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IL7R interleukin 7 receptor [Homo sapiens (human)]

Gene Symbol IL7R
Entrez Gene ID 3575
Full Name interleukin 7 receptor
Synonyms CD127, CDW127, IL-7R-alpha, IL7RA, ILRA
General protein information
Preferred Names
interleukin-7 receptor subunit alpha
Names
interleukin-7 receptor subunit alpha
IL-7RA
CD127 antigen
IL-7R subunit alpha
IL-7 receptor subunit alpha
interleukin 7 receptor alpha chain
interleukin 7 receptor isoform H5-6
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

5

5p13

Summary The protein encoded by this gene is a receptor for interleukine 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukine 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in the V(D)J recombination during lymphocyte development. This protein is also found to control the accessibility of the TCR gamma locus by STAT5 and histone acetylation. Knockout studies in mice suggested that blocking apoptosis is an essential function of this protein during differentiation and activation of T lymphocytes. The functional defects in this protein may be associated with the pathogenesis of the severe combined immunodeficiency (SCID). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2014]. lac of sum
Disorder MIM:

146661

Disorder Html: Severe combined immunodeficiency, T-cell negative, B-cell/natural





The following IL7R gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the IL7R gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu58399 XM_011514037 PREDICTED: Homo sapiens interleukin 7 receptor (IL7R), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $199
OHu39321 XM_005248299 PREDICTED: Homo sapiens interleukin 7 receptor (IL7R), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $199
OHu39322 XM_005248300 PREDICTED: Homo sapiens interleukin 7 receptor (IL7R), transcript variant X3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $199
OHu24651 NM_002185 Homo sapiens interleukin 7 receptor (IL7R), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$319

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu58399
Accession Version XM_011514037.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 807bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector Document: User manual_GenEZ ORF Clone Products.pdf (pdf)
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags Document: MSDS_GenEZ ORF Clone Products.pdf (pdf)
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product interleukin-7 receptor subunit alpha isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_006576.17) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGACAATTC TAGGTACAAC TTTTGGCATG GTTTTTTCTT TACTTCAAGT CGTTTCTGGA 
GAAAGTGGCT ATGCTCAAAA TGGAGACTTG GAAGATGCAG AACTGGATGA CTACTCATTC
TCATGCTATA GCCAGTTGGA AGTGAATGGA TCGCAGCACT CACTGACCTG TGCTTTTGAG
GACCCAGATG TCAACATCAC CAATCTGGAA TTTGAAATAT GTGGGGCCCT CGTGGAGGTA
AAGTGCCTGA ATTTCAGGAA ACTACAAGAG ATATATTTCA TCGAGACAAA GAAATTCTTA
CTGATTGGAA AGAGCAATAT ATGTGTGAAG GTTGGAGAAA AGAGTCTAAC CTGCAAAAAA
ATAGACCTAA CCACTATAGT TAAACCTGAG GCTCCTTTTG ACCTGAGTGT CGTCTATCGG
GAAGGAGCCA ATGACTTTGT GGTGACATTT AATACATCAC ACTTGCAAAA GAAGTATGTA
AAAGTTTTAA TGCACGATGT AGCTTACCGC CAGGAAAAGG ATGAAAACAA ATGGACGCAT
GTGAATTTAT CCAGCACAAA GCTGACACTC CTGCAGAGAA AGCTCCAACC GGCAGCAATG
TATGAGATTA AAGTTCGATC CATCCCTGAT CACTATTTTA AAGGCTTCTG GAGTGAATGG
AGTCCAAGTT ATTACTTCAG AACTCCAGAG ATCAATAATA GCTCAGGGGA GATGGATCCT
ATCTTACTAA CCATCAGCAT TTTGAGTTTT TTCTCTGTCG CTCTGTTGGT CATCTTGGCC
TGTGTGTTAT GGAAAAAAAA GGATTAA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqXP_011512339.1
CDS89..895
Misc Feature(1)593..772(+)
Misc Feature(2)677..736(+)
Misc Feature(3)737..751(+)
Translation
Position Chain Variation Link
5 5 c, t dbSNP:200523830
50 50 c, t dbSNP:201511279
60 60 a, g dbSNP:200169985
64 64 -, ct dbSNP:760977768
65 65 -, ctct dbSNP:764329514
65 65 -, ct dbSNP:775874510
67 67 a, c dbSNP:543865837
72 72 c, t dbSNP:200201139
73 73 c, g, t dbSNP:369139531
77 77 a, c, g dbSNP:200964795
78 78 a, t dbSNP:747999593
81 81 c, g dbSNP:758373857
85 85 c, g dbSNP:202196214
90 90 g, t dbSNP:200076125
105 105 c, t dbSNP:771047572
114 114 a, c, g dbSNP:776642878
115 115 c, t dbSNP:770050857
116 116 a, g dbSNP:145097494
120 120 c, t dbSNP:539820821
139 139 a, c, t dbSNP:138981776
148 148 a, t dbSNP:780995324
156 156 c, g dbSNP:760033705
164 164 c, t dbSNP:202007062
169 169 a, t dbSNP:753451294
175 175 c, t dbSNP:370292681
185 185 a, g dbSNP:140673282
191 191 a, c dbSNP:752402991
192 192 a, t dbSNP:35967524
199 199 c, t dbSNP:763937095
201 201 a, t dbSNP:751358220
216 216 a, g dbSNP:373694709
220 220 a, c, t dbSNP:11567704
223 223 g, t dbSNP:200464578
237 237 g, t dbSNP:202083738
240 240 c, g, t dbSNP:138482569
241 241 a, g dbSNP:149235072
244 244 g, t dbSNP:768814999
245 245 c, t dbSNP:779308643
253 253 a, g dbSNP:748495760
256 256 c, t dbSNP:267600609
262 262 -, t dbSNP:765287425
266 266 a, g dbSNP:772586152
277 277 g, t dbSNP:773872375
285 285 c, t dbSNP:1494558
296 296 a, g dbSNP:769426499
299 299 g, t dbSNP:775198948
300 300 a, c, t dbSNP:147423300
302 302 c, g dbSNP:148001159
315 315 c, t dbSNP:755030275
318 318 -, t dbSNP:766399441
320 320 a, g, t dbSNP:200687605
325 325 g, t dbSNP:552630274
327 327 c, t dbSNP:200475138
331 331 a, g dbSNP:747417170
333 333 g, t dbSNP:757797163
334 334 a, c dbSNP:201767916
353 353 c, t dbSNP:141698985
368 368 -, atatatttca dbSNP:193922640
370 370 c, t dbSNP:778067695
371 371 a, g dbSNP:191585195
378 378 a, c, g dbSNP:773973629
387 387 -, tac dbSNP:751425932
388 388 a, t dbSNP:771757728
389 389 c, t dbSNP:772953676
394 394 a, c, t dbSNP:200241281
395 395 a, g dbSNP:201106853
396 396 c, g dbSNP:776441054
397 397 a, g dbSNP:759585748
401 401 a, c dbSNP:199742437
402 402 a, g dbSNP:150051812
403 403 c, t dbSNP:201058754
407 407 a, g dbSNP:764440449
411 411 a, g dbSNP:751922549
413 413 a, g dbSNP:757709286
414 414 c, t dbSNP:781675111
420 420 c, g, t dbSNP:548638151
421 421 c, t dbSNP:199641706
423 423 g, t dbSNP:778262602
424 424 a, g dbSNP:200817423
427 427 a, c dbSNP:11567735
428 428 a, g dbSNP:771667604
430 430 c, g dbSNP:777419876
431 431 a, g dbSNP:746743911
432 432 -, tcta dbSNP:754784201
432 432 c, g dbSNP:537367054
441 441 a, g dbSNP:193922641
442 442 -, a dbSNP:781000678
446 446 a, g dbSNP:200506624
447 447 a, t dbSNP:201710684
451 451 a, c dbSNP:769810965
454 454 a, c dbSNP:140473900
461 461 a, g dbSNP:145407742
464 464 a, c, g dbSNP:201207454
466 466 a, g dbSNP:762188432
468 468 g, t dbSNP:751109965
473 473 c, t dbSNP:756821231
474 474 c, t dbSNP:780917994
479 479 c, g dbSNP:745590108
482 482 c, t dbSNP:104893894
490 490 c, t dbSNP:780061831
492 492 g, t dbSNP:199779006
493 493 c, g dbSNP:768760071
495 495 a, g dbSNP:201012821
499 499 c, t dbSNP:545307253
500 500 a, g dbSNP:1494555
503 503 g, t dbSNP:772130250
506 506 c, t dbSNP:773491081
507 507 a, g dbSNP:200373233
512 512 a, g dbSNP:200772681
515 515 a, g dbSNP:372676633
521 521 a, g dbSNP:201790329
526 526 a, t dbSNP:587778403
527 527 -, g dbSNP:747698244
527 527 g, t dbSNP:760005945
528 528 c, t dbSNP:765765854
529 529 a, g dbSNP:750985822
530 530 c, g dbSNP:200332345
531 531 g, t dbSNP:767009659
534 534 c, t dbSNP:201940568
544 544 a, c, g dbSNP:112805866
548 548 c, t dbSNP:199727195
550 550 a, c dbSNP:749131336
554 554 c, t dbSNP:139221577
556 556 a, g dbSNP:112368558
564 564 a, t dbSNP:779013920
565 565 c, t dbSNP:748111926
567 567 -, t dbSNP:755779539
569 569 a, g dbSNP:200233367
578 578 a, t dbSNP:772191954
579 579 c, t dbSNP:771957502
582 582 a, c dbSNP:747236451
583 583 c, g, t dbSNP:2228141
584 584 a, g dbSNP:776941426
589 589 a, t dbSNP:199697302
591 591 c, t dbSNP:759917852
596 596 c, t dbSNP:145210284
597 597 a, g, t dbSNP:149161098
600 600 a, c dbSNP:531875566
603 603 a, g dbSNP:199654814
605 605 a, c dbSNP:749945425
607 607 a, g dbSNP:143661008
608 608 a, g dbSNP:375672744
616 616 a, c dbSNP:149833809
621 621 a, g dbSNP:753635194
622 622 a, g dbSNP:754827305
623 623 a, g dbSNP:778642997
624 624 a, c, t dbSNP:200751605
625 625 a, g dbSNP:758320927
626 626 c, t dbSNP:780435478
627 627 a, c dbSNP:193922642
628 628 c, t dbSNP:201040470
629 629 a, g dbSNP:62351970
630 630 c, t dbSNP:774732191
640 640 c, g, t dbSNP:748733640
647 647 a, g dbSNP:776330345
649 649 a, g, t dbSNP:11567764
658 658 c, g dbSNP:200528373
660 660 -, g dbSNP:777217507
661 661 g, t dbSNP:775310578
673 673 c, t dbSNP:762673467
678 678 c, t dbSNP:587778404
679 679 a, g dbSNP:201431556
682 682 a, c dbSNP:191457074
684 684 c, t dbSNP:767559651
687 687 a, t dbSNP:750537570
688 688 a, g dbSNP:754172661
690 690 a, g dbSNP:145810271
691 691 c, t dbSNP:200388101
704 704 cg, ta dbSNP:193922643
704 704 c, t dbSNP:201559094
705 705 a, g, t dbSNP:193922644
706 706 a, g dbSNP:755300062
708 708 c, g dbSNP:779479151
713 713 c, t dbSNP:748643880
717 717 a, t dbSNP:757795302
718 718 a, t dbSNP:772747002
723 723 a, g dbSNP:577344998
724 724 g, t dbSNP:786205572
732 732 g, t dbSNP:193922645
739 739 a, g dbSNP:104893893
741 741 a, g dbSNP:374232919
750 750 g, t dbSNP:587778405
754 754 a, c dbSNP:769433714
768 768 a, g dbSNP:148165103
770 770 a, c dbSNP:762736419
771 771 c, t dbSNP:201412341
773 773 c, t dbSNP:774177784
780 780 c, t dbSNP:761704139
783 783 a, g dbSNP:199714011
787 787 c, t dbSNP:566889429
789 789 c, g dbSNP:200894429
790 790 a, c dbSNP:201897242
792 792 c, t dbSNP:766555082
793 793 a, c dbSNP:753994938
795 795 a, g dbSNP:201084372
797 797 a, g dbSNP:372056746
799 799 a, g dbSNP:778351803
809 809 a, g dbSNP:141111406
814 814 a, c dbSNP:751999018
819 819 c, t dbSNP:6897932
825 825 g, t dbSNP:779397627
832 832 c, g dbSNP:200086692
835 835 -, t dbSNP:748801798
847 847 c, t dbSNP:201268331
848 848 a, c, g, t dbSNP:137868226
853 853 a, g dbSNP:143438470
859 859 c, t dbSNP:760499889
860 860 a, g, t dbSNP:200150755
861 861 c, t dbSNP:549460344
863 863 g, t dbSNP:559933153
866 866 a, g dbSNP:147153824
879 879 a, g dbSNP:752967041
883 883 a, g dbSNP:548783574
887 887 a, c dbSNP:764528268
896 896 a, g dbSNP:199814261
900 900 a, g dbSNP:773614197
902 902 c, t dbSNP:200468194
903 903 a, g dbSNP:369971728
920 920 a, c, t dbSNP:766895607
921 921 a, g dbSNP:201449880
934 934 c, t dbSNP:373309714
950 950 c, t dbSNP:375706394
964 964 -, agtg dbSNP:747377117
966 966 -, tgagtgtt dbSNP:768950875

