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KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1 [Homo sapiens (human)]

Gene Symbol KCNA1
Entrez Gene ID 3736
Full Name potassium channel, voltage gated shaker related subfamily A, member 1
Synonyms AEMK, EA1, HBK1, HUK1, KV1.1, MBK1, MK1, RBK1
General protein information
Preferred Names
potassium voltage-gated channel subfamily A member 1
Names
potassium voltage-gated channel subfamily A member 1
voltage-gated K(+) channel HuKI
voltage-gated potassium channel HBK1
voltage-gated potassium channel subunit Kv1.1
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

12

12p13.32

Summary This gene encodes a voltage-gated delayed potassium channel that is phylogenetically related to the Drosophila Shaker channel. The encoded protein has six putative transmembrane segments (S1-S6), and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif (GYGD). The functional channel is a homotetramer. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting. Mutations in this gene have been associated with myokymia with periodic ataxia (AEMK). [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

176260

Disorder Html: Episodic ataxia/myokymia syndrome, 160120 (3)
CloneID RefSeq Accession Definition **Vector *Turnaround time Price
OHu25897 NM_000217 Homo sapiens potassium channel, voltage gated shaker related subfamily A, member 1 (KCNA1), mRNA. pcDNA3.1-C-(k)DYK In stock 5-7 Starting from $99.00

*Business Day
**You may select a custom vector to replace pcDNA3.1-C-(k)DYK after clone is added to cart.



CloneID OHu25897D
Sequence Information ORF Nucleotide Sequence (Length: 1488bp)
Protein sequence
SNP
Vector pcDNA3.1-C-(k)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1-C-(k)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product potassium voltage-gated channel subfamily A member 1
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA236475.1 and AC006063.1. This sequence is a reference standard in the RefSeqGene project. On or before Dec 16, 2006 this sequence version replaced gi:113423206, gi:4557684. Summary: This gene encodes a voltage-gated delayed potassium channel that is phylogenetically related to the Drosophila Shaker channel. The encoded protein has six putative transmembrane segments (S1-S6), and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif (GYGD). The functional channel is a homotetramer. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting. Mutations in this gene have been associated with myokymia with periodic ataxia (AEMK). [provided by RefSeq, Jul 2008]. Sequence Note: This RefSeq record was created largely from genomic sequence because transcripts were not available for the entire length of the gene. This transcript is supported by sequences from mouse. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: DA236475.1, DA244238.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145743, SAMEA2154665 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
