Email to GenScript

IL2RB interleukin 2 receptor, beta [Homo sapiens (human)]

Gene Symbol IL2RB
Entrez Gene ID 3560
Full Name interleukin 2 receptor, beta
Synonyms CD122, IL15RB, P70-75
General protein information
Preferred Names
interleukin-2 receptor subunit beta
Names
interleukin-2 receptor subunit beta
p75
IL-2RB
CD122 antigen
IL-2R subunit beta
IL-2 receptor subunit beta
interleukin 15 receptor, beta
high affinity IL-2 receptor beta subunit
high affinity IL-2 receptor subunit beta
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

22

22q13.1

Summary The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

146710

Disorder Html:





The following IL2RB gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the IL2RB gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu15617 NM_000878 Homo sapiens interleukin 2 receptor, beta (IL2RB), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$265.3
$379

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu15617
Accession Version NM_000878.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1656bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product interleukin-2 receptor subunit beta precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from M26062.1, BC025691.1 and AA834613.1. On Jun 13, 2012 this sequence version replaced gi:23238195. Summary: The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M26062.1, BC025691.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
ATGGCGGCCC CTGCTCTGTC CTGGCGTCTG CCCCTCCTCA TCCTCCTCCT GCCCCTGGCT 
ACCTCTTGGG CATCTGCAGC GGTGAATGGC ACTTCCCAGT TCACATGCTT CTACAACTCG
AGAGCCAACA TCTCCTGTGT CTGGAGCCAA GATGGGGCTC TGCAGGACAC TTCCTGCCAA
GTCCATGCCT GGCCGGACAG ACGGCGGTGG AACCAAACCT GTGAGCTGCT CCCCGTGAGT
CAAGCATCCT GGGCCTGCAA CCTGATCCTC GGAGCCCCAG ATTCTCAGAA ACTGACCACA
GTTGACATCG TCACCCTGAG GGTGCTGTGC CGTGAGGGGG TGCGATGGAG GGTGATGGCC
ATCCAGGACT TCAAGCCCTT TGAGAACCTT CGCCTGATGG CCCCCATCTC CCTCCAAGTT
GTCCACGTGG AGACCCACAG ATGCAACATA AGCTGGGAAA TCTCCCAAGC CTCCCACTAC
TTTGAAAGAC ACCTGGAGTT CGAGGCCCGG ACGCTGTCCC CAGGCCACAC CTGGGAGGAG
GCCCCCCTGC TGACTCTCAA GCAGAAGCAG GAATGGATCT GCCTGGAGAC GCTCACCCCA
GACACCCAGT ATGAGTTTCA GGTGCGGGTC AAGCCTCTGC AAGGCGAGTT CACGACCTGG
AGCCCCTGGA GCCAGCCCCT GGCCTTCAGG ACAAAGCCTG CAGCCCTTGG GAAGGACACC
ATTCCGTGGC TCGGCCACCT CCTCGTGGGC CTCAGCGGGG CTTTTGGCTT CATCATCTTA
GTGTACTTGC TGATCAACTG CAGGAACACC GGGCCATGGC TGAAGAAGGT CCTGAAGTGT
AACACCCCAG ACCCCTCGAA GTTCTTTTCC CAGCTGAGCT CAGAGCATGG AGGAGACGTC
CAGAAGTGGC TCTCTTCGCC CTTCCCCTCA TCGTCCTTCA GCCCTGGCGG CCTGGCACCT