Target ORF information:

RefSeq Version XM_011514037
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens interleukin 7 receptor (IL7R), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011514037

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGACAATTC TAGGTACAAC TTTTGGCATG GTTTTTTCTT TACTTCAAGT CGTTTCTGGA 
GAAAGTGGCT ATGCTCAAAA TGGAGACTTG GAAGATGCAG AACTGGATGA CTACTCATTC
TCATGCTATA GCCAGTTGGA AGTGAATGGA TCGCAGCACT CACTGACCTG TGCTTTTGAG
GACCCAGATG TCAACATCAC CAATCTGGAA TTTGAAATAT GTGGGGCCCT CGTGGAGGTA
AAGTGCCTGA ATTTCAGGAA ACTACAAGAG ATATATTTCA TCGAGACAAA GAAATTCTTA
CTGATTGGAA AGAGCAATAT ATGTGTGAAG GTTGGAGAAA AGAGTCTAAC CTGCAAAAAA
ATAGACCTAA CCACTATAGT TAAACCTGAG GCTCCTTTTG ACCTGAGTGT CGTCTATCGG
GAAGGAGCCA ATGACTTTGT GGTGACATTT AATACATCAC ACTTGCAAAA GAAGTATGTA
AAAGTTTTAA TGCACGATGT AGCTTACCGC CAGGAAAAGG ATGAAAACAA ATGGACGCAT
GTGAATTTAT CCAGCACAAA GCTGACACTC CTGCAGAGAA AGCTCCAACC GGCAGCAATG
TATGAGATTA AAGTTCGATC CATCCCTGAT CACTATTTTA AAGGCTTCTG GAGTGAATGG
AGTCCAAGTT ATTACTTCAG AACTCCAGAG ATCAATAATA GCTCAGGGGA GATGGATCCT
ATCTTACTAA CCATCAGCAT TTTGAGTTTT TTCTCTGTCG CTCTGTTGGT CATCTTGGCC
TGTGTGTTAT GGAAAAAAAA GGATTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu39321
Accession Version XM_005248299.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 789bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector Document: User manual_GenEZ ORF Clone Products.pdf (pdf)
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags Document: MSDS_GenEZ ORF Clone Products.pdf (pdf)
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product interleukin-7 receptor subunit alpha isoform X2
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_006576.17) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 3, 2014 this sequence version replaced gi:530378800. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGACAATTC TAGGTACAAC TTTTGGCATG GTTTTTTCTT TACTTCAAGT CGTTTCTGGA 
GAAAGTGGCT ATGCTCAAAA TGGAGACTTG GAAGATGCAG AACTGGATGA CTACTCATTC
TCATGCTATA GCCAGTTGGA AGTGAATGGA TCGCAGCACT CACTGACCTG TGCTTTTGAG
GACCCAGATG TCAACATCAC CAATCTGGAA TTTGAAATAT GTGGGGCCCT CGTGGAGGTA
AAGTGCCTGA ATTTCAGGAA ACTACAAGAG ATATATTTCA TCGAGACAAA GAAATTCTTA
CTGATTGGAA AGAGCAATAT ATGTGTGAAG GTTGGAGAAA AGAGTCTAAC CTGCAAAAAA
ATAGACCTAA CCACTATAGT TAAACCTGAG GCTCCTTTTG ACCTGAGTGT CGTCTATCGG
GAAGGAGCCA ATGACTTTGT GGTGACATTT AATACATCAC ACTTGCAAAA GAAGTATGTA
AAAGTTTTAA TGCACGATGT AGCTTACCGC CAGGAAAAGG ATGAAAACAA ATGGACGCAT
GTGAATTTAT CCAGCACAAA GCTGACACTC CTGCAGAGAA AGCTCCAACC GGCAGCAATG
TATGAGATTA AAGTTCGATC CATCCCTGAT CACTATTTTA AAGGCTTCTG GAGTGAATGG
AGTCCAAGTT ATTACTTCAG AACTCCAGAG ATCAATAATA GCTCAGGATT AAGCCTATCG
TATGGCCCAG TCTCCCCGAT CATAAGAAGA CTCTGGAACA TCTTTGTAAG AAACCAAGAA
AAAATTTAA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqXP_005248356.1
CDS89..877
Misc Feature(1)593..772(+)
Misc Feature(2)677..736(+)
Misc Feature(3)737..751(+)
Translation
Position Chain Variation Link
5 5 c, t dbSNP:200523830
50 50 c, t dbSNP:201511279
60 60 a, g dbSNP:200169985
64 64 -, ct dbSNP:760977768
65 65 -, ctct dbSNP:764329514
65 65 -, ct dbSNP:775874510
67 67 a, c dbSNP:543865837
72 72 c, t dbSNP:200201139
73 73 c, g, t dbSNP:369139531
77 77 a, c, g dbSNP:200964795
78 78 a, t dbSNP:747999593
81 81 c, g dbSNP:758373857
85 85 c, g dbSNP:202196214
90 90 g, t dbSNP:200076125
105 105 c, t dbSNP:771047572
114 114 a, c, g dbSNP:776642878
115 115 c, t dbSNP:770050857
116 116 a, g dbSNP:145097494
120 120 c, t dbSNP:539820821
139 139 a, c, t dbSNP:138981776
148 148 a, t dbSNP:780995324
156 156 c, g dbSNP:760033705
164 164 c, t dbSNP:202007062
169 169 a, t dbSNP:753451294
175 175 c, t dbSNP:370292681
185 185 a, g dbSNP:140673282
191 191 a, c dbSNP:752402991
192 192 a, t dbSNP:35967524
199 199 c, t dbSNP:763937095
201 201 a, t dbSNP:751358220
216 216 a, g dbSNP:373694709
220 220 a, c, t dbSNP:11567704
223 223 g, t dbSNP:200464578
237 237 g, t dbSNP:202083738
240 240 c, g, t dbSNP:138482569
241 241 a, g dbSNP:149235072
244 244 g, t dbSNP:768814999
245 245 c, t dbSNP:779308643
253 253 a, g dbSNP:748495760
256 256 c, t dbSNP:267600609
262 262 -, t dbSNP:765287425
266 266 a, g dbSNP:772586152
277 277 g, t dbSNP:773872375
285 285 c, t dbSNP:1494558
296 296 a, g dbSNP:769426499
299 299 g, t dbSNP:775198948
300 300 a, c, t dbSNP:147423300
302 302 c, g dbSNP:148001159
315 315 c, t dbSNP:755030275
318 318 -, t dbSNP:766399441
320 320 a, g, t dbSNP:200687605
325 325 g, t dbSNP:552630274
327 327 c, t dbSNP:200475138
331 331 a, g dbSNP:747417170
333 333 g, t dbSNP:757797163
334 334 a, c dbSNP:201767916
353 353 c, t dbSNP:141698985
368 368 -, atatatttca dbSNP:193922640
370 370 c, t dbSNP:778067695
371 371 a, g dbSNP:191585195
378 378 a, c, g dbSNP:773973629
387 387 -, tac dbSNP:751425932
388 388 a, t dbSNP:771757728
389 389 c, t dbSNP:772953676
394 394 a, c, t dbSNP:200241281
395 395 a, g dbSNP:201106853
396 396 c, g dbSNP:776441054
397 397 a, g dbSNP:759585748
401 401 a, c dbSNP:199742437
402 402 a, g dbSNP:150051812
403 403 c, t dbSNP:201058754
407 407 a, g dbSNP:764440449
411 411 a, g dbSNP:751922549
413 413 a, g dbSNP:757709286
