATATTC CAGGAGTTCG AAATAGCTCC
TCAAGTACAA GTCCTGTTTC TAAAAAAGGC CCACCCCTTA AGACTCCAGC CTCCAAAAGC
CCTAGTGAAG GTCAAACAGC CACCACTTCT CCTAGAGGAG CCAAGCCATC TGTGAAATCA
GAATTAAGCC CTGTTGCCAG GCAGACATCC CAAATAGGTG GGTCAAGTAA AGCACCTTCT
AGATCAGGAT CTAGAGATTC GACCCCTTCA AGACCTGCCC AGCAACCATT AAGTAGACCT
ATACAGTCTC CTGGCCGAAA CTCAATTTCC CCTGGTAGAA ATGGAATAAG TCCTCCTAAC
AAATTATCTC AACTTCCAAG GACATCATCC CCTAGTACTG CTTCAACTAA GTCCTCAGGT
TCTGGAAAAA TGTCATATAC ATCTCCAGGT AGACAGATGA GCCAACAGAA CCTTACCAAA
CAAACAGGTT TATCCAAGAA TGCCAGTAGT ATTCCAAGAA GTGAGTCTGC CTCCAAAGGA
CTAAATCAGA TGAATAATGG TAATGGAGCC AATAAAAAGG TAGAACTTTC TAGAATGTCT
TCAACTAAAT CAAGTGGAAG TGAATCTGAT AGATCAGAAA GACCTGTATT AGTACGCCAG
TCAACTTTCA TCAAAGAAGC TCCAAGCCCA ACCTTAAGAA GAAAATTGGA GGAATCTGCT
TCATTTGAAT CTCTTTCTCC ATCATCTAGA CCAGCTTCTC CCACTAGGTC CCAGGCACAA
ACTCCAGTTT TAAGTCCTTC CCTTCCTGAT ATGTCTCTAT CCACACATTC GTCTGTTCAG
GCTGGTGGAT GGCGAAAACT CCCACCTAAT CTCAGTCCCA CTATAGAGTA TAATGATGGA
AGACCAGCAA AGCGCCATGA TATTGCACGG TCTCATTCTG AAAGTCCTTC TAGACTTCCA
ATCAATAGGT CAGGAACCTG GAAACGTGAG CACAGCAAAC ATTCATCATC CCTTCCTCGA
GTAAGCACTT GGAGAAGAAC TGGAAGTTCA TCTTCAATTC TTTCTGCTTC ATCAGAATCC
AGTGAAAAAG CAAAAAGTGA GGATGAAAAA CATGTGAACT CTATTTCAGG AACCAAACAA
AGTAAAGAAA ACCAAGTATC CGCAAAAGGA ACATGGAGAA AAATAAAAGA AAATGAATTT
TCTCCCACAA ATAGTACTTC TCAGACCGTT TCCTCAGGTG CTACAAATGG TGCTGAATCA
AAGACTCTAA TTTATCAAAT GGCACCTGCT GTTTCTAAAA CAGAGGATGT TTGGGTGAGA
ATTGAGGACT GTCCCATTAA CAATCCTAGA TCTGGAAGAT CTCCCACAGG TAATACTCCC
CCGGTGATTG ACAGTGTTTC AGAAAAGGCA AATCCAAACA TTAAAGATTC AAAAGATAAT
CAGGCAAAAC AAAATGTGGG TAATGGCAGT GTTCCCATGC GTACCGTGGG TTTGGAAAAT
CGCCTGAACT CCTTTATTCA GGTGGATGCC CCTGACCAAA AAGGAACTGA GATAAAACCA
GGACAAAATA ATCCTGTCCC TGTATCAGAG ACTAATGAAA GTTCTATAGT GGAACGTACC
CCATTCAGTT CTAGCAGCTC AAGCAAACAC AGTTCACCTA GTGGGACTGT TGCTGCCAGA
GTGACTCCTT TTAATTACAA CCCAAGCCCT AGGAAAAGCA GCGCAGATAG CACTTCAGCT
CGGCCATCTC AGATCCCAAC TCCAGTGAAT AACAACACAA AGAAGCGAGA TTCCAAAACT
GACAGCACAG AATCCAGTGG AACCCAAAGT CCTAAGCGCC ATTCTGGGTC TTACCTTGTG
ACATCTGTTT AA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu16843
Clone ID Related Accession (Same CDS sequence) NM_001127511
Accession Version NM_001127511.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 8478bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 21-MAY-2015
Organism Homo sapiens (human)
Product adenomatous polyposis coli protein isoform a
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP230350.1, AK294544.1, AB210001.1 and CA313732.1. On Sep 14, 2010 this sequence version replaced gi:189011567. Transcript Variant: This variant (1) encodes the shorter isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK294544.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2151741, SAMEA2157437 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
3481
3541
3601
3661
3721
3781
3841
3901
3961
4021
4081
4141
4201
4261
4321
4381
4441
4501
4561
4621
4681
4741
4801
4861
4921
4981
5041
5101
5161
5221
5281
5341
5401
5461
5521
5581
5641
5701
5761
5821
5881
5941
6001
6061
6121
6181
6241
6301
6361
6421
6481
6541
6601
6661
6721
6781
6841
6901
6961
7021
7081
7141
7201
7261
7321
7381
7441
7501
7561
7621
7681
7741
7801
7861
7921
7981
8041
8101
8161
8221
8281
8341
8401
8461
ATGTACGCCT CCCTGGGCTC GGGTCCGGTC GCCCCTTTGC CCGCTTCTGT ACCACCCTCA 
GTTCTCGGGT CCTGGAGCAC CGGCGGCAGC AGGAGCTGCG TCCGGCAGGA GACGAAGAGC
CCGGGCGGCG CTCGTACTTC TGGCCACTGG GCGAGCGTCT GGCAGGAAGT ACTTAAACAA
CTACAAGGAA GTATTGAAGA TGAAGCTATG GCTTCTTCTG GACAGATTGA TTTATTAGAG
CGTCTTAAAG AGCTTAACTT AGATAGCAGT AATTTCCCTG GAGTAAAACT GCGGTCAAAA
ATGTCCCTCC GTTCTTATGG AAGCCGGGAA GGATCTGTAT CAAGCCGTTC TGGAGAGTGC
AGTCCTGTTC CTATGGGTTC ATTTCCAAGA AGAGGGTTTG TAAATGGAAG CAGAGAAAGT
ACTGGATATT TAGAAGAACT TGAGAAAGAG AGGTCATTGC TTCTTGCTGA TCTTGACAAA
GAAGAAAAGG AAAAAGACTG GTATTACGCT CAACTTCAGA ATCTCACTAA AAGAATAGAT
AGTCTTCCTT TAACTGAAAA TTTTTCCTTA CAAACAGATA TGACCAGAAG GCAATTGGAA
TATGAAGCAA GGCAAATCAG AGTTGCGATG GAAGAACAAC TAGGTACCTG CCAGGATATG
GAAAAACGAG CACAGAGGTC ATCTCAGAAC AAGCATGAAA CCGGCTCACA TGATGCTGAG
CGGCAGAATG AAGGTCAAGG AGTGGGAGAA ATCAACATGG CAACTTCTGG TAATGGTCAG
GGTTCAACTA CACGAATGGA CCATGAAACA GCCAGTGTTT TGAGTTCTAG TAGCACACAC
TCTGCACCTC GAAGGCTGAC AAGTCATCTG GGAACCAAGG TGGAAATGGT GTATTCATTG
TTGTCAATGC TTGGTACTCA TGATAAGGAT GATATGTCGC GAACTTTGCT AGCTATGTCT
AGCTCCCAAG ACAGCTGTAT ATCCATGCGA CAGTCTGGAT GTCTTCCTCT CCTCATCCAG
CTTTTACATG GCAATGACAA AGACTCTGTA TTGTTGGGAA ATTCCCGGGG CAGTAAAGAG
GCTCGGGCCA GGGCCAGTGC AGCACTCCAC AACATCATTC ACTCACAGCC TGATGACAAG
AGAGGCAGGC GTGAAATCCG AGTCCTTCAT CTTTTGGAAC AGATACGCGC TTACTGTGAA
ACCTGTTGGG AGTGGCAGGA AGCTCATGAA CCAGGCATGG ACCAGGACAA AAATCCAATG
CCAGCTCCTG TTGAACATCA GATCTGTCCT GCTGTGTGTG TTCTAATGAA ACTTTCATTT
GATGAAGAGC ATAGACATGC AATGAATGAA CTAGGGGGAC TACAGGCCAT TGCAGAATTA
TTGCAAGTGG ACTGTGAAAT GTATGGGCTT ACTAATGACC ACTACAGTAT TACACTAAGA
CGATATGCTG GAATGGCTTT GACAAACTTG ACTTTTGGAG ATGTAGCCAA CAAGGCTACG
CTATGCTCTA TGAAAGGCTG CATGAGAGCA CTTGTGGCCC AACTAAAATC TGAAAGTGAA
GACTTACAGC AGGTTATTGC GAGTGTTTTG AGGAATTTGT CTTGGCGAGC AGATGTAAAT
AGTAAAAAGA CGTTGCGAGA AGTTGGAAGT GTGAAAGCAT TGATGGAATG TGCTTTAGAA
GTTAAAAAGG AATCAACCCT CAAAAGCGTA TTGAGTGCCT TATGGAATTT GTCAGCACAT
TGCACTGAGA ATAAAGCTGA TATATGTGCT GTAGATGGTG CACTTGCATT TTTGGTTGGC
ACTCTTACTT ACCGGAGCCA GACAAACACT TTAGCCATTA TTGAAAGTGG AGGTGGGATA
TTACGGAATG TGTCCAGCTT GATAGCTACA AATGAGGACC ACAGGCAAAT CCTAAGAGAG
AACAACTGTC TACAAACTTT ATTACAACAC TTAAAATCTC ATAGTTTGAC AATAGTCAGT
AATGCATGTG GAACTTTGTG GAATCTCTCA GCAAGAAATC CTAAAGACCA GGAAGCATTA
TGGGACATGG GGGCAGTTAG CATGCTCAAG AACCTCATTC ATTCAAAGCA CAAAATGATT
GCTATGGGAA GTGCTGCAGC TTTAAGGAAT CTCATGGCAA ATAGGCCTGC GAAGTACAAG
GATGCCAATA TTATGTCTCC TGGCTCAAGC TTGCCATCTC TTCATGTTAG GAAACAAAAA
GCCCTAGAAG CAGAATTAGA TGCTCAGCAC TTATCAGAAA CTTTTGACAA TATAGACAAT
TTAAGTCCCA AGGCATCTCA TCGTAGTAAG CAGAGACACA AGCAAAGTCT CTATGGTGAT
TATGTTTTTG ACACCAATCG ACATGATGAT AATAGGTCAG ACAATTTTAA TACTGGCAAC
ATGACTGTCC TTTCACCATA TTTGAATACT ACAGTGTTAC CCAGCTCCTC TTCATCAAGA
GGAAGCTTAG ATAGTTCTCG TTCTGAAAAA GATAGAAGTT TGGAGAGAGA ACGCGGAATT
GGTCTAGGCA ACTACCATCC AGCAACAGAA AATCCAGGAA CTTCTTCAAA GCGAGGTTTG
CAGATCTCCA CCACTGCAGC CCAGATTGCC AAAGTCATGG AAGAAGTGTC AGCCATTCAT
ACCTCTCAGG AAGACAGAAG TTCTGGGTCT ACCACTGAAT TACATTGTGT GACAGATGAG
AGAAATGCAC TTAGAAGAAG CTCTGCTGCC CATACACATT CAAACACTTA CAATTTCACT
AAGTCGGAAA ATTCAAATAG GACATGTTCT ATGCCTTATG CCAAATTAGA ATACAAGAGA
TCTTCAAATG ATAGTTTAAA TAGTGTCAGT AGTAGTGATG GTTATGGTAA AAGAGGTCAA
ATGAAACCCT CGATTGAATC CTATTCTGAA GATGATGAAA GTAAGTTTTG CAGTTATGGT
CAATACCCAG CCGACCTAGC CCATAAAATA CATAGTGCAA ATCATATGGA TGATAATGAT
GGAGAACTAG ATACACCAAT AAATTATAGT CTTAAATATT CAGATGAGCA GTTGAACTCT
GGAAGGCAAA GTCCTTCACA GAATGAAAGA TGGGCAAGAC CCAAACACAT AATAGAAGAT
GAAATAAAAC AAAGTGAGCA AAGACAATCA AGGAATCAAA GTACAACTTA TCCTGTTTAT
ACTGAGAGCA CTGATGATAA ACACCTCAAG TTCCAACCAC ATTTTGGACA GCAGGAATGT
GTTTCTCCAT ACAGGTCACG GGGAGCCAAT GGTTCAGAAA CAAATCGAGT GGGTTCTAAT
CATGGAATTA ATCAAAATGT AAGCCAGTCT TTGTGTCAAG AAGATGACTA TGAAGATGAT