ATGACGGTGA TGTCTGGGGA GAACGTGGAC GAGGCTTCGG CCGCCCCGGG CCACCCCCAG 
GATGGCAGCT ACCCCCGGCA GGCCGACCAC GACGACCACG AGTGCTGCGA GCGCGTGGTG
ATCAACATCT CCGGGCTGCG CTTCGAGACG CAGCTCAAGA CCCTGGCGCA GTTCCCCAAC
ACGCTGCTGG GCAACCCTAA GAAACGCATG CGCTACTTCG ACCCCCTGAG GAACGAGTAC
TTCTTCGACC GCAACCGGCC CAGCTTCGAC GCCATCCTCT ACTACTACCA GTCCGGCGGC
CGCCTGCGGA GGCCGGTCAA CGTGCCCCTG GACATGTTCT CCGAGGAGAT CAAGTTTTAC
GAGTTGGGCG AGGAGGCCAT GGAGAAGTTC CGGGAGGACG AGGGCTTCAT CAAGGAGGAG
GAGCGCCCTC TGCCCGAGAA GGAGTACCAG CGCCAGGTGT GGCTGCTCTT CGAGTACCCC
GAGAGCTCGG GGCCCGCCAG GGTCATCGCC ATCGTCTCCG TCATGGTCAT CCTCATCTCC
ATCGTCATCT TTTGCCTGGA GACGCTCCCC GAGCTGAAGG ATGACAAGGA CTTCACGGGC
ACCGTCCACC GCATCGACAA CACCACGGTC ATCTACAATT CCAACATCTT CACAGACCCC
TTCTTCATCG TGGAAACGCT GTGTATCATC TGGTTCTCCT TCGAGCTGGT GGTGCGCTTC
TTCGCCTGCC CCAGCAAGAC GGACTTCTTC AAAAACATCA TGAACTTCAT AGACATTGTG
GCCATCATTC CTTATTTCAT CACGCTGGGC ACCGAGATAG CTGAGCAGGA AGGAAACCAG
AAGGGCGAGC AGGCCACCTC CCTGGCCATC CTCAGGGTCA TCCGCTTGGT AAGGGTTTTT
AGAATCTTCA AGCTCTCCCG CCACTCTAAG GGCCTCCAGA TCCTGGGCCA GACCCTCAAA
GCTAGTATGA GAGAGCTAGG GCTGCTCATC TTTTTCCTCT TCATCGGGGT CATCCTGTTT
TCTAGTGCAG TGTACTTTGC CGAGGCGGAA GAAGCTGAGT CGCACTTCTC CAGTATCCCC
GATGCTTTCT GGTGGGCGGT GGTGTCCATG ACCACTGTAG GATACGGTGA CATGTACCCT
GTGACAATTG GAGGCAAGAT CGTGGGCTCC TTGTGTGCCA TCGCTGGTGT GCTAACAATT
GCCCTGCCCG TACCTGTCAT TGTGTCCAAT TTCAACTATT TCTACCACCG AGAAACTGAG
GGGGAAGAGC AGGCTCAGTT GCTCCACGTC AGTTCCCCTA ACTTAGCCTC TGACAGTGAC
CTCAGTCGCC GCAGTTCCTC TACTATGAGC AAGTCTGAGT ACATGGAGAT CGAAGAGGAT
ATGAATAATA GCATAGCCCA TTATAGACAG GTCAATATCA GAACTGCCAA TTGCACCACT
GCTAACCAAA ACTGCGTTAA TAAGAGCAAG CTACTGACCG ATGTTTAA
The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.
RefSeqNP_000208.2
CDS1106..2593
Misc Feature(1)989..991(+)
Misc Feature(2)1220..1495(+)
Misc Feature(3)1607..1663(+)
Misc Feature(4)1766..1831(+)
Misc Feature(5)1772..2326(+)
Misc Feature(6)1865..1927(+)
Misc Feature(7)1973..2032(+)
Misc Feature(8)2069..2071(+)
Misc Feature(9)2081..2140(+)
Misc Feature(10)2099..2329(+)
Misc Feature(11)2219..2236(+)
Misc Feature(12)2264..2329(+)
Misc Feature(13)2438..2440(+)
Misc Feature(14)2582..2590(+)
Exon (1)1..566
Gene:KCNA1
Gene Synonym:
Exon (2)567..7983
Gene:KCNA1
Gene Synonym:
Translation
Position Chain Variation Link
9 9 c, g dbSNP:187214567
37 37 a, g dbSNP:552569395
58 58 g, t dbSNP:375367750
62 62 c, t dbSNP:369573644
63 63 c, t dbSNP:11831571
69 69 c, t dbSNP:780237417
79 79 c, t dbSNP:751585354
98 98 c, g dbSNP:527611519
112 112 c, g dbSNP:547369727
134 134 a, t dbSNP:747321050
147 147 c, t dbSNP:11831584
180 180 a, g, t dbSNP:192456145
231 231 c, t dbSNP:374196069
239 239 c, g dbSNP:143840582
240 240 -, ga dbSNP:566173456
240 240 c, g dbSNP:569380431
267 267 c, t dbSNP:12303537
306 306 g, t dbSNP:558160710
322 322 c, t dbSNP:571946369
340 340 c, g dbSNP:746125910
362 362 g, t dbSNP:183843080
363 363 a, c dbSNP:535369032
375 375 c, g dbSNP:74058081
388 388 a, t dbSNP:112643137
468 468 c, t dbSNP:574980784
472 472 a, g dbSNP:777396436
578 578 c, t dbSNP:528463485