GAGATCTCGC CACTAGAAGT GCTGGAGAGG GACAAGGTGA CGCAGCTGCT CCTGCAGCAG
GACAAGGTGC CTGAGCCCGC ATCCTTAAGC AGCAACCACT CGCTGACCAG CTGCTTCACC
AACCAGGGTT ACTTCTTCTT CCACCTCCCG GATGCCTTGG AGATAGAGGC CTGCCAGGTG
TACTTTACTT ACGACCCCTA CTCAGAGGAA GACCCTGATG AGGGTGTGGC CGGGGCACCC
ACAGGGTCTT CCCCCCAACC CCTGCAGCCT CTGTCAGGGG AGGACGACGC CTACTGCACC
TTCCCCTCCA GGGATGACCT GCTGCTCTTC TCCCCCAGTC TCCTCGGTGG CCCCAGCCCC
CCAAGCACTG CCCCTGGGGG CAGTGGGGCC GGTGAAGAGA GGATGCCCCC TTCTTTGCAA
GAAAGAGTCC CCAGAGACTG GGACCCCCAG CCCCTGGGGC CTCCCACCCC AGGAGTCCCA
GACCTGGTGG ATTTTCAGCC ACCCCCTGAG CTGGTGCTGC GAGAGGCTGG GGAGGAGGTC
CCTGACGCTG GCCCCAGGGA GGGAGTCAGT TTCCCCTGGT CCAGGCCTCC TGGGCAGGGG
GAGTTCAGGG CCCTTAATGC TCGCCTGCCC CTGAACACTG ATGCCTACTT GTCCCTCCAA
GAACTCCAGG GTCAGGACCC AACTCACTTG GTGTAG
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_000869.1
CDS132..1787
Misc Feature(1)531..824(+)
Misc Feature(2)729..776(+)
Misc Feature(3)789..803(+)
Misc Feature(4)789..803(+)
Misc Feature(5)852..926(+)
Misc Feature(6)963..989(+)
Misc Feature(7)1221..1223(+)
Misc Feature(8)1272..1274(+)
Misc Feature(9)1281..1283(+)
Misc Feature(10)1290..1292(+)
Misc Feature(11)1383..1385(+)
Misc Feature(12)1737..1739(+)
Exon (1)1..98
Gene:IL2RB
Gene Synonym:
Exon (2)99..219
Gene:IL2RB
Gene Synonym:
Exon (3)220..334
Gene:IL2RB
Gene Synonym:
Exon (4)335..413
Gene:IL2RB
Gene Synonym:
Exon (5)414..519
Gene:IL2RB
Gene Synonym:
Exon (6)520..668
Gene:IL2RB
Gene Synonym:
Exon (7)669..834
Gene:IL2RB
Gene Synonym:
Exon (8)835..949
Gene:IL2RB
Gene Synonym:
Exon (9)950..1034
Gene:IL2RB
Gene Synonym:
Exon (10)1035..4045
Gene:IL2RB
Gene Synonym:
Translation
Position Chain Variation Link
30 30 g, t dbSNP:371187476
38 38 c, t dbSNP:775782851
49 49 c, t dbSNP:112662718
67 67 c, t dbSNP:759150911
68 68 a, g dbSNP:150921267
70 70 a, g dbSNP:544580076
71 71 c, t dbSNP:3218250
72 72 a, g dbSNP:772001377
75 75 a, g dbSNP:565349641
80 80 c, t dbSNP:540304329
81 81 a, g dbSNP:368382925
109 109 c, t dbSNP:768160154
111 111 c, t dbSNP:183183988
120 120 c, t dbSNP:775284056
127 127 a, t dbSNP:573820748
136 136 c, t dbSNP:769321719
137 137 a, g dbSNP:745709508
142 142 c, t dbSNP:542508078
145 145 c, g dbSNP:148235304
149 149 a, g dbSNP:781105134
156 156 c, t dbSNP:143132364
157 157 a, g dbSNP:147593802
159 159 c, g dbSNP:57770674
165 165 c, t dbSNP:758438266
176 176 c, t dbSNP:377485257
180 180 c, t dbSNP:550956957
181 181 c, t dbSNP:755168776
190 190 c, t dbSNP:538970680
195 195 c, t dbSNP:145316401
208 208 c, t dbSNP:761189356
211 211 c, t dbSNP:141522549
224 224 g, t dbSNP:772860858
