Email to GenScript

HSD11B1L hydroxysteroid (11-beta) dehydrogenase 1-like [Homo sapiens (human)]

Gene Symbol HSD11B1L
Entrez Gene ID 374875
Full Name hydroxysteroid (11-beta) dehydrogenase 1-like
Synonyms 11-DH3, 11-beta-HSD3, HSD3, SCDR10, SCDR10B, SDR26C2
General protein information
Preferred Names
hydroxysteroid 11-beta-dehydrogenase 1-like protein
Names
hydroxysteroid 11-beta-dehydrogenase 1-like protein
short chain dehydrogenase/reductase 10
11-beta-hydroxysteroid dehydrogenase type 3
short chain dehydrogenase/reductase family 26C, member 2
NP_001254797.1
NP_001254798.1
NP_001254799.1
NP_001254800.1
NP_940935.1
NP_941993.1
NP_941994.1
NP_941995.1
NP_941996.1
NP_941997.1
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

19

19p13.3

Summary This gene is a member of the hydroxysteroid dehydrogenase family. The encoded protein is similar to an enzyme that catalyzes the interconversion of inactive to active glucocorticoids (e.g. cortisone). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jun 2012]. lac of sum
Disorder MIM:

Disorder Html:





The following HSD11B1L gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the HSD11B1L gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu02665 NM_198705 Homo sapiens hydroxysteroid (11-beta) dehydrogenase 1-like (HSD11B1L), transcript variant a, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $269
OHu03629 NM_001267871 Homo sapiens hydroxysteroid (11-beta) dehydrogenase 1-like (HSD11B1L), transcript variant i, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $199
OHu02667 NM_198707 Homo sapiens hydroxysteroid (11-beta) dehydrogenase 1-like (HSD11B1L), transcript variant c, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $99
OHu02611 NM_198533 Homo sapiens hydroxysteroid (11-beta) dehydrogenase 1-like (HSD11B1L), transcript variant e, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $199
OHu02664 NM_198704 Homo sapiens hydroxysteroid (11-beta) dehydrogenase 1-like (HSD11B1L), transcript variant f, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $99
OHu11837 NM_001267868 Homo sapiens hydroxysteroid (11-beta) dehydrogenase 1-like (HSD11B1L), transcript variant g, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $319
OHu03628 NM_001267870 Homo sapiens hydroxysteroid (11-beta) dehydrogenase 1-like (HSD11B1L), transcript variant h, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $199
OHu02666 NM_198706 Homo sapiens hydroxysteroid (11-beta) dehydrogenase 1-like (HSD11B1L), transcript variant b, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $309
OHu02668 NM_198708 Homo sapiens hydroxysteroid (11-beta) dehydrogenase 1-like (HSD11B1L), transcript variant d, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$99
OHu02668 NM_001267869 Homo sapiens hydroxysteroid (11-beta) dehydrogenase 1-like (HSD11B1L), transcript variant j, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$99

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu02665
Accession Version NM_198705.2
Sequence Information ORF Nucleotide Sequence (Length: 618bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-APR-2015
Organism Homo sapiens (human)
Product hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform a precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA343367.1, AY268351.1 and AI871311.1. On Jun 26, 2012 this sequence version replaced gi:38424074. Summary: This gene is a member of the hydroxysteroid dehydrogenase family. The encoded protein is similar to an enzyme that catalyzes the interconversion of inactive to active glucocorticoids (e.g. cortisone). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jun 2012]. Transcript Variant: This variant (a) has multiple differences in the coding region, one of which results in initiation of translation at a downstream in-frame start codon, compared to variant g. The encoded protein (isoform a) is shorter than isoform g. ##Evidence-Data-START## Transcript exon combination :: AY268351.1, BM546973.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2142680 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
ATGAAGGTGC TTCTCCTCAC AGGGCTGGGG GCCCTGTTCT TCGCCTATTA TTGGGATGAC 
AACTTCGACC CAGGCGGGCT GGACTACCTC GTGCTGAACC ACATCGGCGG CGCCCCGGCC
GGCACGCGAG CCCGCAGCCC CCAGGCAACT CGCTGGCTCA TGCAGGTAAA CTTTGTGAGC
TACGTGCAAC TGACGTCGCG GGCGCTGCCC AGCCTGACGG ACAGCAAGGG CTCCCTGGTG
GTGGTGTCCT CGCTGCTCGG CCGCGTGCCC ACGTCGTTCT CCACTCCCTA CTCGGCGGCC
AAGTTTGCGC TGGACGGCTT CTTCGGCTCC CTGCGGCGGG AGCTGGACGT GCAGGACGTG
AACGTGGCCA TCACCATGTG CGTCCTGGGC CTCCGAGATC GCGCCTCCGC CGCCGAGGCA
GTCAGGGGAG TCACGAGGGT CAAGGCGGCC CCGGGGCCCA AGGCAGCCCT GGCCGTGATC
CGCGGCGGCG CCACGCGCGC GGCCGGCGTC TTCTACCCGT GGCGTTTCCG CCTGCTGTGC
TTGCTCCGGC GCTGGCTACC GCGCCCGCGG GCCTGGTTTA TCCGCCAGGA GCTCAACGTC
ACGGCCGCGG CAGCCTGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_941994.1
CDS522..1139
Misc Feature(1)501..503(+)
Misc Feature(2)594..1043(+)
Misc Feature(3)618..917(+)
Misc Feature(4)690..824(+)
Exon (1)1..507
Gene:HSD11B1L
Gene Synonym:
Exon (2)508..594
Gene:HSD11B1L
Gene Synonym:
Exon (3)595..686
Gene:HSD11B1L
Gene Synonym:
Exon (4)687..780
Gene:HSD11B1L
Gene Synonym:
Exon (5)781..946
Gene:HSD11B1L
Gene Synonym:
Exon (6)947..1717
Gene:HSD11B1L
Gene Synonym:
Translation
Position Chain Variation Link
9 9 a, g dbSNP:536571939
29 29 c, g dbSNP:374470108
36 36 c, g dbSNP:553183853
120 120 a, g dbSNP:368349880
214 214 a, g dbSNP:777133816
221 221 c, t dbSNP:572960614
222 222 c, g dbSNP:545227692
233 233 c, t dbSNP:564912252
278 278 c, g, t dbSNP:372389691
296 296 c, t dbSNP:547566141
301 301 a, g dbSNP:759306534
304 304 a, g dbSNP:375379743
330 330 c, g dbSNP:560575101
340 340 -, c dbSNP:34175618
353 353 a, g dbSNP:529595991
371 371 c, t dbSNP:369435874
394 394 a, g dbSNP:113651086
397 397 c, g dbSNP:371409148
461 461 a, g dbSNP:748861579
462 462 a, g dbSNP:540534380
475 475 c, g dbSNP:560881938
507 507 a, g dbSNP:770430936
514 514 a, c dbSNP:377450352
520 520 a, c dbSNP:754635706
521 521 c, t dbSNP:371137127
547 547 a, t dbSNP:752208098
551 551 a, g, t dbSNP:755580266
555 555 c, g dbSNP:749812625
563 563 c, t dbSNP:771610051
564 564 a, g dbSNP:761542737
571 571 a, g dbSNP:746243674
575 575 a, g dbSNP:772298551
581 581 a, c dbSNP:549857184
583 583 a, g dbSNP:760751212
587 587 c, t dbSNP:375620357
593 593 a, t dbSNP:151120147
597 597 a, g dbSNP:759058739
605 605 -, t dbSNP:746809651
626 626 a, c dbSNP:746940980
628 628 a, g dbSNP:768756023
629 629 a, c dbSNP:781111075
632 632 c, t dbSNP:747977283
641 641 c, t dbSNP:769291082
643 643 a, g dbSNP:772922135
649 649 a, g dbSNP:762308388
651 651 a, g dbSNP:770458522
656 656 a, c dbSNP:773914890
659 659 a, c dbSNP:760001903
668 668 a, g dbSNP:553392555
674 674 c, t dbSNP:768036784
693 693 -, tt dbSNP:769712221
695 695 g, t dbSNP:573835230
696 696 a, g dbSNP:150257776
697 697 a, t dbSNP:750489209
705 705 c, g dbSNP:758556104
710 710 a, g dbSNP:767503263
714 714 a, t dbSNP:752663568
715 715 c, t dbSNP:201073054
721 721 a, g dbSNP:756069021
730 730 c, g dbSNP:777591577
740 740 a, c, g, t dbSNP:749083432
748 748 a, g dbSNP:745328325
756 756 c, t dbSNP:557786197
760 760 c, t dbSNP:774930617
762 762 g, t dbSNP:747520012
765 765 c, g dbSNP:769094826
767 767 g, t dbSNP:777006347
768 768 g, t dbSNP:145508592
773 773 g, t dbSNP:770073014
776 776 a, g dbSNP:559436875
783 783 c, t dbSNP:200160626
785 785 c, t dbSNP:753709255
787 787 c, t dbSNP:373184843
791 791 c, g dbSNP:761810402
792 792 a, c dbSNP:764986364
796 796 c, t dbSNP:141267148
807 807 a, c dbSNP:757998904
812 812 c, t dbSNP:779606571
823 823 a, g dbSNP:751013061
824 824 a, g dbSNP:754458782
826 826 a, t dbSNP:146926014
829 829 c, t dbSNP:748660161
830 830 c, g dbSNP:770459446
836 836 c, t dbSNP:137877589
845 845 c, t dbSNP:749690063
854 854 a, g dbSNP:771141594
868 868 a, t dbSNP:774453035
874 874 a, g dbSNP:746162710
876 876 g, t dbSNP:772044493
888 888 -, c dbSNP:762294466
902 902 a, c dbSNP:775588057
915 915 c, g dbSNP:761716785
922 922 a, g dbSNP:765182780
928 928 a, c dbSNP:772953499
929 929 a, c dbSNP:762739987
930 930 -, c dbSNP:767936738
933 933 g, t dbSNP:546875772
935 935 c, t dbSNP:377447728
937 937 a, g dbSNP:751157788
940 940 c, t dbSNP:754725834
941 941 a, t dbSNP:370561561
942 942 c, g dbSNP:766902997
954 954 a, g dbSNP:773145526
956 956 a, g dbSNP:750820052
958 958 a, g dbSNP:559010746
970 970 -, c dbSNP:756753325
971 971 c, t dbSNP:533902103
975 975 c, g dbSNP:759084835
995 995 a, c dbSNP:569248499
996 996 a, g dbSNP:752211098
1011 1011 g, t dbSNP:755686967
1013 1013 -, ca dbSNP:766886344
1015 1015 -, cg dbSNP:752187047
1015 1015 c, g dbSNP:763757172
1022 1022 g, t dbSNP:537348427
1025 1025 c, g, t dbSNP:757826749
1026 1026 a, g, t dbSNP:557250916
1033 1033 c, t dbSNP:758509770
1039 1039 a, c dbSNP:780262061
1040 1040 g, t dbSNP:747031423
1044 1044 c, t dbSNP:768707595
1064 1064 c, g dbSNP:781314607
1080 1080 c, t dbSNP:749149020
1084 1084 c, g, t dbSNP:200586681
1085 1085 c, g, t dbSNP:759403823
1088 1088 c, g dbSNP:775270839
1097 1097 a, g dbSNP:780084584
1105 1105 a, g dbSNP:186351373
1124 1124 c, g dbSNP:755013240
1126 1126 c, t dbSNP:763669331
1129 1129 c, t dbSNP:753440628
1142 1142 a, c dbSNP:762177710
1146 1146 a, g dbSNP:765805593
1147 1147 a, g dbSNP:750688958
1148 1148 a, g dbSNP:552868043
1157 1157 -, a dbSNP:757885964
1160 1160 a, g dbSNP:201052217
1170 1170 a, g dbSNP:544743697
1171 1171 c, g dbSNP:368644338
1174 1174 a, t dbSNP:781227352
1182 1182 c, t dbSNP:748278231
1189 1189 a, c dbSNP:371623584
1218 1218 g, t dbSNP:373687274
1235 1235 a, g dbSNP:748051957
1267 1267 a, g dbSNP:771990238
1270 1270 a, c dbSNP:367791868
1278 1278 c, t dbSNP:190801974
1294 1294 c, t dbSNP:769857104
1297 1297 c, t dbSNP:752423341
1303 1303 a, c dbSNP:768445779
1309 1309 a, c dbSNP:530306798
1317 1317 a, g dbSNP:183044011
1320 1320 a, g dbSNP:761394201
1323 1323 g, t dbSNP:765607052
1333 1333 c, t dbSNP:566920318
1336 1336 a, g dbSNP:763515779
1351 1351 c, t dbSNP:766695241
1371 1371 c, t dbSNP:3760768
1374 1374 c, g dbSNP:751966512
1397 1397 a, t dbSNP:532663451
1460 1460 c, g dbSNP:552658327
1483 1483 c, g dbSNP:187571419
1484 1484 c, g dbSNP:113160292
1488 1488 c, t dbSNP:769777076
1538 1538 a, c dbSNP:569286407
1556 1556 a, g dbSNP:75765597
1561 1561 c, t dbSNP:554997634
1600 1600 g, t dbSNP:113690946
1602 1602 a, g dbSNP:567576698
1608 1608 a, g dbSNP:534011465
1648 1648 a, g dbSNP:11554339
1677 1677 c, g dbSNP:770771592
1711 1711 c, t dbSNP:374998691

Target ORF information:

RefSeq Version NM_198705
Organism Homo sapiens (human)
Definition Homo sapiens hydroxysteroid (11-beta) dehydrogenase 1-like (HSD11B1L), transcript variant a, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_198705