414 414 c, t dbSNP:781675111
420 420 c, g, t dbSNP:548638151
421 421 c, t dbSNP:199641706
423 423 g, t dbSNP:778262602
424 424 a, g dbSNP:200817423
427 427 a, c dbSNP:11567735
428 428 a, g dbSNP:771667604
430 430 c, g dbSNP:777419876
431 431 a, g dbSNP:746743911
432 432 -, tcta dbSNP:754784201
432 432 c, g dbSNP:537367054
441 441 a, g dbSNP:193922641
442 442 -, a dbSNP:781000678
446 446 a, g dbSNP:200506624
447 447 a, t dbSNP:201710684
451 451 a, c dbSNP:769810965
454 454 a, c dbSNP:140473900
461 461 a, g dbSNP:145407742
464 464 a, c, g dbSNP:201207454
466 466 a, g dbSNP:762188432
468 468 g, t dbSNP:751109965
473 473 c, t dbSNP:756821231
474 474 c, t dbSNP:780917994
479 479 c, g dbSNP:745590108
482 482 c, t dbSNP:104893894
490 490 c, t dbSNP:780061831
492 492 g, t dbSNP:199779006
493 493 c, g dbSNP:768760071
495 495 a, g dbSNP:201012821
499 499 c, t dbSNP:545307253
500 500 a, g dbSNP:1494555
503 503 g, t dbSNP:772130250
506 506 c, t dbSNP:773491081
507 507 a, g dbSNP:200373233
512 512 a, g dbSNP:200772681
515 515 a, g dbSNP:372676633
521 521 a, g dbSNP:201790329
526 526 a, t dbSNP:587778403
527 527 -, g dbSNP:747698244
527 527 g, t dbSNP:760005945
528 528 c, t dbSNP:765765854
529 529 a, g dbSNP:750985822
530 530 c, g dbSNP:200332345
531 531 g, t dbSNP:767009659
534 534 c, t dbSNP:201940568
544 544 a, c, g dbSNP:112805866
548 548 c, t dbSNP:199727195
550 550 a, c dbSNP:749131336
554 554 c, t dbSNP:139221577
556 556 a, g dbSNP:112368558
564 564 a, t dbSNP:779013920
565 565 c, t dbSNP:748111926
567 567 -, t dbSNP:755779539
569 569 a, g dbSNP:200233367
578 578 a, t dbSNP:772191954
579 579 c, t dbSNP:771957502
582 582 a, c dbSNP:747236451
583 583 c, g, t dbSNP:2228141
584 584 a, g dbSNP:776941426
589 589 a, t dbSNP:199697302
591 591 c, t dbSNP:759917852
596 596 c, t dbSNP:145210284
597 597 a, g, t dbSNP:149161098
600 600 a, c dbSNP:531875566
603 603 a, g dbSNP:199654814
605 605 a, c dbSNP:749945425
607 607 a, g dbSNP:143661008
608 608 a, g dbSNP:375672744
616 616 a, c dbSNP:149833809
621 621 a, g dbSNP:753635194
622 622 a, g dbSNP:754827305
623 623 a, g dbSNP:778642997
624 624 a, c, t dbSNP:200751605
625 625 a, g dbSNP:758320927
626 626 c, t dbSNP:780435478
627 627 a, c dbSNP:193922642
628 628 c, t dbSNP:201040470
629 629 a, g dbSNP:62351970
630 630 c, t dbSNP:774732191
640 640 c, g, t dbSNP:748733640
647 647 a, g dbSNP:776330345
649 649 a, g, t dbSNP:11567764
658 658 c, g dbSNP:200528373
660 660 -, g dbSNP:777217507
661 661 g, t dbSNP:775310578
673 673 c, t dbSNP:762673467
678 678 c, t dbSNP:587778404
679 679 a, g dbSNP:201431556
682 682 a, c dbSNP:191457074
684 684 c, t dbSNP:767559651
687 687 a, t dbSNP:750537570
688 688 a, g dbSNP:754172661
690 690 a, g dbSNP:145810271
691 691 c, t dbSNP:200388101
704 704 cg, ta dbSNP:193922643
704 704 c, t dbSNP:201559094
705 705 a, g, t dbSNP:193922644
706 706 a, g dbSNP:755300062
708 708 c, g dbSNP:779479151
713 713 c, t dbSNP:748643880
717 717 a, t dbSNP:757795302
718 718 a, t dbSNP:772747002
723 723 a, g dbSNP:577344998
724 724 g, t dbSNP:786205572
732 732 g, t dbSNP:193922645
739 739 a, g dbSNP:104893893
741 741 a, g dbSNP:374232919
750 750 g, t dbSNP:587778405
754 754 a, c dbSNP:769433714
768 768 a, g dbSNP:148165103
770 770 a, c dbSNP:762736419
771 771 c, t dbSNP:201412341
773 773 c, t dbSNP:774177784
780 780 c, t dbSNP:761704139
783 783 a, g dbSNP:199714011
787 787 c, t dbSNP:566889429
789 789 c, g dbSNP:200894429
790 790 a, c dbSNP:201897242
792 792 c, t dbSNP:766555082
793 793 a, c dbSNP:753994938
801 801 a, g dbSNP:199814261
805 805 a, g dbSNP:773614197
807 807 c, t dbSNP:200468194
808 808 a, g dbSNP:369971728
825 825 a, c, t dbSNP:766895607
826 826 a, g dbSNP:201449880
839 839 c, t dbSNP:373309714
855 855 c, t dbSNP:375706394
869 869 -, agtg dbSNP:747377117
876 876 a, c dbSNP:193922647
879 879 -, t dbSNP:786205646
892 892 -, cctga dbSNP:763041846
898 898 a, c, g dbSNP:771361407
902 902 c, g, t dbSNP:200107390
909 909 c, t dbSNP:200889239
910 910 a, t dbSNP:748055663
913 913 a, c dbSNP:751073911
933 933 c, t dbSNP:761483945
934 934 a, g dbSNP:202060571
937 937 c, g dbSNP:767298556
944 944 a, c, g dbSNP:755809849
946 946 a, g dbSNP:200521932
951 951 a, c, t dbSNP:201275186
952 952 g, t dbSNP:202226690
953 953 g, t dbSNP:140979277
959 959 g, t dbSNP:754918897
966 966 a, g dbSNP:779019330
972 972 c, t dbSNP:370440024
974 974 c, g, t dbSNP:536561203
975 975 a, g dbSNP:200211847
980 980 c, t dbSNP:747299332
984 984 a, c, g dbSNP:201093124
994 994 a, g dbSNP:777033414
997 997 c, t dbSNP:199735993
1001 1001 a, g dbSNP:770237630
1005 1005 a, g dbSNP:773859083
1011 1011 g, t dbSNP:761241127
1012 1012 c, t dbSNP:767208665
1014 1014 c, g, t dbSNP:138731184
1015 1015 g, t dbSNP:766254348
1016 1016 a, g dbSNP:753614229
1019 1019 a, g dbSNP:754897111
1020 1020 a, g dbSNP:201058934
1029 1029 c, g dbSNP:765101557
1036 1036 a, g dbSNP:752755761
1037 1037 a, c, g dbSNP:41270321
1040 1040 a, c, g, t dbSNP:200927791
1042 1042 c, t dbSNP:111803690
1051 1051 a, g dbSNP:770274946
1056 1056 a, g dbSNP:775861133
1057 1057 a, g dbSNP:749870381