229 229 a, g dbSNP:147889445
236 236 a, g dbSNP:747994966
244 244 a, t dbSNP:774508915
245 245 c, t dbSNP:768662521
251 251 a, g dbSNP:114542628
257 257 c, t dbSNP:148800183
259 259 a, g dbSNP:756309404
270 270 c, g dbSNP:746287644
277 277 a, g dbSNP:781374102
280 280 a, c dbSNP:757808344
284 284 c, t dbSNP:751954007
286 286 c, g dbSNP:764846722
294 294 a, c dbSNP:538933768
314 314 c, t dbSNP:753385492
315 315 c, t dbSNP:185863845
317 317 c, t dbSNP:374479635
325 325 c, t dbSNP:371340355
326 326 a, g, t dbSNP:150659506
333 333 c, t dbSNP:375594279
336 336 c, g, t dbSNP:117728347
338 338 a, g dbSNP:780762095
345 345 a, c dbSNP:756906160
347 347 a, t dbSNP:751391631
354 354 c, g dbSNP:763830083
356 356 c, g dbSNP:113714217
364 364 c, t dbSNP:762894023
365 365 c, t dbSNP:111730897
366 366 a, g dbSNP:149508414
379 379 c, t dbSNP:2228143
396 396 a, t dbSNP:776750362
398 398 c, t dbSNP:771097985
401 401 c, t dbSNP:760939018
402 402 a, g dbSNP:773733100
406 406 a, c dbSNP:183884204
412 412 a, g dbSNP:759693142
428 428 c, t dbSNP:117987928
440 440 c, t dbSNP:200052713
459 459 c, t dbSNP:758258445
462 462 c, t dbSNP:369774326
463 463 a, g dbSNP:137877148
467 467 a, g dbSNP:754913784
475 475 a, g dbSNP:375543770
477 477 c, t dbSNP:766430737
478 478 a, g dbSNP:760990294
479 479 g, t dbSNP:773498163
483 483 c, g dbSNP:767844744
487 487 c, t dbSNP:550638824
494 494 c, g dbSNP:532503786
496 496 a, g dbSNP:769078456
498 498 a, c, g dbSNP:776022568
500 500 a, c, t dbSNP:770365586
518 518 c, t dbSNP:746518875
519 519 a, c, t dbSNP:146185118
522 522 c, t dbSNP:781374953
525 525 -, c dbSNP:746806656
532 532 c, t dbSNP:201441730
537 537 a, c, t dbSNP:764222346
545 545 c, t dbSNP:763434888
558 558 c, g dbSNP:752982148
577 577 a, g dbSNP:765775857
590 590 a, c dbSNP:149258462
602 602 c, t dbSNP:371794346
604 604 c, t dbSNP:771510617
630 630 c, t dbSNP:200381499
633 633 a, g dbSNP:761376327
636 636 a, g dbSNP:774119548
639 639 c, t dbSNP:768177172
640 640 a, g dbSNP:749152355
643 643 c, t dbSNP:750566804
644 644 a, g dbSNP:138490007
647 647 a, g dbSNP:745746134
649 649 a, c dbSNP:368501031
651 651 c, g dbSNP:781429683
665 665 c, g dbSNP:757429668
666 666 a, g dbSNP:751581549
673 673 c, g dbSNP:558286731
675 675 a, c dbSNP:755401765
682 682 a, t dbSNP:754187933
689 689 c, g dbSNP:766917821
702 702 a, c, g dbSNP:541405891
708 708 a, g dbSNP:751108462
713 713 c, t dbSNP:369748788
721 721 c, t dbSNP:143330463
722 722 -, gc dbSNP:758275711
722 722 a, g dbSNP:762675060
730 730 c, g dbSNP:565954565
