The following HSPA1A gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the HSPA1A gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
||ORF Nucleotide Sequence (Length: 1926bp)
||pcDNA3.1+/C-(K)DYK or customized vector
|Tag on pcDNA3.1+/C-(K)DYK
||C terminal DYKDDDDK tags
|ORF Insert Method
||CloneEZ® Seamless cloning technology
||Homo sapiens (human)
||heat shock 70 kDa protein 1A/1B
||REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from DA486842.1, AK225692.1,
DA256622.1, AK096017.1 and BC002453.2.
On Jul 15, 2008 this sequence version replaced gi:26787973.
Summary: This intronless gene encodes a 70kDa heat shock protein
which is a member of the heat shock protein 70 family. In
conjuction with other heat shock proteins, this protein stabilizes
existing proteins against aggregation and mediates the folding of
newly translated proteins in the cytosol and in organelles. It is
also involved in the ubiquitin-proteasome pathway through
interaction with the AU-rich element RNA-binding protein 1. The
gene is located in the major histocompatibility complex class III
region, in a cluster with two closely related genes which encode
similar proteins. [provided by RefSeq, Jul 2008].
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
COMPLETENESS: complete on the 3' end.