581 581 a, g dbSNP:537497803
591 591 a, g dbSNP:547676064
622 622 -, g dbSNP:576931243
625 625 c, g dbSNP:560976682
628 628 -, g dbSNP:34346629
663 663 c, g dbSNP:749022231
678 678 c, t dbSNP:7307690
718 718 a, g dbSNP:774273695
752 752 c, g dbSNP:549601696
795 795 a, g dbSNP:569495059
812 812 a, g dbSNP:761552860
831 831 c, t dbSNP:538396272
871 871 a, c dbSNP:113587682
935 935 a, g dbSNP:565679233
949 949 a, t dbSNP:534276633
954 954 c, g dbSNP:543514434
972 972 g, t dbSNP:12817318
982 982 c, g dbSNP:573930602
996 996 a, g dbSNP:35678382
1004 1004 c, t dbSNP:537723793
1008 1008 g, t dbSNP:557615900
1010 1010 g, t dbSNP:28666907
1011 1011 g, t dbSNP:28388577
1016 1016 c, g dbSNP:577510278
1017 1017 a, g dbSNP:765802042
1020 1020 a, g dbSNP:546357890
1030 1030 c, t dbSNP:553150052
1034 1034 a, c dbSNP:573191253
1042 1042 c, g dbSNP:758976505
1055 1055 c, t dbSNP:766225126
1056 1056 c, g dbSNP:751176537
1071 1071 a, c dbSNP:754516764
1077 1077 a, g dbSNP:75906135
1085 1085 a, c dbSNP:752344044
1085 1085 -, c dbSNP:773463314
1086 1086 c, t dbSNP:757572774
1088 1088 a, c dbSNP:541828200
1089 1089 a, c, t dbSNP:746212583
1090 1090 a, g, t dbSNP:753446355
1093 1093 a, c dbSNP:201149627
1096 1096 a, g dbSNP:768682801
1106 1106 a, g dbSNP:776861490
1110 1110 c, g dbSNP:762038042
1111 1111 g, t dbSNP:769483045
1117 1117 a, g, t dbSNP:773128496
1121 1121 a, g dbSNP:754549386
1123 1123 c, g dbSNP:766476165
1124 1124 a, g dbSNP:529968149
1134 1134 a, g dbSNP:759152813
1144 1144 g, t dbSNP:767073909
1145 1145 g, t dbSNP:752293178
1147 1147 c, t dbSNP:375361885
1148 1148 g, t dbSNP:777276806
1149 1149 c, t dbSNP:543311674
1150 1150 a, c dbSNP:750848000
1158 1158 a, c dbSNP:367921276
1165 1165 c, g dbSNP:201504073
1166 1166 a, g dbSNP:747465523
1179 1179 c, t dbSNP:755064500
1181 1181 c, t dbSNP:373645838
1183 1183 c, g dbSNP:1063289
1189 1189 c, t dbSNP:748174897
1198 1198 c, t dbSNP:375647671
1204 1204 a, c dbSNP:773288048
1212 1212 a, g dbSNP:749152092
1213 1213 a, c dbSNP:770814681
1219 1219 c, t dbSNP:146308797
1223 1223 a, g dbSNP:759476808
1237 1237 c, g, t dbSNP:139476802
1241 1241 a, c dbSNP:149959487
1261 1261 c, g dbSNP:763846827
1264 1264 a, c, g dbSNP:370288610
1273 1273 g, t dbSNP:145042702
1284 1284 a, g dbSNP:752067203
1294 1294 a, g dbSNP:374515303
1301 1301 c, t dbSNP:552253837
1321 1321 c, t dbSNP:748311101
1342 1342 a, g dbSNP:149110871
1345 1345 c, t dbSNP:368673884
1360 1360 c, t dbSNP:749426849
1372 1372 c, t dbSNP:371963908
1378 1378 c, t dbSNP:770849823
1386 1386 a, g dbSNP:370669088
1399 1399 c, t dbSNP:745642062
1402 1402 c, g dbSNP:772182513
1420 1420 a, g dbSNP:372742714
1429 1429 a, g dbSNP:760261969
1435 1435 a, g dbSNP:763462393
1439 1439 a, g dbSNP:776360582
1447 1447 c, t dbSNP:761389490
1451 1451 c, g dbSNP:764866873
1454 1454 a, g dbSNP:201627497
1456 1456 a, c dbSNP:751980892
1457 1457 a, g dbSNP:755315825
1458 1458 a, g dbSNP:768113136
1459 1459 a, g dbSNP:375267715
1465 1465 c, t dbSNP:528107023
1471 1471 a, g dbSNP:756244699