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
ATGAAGGTGC TTCTCCTCAC AGGGCTGGGG GCCCTGTTCT TCGCCTATTA TTGGGATGAC 
AACTTCGACC CAGGCGGGCT GGACTACCTC GTGCTGAACC ACATCGGCGG CGCCCCGGCC
GGCACGCGAG CCCGCAGCCC CCAGGCAACT CGCTGGCTCA TGCAGGTAAA CTTTGTGAGC
TACGTGCAAC TGACGTCGCG GGCGCTGCCC AGCCTGACGG ACAGCAAGGG CTCCCTGGTG
GTGGTGTCCT CGCTGCTCGG CCGCGTGCCC ACGTCGTTCT CCACTCCCTA CTCGGCGGCC
AAGTTTGCGC TGGACGGCTT CTTCGGCTCC CTGCGGCGGG AGCTGGACGT GCAGGACGTG
AACGTGGCCA TCACCATGTG CGTCCTGGGC CTCCGAGATC GCGCCTCCGC CGCCGAGGCA
GTCAGGGGAG TCACGAGGGT CAAGGCGGCC CCGGGGCCCA AGGCAGCCCT GGCCGTGATC
CGCGGCGGCG CCACGCGCGC GGCCGGCGTC TTCTACCCGT GGCGTTTCCG CCTGCTGTGC
TTGCTCCGGC GCTGGCTACC GCGCCCGCGG GCCTGGTTTA TCCGCCAGGA GCTCAACGTC
ACGGCCGCGG CAGCCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu03629
Accession Version NM_001267871.1
Sequence Information ORF Nucleotide Sequence (Length: 705bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-APR-2015
Organism Homo sapiens (human)
Product hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform i precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA343367.1, AY313896.1 and AI871311.1. Summary: This gene is a member of the hydroxysteroid dehydrogenase family. The encoded protein is similar to an enzyme that catalyzes the interconversion of inactive to active glucocorticoids (e.g. cortisone). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jun 2012]. Transcript Variant: This variant (i) has multiple differences in the coding region, one of which results in initiation of translation at a downstream in-frame start codon, compared to variant g. An additional difference results in a frameshift. The encoded protein (isoform i) has a distinct C-terminus and is shorter than isoform g. ##Evidence-Data-START## Transcript exon combination :: AY313896.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA962350 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
ATGAAGGTGC TTCTCCTCAC AGGGCTGGGG GCCCTGTTCT TCGCCTATTA TTGGGATGAC 
AACTTCGACC CAGGCGGGCT GGACTACCTC GTGCTGAACC ACATCGGCGG CGCCCCGGCC
GGCACGCGAG CCCGCAGCCC CCAGGCAACT CGCTGGCTCA TGCAGGTAAA CTTTGTGAGC
TACGTGCAAC TGACGTCGCG GGCGCTGCCC AGCCTGACGG ACAGCAAGGG CTCCCTGGTG
GTGGTGTCCT CGCTGCTCGG CCGCGTGCCC ACGTCGTTCT CCACTCCCTA CTCGGCGGCC
AAGTTTGCGC TGGACGGCTT CTTCGGCTCC CTGCGGCGGG AGCTGGACGT GCAGGACGTG
AACGTGGCCA TCACCATGTG CGTCCTGGGC CTCCGAGATC GCGCCTCCGC CGCCGAGGCA
GTCAGGAGCT CAACGTCACG GCCGCGGCAG CCTGAGCACC GGGGGGTGCC CCTCCAGTCC
CAGACGGCAA TGTTCCTCCC TCCAACTGTC CCTGGAGCCA GAACACTCAC AGAGACACCC
CTGAGAGGGT GGCCACAGCC CAAGATGAAG TCATCAAGAC AGAAAAGCAA AACCGAGAAA
AACGACGGGC ACCTGGAACC AGTCACGGCT TGGGAGGTGC AGGTGCCCCG TGTTAGGCGC
CTTTGTCGGG GACTTGCAAG GCCTCACCTG TTTGGCCATG ATTGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_001254800.1
CDS522..1226
Misc Feature(1)501..503(+)
Misc Feature(2)594..>965(+)
Misc Feature(3)618..917(+)
Misc Feature(4)690..824(+)
Exon (1)1..507
Gene:HSD11B1L
Gene Synonym:
Exon (2)508..594
Gene:HSD11B1L
Gene Synonym:
Exon (3)595..686
Gene:HSD11B1L
Gene Synonym:
Exon (4)687..780
Gene:HSD11B1L
Gene Synonym:
Exon (5)781..946
Gene:HSD11B1L
Gene Synonym:
Exon (6)947..1554
Gene:HSD11B1L
Gene Synonym:
Translation
Position Chain Variation Link
9 9 a, g dbSNP:536571939
29 29 c, g dbSNP:374470108
36 36 c, g dbSNP:553183853
120 120 a, g dbSNP:368349880
214 214 a, g dbSNP:777133816
221 221 c, t dbSNP:572960614
222 222 c, g dbSNP:545227692
233 233 c, t dbSNP:564912252
278 278 c, g, t dbSNP:372389691
296 296 c, t dbSNP:547566141
301 301 a, g dbSNP:759306534
304 304 a, g dbSNP:375379743
330 330 c, g dbSNP:560575101
340 340 -, c dbSNP:34175618
353 353 a, g dbSNP:529595991
371 371 c, t dbSNP:369435874
394 394 a, g dbSNP:113651086
397 397 c, g dbSNP:371409148
461 461 a, g dbSNP:748861579
462 462 a, g dbSNP:540534380
475 475 c, g dbSNP:560881938
507 507 a, g dbSNP:770430936
514 514 a, c dbSNP:377450352
520 520 a, c dbSNP:754635706
521 521 c, t dbSNP:371137127
547 547 a, t dbSNP:752208098
551 551 a, g, t dbSNP:755580266
555 555 c, g dbSNP:749812625
563 563 c, t dbSNP:771610051
564 564 a, g dbSNP:761542737
571 571 a, g dbSNP:746243674
575 575 a, g dbSNP:772298551
581 581 a, c dbSNP:549857184
583 583 a, g dbSNP:760751212
587 587 c, t dbSNP:375620357
593 593 a, t dbSNP:151120147
597 597 a, g dbSNP:759058739
605 605 -, t dbSNP:746809651
626 626 a, c dbSNP:746940980
628 628 a, g dbSNP:768756023
629 629 a, c dbSNP:781111075
632 632 c, t dbSNP:747977283
641 641 c, t dbSNP:769291082
643 643 a, g dbSNP:772922135
649 649 a, g dbSNP:762308388
651 651 a, g dbSNP:770458522
656 656 a, c dbSNP:773914890
659 659 a, c dbSNP:760001903
668 668 a, g dbSNP:553392555
674 674 c, t dbSNP:768036784
693 693 -, tt dbSNP:769712221
695 695 g, t dbSNP:573835230
696 696 a, g dbSNP:150257776
697 697 a, t dbSNP:750489209
705 705 c, g dbSNP:758556104
710 710 a, g dbSNP:767503263
714 714 a, t dbSNP:752663568
715 715 c, t dbSNP:201073054
721 721 a, g dbSNP:756069021
730 730 c, g dbSNP:777591577
740 740 a, c, g, t dbSNP:749083432
748 748 a, g dbSNP:745328325
756 756 c, t dbSNP:557786197
760 760 c, t dbSNP:774930617
762 762 g, t dbSNP:747520012
765 765 c, g dbSNP:769094826
767 767 g, t dbSNP:777006347
768 768 g, t dbSNP:145508592
773 773 g, t dbSNP:770073014
776 776 a, g dbSNP:559436875
783 783 c, t dbSNP:200160626
785 785 c, t dbSNP:753709255
787 787 c, t dbSNP:373184843
791 791 c, g dbSNP:761810402
792 792 a, c dbSNP:764986364
796 796 c, t dbSNP:141267148
807 807 a, c dbSNP:757998904
812 812 c, t dbSNP:779606571
823 823 a, g dbSNP:751013061
824 824 a, g dbSNP:754458782
826 826 a, t dbSNP:146926014
829 829 c, t dbSNP:748660161
830 830 c, g dbSNP:770459446
836 836 c, t dbSNP:137877589
845 845 c, t dbSNP:749690063
854 854 a, g dbSNP:771141594
868 868 a, t dbSNP:774453035
874 874 a, g dbSNP:746162710
876 876 g, t dbSNP:772044493
888 888 -, c dbSNP:762294466
902 902 a, c dbSNP:775588057
915 915 c, g dbSNP:761716785
922 922 a, g dbSNP:765182780
928 928 a, c dbSNP:772953499
929 929 a, c dbSNP:762739987
930 930 -, c dbSNP:767936738
933 933 g, t dbSNP:546875772
935 935 c, t dbSNP:377447728
937 937 a, g dbSNP:751157788
940 940 c, t dbSNP:754725834
941 941 a, t dbSNP:370561561
942 942 c, g dbSNP:766902997
961 961 c, g dbSNP:755013240
963 963 c, t dbSNP:763669331
966 966 c, t dbSNP:753440628
979 979 a, c dbSNP:762177710
983 983 a, g dbSNP:765805593
984 984 a, g dbSNP:750688958
985 985 a, g dbSNP:552868043
994 994 -, a dbSNP:757885964
997 997 a, g dbSNP:201052217
1007 1007 a, g dbSNP:544743697
1008 1008 c, g dbSNP:368644338
1011 1011 a, t dbSNP:781227352
1019 1019 c, t dbSNP:748278231
1026 1026 a, c dbSNP:371623584
1055 1055 g, t dbSNP:373687274
1072 1072 a, g dbSNP:748051957
1104 1104 a, g dbSNP:771990238
1107 1107 a, c dbSNP:367791868
1115 1115 c, t dbSNP:190801974
1131 1131 c, t dbSNP:769857104
1134 1134 c, t dbSNP:752423341
1140 1140 a, c dbSNP:768445779
1146 1146 a, c dbSNP:530306798
1154 1154 a, g dbSNP:183044011
1157 1157 a, g dbSNP:761394201
1160 1160 g, t dbSNP:765607052
1170 1170 c, t dbSNP:566920318
1173 1173 a, g dbSNP:763515779
1188 1188 c, t dbSNP:766695241
1208 1208 c, t dbSNP:3760768
1211 1211 c, g dbSNP:751966512
1234 1234 a, t dbSNP:532663451
1297 1297 c, g dbSNP:552658327
1320 1320 c, g dbSNP:187571419
1321 1321 c, g dbSNP:113160292
1325 1325 c, t dbSNP:769777076
1375 1375 a, c dbSNP:569286407
1393 1393 a, g dbSNP:75765597
1398 1398 c, t dbSNP:554997634
1437 1437 g, t dbSNP:113690946
1439 1439 a, g dbSNP:567576698
1445 1445 a, g dbSNP:534011465
1485 1485 a, g dbSNP:11554339
1514 1514 c, g dbSNP:770771592
1548 1548 c, t dbSNP:374998691

Target ORF information:

RefSeq Version NM_001267871
Organism Homo sapiens (human)
Definition Homo sapiens hydroxysteroid (11-beta) dehydrogenase 1-like (HSD11B1L), transcript variant i, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001267871