Target ORF information:

RefSeq Version XM_005248299
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens interleukin 7 receptor (IL7R), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_005248299

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGACAATTC TAGGTACAAC TTTTGGCATG GTTTTTTCTT TACTTCAAGT CGTTTCTGGA 
GAAAGTGGCT ATGCTCAAAA TGGAGACTTG GAAGATGCAG AACTGGATGA CTACTCATTC
TCATGCTATA GCCAGTTGGA AGTGAATGGA TCGCAGCACT CACTGACCTG TGCTTTTGAG
GACCCAGATG TCAACATCAC CAATCTGGAA TTTGAAATAT GTGGGGCCCT CGTGGAGGTA
AAGTGCCTGA ATTTCAGGAA ACTACAAGAG ATATATTTCA TCGAGACAAA GAAATTCTTA
CTGATTGGAA AGAGCAATAT ATGTGTGAAG GTTGGAGAAA AGAGTCTAAC CTGCAAAAAA
ATAGACCTAA CCACTATAGT TAAACCTGAG GCTCCTTTTG ACCTGAGTGT CGTCTATCGG
GAAGGAGCCA ATGACTTTGT GGTGACATTT AATACATCAC ACTTGCAAAA GAAGTATGTA
AAAGTTTTAA TGCACGATGT AGCTTACCGC CAGGAAAAGG ATGAAAACAA ATGGACGCAT
GTGAATTTAT CCAGCACAAA GCTGACACTC CTGCAGAGAA AGCTCCAACC GGCAGCAATG
TATGAGATTA AAGTTCGATC CATCCCTGAT CACTATTTTA AAGGCTTCTG GAGTGAATGG
AGTCCAAGTT ATTACTTCAG AACTCCAGAG ATCAATAATA GCTCAGGATT AAGCCTATCG
TATGGCCCAG TCTCCCCGAT CATAAGAAGA CTCTGGAACA TCTTTGTAAG AAACCAAGAA
AAAATTTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu39322
Accession Version XM_005248300.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 786bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector Document: User manual_GenEZ ORF Clone Products.pdf (pdf)
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags Document: MSDS_GenEZ ORF Clone Products.pdf (pdf)
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product interleukin-7 receptor subunit alpha isoform X3
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_006576.17) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGACAATTC TAGGTACAAC TTTTGGCATG GTTTTTTCTT TACTTCAAGT CGTTTCTGGA 
GAAAGTGGCT ATGCTCAAAA TGGAGACTTG GAAGATGCAG AACTGGATGA CTACTCATTC
TCATGCTATA GCCAGTTGGA AGTGAATGGA TCGCAGCACT CACTGACCTG TGCTTTTGAG
GACCCAGATG TCAACATCAC CAATCTGGAA TTTGAAATAT GTGGGGCCCT CGTGGAGGTA
AAGTGCCTGA ATTTCAGGAA ACTACAAGAG ATATATTTCA TCGAGACAAA GAAATTCTTA
CTGATTGGAA AGAGCAATAT ATGTGTGAAG GTTGGAGAAA AGAGTCTAAC CTGCAAAAAA
ATAGACCTAA CCACTATAGT TAAACCTGAG GCTCCTTTTG ACCTGAGTGT CGTCTATCGG
GAAGGAGCCA ATGACTTTGT GGTGACATTT AATACATCAC ACTTGCAAAA GAAGTATGTA
AAAGTTTTAA TGCACGATGT AGCTTACCGC CAGGAAAAGG ATGAAAACAA ATGGACGCAT
GTGAATTTAT CCAGCACAAA GCTGACACTC CTGCAGAGAA AGCTCCAACC GGCAGCAATG
TATGAGATTA AAGTTCGATC CATCCCTGAT CACTATTTTA AAGGCTTCTG GAGTGAATGG
AGTCCAAGTT ATTACTTCAG AACTCCAGAG ATCAATAATA GCTCAGGATT AAGCCTATCG
TATGGCCCAG TCTCCCCGAT CATAAGAAGA CTCTGGAACA TCTTTGTAAG AAACCAAGAA
AAGTGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqXP_005248357.1
CDS89..874
Misc Feature(1)593..772(+)
Misc Feature(2)677..736(+)
Misc Feature(3)737..751(+)
Translation
Position Chain Variation Link
5 5 c, t dbSNP:200523830
50 50 c, t dbSNP:201511279
60 60 a, g dbSNP:200169985
64 64 -, ct dbSNP:760977768
65 65 -, ctct dbSNP:764329514
65 65 -, ct dbSNP:775874510
67 67 a, c dbSNP:543865837
72 72 c, t dbSNP:200201139
73 73 c, g, t dbSNP:369139531
77 77 a, c, g dbSNP:200964795
78 78 a, t dbSNP:747999593
81 81 c, g dbSNP:758373857
85 85 c, g dbSNP:202196214
90 90 g, t dbSNP:200076125
105 105 c, t dbSNP:771047572
114 114 a, c, g dbSNP:776642878
115 115 c, t dbSNP:770050857
116 116 a, g dbSNP:145097494
120 120 c, t dbSNP:539820821
139 139 a, c, t dbSNP:138981776
148 148 a, t dbSNP:780995324
156 156 c, g dbSNP:760033705
164 164 c, t dbSNP:202007062
169 169 a, t dbSNP:753451294
175 175 c, t dbSNP:370292681
185 185 a, g dbSNP:140673282
191 191 a, c dbSNP:752402991
192 192 a, t dbSNP:35967524
199 199 c, t dbSNP:763937095
201 201 a, t dbSNP:751358220
216 216 a, g dbSNP:373694709
220 220 a, c, t dbSNP:11567704
223 223 g, t dbSNP:200464578
237 237 g, t dbSNP:202083738
240 240 c, g, t dbSNP:138482569
241 241 a, g dbSNP:149235072
244 244 g, t dbSNP:768814999
245 245 c, t dbSNP:779308643
253 253 a, g dbSNP:748495760
256 256 c, t dbSNP:267600609
262 262 -, t dbSNP:765287425
266 266 a, g dbSNP:772586152
277 277 g, t dbSNP:773872375
285 285 c, t dbSNP:1494558
296 296 a, g dbSNP:769426499
299 299 g, t dbSNP:775198948
300 300 a, c, t dbSNP:147423300
302 302 c, g dbSNP:148001159
315 315 c, t dbSNP:755030275
318 318 -, t dbSNP:766399441
320 320 a, g, t dbSNP:200687605
325 325 g, t dbSNP:552630274
327 327 c, t dbSNP:200475138
331 331 a, g dbSNP:747417170
333 333 g, t dbSNP:757797163
334 334 a, c dbSNP:201767916
353 353 c, t dbSNP:141698985
368 368 -, atatatttca dbSNP:193922640
370 370 c, t dbSNP:778067695
371 371 a, g dbSNP:191585195
378 378 a, c, g dbSNP:773973629
387 387 -, tac dbSNP:751425932
388 388 a, t dbSNP:771757728
389 389 c, t dbSNP:772953676
394 394 a, c, t dbSNP:200241281
395 395 a, g dbSNP:201106853
396 396 c, g dbSNP:776441054
397 397 a, g dbSNP:759585748
401 401 a, c dbSNP:199742437
402 402 a, g dbSNP:150051812
403 403 c, t dbSNP:201058754
407 407 a, g dbSNP:764440449
411 411 a, g dbSNP:751922549
413 413 a, g dbSNP:757709286
414 414 c, t dbSNP:781675111
420 420 c, g, t dbSNP:548638151
421 421 c, t dbSNP:199641706
423 423 g, t dbSNP:778262602
424 424 a, g dbSNP:200817423
427 427 a, c dbSNP:11567735
428 428 a, g dbSNP:771667604
430 430 c, g dbSNP:777419876
431 431 a, g dbSNP:746743911
432 432 -, tcta dbSNP:754784201
432 432 c, g dbSNP:537367054
441 441 a, g dbSNP:193922641
442 442 -, a dbSNP:781000678
446 446 a, g dbSNP:200506624
447 447 a, t dbSNP:201710684
451 451 a, c dbSNP:769810965
454 454 a, c dbSNP:140473900
461 461 a, g dbSNP:145407742
464 464 a, c, g dbSNP:201207454
466 466 a, g dbSNP:762188432
468 468 g, t dbSNP:751109965
473 473 c, t dbSNP:756821231
474 474 c, t dbSNP:780917994
479 479 c, g dbSNP:745590108
482 482 c, t dbSNP:104893894
490 490 c, t dbSNP:780061831
492 492 g, t dbSNP:199779006
493 493 c, g dbSNP:768760071
495 495 a, g dbSNP:201012821
499 499 c, t dbSNP:545307253
500 500 a, g dbSNP:1494555
503 503 g, t dbSNP:772130250
506 506 c, t dbSNP:773491081
507 507 a, g dbSNP:200373233
512 512 a, g dbSNP:200772681
515 515 a, g dbSNP:372676633
521 521 a, g dbSNP:201790329
526 526 a, t dbSNP:587778403
527 527 -, g dbSNP:747698244
527 527 g, t dbSNP:760005945
528 528 c, t dbSNP:765765854
529 529 a, g dbSNP:750985822
530 530 c, g dbSNP:200332345
531 531 g, t dbSNP:767009659
534 534 c, t dbSNP:201940568
544 544 a, c, g dbSNP:112805866
548 548 c, t dbSNP:199727195
550 550 a, c dbSNP:749131336
554 554 c, t dbSNP:139221577
556 556 a, g dbSNP:112368558
564 564 a, t dbSNP:779013920
565 565 c, t dbSNP:748111926
567 567 -, t dbSNP:755779539
569 569 a, g dbSNP:200233367
578 578 a, t dbSNP:772191954
579 579 c, t dbSNP:771957502
582 582 a, c dbSNP:747236451
583 583 c, g, t dbSNP:2228141
584 584 a, g dbSNP:776941426
589 589 a, t dbSNP:199697302
591 591 c, t dbSNP:759917852
596 596 c, t dbSNP:145210284
597 597 a, g, t dbSNP:149161098
600 600 a, c dbSNP:531875566
603 603 a, g dbSNP:199654814
605 605 a, c dbSNP:749945425
607 607 a, g dbSNP:143661008
608 608 a, g dbSNP:375672744
616 616 a, c dbSNP:149833809
621 621 a, g dbSNP:753635194
622 622 a, g dbSNP:754827305
623 623 a, g dbSNP:778642997
624 624 a, c, t dbSNP:200751605
625 625 a, g dbSNP:758320927
626 626 c, t dbSNP:780435478
627 627 a, c dbSNP:193922642
628 628 c, t dbSNP:201040470
629 629 a, g dbSNP:62351970
630 630 c, t dbSNP:774732191
640 640 c, g, t dbSNP:748733640
647 647 a, g dbSNP:776330345
649 649 a, g, t dbSNP:11567764
658 658 c, g dbSNP:200528373
660 660 -, g dbSNP:777217507
661 661 g, t dbSNP:775310578
673 673 c, t dbSNP:762673467
678 678 c, t dbSNP:587778404
679 679 a, g dbSNP:201431556
682 682 a, c dbSNP:191457074
684 684 c, t dbSNP:767559651
687 687 a, t dbSNP:750537570
688 688 a, g dbSNP:754172661
690 690 a, g dbSNP:145810271
691 691 c, t dbSNP:200388101
704 704 cg, ta dbSNP:193922643
704 704 c, t dbSNP:201559094
705 705 a, g, t dbSNP:193922644
706 706 a, g dbSNP:755300062
708 708 c, g dbSNP:779479151
713 713 c, t dbSNP:748643880
717 717 a, t dbSNP:757795302
718 718 a, t dbSNP:772747002
723 723 a, g dbSNP:577344998
724 724 g, t dbSNP:786205572
732 732 g, t dbSNP:193922645
739 739 a, g dbSNP:104893893
741 741 a, g dbSNP:374232919
750 750 g, t dbSNP:587778405
754 754 a, c dbSNP:769433714
768 768 a, g dbSNP:148165103
770 770 a, c dbSNP:762736419
771 771 c, t dbSNP:201412341
773 773 c, t dbSNP:774177784
780 780 c, t dbSNP:761704139
783 783 a, g dbSNP:199714011
787 787 c, t dbSNP:566889429
789 789 c, g dbSNP:200894429
790 790 a, c dbSNP:201897242
792 792 c, t dbSNP:766555082
793 793 a, c dbSNP:753994938
801 801 a, g dbSNP:199814261
805 805 a, g dbSNP:773614197
807 807 c, t dbSNP:200468194
808 808 a, g dbSNP:369971728
825 825 a, c, t dbSNP:766895607
826 826 a, g dbSNP:201449880
839 839 c, t dbSNP:373309714
855 855 c, t dbSNP:375706394
869 869 -, agtg dbSNP:747377117
871 871 -, tgagtgtt dbSNP:768950875