AAGCCTACCA ATTATAGTGA ACGTTACTCT GAAGAAGAAC AGCATGAAGA AGAAGAGAGA
CCAACAAATT ATAGCATAAA ATATAATGAA GAGAAACGTC ATGTGGATCA GCCTATTGAT
TATAGTTTAA AATATGCCAC AGATATTCCT TCATCACAGA AACAGTCATT TTCATTCTCA
AAGAGTTCAT CTGGACAAAG CAGTAAAACC GAACATATGT CTTCAAGCAG TGAGAATACG
TCCACACCTT CATCTAATGC CAAGAGGCAG AATCAGCTCC ATCCAAGTTC TGCACAGAGT
AGAAGTGGTC AGCCTCAAAA GGCTGCCACT TGCAAAGTTT CTTCTATTAA CCAAGAAACA
ATACAGACTT ATTGTGTAGA AGATACTCCA ATATGTTTTT CAAGATGTAG TTCATTATCA
TCTTTGTCAT CAGCTGAAGA TGAAATAGGA TGTAATCAGA CGACACAGGA AGCAGATTCT
GCTAATACCC TGCAAATAGC AGAAATAAAA GAAAAGATTG GAACTAGGTC AGCTGAAGAT
CCTGTGAGCG AAGTTCCAGC AGTGTCACAG CACCCTAGAA CCAAATCCAG CAGACTGCAG
GGTTCTAGTT TATCTTCAGA ATCAGCCAGG CACAAAGCTG TTGAATTTTC TTCAGGAGCG
AAATCTCCCT CCAAAAGTGG TGCTCAGACA CCCAAAAGTC CACCTGAACA CTATGTTCAG
GAGACCCCAC TCATGTTTAG CAGATGTACT TCTGTCAGTT CACTTGATAG TTTTGAGAGT
CGTTCGATTG CCAGCTCCGT TCAGAGTGAA CCATGCAGTG GAATGGTAAG TGGCATTATA
AGCCCCAGTG ATCTTCCAGA TAGCCCTGGA CAAACCATGC CACCAAGCAG AAGTAAAACA
CCTCCACCAC CTCCTCAAAC AGCTCAAACC AAGCGAGAAG TACCTAAAAA TAAAGCACCT
ACTGCTGAAA AGAGAGAGAG TGGACCTAAG CAAGCTGCAG TAAATGCTGC AGTTCAGAGG
GTCCAGGTTC TTCCAGATGC TGATACTTTA TTACATTTTG CCACGGAAAG TACTCCAGAT
GGATTTTCTT GTTCATCCAG CCTGAGTGCT CTGAGCCTCG ATGAGCCATT TATACAGAAA
GATGTGGAAT TAAGAATAAT GCCTCCAGTT CAGGAAAATG ACAATGGGAA TGAAACAGAA
TCAGAGCAGC CTAAAGAATC AAATGAAAAC CAAGAGAAAG AGGCAGAAAA AACTATTGAT
TCTGAAAAGG ACCTATTAGA TGATTCAGAT GATGATGATA TTGAAATACT AGAAGAATGT
ATTATTTCTG CCATGCCAAC AAAGTCATCA CGTAAAGCAA AAAAGCCAGC CCAGACTGCT
TCAAAATTAC CTCCACCTGT GGCAAGGAAA CCAAGTCAGC TGCCTGTGTA CAAACTTCTA
CCATCACAAA ACAGGTTGCA ACCCCAAAAG CATGTTAGTT TTACACCGGG GGATGATATG
CCACGGGTGT ATTGTGTTGA AGGGACACCT ATAAACTTTT CCACAGCTAC ATCTCTAAGT
GATCTAACAA TCGAATCCCC TCCAAATGAG TTAGCTGCTG GAGAAGGAGT TAGAGGAGGG
GCACAGTCAG GTGAATTTGA AAAACGAGAT ACCATTCCTA CAGAAGGCAG AAGTACAGAT
GAGGCTCAAG GAGGAAAAAC CTCATCTGTA ACCATACCTG AATTGGATGA CAATAAAGCA
GAGGAAGGTG ATATTCTTGC AGAATGCATT AATTCTGCTA TGCCCAAAGG GAAAAGTCAC
AAGCCTTTCC GTGTGAAAAA GATAATGGAC CAGGTCCAGC AAGCATCTGC GTCTTCTTCT
GCACCCAACA AAAATCAGTT AGATGGTAAG AAAAAGAAAC CAACTTCACC AGTAAAACCT
ATACCACAAA ATACTGAATA TAGGACACGT GTAAGAAAAA ATGCAGACTC AAAAAATAAT
TTAAATGCTG AGAGAGTTTT CTCAGACAAC AAAGATTCAA AGAAACAGAA TTTGAAAAAT
AATTCCAAGG TCTTCAATGA TAAGCTCCCA AATAATGAAG ATAGAGTCAG AGGAAGTTTT
GCTTTTGATT CACCTCATCA TTACACGCCT ATTGAAGGAA CTCCTTACTG TTTTTCACGA
AATGATTCTT TGAGTTCTCT AGATTTTGAT GATGATGATG TTGACCTTTC CAGGGAAAAG
GCTGAATTAA GAAAGGCAAA AGAAAATAAG GAATCAGAGG CTAAAGTTAC CAGCCACACA
GAACTAACCT CCAACCAACA ATCAGCTAAT AAGACACAAG CTATTGCAAA GCAGCCAATA
AATCGAGGTC AGCCTAAACC CATACTTCAG AAACAATCCA CTTTTCCCCA GTCATCCAAA
GACATACCAG ACAGAGGGGC AGCAACTGAT GAAAAGTTAC AGAATTTTGC TATTGAAAAT
ACTCCGGTTT GCTTTTCTCA TAATTCCTCT CTGAGTTCTC TCAGTGACAT TGACCAAGAA
AACAACAATA AAGAAAATGA ACCTATCAAA GAGACTGAGC CCCCTGACTC ACAGGGAGAA
CCAAGTAAAC CTCAAGCATC AGGCTATGCT CCTAAATCAT TTCATGTTGA AGATACCCCA
GTTTGTTTCT CAAGAAACAG TTCTCTCAGT TCTCTTAGTA TTGACTCTGA AGATGACCTG
TTGCAGGAAT GTATAAGCTC CGCAATGCCA AAAAAGAAAA AGCCTTCAAG ACTCAAGGGT
GATAATGAAA AACATAGTCC CAGAAATATG GGTGGCATAT TAGGTGAAGA TCTGACACTT
GATTTGAAAG ATATACAGAG ACCAGATTCA GAACATGGTC TATCCCCTGA TTCAGAAAAT
TTTGATTGGA AAGCTATTCA GGAAGGTGCA AATTCCATAG TAAGTAGTTT ACATCAAGCT
GCTGCTGCTG CATGTTTATC TAGACAAGCT TCGTCTGATT CAGATTCCAT CCTTTCCCTG
AAATCAGGAA TCTCTCTGGG ATCACCATTT CATCTTACAC CTGATCAAGA AGAAAAACCC
TTTACAAGTA ATAAAGGCCC ACGAATTCTA AAACCAGGGG AGAAAAGTAC ATTGGAAACT
AAAAAGATAG AATCTGAAAG TAAAGGAATC AAAGGAGGAA AAAAAGTTTA TAAAAGTTTG
ATTACTGGAA AAGTTCGATC TAATTCAGAA ATTTCAGGCC AAATGAAACA GCCCCTTCAA
GCAAACATGC CTTCAATCTC TCGAGGCAGG ACAATGATTC ATATTCCAGG AGTTCGAAAT
AGCTCCTCAA GTACAAGTCC TGTTTCTAAA AAAGGCCCAC CCCTTAAGAC TCCAGCCTCC
AAAAGCCCTA GTGAAGGTCA AACAGCCACC ACTTCTCCTA GAGGAGCCAA GCCATCTGTG
AAATCAGAAT TAAGCCCTGT TGCCAGGCAG ACATCCCAAA TAGGTGGGTC AAGTAAAGCA
CCTTCTAGAT CAGGATCTAG AGATTCGACC CCTTCAAGAC CTGCCCAGCA ACCATTAAGT
AGACCTATAC AGTCTCCTGG CCGAAACTCA ATTTCCCCTG GTAGAAATGG AATAAGTCCT
CCTAACAAAT TATCTCAACT TCCAAGGACA TCATCCCCTA GTACTGCTTC AACTAAGTCC
TCAGGTTCTG GAAAAATGTC ATATACATCT CCAGGTAGAC AGATGAGCCA ACAGAACCTT
ACCAAACAAA CAGGTTTATC CAAGAATGCC AGTAGTATTC CAAGAAGTGA GTCTGCCTCC
AAAGGACTAA ATCAGATGAA TAATGGTAAT GGAGCCAATA AAAAGGTAGA ACTTTCTAGA
ATGTCTTCAA CTAAATCAAG TGGAAGTGAA TCTGATAGAT CAGAAAGACC TGTATTAGTA
CGCCAGTCAA CTTTCATCAA AGAAGCTCCA AGCCCAACCT TAAGAAGAAA ATTGGAGGAA
TCTGCTTCAT TTGAATCTCT TTCTCCATCA TCTAGACCAG CTTCTCCCAC TAGGTCCCAG
GCACAAACTC CAGTTTTAAG TCCTTCCCTT CCTGATATGT CTCTATCCAC ACATTCGTCT
GTTCAGGCTG GTGGATGGCG AAAACTCCCA CCTAATCTCA GTCCCACTAT AGAGTATAAT
GATGGAAGAC CAGCAAAGCG CCATGATATT GCACGGTCTC ATTCTGAAAG TCCTTCTAGA
CTTCCAATCA ATAGGTCAGG AACCTGGAAA CGTGAGCACA GCAAACATTC ATCATCCCTT
CCTCGAGTAA GCACTTGGAG AAGAACTGGA AGTTCATCTT CAATTCTTTC TGCTTCATCA
GAATCCAGTG AAAAAGCAAA AAGTGAGGAT GAAAAACATG TGAACTCTAT TTCAGGAACC
AAACAAAGTA AAGAAAACCA AGTATCCGCA AAAGGAACAT GGAGAAAAAT AAAAGAAAAT
GAATTTTCTC CCACAAATAG TACTTCTCAG ACCGTTTCCT CAGGTGCTAC AAATGGTGCT
GAATCAAAGA CTCTAATTTA TCAAATGGCA CCTGCTGTTT CTAAAACAGA GGATGTTTGG
GTGAGAATTG AGGACTGTCC CATTAACAAT CCTAGATCTG GAAGATCTCC CACAGGTAAT
ACTCCCCCGG TGATTGACAG TGTTTCAGAA AAGGCAAATC CAAACATTAA AGATTCAAAA
GATAATCAGG CAAAACAAAA TGTGGGTAAT GGCAGTGTTC CCATGCGTAC CGTGGGTTTG
GAAAATCGCC TGAACTCCTT TATTCAGGTG GATGCCCCTG ACCAAAAAGG AACTGAGATA
AAACCAGGAC AAAATAATCC TGTCCCTGTA TCAGAGACTA ATGAAAGTTC TATAGTGGAA
CGTACCCCAT TCAGTTCTAG CAGCTCAAGC AAACACAGTT CACCTAGTGG GACTGTTGCT
GCCAGAGTGA CTCCTTTTAA TTACAACCCA AGCCCTAGGA AAAGCAGCGC AGATAGCACT
TCAGCTCGGC CATCTCAGAT CCCAACTCCA GTGAATAACA ACACAAAGAA GCGAGATTCC
AAAACTGACA GCACAGAATC CAGTGGAACC CAAAGTCCTA AGCGCCATTC TGGGTCTTAC
CTTGTGACAT CTGTTTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001120983.2
CDS214..8691
Misc Feature(1)175..177(+)
Misc Feature(2)619..867(+)
Misc Feature(3)1090..1398(+)
Misc Feature(4)1150..1326(+)
Misc Feature(5)1549..1950(+)
Misc Feature(6)1654..1950(+)
Misc Feature(7)1990..2352(+)
Misc Feature(8)2056..2352(+)
Misc Feature(9)4264..4341(+)
Misc Feature(10)5065..5142(+)
Misc Feature(11)5314..5373(+)
Misc Feature(12)6259..6318(+)
Misc Feature(13)6826..7863(+)
Misc Feature(14)8167..8688(+)
Exon (1)1..378
Gene:APC
Gene Synonym:
Exon (2)379..463
Gene:APC
Gene Synonym:
Exon (3)464..665
Gene:APC
Gene Synonym:
Exon (4)666..774
Gene:APC
Gene Synonym:
Exon (5)775..888
Gene:APC
Gene Synonym:
Exon (6)889..993
Gene:APC
Gene Synonym:
Exon (7)994..1092
Gene:APC
Gene Synonym:
Exon (8)1093..1471
Gene:APC
Gene Synonym:
Exon (9)1472..1567
Gene:APC
Gene Synonym:
Exon (10)1568..1707
Gene:APC
Gene Synonym:
Exon (11)1708..1785
Gene:APC
Gene Synonym:
Exon (12)1786..1902
Gene:APC
Gene Synonym:
Exon (13)1903..2117
Gene:APC
Gene Synonym:
Exon (14)2118..10804
Gene:APC
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001127511
Organism Homo sapiens (human)
Definition Homo sapiens adenomatous polyposis coli (APC), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001127511