1492 1492 a, g dbSNP:777644212
1498 1498 a, g dbSNP:142184899
1501 1501 a, g dbSNP:757607339
1504 1504 c, t dbSNP:779252925
1510 1510 c, t dbSNP:547910421
1513 1513 c, t dbSNP:372019704
1515 1515 c, t dbSNP:780062452
1530 1530 a, g dbSNP:746862982
1535 1535 c, t dbSNP:568025967
1537 1537 c, g dbSNP:368749626
1540 1540 c, g, t dbSNP:761301513
1541 1541 a, g dbSNP:772823472
1543 1543 a, g dbSNP:759928165
1550 1550 c, t dbSNP:767728993
1555 1555 a, g dbSNP:753264870
1571 1571 c, g dbSNP:761149222
1580 1580 c, t dbSNP:764645312
1586 1586 g, t dbSNP:754013861
1595 1595 g, t dbSNP:757392128
1596 1596 g, t dbSNP:779302041
1597 1597 c, g dbSNP:750634572
1618 1618 c, t dbSNP:758217449
1619 1619 a, g dbSNP:779656199
1624 1624 c, t dbSNP:746806471
1625 1625 g, t dbSNP:104894349
1635 1635 a, t dbSNP:267607195
1637 1637 a, c dbSNP:768541186
1656 1656 g, t dbSNP:104894357
1667 1667 a, g dbSNP:781075600
1669 1669 g, t dbSNP:747703770
1675 1675 c, g dbSNP:769242869
1682 1682 a, g dbSNP:772878919
1695 1695 a, t dbSNP:267603503
1716 1716 a, g dbSNP:2229000
1722 1722 a, g dbSNP:557677390
1736 1736 a, g dbSNP:775789299
1744 1744 g, t dbSNP:761073190
1746 1746 c, t dbSNP:764561596
1748 1748 a, g dbSNP:754350793
1749 1749 a, g dbSNP:762016621
1759 1759 a, t dbSNP:571062972
1768 1768 c, t dbSNP:200511296
1772 1772 a, g dbSNP:146948558
1774 1774 c, t dbSNP:766618582
1781 1781 a, g dbSNP:104894354
1782 1782 a, c, g, t dbSNP:28933383
1789 1789 c, t dbSNP:1048500
1792 1792 c, t dbSNP:754778573
1795 1795 a, c dbSNP:781127002
1801 1801 c, t dbSNP:748035400
1807 1807 a, c, t dbSNP:755621934
1815 1815 -, t dbSNP:749354093
1820 1820 a, c dbSNP:104894348
1821 1821 a, g dbSNP:748830362
1828 1828 c, t dbSNP:147731985
1829 1829 c, g dbSNP:28933381
1830 1830 c, t dbSNP:774035254
1832 1832 g, t dbSNP:140659450
1836 1836 a, c dbSNP:28933382
1837 1837 c, t dbSNP:769026957
1844 1844 a, g dbSNP:71582856
1850 1850 a, t dbSNP:104894356
1853 1853 -, ttc dbSNP:113994120
1861 1861 c, t dbSNP:777283636
1868 1868 a, g dbSNP:121918067
1879 1879 c, t dbSNP:762353539
1888 1888 c, t dbSNP:765825652
1892 1892 a, g dbSNP:377163970
1909 1909 a, c, g dbSNP:2227910
1912 1912 a, g dbSNP:751754423
1918 1918 c, g, t dbSNP:200737976
1926 1926 c, t dbSNP:373047882
1945 1945 a, g dbSNP:756115116
1954 1954 g, t dbSNP:777660284
1960 1960 a, c dbSNP:542289846
1973 1973 a, g dbSNP:376413513
1975 1975 c, t dbSNP:756744600
1989 1989 g, t dbSNP:778463081
2002 2002 a, t dbSNP:745459156
2012 2012 c, t dbSNP:555527499
2021 2021 c, t dbSNP:77865785
2032 2032 g, t dbSNP:748518926
2038 2038 a, c, g dbSNP:138351123
2048 2048 c, t dbSNP:71582857
2062 2062 c, t dbSNP:771000500
2080 2080 c, g dbSNP:104894353
2081 2081 c, t dbSNP:774438747
2089 2089 g, t dbSNP:565299396
2095 2095 a, c dbSNP:149635751
2100 2100 c, t dbSNP:752533303
2100 2100 -, t dbSNP:147887196
2110 2110 c, t dbSNP:760445014
2113 2113 a, g dbSNP:764044616
2116 2116 c, t dbSNP:575227161
2119 2119 a, c dbSNP:756726040
2120 2120 c, t dbSNP:372832102