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
ATGAAGGTGC TTCTCCTCAC AGGGCTGGGG GCCCTGTTCT TCGCCTATTA TTGGGATGAC 
AACTTCGACC CAGGCGGGCT GGACTACCTC GTGCTGAACC ACATCGGCGG CGCCCCGGCC
GGCACGCGAG CCCGCAGCCC CCAGGCAACT CGCTGGCTCA TGCAGGTAAA CTTTGTGAGC
TACGTGCAAC TGACGTCGCG GGCGCTGCCC AGCCTGACGG ACAGCAAGGG CTCCCTGGTG
GTGGTGTCCT CGCTGCTCGG CCGCGTGCCC ACGTCGTTCT CCACTCCCTA CTCGGCGGCC
AAGTTTGCGC TGGACGGCTT CTTCGGCTCC CTGCGGCGGG AGCTGGACGT GCAGGACGTG
AACGTGGCCA TCACCATGTG CGTCCTGGGC CTCCGAGATC GCGCCTCCGC CGCCGAGGCA
GTCAGGAGCT CAACGTCACG GCCGCGGCAG CCTGAGCACC GGGGGGTGCC CCTCCAGTCC
CAGACGGCAA TGTTCCTCCC TCCAACTGTC CCTGGAGCCA GAACACTCAC AGAGACACCC
CTGAGAGGGT GGCCACAGCC CAAGATGAAG TCATCAAGAC AGAAAAGCAA AACCGAGAAA
AACGACGGGC ACCTGGAACC AGTCACGGCT TGGGAGGTGC AGGTGCCCCG TGTTAGGCGC
CTTTGTCGGG GACTTGCAAG GCCTCACCTG TTTGGCCATG ATTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu02667
Accession Version NM_198707.2
Sequence Information ORF Nucleotide Sequence (Length: 600bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-APR-2015
Organism Homo sapiens (human)
Product hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform c
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA343367.1, AY268353.1 and AI871311.1. On Jun 26, 2012 this sequence version replaced gi:38424078. Summary: This gene is a member of the hydroxysteroid dehydrogenase family. The encoded protein is similar to an enzyme that catalyzes the interconversion of inactive to active glucocorticoids (e.g. cortisone). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jun 2012]. Transcript Variant: This variant (c) lacks two exons and a portion of the 5' coding region, and initiates translation at a downstream in-frame start codon, compared to variant 1. The encoded isoform (c) is shorter than isoform g. ##Evidence-Data-START## Transcript exon combination :: AY268353.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2145245 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
ATGGCCTCCC CTGAGGCGCC CGAGAGCGTG GTGCAGTTTG CGCTGGACAA GCTGGGCGGG 
CTGGACTACC TCGTGCTGAA CCACATCGGC GGCGCCCCGG CCGGCACGCG AGCCCGCAGC
CCCCAGGCAA CTCGCTGGCT CATGCAGGTA AACTTTGTGA GCTACGTGCA ACTGACGTCG
CGGGCGCTGC CCAGCCTGAC GGACAGCAAG GGCTCCCTGG TGGTGGTGTC CTCGCTGCTC
GGCCGCGTGC CCACGTCGTT CTCCACTCCC TACTCGGCGG CCAAGTTTGC GCTGGACGGC
TTCTTCGGCT CCCTGCGGCG GGAGCTGGAC GTGCAGGACG TGAACGTGGC CATCACCATG
TGCGTCCTGG GCCTCCGAGA TCGCGCCTCC GCCGCCGAGG CAGTCAGGGG AGTCACGAGG
GTCAAGGCGG CCCCGGGGCC CAAGGCAGCC CTGGCCGTGA TCCGCGGCGG CGCCACGCGC
GCGGCCGGCG TCTTCTACCC GTGGCGTTTC CGCCTGCTGT GCTTGCTCCG GCGCTGGCTA
CCGCGCCCGC GGGCCTGGTT TATCCGCCAG GAGCTCAACG TCACGGCCGC GGCAGCCTGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_941996.1
CDS720..1319
Misc Feature(1)510..512(+)
Misc Feature(2)720..1223(+)
Misc Feature(3)798..1097(+)
Misc Feature(4)870..1004(+)
Exon (1)1..507
Gene:HSD11B1L
Gene Synonym:
Exon (2)508..662
Gene:HSD11B1L
Gene Synonym:
Exon (3)663..774
Gene:HSD11B1L
Gene Synonym:
Exon (4)775..866
Gene:HSD11B1L
Gene Synonym:
Exon (5)867..960
Gene:HSD11B1L
Gene Synonym:
Exon (6)961..1126
Gene:HSD11B1L
Gene Synonym:
Exon (7)1127..1897
Gene:HSD11B1L
Gene Synonym:
Translation
Position Chain Variation Link
9 9 a, g dbSNP:536571939
29 29 c, g dbSNP:374470108
36 36 c, g dbSNP:553183853
120 120 a, g dbSNP:368349880
214 214 a, g dbSNP:777133816
221 221 c, t dbSNP:572960614
222 222 c, g dbSNP:545227692
233 233 c, t dbSNP:564912252
278 278 c, g, t dbSNP:372389691
296 296 c, t dbSNP:547566141
301 301 a, g dbSNP:759306534
304 304 a, g dbSNP:375379743
330 330 c, g dbSNP:560575101
340 340 -, c dbSNP:34175618
353 353 a, g dbSNP:529595991
371 371 c, t dbSNP:369435874
394 394 a, g dbSNP:113651086
397 397 c, g dbSNP:371409148
461 461 a, g dbSNP:748861579
462 462 a, g dbSNP:540534380
475 475 c, g dbSNP:560881938
507 507 a, g dbSNP:770430936
516 516 a, c, t dbSNP:779595609
517 517 c, t dbSNP:372234338
519 519 -, c dbSNP:35181288
519 519 c, t dbSNP:762549635
520 520 a, g dbSNP:371417226
532 532 c, t dbSNP:768905891
542 542 a, g dbSNP:776668734
548 548 a, g dbSNP:748248147
549 549 c, g, t dbSNP:770811587
550 550 a, c, g dbSNP:759313781
563 563 -, ag dbSNP:768172247
568 568 c, t dbSNP:775398718
569 569 c, t dbSNP:760385158
571 571 a, g dbSNP:763863867
572 572 c, t dbSNP:753361319
573 573 a, g dbSNP:756833114
580 580 c, t dbSNP:765782828
582 582 -, gtga dbSNP:750912624
583 583 a, g dbSNP:148042659
601 601 a, c, g dbSNP:200835892
607 607 c, t dbSNP:780249226
608 608 a, g dbSNP:141021013
609 609 c, t dbSNP:535314623
610 610 c, g dbSNP:781422805
618 618 c, t dbSNP:748156322
626 626 a, g dbSNP:374641413
627 627 a, g dbSNP:765889177
668 668 a, g dbSNP:781519298
670 670 a, g dbSNP:780048368
671 671 c, g dbSNP:746744557
692 692 c, t dbSNP:768557969
701 701 a, c dbSNP:199995247
706 706 a, g dbSNP:776637614
713 713 c, g dbSNP:761527897
722 722 a, g dbSNP:528046422
728 728 c, g dbSNP:769533807
741 741 a, g dbSNP:551077796
763 763 c, t dbSNP:762554836
777 777 a, g dbSNP:759058739
785 785 -, t dbSNP:746809651
806 806 a, c dbSNP:746940980
808 808 a, g dbSNP:768756023
809 809 a, c dbSNP:781111075
812 812 c, t dbSNP:747977283
821 821 c, t dbSNP:769291082
823 823 a, g dbSNP:772922135
829 829 a, g dbSNP:762308388
831 831 a, g dbSNP:770458522
836 836 a, c dbSNP:773914890
839 839 a, c dbSNP:760001903
848 848 a, g dbSNP:553392555
854 854 c, t dbSNP:768036784
873 873 -, tt dbSNP:769712221
875 875 g, t dbSNP:573835230
876 876 a, g dbSNP:150257776
877 877 a, t dbSNP:750489209
885 885 c, g dbSNP:758556104
890 890 a, g dbSNP:767503263
894 894 a, t dbSNP:752663568
895 895 c, t dbSNP:201073054
901 901 a, g dbSNP:756069021
910 910 c, g dbSNP:777591577
920 920 a, c, g, t dbSNP:749083432
928 928 a, g dbSNP:745328325
936 936 c, t dbSNP:557786197
940 940 c, t dbSNP:774930617
942 942 g, t dbSNP:747520012
945 945 c, g dbSNP:769094826
947 947 g, t dbSNP:777006347
948 948 g, t dbSNP:145508592
953 953 g, t dbSNP:770073014
956 956 a, g dbSNP:559436875
963 963 c, t dbSNP:200160626
965 965 c, t dbSNP:753709255
967 967 c, t dbSNP:373184843
971 971 c, g dbSNP:761810402
972 972 a, c dbSNP:764986364
976 976 c, t dbSNP:141267148
987 987 a, c dbSNP:757998904
992 992 c, t dbSNP:779606571
1003 1003 a, g dbSNP:751013061
1004 1004 a, g dbSNP:754458782
1006 1006 a, t dbSNP:146926014
1009 1009 c, t dbSNP:748660161
1010 1010 c, g dbSNP:770459446
1016 1016 c, t dbSNP:137877589
1025 1025 c, t dbSNP:749690063
1034 1034 a, g dbSNP:771141594
1048 1048 a, t dbSNP:774453035
1054 1054 a, g dbSNP:746162710
1056 1056 g, t dbSNP:772044493
1068 1068 -, c dbSNP:762294466
1082 1082 a, c dbSNP:775588057
1095 1095 c, g dbSNP:761716785
1102 1102 a, g dbSNP:765182780
1108 1108 a, c dbSNP:772953499
1109 1109 a, c dbSNP:762739987
1110 1110 -, c dbSNP:767936738
1113 1113 g, t dbSNP:546875772
1115 1115 c, t dbSNP:377447728
1117 1117 a, g dbSNP:751157788
1120 1120 c, t dbSNP:754725834
1121 1121 a, t dbSNP:370561561
1122 1122 c, g dbSNP:766902997
1134 1134 a, g dbSNP:773145526
1136 1136 a, g dbSNP:750820052
1138 1138 a, g dbSNP:559010746
1150 1150 -, c dbSNP:756753325
1151 1151 c, t dbSNP:533902103
1155 1155 c, g dbSNP:759084835
1175 1175 a, c dbSNP:569248499
1176 1176 a, g dbSNP:752211098
1191 1191 g, t dbSNP:755686967
1193 1193 -, ca dbSNP:766886344
1195 1195 -, cg dbSNP:752187047
1195 1195 c, g dbSNP:763757172
1202 1202 g, t dbSNP:537348427
1205 1205 c, g, t dbSNP:757826749
1206 1206 a, g, t dbSNP:557250916
1213 1213 c, t dbSNP:758509770
1219 1219 a, c dbSNP:780262061
1220 1220 g, t dbSNP:747031423
1224 1224 c, t dbSNP:768707595
1244 1244 c, g dbSNP:781314607
1260 1260 c, t dbSNP:749149020
1264 1264 c, g, t dbSNP:200586681
1265 1265 c, g, t dbSNP:759403823
1268 1268 c, g dbSNP:775270839
1277 1277 a, g dbSNP:780084584
1285 1285 a, g dbSNP:186351373
1304 1304 c, g dbSNP:755013240
1306 1306 c, t dbSNP:763669331
1309 1309 c, t dbSNP:753440628
1322 1322 a, c dbSNP:762177710
1326 1326 a, g dbSNP:765805593
1327 1327 a, g dbSNP:750688958
1328 1328 a, g dbSNP:552868043
1337 1337 -, a dbSNP:757885964
1340 1340 a, g dbSNP:201052217
1350 1350 a, g dbSNP:544743697
1351 1351 c, g dbSNP:368644338
1354 1354 a, t dbSNP:781227352
1362 1362 c, t dbSNP:748278231
1369 1369 a, c dbSNP:371623584
1398 1398 g, t dbSNP:373687274
1415 1415 a, g dbSNP:748051957
1447 1447 a, g dbSNP:771990238
1450 1450 a, c dbSNP:367791868
1458 1458 c, t dbSNP:190801974
1474 1474 c, t dbSNP:769857104
1477 1477 c, t dbSNP:752423341
1483 1483 a, c dbSNP:768445779
1489 1489 a, c dbSNP:530306798
1497 1497 a, g dbSNP:183044011
1500 1500 a, g dbSNP:761394201
1503 1503 g, t dbSNP:765607052
1513 1513 c, t dbSNP:566920318
1516 1516 a, g dbSNP:763515779
1531 1531 c, t dbSNP:766695241
1551 1551 c, t dbSNP:3760768
1554 1554 c, g dbSNP:751966512
1577 1577 a, t dbSNP:532663451
1640 1640 c, g dbSNP:552658327
1663 1663 c, g dbSNP:187571419
1664 1664 c, g dbSNP:113160292
1668 1668 c, t dbSNP:769777076
1718 1718 a, c dbSNP:569286407
1736 1736 a, g dbSNP:75765597
1741 1741 c, t dbSNP:554997634
1780 1780 g, t dbSNP:113690946
1782 1782 a, g dbSNP:567576698
1788 1788 a, g dbSNP:534011465
1828 1828 a, g dbSNP:11554339
1857 1857 c, g dbSNP:770771592
1891 1891 c, t dbSNP:374998691

Target ORF information:

RefSeq Version NM_198707
Organism Homo sapiens (human)
Definition Homo sapiens hydroxysteroid (11-beta) dehydrogenase 1-like (HSD11B1L), transcript variant c, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_198707