Target ORF information:

RefSeq Version XM_005248300
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens interleukin 7 receptor (IL7R), transcript variant X3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_005248300

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGACAATTC TAGGTACAAC TTTTGGCATG GTTTTTTCTT TACTTCAAGT CGTTTCTGGA 
GAAAGTGGCT ATGCTCAAAA TGGAGACTTG GAAGATGCAG AACTGGATGA CTACTCATTC
TCATGCTATA GCCAGTTGGA AGTGAATGGA TCGCAGCACT CACTGACCTG TGCTTTTGAG
GACCCAGATG TCAACATCAC CAATCTGGAA TTTGAAATAT GTGGGGCCCT CGTGGAGGTA
AAGTGCCTGA ATTTCAGGAA ACTACAAGAG ATATATTTCA TCGAGACAAA GAAATTCTTA
CTGATTGGAA AGAGCAATAT ATGTGTGAAG GTTGGAGAAA AGAGTCTAAC CTGCAAAAAA
ATAGACCTAA CCACTATAGT TAAACCTGAG GCTCCTTTTG ACCTGAGTGT CGTCTATCGG
GAAGGAGCCA ATGACTTTGT GGTGACATTT AATACATCAC ACTTGCAAAA GAAGTATGTA
AAAGTTTTAA TGCACGATGT AGCTTACCGC CAGGAAAAGG ATGAAAACAA ATGGACGCAT
GTGAATTTAT CCAGCACAAA GCTGACACTC CTGCAGAGAA AGCTCCAACC GGCAGCAATG
TATGAGATTA AAGTTCGATC CATCCCTGAT CACTATTTTA AAGGCTTCTG GAGTGAATGG
AGTCCAAGTT ATTACTTCAG AACTCCAGAG ATCAATAATA GCTCAGGATT AAGCCTATCG
TATGGCCCAG TCTCCCCGAT CATAAGAAGA CTCTGGAACA TCTTTGTAAG AAACCAAGAA
AAGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu24651
Accession Version NM_002185.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1380bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector Document: User manual_GenEZ ORF Clone Products.pdf (pdf)
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags Document: MSDS_GenEZ ORF Clone Products.pdf (pdf)
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear Document: OHu24651D_COA.pdf (pdf)
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product interleukin-7 receptor subunit alpha precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CD703890.1, BC020717.1, BC067540.1, AC112204.2 and AF373204.1. On Jun 14, 2012 this sequence version replaced gi:28610150. Summary: The protein encoded by this gene is a receptor for interleukine 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukine 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in the V(D)J recombination during lymphocyte development. This protein is also found to control the accessibility of the TCR gamma locus by STAT5 and histone acetylation. Knockout studies in mice suggested that blocking apoptosis is an essential function of this protein during differentiation and activation of T lymphocytes. The functional defects in this protein may be associated with the pathogenesis of the severe combined immunodeficiency (SCID). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2014]. Transcript Variant: This variant (1) encodes a functional protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M29696.1, BC067537.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
ATGACAATTC TAGGTACAAC TTTTGGCATG GTTTTTTCTT TACTTCAAGT CGTTTCTGGA 
GAAAGTGGCT ATGCTCAAAA TGGAGACTTG GAAGATGCAG AACTGGATGA CTACTCATTC
TCATGCTATA GCCAGTTGGA AGTGAATGGA TCGCAGCACT CACTGACCTG TGCTTTTGAG
GACCCAGATG TCAACATCAC CAATCTGGAA TTTGAAATAT GTGGGGCCCT CGTGGAGGTA
AAGTGCCTGA ATTTCAGGAA ACTACAAGAG ATATATTTCA TCGAGACAAA GAAATTCTTA
CTGATTGGAA AGAGCAATAT ATGTGTGAAG GTTGGAGAAA AGAGTCTAAC CTGCAAAAAA
ATAGACCTAA CCACTATAGT TAAACCTGAG GCTCCTTTTG ACCTGAGTGT CGTCTATCGG
GAAGGAGCCA ATGACTTTGT GGTGACATTT AATACATCAC ACTTGCAAAA GAAGTATGTA
AAAGTTTTAA TGCACGATGT AGCTTACCGC CAGGAAAAGG ATGAAAACAA ATGGACGCAT
GTGAATTTAT CCAGCACAAA GCTGACACTC CTGCAGAGAA AGCTCCAACC GGCAGCAATG
TATGAGATTA AAGTTCGATC CATCCCTGAT CACTATTTTA AAGGCTTCTG GAGTGAATGG
AGTCCAAGTT ATTACTTCAG AACTCCAGAG ATCAATAATA GCTCAGGGGA GATGGATCCT
ATCTTACTAA CCATCAGCAT TTTGAGTTTT TTCTCTGTCG CTCTGTTGGT CATCTTGGCC
TGTGTGTTAT GGAAAAAAAG GATTAAGCCT ATCGTATGGC CCAGTCTCCC CGATCATAAG
AAGACTCTGG AACATCTTTG TAAGAAACCA AGAAAAAATT TAAATGTGAG TTTCAATCCT
GAAAGTTTCC TGGACTGCCA GATTCATAGG GTGGATGACA TTCAAGCTAG AGATGAAGTG
GAAGGTTTTC TGCAAGATAC GTTTCCTCAG CAACTAGAAG AATCTGAGAA GCAGAGGCTT
GGAGGGGATG TGCAGAGCCC CAACTGCCCA TCTGAGGATG TAGTCATCAC TCCAGAAAGC
TTTGGAAGAG ATTCATCCCT CACATGCCTG GCTGGGAATG TCAGTGCATG TGACGCCCCT
ATTCTCTCCT CTTCCAGGTC CCTAGACTGC AGGGAGAGTG GCAAGAATGG GCCTCATGTG
TACCAGGACC TCCTGCTTAG CCTTGGGACT ACAAACAGCA CGCTGCCCCC TCCATTTTCT
CTCCAATCTG GAATCCTGAC ATTGAACCCA GTTGCTCAGG GTCAGCCCAT TCTTACTTCC
CTGGGATCAA ATCAAGAAGA AGCATATGTC ACCATGTCCA GCTTCTACCA AAACCAGTGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_002176.2
CDS104..1483
Misc Feature(1)608..787(+)
Misc Feature(2)692..751(+)
Misc Feature(3)752..766(+)
Misc Feature(4)752..766(+)
Misc Feature(5)821..895(+)
Misc Feature(6)917..943(+)
Misc Feature(7)1448..1450(+)
Exon (1)1..185
Gene:IL7R
Gene Synonym:
Exon (2)186..324
Gene:IL7R
Gene Synonym:
Exon (3)325..482
Gene:IL7R
Gene Synonym:
Exon (4)483..640
Gene:IL7R
Gene Synonym:
Exon (5)641..809
Gene:IL7R
Gene Synonym:
Exon (6)810..903
Gene:IL7R
Gene Synonym:
Exon (7)904..979
Gene:IL7R
Gene Synonym:
Exon (8)980..3819
Gene:IL7R
Gene Synonym:
Translation
Position Chain Variation Link
3 3 c, t dbSNP:557325300
12 12 c, t dbSNP:113268638
20 20 c, t dbSNP:200523830
65 65 c, t dbSNP:201511279
75 75 a, g dbSNP:200169985
79 79 -, ct dbSNP:760977768
80 80 -, ctct dbSNP:764329514
80 80 -, ct dbSNP:775874510
82 82 a, c dbSNP:543865837
87 87 c, t dbSNP:200201139
88 88 c, g, t dbSNP:369139531
92 92 a, c, g dbSNP:200964795
93 93 a, t dbSNP:747999593
96 96 c, g dbSNP:758373857
100 100 c, g dbSNP:202196214
105 105 g, t dbSNP:200076125
120 120 c, t dbSNP:771047572
129 129 a, c, g dbSNP:776642878
130 130 c, t dbSNP:770050857
131 131 a, g dbSNP:145097494
135 135 c, t dbSNP:539820821
154 154 a, c, t dbSNP:138981776
163 163 a, t dbSNP:780995324
171 171 c, g dbSNP:760033705
179 179 c, t dbSNP:202007062
184 184 a, t dbSNP:753451294
190 190 c, t dbSNP:370292681
200 200 a, g dbSNP:140673282
206 206 a, c dbSNP:752402991
207 207 a, t dbSNP:35967524
214 214 c, t dbSNP:763937095
216 216 a, t dbSNP:751358220
231 231 a, g dbSNP:373694709
235 235 a, c, t dbSNP:11567704
238 238 g, t dbSNP:200464578
252 252 g, t dbSNP:202083738
255 255 c, g, t dbSNP:138482569
256 256 a, g dbSNP:149235072
259 259 g, t dbSNP:768814999
260 260 c, t dbSNP:779308643
268 268 a, g dbSNP:748495760
271 271 c, t dbSNP:267600609
277 277 -, t dbSNP:765287425
281 281 a, g dbSNP:772586152
292 292 g, t dbSNP:773872375
300 300 c, t dbSNP:1494558
311 311 a, g dbSNP:769426499
314 314 g, t dbSNP:775198948
315 315 a, c, t dbSNP:147423300
317 317 c, g dbSNP:148001159
330 330 c, t dbSNP:755030275
333 333 -, t dbSNP:766399441
335 335 a, g, t dbSNP:200687605
340 340 g, t dbSNP:552630274
342 342 c, t dbSNP:200475138
346 346 a, g dbSNP:747417170
348 348 g, t dbSNP:757797163
349 349 a, c dbSNP:201767916
368 368 c, t dbSNP:141698985
383 383 -, atatatttca dbSNP:193922640
385 385 c, t dbSNP:778067695
386 386 a, g dbSNP:191585195
393 393 a, c, g dbSNP:773973629
402 402 -, tac dbSNP:751425932
403 403 a, t dbSNP:771757728
404 404 c, t dbSNP:772953676
409 409 a, c, t dbSNP:200241281
410 410 a, g dbSNP:201106853
411 411 c, g dbSNP:776441054
412 412 a, g dbSNP:759585748