2131 2131 c, t dbSNP:749888137
2143 2143 c, t dbSNP:758191529
2146 2146 c, t dbSNP:779820856
2152 2152 a, g dbSNP:748570236
2167 2167 a, g dbSNP:779989266
2221 2221 c, t dbSNP:770232444
2227 2227 a, c, t dbSNP:778171002
2230 2230 c, t dbSNP:144351014
2240 2240 g, t dbSNP:774543663
2242 2242 c, t dbSNP:759584837
2251 2251 a, c dbSNP:768750670
2272 2272 a, c dbSNP:775643582
2275 2275 c, g dbSNP:760496447
2278 2278 a, g dbSNP:763811664
2281 2281 c, t dbSNP:753733816
2297 2297 c, t dbSNP:761868527
2315 2315 a, g dbSNP:104894355
2326 2326 c, t dbSNP:138936640
2327 2327 g, t dbSNP:113994117
2328 2328 c, t dbSNP:104894352
2329 2329 a, g dbSNP:142055425
2332 2332 a, c dbSNP:757958737
2346 2346 g, t dbSNP:113994118
2354 2354 c, t dbSNP:104894358
2363 2363 -, gagggggaa dbSNP:771334337
2374 2374 -, ctc dbSNP:774708491
2377 2377 -, gg dbSNP:759982414
2384 2384 a, t dbSNP:779873859
2385 2385 a, t dbSNP:751215384
2392 2392 a, c, t dbSNP:756549028
2393 2393 a, g dbSNP:749598869
2401 2401 c, g dbSNP:76066681
2402 2402 c, g dbSNP:532197467
2408 2408 g, t dbSNP:745972916
2425 2425 a, c dbSNP:182735896
2432 2432 c, g dbSNP:150849316
2433 2433 a, g dbSNP:139383685
2438 2438 a, g dbSNP:768749436
2452 2452 a, g dbSNP:112561866
2454 2454 a, g dbSNP:761482576
2458 2458 a, g dbSNP:765269318
2459 2459 c, t dbSNP:773233842
2463 2463 a, g dbSNP:762582185
2473 2473 a, g dbSNP:765917230
2476 2476 c, g dbSNP:751268531
2483 2483 a, g dbSNP:754731331
2487 2487 c, t dbSNP:767068909
2488 2488 a, g dbSNP:754282438
2505 2505 a, g dbSNP:368829607
2507 2507 c, t dbSNP:548263208
2509 2509 c, t dbSNP:746310475
2510 2510 a, g dbSNP:758488049
2516 2516 a, g, t dbSNP:780167432
2518 2518 c, t dbSNP:768963686
2520 2520 a, g dbSNP:150612442
2522 2522 a, g dbSNP:747996470
2525 2525 a, g dbSNP:139646303
2543 2543 a, g dbSNP:769434101
2545 2545 a, t dbSNP:4766309
2554 2554 a, t dbSNP:372539672
2561 2561 c, g dbSNP:766403463
2563 2563 c, t dbSNP:376380409
2564 2564 a, t dbSNP:758933813
2566 2566 c, t dbSNP:199969874
2569 2569 a, g dbSNP:147828649
2576 2576 c, t dbSNP:199901819
2583 2583 a, c dbSNP:757648784
2584 2584 a, c dbSNP:765530769
2602 2602 a, g dbSNP:4766310
2607 2607 a, g dbSNP:202073663
2609 2609 a, g dbSNP:540037560
2612 2612 c, t dbSNP:747141780
2633 2633 c, t dbSNP:754962797
2637 2637 a, g dbSNP:781506153
2643 2643 a, t dbSNP:748250708
2644 2644 -, a dbSNP:767865722
2644 2644 a, t dbSNP:769642056
2676 2676 a, g dbSNP:145091423
2682 2682 c, t dbSNP:554160763
2695 2695 g, t dbSNP:546908339
2702 2702 a, g dbSNP:567053967
2718 2718 c, t dbSNP:11063404
2720 2720 a, c dbSNP:116918891
2736 2736 a, g dbSNP:555794044
2744 2744 a, g dbSNP:760230132
2754 2754 g, t dbSNP:575237307
2782 2782 a, g dbSNP:187069793
2796 2796 -, taaac dbSNP:771733057
2821 2821 a, c dbSNP:142908193
2830 2830 g, t dbSNP:751744254
2834 2834 -, gagt dbSNP:754775770
2905 2905 a, t dbSNP:41276726
2964 2964 a, c dbSNP:576763480
2975 2975 a, g dbSNP:765998332
2999 2999 c, t dbSNP:4766311
3021 3021 a, t dbSNP:759077382
3035 3035 a, g dbSNP:146156288