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
ATGGCCTCCC CTGAGGCGCC CGAGAGCGTG GTGCAGTTTG CGCTGGACAA GCTGGGCGGG 
CTGGACTACC TCGTGCTGAA CCACATCGGC GGCGCCCCGG CCGGCACGCG AGCCCGCAGC
CCCCAGGCAA CTCGCTGGCT CATGCAGGTA AACTTTGTGA GCTACGTGCA ACTGACGTCG
CGGGCGCTGC CCAGCCTGAC GGACAGCAAG GGCTCCCTGG TGGTGGTGTC CTCGCTGCTC
GGCCGCGTGC CCACGTCGTT CTCCACTCCC TACTCGGCGG CCAAGTTTGC GCTGGACGGC
TTCTTCGGCT CCCTGCGGCG GGAGCTGGAC GTGCAGGACG TGAACGTGGC CATCACCATG
TGCGTCCTGG GCCTCCGAGA TCGCGCCTCC GCCGCCGAGG CAGTCAGGGG AGTCACGAGG
GTCAAGGCGG CCCCGGGGCC CAAGGCAGCC CTGGCCGTGA TCCGCGGCGG CGCCACGCGC
GCGGCCGGCG TCTTCTACCC GTGGCGTTTC CGCCTGCTGT GCTTGCTCCG GCGCTGGCTA
CCGCGCCCGC GGGCCTGGTT TATCCGCCAG GAGCTCAACG TCACGGCCGC GGCAGCCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu02611
Accession Version NM_198533.2
Sequence Information ORF Nucleotide Sequence (Length: 948bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-APR-2015
Organism Homo sapiens (human)
Product hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform e precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA343367.1, AY313894.1 and AI871311.1. On Jun 26, 2012 this sequence version replaced gi:38348361. Summary: This gene is a member of the hydroxysteroid dehydrogenase family. The encoded protein is similar to an enzyme that catalyzes the interconversion of inactive to active glucocorticoids (e.g. cortisone). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jun 2012]. Transcript Variant: This variant (e) lacks an exon and a portion of the 5' coding region, and initiates translation at a downstream in-frame start codon, compared to variant g. This variant (e) also uses an alternate splice site in the 3' coding region, which results in a frameshift. The encoded protein (isoform e) has a distinct C-terminus and is shorter than isoform g. ##Evidence-Data-START## Transcript exon combination :: AY313894.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968832, SAMEA962350 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGAAGGTGC TTCTCCTCAC AGGGCTGGGG GCCCTGTTCT TCGCCTATTA TTGGGATGAC 
AACTTCGACC CAGCCAGCCT CCAGGGAGCG CGAGTGCTGC TGACAGGGGC CAACGCTGGT
GTTGGTGAGG AGCTGGCCTA TCACTACGCG CGTCTGGGCT CCCACCTGGT GCTCACTGCC
CACACTGAGG CTCTCCTGCA GAAGGTGGTA GGGAACTGCC GGAAGCTGGG CGCCCCCAAG
GTCTTCTACA TCGCGGCGGA CATGGCCTCC CCTGAGGCGC CCGAGAGCGT GGTGCAGTTT
GCGCTGGACA AGCTGGGCGG GCTGGACTAC CTCGTGCTGA ACCACATCGG CGGCGCCCCG
GCCGGCACGC GAGCCCGCAG CCCCCAGGCA ACTCGCTGGC TCATGCAGGT AAACTTTGTG
AGCTACGTGC AACTGACGTC GCGGGCGCTG CCCAGCCTGA CGGACAGCAA GGGCTCCCTG
GTGGTGGTGT CCTCGCTGCT CGGCCGCGTG CCCACGTCGT TCTCCACTCC CTACTCGGCG
GCCAAGTTTG CGCTGGACGG CTTCTTCGGC TCCCTGCGGC GGGAGCTGGA CGTGCAGGAC
GTGAACGTGG CCATCACCAT GTGCGTCCTG GGCCTCCGAG ATCGCGCCTC CGCCGCCGAG
GCAGTCAGGA GCTCAACGTC ACGGCCGCGG CAGCCTGAGC ACCGGGGGGT GCCCCTCCAG
TCCCAGACGG CAATGTTCCT CCCTCCAACT GTCCCTGGAG CCAGAACACT CACAGAGACA
CCCCTGAGAG GGTGGCCACA GCCCAAGATG AAGTCATCAA GACAGAAAAG CAAAACCGAG
AAAAACGACG GGCACCTGGA ACCAGTCACG GCTTGGGAGG TGCAGGTGCC CCGTGTTAGG
CGCCTTTGTC GGGGACTTGC AAGGCCTCAC CTGTTTGGCC ATGATTGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_940935.1
CDS522..1469
Misc Feature(1)501..503(+)
Misc Feature(2)600..>1208(+)
Misc Feature(3)615..1109(+)
Misc Feature(4)627..1160(+)
Misc Feature(5)933..1067(+)
Exon (1)1..507
Gene:HSD11B1L
Gene Synonym:
Exon (2)508..594
Gene:HSD11B1L
Gene Synonym:
Exon (3)595..725
Gene:HSD11B1L
Gene Synonym:
Exon (4)726..837
Gene:HSD11B1L
Gene Synonym:
Exon (5)838..929
Gene:HSD11B1L
Gene Synonym:
Exon (6)930..1023
Gene:HSD11B1L
Gene Synonym:
Exon (7)1024..1189
Gene:HSD11B1L
Gene Synonym:
Exon (8)1190..1797
Gene:HSD11B1L
Gene Synonym:
Translation
Position Chain Variation Link
9 9 a, g dbSNP:536571939
29 29 c, g dbSNP:374470108
36 36 c, g dbSNP:553183853
120 120 a, g dbSNP:368349880
214 214 a, g dbSNP:777133816
221 221 c, t dbSNP:572960614
222 222 c, g dbSNP:545227692
233 233 c, t dbSNP:564912252
278 278 c, g, t dbSNP:372389691
296 296 c, t dbSNP:547566141
301 301 a, g dbSNP:759306534
304 304 a, g dbSNP:375379743
330 330 c, g dbSNP:560575101
340 340 -, c dbSNP:34175618
353 353 a, g dbSNP:529595991
371 371 c, t dbSNP:369435874
394 394 a, g dbSNP:113651086
397 397 c, g dbSNP:371409148
461 461 a, g dbSNP:748861579
462 462 a, g dbSNP:540534380
475 475 c, g dbSNP:560881938
507 507 a, g dbSNP:770430936
514 514 a, c dbSNP:377450352
520 520 a, c dbSNP:754635706
521 521 c, t dbSNP:371137127
547 547 a, t dbSNP:752208098
551 551 a, g, t dbSNP:755580266
555 555 c, g dbSNP:749812625
563 563 c, t dbSNP:771610051
564 564 a, g dbSNP:761542737
571 571 a, g dbSNP:746243674
575 575 a, g dbSNP:772298551
581 581 a, c dbSNP:549857184
583 583 a, g dbSNP:760751212
587 587 c, t dbSNP:375620357
593 593 a, t dbSNP:151120147
595 595 c, t dbSNP:768905891
605 605 a, g dbSNP:776668734
611 611 a, g dbSNP:748248147
612 612 c, g, t dbSNP:770811587
613 613 a, c, g dbSNP:759313781
626 626 -, ag dbSNP:768172247
631 631 c, t dbSNP:775398718
632 632 c, t dbSNP:760385158
634 634 a, g dbSNP:763863867
635 635 c, t dbSNP:753361319
636 636 a, g dbSNP:756833114
643 643 c, t dbSNP:765782828
645 645 -, gtga dbSNP:750912624
646 646 a, g dbSNP:148042659
664 664 a, c, g dbSNP:200835892
670 670 c, t dbSNP:780249226
671 671 a, g dbSNP:141021013
672 672 c, t dbSNP:535314623
673 673 c, g dbSNP:781422805
681 681 c, t dbSNP:748156322
689 689 a, g dbSNP:374641413
690 690 a, g dbSNP:765889177
731 731 a, g dbSNP:781519298
733 733 a, g dbSNP:780048368
734 734 c, g dbSNP:746744557
755 755 c, t dbSNP:768557969
764 764 a, c dbSNP:199995247
769 769 a, g dbSNP:776637614
776 776 c, g dbSNP:761527897
785 785 a, g dbSNP:528046422
791 791 c, g dbSNP:769533807
804 804 a, g dbSNP:551077796
826 826 c, t dbSNP:762554836
840 840 a, g dbSNP:759058739
848 848 -, t dbSNP:746809651
869 869 a, c dbSNP:746940980
871 871 a, g dbSNP:768756023
872 872 a, c dbSNP:781111075
875 875 c, t dbSNP:747977283
884 884 c, t dbSNP:769291082
886 886 a, g dbSNP:772922135
892 892 a, g dbSNP:762308388
894 894 a, g dbSNP:770458522
899 899 a, c dbSNP:773914890
902 902 a, c dbSNP:760001903
911 911 a, g dbSNP:553392555
917 917 c, t dbSNP:768036784
936 936 -, tt dbSNP:769712221
938 938 g, t dbSNP:573835230
939 939 a, g dbSNP:150257776
940 940 a, t dbSNP:750489209
948 948 c, g dbSNP:758556104
953 953 a, g dbSNP:767503263
957 957 a, t dbSNP:752663568
958 958 c, t dbSNP:201073054
964 964 a, g dbSNP:756069021
973 973 c, g dbSNP:777591577
983 983 a, c, g, t dbSNP:749083432
991 991 a, g dbSNP:745328325
999 999 c, t dbSNP:557786197
1003 1003 c, t dbSNP:774930617
1005 1005 g, t dbSNP:747520012
1008 1008 c, g dbSNP:769094826
1010 1010 g, t dbSNP:777006347
1011 1011 g, t dbSNP:145508592
1016 1016 g, t dbSNP:770073014
1019 1019 a, g dbSNP:559436875
1026 1026 c, t dbSNP:200160626
1028 1028 c, t dbSNP:753709255
1030 1030 c, t dbSNP:373184843
1034 1034 c, g dbSNP:761810402
1035 1035 a, c dbSNP:764986364
1039 1039 c, t dbSNP:141267148
1050 1050 a, c dbSNP:757998904
1055 1055 c, t dbSNP:779606571
1066 1066 a, g dbSNP:751013061
1067 1067 a, g dbSNP:754458782
1069 1069 a, t dbSNP:146926014
1072 1072 c, t dbSNP:748660161
1073 1073 c, g dbSNP:770459446
1079 1079 c, t dbSNP:137877589
1088 1088 c, t dbSNP:749690063
1097 1097 a, g dbSNP:771141594
1111 1111 a, t dbSNP:774453035
1117 1117 a, g dbSNP:746162710
1119 1119 g, t dbSNP:772044493
1131 1131 -, c dbSNP:762294466
1145 1145 a, c dbSNP:775588057
1158 1158 c, g dbSNP:761716785
1165 1165 a, g dbSNP:765182780
1171 1171 a, c dbSNP:772953499
1172 1172 a, c dbSNP:762739987
1173 1173 -, c dbSNP:767936738
1176 1176 g, t dbSNP:546875772
1178 1178 c, t dbSNP:377447728
1180 1180 a, g dbSNP:751157788
1183 1183 c, t dbSNP:754725834
1184 1184 a, t dbSNP:370561561
1185 1185 c, g dbSNP:766902997
1204 1204 c, g dbSNP:755013240
1206 1206 c, t dbSNP:763669331
1209 1209 c, t dbSNP:753440628
1222 1222 a, c dbSNP:762177710
1226 1226 a, g dbSNP:765805593
1227 1227 a, g dbSNP:750688958
1228 1228 a, g dbSNP:552868043
1237 1237 -, a dbSNP:757885964
1240 1240 a, g dbSNP:201052217
1250 1250 a, g dbSNP:544743697
1251 1251 c, g dbSNP:368644338
1254 1254 a, t dbSNP:781227352
1262 1262 c, t dbSNP:748278231
1269 1269 a, c dbSNP:371623584
1298 1298 g, t dbSNP:373687274
1315 1315 a, g dbSNP:748051957
1347 1347 a, g dbSNP:771990238
1350 1350 a, c dbSNP:367791868
1358 1358 c, t dbSNP:190801974
1374 1374 c, t dbSNP:769857104
1377 1377 c, t dbSNP:752423341
1383 1383 a, c dbSNP:768445779
1389 1389 a, c dbSNP:530306798
1397 1397 a, g dbSNP:183044011
1400 1400 a, g dbSNP:761394201
1403 1403 g, t dbSNP:765607052
1413 1413 c, t dbSNP:566920318
1416 1416 a, g dbSNP:763515779
1431 1431 c, t dbSNP:766695241
1451 1451 c, t dbSNP:3760768
1454 1454 c, g dbSNP:751966512
1477 1477 a, t dbSNP:532663451
1540 1540 c, g dbSNP:552658327
1563 1563 c, g dbSNP:187571419
1564 1564 c, g dbSNP:113160292
1568 1568 c, t dbSNP:769777076
1618 1618 a, c dbSNP:569286407
1636 1636 a, g dbSNP:75765597
1641 1641 c, t dbSNP:554997634
1680 1680 g, t dbSNP:113690946
1682 1682 a, g dbSNP:567576698
1688 1688 a, g dbSNP:534011465
1728 1728 a, g dbSNP:11554339
1757 1757 c, g dbSNP:770771592
1791 1791 c, t dbSNP:374998691

Target ORF information:

RefSeq Version NM_198533
Organism Homo sapiens (human)
Definition Homo sapiens hydroxysteroid (11-beta) dehydrogenase 1-like (HSD11B1L), transcript variant e, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_198533