731 731 a, g dbSNP:554006847
734 734 a, c dbSNP:140822038
736 736 a, c dbSNP:759456562
737 737 c, g dbSNP:375725531
742 742 a, g dbSNP:776537544
755 755 a, g dbSNP:770932926
756 756 a, c, t dbSNP:773356308
757 757 a, g dbSNP:771977182
759 759 a, g dbSNP:748219773
765 765 c, t dbSNP:138141902
768 768 c, t dbSNP:755170506
777 777 a, g dbSNP:749689794
784 784 c, t dbSNP:780238707
785 785 a, g dbSNP:756664397
787 787 c, t dbSNP:750832111
794 794 c, t dbSNP:781721809
819 819 a, g dbSNP:147009331
835 835 c, t dbSNP:375780607
857 857 a, g dbSNP:752286646
863 863 c, t dbSNP:778519038
864 864 a, g dbSNP:754692430
873 873 -, ctc dbSNP:756244090
876 876 g, t dbSNP:147866253
878 878 a, g dbSNP:753366559
881 881 c, t dbSNP:228953
885 885 a, g dbSNP:760444455
887 887 c, t dbSNP:200064374
890 890 g, t dbSNP:767482253
906 906 -, atc dbSNP:750532739
906 906 a, g dbSNP:140720297
923 923 a, g dbSNP:774433459
926 926 a, c dbSNP:768662546
929 929 c, t dbSNP:763018682
938 938 c, t dbSNP:201360122
941 941 c, t dbSNP:115475423
942 942 a, g dbSNP:116250343
960 960 a, g dbSNP:755741228
963 963 c, t dbSNP:9610653
972 972 a, g, t dbSNP:369612891
983 983 c, t dbSNP:757103924
988 988 c, t dbSNP:751336614
1000 1000 a, c, g dbSNP:764062848
1001 1001 c, t dbSNP:758319587
1016 1016 g, t dbSNP:139692590
1021 1021 c, g dbSNP:765304134
1022 1022 a, t dbSNP:759682504
1024 1024 a, g dbSNP:777062765
1026 1026 a, g dbSNP:766692890
1029 1029 a, g dbSNP:761168524
1031 1031 a, c dbSNP:773680055
1049 1049 a, g dbSNP:751701712
1055 1055 c, t dbSNP:774987417
1060 1060 c, t dbSNP:769023487
1063 1063 c, t dbSNP:376447587
1064 1064 a, g dbSNP:371694691
1066 1066 c, t dbSNP:770592834
1072 1072 a, g dbSNP:746610945
1079 1079 c, t dbSNP:146858997
1080 1080 a, g dbSNP:143857582
1100 1100 a, g dbSNP:747884487
1115 1115 a, g dbSNP:140182148
1116 1116 c, g dbSNP:754837040
1128 1128 a, g, t dbSNP:780229147
1129 1129 a, t dbSNP:756418045
1132 1132 c, t dbSNP:146173891
1133 1133 a, g dbSNP:529360210
1142 1142 c, t dbSNP:762294864
1145 1145 a, g dbSNP:751841017
1149 1149 a, c dbSNP:141159874
1155 1155 a, g dbSNP:763401507
1157 1157 c, g dbSNP:776131925
1158 1158 g, t dbSNP:770365642
1166 1166 a, g dbSNP:374025450
1169 1169 c, g, t dbSNP:771604727
1170 1170 a, g dbSNP:532394331
1171 1171 c, t dbSNP:773974796
1174 1174 a, c dbSNP:768733522
1177 1177 c, t dbSNP:565218788
1178 1178 a, c dbSNP:749175608
1180 1180 a, g dbSNP:780285266
1185 1185 a, g dbSNP:756328118
1188 1188 c, t dbSNP:148621370
1190 1190 c, t dbSNP:143940767
1192 1192 c, g dbSNP:757382391