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
3481
3541
3601
3661
3721
3781
3841
3901
3961
4021
4081
4141
4201
4261
4321
4381
4441
4501
4561
4621
4681
4741
4801
4861
4921
4981
5041
5101
5161
5221
5281
5341
5401
5461
5521
5581
5641
5701
5761
5821
5881
5941
6001
6061
6121
6181
6241
6301
6361
6421
6481
6541
6601
6661
6721
6781
6841
6901
6961
7021
7081
7141
7201
7261
7321
7381
7441
7501
7561
7621
7681
7741
7801
7861
7921
7981
8041
8101
8161
8221
8281
8341
8401
8461
ATGTACGCCT CCCTGGGCTC GGGTCCGGTC GCCCCTTTGC CCGCTTCTGT ACCACCCTCA 
GTTCTCGGGT CCTGGAGCAC CGGCGGCAGC AGGAGCTGCG TCCGGCAGGA GACGAAGAGC
CCGGGCGGCG CTCGTACTTC TGGCCACTGG GCGAGCGTCT GGCAGGAAGT ACTTAAACAA
CTACAAGGAA GTATTGAAGA TGAAGCTATG GCTTCTTCTG GACAGATTGA TTTATTAGAG
CGTCTTAAAG AGCTTAACTT AGATAGCAGT AATTTCCCTG GAGTAAAACT GCGGTCAAAA
ATGTCCCTCC GTTCTTATGG AAGCCGGGAA GGATCTGTAT CAAGCCGTTC TGGAGAGTGC
AGTCCTGTTC CTATGGGTTC ATTTCCAAGA AGAGGGTTTG TAAATGGAAG CAGAGAAAGT
ACTGGATATT TAGAAGAACT TGAGAAAGAG AGGTCATTGC TTCTTGCTGA TCTTGACAAA
GAAGAAAAGG AAAAAGACTG GTATTACGCT CAACTTCAGA ATCTCACTAA AAGAATAGAT
AGTCTTCCTT TAACTGAAAA TTTTTCCTTA CAAACAGATA TGACCAGAAG GCAATTGGAA
TATGAAGCAA GGCAAATCAG AGTTGCGATG GAAGAACAAC TAGGTACCTG CCAGGATATG
GAAAAACGAG CACAGAGGTC ATCTCAGAAC AAGCATGAAA CCGGCTCACA TGATGCTGAG
CGGCAGAATG AAGGTCAAGG AGTGGGAGAA ATCAACATGG CAACTTCTGG TAATGGTCAG
GGTTCAACTA CACGAATGGA CCATGAAACA GCCAGTGTTT TGAGTTCTAG TAGCACACAC
TCTGCACCTC GAAGGCTGAC AAGTCATCTG GGAACCAAGG TGGAAATGGT GTATTCATTG
TTGTCAATGC TTGGTACTCA TGATAAGGAT GATATGTCGC GAACTTTGCT AGCTATGTCT
AGCTCCCAAG ACAGCTGTAT ATCCATGCGA CAGTCTGGAT GTCTTCCTCT CCTCATCCAG
CTTTTACATG GCAATGACAA AGACTCTGTA TTGTTGGGAA ATTCCCGGGG CAGTAAAGAG
GCTCGGGCCA GGGCCAGTGC AGCACTCCAC AACATCATTC ACTCACAGCC TGATGACAAG
AGAGGCAGGC GTGAAATCCG AGTCCTTCAT CTTTTGGAAC AGATACGCGC TTACTGTGAA
ACCTGTTGGG AGTGGCAGGA AGCTCATGAA CCAGGCATGG ACCAGGACAA AAATCCAATG
CCAGCTCCTG TTGAACATCA GATCTGTCCT GCTGTGTGTG TTCTAATGAA ACTTTCATTT
GATGAAGAGC ATAGACATGC AATGAATGAA CTAGGGGGAC TACAGGCCAT TGCAGAATTA
TTGCAAGTGG ACTGTGAAAT GTATGGGCTT ACTAATGACC ACTACAGTAT TACACTAAGA
CGATATGCTG GAATGGCTTT GACAAACTTG ACTTTTGGAG ATGTAGCCAA CAAGGCTACG
CTATGCTCTA TGAAAGGCTG CATGAGAGCA CTTGTGGCCC AACTAAAATC TGAAAGTGAA
GACTTACAGC AGGTTATTGC GAGTGTTTTG AGGAATTTGT CTTGGCGAGC AGATGTAAAT
AGTAAAAAGA CGTTGCGAGA AGTTGGAAGT GTGAAAGCAT TGATGGAATG TGCTTTAGAA
GTTAAAAAGG AATCAACCCT CAAAAGCGTA TTGAGTGCCT TATGGAATTT GTCAGCACAT
TGCACTGAGA ATAAAGCTGA TATATGTGCT GTAGATGGTG CACTTGCATT TTTGGTTGGC
ACTCTTACTT ACCGGAGCCA GACAAACACT TTAGCCATTA TTGAAAGTGG AGGTGGGATA
TTACGGAATG TGTCCAGCTT GATAGCTACA AATGAGGACC ACAGGCAAAT CCTAAGAGAG
AACAACTGTC TACAAACTTT ATTACAACAC TTAAAATCTC ATAGTTTGAC AATAGTCAGT
AATGCATGTG GAACTTTGTG GAATCTCTCA GCAAGAAATC CTAAAGACCA GGAAGCATTA
TGGGACATGG GGGCAGTTAG CATGCTCAAG AACCTCATTC ATTCAAAGCA CAAAATGATT
GCTATGGGAA GTGCTGCAGC TTTAAGGAAT CTCATGGCAA ATAGGCCTGC GAAGTACAAG
GATGCCAATA TTATGTCTCC TGGCTCAAGC TTGCCATCTC TTCATGTTAG GAAACAAAAA
GCCCTAGAAG CAGAATTAGA TGCTCAGCAC TTATCAGAAA CTTTTGACAA TATAGACAAT
TTAAGTCCCA AGGCATCTCA TCGTAGTAAG CAGAGACACA AGCAAAGTCT CTATGGTGAT
TATGTTTTTG ACACCAATCG ACATGATGAT AATAGGTCAG ACAATTTTAA TACTGGCAAC
ATGACTGTCC TTTCACCATA TTTGAATACT ACAGTGTTAC CCAGCTCCTC TTCATCAAGA
GGAAGCTTAG ATAGTTCTCG TTCTGAAAAA GATAGAAGTT TGGAGAGAGA ACGCGGAATT
GGTCTAGGCA ACTACCATCC AGCAACAGAA AATCCAGGAA CTTCTTCAAA GCGAGGTTTG
CAGATCTCCA CCACTGCAGC CCAGATTGCC AAAGTCATGG AAGAAGTGTC AGCCATTCAT
ACCTCTCAGG AAGACAGAAG TTCTGGGTCT ACCACTGAAT TACATTGTGT GACAGATGAG
AGAAATGCAC TTAGAAGAAG CTCTGCTGCC CATACACATT CAAACACTTA CAATTTCACT
AAGTCGGAAA ATTCAAATAG GACATGTTCT ATGCCTTATG CCAAATTAGA ATACAAGAGA
TCTTCAAATG ATAGTTTAAA TAGTGTCAGT AGTAGTGATG GTTATGGTAA AAGAGGTCAA
ATGAAACCCT CGATTGAATC CTATTCTGAA GATGATGAAA GTAAGTTTTG CAGTTATGGT
CAATACCCAG CCGACCTAGC CCATAAAATA CATAGTGCAA ATCATATGGA TGATAATGAT
GGAGAACTAG ATACACCAAT AAATTATAGT CTTAAATATT CAGATGAGCA GTTGAACTCT
GGAAGGCAAA GTCCTTCACA GAATGAAAGA TGGGCAAGAC CCAAACACAT AATAGAAGAT
GAAATAAAAC AAAGTGAGCA AAGACAATCA AGGAATCAAA GTACAACTTA TCCTGTTTAT
ACTGAGAGCA CTGATGATAA ACACCTCAAG TTCCAACCAC ATTTTGGACA GCAGGAATGT
GTTTCTCCAT ACAGGTCACG GGGAGCCAAT GGTTCAGAAA CAAATCGAGT GGGTTCTAAT
CATGGAATTA ATCAAAATGT AAGCCAGTCT TTGTGTCAAG AAGATGACTA TGAAGATGAT
AAGCCTACCA ATTATAGTGA ACGTTACTCT GAAGAAGAAC AGCATGAAGA AGAAGAGAGA
CCAACAAATT ATAGCATAAA ATATAATGAA GAGAAACGTC ATGTGGATCA GCCTATTGAT
TATAGTTTAA AATATGCCAC AGATATTCCT TCATCACAGA AACAGTCATT TTCATTCTCA
AAGAGTTCAT CTGGACAAAG CAGTAAAACC GAACATATGT CTTCAAGCAG TGAGAATACG
TCCACACCTT CATCTAATGC CAAGAGGCAG AATCAGCTCC ATCCAAGTTC TGCACAGAGT
AGAAGTGGTC AGCCTCAAAA GGCTGCCACT TGCAAAGTTT CTTCTATTAA CCAAGAAACA
ATACAGACTT ATTGTGTAGA AGATACTCCA ATATGTTTTT CAAGATGTAG TTCATTATCA
TCTTTGTCAT CAGCTGAAGA TGAAATAGGA TGTAATCAGA CGACACAGGA AGCAGATTCT
GCTAATACCC TGCAAATAGC AGAAATAAAA GAAAAGATTG GAACTAGGTC AGCTGAAGAT
CCTGTGAGCG AAGTTCCAGC AGTGTCACAG CACCCTAGAA CCAAATCCAG CAGACTGCAG
GGTTCTAGTT TATCTTCAGA ATCAGCCAGG CACAAAGCTG TTGAATTTTC TTCAGGAGCG
AAATCTCCCT CCAAAAGTGG TGCTCAGACA CCCAAAAGTC CACCTGAACA CTATGTTCAG
GAGACCCCAC TCATGTTTAG CAGATGTACT TCTGTCAGTT CACTTGATAG TTTTGAGAGT
CGTTCGATTG CCAGCTCCGT TCAGAGTGAA CCATGCAGTG GAATGGTAAG TGGCATTATA
AGCCCCAGTG ATCTTCCAGA TAGCCCTGGA CAAACCATGC CACCAAGCAG AAGTAAAACA
CCTCCACCAC CTCCTCAAAC AGCTCAAACC AAGCGAGAAG TACCTAAAAA TAAAGCACCT
ACTGCTGAAA AGAGAGAGAG TGGACCTAAG CAAGCTGCAG TAAATGCTGC AGTTCAGAGG
GTCCAGGTTC TTCCAGATGC TGATACTTTA TTACATTTTG CCACGGAAAG TACTCCAGAT
GGATTTTCTT GTTCATCCAG CCTGAGTGCT CTGAGCCTCG ATGAGCCATT TATACAGAAA
GATGTGGAAT TAAGAATAAT GCCTCCAGTT CAGGAAAATG ACAATGGGAA TGAAACAGAA
TCAGAGCAGC CTAAAGAATC AAATGAAAAC CAAGAGAAAG AGGCAGAAAA AACTATTGAT
TCTGAAAAGG ACCTATTAGA TGATTCAGAT GATGATGATA TTGAAATACT AGAAGAATGT
ATTATTTCTG CCATGCCAAC AAAGTCATCA CGTAAAGCAA AAAAGCCAGC CCAGACTGCT