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGAAGGTGC TTCTCCTCAC AGGGCTGGGG GCCCTGTTCT TCGCCTATTA TTGGGATGAC 
AACTTCGACC CAGCCAGCCT CCAGGGAGCG CGAGTGCTGC TGACAGGGGC CAACGCTGGT
GTTGGTGAGG AGCTGGCCTA TCACTACGCG CGTCTGGGCT CCCACCTGGT GCTCACTGCC
CACACTGAGG CTCTCCTGCA GAAGGTGGTA GGGAACTGCC GGAAGCTGGG CGCCCCCAAG
GTCTTCTACA TCGCGGCGGA CATGGCCTCC CCTGAGGCGC CCGAGAGCGT GGTGCAGTTT
GCGCTGGACA AGCTGGGCGG GCTGGACTAC CTCGTGCTGA ACCACATCGG CGGCGCCCCG
GCCGGCACGC GAGCCCGCAG CCCCCAGGCA ACTCGCTGGC TCATGCAGGT AAACTTTGTG
AGCTACGTGC AACTGACGTC GCGGGCGCTG CCCAGCCTGA CGGACAGCAA GGGCTCCCTG
GTGGTGGTGT CCTCGCTGCT CGGCCGCGTG CCCACGTCGT TCTCCACTCC CTACTCGGCG
GCCAAGTTTG CGCTGGACGG CTTCTTCGGC TCCCTGCGGC GGGAGCTGGA CGTGCAGGAC
GTGAACGTGG CCATCACCAT GTGCGTCCTG GGCCTCCGAG ATCGCGCCTC CGCCGCCGAG
GCAGTCAGGA GCTCAACGTC ACGGCCGCGG CAGCCTGAGC ACCGGGGGGT GCCCCTCCAG
TCCCAGACGG CAATGTTCCT CCCTCCAACT GTCCCTGGAG CCAGAACACT CACAGAGACA
CCCCTGAGAG GGTGGCCACA GCCCAAGATG AAGTCATCAA GACAGAAAAG CAAAACCGAG
AAAAACGACG GGCACCTGGA ACCAGTCACG GCTTGGGAGG TGCAGGTGCC CCGTGTTAGG
CGCCTTTGTC GGGGACTTGC AAGGCCTCAC CTGTTTGGCC ATGATTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu02664
Accession Version NM_198704.2
Sequence Information ORF Nucleotide Sequence (Length: 546bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-APR-2015
Organism Homo sapiens (human)
Product hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform f
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA343367.1, AY313895.1 and AI871311.1. On Jun 26, 2012 this sequence version replaced gi:38424080. Summary: This gene is a member of the hydroxysteroid dehydrogenase family. The encoded protein is similar to an enzyme that catalyzes the interconversion of inactive to active glucocorticoids (e.g. cortisone). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jun 2012]. Transcript Variant: This variant (f) has multiple differences in the coding region, one of which results in initiation of translation at a downstream in-frame start codon, compared to variant g. An additional difference results in a frameshift. The encoded protein (isoform f) has a distinct C-terminus and is shorter than isoform g. ##Evidence-Data-START## Transcript exon combination :: AY313895.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA962350 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
ATGCAGGTAA ACTTTGTGAG CTACGTGCAA CTGACGTCGC GGGCGCTGCC CAGCCTGACG 
GACAGCAAGG GCTCCCTGGT GGTGGTGTCC TCGCTGCTCG GCCGCGTGCC CACGTCGTTC
TCCACTCCCT ACTCGGCGGC CAAGTTTGCG CTGGACGGCT TCTTCGGCTC CCTGCGGCGG
GAGCTGGACG TGCAGGACGT GAACGTGGCC ATCACCATGT GCGTCCTGGG CCTCCGAGAT
CGCGCCTCCG CCGCCGAGGC AGTCAGGAGC TCAACGTCAC GGCCGCGGCA GCCTGAGCAC
CGGGGGGTGC CCCTCCAGTC CCAGACGGCA ATGTTCCTCC CTCCAACTGT CCCTGGAGCC
AGAACACTCA CAGAGACACC CCTGAGAGGG TGGCCACAGC CCAAGATGAA GTCATCAAGA
CAGAAAAGCA AAACCGAGAA AAACGACGGG CACCTGGAAC CAGTCACGGC TTGGGAGGTG
CAGGTGCCCC GTGTTAGGCG CCTTTGTCGG GGACTTGCAA GGCCTCACCT GTTTGGCCAT
GATTGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_941993.1
CDS749..1294
Misc Feature(1)644..646(+)
Misc Feature(2)749..>1033(+)
Misc Feature(3)758..892(+)
Exon (1)1..507
Gene:HSD11B1L
Gene Synonym:
Exon (2)508..662
Gene:HSD11B1L
Gene Synonym:
Exon (3)663..754
Gene:HSD11B1L
Gene Synonym:
Exon (4)755..848
Gene:HSD11B1L
Gene Synonym:
Exon (5)849..1014
Gene:HSD11B1L
Gene Synonym:
Exon (6)1015..1622
Gene:HSD11B1L
Gene Synonym:
Translation
Position Chain Variation Link
9 9 a, g dbSNP:536571939
29 29 c, g dbSNP:374470108
36 36 c, g dbSNP:553183853
120 120 a, g dbSNP:368349880
214 214 a, g dbSNP:777133816
221 221 c, t dbSNP:572960614
222 222 c, g dbSNP:545227692
233 233 c, t dbSNP:564912252
278 278 c, g, t dbSNP:372389691
296 296 c, t dbSNP:547566141
301 301 a, g dbSNP:759306534
304 304 a, g dbSNP:375379743
330 330 c, g dbSNP:560575101
340 340 -, c dbSNP:34175618
353 353 a, g dbSNP:529595991
371 371 c, t dbSNP:369435874
394 394 a, g dbSNP:113651086
397 397 c, g dbSNP:371409148
461 461 a, g dbSNP:748861579
462 462 a, g dbSNP:540534380
475 475 c, g dbSNP:560881938
507 507 a, g dbSNP:770430936
516 516 a, c, t dbSNP:779595609
517 517 c, t dbSNP:372234338
519 519 -, c dbSNP:35181288
519 519 c, t dbSNP:762549635
520 520 a, g dbSNP:371417226
532 532 c, t dbSNP:768905891
542 542 a, g dbSNP:776668734
548 548 a, g dbSNP:748248147
549 549 c, g, t dbSNP:770811587
550 550 a, c, g dbSNP:759313781
563 563 -, ag dbSNP:768172247
568 568 c, t dbSNP:775398718
569 569 c, t dbSNP:760385158
571 571 a, g dbSNP:763863867
572 572 c, t dbSNP:753361319
573 573 a, g dbSNP:756833114
580 580 c, t dbSNP:765782828
582 582 -, gtga dbSNP:750912624
583 583 a, g dbSNP:148042659
601 601 a, c, g dbSNP:200835892
607 607 c, t dbSNP:780249226
608 608 a, g dbSNP:141021013
609 609 c, t dbSNP:535314623
610 610 c, g dbSNP:781422805
618 618 c, t dbSNP:748156322
626 626 a, g dbSNP:374641413
627 627 a, g dbSNP:765889177
665 665 a, g dbSNP:759058739
673 673 -, t dbSNP:746809651
694 694 a, c dbSNP:746940980
696 696 a, g dbSNP:768756023
697 697 a, c dbSNP:781111075
700 700 c, t dbSNP:747977283
709 709 c, t dbSNP:769291082
711 711 a, g dbSNP:772922135
717 717 a, g dbSNP:762308388
719 719 a, g dbSNP:770458522
724 724 a, c dbSNP:773914890
727 727 a, c dbSNP:760001903
736 736 a, g dbSNP:553392555
742 742 c, t dbSNP:768036784
761 761 -, tt dbSNP:769712221
763 763 g, t dbSNP:573835230
764 764 a, g dbSNP:150257776
765 765 a, t dbSNP:750489209
773 773 c, g dbSNP:758556104
778 778 a, g dbSNP:767503263
782 782 a, t dbSNP:752663568
783 783 c, t dbSNP:201073054
789 789 a, g dbSNP:756069021
798 798 c, g dbSNP:777591577
808 808 a, c, g, t dbSNP:749083432
816 816 a, g dbSNP:745328325
824 824 c, t dbSNP:557786197
828 828 c, t dbSNP:774930617
830 830 g, t dbSNP:747520012
833 833 c, g dbSNP:769094826
835 835 g, t dbSNP:777006347
836 836 g, t dbSNP:145508592
841 841 g, t dbSNP:770073014
844 844 a, g dbSNP:559436875
851 851 c, t dbSNP:200160626
853 853 c, t dbSNP:753709255
855 855 c, t dbSNP:373184843
859 859 c, g dbSNP:761810402
860 860 a, c dbSNP:764986364
864 864 c, t dbSNP:141267148
875 875 a, c dbSNP:757998904
880 880 c, t dbSNP:779606571
891 891 a, g dbSNP:751013061
892 892 a, g dbSNP:754458782
894 894 a, t dbSNP:146926014
897 897 c, t dbSNP:748660161
898 898 c, g dbSNP:770459446
904 904 c, t dbSNP:137877589
913 913 c, t dbSNP:749690063
922 922 a, g dbSNP:771141594
936 936 a, t dbSNP:774453035
942 942 a, g dbSNP:746162710
944 944 g, t dbSNP:772044493
956 956 -, c dbSNP:762294466
970 970 a, c dbSNP:775588057
983 983 c, g dbSNP:761716785
990 990 a, g dbSNP:765182780
996 996 a, c dbSNP:772953499
997 997 a, c dbSNP:762739987
998 998 -, c dbSNP:767936738
1001 1001 g, t dbSNP:546875772
1003 1003 c, t dbSNP:377447728
1005 1005 a, g dbSNP:751157788
1008 1008 c, t dbSNP:754725834
1009 1009 a, t dbSNP:370561561
1010 1010 c, g dbSNP:766902997
1029 1029 c, g dbSNP:755013240
1031 1031 c, t dbSNP:763669331
1034 1034 c, t dbSNP:753440628
1047 1047 a, c dbSNP:762177710
1051 1051 a, g dbSNP:765805593
1052 1052 a, g dbSNP:750688958
1053 1053 a, g dbSNP:552868043
1062 1062 -, a dbSNP:757885964
1065 1065 a, g dbSNP:201052217
1075 1075 a, g dbSNP:544743697
1076 1076 c, g dbSNP:368644338
1079 1079 a, t dbSNP:781227352
1087 1087 c, t dbSNP:748278231
1094 1094 a, c dbSNP:371623584
1123 1123 g, t dbSNP:373687274
1140 1140 a, g dbSNP:748051957
1172 1172 a, g dbSNP:771990238
1175 1175 a, c dbSNP:367791868
1183 1183 c, t dbSNP:190801974
1199 1199 c, t dbSNP:769857104
1202 1202 c, t dbSNP:752423341
1208 1208 a, c dbSNP:768445779
1214 1214 a, c dbSNP:530306798
1222 1222 a, g dbSNP:183044011
1225 1225 a, g dbSNP:761394201
1228 1228 g, t dbSNP:765607052
1238 1238 c, t dbSNP:566920318
1241 1241 a, g dbSNP:763515779
1256 1256 c, t dbSNP:766695241
1276 1276 c, t dbSNP:3760768
1279 1279 c, g dbSNP:751966512
1302 1302 a, t dbSNP:532663451
1365 1365 c, g dbSNP:552658327
1388 1388 c, g dbSNP:187571419
1389 1389 c, g dbSNP:113160292
1393 1393 c, t dbSNP:769777076
1443 1443 a, c dbSNP:569286407
1461 1461 a, g dbSNP:75765597
1466 1466 c, t dbSNP:554997634
1505 1505 g, t dbSNP:113690946
1507 1507 a, g dbSNP:567576698
1513 1513 a, g dbSNP:534011465
1553 1553 a, g dbSNP:11554339
1582 1582 c, g dbSNP:770771592
1616 1616 c, t dbSNP:374998691

Target ORF information:

RefSeq Version NM_198704
Organism Homo sapiens (human)
Definition Homo sapiens hydroxysteroid (11-beta) dehydrogenase 1-like (HSD11B1L), transcript variant f, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_198704