1193 1193 a, g dbSNP:751977291
1196 1196 g, t dbSNP:764308277
1205 1205 c, g dbSNP:758914433
1208 1208 c, t dbSNP:765594084
1214 1214 c, t dbSNP:753273353
1229 1229 c, t dbSNP:546895176
1230 1230 -, ttc dbSNP:757359708
1239 1239 c, t dbSNP:760230452
1240 1240 a, c, t dbSNP:148074427
1241 1241 a, g dbSNP:761319106
1254 1254 a, c, t dbSNP:561029890
1261 1261 c, g dbSNP:149497090
1271 1271 a, g dbSNP:775624588
1274 1274 c, t dbSNP:769830605
1283 1283 c, t dbSNP:146986731
1284 1284 a, c, g dbSNP:182482913
1288 1288 c, g, t dbSNP:142845071
1304 1304 a, c dbSNP:228942
1315 1315 a, g dbSNP:758824351
1320 1320 a, g dbSNP:577547909
1322 1322 c, t dbSNP:150175464
1323 1323 a, g dbSNP:188869923
1326 1326 a, g dbSNP:749968627
1329 1329 c, g dbSNP:766876638
1335 1335 a, g dbSNP:761527107
1336 1336 g, t dbSNP:773942173
1342 1342 c, t dbSNP:374625831
1344 1344 c, t dbSNP:762889259
1349 1349 a, g dbSNP:775393264
1360 1360 c, g dbSNP:769877535
1364 1364 c, g dbSNP:200663995
1371 1371 a, g dbSNP:776776861
1376 1376 c, t dbSNP:151048201
1377 1377 a, g dbSNP:747101668
1379 1379 c, t dbSNP:185969164
1380 1380 a, g dbSNP:768345015
1387 1387 g, t dbSNP:748540516
1388 1388 c, t dbSNP:779196758
1389 1389 a, t dbSNP:755518723
1398 1398 g, t dbSNP:754227771
1401 1401 a, g dbSNP:780605415
1404 1404 a, g dbSNP:756774235
1406 1406 g, t dbSNP:751057059
1413 1413 c, t dbSNP:763877949
1416 1416 c, g, t dbSNP:752554555
1419 1419 c, t dbSNP:536446375
1420 1420 c, t dbSNP:569375482
1423 1423 c, t dbSNP:550783162
1425 1425 c, t dbSNP:770883704
1427 1427 a, c, t dbSNP:143704470
1429 1429 g, t dbSNP:772301238
1432 1432 c, t dbSNP:748309368
1436 1436 c, g, t dbSNP:768964296
1437 1437 a, g dbSNP:760070428
1440 1440 a, g dbSNP:181177639
1442 1442 c, t dbSNP:780474008
1443 1443 c, t dbSNP:756610778
1446 1446 a, g dbSNP:751144068
1449 1449 a, c, t dbSNP:775132140
1452 1452 a, c, t dbSNP:764933753
1453 1453 c, t dbSNP:759302292
1455 1455 a, c dbSNP:753639868
1462 1462 a, c dbSNP:766261874
1463 1463 c, t dbSNP:375951025
1468 1468 g, t dbSNP:773290833
1470 1470 a, g dbSNP:767514858
1475 1475 g, t dbSNP:761873852
1477 1477 a, g dbSNP:774612864
1479 1479 a, g dbSNP:371167679
1481 1481 c, t dbSNP:749653661
1489 1489 a, t dbSNP:775883056
1490 1490 g, t dbSNP:199581476
1491 1491 a, g dbSNP:746313255
1497 1497 c, g dbSNP:546931798
1498 1498 a, c dbSNP:758040509
1499 1499 a, c dbSNP:528353830
1504 1504 c, t dbSNP:778475110
1509 1509 a, c dbSNP:754621422
1513 1513 a, g dbSNP:753600029
1517 1517 -, ag dbSNP:751807719
1520 1520 a, c dbSNP:766135944
