The following IL2RB gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the IL2RB gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
||Documents for ORF clone product in dufault vector
||ORF Nucleotide Sequence (Length: 1656bp)
||pcDNA3.1+/C-(K)DYK or customized vector
||Document: User manual_GenEZ ORF Clone Products.pdf (pdf)
|Tag on pcDNA3.1+/C-(K)DYK
||C terminal DYKDDDDK tags
||Document: MSDS_GenEZ ORF Clone Products.pdf (pdf)
|ORF Insert Method
||CloneEZ® Seamless cloning technology
||Homo sapiens (human)
||interleukin-2 receptor subunit beta precursor
||REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from M26062.1, BC025691.1 and
On Jun 13, 2012 this sequence version replaced gi:23238195.
Summary: The interleukin 2 receptor, which is involved in T
cell-mediated immune responses, is present in 3 forms with respect
to ability to bind interleukin 2. The low affinity form is a
monomer of the alpha subunit and is not involved in signal
transduction. The intermediate affinity form consists of an
alpha/beta subunit heterodimer, while the high affinity form
consists of an alpha/beta/gamma subunit heterotrimer. Both the
intermediate and high affinity forms of the receptor are involved
in receptor-mediated endocytosis and transduction of mitogenic
signals from interleukin 2. The protein encoded by this gene
represents the beta subunit and is a type I membrane protein.
[provided by RefSeq, Jul 2008].
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
Transcript exon combination :: M26062.1, BC025691.1 [ECO:0000332]
RNAseq introns :: mixed/partial sample support
COMPLETENESS: complete on the 3' end.