TCAAAATTAC CTCCACCTGT GGCAAGGAAA CCAAGTCAGC TGCCTGTGTA CAAACTTCTA
CCATCACAAA ACAGGTTGCA ACCCCAAAAG CATGTTAGTT TTACACCGGG GGATGATATG
CCACGGGTGT ATTGTGTTGA AGGGACACCT ATAAACTTTT CCACAGCTAC ATCTCTAAGT
GATCTAACAA TCGAATCCCC TCCAAATGAG TTAGCTGCTG GAGAAGGAGT TAGAGGAGGG
GCACAGTCAG GTGAATTTGA AAAACGAGAT ACCATTCCTA CAGAAGGCAG AAGTACAGAT
GAGGCTCAAG GAGGAAAAAC CTCATCTGTA ACCATACCTG AATTGGATGA CAATAAAGCA
GAGGAAGGTG ATATTCTTGC AGAATGCATT AATTCTGCTA TGCCCAAAGG GAAAAGTCAC
AAGCCTTTCC GTGTGAAAAA GATAATGGAC CAGGTCCAGC AAGCATCTGC GTCTTCTTCT
GCACCCAACA AAAATCAGTT AGATGGTAAG AAAAAGAAAC CAACTTCACC AGTAAAACCT
ATACCACAAA ATACTGAATA TAGGACACGT GTAAGAAAAA ATGCAGACTC AAAAAATAAT
TTAAATGCTG AGAGAGTTTT CTCAGACAAC AAAGATTCAA AGAAACAGAA TTTGAAAAAT
AATTCCAAGG TCTTCAATGA TAAGCTCCCA AATAATGAAG ATAGAGTCAG AGGAAGTTTT
GCTTTTGATT CACCTCATCA TTACACGCCT ATTGAAGGAA CTCCTTACTG TTTTTCACGA
AATGATTCTT TGAGTTCTCT AGATTTTGAT GATGATGATG TTGACCTTTC CAGGGAAAAG
GCTGAATTAA GAAAGGCAAA AGAAAATAAG GAATCAGAGG CTAAAGTTAC CAGCCACACA
GAACTAACCT CCAACCAACA ATCAGCTAAT AAGACACAAG CTATTGCAAA GCAGCCAATA
AATCGAGGTC AGCCTAAACC CATACTTCAG AAACAATCCA CTTTTCCCCA GTCATCCAAA
GACATACCAG ACAGAGGGGC AGCAACTGAT GAAAAGTTAC AGAATTTTGC TATTGAAAAT
ACTCCGGTTT GCTTTTCTCA TAATTCCTCT CTGAGTTCTC TCAGTGACAT TGACCAAGAA
AACAACAATA AAGAAAATGA ACCTATCAAA GAGACTGAGC CCCCTGACTC ACAGGGAGAA
CCAAGTAAAC CTCAAGCATC AGGCTATGCT CCTAAATCAT TTCATGTTGA AGATACCCCA
GTTTGTTTCT CAAGAAACAG TTCTCTCAGT TCTCTTAGTA TTGACTCTGA AGATGACCTG
TTGCAGGAAT GTATAAGCTC CGCAATGCCA AAAAAGAAAA AGCCTTCAAG ACTCAAGGGT
GATAATGAAA AACATAGTCC CAGAAATATG GGTGGCATAT TAGGTGAAGA TCTGACACTT
GATTTGAAAG ATATACAGAG ACCAGATTCA GAACATGGTC TATCCCCTGA TTCAGAAAAT
TTTGATTGGA AAGCTATTCA GGAAGGTGCA AATTCCATAG TAAGTAGTTT ACATCAAGCT
GCTGCTGCTG CATGTTTATC TAGACAAGCT TCGTCTGATT CAGATTCCAT CCTTTCCCTG
AAATCAGGAA TCTCTCTGGG ATCACCATTT CATCTTACAC CTGATCAAGA AGAAAAACCC
TTTACAAGTA ATAAAGGCCC ACGAATTCTA AAACCAGGGG AGAAAAGTAC ATTGGAAACT
AAAAAGATAG AATCTGAAAG TAAAGGAATC AAAGGAGGAA AAAAAGTTTA TAAAAGTTTG
ATTACTGGAA AAGTTCGATC TAATTCAGAA ATTTCAGGCC AAATGAAACA GCCCCTTCAA
GCAAACATGC CTTCAATCTC TCGAGGCAGG ACAATGATTC ATATTCCAGG AGTTCGAAAT
AGCTCCTCAA GTACAAGTCC TGTTTCTAAA AAAGGCCCAC CCCTTAAGAC TCCAGCCTCC
AAAAGCCCTA GTGAAGGTCA AACAGCCACC ACTTCTCCTA GAGGAGCCAA GCCATCTGTG
AAATCAGAAT TAAGCCCTGT TGCCAGGCAG ACATCCCAAA TAGGTGGGTC AAGTAAAGCA
CCTTCTAGAT CAGGATCTAG AGATTCGACC CCTTCAAGAC CTGCCCAGCA ACCATTAAGT
AGACCTATAC AGTCTCCTGG CCGAAACTCA ATTTCCCCTG GTAGAAATGG AATAAGTCCT
CCTAACAAAT TATCTCAACT TCCAAGGACA TCATCCCCTA GTACTGCTTC AACTAAGTCC
TCAGGTTCTG GAAAAATGTC ATATACATCT CCAGGTAGAC AGATGAGCCA ACAGAACCTT
ACCAAACAAA CAGGTTTATC CAAGAATGCC AGTAGTATTC CAAGAAGTGA GTCTGCCTCC
AAAGGACTAA ATCAGATGAA TAATGGTAAT GGAGCCAATA AAAAGGTAGA ACTTTCTAGA
ATGTCTTCAA CTAAATCAAG TGGAAGTGAA TCTGATAGAT CAGAAAGACC TGTATTAGTA
CGCCAGTCAA CTTTCATCAA AGAAGCTCCA AGCCCAACCT TAAGAAGAAA ATTGGAGGAA
TCTGCTTCAT TTGAATCTCT TTCTCCATCA TCTAGACCAG CTTCTCCCAC TAGGTCCCAG
GCACAAACTC CAGTTTTAAG TCCTTCCCTT CCTGATATGT CTCTATCCAC ACATTCGTCT
GTTCAGGCTG GTGGATGGCG AAAACTCCCA CCTAATCTCA GTCCCACTAT AGAGTATAAT
GATGGAAGAC CAGCAAAGCG CCATGATATT GCACGGTCTC ATTCTGAAAG TCCTTCTAGA
CTTCCAATCA ATAGGTCAGG AACCTGGAAA CGTGAGCACA GCAAACATTC ATCATCCCTT
CCTCGAGTAA GCACTTGGAG AAGAACTGGA AGTTCATCTT CAATTCTTTC TGCTTCATCA
GAATCCAGTG AAAAAGCAAA AAGTGAGGAT GAAAAACATG TGAACTCTAT TTCAGGAACC
AAACAAAGTA AAGAAAACCA AGTATCCGCA AAAGGAACAT GGAGAAAAAT AAAAGAAAAT
GAATTTTCTC CCACAAATAG TACTTCTCAG ACCGTTTCCT CAGGTGCTAC AAATGGTGCT
GAATCAAAGA CTCTAATTTA TCAAATGGCA CCTGCTGTTT CTAAAACAGA GGATGTTTGG
GTGAGAATTG AGGACTGTCC CATTAACAAT CCTAGATCTG GAAGATCTCC CACAGGTAAT
ACTCCCCCGG TGATTGACAG TGTTTCAGAA AAGGCAAATC CAAACATTAA AGATTCAAAA
GATAATCAGG CAAAACAAAA TGTGGGTAAT GGCAGTGTTC CCATGCGTAC CGTGGGTTTG
GAAAATCGCC TGAACTCCTT TATTCAGGTG GATGCCCCTG ACCAAAAAGG AACTGAGATA
AAACCAGGAC AAAATAATCC TGTCCCTGTA TCAGAGACTA ATGAAAGTTC TATAGTGGAA
CGTACCCCAT TCAGTTCTAG CAGCTCAAGC AAACACAGTT CACCTAGTGG GACTGTTGCT
GCCAGAGTGA CTCCTTTTAA TTACAACCCA AGCCCTAGGA AAAGCAGCGC AGATAGCACT
TCAGCTCGGC CATCTCAGAT CCCAACTCCA GTGAATAACA ACACAAAGAA GCGAGATTCC
AAAACTGACA GCACAGAATC CAGTGGAACC CAAAGTCCTA AGCGCCATTC TGGGTCTTAC
CTTGTGACAT CTGTTTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu16786
Clone ID Related Accession (Same CDS sequence) NM_000038 , NM_001127510
Accession Version NM_001127510.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 8532bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 21-MAY-2015
Organism Homo sapiens (human)
Product adenomatous polyposis coli protein isoform b
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA795663.1, AB210001.1 and CA313732.1. On Sep 17, 2010 this sequence version replaced gi:189011565. Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. This variant also contains an alternate in-frame exon compared to variant 1. The encoded isoform (b) has a distinct N-terminus and is longer than isoform a. Variants 2 and 3 encode the same isoform (b). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB210001.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2157437, SAMEA962344 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
3481
3541
3601
3661
3721
3781
3841
3901
3961
4021
4081
4141
4201
4261
4321
4381
4441
4501
4561
4621
4681
4741
4801
4861
4921
4981
5041
5101
5161
5221
5281
5341
5401
5461
5521
5581
5641
5701
5761
5821
5881
5941
6001
6061
6121
6181
6241
6301
6361
6421
6481
6541
6601
6661
6721
6781
6841
6901
6961
7021
7081
7141
7201
7261
7321
7381
7441
7501
7561
7621
7681
7741
7801
7861
7921
7981
8041
8101
8161
8221
8281
8341
8401
8461
8521
ATGGCTGCAG CTTCATATGA TCAGTTGTTA AAGCAAGTTG AGGCACTGAA GATGGAGAAC 
TCAAATCTTC GACAAGAGCT AGAAGATAAT TCCAATCATC TTACAAAACT GGAAACTGAG
GCATCTAATA TGAAGGAAGT ACTTAAACAA CTACAAGGAA GTATTGAAGA TGAAGCTATG