1525 1525 c, g dbSNP:756047497
1533 1533 a, g dbSNP:750423328
1534 1534 a, t dbSNP:767425074
1535 1535 c, t dbSNP:35134562
1536 1536 c, t dbSNP:200339234
1538 1538 c, t dbSNP:764252942
1542 1542 c, t dbSNP:763184334
1544 1544 c, t dbSNP:188695948
1550 1550 g, t dbSNP:770262548
1558 1558 c, t dbSNP:201428524
1559 1559 c, g, t dbSNP:202199075
1562 1562 a, g dbSNP:747694750
1566 1566 a, g dbSNP:778441020
1567 1567 c, t dbSNP:568481178
1569 1569 a, c dbSNP:754597674
1570 1570 c, t dbSNP:748901771
1572 1572 g, t dbSNP:576077710
1581 1581 a, g dbSNP:577584390
1582 1582 a, g dbSNP:779563925
1593 1593 a, c dbSNP:755957552
1594 1594 c, t dbSNP:750196405
1599 1599 -, g dbSNP:764400971
1605 1605 g, t dbSNP:767482213
1607 1607 a, g dbSNP:369066989
1611 1611 a, c dbSNP:757144557
1612 1612 a, g dbSNP:751611989
1624 1624 -, a dbSNP:34283988
1626 1626 a, g dbSNP:764168940
1628 1628 c, g dbSNP:762939829
1632 1632 c, t dbSNP:753021407
1637 1637 a, c, t dbSNP:200168333
1644 1644 c, t dbSNP:777099904
1645 1645 c, t dbSNP:771591398
1657 1657 g, t dbSNP:761209228
1667 1667 a, c dbSNP:773735774
1678 1678 c, t dbSNP:200831371
1681 1681 c, t dbSNP:558884429
1683 1683 g, t dbSNP:779802723
1701 1701 a, g dbSNP:769404639
1713 1713 c, t dbSNP:377234631
1714 1714 a, g dbSNP:780914414
1720 1720 c, g dbSNP:757198038
1724 1724 c, g dbSNP:751582989
1761 1761 a, g dbSNP:777560629
1766 1766 a, g dbSNP:758554987
1770 1770 c, t dbSNP:573251262
1773 1773 a, c dbSNP:752689706
1783 1783 c, t dbSNP:147038391
1784 1784 a, g dbSNP:759786293
1789 1789 c, g dbSNP:754271259
1799 1799 a, g dbSNP:766780485
1806 1806 a, c dbSNP:760940391
1822 1822 c, g dbSNP:771888990
1827 1827 a, g dbSNP:773822329
1828 1828 c, g, t dbSNP:543241970
1829 1829 a, g dbSNP:774939961
1831 1831 c, t dbSNP:3218326
1832 1832 a, g dbSNP:745463802
1844 1844 a, g dbSNP:376035267
1864 1864 c, g dbSNP:538764608
1879 1879 c, t dbSNP:3218327
1914 1914 c, t dbSNP:538724059
1915 1915 a, g dbSNP:3218328
1930 1930 a, c dbSNP:184918997
1976 1976 c, t dbSNP:749145265
1979 1979 a, g dbSNP:535012800
1992 1992 c, t dbSNP:567604114
2019 2019 c, g dbSNP:549281127
2043 2043 c, t dbSNP:530758702
2044 2044 g, t dbSNP:781536083
2059 2059 c, t dbSNP:755295087
2062 2062 a, c, t dbSNP:192146486
2070 2070 a, g dbSNP:780198407
2087 2087 c, g dbSNP:76794334
2090 2090 c, t dbSNP:750963931
2127 2127 c, t dbSNP:532844221
2131 2131 g, t dbSNP:765532862
2139 2139 -, g dbSNP:34875471
2144 2144 c, t dbSNP:559022107
2149 2149 c, t dbSNP:540668132
2154 2154 c, g dbSNP:528844032
2159 2159 a, c dbSNP:189536875