3068 3068 a, g dbSNP:781376867
3070 3070 a, g dbSNP:192177179
3079 3079 c, g dbSNP:764863360
3103 3103 c, g dbSNP:752092379
3110 3110 c, t dbSNP:140164407
3121 3121 c, t dbSNP:561717077
3135 3135 g, t dbSNP:546866157
3165 3165 a, g dbSNP:530539705
3173 3173 a, g dbSNP:757881150
3185 3185 a, c dbSNP:144000949
3195 3195 c, t dbSNP:564054015
3226 3226 a, g dbSNP:545243809
3304 3304 c, t dbSNP:533503353
3316 3316 c, t dbSNP:146431395
3338 3338 a, g dbSNP:752717989
3347 3347 a, g dbSNP:767771916
3372 3372 a, g dbSNP:566961688
3374 3374 a, t dbSNP:536000760
3379 3379 a, g dbSNP:148607588
3400 3400 a, g dbSNP:370895427
3422 3422 a, g dbSNP:777685914
3424 3424 c, t dbSNP:537934478
3442 3442 a, g dbSNP:41276728
3458 3458 c, t dbSNP:185131733
3476 3476 g, t dbSNP:756451969
3495 3495 c, t dbSNP:780278287
3516 3516 c, t dbSNP:142134789
3540 3540 c, t dbSNP:557429239
3560 3560 c, t dbSNP:539390362
3585 3585 c, g dbSNP:779002153
3613 3613 a, g dbSNP:188341851
3618 3618 g, t dbSNP:748072136
3641 3641 a, g dbSNP:151168223
3733 3733 g, t dbSNP:375198507
3764 3764 a, t dbSNP:541980109
3774 3774 a, g dbSNP:527940866
3783 3783 a, t dbSNP:561780718
3812 3812 a, g dbSNP:112825988
3813 3813 c, t dbSNP:749035499
3880 3880 a, g dbSNP:373978199
3901 3901 c, t dbSNP:575443810
3913 3913 a, c dbSNP:544323143
3920 3920 a, c, t dbSNP:564111472
3935 3935 a, g dbSNP:773036389
4006 4006 a, g dbSNP:78304820
4023 4023 a, g dbSNP:193300365
4036 4036 -, caaa dbSNP:556392591
4037 4037 -, caaa dbSNP:138257860
4040 4040 -, caaa dbSNP:765227866
4062 4062 a, g dbSNP:536746031
4097 4097 a, g dbSNP:770664473
4115 4115 c, g dbSNP:140297443
4117 4117 a, g dbSNP:79357862
4136 4136 c, g dbSNP:769400004
4170 4170 a, t dbSNP:79432803
4274 4274 c, t dbSNP:7974459
4293 4293 a, t dbSNP:531736702
4299 4299 a, g dbSNP:551448904
4315 4315 a, g dbSNP:768015077
4374 4374 g, t dbSNP:750920375
4416 4416 a, g dbSNP:748710312
4428 4428 c, t dbSNP:375487768
4436 4436 g, t dbSNP:185478426
4485 4485 c, t dbSNP:146972463
4505 4505 a, c dbSNP:553013502
4518 4518 a, g dbSNP:779439223
4520 4520 a, t dbSNP:7974559
4555 4555 c, t dbSNP:535731106
4598 4598 a, g dbSNP:76783799
4630 4630 a, c dbSNP:532350310
4664 4664 c, t dbSNP:11063405
4666 4666 c, t dbSNP:575501949
4673 4673 a, g dbSNP:147644839
4695 4695 c, t dbSNP:778949051
4701 4701 c, t dbSNP:752715296
4714 4714 c, t dbSNP:188295490
4716 4716 a, g dbSNP:77647135
4739 4739 c, t dbSNP:763240144
4740 4740 a, g dbSNP:540193617
4756 4756 c, g dbSNP:180733846
4767 4767 c, t dbSNP:73050551
4772 4772 c, t dbSNP:746944336
4811 4811 a, t dbSNP:542909255
4812 4812 a, g dbSNP:562779828
4838 4838 c, g dbSNP:76258625
4865 4865 -, cc dbSNP:36035195
4865 4865 a, c dbSNP:368591903
4866 4866 -, c dbSNP:540683822
4870 4870 -, cc dbSNP:397724146
4871 4871 c, t dbSNP:551461158
4879 4879 a, c dbSNP:759796830
4901 4901 c, g dbSNP:114342545
4906 4906 c, t dbSNP:183989674
4926 4926 a, g dbSNP:2109420
4933 4933 a, g dbSNP:567529801
4961 4961 c, t dbSNP:535790092
4962 4962 a, g dbSNP:529867699