GCTTCTTCTG GACAGATTGA TTTATTAGAG CGTCTTAAAG AGCTTAACTT AGATAGCAGT
AATTTCCCTG GAGTAAAACT GCGGTCAAAA ATGTCCCTCC GTTCTTATGG AAGCCGGGAA
GGATCTGTAT CAAGCCGTTC TGGAGAGTGC AGTCCTGTTC CTATGGGTTC ATTTCCAAGA
AGAGGGTTTG TAAATGGAAG CAGAGAAAGT ACTGGATATT TAGAAGAACT TGAGAAAGAG
AGGTCATTGC TTCTTGCTGA TCTTGACAAA GAAGAAAAGG AAAAAGACTG GTATTACGCT
CAACTTCAGA ATCTCACTAA AAGAATAGAT AGTCTTCCTT TAACTGAAAA TTTTTCCTTA
CAAACAGATA TGACCAGAAG GCAATTGGAA TATGAAGCAA GGCAAATCAG AGTTGCGATG
GAAGAACAAC TAGGTACCTG CCAGGATATG GAAAAACGAG CACAGCGAAG AATAGCCAGA
ATTCAGCAAA TCGAAAAGGA CATACTTCGT ATACGACAGC TTTTACAGTC CCAAGCAACA
GAAGCAGAGA GGTCATCTCA GAACAAGCAT GAAACCGGCT CACATGATGC TGAGCGGCAG
AATGAAGGTC AAGGAGTGGG AGAAATCAAC ATGGCAACTT CTGGTAATGG TCAGGGTTCA
ACTACACGAA TGGACCATGA AACAGCCAGT GTTTTGAGTT CTAGTAGCAC ACACTCTGCA
CCTCGAAGGC TGACAAGTCA TCTGGGAACC AAGGTGGAAA TGGTGTATTC ATTGTTGTCA
ATGCTTGGTA CTCATGATAA GGATGATATG TCGCGAACTT TGCTAGCTAT GTCTAGCTCC
CAAGACAGCT GTATATCCAT GCGACAGTCT GGATGTCTTC CTCTCCTCAT CCAGCTTTTA
CATGGCAATG ACAAAGACTC TGTATTGTTG GGAAATTCCC GGGGCAGTAA AGAGGCTCGG
GCCAGGGCCA GTGCAGCACT CCACAACATC ATTCACTCAC AGCCTGATGA CAAGAGAGGC
AGGCGTGAAA TCCGAGTCCT TCATCTTTTG GAACAGATAC GCGCTTACTG TGAAACCTGT
TGGGAGTGGC AGGAAGCTCA TGAACCAGGC ATGGACCAGG ACAAAAATCC AATGCCAGCT
CCTGTTGAAC ATCAGATCTG TCCTGCTGTG TGTGTTCTAA TGAAACTTTC ATTTGATGAA
GAGCATAGAC ATGCAATGAA TGAACTAGGG GGACTACAGG CCATTGCAGA ATTATTGCAA
GTGGACTGTG AAATGTATGG GCTTACTAAT GACCACTACA GTATTACACT AAGACGATAT
GCTGGAATGG CTTTGACAAA CTTGACTTTT GGAGATGTAG CCAACAAGGC TACGCTATGC
TCTATGAAAG GCTGCATGAG AGCACTTGTG GCCCAACTAA AATCTGAAAG TGAAGACTTA
CAGCAGGTTA TTGCGAGTGT TTTGAGGAAT TTGTCTTGGC GAGCAGATGT AAATAGTAAA
AAGACGTTGC GAGAAGTTGG AAGTGTGAAA GCATTGATGG AATGTGCTTT AGAAGTTAAA
AAGGAATCAA CCCTCAAAAG CGTATTGAGT GCCTTATGGA ATTTGTCAGC ACATTGCACT
GAGAATAAAG CTGATATATG TGCTGTAGAT GGTGCACTTG CATTTTTGGT TGGCACTCTT
ACTTACCGGA GCCAGACAAA CACTTTAGCC ATTATTGAAA GTGGAGGTGG GATATTACGG
AATGTGTCCA GCTTGATAGC TACAAATGAG GACCACAGGC AAATCCTAAG AGAGAACAAC
TGTCTACAAA CTTTATTACA ACACTTAAAA TCTCATAGTT TGACAATAGT CAGTAATGCA
TGTGGAACTT TGTGGAATCT CTCAGCAAGA AATCCTAAAG ACCAGGAAGC ATTATGGGAC
ATGGGGGCAG TTAGCATGCT CAAGAACCTC ATTCATTCAA AGCACAAAAT GATTGCTATG
GGAAGTGCTG CAGCTTTAAG GAATCTCATG GCAAATAGGC CTGCGAAGTA CAAGGATGCC
AATATTATGT CTCCTGGCTC AAGCTTGCCA TCTCTTCATG TTAGGAAACA AAAAGCCCTA
GAAGCAGAAT TAGATGCTCA GCACTTATCA GAAACTTTTG ACAATATAGA CAATTTAAGT
CCCAAGGCAT CTCATCGTAG TAAGCAGAGA CACAAGCAAA GTCTCTATGG TGATTATGTT
TTTGACACCA ATCGACATGA TGATAATAGG TCAGACAATT TTAATACTGG CAACATGACT
GTCCTTTCAC CATATTTGAA TACTACAGTG TTACCCAGCT CCTCTTCATC AAGAGGAAGC
TTAGATAGTT CTCGTTCTGA AAAAGATAGA AGTTTGGAGA GAGAACGCGG AATTGGTCTA
GGCAACTACC ATCCAGCAAC AGAAAATCCA GGAACTTCTT CAAAGCGAGG TTTGCAGATC
TCCACCACTG CAGCCCAGAT TGCCAAAGTC ATGGAAGAAG TGTCAGCCAT TCATACCTCT
CAGGAAGACA GAAGTTCTGG GTCTACCACT GAATTACATT GTGTGACAGA TGAGAGAAAT
GCACTTAGAA GAAGCTCTGC TGCCCATACA CATTCAAACA CTTACAATTT CACTAAGTCG
GAAAATTCAA ATAGGACATG TTCTATGCCT TATGCCAAAT TAGAATACAA GAGATCTTCA
AATGATAGTT TAAATAGTGT CAGTAGTAGT GATGGTTATG GTAAAAGAGG TCAAATGAAA
CCCTCGATTG AATCCTATTC TGAAGATGAT GAAAGTAAGT TTTGCAGTTA TGGTCAATAC
CCAGCCGACC TAGCCCATAA AATACATAGT GCAAATCATA TGGATGATAA TGATGGAGAA
CTAGATACAC CAATAAATTA TAGTCTTAAA TATTCAGATG AGCAGTTGAA CTCTGGAAGG
CAAAGTCCTT CACAGAATGA AAGATGGGCA AGACCCAAAC ACATAATAGA AGATGAAATA
AAACAAAGTG AGCAAAGACA ATCAAGGAAT CAAAGTACAA CTTATCCTGT TTATACTGAG
AGCACTGATG ATAAACACCT CAAGTTCCAA CCACATTTTG GACAGCAGGA ATGTGTTTCT
CCATACAGGT CACGGGGAGC CAATGGTTCA GAAACAAATC GAGTGGGTTC TAATCATGGA
ATTAATCAAA ATGTAAGCCA GTCTTTGTGT CAAGAAGATG ACTATGAAGA TGATAAGCCT
ACCAATTATA GTGAACGTTA CTCTGAAGAA GAACAGCATG AAGAAGAAGA GAGACCAACA
AATTATAGCA TAAAATATAA TGAAGAGAAA CGTCATGTGG ATCAGCCTAT TGATTATAGT
TTAAAATATG CCACAGATAT TCCTTCATCA CAGAAACAGT CATTTTCATT CTCAAAGAGT
TCATCTGGAC AAAGCAGTAA AACCGAACAT ATGTCTTCAA GCAGTGAGAA TACGTCCACA
CCTTCATCTA ATGCCAAGAG GCAGAATCAG CTCCATCCAA GTTCTGCACA GAGTAGAAGT
GGTCAGCCTC AAAAGGCTGC CACTTGCAAA GTTTCTTCTA TTAACCAAGA AACAATACAG
ACTTATTGTG TAGAAGATAC TCCAATATGT TTTTCAAGAT GTAGTTCATT ATCATCTTTG
TCATCAGCTG AAGATGAAAT AGGATGTAAT CAGACGACAC AGGAAGCAGA TTCTGCTAAT
ACCCTGCAAA TAGCAGAAAT AAAAGAAAAG ATTGGAACTA GGTCAGCTGA AGATCCTGTG
AGCGAAGTTC CAGCAGTGTC ACAGCACCCT AGAACCAAAT CCAGCAGACT GCAGGGTTCT
AGTTTATCTT CAGAATCAGC CAGGCACAAA GCTGTTGAAT TTTCTTCAGG AGCGAAATCT
CCCTCCAAAA GTGGTGCTCA GACACCCAAA AGTCCACCTG AACACTATGT TCAGGAGACC
CCACTCATGT TTAGCAGATG TACTTCTGTC AGTTCACTTG ATAGTTTTGA GAGTCGTTCG
ATTGCCAGCT CCGTTCAGAG TGAACCATGC AGTGGAATGG TAAGTGGCAT TATAAGCCCC
AGTGATCTTC CAGATAGCCC TGGACAAACC ATGCCACCAA GCAGAAGTAA AACACCTCCA
CCACCTCCTC AAACAGCTCA AACCAAGCGA GAAGTACCTA AAAATAAAGC ACCTACTGCT
GAAAAGAGAG AGAGTGGACC TAAGCAAGCT GCAGTAAATG CTGCAGTTCA GAGGGTCCAG
GTTCTTCCAG ATGCTGATAC TTTATTACAT TTTGCCACGG AAAGTACTCC AGATGGATTT
TCTTGTTCAT CCAGCCTGAG TGCTCTGAGC CTCGATGAGC CATTTATACA GAAAGATGTG
GAATTAAGAA TAATGCCTCC AGTTCAGGAA AATGACAATG GGAATGAAAC AGAATCAGAG
CAGCCTAAAG AATCAAATGA AAACCAAGAG AAAGAGGCAG AAAAAACTAT TGATTCTGAA
AAGGACCTAT TAGATGATTC AGATGATGAT GATATTGAAA TACTAGAAGA ATGTATTATT
TCTGCCATGC CAACAAAGTC ATCACGTAAA GCAAAAAAGC CAGCCCAGAC TGCTTCAAAA
TTACCTCCAC CTGTGGCAAG GAAACCAAGT CAGCTGCCTG TGTACAAACT TCTACCATCA
CAAAACAGGT TGCAACCCCA AAAGCATGTT AGTTTTACAC CGGGGGATGA TATGCCACGG
GTGTATTGTG TTGAAGGGAC ACCTATAAAC TTTTCCACAG CTACATCTCT AAGTGATCTA
ACAATCGAAT CCCCTCCAAA TGAGTTAGCT GCTGGAGAAG GAGTTAGAGG AGGGGCACAG
TCAGGTGAAT TTGAAAAACG AGATACCATT CCTACAGAAG GCAGAAGTAC AGATGAGGCT
CAAGGAGGAA AAACCTCATC TGTAACCATA CCTGAATTGG ATGACAATAA AGCAGAGGAA
GGTGATATTC TTGCAGAATG CATTAATTCT GCTATGCCCA AAGGGAAAAG TCACAAGCCT
TTCCGTGTGA AAAAGATAAT GGACCAGGTC CAGCAAGCAT CTGCGTCTTC TTCTGCACCC
AACAAAAATC AGTTAGATGG TAAGAAAAAG AAACCAACTT CACCAGTAAA ACCTATACCA
CAAAATACTG AATATAGGAC ACGTGTAAGA AAAAATGCAG ACTCAAAAAA TAATTTAAAT