2185 2185 -, cct dbSNP:569105857
2201 2201 c, g dbSNP:542924493
2202 2202 c, g dbSNP:228941
2231 2231 a, c dbSNP:3218329
2245 2245 a, g dbSNP:763646939
2250 2250 a, g dbSNP:374788096
2254 2254 c, t dbSNP:567514277
2257 2257 c, g dbSNP:545487206
2259 2259 a, c, t dbSNP:3218330
2261 2261 a, g dbSNP:774803579
2273 2273 a, g dbSNP:551022537
2276 2276 c, g dbSNP:771615675
2287 2287 a, g dbSNP:185417988
2299 2299 a, g dbSNP:192627099
2315 2315 c, t dbSNP:759000981
2322 2322 c, t dbSNP:3218331
2325 2325 c, t dbSNP:536909831
2332 2332 a, g dbSNP:569839053
2396 2396 c, t dbSNP:753430154
2402 2402 -, c dbSNP:767890904
2409 2409 a, g dbSNP:551335257
2410 2410 c, t dbSNP:774409608
2433 2433 a, t dbSNP:3218365
2438 2438 c, g dbSNP:41309804
2492 2492 g, t dbSNP:3218332
2499 2499 a, g dbSNP:749092330
2541 2541 c, t dbSNP:773201526
2603 2603 c, t dbSNP:228940
2617 2617 a, t dbSNP:3218366
2651 2651 c, t dbSNP:41309802
2675 2675 -, gg dbSNP:140647613
2677 2677 a, g dbSNP:55874649
2713 2713 g, t dbSNP:113775198
2718 2718 a, c dbSNP:531065205
2733 2733 c, t dbSNP:535882813
2734 2734 c, t dbSNP:769012213
2787 2787 a, g dbSNP:564003994
2791 2791 c, t dbSNP:560241980
2818 2818 a, g dbSNP:148887561
2873 2873 a, g dbSNP:545317540
2874 2874 -, c dbSNP:35536547
2895 2895 a, g dbSNP:228939
2899 2899 a, g dbSNP:370322848
2914 2914 a, t dbSNP:559912092
2925 2925 a, g dbSNP:763103157
2937 2937 c, t dbSNP:541506310
2954 2954 a, g dbSNP:745993014
2980 2980 a, c, t dbSNP:574095853
3034 3034 a, c dbSNP:555431373
3036 3036 c, g dbSNP:537453378
3065 3065 c, t dbSNP:576301488
3079 3079 a, c dbSNP:769874312
3116 3116 c, g dbSNP:145621853
3121 3121 c, t dbSNP:539277333
3144 3144 a, g dbSNP:367989504
3148 3148 a, c dbSNP:781379336
3158 3158 a, c dbSNP:228938
3181 3181 a, c dbSNP:554728242
3216 3216 a, g dbSNP:114845216
3233 3233 a, g dbSNP:149733695
3258 3258 c, t dbSNP:531326091
3274 3274 -, c dbSNP:112852512
3275 3275 a, c dbSNP:139628494
3317 3317 c, t dbSNP:552026799
3398 3398 a, c dbSNP:111460079
3405 3405 g, t dbSNP:755655607
3426 3426 g, t dbSNP:559948882
3462 3462 c, t dbSNP:541543040
3486 3486 c, t dbSNP:373988054
3487 3487 g, t dbSNP:562204591
3523 3523 g, t dbSNP:183295072
3559 3559 a, g dbSNP:576363750
3597 3597 a, g dbSNP:146413240
3622 3622 a, g dbSNP:777657559
3623 3623 a, c dbSNP:758294117
3632 3632 a, t dbSNP:3218367
3646 3646 c, g, t dbSNP:190679692
3650 3650 a, g dbSNP:139174446
3757 3757 a, g dbSNP:535266550
3776 3776 a, t dbSNP:778399721
3811 3811 g, t dbSNP:186213678
3836 3836 c, t dbSNP:549832196