416 416 a, c dbSNP:199742437
417 417 a, g dbSNP:150051812
418 418 c, t dbSNP:201058754
422 422 a, g dbSNP:764440449
426 426 a, g dbSNP:751922549
428 428 a, g dbSNP:757709286
429 429 c, t dbSNP:781675111
435 435 c, g, t dbSNP:548638151
436 436 c, t dbSNP:199641706
438 438 g, t dbSNP:778262602
439 439 a, g dbSNP:200817423
442 442 a, c dbSNP:11567735
443 443 a, g dbSNP:771667604
445 445 c, g dbSNP:777419876
446 446 a, g dbSNP:746743911
447 447 -, tcta dbSNP:754784201
447 447 c, g dbSNP:537367054
456 456 a, g dbSNP:193922641
457 457 -, a dbSNP:781000678
461 461 a, g dbSNP:200506624
462 462 a, t dbSNP:201710684
466 466 a, c dbSNP:769810965
469 469 a, c dbSNP:140473900
476 476 a, g dbSNP:145407742
479 479 a, c, g dbSNP:201207454
481 481 a, g dbSNP:762188432
483 483 g, t dbSNP:751109965
488 488 c, t dbSNP:756821231
489 489 c, t dbSNP:780917994
494 494 c, g dbSNP:745590108
497 497 c, t dbSNP:104893894
505 505 c, t dbSNP:780061831
507 507 g, t dbSNP:199779006
508 508 c, g dbSNP:768760071
510 510 a, g dbSNP:201012821
514 514 c, t dbSNP:545307253
515 515 a, g dbSNP:1494555
518 518 g, t dbSNP:772130250
521 521 c, t dbSNP:773491081
522 522 a, g dbSNP:200373233
527 527 a, g dbSNP:200772681
530 530 a, g dbSNP:372676633
536 536 a, g dbSNP:201790329
541 541 a, t dbSNP:587778403
542 542 -, g dbSNP:747698244
542 542 g, t dbSNP:760005945
543 543 c, t dbSNP:765765854
544 544 a, g dbSNP:750985822
545 545 c, g dbSNP:200332345
546 546 g, t dbSNP:767009659
549 549 c, t dbSNP:201940568
559 559 a, c, g dbSNP:112805866
563 563 c, t dbSNP:199727195
565 565 a, c dbSNP:749131336
569 569 c, t dbSNP:139221577
571 571 a, g dbSNP:112368558
579 579 a, t dbSNP:779013920
580 580 c, t dbSNP:748111926
582 582 -, t dbSNP:755779539
584 584 a, g dbSNP:200233367
593 593 a, t dbSNP:772191954
594 594 c, t dbSNP:771957502
597 597 a, c dbSNP:747236451
598 598 c, g, t dbSNP:2228141
599 599 a, g dbSNP:776941426
604 604 a, t dbSNP:199697302
606 606 c, t dbSNP:759917852
611 611 c, t dbSNP:145210284
612 612 a, g, t dbSNP:149161098
615 615 a, c dbSNP:531875566
618 618 a, g dbSNP:199654814
620 620 a, c dbSNP:749945425
622 622 a, g dbSNP:143661008
623 623 a, g dbSNP:375672744
631 631 a, c dbSNP:149833809
636 636 a, g dbSNP:753635194
637 637 a, g dbSNP:754827305
638 638 a, g dbSNP:778642997
639 639 a, c, t dbSNP:200751605
640 640 a, g dbSNP:758320927
641 641 c, t dbSNP:780435478
642 642 a, c dbSNP:193922642
643 643 c, t dbSNP:201040470
644 644 a, g dbSNP:62351970
645 645 c, t dbSNP:774732191
655 655 c, g, t dbSNP:748733640
662 662 a, g dbSNP:776330345
664 664 a, g, t dbSNP:11567764
673 673 c, g dbSNP:200528373
675 675 -, g dbSNP:777217507
676 676 g, t dbSNP:775310578
688 688 c, t dbSNP:762673467
693 693 c, t dbSNP:587778404
694 694 a, g dbSNP:201431556
697 697 a, c dbSNP:191457074
699 699 c, t dbSNP:767559651
702 702 a, t dbSNP:750537570
703 703 a, g dbSNP:754172661
705 705 a, g dbSNP:145810271
706 706 c, t dbSNP:200388101
719 719 cg, ta dbSNP:193922643
719 719 c, t dbSNP:201559094
720 720 a, g, t dbSNP:193922644
721 721 a, g dbSNP:755300062
723 723 c, g dbSNP:779479151
728 728 c, t dbSNP:748643880
732 732 a, t dbSNP:757795302
733 733 a, t dbSNP:772747002
738 738 a, g dbSNP:577344998
739 739 g, t dbSNP:786205572
747 747 g, t dbSNP:193922645
754 754 a, g dbSNP:104893893
756 756 a, g dbSNP:374232919
765 765 g, t dbSNP:587778405
769 769 a, c dbSNP:769433714
783 783 a, g dbSNP:148165103
785 785 a, c dbSNP:762736419
786 786 c, t dbSNP:201412341
788 788 c, t dbSNP:774177784
795 795 c, t dbSNP:761704139
798 798 a, g dbSNP:199714011
802 802 c, t dbSNP:566889429
804 804 c, g dbSNP:200894429
805 805 a, c dbSNP:201897242
807 807 c, t dbSNP:766555082
808 808 a, c dbSNP:753994938
810 810 a, g dbSNP:201084372
812 812 a, g dbSNP:372056746
814 814 a, g dbSNP:778351803
824 824 a, g dbSNP:141111406
829 829 a, c dbSNP:751999018
834 834 c, t dbSNP:6897932
840 840 g, t dbSNP:779397627
847 847 c, g dbSNP:200086692
850 850 -, t dbSNP:748801798
862 862 c, t dbSNP:201268331
863 863 a, c, g, t dbSNP:137868226
868 868 a, g dbSNP:143438470
874 874 c, t dbSNP:760499889
875 875 a, g, t dbSNP:200150755
876 876 c, t dbSNP:549460344
878 878 g, t dbSNP:559933153
881 881 a, g dbSNP:147153824
894 894 a, g dbSNP:752967041
898 898 a, g dbSNP:548783574
902 902 a, c dbSNP:764528268
910 910 a, g dbSNP:199814261
914 914 a, g dbSNP:773614197
916 916 c, t dbSNP:200468194
917 917 a, g dbSNP:369971728
934 934 a, c, t dbSNP:766895607
935 935 a, g dbSNP:201449880
948 948 c, t dbSNP:373309714
964 964 c, t dbSNP:375706394
978 978 -, agtg dbSNP:747377117
985 985 a, c dbSNP:193922647
988 988 -, t dbSNP:786205646
1001 1001 -, cctga dbSNP:763041846
1007 1007 a, c, g dbSNP:771361407
1011 1011 c, g, t dbSNP:200107390
1018 1018 c, t dbSNP:200889239
1019 1019 a, t dbSNP:748055663
1022 1022 a, c dbSNP:751073911
1042 1042 c, t dbSNP:761483945
1043 1043 a, g dbSNP:202060571
1046 1046 c, g dbSNP:767298556
1053 1053 a, c, g dbSNP:755809849
1055 1055 a, g dbSNP:200521932
1060 1060 a, c, t dbSNP:201275186
1061 1061 g, t dbSNP:202226690
1062 1062 g, t dbSNP:140979277
1068 1068 g, t dbSNP:754918897
1075 1075 a, g dbSNP:779019330
1081 1081 c, t dbSNP:370440024
1083 1083 c, g, t dbSNP:536561203
1084 1084 a, g dbSNP:200211847
1089 1089 c, t dbSNP:747299332
1093 1093 a, c, g dbSNP:201093124
1103 1103 a, g dbSNP:777033414
1106 1106 c, t dbSNP:199735993
1110 1110 a, g dbSNP:770237630
1114 1114 a, g dbSNP:773859083
1120 1120 g, t dbSNP:761241127
1121 1121 c, t dbSNP:767208665
1123 1123 c, g, t dbSNP:138731184
1124 1124 g, t dbSNP:766254348
1125 1125 a, g dbSNP:753614229
1128 1128 a, g dbSNP:754897111
1129 1129 a, g dbSNP:201058934
1138 1138 c, g dbSNP:765101557
1145 1145 a, g dbSNP:752755761
1146 1146 a, c, g dbSNP:41270321
1149 1149 a, c, g, t dbSNP:200927791
1151 1151 c, t dbSNP:111803690
1160 1160 a, g dbSNP:770274946
1165 1165 a, g dbSNP:775861133
1166 1166 a, g dbSNP:749870381
1169 1169 a, g dbSNP:3194051
1174 1174 c, t dbSNP:142726694
1178 1178 g, t dbSNP:1803814
1179 1179 a, c dbSNP:200629583
1180 1180 a, c dbSNP:201722571
1185 1185 c, g, t dbSNP:200061456
1193 1193 a, g dbSNP:149811361
1195 1195 g, t dbSNP:201216012
1199 1199 c, t dbSNP:201671392
1200 1200 c, t dbSNP:778728560
1202 1202 c, t dbSNP:587778406
1203 1203 c, t dbSNP:765146917
1207 1207 a, g dbSNP:752565106
1209 1209 g, t dbSNP:758381888
1210 1210 a, c dbSNP:199803084
1212 1212 a, t dbSNP:374876660
1218 1218 a, g, t dbSNP:201146815
1230 1230 a, c dbSNP:751674240
1233 1233 g, t dbSNP:757426044
1237 1237 c, g, t dbSNP:150593442
1238 1238 a, g dbSNP:200570812
1242 1242 c, g dbSNP:780521625
1245 1245 c, t dbSNP:749788439
1247 1247 c, g dbSNP:769324453
1253 1253 c, t dbSNP:200775167
1259 1259 a, g dbSNP:772808332
1260 1260 a, g dbSNP:201790771
1262 1262 c, t dbSNP:770641220
1264 1264 c, t dbSNP:139678300
1268 1268 c, g dbSNP:143596606
1270 1270 a, c dbSNP:201298914
1272 1272 g, t dbSNP:370396298
1279 1279 a, c, g dbSNP:764922920
1285 1285 c, t dbSNP:563086691
