||ORF Nucleotide Sequence (Length: 1656bp)
||pcDNA3.1-C-(k)DYK or customized vector
|Tag on pcDNA3.1-C-(k)DYK
||C terminal DYKDDDDK tags
|ORF Insert Method
||CloneEZ® Seamless cloning technology
||Homo sapiens (human)
||interleukin-2 receptor subunit beta precursor
||REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from M26062.1, BC025691.1 and
On Jun 13, 2012 this sequence version replaced gi:23238195.
Summary: The interleukin 2 receptor, which is involved in T
cell-mediated immune responses, is present in 3 forms with respect
to ability to bind interleukin 2. The low affinity form is a
monomer of the alpha subunit and is not involved in signal
transduction. The intermediate affinity form consists of an
alpha/beta subunit heterodimer, while the high affinity form
consists of an alpha/beta/gamma subunit heterotrimer. Both the
intermediate and high affinity forms of the receptor are involved
in receptor-mediated endocytosis and transduction of mitogenic
signals from interleukin 2. The protein encoded by this gene
represents the beta subunit and is a type I membrane protein.
[provided by RefSeq, Jul 2008].
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
Transcript exon combination :: M26062.1, BC025691.1 [ECO:0000332]
RNAseq introns :: mixed/partial sample support
COMPLETENESS: complete on the 3' end.