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
ATGCAGGTAA ACTTTGTGAG CTACGTGCAA CTGACGTCGC GGGCGCTGCC CAGCCTGACG 
GACAGCAAGG GCTCCCTGGT GGTGGTGTCC TCGCTGCTCG GCCGCGTGCC CACGTCGTTC
TCCACTCCCT ACTCGGCGGC CAAGTTTGCG CTGGACGGCT TCTTCGGCTC CCTGCGGCGG
GAGCTGGACG TGCAGGACGT GAACGTGGCC ATCACCATGT GCGTCCTGGG CCTCCGAGAT
CGCGCCTCCG CCGCCGAGGC AGTCAGGAGC TCAACGTCAC GGCCGCGGCA GCCTGAGCAC
CGGGGGGTGC CCCTCCAGTC CCAGACGGCA ATGTTCCTCC CTCCAACTGT CCCTGGAGCC
AGAACACTCA CAGAGACACC CCTGAGAGGG TGGCCACAGC CCAAGATGAA GTCATCAAGA
CAGAAAAGCA AAACCGAGAA AAACGACGGG CACCTGGAAC CAGTCACGGC TTGGGAGGTG
CAGGTGCCCC GTGTTAGGCG CCTTTGTCGG GGACTTGCAA GGCCTCACCT GTTTGGCCAT
GATTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu11837
Accession Version NM_001267868.1
Sequence Information ORF Nucleotide Sequence (Length: 1002bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-APR-2015
Organism Homo sapiens (human)
Product hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform g
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA343367.1, AK308206.1, AC011499.5 and AI871311.1. Summary: This gene is a member of the hydroxysteroid dehydrogenase family. The encoded protein is similar to an enzyme that catalyzes the interconversion of inactive to active glucocorticoids (e.g. cortisone). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jun 2012]. Transcript Variant: This variant (g) represents the longest transcript and the longest protein (isoform g). ##Evidence-Data-START## Transcript exon combination :: AK308206.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2148093, SAMEA2151741 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGGCAAATC TCGGCACACT ACAACTTCTG CCTCCCAGGT TCAAGCGATT CTCCTGCCTC 
AGCCTCCCAA ATATCTGGAT TACAGGCATG CCTGTGCCGG CCACCTCTGT CCCCTGTCCC
TCTGCAGGCC CACACAGGAC CATGAAGGTG CTTCTCCTCA CAGGGCTGGG GGCCCTGTTC
TTCGCCTATT ATTGGGATGA CAACTTCGAC CCAGCCAGCC TCCAGGGAGC GCGAGTGCTG
CTGACAGGGG CCAACGCTGG TGTTGGTGAG GAGCTGGCCT ATCACTACGC GCGTCTGGGC
TCCCACCTGG TGCTCACTGC CCACACTGAG GCTCTCCTGC AGAAGGTGGT AGGGAACTGC
CGGAAGCTGG GCGCCCCCAA GGTCTTCTAC ATCGCGGCGG ACATGGCCTC CCCTGAGGCG
CCCGAGAGCG TGGTGCAGTT TGCGCTGGAC AAGCTGGGCG GGCTGGACTA CCTCGTGCTG
AACCACATCG GCGGCGCCCC GGCCGGCACG CGAGCCCGCA GCCCCCAGGC AACTCGCTGG
CTCATGCAGG TAAACTTTGT GAGCTACGTG CAACTGACGT CGCGGGCGCT GCCCAGCCTG
ACGGACAGCA AGGGCTCCCT GGTGGTGGTG TCCTCGCTGC TCGGCCGCGT GCCCACGTCG
TTCTCCACTC CCTACTCGGC GGCCAAGTTT GCGCTGGACG GCTTCTTCGG CTCCCTGCGG
CGGGAGCTGG ACGTGCAGGA CGTGAACGTG GCCATCACCA TGTGCGTCCT GGGCCTCCGA
GATCGCGCCT CCGCCGCCGA GGCAGTCAGG GGAGTCACGA GGGTCAAGGC GGCCCCGGGG
CCCAAGGCAG CCCTGGCCGT GATCCGCGGC GGCGCCACGC GCGCGGCCGG CGTCTTCTAC
CCGTGGCGTT TCCGCCTGCT GTGCTTGCTC CGGCGCTGGC TACCGCGCCC GCGGGCCTGG
TTTATCCGCC AGGAGCTCAA CGTCACGGCC GCGGCAGCCT GA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_001254797.1
CDS519..1520
Misc Feature(1)501..503(+)
Misc Feature(2)525..>596(+)
Misc Feature(3)738..1424(+)
Misc Feature(4)753..1247(+)
Misc Feature(5)765..1298(+)
Misc Feature(6)1071..1205(+)
Exon (1)1..507
Gene:HSD11B1L
Gene Synonym:
Exon (2)508..607
Gene:HSD11B1L
Gene Synonym:
Exon (3)608..732
Gene:HSD11B1L
Gene Synonym:
Exon (4)733..863
Gene:HSD11B1L
Gene Synonym:
Exon (5)864..975
Gene:HSD11B1L
Gene Synonym:
Exon (6)976..1067
Gene:HSD11B1L
Gene Synonym:
Exon (7)1068..1161
Gene:HSD11B1L
Gene Synonym:
Exon (8)1162..1327
Gene:HSD11B1L
Gene Synonym:
Exon (9)1328..2098
Gene:HSD11B1L
Gene Synonym:
Translation
Position Chain Variation Link
9 9 a, g dbSNP:536571939
29 29 c, g dbSNP:374470108
36 36 c, g dbSNP:553183853
120 120 a, g dbSNP:368349880
214 214 a, g dbSNP:777133816
221 221 c, t dbSNP:572960614
222 222 c, g dbSNP:545227692
233 233 c, t dbSNP:564912252
278 278 c, g, t dbSNP:372389691
296 296 c, t dbSNP:547566141
301 301 a, g dbSNP:759306534
304 304 a, g dbSNP:375379743
330 330 c, g dbSNP:560575101
340 340 -, c dbSNP:34175618
353 353 a, g dbSNP:529595991
371 371 c, t dbSNP:369435874
394 394 a, g dbSNP:113651086
397 397 c, g dbSNP:371409148
461 461 a, g dbSNP:748861579
462 462 a, g dbSNP:540534380
475 475 c, g dbSNP:560881938
507 507 a, g dbSNP:770430936
509 509 c, t dbSNP:766664199
552 552 c, g dbSNP:561611358
563 563 a, g dbSNP:774716236
609 609 c, t dbSNP:778451769
613 613 c, t dbSNP:749594957
616 616 c, t dbSNP:771411995
617 617 a, g dbSNP:774927067
621 621 -, a dbSNP:764367237
622 622 c, t dbSNP:759775326
623 623 c, t dbSNP:772234669
627 627 g, t dbSNP:775592702
632 632 -, ct dbSNP:751921472
634 634 c, g dbSNP:373146169
635 635 a, t dbSNP:765155296
636 636 c, t dbSNP:776558350
639 639 a, c, t dbSNP:762934945
652 652 a, c dbSNP:377450352
658 658 a, c dbSNP:754635706
659 659 c, t dbSNP:371137127
685 685 a, t dbSNP:752208098
689 689 a, g, t dbSNP:755580266
693 693 c, g dbSNP:749812625
701 701 c, t dbSNP:771610051
702 702 a, g dbSNP:761542737
709 709 a, g dbSNP:746243674
713 713 a, g dbSNP:772298551
719 719 a, c dbSNP:549857184
721 721 a, g dbSNP:760751212
725 725 c, t dbSNP:375620357
731 731 a, t dbSNP:151120147
733 733 c, t dbSNP:768905891
743 743 a, g dbSNP:776668734
749 749 a, g dbSNP:748248147
750 750 c, g, t dbSNP:770811587
751 751 a, c, g dbSNP:759313781
764 764 -, ag dbSNP:768172247
769 769 c, t dbSNP:775398718
770 770 c, t dbSNP:760385158
772 772 a, g dbSNP:763863867
773 773 c, t dbSNP:753361319
774 774 a, g dbSNP:756833114
781 781 c, t dbSNP:765782828
783 783 -, gtga dbSNP:750912624
784 784 a, g dbSNP:148042659
802 802 a, c, g dbSNP:200835892
808 808 c, t dbSNP:780249226
809 809 a, g dbSNP:141021013
810 810 c, t dbSNP:535314623
811 811 c, g dbSNP:781422805
819 819 c, t dbSNP:748156322
827 827 a, g dbSNP:374641413
828 828 a, g dbSNP:765889177
869 869 a, g dbSNP:781519298
871 871 a, g dbSNP:780048368
872 872 c, g dbSNP:746744557
893 893 c, t dbSNP:768557969
902 902 a, c dbSNP:199995247
907 907 a, g dbSNP:776637614
914 914 c, g dbSNP:761527897
923 923 a, g dbSNP:528046422
929 929 c, g dbSNP:769533807
942 942 a, g dbSNP:551077796
964 964 c, t dbSNP:762554836
978 978 a, g dbSNP:759058739
986 986 -, t dbSNP:746809651
1007 1007 a, c dbSNP:746940980
1009 1009 a, g dbSNP:768756023
1010 1010 a, c dbSNP:781111075
1013 1013 c, t dbSNP:747977283
1022 1022 c, t dbSNP:769291082
1024 1024 a, g dbSNP:772922135
1030 1030 a, g dbSNP:762308388
1032 1032 a, g dbSNP:770458522
1037 1037 a, c dbSNP:773914890
1040 1040 a, c dbSNP:760001903
1049 1049 a, g dbSNP:553392555
1055 1055 c, t dbSNP:768036784
1074 1074 -, tt dbSNP:769712221
1076 1076 g, t dbSNP:573835230
1077 1077 a, g dbSNP:150257776
1078 1078 a, t dbSNP:750489209
1086 1086 c, g dbSNP:758556104
1091 1091 a, g dbSNP:767503263
1095 1095 a, t dbSNP:752663568
1096 1096 c, t dbSNP:201073054
1102 1102 a, g dbSNP:756069021
1111 1111 c, g dbSNP:777591577
1121 1121 a, c, g, t dbSNP:749083432
1129 1129 a, g dbSNP:745328325
1137 1137 c, t dbSNP:557786197
1141 1141 c, t dbSNP:774930617
1143 1143 g, t dbSNP:747520012
1146 1146 c, g dbSNP:769094826
1148 1148 g, t dbSNP:777006347
1149 1149 g, t dbSNP:145508592
1154 1154 g, t dbSNP:770073014
1157 1157 a, g dbSNP:559436875
1164 1164 c, t dbSNP:200160626
1166 1166 c, t dbSNP:753709255
1168 1168 c, t dbSNP:373184843
1172 1172 c, g dbSNP:761810402
1173 1173 a, c dbSNP:764986364
1177 1177 c, t dbSNP:141267148
1188 1188 a, c dbSNP:757998904
1193 1193 c, t dbSNP:779606571
1204 1204 a, g dbSNP:751013061
1205 1205 a, g dbSNP:754458782
1207 1207 a, t dbSNP:146926014
1210 1210 c, t dbSNP:748660161
1211 1211 c, g dbSNP:770459446
1217 1217 c, t dbSNP:137877589
1226 1226 c, t dbSNP:749690063
1235 1235 a, g dbSNP:771141594
1249 1249 a, t dbSNP:774453035
1255 1255 a, g dbSNP:746162710
1257 1257 g, t dbSNP:772044493
1269 1269 -, c dbSNP:762294466
1283 1283 a, c dbSNP:775588057
1296 1296 c, g dbSNP:761716785
1303 1303 a, g dbSNP:765182780
1309 1309 a, c dbSNP:772953499
1310 1310 a, c dbSNP:762739987
1311 1311 -, c dbSNP:767936738
1314 1314 g, t dbSNP:546875772
1316 1316 c, t dbSNP:377447728
1318 1318 a, g dbSNP:751157788
1321 1321 c, t dbSNP:754725834
1322 1322 a, t dbSNP:370561561
1323 1323 c, g dbSNP:766902997
1335 1335 a, g dbSNP:773145526
1337 1337 a, g dbSNP:750820052
1339 1339 a, g dbSNP:559010746
1351 1351 -, c dbSNP:756753325
1352 1352 c, t dbSNP:533902103
1356 1356 c, g dbSNP:759084835
1376 1376 a, c dbSNP:569248499
1377 1377 a, g dbSNP:752211098
1392 1392 g, t dbSNP:755686967
1394 1394 -, ca dbSNP:766886344
1396 1396 -, cg dbSNP:752187047
1396 1396 c, g dbSNP:763757172
1403 1403 g, t dbSNP:537348427
1406 1406 c, g, t dbSNP:757826749
1407 1407 a, g, t dbSNP:557250916
1414 1414 c, t dbSNP:758509770
1420 1420 a, c dbSNP:780262061
1421 1421 g, t dbSNP:747031423
1425 1425 c, t dbSNP:768707595
1445 1445 c, g dbSNP:781314607
1461 1461 c, t dbSNP:749149020
1465 1465 c, g, t dbSNP:200586681
1466 1466 c, g, t dbSNP:759403823
1469 1469 c, g dbSNP:775270839
1478 1478 a, g dbSNP:780084584
1486 1486 a, g dbSNP:186351373
1505 1505 c, g dbSNP:755013240
1507 1507 c, t dbSNP:763669331
1510 1510 c, t dbSNP:753440628
1523 1523 a, c dbSNP:762177710
1527 1527 a, g dbSNP:765805593
1528 1528 a, g dbSNP:750688958
1529 1529 a, g dbSNP:552868043
1538 1538 -, a dbSNP:757885964
1541 1541 a, g dbSNP:201052217
1551 1551 a, g dbSNP:544743697
1552 1552 c, g dbSNP:368644338
1555 1555 a, t dbSNP:781227352
1563 1563 c, t dbSNP:748278231
1570 1570 a, c dbSNP:371623584
1599 1599 g, t dbSNP:373687274
1616 1616 a, g dbSNP:748051957
1648 1648 a, g dbSNP:771990238
1651 1651 a, c dbSNP:367791868
1659 1659 c, t dbSNP:190801974
1675 1675 c, t dbSNP:769857104
1678 1678 c, t dbSNP:752423341
1684 1684 a, c dbSNP:768445779
1690 1690 a, c dbSNP:530306798
1698 1698 a, g dbSNP:183044011
1701 1701 a, g dbSNP:761394201
1704 1704 g, t dbSNP:765607052
1714 1714 c, t dbSNP:566920318
1717 1717 a, g dbSNP:763515779
1732 1732 c, t dbSNP:766695241
1752 1752 c, t dbSNP:3760768
1755 1755 c, g dbSNP:751966512
1778 1778 a, t dbSNP:532663451
1841 1841 c, g dbSNP:552658327
1864 1864 c, g dbSNP:187571419
1865 1865 c, g dbSNP:113160292
1869 1869 c, t dbSNP:769777076
1919 1919 a, c dbSNP:569286407
1937 1937 a, g dbSNP:75765597
1942 1942 c, t dbSNP:554997634
1981 1981 g, t dbSNP:113690946
1983 1983 a, g dbSNP:567576698
1989 1989 a, g dbSNP:534011465
2029 2029 a, g dbSNP:11554339
2058 2058 c, g dbSNP:770771592
2092 2092 c, t dbSNP:374998691

Target ORF information:

RefSeq Version NM_001267868
Organism Homo sapiens (human)
Definition Homo sapiens hydroxysteroid (11-beta) dehydrogenase 1-like (HSD11B1L), transcript variant g, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001267868