5009 5009 a, c dbSNP:373448819
5016 5016 c, t dbSNP:775299403
5036 5036 c, t dbSNP:762490576
5055 5055 c, g dbSNP:530153989
5081 5081 c, t dbSNP:376503311
5147 5147 c, t dbSNP:768068963
5174 5174 a, t dbSNP:200499946
5189 5189 a, t dbSNP:188377239
5249 5249 c, t dbSNP:538010485
5284 5284 c, t dbSNP:557586316
5291 5291 a, g dbSNP:577704432
5302 5302 c, t dbSNP:539932572
5304 5304 c, t dbSNP:761122980
5320 5320 c, t dbSNP:113371270
5326 5326 c, t dbSNP:756191315
5327 5327 a, g dbSNP:115244229
5403 5403 c, t dbSNP:542921545
5441 5441 a, g dbSNP:562792530
5442 5442 c, t dbSNP:576248126
5443 5443 a, g dbSNP:763945925
5466 5466 c, t dbSNP:753755008
5467 5467 g, t dbSNP:545162947
5476 5476 c, t dbSNP:565320844
5517 5517 a, t dbSNP:146125116
5542 5542 a, g dbSNP:757025781
5580 5580 a, g dbSNP:547570693
5593 5593 a, g dbSNP:759905728
5598 5598 a, g dbSNP:765376770
5604 5604 g, t dbSNP:561344869
5644 5644 a, g dbSNP:112092813
5650 5650 a, g dbSNP:549320011
5655 5655 c, t dbSNP:10849174
5676 5676 g, t dbSNP:538124999
5756 5756 a, g dbSNP:758456685
5769 5769 a, g dbSNP:181233186
5797 5797 a, t dbSNP:571352674
5818 5818 a, c, g dbSNP:777765225
5933 5933 a, t dbSNP:757211402
6024 6024 c, g dbSNP:373024452
6029 6029 c, t dbSNP:553545136
6081 6081 g, t dbSNP:759574230
6096 6096 c, t dbSNP:532649581
6109 6109 a, g dbSNP:552881321
6110 6110 a, g dbSNP:767555761
6123 6123 a, c dbSNP:745560718
6168 6168 a, c dbSNP:573302963
6181 6181 c, t dbSNP:535813845
6219 6219 c, t dbSNP:187158474
6317 6317 c, t dbSNP:73050554
6341 6341 c, g dbSNP:377228947
6343 6343 a, g dbSNP:565519193
6369 6369 a, g, t dbSNP:745605017
6433 6433 a, g dbSNP:148103166
6450 6450 g, t dbSNP:541519377
6455 6455 c, t dbSNP:746524947
6506 6506 -, t dbSNP:537084658
6509 6509 a, g dbSNP:561340259
6533 6533 -, t dbSNP:764194860
6541 6541 a, g dbSNP:768152318
6547 6547 c, g dbSNP:530132908
6563 6563 c, t dbSNP:765086812
6580 6580 a, c dbSNP:146113688
6583 6583 c, t dbSNP:563653916
6644 6644 c, t dbSNP:531686384
6664 6664 -, ag dbSNP:751084528
6679 6679 a, g dbSNP:551378340
6684 6684 c, t dbSNP:750170843
6691 6691 a, g dbSNP:571427273
6711 6711 c, t dbSNP:533700901
6714 6714 -, tac dbSNP:200787388
6724 6724 c, t dbSNP:779800271
6801 6801 a, g dbSNP:547489314
6806 6806 a, g dbSNP:557073369
6813 6813 g, t dbSNP:567342939
6827 6827 a, g dbSNP:61907267
6828 6828 a, t dbSNP:377736650
6832 6832 g, t dbSNP:371412343
6855 6855 c, t dbSNP:142281940
6867 6867 a, g dbSNP:749760679
6886 6886 c, g dbSNP:555768483
6887 6887 a, g dbSNP:575627884
6900 6900 a, c dbSNP:768178529
6908 6908 a, g dbSNP:539359233
6925 6925 c, t dbSNP:78340550
7032 7032 c, t dbSNP:12424292
7053 7053 g, t dbSNP:747536108
7070 7070 a, g dbSNP:191491257
7102 7102 -, a dbSNP:780945447
7106 7106 c, t dbSNP:544962624
7184 7184 g, t dbSNP:150901962
7228 7228 c, g dbSNP:1045892
7256 7256 a, g dbSNP:186319441
7266 7266 c, g dbSNP:543934248
7281 7281 a, g dbSNP:765612524
7292 7292 g, t dbSNP:563715370
7295 7295 a, t dbSNP:767851298
7302 7302 g, t dbSNP:532360370