GCTGAGAGAG TTTTCTCAGA CAACAAAGAT TCAAAGAAAC AGAATTTGAA AAATAATTCC
AAGGTCTTCA ATGATAAGCT CCCAAATAAT GAAGATAGAG TCAGAGGAAG TTTTGCTTTT
GATTCACCTC ATCATTACAC GCCTATTGAA GGAACTCCTT ACTGTTTTTC ACGAAATGAT
TCTTTGAGTT CTCTAGATTT TGATGATGAT GATGTTGACC TTTCCAGGGA AAAGGCTGAA
TTAAGAAAGG CAAAAGAAAA TAAGGAATCA GAGGCTAAAG TTACCAGCCA CACAGAACTA
ACCTCCAACC AACAATCAGC TAATAAGACA CAAGCTATTG CAAAGCAGCC AATAAATCGA
GGTCAGCCTA AACCCATACT TCAGAAACAA TCCACTTTTC CCCAGTCATC CAAAGACATA
CCAGACAGAG GGGCAGCAAC TGATGAAAAG TTACAGAATT TTGCTATTGA AAATACTCCG
GTTTGCTTTT CTCATAATTC CTCTCTGAGT TCTCTCAGTG ACATTGACCA AGAAAACAAC
AATAAAGAAA ATGAACCTAT CAAAGAGACT GAGCCCCCTG ACTCACAGGG AGAACCAAGT
AAACCTCAAG CATCAGGCTA TGCTCCTAAA TCATTTCATG TTGAAGATAC CCCAGTTTGT
TTCTCAAGAA ACAGTTCTCT CAGTTCTCTT AGTATTGACT CTGAAGATGA CCTGTTGCAG
GAATGTATAA GCTCCGCAAT GCCAAAAAAG AAAAAGCCTT CAAGACTCAA GGGTGATAAT
GAAAAACATA GTCCCAGAAA TATGGGTGGC ATATTAGGTG AAGATCTGAC ACTTGATTTG
AAAGATATAC AGAGACCAGA TTCAGAACAT GGTCTATCCC CTGATTCAGA AAATTTTGAT
TGGAAAGCTA TTCAGGAAGG TGCAAATTCC ATAGTAAGTA GTTTACATCA AGCTGCTGCT
GCTGCATGTT TATCTAGACA AGCTTCGTCT GATTCAGATT CCATCCTTTC CCTGAAATCA
GGAATCTCTC TGGGATCACC ATTTCATCTT ACACCTGATC AAGAAGAAAA ACCCTTTACA
AGTAATAAAG GCCCACGAAT TCTAAAACCA GGGGAGAAAA GTACATTGGA AACTAAAAAG
ATAGAATCTG AAAGTAAAGG AATCAAAGGA GGAAAAAAAG TTTATAAAAG TTTGATTACT
GGAAAAGTTC GATCTAATTC AGAAATTTCA GGCCAAATGA AACAGCCCCT TCAAGCAAAC
ATGCCTTCAA TCTCTCGAGG CAGGACAATG ATTCATATTC CAGGAGTTCG AAATAGCTCC
TCAAGTACAA GTCCTGTTTC TAAAAAAGGC CCACCCCTTA AGACTCCAGC CTCCAAAAGC
CCTAGTGAAG GTCAAACAGC CACCACTTCT CCTAGAGGAG CCAAGCCATC TGTGAAATCA
GAATTAAGCC CTGTTGCCAG GCAGACATCC CAAATAGGTG GGTCAAGTAA AGCACCTTCT
AGATCAGGAT CTAGAGATTC GACCCCTTCA AGACCTGCCC AGCAACCATT AAGTAGACCT
ATACAGTCTC CTGGCCGAAA CTCAATTTCC CCTGGTAGAA ATGGAATAAG TCCTCCTAAC
AAATTATCTC AACTTCCAAG GACATCATCC CCTAGTACTG CTTCAACTAA GTCCTCAGGT
TCTGGAAAAA TGTCATATAC ATCTCCAGGT AGACAGATGA GCCAACAGAA CCTTACCAAA
CAAACAGGTT TATCCAAGAA TGCCAGTAGT ATTCCAAGAA GTGAGTCTGC CTCCAAAGGA
CTAAATCAGA TGAATAATGG TAATGGAGCC AATAAAAAGG TAGAACTTTC TAGAATGTCT
TCAACTAAAT CAAGTGGAAG TGAATCTGAT AGATCAGAAA GACCTGTATT AGTACGCCAG
TCAACTTTCA TCAAAGAAGC TCCAAGCCCA ACCTTAAGAA GAAAATTGGA GGAATCTGCT
TCATTTGAAT CTCTTTCTCC ATCATCTAGA CCAGCTTCTC CCACTAGGTC CCAGGCACAA
ACTCCAGTTT TAAGTCCTTC CCTTCCTGAT ATGTCTCTAT CCACACATTC GTCTGTTCAG
GCTGGTGGAT GGCGAAAACT CCCACCTAAT CTCAGTCCCA CTATAGAGTA TAATGATGGA
AGACCAGCAA AGCGCCATGA TATTGCACGG TCTCATTCTG AAAGTCCTTC TAGACTTCCA
ATCAATAGGT CAGGAACCTG GAAACGTGAG CACAGCAAAC ATTCATCATC CCTTCCTCGA
GTAAGCACTT GGAGAAGAAC TGGAAGTTCA TCTTCAATTC TTTCTGCTTC ATCAGAATCC
AGTGAAAAAG CAAAAAGTGA GGATGAAAAA CATGTGAACT CTATTTCAGG AACCAAACAA
AGTAAAGAAA ACCAAGTATC CGCAAAAGGA ACATGGAGAA AAATAAAAGA AAATGAATTT
TCTCCCACAA ATAGTACTTC TCAGACCGTT TCCTCAGGTG CTACAAATGG TGCTGAATCA
AAGACTCTAA TTTATCAAAT GGCACCTGCT GTTTCTAAAA CAGAGGATGT TTGGGTGAGA
ATTGAGGACT GTCCCATTAA CAATCCTAGA TCTGGAAGAT CTCCCACAGG TAATACTCCC
CCGGTGATTG ACAGTGTTTC AGAAAAGGCA AATCCAAACA TTAAAGATTC AAAAGATAAT
CAGGCAAAAC AAAATGTGGG TAATGGCAGT GTTCCCATGC GTACCGTGGG TTTGGAAAAT
CGCCTGAACT CCTTTATTCA GGTGGATGCC CCTGACCAAA AAGGAACTGA GATAAAACCA
GGACAAAATA ATCCTGTCCC TGTATCAGAG ACTAATGAAA GTTCTATAGT GGAACGTACC
CCATTCAGTT CTAGCAGCTC AAGCAAACAC AGTTCACCTA GTGGGACTGT TGCTGCCAGA
GTGACTCCTT TTAATTACAA CCCAAGCCCT AGGAAAAGCA GCGCAGATAG CACTTCAGCT
CGGCCATCTC AGATCCCAAC TCCAGTGAAT AACAACACAA AGAAGCGAGA TTCCAAAACT
GACAGCACAG AATCCAGTGG AACCCAAAGT CCTAAGCGCC ATTCTGGGTC TTACCTTGTG
ACATCTGTTT AA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001120982.1
CDS194..8725
Misc Feature(1)185..187(+)
Misc Feature(2)197..199(+)
Misc Feature(3)569..817(+)
Misc Feature(4)1124..1432(+)
Misc Feature(5)1184..1360(+)
Misc Feature(6)1550..1678(+)
Misc Feature(7)1583..1984(+)
Misc Feature(8)1688..1984(+)
Misc Feature(9)1706..1834(+)
Misc Feature(10)1835..1966(+)
Misc Feature(11)1967..2107(+)
Misc Feature(12)2024..2386(+)
Misc Feature(13)2090..2386(+)
Misc Feature(14)2108..2242(+)
Misc Feature(15)2243..2368(+)
Misc Feature(16)2369..2494(+)
Misc Feature(17)2423..2425(+)
Misc Feature(18)2531..2533(+)
Misc Feature(19)3071..4204(+)
Misc Feature(20)3317..3319(+)
Misc Feature(21)4271..4273(+)
Misc Feature(22)4298..4375(+)
Misc Feature(23)5099..5176(+)
Misc Feature(24)5348..5407(+)
Misc Feature(25)5774..5776(+)
Misc Feature(26)5780..5782(+)
Misc Feature(27)5783..5785(+)
Misc Feature(28)5789..5872(+)
Misc Feature(29)6293..6352(+)
Misc Feature(30)6644..6646(+)
Misc Feature(31)6860..7897(+)
Misc Feature(32)6971..6973(+)
Misc Feature(33)7001..7003(+)
Misc Feature(34)7040..7042(+)
Misc Feature(35)7610..7612(+)
Misc Feature(36)7796..7798(+)
Misc Feature(37)8201..8722(+)
Misc Feature(38)8204..8206(+)
Misc Feature(39)8213..8215(+)
Misc Feature(40)8228..8230(+)
Misc Feature(41)8558..8560(+)
Misc Feature(42)8600..8611(+)
Misc Feature(43)8714..8722(+)
Exon (1)1..67
Gene:APC
Gene Synonym:
Exon (2)68..175
Gene:APC
Gene Synonym:
Exon (3)176..328
Gene:APC
Gene Synonym:
Exon (4)329..413
Gene:APC
Gene Synonym:
Exon (5)414..615
Gene:APC
Gene Synonym:
Exon (6)616..724
Gene:APC
Gene Synonym:
Exon (7)725..838
Gene:APC
Gene Synonym:
Exon (8)839..922
Gene:APC
Gene Synonym:
Exon (9)923..1027
Gene:APC
Gene Synonym:
Exon (10)1028..1126
Gene:APC
Gene Synonym:
Exon (11)1127..1505
Gene:APC
Gene Synonym:
Exon (12)1506..1601
Gene:APC
Gene Synonym:
Exon (13)1602..1741
Gene:APC
Gene Synonym:
Exon (14)1742..1819
Gene:APC
Gene Synonym:
Exon (15)1820..1936
Gene:APC
Gene Synonym:
Exon (16)1937..2151
Gene:APC
Gene Synonym:
Exon (17)2152..10838
Gene:APC
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001127510
Organism Homo sapiens (human)
Definition Homo sapiens adenomatous polyposis coli (APC), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001127510