1291 1291 c, t dbSNP:145705481
1293 1293 c, g dbSNP:200217234
1303 1303 a, g dbSNP:140634356
1313 1313 c, t dbSNP:761882064
1324 1324 c, t dbSNP:267600610
1330 1330 a, g dbSNP:767700045
1334 1334 a, g dbSNP:115316501
1340 1340 a, t dbSNP:368172701
1341 1341 a, c, g dbSNP:756406426
1344 1344 c, t dbSNP:2229232
1345 1345 a, g dbSNP:755492743
1348 1348 a, g dbSNP:547350466
1353 1353 c, t dbSNP:201661275
1355 1355 c, g dbSNP:199666194
1359 1359 c, t dbSNP:149195024
1362 1362 a, c dbSNP:748731611
1368 1368 a, c dbSNP:770335655
1369 1369 a, g dbSNP:201755068
1394 1394 a, g dbSNP:745481948
1402 1402 c, g dbSNP:200165388
1406 1406 c, g dbSNP:371681482
1411 1411 c, t dbSNP:368296149
1419 1419 c, g dbSNP:148931962
1426 1426 a, g dbSNP:762754248
1434 1434 a, g dbSNP:151326413
1441 1441 a, g dbSNP:112890868
1456 1456 c, t dbSNP:201947153
1459 1459 a, g dbSNP:774263590
1460 1460 c, t dbSNP:141919625
1461 1461 a, c dbSNP:767469485
1464 1464 g, t dbSNP:750554449
1465 1465 c, t dbSNP:760766611
1466 1466 c, t dbSNP:766645405
1500 1500 a, g dbSNP:201020485
1501 1501 c, t dbSNP:377463049
1506 1506 c, g dbSNP:779480750
1514 1514 a, g dbSNP:548171868
1517 1517 a, c, t dbSNP:201713518
1518 1518 a, g dbSNP:758988107
1519 1519 a, t dbSNP:780530930
1523 1523 a, g dbSNP:199882238
1525 1525 a, g, t dbSNP:145513117
1528 1528 a, t dbSNP:749002533
1541 1541 a, g dbSNP:576269217
1569 1569 a, c dbSNP:202075594
1588 1588 c, g dbSNP:200590959
1594 1594 a, c dbSNP:138148579
1604 1604 a, g dbSNP:202200371
1618 1618 a, t dbSNP:112348735
1619 1619 a, g dbSNP:200395973
1630 1630 c, t dbSNP:201394819
1633 1633 a, c dbSNP:771415130
1636 1636 a, g dbSNP:199768633
1638 1638 c, t dbSNP:190597330
1662 1662 a, g dbSNP:140969613
1694 1694 c, t dbSNP:199673589
1716 1716 c, g dbSNP:144757435
1733 1733 c, g dbSNP:201645441
1739 1739 -, a dbSNP:537952635
1739 1739 a, t dbSNP:574373069
1740 1740 -, a dbSNP:202167692
1749 1749 -, c dbSNP:770306810
1771 1771 a, g dbSNP:200036308
1783 1783 a, c dbSNP:200526971
1805 1805 a, g dbSNP:201512867
1810 1810 a, t dbSNP:563155310
1815 1815 -, gaaa dbSNP:145416689
1815 1815 a, g dbSNP:200134977
1816 1816 -, aaag dbSNP:11567767
1823 1823 -, agaa dbSNP:140734994
1828 1828 -, aaag dbSNP:397691511
1829 1829 a, g dbSNP:200767455
1833 1833 a, g dbSNP:202195454
1835 1835 a, t dbSNP:200083526
1849 1849 g, t dbSNP:201380627
1866 1866 a, t dbSNP:774709817
1897 1897 a, g dbSNP:531884644
1913 1913 c, t dbSNP:760126842
1916 1916 c, t dbSNP:764721661
1936 1936 g, t dbSNP:79286909
1952 1952 c, t dbSNP:369100388
1953 1953 a, g dbSNP:527912791
1959 1959 c, t dbSNP:774999204
1974 1974 a, t dbSNP:547845372
1991 1991 a, g dbSNP:74625608
2025 2025 a, g dbSNP:760279848
2035 2035 a, g dbSNP:148253481
2044 2044 a, g dbSNP:181945634
2129 2129 c, t dbSNP:569906853
2130 2130 a, g dbSNP:538953523
2134 2134 c, g dbSNP:77118170
2146 2146 a, t dbSNP:763740085
2157 2157 a, g dbSNP:565860240
2159 2159 g, t dbSNP:762308822
2178 2178 a, c dbSNP:11567768
2205 2205 c, t dbSNP:370147033
2207 2207 c, t dbSNP:756986909
2262 2262 a, g dbSNP:374347576
2270 2270 a, g dbSNP:765148827
2275 2275 c, t dbSNP:554640590
2313 2313 a, c dbSNP:11567769
2331 2331 a, g dbSNP:141201259
2348 2348 c, g dbSNP:184482643
2384 2384 a, c dbSNP:576294390
2400 2400 a, g dbSNP:10063294
2421 2421 g, t dbSNP:189056705
2434 2434 g, t dbSNP:527874301
2457 2457 c, g dbSNP:750628294
2464 2464 g, t dbSNP:150755607
2502 2502 a, c dbSNP:561389484
2509 2509 c, t dbSNP:530160313
2510 2510 a, g dbSNP:374784603
2514 2514 a, g dbSNP:181322631
2515 2515 a, t dbSNP:374220579
2522 2522 a, g dbSNP:758411684
2535 2535 a, g dbSNP:538880169
2574 2574 a, g dbSNP:781372644
2588 2588 c, t dbSNP:563697159
2611 2611 c, g dbSNP:748273693
2631 2631 g, t dbSNP:758728594
2654 2654 a, g dbSNP:16902514
2659 2659 a, c dbSNP:779934180
2674 2674 a, g dbSNP:558789404
2715 2715 g, t dbSNP:80264384
2721 2721 a, t dbSNP:9292617
2736 2736 a, g, t dbSNP:10491435
2745 2745 c, g dbSNP:149458295
2751 2751 c, t dbSNP:554469686
2769 2769 c, g dbSNP:185636216
2775 2775 a, g dbSNP:771165703
2809 2809 a, g dbSNP:10491434
2846 2846 a, c dbSNP:557052811
2859 2859 c, t dbSNP:746308692
2896 2896 a, g dbSNP:576406252
2909 2909 g, t dbSNP:545436415
2911 2911 a, g dbSNP:772594719
2916 2916 c, t dbSNP:558812912
2939 2939 g, t dbSNP:190735139
2943 2943 g, t dbSNP:541587134
2972 2972 c, g dbSNP:774913403
2981 2981 c, t dbSNP:574777494
2989 2989 c, t dbSNP:77732174
2991 2991 c, g dbSNP:111740630
2992 2992 a, c dbSNP:760191548
3027 3027 a, g dbSNP:11567770
3028 3028 c, g dbSNP:1494575
3035 3035 a, g dbSNP:10053847
3061 3061 a, g dbSNP:371321031
3097 3097 c, t dbSNP:563820481
3102 3102 g, t dbSNP:113174267
3142 3142 a, g dbSNP:761569711
3144 3144 a, g dbSNP:7716064
3185 3185 a, c dbSNP:147528974
3189 3189 c, t dbSNP:777574544
3191 3191 c, g dbSNP:528397389
3232 3232 c, t dbSNP:750255032
3266 3266 a, g dbSNP:762944456
3326 3326 a, t dbSNP:140174728
3373 3373 a, g dbSNP:568146201
3384 3384 -, c dbSNP:33994244
3385 3385 c, t dbSNP:187393408
3407 3407 a, g dbSNP:9292618
3457 3457 a, g dbSNP:145691961
3536 3536 a, g dbSNP:528405694
3543 3543 g, t dbSNP:756252554
3548 3548 a, g dbSNP:541801251
3568 3568 a, g dbSNP:539003484
3585 3585 a, t dbSNP:147298536
3648 3648 c, t dbSNP:76614394
3656 3656 a, g dbSNP:572371508
3666 3666 a, c dbSNP:753982280
3676 3676 a, g dbSNP:16902521
3691 3691 g, t dbSNP:114441625
3725 3725 a, c dbSNP:757519422
3743 3743 a, g dbSNP:555274790
3753 3753 c, g dbSNP:574931316
3769 3769 a, g dbSNP:377068522
3771 3771 g, t dbSNP:544035476
3777 3777 c, g dbSNP:563733521
3785 3785 a, c dbSNP:777326798
3822 3822 c, t dbSNP:6451231
3865 3865 c, t dbSNP:546190427
3878 3878 c, t dbSNP:559799468
3896 3896 g, t dbSNP:192345351
3912 3912 c, t dbSNP:548166315
3914 3914 a, g dbSNP:780523949
3937 3937 a, t dbSNP:6862072
3975 3975 a, t dbSNP:183660202
3990 3990 c, t dbSNP:6881270
4017 4017 a, g dbSNP:570163509
4030 4030 a, g dbSNP:13167136
4051 4051 g, t dbSNP:6881706
4060 4060 -, c dbSNP:755622568
4094 4094 -, t dbSNP:752829026
4111 4111 a, g dbSNP:148781726
4180 4180 a, c dbSNP:535482698
4187 4187 a, g dbSNP:554955538
4195 4195 c, t dbSNP:769517551
4213 4213 c, t dbSNP:575088330
4218 4218 c, t dbSNP:367670944
4233 4233 c, g dbSNP:6885455
4253 4253 a, g dbSNP:142305608
4280 4280 a, g dbSNP:1132841
4284 4284 a, c dbSNP:1132842
4289 4289 c, t dbSNP:565991507
4300 4300 a, c dbSNP:113393512
4324 4324 a, c, g, t dbSNP:1053496
4356 4356 c, t dbSNP:377053917
4357 4357 a, g dbSNP:559913836
4381 4381 a, g dbSNP:76863142
4439 4439 c, g dbSNP:542245287
4444 4444 a, g dbSNP:561791300
4464 4464 c, t dbSNP:759593338
4471 4471 c, t dbSNP:764027982
4478 4478 a, c, g dbSNP:72742450
4490 4490 a, c, g, t dbSNP:700179
4495 4495 c, t dbSNP:563926221
4498 4498 a, g dbSNP:1862632
4508 4508 g, t dbSNP:374172302
4509 4509 a, g dbSNP:529504735
4524 4524 c, t dbSNP:750702290
4525 4525 a, g dbSNP:151275799
4547 4547 c, t dbSNP:758755061
4561 4561 a, g dbSNP:1862633
4572 4572 c, t dbSNP:187963551