7332 7332 c, t dbSNP:575527417
7334 7334 c, t dbSNP:775790134
7361 7361 c, t dbSNP:780834906
7373 7373 a, c dbSNP:763126407
7403 7403 c, t dbSNP:545289240
7420 7420 c, t dbSNP:139487158
7444 7444 a, c dbSNP:542191369
7467 7467 g, t dbSNP:544566349
7496 7496 c, g dbSNP:760686126
7522 7522 g, t dbSNP:751650934
7536 7536 c, t dbSNP:547311366
7541 7541 a, c dbSNP:567102071
7549 7549 c, g dbSNP:529784058
7550 7550 a, c dbSNP:549454829
7611 7611 g, t dbSNP:569313930
7626 7626 a, g dbSNP:538229627
7638 7638 c, g dbSNP:767499146
7640 7640 a, t dbSNP:748729762
7703 7703 c, t dbSNP:149653837
7726 7726 -, a dbSNP:753752185
7730 7730 a, c dbSNP:566279760
7734 7734 a, g dbSNP:41482147
7738 7738 c, t dbSNP:11063406
7784 7784 a, g dbSNP:575078827
7798 7798 c, t dbSNP:780031417
7802 7802 c, t dbSNP:189939908
7805 7805 c, t dbSNP:139521962
7841 7841 g, t dbSNP:577188603
7868 7868 g, t dbSNP:748959150
7879 7879 a, g dbSNP:754656859
7899 7899 c, t dbSNP:545841388
7949 7949 a, g dbSNP:559681728

Target ORF information:

RefSeq Version NM_000217
Organism Homo sapiens (human)
Definition Homo sapiens potassium channel, voltage gated shaker related subfamily A, member 1 (KCNA1), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1-C-(k)DYK
NM_000217

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
ATGACGGTGA TGTCTGGGGA GAACGTGGAC GAGGCTTCGG CCGCCCCGGG CCACCCCCAG 
GATGGCAGCT ACCCCCGGCA GGCCGACCAC GACGACCACG AGTGCTGCGA GCGCGTGGTG
ATCAACATCT CCGGGCTGCG CTTCGAGACG CAGCTCAAGA CCCTGGCGCA GTTCCCCAAC
ACGCTGCTGG GCAACCCTAA GAAACGCATG CGCTACTTCG ACCCCCTGAG GAACGAGTAC
TTCTTCGACC GCAACCGGCC CAGCTTCGAC GCCATCCTCT ACTACTACCA GTCCGGCGGC
CGCCTGCGGA GGCCGGTCAA CGTGCCCCTG GACATGTTCT CCGAGGAGAT CAAGTTTTAC
GAGTTGGGCG AGGAGGCCAT GGAGAAGTTC CGGGAGGACG AGGGCTTCAT CAAGGAGGAG
GAGCGCCCTC TGCCCGAGAA GGAGTACCAG CGCCAGGTGT GGCTGCTCTT CGAGTACCCC
GAGAGCTCGG GGCCCGCCAG GGTCATCGCC ATCGTCTCCG TCATGGTCAT CCTCATCTCC
ATCGTCATCT TTTGCCTGGA GACGCTCCCC GAGCTGAAGG ATGACAAGGA CTTCACGGGC
ACCGTCCACC GCATCGACAA CACCACGGTC ATCTACAATT CCAACATCTT CACAGACCCC
TTCTTCATCG TGGAAACGCT GTGTATCATC TGGTTCTCCT TCGAGCTGGT GGTGCGCTTC
TTCGCCTGCC CCAGCAAGAC GGACTTCTTC AAAAACATCA TGAACTTCAT AGACATTGTG
GCCATCATTC CTTATTTCAT CACGCTGGGC ACCGAGATAG CTGAGCAGGA AGGAAACCAG
AAGGGCGAGC AGGCCACCTC CCTGGCCATC CTCAGGGTCA TCCGCTTGGT AAGGGTTTTT
AGAATCTTCA AGCTCTCCCG CCACTCTAAG GGCCTCCAGA TCCTGGGCCA GACCCTCAAA
GCTAGTATGA GAGAGCTAGG GCTGCTCATC TTTTTCCTCT TCATCGGGGT CATCCTGTTT
TCTAGTGCAG TGTACTTTGC CGAGGCGGAA GAAGCTGAGT CGCACTTCTC CAGTATCCCC
GATGCTTTCT GGTGGGCGGT GGTGTCCATG ACCACTGTAG GATACGGTGA CATGTACCCT
GTGACAATTG GAGGCAAGAT CGTGGGCTCC TTGTGTGCCA TCGCTGGTGT GCTAACAATT
GCCCTGCCCG TACCTGTCAT TGTGTCCAAT TTCAACTATT TCTACCACCG AGAAACTGAG
GGGGAAGAGC AGGCTCAGTT GCTCCACGTC AGTTCCCCTA ACTTAGCCTC TGACAGTGAC
CTCAGTCGCC GCAGTTCCTC TACTATGAGC AAGTCTGAGT ACATGGAGAT CGAAGAGGAT
ATGAATAATA GCATAGCCCA TTATAGACAG GTCAATATCA GAACTGCCAA TTGCACCACT
GCTAACCAAA ACTGCGTTAA TAAGAGCAAG CTACTGACCG ATGTTTAA

The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.