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
3481
3541
3601
3661
3721
3781
3841
3901
3961
4021
4081
4141
4201
4261
4321
4381
4441
4501
4561
4621
4681
4741
4801
4861
4921
4981
5041
5101
5161
5221
5281
5341
5401
5461
5521
5581
5641
5701
5761
5821
5881
5941
6001
6061
6121
6181
6241
6301
6361
6421
6481
6541
6601
6661
6721
6781
6841
6901
6961
7021
7081
7141
7201
7261
7321
7381
7441
7501
7561
7621
7681
7741
7801
7861
7921
7981
8041
8101
8161
8221
8281
8341
8401
8461
8521
ATGGCTGCAG CTTCATATGA TCAGTTGTTA AAGCAAGTTG AGGCACTGAA GATGGAGAAC 
TCAAATCTTC GACAAGAGCT AGAAGATAAT TCCAATCATC TTACAAAACT GGAAACTGAG
GCATCTAATA TGAAGGAAGT ACTTAAACAA CTACAAGGAA GTATTGAAGA TGAAGCTATG
GCTTCTTCTG GACAGATTGA TTTATTAGAG CGTCTTAAAG AGCTTAACTT AGATAGCAGT
AATTTCCCTG GAGTAAAACT GCGGTCAAAA ATGTCCCTCC GTTCTTATGG AAGCCGGGAA
GGATCTGTAT CAAGCCGTTC TGGAGAGTGC AGTCCTGTTC CTATGGGTTC ATTTCCAAGA
AGAGGGTTTG TAAATGGAAG CAGAGAAAGT ACTGGATATT TAGAAGAACT TGAGAAAGAG
AGGTCATTGC TTCTTGCTGA TCTTGACAAA GAAGAAAAGG AAAAAGACTG GTATTACGCT
CAACTTCAGA ATCTCACTAA AAGAATAGAT AGTCTTCCTT TAACTGAAAA TTTTTCCTTA
CAAACAGATA TGACCAGAAG GCAATTGGAA TATGAAGCAA GGCAAATCAG AGTTGCGATG
GAAGAACAAC TAGGTACCTG CCAGGATATG GAAAAACGAG CACAGCGAAG AATAGCCAGA
ATTCAGCAAA TCGAAAAGGA CATACTTCGT ATACGACAGC TTTTACAGTC CCAAGCAACA
GAAGCAGAGA GGTCATCTCA GAACAAGCAT GAAACCGGCT CACATGATGC TGAGCGGCAG
AATGAAGGTC AAGGAGTGGG AGAAATCAAC ATGGCAACTT CTGGTAATGG TCAGGGTTCA
ACTACACGAA TGGACCATGA AACAGCCAGT GTTTTGAGTT CTAGTAGCAC ACACTCTGCA
CCTCGAAGGC TGACAAGTCA TCTGGGAACC AAGGTGGAAA TGGTGTATTC ATTGTTGTCA
ATGCTTGGTA CTCATGATAA GGATGATATG TCGCGAACTT TGCTAGCTAT GTCTAGCTCC
CAAGACAGCT GTATATCCAT GCGACAGTCT GGATGTCTTC CTCTCCTCAT CCAGCTTTTA
CATGGCAATG ACAAAGACTC TGTATTGTTG GGAAATTCCC GGGGCAGTAA AGAGGCTCGG
GCCAGGGCCA GTGCAGCACT CCACAACATC ATTCACTCAC AGCCTGATGA CAAGAGAGGC
AGGCGTGAAA TCCGAGTCCT TCATCTTTTG GAACAGATAC GCGCTTACTG TGAAACCTGT
TGGGAGTGGC AGGAAGCTCA TGAACCAGGC ATGGACCAGG ACAAAAATCC AATGCCAGCT
CCTGTTGAAC ATCAGATCTG TCCTGCTGTG TGTGTTCTAA TGAAACTTTC ATTTGATGAA
GAGCATAGAC ATGCAATGAA TGAACTAGGG GGACTACAGG CCATTGCAGA ATTATTGCAA
GTGGACTGTG AAATGTATGG GCTTACTAAT GACCACTACA GTATTACACT AAGACGATAT
GCTGGAATGG CTTTGACAAA CTTGACTTTT GGAGATGTAG CCAACAAGGC TACGCTATGC
TCTATGAAAG GCTGCATGAG AGCACTTGTG GCCCAACTAA AATCTGAAAG TGAAGACTTA
CAGCAGGTTA TTGCGAGTGT TTTGAGGAAT TTGTCTTGGC GAGCAGATGT AAATAGTAAA
AAGACGTTGC GAGAAGTTGG AAGTGTGAAA GCATTGATGG AATGTGCTTT AGAAGTTAAA
AAGGAATCAA CCCTCAAAAG CGTATTGAGT GCCTTATGGA ATTTGTCAGC ACATTGCACT
GAGAATAAAG CTGATATATG TGCTGTAGAT GGTGCACTTG CATTTTTGGT TGGCACTCTT
ACTTACCGGA GCCAGACAAA CACTTTAGCC ATTATTGAAA GTGGAGGTGG GATATTACGG
AATGTGTCCA GCTTGATAGC TACAAATGAG GACCACAGGC AAATCCTAAG AGAGAACAAC
TGTCTACAAA CTTTATTACA ACACTTAAAA TCTCATAGTT TGACAATAGT CAGTAATGCA
TGTGGAACTT TGTGGAATCT CTCAGCAAGA AATCCTAAAG ACCAGGAAGC ATTATGGGAC
ATGGGGGCAG TTAGCATGCT CAAGAACCTC ATTCATTCAA AGCACAAAAT GATTGCTATG
GGAAGTGCTG CAGCTTTAAG GAATCTCATG GCAAATAGGC CTGCGAAGTA CAAGGATGCC
AATATTATGT CTCCTGGCTC AAGCTTGCCA TCTCTTCATG TTAGGAAACA AAAAGCCCTA
GAAGCAGAAT TAGATGCTCA GCACTTATCA GAAACTTTTG ACAATATAGA CAATTTAAGT
CCCAAGGCAT CTCATCGTAG TAAGCAGAGA CACAAGCAAA GTCTCTATGG TGATTATGTT
TTTGACACCA ATCGACATGA TGATAATAGG TCAGACAATT TTAATACTGG CAACATGACT
GTCCTTTCAC CATATTTGAA TACTACAGTG TTACCCAGCT CCTCTTCATC AAGAGGAAGC
TTAGATAGTT CTCGTTCTGA AAAAGATAGA AGTTTGGAGA GAGAACGCGG AATTGGTCTA
GGCAACTACC ATCCAGCAAC AGAAAATCCA GGAACTTCTT CAAAGCGAGG TTTGCAGATC
TCCACCACTG CAGCCCAGAT TGCCAAAGTC ATGGAAGAAG TGTCAGCCAT TCATACCTCT
CAGGAAGACA GAAGTTCTGG GTCTACCACT GAATTACATT GTGTGACAGA TGAGAGAAAT
GCACTTAGAA GAAGCTCTGC TGCCCATACA CATTCAAACA CTTACAATTT CACTAAGTCG
GAAAATTCAA ATAGGACATG TTCTATGCCT TATGCCAAAT TAGAATACAA GAGATCTTCA
AATGATAGTT TAAATAGTGT CAGTAGTAGT GATGGTTATG GTAAAAGAGG TCAAATGAAA
CCCTCGATTG AATCCTATTC TGAAGATGAT GAAAGTAAGT TTTGCAGTTA TGGTCAATAC
CCAGCCGACC TAGCCCATAA AATACATAGT GCAAATCATA TGGATGATAA TGATGGAGAA
CTAGATACAC CAATAAATTA TAGTCTTAAA TATTCAGATG AGCAGTTGAA CTCTGGAAGG
CAAAGTCCTT CACAGAATGA AAGATGGGCA AGACCCAAAC ACATAATAGA AGATGAAATA
AAACAAAGTG AGCAAAGACA ATCAAGGAAT CAAAGTACAA CTTATCCTGT TTATACTGAG
AGCACTGATG ATAAACACCT CAAGTTCCAA CCACATTTTG GACAGCAGGA ATGTGTTTCT
CCATACAGGT CACGGGGAGC CAATGGTTCA GAAACAAATC GAGTGGGTTC TAATCATGGA
ATTAATCAAA ATGTAAGCCA GTCTTTGTGT CAAGAAGATG ACTATGAAGA TGATAAGCCT
ACCAATTATA GTGAACGTTA CTCTGAAGAA GAACAGCATG AAGAAGAAGA GAGACCAACA
AATTATAGCA TAAAATATAA TGAAGAGAAA CGTCATGTGG ATCAGCCTAT TGATTATAGT
TTAAAATATG CCACAGATAT TCCTTCATCA CAGAAACAGT CATTTTCATT CTCAAAGAGT
TCATCTGGAC AAAGCAGTAA AACCGAACAT ATGTCTTCAA GCAGTGAGAA TACGTCCACA
CCTTCATCTA ATGCCAAGAG GCAGAATCAG CTCCATCCAA GTTCTGCACA GAGTAGAAGT
GGTCAGCCTC AAAAGGCTGC CACTTGCAAA GTTTCTTCTA TTAACCAAGA AACAATACAG
ACTTATTGTG TAGAAGATAC TCCAATATGT TTTTCAAGAT GTAGTTCATT ATCATCTTTG
TCATCAGCTG AAGATGAAAT AGGATGTAAT CAGACGACAC AGGAAGCAGA TTCTGCTAAT
ACCCTGCAAA TAGCAGAAAT AAAAGAAAAG ATTGGAACTA GGTCAGCTGA AGATCCTGTG
AGCGAAGTTC CAGCAGTGTC ACAGCACCCT AGAACCAAAT CCAGCAGACT GCAGGGTTCT
AGTTTATCTT CAGAATCAGC CAGGCACAAA GCTGTTGAAT TTTCTTCAGG AGCGAAATCT
CCCTCCAAAA GTGGTGCTCA GACACCCAAA AGTCCACCTG AACACTATGT TCAGGAGACC
CCACTCATGT TTAGCAGATG TACTTCTGTC AGTTCACTTG ATAGTTTTGA GAGTCGTTCG
ATTGCCAGCT CCGTTCAGAG TGAACCATGC AGTGGAATGG TAAGTGGCAT TATAAGCCCC
AGTGATCTTC CAGATAGCCC TGGACAAACC ATGCCACCAA GCAGAAGTAA AACACCTCCA
CCACCTCCTC AAACAGCTCA AACCAAGCGA GAAGTACCTA AAAATAAAGC ACCTACTGCT
GAAAAGAGAG AGAGTGGACC TAAGCAAGCT GCAGTAAATG CTGCAGTTCA GAGGGTCCAG
GTTCTTCCAG ATGCTGATAC TTTATTACAT TTTGCCACGG AAAGTACTCC AGATGGATTT
TCTTGTTCAT CCAGCCTGAG TGCTCTGAGC CTCGATGAGC CATTTATACA GAAAGATGTG
GAATTAAGAA TAATGCCTCC AGTTCAGGAA AATGACAATG GGAATGAAAC AGAATCAGAG
CAGCCTAAAG AATCAAATGA AAACCAAGAG AAAGAGGCAG AAAAAACTAT TGATTCTGAA
AAGGACCTAT TAGATGATTC AGATGATGAT GATATTGAAA TACTAGAAGA ATGTATTATT
TCTGCCATGC CAACAAAGTC ATCACGTAAA GCAAAAAAGC CAGCCCAGAC TGCTTCAAAA
TTACCTCCAC CTGTGGCAAG GAAACCAAGT CAGCTGCCTG TGTACAAACT TCTACCATCA
CAAAACAGGT TGCAACCCCA AAAGCATGTT AGTTTTACAC CGGGGGATGA TATGCCACGG
GTGTATTGTG TTGAAGGGAC ACCTATAAAC TTTTCCACAG CTACATCTCT AAGTGATCTA
ACAATCGAAT CCCCTCCAAA TGAGTTAGCT GCTGGAGAAG GAGTTAGAGG AGGGGCACAG
TCAGGTGAAT TTGAAAAACG AGATACCATT CCTACAGAAG GCAGAAGTAC AGATGAGGCT
CAAGGAGGAA AAACCTCATC TGTAACCATA CCTGAATTGG ATGACAATAA AGCAGAGGAA
GGTGATATTC TTGCAGAATG CATTAATTCT GCTATGCCCA AAGGGAAAAG TCACAAGCCT
TTCCGTGTGA AAAAGATAAT GGACCAGGTC CAGCAAGCAT CTGCGTCTTC TTCTGCACCC
AACAAAAATC AGTTAGATGG TAAGAAAAAG AAACCAACTT CACCAGTAAA ACCTATACCA
CAAAATACTG AATATAGGAC ACGTGTAAGA AAAAATGCAG ACTCAAAAAA TAATTTAAAT
GCTGAGAGAG TTTTCTCAGA CAACAAAGAT TCAAAGAAAC AGAATTTGAA AAATAATTCC
AAGGTCTTCA ATGATAAGCT CCCAAATAAT GAAGATAGAG TCAGAGGAAG TTTTGCTTTT
GATTCACCTC ATCATTACAC GCCTATTGAA GGAACTCCTT ACTGTTTTTC ACGAAATGAT
TCTTTGAGTT CTCTAGATTT TGATGATGAT GATGTTGACC TTTCCAGGGA AAAGGCTGAA
TTAAGAAAGG CAAAAGAAAA TAAGGAATCA GAGGCTAAAG TTACCAGCCA CACAGAACTA
ACCTCCAACC AACAATCAGC TAATAAGACA CAAGCTATTG CAAAGCAGCC AATAAATCGA
GGTCAGCCTA AACCCATACT TCAGAAACAA TCCACTTTTC CCCAGTCATC CAAAGACATA
CCAGACAGAG GGGCAGCAAC TGATGAAAAG TTACAGAATT TTGCTATTGA AAATACTCCG
GTTTGCTTTT CTCATAATTC CTCTCTGAGT TCTCTCAGTG ACATTGACCA AGAAAACAAC
AATAAAGAAA ATGAACCTAT CAAAGAGACT GAGCCCCCTG ACTCACAGGG AGAACCAAGT
AAACCTCAAG CATCAGGCTA TGCTCCTAAA TCATTTCATG TTGAAGATAC CCCAGTTTGT
TTCTCAAGAA ACAGTTCTCT CAGTTCTCTT AGTATTGACT CTGAAGATGA CCTGTTGCAG
GAATGTATAA GCTCCGCAAT GCCAAAAAAG AAAAAGCCTT CAAGACTCAA GGGTGATAAT
GAAAAACATA GTCCCAGAAA TATGGGTGGC ATATTAGGTG AAGATCTGAC ACTTGATTTG
AAAGATATAC AGAGACCAGA TTCAGAACAT GGTCTATCCC CTGATTCAGA AAATTTTGAT
TGGAAAGCTA TTCAGGAAGG TGCAAATTCC ATAGTAAGTA GTTTACATCA AGCTGCTGCT
GCTGCATGTT TATCTAGACA AGCTTCGTCT GATTCAGATT CCATCCTTTC CCTGAAATCA
GGAATCTCTC TGGGATCACC ATTTCATCTT ACACCTGATC AAGAAGAAAA ACCCTTTACA
AGTAATAAAG GCCCACGAAT TCTAAAACCA GGGGAGAAAA GTACATTGGA AACTAAAAAG
ATAGAATCTG AAAGTAAAGG AATCAAAGGA GGAAAAAAAG TTTATAAAAG TTTGATTACT
GGAAAAGTTC GATCTAATTC AGAAATTTCA GGCCAAATGA AACAGCCCCT TCAAGCAAAC
ATGCCTTCAA TCTCTCGAGG CAGGACAATG ATTCATATTC CAGGAGTTCG AAATAGCTCC
TCAAGTACAA GTCCTGTTTC TAAAAAAGGC CCACCCCTTA AGACTCCAGC CTCCAAAAGC
CCTAGTGAAG GTCAAACAGC CACCACTTCT CCTAGAGGAG CCAAGCCATC TGTGAAATCA
GAATTAAGCC CTGTTGCCAG GCAGACATCC CAAATAGGTG GGTCAAGTAA AGCACCTTCT
AGATCAGGAT CTAGAGATTC GACCCCTTCA AGACCTGCCC AGCAACCATT AAGTAGACCT
ATACAGTCTC CTGGCCGAAA CTCAATTTCC CCTGGTAGAA ATGGAATAAG TCCTCCTAAC
AAATTATCTC AACTTCCAAG GACATCATCC CCTAGTACTG CTTCAACTAA GTCCTCAGGT
TCTGGAAAAA TGTCATATAC ATCTCCAGGT AGACAGATGA GCCAACAGAA CCTTACCAAA
CAAACAGGTT TATCCAAGAA TGCCAGTAGT ATTCCAAGAA GTGAGTCTGC CTCCAAAGGA
CTAAATCAGA TGAATAATGG TAATGGAGCC AATAAAAAGG TAGAACTTTC TAGAATGTCT
TCAACTAAAT CAAGTGGAAG TGAATCTGAT AGATCAGAAA GACCTGTATT AGTACGCCAG
TCAACTTTCA TCAAAGAAGC TCCAAGCCCA ACCTTAAGAA GAAAATTGGA GGAATCTGCT
TCATTTGAAT CTCTTTCTCC ATCATCTAGA CCAGCTTCTC CCACTAGGTC CCAGGCACAA
ACTCCAGTTT TAAGTCCTTC CCTTCCTGAT ATGTCTCTAT CCACACATTC GTCTGTTCAG
GCTGGTGGAT GGCGAAAACT CCCACCTAAT CTCAGTCCCA CTATAGAGTA TAATGATGGA
AGACCAGCAA AGCGCCATGA TATTGCACGG TCTCATTCTG AAAGTCCTTC TAGACTTCCA
ATCAATAGGT CAGGAACCTG GAAACGTGAG CACAGCAAAC ATTCATCATC CCTTCCTCGA
GTAAGCACTT GGAGAAGAAC TGGAAGTTCA TCTTCAATTC TTTCTGCTTC ATCAGAATCC
AGTGAAAAAG CAAAAAGTGA GGATGAAAAA CATGTGAACT CTATTTCAGG AACCAAACAA
AGTAAAGAAA ACCAAGTATC CGCAAAAGGA ACATGGAGAA AAATAAAAGA AAATGAATTT
TCTCCCACAA ATAGTACTTC TCAGACCGTT TCCTCAGGTG CTACAAATGG TGCTGAATCA
AAGACTCTAA TTTATCAAAT GGCACCTGCT GTTTCTAAAA CAGAGGATGT TTGGGTGAGA
ATTGAGGACT GTCCCATTAA CAATCCTAGA TCTGGAAGAT CTCCCACAGG TAATACTCCC
CCGGTGATTG ACAGTGTTTC AGAAAAGGCA AATCCAAACA TTAAAGATTC AAAAGATAAT
CAGGCAAAAC AAAATGTGGG TAATGGCAGT GTTCCCATGC GTACCGTGGG TTTGGAAAAT
CGCCTGAACT CCTTTATTCA GGTGGATGCC CCTGACCAAA AAGGAACTGA GATAAAACCA
GGACAAAATA ATCCTGTCCC TGTATCAGAG ACTAATGAAA GTTCTATAGT GGAACGTACC
CCATTCAGTT CTAGCAGCTC AAGCAAACAC AGTTCACCTA GTGGGACTGT TGCTGCCAGA
GTGACTCCTT TTAATTACAA CCCAAGCCCT AGGAAAAGCA GCGCAGATAG CACTTCAGCT
CGGCCATCTC AGATCCCAAC TCCAGTGAAT AACAACACAA AGAAGCGAGA TTCCAAAACT
GACAGCACAG AATCCAGTGG AACCCAAAGT CCTAAGCGCC ATTCTGGGTC TTACCTTGTG
ACATCTGTTT AA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