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGGCAAATC TCGGCACACT ACAACTTCTG CCTCCCAGGT TCAAGCGATT CTCCTGCCTC 
AGCCTCCCAA ATATCTGGAT TACAGGCATG CCTGTGCCGG CCACCTCTGT CCCCTGTCCC
TCTGCAGGCC CACACAGGAC CATGAAGGTG CTTCTCCTCA CAGGGCTGGG GGCCCTGTTC
TTCGCCTATT ATTGGGATGA CAACTTCGAC CCAGCCAGCC TCCAGGGAGC GCGAGTGCTG
CTGACAGGGG CCAACGCTGG TGTTGGTGAG GAGCTGGCCT ATCACTACGC GCGTCTGGGC
TCCCACCTGG TGCTCACTGC CCACACTGAG GCTCTCCTGC AGAAGGTGGT AGGGAACTGC
CGGAAGCTGG GCGCCCCCAA GGTCTTCTAC ATCGCGGCGG ACATGGCCTC CCCTGAGGCG
CCCGAGAGCG TGGTGCAGTT TGCGCTGGAC AAGCTGGGCG GGCTGGACTA CCTCGTGCTG
AACCACATCG GCGGCGCCCC GGCCGGCACG CGAGCCCGCA GCCCCCAGGC AACTCGCTGG
CTCATGCAGG TAAACTTTGT GAGCTACGTG CAACTGACGT CGCGGGCGCT GCCCAGCCTG
ACGGACAGCA AGGGCTCCCT GGTGGTGGTG TCCTCGCTGC TCGGCCGCGT GCCCACGTCG
TTCTCCACTC CCTACTCGGC GGCCAAGTTT GCGCTGGACG GCTTCTTCGG CTCCCTGCGG
CGGGAGCTGG ACGTGCAGGA CGTGAACGTG GCCATCACCA TGTGCGTCCT GGGCCTCCGA
GATCGCGCCT CCGCCGCCGA GGCAGTCAGG GGAGTCACGA GGGTCAAGGC GGCCCCGGGG
CCCAAGGCAG CCCTGGCCGT GATCCGCGGC GGCGCCACGC GCGCGGCCGG CGTCTTCTAC
CCGTGGCGTT TCCGCCTGCT GTGCTTGCTC CGGCGCTGGC TACCGCGCCC GCGGGCCTGG
TTTATCCGCC AGGAGCTCAA CGTCACGGCC GCGGCAGCCT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu03628
Accession Version NM_001267870.1
Sequence Information ORF Nucleotide Sequence (Length: 615bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-APR-2015
Organism Homo sapiens (human)
Product hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform h precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA343367.1, CX865680.1, AY313894.1 and AI871311.1. Summary: This gene is a member of the hydroxysteroid dehydrogenase family. The encoded protein is similar to an enzyme that catalyzes the interconversion of inactive to active glucocorticoids (e.g. cortisone). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jun 2012]. Transcript Variant: This variant (h) has multiple differences in the coding region, one of which results in initiation of translation at a downstream in-frame start codon, compared to variant g. An additional difference results in a frameshift. The encoded protein (isoform h) has a distinct C-terminus and is shorter than isoform g. ##Evidence-Data-START## Transcript exon combination :: CX865680.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA962337 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
ATGAAGGTGC TTCTCCTCAC AGGGCTGGGG GCCCTGTTCT TCGCCTATTA TTGGGATGAC 
AACTTCGACC CAGGTAAACT TTGTGAGCTA CGTGCAACTG ACGTCGCGGG CGCTGCCCAG
CCTGACGGAC AGCAAGGGCT CCCTGGTGGT GGTGTCCTCG CTGCTCGGCC GCGTGCCCAC
GTCGTTCTCC ACTCCCTACT CGGCGGCCAA GTTTGCGCTG GACGGCTTCT TCGGCTCCCT
GCGGCGGGAG CTGGACGTGC AGGACGTGAA CGTGGCCATC ACCATGTGCG TCCTGGGCCT
CCGAGATCGC GCCTCCGCCG CCGAGGCAGT CAGGGGAGTC ACGAGGGTCA AGGCGGCCCC
GGGGCCCAAG GCAGCCCTGG CCGTGATCCG CGGCGGCGCC ACGCGCGCGG CCGGCGTCTT
CTACCCGTGG CGTTTCCGCC TGCTGTGCTT GCTCCGGCGC TGGCTACCGC GCCCGCGGGC
CTGGTTTATC CGCCAGGAGC TCAACGTCAC GGCCGCGGCA GCCTGAGCAC CGGGGGGTGC
CCCTCCAGTC CCAGACGGCA ATGTTCCTCC CTCCAACTGT CCCTGGAGCC AGAACACTCA
CAGAGACACC CCTGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_001254799.1
CDS522..1136
Misc Feature(1)501..503(+)
Exon (1)1..507
Gene:HSD11B1L
Gene Synonym:
Exon (2)508..594
Gene:HSD11B1L
Gene Synonym:
Exon (3)595..688
Gene:HSD11B1L
Gene Synonym:
Exon (4)689..854
Gene:HSD11B1L
Gene Synonym:
Exon (5)855..1625
Gene:HSD11B1L
Gene Synonym:
Translation
Position Chain Variation Link
9 9 a, g dbSNP:536571939
29 29 c, g dbSNP:374470108
36 36 c, g dbSNP:553183853
120 120 a, g dbSNP:368349880
214 214 a, g dbSNP:777133816
221 221 c, t dbSNP:572960614
222 222 c, g dbSNP:545227692
233 233 c, t dbSNP:564912252
278 278 c, g, t dbSNP:372389691
296 296 c, t dbSNP:547566141
301 301 a, g dbSNP:759306534
304 304 a, g dbSNP:375379743
330 330 c, g dbSNP:560575101
340 340 -, c dbSNP:34175618
353 353 a, g dbSNP:529595991
371 371 c, t dbSNP:369435874
394 394 a, g dbSNP:113651086
397 397 c, g dbSNP:371409148
461 461 a, g dbSNP:748861579
462 462 a, g dbSNP:540534380
475 475 c, g dbSNP:560881938
507 507 a, g dbSNP:770430936
514 514 a, c dbSNP:377450352
520 520 a, c dbSNP:754635706
521 521 c, t dbSNP:371137127
547 547 a, t dbSNP:752208098
551 551 a, g, t dbSNP:755580266
555 555 c, g dbSNP:749812625
563 563 c, t dbSNP:771610051
564 564 a, g dbSNP:761542737
571 571 a, g dbSNP:746243674
575 575 a, g dbSNP:772298551
581 581 a, c dbSNP:549857184
583 583 a, g dbSNP:760751212
587 587 c, t dbSNP:375620357
593 593 a, t dbSNP:151120147
601 601 -, tt dbSNP:769712221
603 603 g, t dbSNP:573835230
604 604 a, g dbSNP:150257776
605 605 a, t dbSNP:750489209
613 613 c, g dbSNP:758556104
618 618 a, g dbSNP:767503263
622 622 a, t dbSNP:752663568
623 623 c, t dbSNP:201073054
629 629 a, g dbSNP:756069021
638 638 c, g dbSNP:777591577
648 648 a, c, g, t dbSNP:749083432
656 656 a, g dbSNP:745328325
664 664 c, t dbSNP:557786197
668 668 c, t dbSNP:774930617
670 670 g, t dbSNP:747520012
673 673 c, g dbSNP:769094826
675 675 g, t dbSNP:777006347
676 676 g, t dbSNP:145508592
681 681 g, t dbSNP:770073014
684 684 a, g dbSNP:559436875
691 691 c, t dbSNP:200160626
693 693 c, t dbSNP:753709255
695 695 c, t dbSNP:373184843
699 699 c, g dbSNP:761810402
700 700 a, c dbSNP:764986364
704 704 c, t dbSNP:141267148
715 715 a, c dbSNP:757998904
720 720 c, t dbSNP:779606571
731 731 a, g dbSNP:751013061
732 732 a, g dbSNP:754458782
734 734 a, t dbSNP:146926014
737 737 c, t dbSNP:748660161
738 738 c, g dbSNP:770459446
744 744 c, t dbSNP:137877589
753 753 c, t dbSNP:749690063
762 762 a, g dbSNP:771141594
776 776 a, t dbSNP:774453035
782 782 a, g dbSNP:746162710
784 784 g, t dbSNP:772044493
796 796 -, c dbSNP:762294466
810 810 a, c dbSNP:775588057
823 823 c, g dbSNP:761716785
830 830 a, g dbSNP:765182780
836 836 a, c dbSNP:772953499
837 837 a, c dbSNP:762739987
838 838 -, c dbSNP:767936738
841 841 g, t dbSNP:546875772
843 843 c, t dbSNP:377447728
845 845 a, g dbSNP:751157788
848 848 c, t dbSNP:754725834
849 849 a, t dbSNP:370561561
850 850 c, g dbSNP:766902997
862 862 a, g dbSNP:773145526
864 864 a, g dbSNP:750820052
866 866 a, g dbSNP:559010746
878 878 -, c dbSNP:756753325
879 879 c, t dbSNP:533902103
883 883 c, g dbSNP:759084835
903 903 a, c dbSNP:569248499
904 904 a, g dbSNP:752211098
919 919 g, t dbSNP:755686967
921 921 -, ca dbSNP:766886344
923 923 -, cg dbSNP:752187047
923 923 c, g dbSNP:763757172
930 930 g, t dbSNP:537348427
933 933 c, g, t dbSNP:757826749
934 934 a, g, t dbSNP:557250916
941 941 c, t dbSNP:758509770
947 947 a, c dbSNP:780262061
948 948 g, t dbSNP:747031423
952 952 c, t dbSNP:768707595
972 972 c, g dbSNP:781314607
988 988 c, t dbSNP:749149020
992 992 c, g, t dbSNP:200586681
993 993 c, g, t dbSNP:759403823
996 996 c, g dbSNP:775270839
1005 1005 a, g dbSNP:780084584
1013 1013 a, g dbSNP:186351373
1032 1032 c, g dbSNP:755013240
1034 1034 c, t dbSNP:763669331
1037 1037 c, t dbSNP:753440628
1050 1050 a, c dbSNP:762177710
1054 1054 a, g dbSNP:765805593
1055 1055 a, g dbSNP:750688958
1056 1056 a, g dbSNP:552868043
1065 1065 -, a dbSNP:757885964
1068 1068 a, g dbSNP:201052217
1078 1078 a, g dbSNP:544743697
1079 1079 c, g dbSNP:368644338
1082 1082 a, t dbSNP:781227352
1090 1090 c, t dbSNP:748278231
1097 1097 a, c dbSNP:371623584
1126 1126 g, t dbSNP:373687274
1143 1143 a, g dbSNP:748051957
1175 1175 a, g dbSNP:771990238
1178 1178 a, c dbSNP:367791868
1186 1186 c, t dbSNP:190801974
1202 1202 c, t dbSNP:769857104
1205 1205 c, t dbSNP:752423341
1211 1211 a, c dbSNP:768445779
1217 1217 a, c dbSNP:530306798
1225 1225 a, g dbSNP:183044011
1228 1228 a, g dbSNP:761394201
1231 1231 g, t dbSNP:765607052
1241 1241 c, t dbSNP:566920318
1244 1244 a, g dbSNP:763515779
1259 1259 c, t dbSNP:766695241
1279 1279 c, t dbSNP:3760768
1282 1282 c, g dbSNP:751966512
1305 1305 a, t dbSNP:532663451
1368 1368 c, g dbSNP:552658327
1391 1391 c, g dbSNP:187571419
1392 1392 c, g dbSNP:113160292
1396 1396 c, t dbSNP:769777076
1446 1446 a, c dbSNP:569286407
1464 1464 a, g dbSNP:75765597
1469 1469 c, t dbSNP:554997634
1508 1508 g, t dbSNP:113690946
1510 1510 a, g dbSNP:567576698
1516 1516 a, g dbSNP:534011465
1556 1556 a, g dbSNP:11554339
1585 1585 c, g dbSNP:770771592
1619 1619 c, t dbSNP:374998691

Target ORF information:

RefSeq Version NM_001267870
Organism Homo sapiens (human)
Definition Homo sapiens hydroxysteroid (11-beta) dehydrogenase 1-like (HSD11B1L), transcript variant h, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001267870