3864 3864 g, t dbSNP:774074065
3867 3867 c, t dbSNP:15696
3875 3875 g, t dbSNP:766407624
3920 3920 c, t dbSNP:754709450
3926 3926 a, g dbSNP:3218333
3936 3936 c, t dbSNP:763001183
3937 3937 g, t dbSNP:566527036
3943 3943 a, g dbSNP:183158957
3955 3955 a, t dbSNP:553094546
3986 3986 a, g dbSNP:568229091
3989 3989 -, a dbSNP:532026807
3990 3990 a, c dbSNP:3218334
3998 3998 c, t dbSNP:191061260

Target ORF information:

RefSeq Version NM_000878
Organism Homo sapiens (human)
Definition Homo sapiens interleukin 2 receptor, beta (IL2RB), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_000878

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
ATGGCGGCCC CTGCTCTGTC CTGGCGTCTG CCCCTCCTCA TCCTCCTCCT GCCCCTGGCT 
ACCTCTTGGG CATCTGCAGC GGTGAATGGC ACTTCCCAGT TCACATGCTT CTACAACTCG
AGAGCCAACA TCTCCTGTGT CTGGAGCCAA GATGGGGCTC TGCAGGACAC TTCCTGCCAA
GTCCATGCCT GGCCGGACAG ACGGCGGTGG AACCAAACCT GTGAGCTGCT CCCCGTGAGT
CAAGCATCCT GGGCCTGCAA CCTGATCCTC GGAGCCCCAG ATTCTCAGAA ACTGACCACA
GTTGACATCG TCACCCTGAG GGTGCTGTGC CGTGAGGGGG TGCGATGGAG GGTGATGGCC
ATCCAGGACT TCAAGCCCTT TGAGAACCTT CGCCTGATGG CCCCCATCTC CCTCCAAGTT
GTCCACGTGG AGACCCACAG ATGCAACATA AGCTGGGAAA TCTCCCAAGC CTCCCACTAC
TTTGAAAGAC ACCTGGAGTT CGAGGCCCGG ACGCTGTCCC CAGGCCACAC CTGGGAGGAG
GCCCCCCTGC TGACTCTCAA GCAGAAGCAG GAATGGATCT GCCTGGAGAC GCTCACCCCA
GACACCCAGT ATGAGTTTCA GGTGCGGGTC AAGCCTCTGC AAGGCGAGTT CACGACCTGG
AGCCCCTGGA GCCAGCCCCT GGCCTTCAGG ACAAAGCCTG CAGCCCTTGG GAAGGACACC
ATTCCGTGGC TCGGCCACCT CCTCGTGGGC CTCAGCGGGG CTTTTGGCTT CATCATCTTA
GTGTACTTGC TGATCAACTG CAGGAACACC GGGCCATGGC TGAAGAAGGT CCTGAAGTGT
AACACCCCAG ACCCCTCGAA GTTCTTTTCC CAGCTGAGCT CAGAGCATGG AGGAGACGTC
CAGAAGTGGC TCTCTTCGCC CTTCCCCTCA TCGTCCTTCA GCCCTGGCGG CCTGGCACCT
GAGATCTCGC CACTAGAAGT GCTGGAGAGG GACAAGGTGA CGCAGCTGCT CCTGCAGCAG
GACAAGGTGC CTGAGCCCGC ATCCTTAAGC AGCAACCACT CGCTGACCAG CTGCTTCACC
AACCAGGGTT ACTTCTTCTT CCACCTCCCG GATGCCTTGG AGATAGAGGC CTGCCAGGTG
TACTTTACTT ACGACCCCTA CTCAGAGGAA GACCCTGATG AGGGTGTGGC CGGGGCACCC
ACAGGGTCTT CCCCCCAACC CCTGCAGCCT CTGTCAGGGG AGGACGACGC CTACTGCACC
TTCCCCTCCA GGGATGACCT GCTGCTCTTC TCCCCCAGTC TCCTCGGTGG CCCCAGCCCC
CCAAGCACTG CCCCTGGGGG CAGTGGGGCC GGTGAAGAGA GGATGCCCCC TTCTTTGCAA
GAAAGAGTCC CCAGAGACTG GGACCCCCAG CCCCTGGGGC CTCCCACCCC AGGAGTCCCA
GACCTGGTGG ATTTTCAGCC ACCCCCTGAG CTGGTGCTGC GAGAGGCTGG GGAGGAGGTC
CCTGACGCTG GCCCCAGGGA GGGAGTCAGT TTCCCCTGGT CCAGGCCTCC TGGGCAGGGG
GAGTTCAGGG CCCTTAATGC TCGCCTGCCC CTGAACACTG ATGCCTACTT GTCCCTCCAA
GAACTCCAGG GTCAGGACCC AACTCACTTG GTGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.