Identification of novel mutations by exome sequencing in African American colorectal cancer patients
Cancer 121 (1), 34-42 (2015)
Ashktorab H, Daremipouran M, Devaney J, Varma S, Rahi H, Lee E, Shokrani B, Schwartz R, Nickerson ML and Brim H.


book

[Analysis of APC gene mutation in a familial adenomatous polyposis pedigree]
Zhonghua Yi Xue Yi Chuan Xue Za Zhi 31 (6), 757-760 (2014)
Zhang M, Wang Z, Lin Y, Lin Y, Li X, Yan A, Fu X, Zhong F and Lan F.


book

Promoter methylation analysis of WNT/beta-catenin pathway regulators and its association with expression of DNMT1 enzyme in colorectal cancer
J. Biomed. Sci. 21, 73 (2014)
Samaei NM, Yazdani Y, Alizadeh-Navaei R, Azadeh H and Farazmandfar T.


book

Identification of an alternative 5' untranslated region of the adenomatous polyposis coli gene
Hum. Genet. 90 (6), 650-652 (1993)
Lambertz S and Ballhausen WG.


book

APC-Associated Polyposis Conditions
(in) Pagon RA, Adam MP, Ardinger HH, Wallace SE, Amemiya A, Bean LJH, Bird TD, Dolan CR, Fong CT, Smith RJH and Stephens K (Eds.); GENEREVIEWS(R); (1993)
Jasperson,K.W. and Burt,R.W.


book

Somatic mutation of the APC gene in gastric cancer: frequent mutations in very well differentiated adenocarcinoma and signet-ring cell carcinoma
Hum. Mol. Genet. 1 (8), 559-563 (1992)
Nakatsuru S, Yanagisawa A, Ichii S, Tahara E, Kato Y, Nakamura Y and Horii A.


book

Disruption of the APC gene by a retrotransposal insertion of L1 sequence in a colon cancer
Cancer Res. 52 (3), 643-645 (1992)
Miki Y, Nishisho I, Horii A, Miyoshi Y, Utsunomiya J, Kinzler KW, Vogelstein B and Nakamura Y.


book

Screening for germ-line mutations in familial adenomatous polyposis patients: 61 new patients and a summary of 150 unrelated patients
Hum. Mutat. 1 (6), 467-473 (1992)
Nagase H, Miyoshi Y, Horii A, Aoki T, Petersen GM, Vogelstein B, Maher E, Ogawa M, Maruyama M, Utsunomiya J et al.


book

Mutations of chromosome 5q21 genes in FAP and colorectal cancer patients
Science 253 (5020), 665-669 (1991)
Nishisho I, Nakamura Y, Miyoshi Y, Miki Y, Ando H, Horii A, Koyama K, Utsunomiya J, Baba S and Hedge P.


book

Identification of FAP locus genes from chromosome 5q21
Science 253 (5020), 661-665 (1991)
Kinzler KW, Nilbert MC, Su LK, Vogelstein B, Bryan TM, Levy DB, Smith KJ, Preisinger AC, Hedge P, McKechnie D et al.


 
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