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IFNA6 cDNA ORF clone, Homo sapiens (human)

Gene Symbol IFNA6
Entrez Gene ID 3443
Full Name interferon, alpha 6
Synonyms IFN-alphaK
General protein information
Preferred Names
interferon alpha-6
Names
interferon alpha-6
leIF K
IFN-alpha-6
interferon alpha-K
interferon alpha-54
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

9

9p22

Summary lac of sum
Disorder MIM:

147566


mRNA and Protein(s)

mRNA Protein Name
NM_021002 NP_066282 interferon alpha-6 precursor



Homo sapiens (human) IFNA6 NP_066282.1
Pan troglodytes (chimpanzee) IFNA6 XP_528566.1
Macaca mulatta (Rhesus monkey) LOC710707 XP_001099374.1


GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following IFNA6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the IFNA6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu32296
NM_021002 Homo sapiens interferon, alpha 6 (IFNA6), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$49.50-$69.30
$99.00
Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
5 or more Clone 50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu32296
Clone ID Related Accession (Same CDS sequence) NM_021002
Accession Version NM_021002.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 570bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 03-FEB-2014
Organism Homo sapiens (human)
Product interferon alpha-6 precursor
Comment VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL353732.14. On Mar 24, 2010 this sequence version replaced gi:11128014. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript is intronless :: BC069471.1 [ECO:0000345] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
ATGGCTTTGC CTTTTGCTTT ACTGATGGCC CTGGTGGTGC TCAGCTGCAA GTCAAGCTGC 
TCTCTGGACT GTGATCTGCC TCAGACCCAC AGCCTGGGTC ACAGGAGGAC CATGATGCTC
CTGGCACAAA TGAGGAGAAT CTCTCTTTTC TCCTGTCTGA AGGACAGACA TGACTTCAGA
TTTCCCCAGG AGGAGTTTGA TGGCAACCAG TTCCAGAAGG CTGAAGCCAT CTCTGTCCTC
CATGAGGTGA TTCAGCAGAC CTTCAACCTC TTCAGCACAA AGGACTCATC TGTTGCTTGG
GATGAGAGGC TTCTAGACAA ACTCTATACT GAACTTTACC AGCAGCTGAA TGACCTGGAA
GCCTGTGTGA TGCAGGAGGT GTGGGTGGGA GGGACTCCCC TGATGAATGA GGACTCCATC
CTGGCTGTGA GAAAATACTT CCAAAGAATC ACTCTCTACC TGACAGAGAA AAAGTACAGC
CCTTGTGCCT GGGAGGTTGT CAGAGCAGAA ATCATGAGAT CCTTCTCTTC ATCAAGAAAC
TTGCAAGAAA GGTTAAGGAG GAAGGAATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_066282.1
CDS1..570
Misc Feature(1)76..534(+)
Misc Feature(2)82..363(+)
Misc Feature(3)157..480(+)
Misc Feature(4)301..303(+)
Exon (1)1..570
Gene:IFNA6
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_021002
Organism Homo sapiens (human)
Definition Homo sapiens interferon, alpha 6 (IFNA6), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_021002

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
ATGGCTTTGC CTTTTGCTTT ACTGATGGCC CTGGTGGTGC TCAGCTGCAA GTCAAGCTGC 
TCTCTGGACT GTGATCTGCC TCAGACCCAC AGCCTGGGTC ACAGGAGGAC CATGATGCTC
CTGGCACAAA TGAGGAGAAT CTCTCTTTTC TCCTGTCTGA AGGACAGACA TGACTTCAGA
TTTCCCCAGG AGGAGTTTGA TGGCAACCAG TTCCAGAAGG CTGAAGCCAT CTCTGTCCTC
CATGAGGTGA TTCAGCAGAC CTTCAACCTC TTCAGCACAA AGGACTCATC TGTTGCTTGG
GATGAGAGGC TTCTAGACAA ACTCTATACT GAACTTTACC AGCAGCTGAA TGACCTGGAA
GCCTGTGTGA TGCAGGAGGT GTGGGTGGGA GGGACTCCCC TGATGAATGA GGACTCCATC
CTGGCTGTGA GAAAATACTT CCAAAGAATC ACTCTCTACC TGACAGAGAA AAAGTACAGC
CCTTGTGCCT GGGAGGTTGT CAGAGCAGAA ATCATGAGAT CCTTCTCTTC ATCAAGAAAC
TTGCAAGAAA GGTTAAGGAG GAAGGAATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

Associations of 9p21 variants with cutaneous malignant melanoma, nevi, and pigmentation phenotypes in melanoma-prone families with and without CDKN2A mutations
Fam. Cancer 9 (4), 625-633 (2010)
Yang XR, Liang X, Pfeiffer RM, Wheeler W, Maeder D, Burdette L, Yeager M, Chanock S, Tucker MA and Goldstein AM.


book

Dengue hemorrhagic fever is associated with polymorphisms in JAK1
Eur. J. Hum. Genet. 18 (11), 1221-1227 (2010)
Silva LK, Blanton RE, Parrado AR, Melo PS, Morato VG, Reis EA, Dias JP, Castro JM, Vasconcelos PF, Goddard KA, Barreto ML, Reis MG and Teixeira MG.


book

Interleukin-9 polymorphism in infants with respiratory syncytial virus infection: an opposite effect in boys and girls
Pediatr. Pulmonol. 45 (6), 608-613 (2010)
Schuurhof A, Bont L, Siezen CL, Hodemaekers H, van Houwelingen HC, Kimman TG, Hoebee B, Kimpen JL and Janssen R.


book

Large-scale candidate gene analysis of spontaneous clearance of hepatitis C virus
J. Infect. Dis. 201 (9), 1371-1380 (2010)
Mosbruger TL, Duggal P, Goedert JJ, Kirk GD, Hoots WK, Tobler LH, Busch M, Peters MG, Rosen HR, Thomas DL and Thio CL.


book

New genetic associations detected in a host response study to hepatitis B vaccine
Genes Immun. 11 (3), 232-238 (2010)
Davila S, Froeling FE, Tan A, Bonnard C, Boland GJ, Snippe H, Hibberd ML and Seielstad M.


book

Identification of nine interferon-alpha subtypes produced by Sendai virus-induced human peripheral blood leucocytes
Biochem. J. 329 (PT 2), 295-302 (1998)
Nyman TA, Tolo H, Parkkinen J and Kalkkinen N.


book

Alpha interferon suppresses the cyclin D3 and cdc25A genes, leading to a reversible G0-like arrest
Mol. Cell. Biol. 16 (7), 3934-3944 (1996)
Tiefenbrun N, Melamed D, Levy N, Resnitzky D, Hoffman I, Reed SI and Kimchi A.


book

Interferon activation of the transcription factor Stat91 involves dimerization through SH2-phosphotyrosyl peptide interactions
Cell 76 (5), 821-828 (1994)
Shuai K, Horvath CM, Huang LH, Qureshi SA, Cowburn D and Darnell JE Jr.


book

Mapping of the shortest region of overlap of deletions of the short arm of chromosome 9 associated with human neoplasia
Genomics 14 (2), 437-443 (1992)
Olopade OI, Bohlander SK, Pomykala H, Maltepe E, Van Melle E, Le Beau MM and Diaz MO.


book

Structural relationship of human interferon alpha genes and pseudogenes
J. Mol. Biol. 185 (2), 227-260 (1985)
Henco,K., Brosius,J., Fujisawa,A., Fujisawa,J.I., Haynes,J.R., Hochstadt,J., Kovacic,T., Pasek,M., Schambock,A., Schmid,J. et al.


 
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