Target ORF information:

RefSeq Version NM_002185
Organism Homo sapiens (human)
Definition Homo sapiens interleukin 7 receptor (IL7R), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_002185

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
ATGACAATTC TAGGTACAAC TTTTGGCATG GTTTTTTCTT TACTTCAAGT CGTTTCTGGA 
GAAAGTGGCT ATGCTCAAAA TGGAGACTTG GAAGATGCAG AACTGGATGA CTACTCATTC
TCATGCTATA GCCAGTTGGA AGTGAATGGA TCGCAGCACT CACTGACCTG TGCTTTTGAG
GACCCAGATG TCAACATCAC CAATCTGGAA TTTGAAATAT GTGGGGCCCT CGTGGAGGTA
AAGTGCCTGA ATTTCAGGAA ACTACAAGAG ATATATTTCA TCGAGACAAA GAAATTCTTA
CTGATTGGAA AGAGCAATAT ATGTGTGAAG GTTGGAGAAA AGAGTCTAAC CTGCAAAAAA
ATAGACCTAA CCACTATAGT TAAACCTGAG GCTCCTTTTG ACCTGAGTGT CGTCTATCGG
GAAGGAGCCA ATGACTTTGT GGTGACATTT AATACATCAC ACTTGCAAAA GAAGTATGTA
AAAGTTTTAA TGCACGATGT AGCTTACCGC CAGGAAAAGG ATGAAAACAA ATGGACGCAT
GTGAATTTAT CCAGCACAAA GCTGACACTC CTGCAGAGAA AGCTCCAACC GGCAGCAATG
TATGAGATTA AAGTTCGATC CATCCCTGAT CACTATTTTA AAGGCTTCTG GAGTGAATGG
AGTCCAAGTT ATTACTTCAG AACTCCAGAG ATCAATAATA GCTCAGGGGA GATGGATCCT
ATCTTACTAA CCATCAGCAT TTTGAGTTTT TTCTCTGTCG CTCTGTTGGT CATCTTGGCC
TGTGTGTTAT GGAAAAAAAG GATTAAGCCT ATCGTATGGC CCAGTCTCCC CGATCATAAG
AAGACTCTGG AACATCTTTG TAAGAAACCA AGAAAAAATT TAAATGTGAG TTTCAATCCT
GAAAGTTTCC TGGACTGCCA GATTCATAGG GTGGATGACA TTCAAGCTAG AGATGAAGTG
GAAGGTTTTC TGCAAGATAC GTTTCCTCAG CAACTAGAAG AATCTGAGAA GCAGAGGCTT
GGAGGGGATG TGCAGAGCCC CAACTGCCCA TCTGAGGATG TAGTCATCAC TCCAGAAAGC
TTTGGAAGAG ATTCATCCCT CACATGCCTG GCTGGGAATG TCAGTGCATG TGACGCCCCT
ATTCTCTCCT CTTCCAGGTC CCTAGACTGC AGGGAGAGTG GCAAGAATGG GCCTCATGTG
TACCAGGACC TCCTGCTTAG CCTTGGGACT ACAAACAGCA CGCTGCCCCC TCCATTTTCT
CTCCAATCTG GAATCCTGAC ATTGAACCCA GTTGCTCAGG GTCAGCCCAT TCTTACTTCC
CTGGGATCAA ATCAAGAAGA AGCATATGTC ACCATGTCCA GCTTCTACCA AAACCAGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.