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
ATGAAGGTGC TTCTCCTCAC AGGGCTGGGG GCCCTGTTCT TCGCCTATTA TTGGGATGAC 
AACTTCGACC CAGGTAAACT TTGTGAGCTA CGTGCAACTG ACGTCGCGGG CGCTGCCCAG
CCTGACGGAC AGCAAGGGCT CCCTGGTGGT GGTGTCCTCG CTGCTCGGCC GCGTGCCCAC
GTCGTTCTCC ACTCCCTACT CGGCGGCCAA GTTTGCGCTG GACGGCTTCT TCGGCTCCCT
GCGGCGGGAG CTGGACGTGC AGGACGTGAA CGTGGCCATC ACCATGTGCG TCCTGGGCCT
CCGAGATCGC GCCTCCGCCG CCGAGGCAGT CAGGGGAGTC ACGAGGGTCA AGGCGGCCCC
GGGGCCCAAG GCAGCCCTGG CCGTGATCCG CGGCGGCGCC ACGCGCGCGG CCGGCGTCTT
CTACCCGTGG CGTTTCCGCC TGCTGTGCTT GCTCCGGCGC TGGCTACCGC GCCCGCGGGC
CTGGTTTATC CGCCAGGAGC TCAACGTCAC GGCCGCGGCA GCCTGAGCAC CGGGGGGTGC
CCCTCCAGTC CCAGACGGCA ATGTTCCTCC CTCCAACTGT CCCTGGAGCC AGAACACTCA
CAGAGACACC CCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu02666
Accession Version NM_198706.2
Sequence Information ORF Nucleotide Sequence (Length: 861bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-APR-2015
Organism Homo sapiens (human)
Product hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform b precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA343367.1, AY268352.1 and AI871311.1. On Jun 26, 2012 this sequence version replaced gi:38424084. Summary: This gene is a member of the hydroxysteroid dehydrogenase family. The encoded protein is similar to an enzyme that catalyzes the interconversion of inactive to active glucocorticoids (e.g. cortisone). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jun 2012]. Transcript Variant: This variant (b) lacks an exon and a portion of the 5' coding region, and initiates translation at a downstream in-frame start codon, compared to variant g. The encoded isoform (b) is shorter than isoform g. ##Evidence-Data-START## Transcript exon combination :: AY268352.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
ATGAAGGTGC TTCTCCTCAC AGGGCTGGGG GCCCTGTTCT TCGCCTATTA TTGGGATGAC 
AACTTCGACC CAGCCAGCCT CCAGGGAGCG CGAGTGCTGC TGACAGGGGC CAACGCTGGT
GTTGGTGAGG AGCTGGCCTA TCACTACGCG CGTCTGGGCT CCCACCTGGT GCTCACTGCC
CACACTGAGG CTCTCCTGCA GAAGGTGGTA GGGAACTGCC GGAAGCTGGG CGCCCCCAAG
GTCTTCTACA TCGCGGCGGA CATGGCCTCC CCTGAGGCGC CCGAGAGCGT GGTGCAGTTT
GCGCTGGACA AGCTGGGCGG GCTGGACTAC CTCGTGCTGA ACCACATCGG CGGCGCCCCG
GCCGGCACGC GAGCCCGCAG CCCCCAGGCA ACTCGCTGGC TCATGCAGGT AAACTTTGTG
AGCTACGTGC AACTGACGTC GCGGGCGCTG CCCAGCCTGA CGGACAGCAA GGGCTCCCTG
GTGGTGGTGT CCTCGCTGCT CGGCCGCGTG CCCACGTCGT TCTCCACTCC CTACTCGGCG
GCCAAGTTTG CGCTGGACGG CTTCTTCGGC TCCCTGCGGC GGGAGCTGGA CGTGCAGGAC
GTGAACGTGG CCATCACCAT GTGCGTCCTG GGCCTCCGAG ATCGCGCCTC CGCCGCCGAG
GCAGTCAGGG GAGTCACGAG GGTCAAGGCG GCCCCGGGGC CCAAGGCAGC CCTGGCCGTG
ATCCGCGGCG GCGCCACGCG CGCGGCCGGC GTCTTCTACC CGTGGCGTTT CCGCCTGCTG
TGCTTGCTCC GGCGCTGGCT ACCGCGCCCG CGGGCCTGGT TTATCCGCCA GGAGCTCAAC
GTCACGGCCG CGGCAGCCTG A
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_941995.1
CDS522..1382
Misc Feature(1)501..503(+)
Misc Feature(2)600..1286(+)
Misc Feature(3)615..1109(+)
Misc Feature(4)627..1160(+)
Misc Feature(5)933..1067(+)
Exon (1)1..507
Gene:HSD11B1L
Gene Synonym:
Exon (2)508..594
Gene:HSD11B1L
Gene Synonym:
Exon (3)595..725
Gene:HSD11B1L
Gene Synonym:
Exon (4)726..837
Gene:HSD11B1L
Gene Synonym:
Exon (5)838..929
Gene:HSD11B1L
Gene Synonym:
Exon (6)930..1023
Gene:HSD11B1L
Gene Synonym:
Exon (7)1024..1189
Gene:HSD11B1L
Gene Synonym:
Exon (8)1190..1960
Gene:HSD11B1L
Gene Synonym:
Translation
Position Chain Variation Link
9 9 a, g dbSNP:536571939
29 29 c, g dbSNP:374470108
36 36 c, g dbSNP:553183853
120 120 a, g dbSNP:368349880
214 214 a, g dbSNP:777133816
221 221 c, t dbSNP:572960614
222 222 c, g dbSNP:545227692
233 233 c, t dbSNP:564912252
278 278 c, g, t dbSNP:372389691
296 296 c, t dbSNP:547566141
301 301 a, g dbSNP:759306534
304 304 a, g dbSNP:375379743
330 330 c, g dbSNP:560575101
340 340 -, c dbSNP:34175618
353 353 a, g dbSNP:529595991
371 371 c, t dbSNP:369435874
394 394 a, g dbSNP:113651086
397 397 c, g dbSNP:371409148
461 461 a, g dbSNP:748861579
462 462 a, g dbSNP:540534380
475 475 c, g dbSNP:560881938
507 507 a, g dbSNP:770430936
514 514 a, c dbSNP:377450352
520 520 a, c dbSNP:754635706
521 521 c, t dbSNP:371137127
547 547 a, t dbSNP:752208098
551 551 a, g, t dbSNP:755580266
555 555 c, g dbSNP:749812625
563 563 c, t dbSNP:771610051
564 564 a, g dbSNP:761542737
571 571 a, g dbSNP:746243674
575 575 a, g dbSNP:772298551
581 581 a, c dbSNP:549857184
583 583 a, g dbSNP:760751212
587 587 c, t dbSNP:375620357
593 593 a, t dbSNP:151120147
595 595 c, t dbSNP:768905891
605 605 a, g dbSNP:776668734
611 611 a, g dbSNP:748248147
612 612 c, g, t dbSNP:770811587
613 613 a, c, g dbSNP:759313781
626 626 -, ag dbSNP:768172247
631 631 c, t dbSNP:775398718
632 632 c, t dbSNP:760385158
634 634 a, g dbSNP:763863867
635 635 c, t dbSNP:753361319
636 636 a, g dbSNP:756833114
643 643 c, t dbSNP:765782828
645 645 -, gtga dbSNP:750912624
646 646 a, g dbSNP:148042659
664 664 a, c, g dbSNP:200835892
670 670 c, t dbSNP:780249226
671 671 a, g dbSNP:141021013
672 672 c, t dbSNP:535314623
673 673 c, g dbSNP:781422805
681 681 c, t dbSNP:748156322
689 689 a, g dbSNP:374641413
690 690 a, g dbSNP:765889177
731 731 a, g dbSNP:781519298
733 733 a, g dbSNP:780048368
734 734 c, g dbSNP:746744557
755 755 c, t dbSNP:768557969
764 764 a, c dbSNP:199995247
769 769 a, g dbSNP:776637614
776 776 c, g dbSNP:761527897
785 785 a, g dbSNP:528046422
791 791 c, g dbSNP:769533807
804 804 a, g dbSNP:551077796
826 826 c, t dbSNP:762554836
840 840 a, g dbSNP:759058739
848 848 -, t dbSNP:746809651
869 869 a, c dbSNP:746940980
871 871 a, g dbSNP:768756023
872 872 a, c dbSNP:781111075
875 875 c, t dbSNP:747977283
884 884 c, t dbSNP:769291082
886 886 a, g dbSNP:772922135
892 892 a, g dbSNP:762308388
894 894 a, g dbSNP:770458522
899 899 a, c dbSNP:773914890
902 902 a, c dbSNP:760001903
911 911 a, g dbSNP:553392555
917 917 c, t dbSNP:768036784
936 936 -, tt dbSNP:769712221
938 938 g, t dbSNP:573835230
939 939 a, g dbSNP:150257776
940 940 a, t dbSNP:750489209
948 948 c, g dbSNP:758556104
953 953 a, g dbSNP:767503263
957 957 a, t dbSNP:752663568
958 958 c, t dbSNP:201073054
964 964 a, g dbSNP:756069021
973 973 c, g dbSNP:777591577
983 983 a, c, g, t dbSNP:749083432
991 991 a, g dbSNP:745328325
999 999 c, t dbSNP:557786197
1003 1003 c, t dbSNP:774930617
1005 1005 g, t dbSNP:747520012
1008 1008 c, g dbSNP:769094826
1010 1010 g, t dbSNP:777006347
1011 1011 g, t dbSNP:145508592
1016 1016 g, t dbSNP:770073014
1019 1019 a, g dbSNP:559436875
1026 1026 c, t dbSNP:200160626
1028 1028 c, t dbSNP:753709255
1030 1030 c, t dbSNP:373184843
1034 1034 c, g dbSNP:761810402
1035 1035 a, c dbSNP:764986364
1039 1039 c, t dbSNP:141267148
1050 1050 a, c dbSNP:757998904
1055 1055 c, t dbSNP:779606571
1066 1066 a, g dbSNP:751013061
1067 1067 a, g dbSNP:754458782
1069 1069 a, t dbSNP:146926014
1072 1072 c, t dbSNP:748660161
1073 1073 c, g dbSNP:770459446
1079 1079 c, t dbSNP:137877589
1088 1088 c, t dbSNP:749690063
1097 1097 a, g dbSNP:771141594
1111 1111 a, t dbSNP:774453035
1117 1117 a, g dbSNP:746162710
1119 1119 g, t dbSNP:772044493
1131 1131 -, c dbSNP:762294466
1145 1145 a, c dbSNP:775588057
1158 1158 c, g dbSNP:761716785
1165 1165 a, g dbSNP:765182780
1171 1171 a, c dbSNP:772953499
1172 1172 a, c dbSNP:762739987
1173 1173 -, c dbSNP:767936738
1176 1176 g, t dbSNP:546875772
1178 1178 c, t dbSNP:377447728
1180 1180 a, g dbSNP:751157788
1183 1183 c, t dbSNP:754725834
1184 1184 a, t dbSNP:370561561
1185 1185 c, g dbSNP:766902997
1197 1197 a, g dbSNP:773145526
1199 1199 a, g dbSNP:750820052
1201 1201 a, g dbSNP:559010746
1213 1213 -, c dbSNP:756753325
1214 1214 c, t dbSNP:533902103
1218 1218 c, g dbSNP:759084835
1238 1238 a, c dbSNP:569248499
1239 1239 a, g dbSNP:752211098
1254 1254 g, t dbSNP:755686967
1256 1256 -, ca dbSNP:766886344
1258 1258 -, cg dbSNP:752187047
1258 1258 c, g dbSNP:763757172
1265 1265 g, t dbSNP:537348427
1268 1268 c, g, t dbSNP:757826749
1269 1269 a, g, t dbSNP:557250916
1276 1276 c, t dbSNP:758509770
1282 1282 a, c dbSNP:780262061
1283 1283 g, t dbSNP:747031423
1287 1287 c, t dbSNP:768707595
1307 1307 c, g dbSNP:781314607
1323 1323 c, t dbSNP:749149020
1327 1327 c, g, t dbSNP:200586681
1328 1328 c, g, t dbSNP:759403823
1331 1331 c, g dbSNP:775270839
1340 1340 a, g dbSNP:780084584
1348 1348 a, g dbSNP:186351373
1367 1367 c, g dbSNP:755013240
1369 1369 c, t dbSNP:763669331
1372 1372 c, t dbSNP:753440628
1385 1385 a, c dbSNP:762177710
1389 1389 a, g dbSNP:765805593
1390 1390 a, g dbSNP:750688958
1391 1391 a, g dbSNP:552868043
1400 1400 -, a dbSNP:757885964
1403 1403 a, g dbSNP:201052217
1413 1413 a, g dbSNP:544743697
1414 1414 c, g dbSNP:368644338
1417 1417 a, t dbSNP:781227352
1425 1425 c, t dbSNP:748278231
1432 1432 a, c dbSNP:371623584
1461 1461 g, t dbSNP:373687274
1478 1478 a, g dbSNP:748051957
1510 1510 a, g dbSNP:771990238
1513 1513 a, c dbSNP:367791868
1521 1521 c, t dbSNP:190801974
1537 1537 c, t dbSNP:769857104
1540 1540 c, t dbSNP:752423341
1546 1546 a, c dbSNP:768445779
1552 1552 a, c dbSNP:530306798
1560 1560 a, g dbSNP:183044011
1563 1563 a, g dbSNP:761394201
1566 1566 g, t dbSNP:765607052
1576 1576 c, t dbSNP:566920318
1579 1579 a, g dbSNP:763515779
1594 1594 c, t dbSNP:766695241
1614 1614 c, t dbSNP:3760768
1617 1617 c, g dbSNP:751966512
1640 1640 a, t dbSNP:532663451
1703 1703 c, g dbSNP:552658327
1726 1726 c, g dbSNP:187571419
1727 1727 c, g dbSNP:113160292
1731 1731 c, t dbSNP:769777076
1781 1781 a, c dbSNP:569286407
1799 1799 a, g dbSNP:75765597
1804 1804 c, t dbSNP:554997634
1843 1843 g, t dbSNP:113690946
1845 1845 a, g dbSNP:567576698
1851 1851 a, g dbSNP:534011465
1891 1891 a, g dbSNP:11554339
1920 1920 c, g dbSNP:770771592
1954 1954 c, t dbSNP:374998691

Target ORF information:

RefSeq Version NM_198706
Organism Homo sapiens (human)
Definition Homo sapiens hydroxysteroid (11-beta) dehydrogenase 1-like (HSD11B1L), transcript variant b, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_198706

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
ATGAAGGTGC TTCTCCTCAC AGGGCTGGGG GCCCTGTTCT TCGCCTATTA TTGGGATGAC 
AACTTCGACC CAGCCAGCCT CCAGGGAGCG CGAGTGCTGC TGACAGGGGC CAACGCTGGT
GTTGGTGAGG AGCTGGCCTA TCACTACGCG CGTCTGGGCT CCCACCTGGT GCTCACTGCC
CACACTGAGG CTCTCCTGCA GAAGGTGGTA GGGAACTGCC GGAAGCTGGG CGCCCCCAAG
GTCTTCTACA TCGCGGCGGA CATGGCCTCC CCTGAGGCGC CCGAGAGCGT GGTGCAGTTT
GCGCTGGACA AGCTGGGCGG GCTGGACTAC CTCGTGCTGA ACCACATCGG CGGCGCCCCG
GCCGGCACGC GAGCCCGCAG CCCCCAGGCA ACTCGCTGGC TCATGCAGGT AAACTTTGTG
AGCTACGTGC AACTGACGTC GCGGGCGCTG CCCAGCCTGA CGGACAGCAA GGGCTCCCTG
GTGGTGGTGT CCTCGCTGCT CGGCCGCGTG CCCACGTCGT TCTCCACTCC CTACTCGGCG
GCCAAGTTTG CGCTGGACGG CTTCTTCGGC TCCCTGCGGC GGGAGCTGGA CGTGCAGGAC
GTGAACGTGG CCATCACCAT GTGCGTCCTG GGCCTCCGAG ATCGCGCCTC CGCCGCCGAG
GCAGTCAGGG GAGTCACGAG GGTCAAGGCG GCCCCGGGGC CCAAGGCAGC CCTGGCCGTG
ATCCGCGGCG GCGCCACGCG CGCGGCCGGC GTCTTCTACC CGTGGCGTTT CCGCCTGCTG
TGCTTGCTCC GGCGCTGGCT ACCGCGCCCG CGGGCCTGGT TTATCCGCCA GGAGCTCAAC
GTCACGGCCG CGGCAGCCTG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu02668
Accession Version NM_198708.2
Sequence Information ORF Nucleotide Sequence (Length: 459bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-APR-2015
Organism Homo sapiens (human)
Product hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform d
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA343367.1, AY268354.1 and AI871311.1. On Jun 26, 2012 this sequence version replaced gi:38424082. Summary: This gene is a member of the hydroxysteroid dehydrogenase family. The encoded protein is similar to an enzyme that catalyzes the interconversion of inactive to active glucocorticoids (e.g. cortisone). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jun 2012]. Transcript Variant: This variant (d) has multiple differences in the coding region, and initiates translation at an alternate downstream in-frame start codon, compared to variant g. The encoded isoform (d) is shorter than isoform g. Variants d and j encode the same protein. ##Evidence-Data-START## Transcript exon combination :: AY268354.1, BC053546.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2142348 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
ATGCAGGTAA ACTTTGTGAG CTACGTGCAA CTGACGTCGC GGGCGCTGCC CAGCCTGACG 
GACAGCAAGG GCTCCCTGGT GGTGGTGTCC TCGCTGCTCG GCCGCGTGCC CACGTCGTTC
TCCACTCCCT ACTCGGCGGC CAAGTTTGCG CTGGACGGCT TCTTCGGCTC CCTGCGGCGG
GAGCTGGACG TGCAGGACGT GAACGTGGCC ATCACCATGT GCGTCCTGGG CCTCCGAGAT
CGCGCCTCCG CCGCCGAGGC AGTCAGGGGA GTCACGAGGG TCAAGGCGGC CCCGGGGCCC
AAGGCAGCCC TGGCCGTGAT CCGCGGCGGC GCCACGCGCG CGGCCGGCGT CTTCTACCCG
TGGCGTTTCC GCCTGCTGTG CTTGCTCCGG CGCTGGCTAC CGCGCCCGCG GGCCTGGTTT
ATCCGCCAGG AGCTCAACGT CACGGCCGCG GCAGCCTGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_941997.1
CDS812..1270
Misc Feature(1)707..709(+)
Misc Feature(2)812..1174(+)
Misc Feature(3)821..955(+)
Exon (1)1..507
Gene:HSD11B1L
Gene Synonym:
Exon (2)508..594
Gene:HSD11B1L
Gene Synonym:
Exon (3)595..725
Gene:HSD11B1L
Gene Synonym:
Exon (4)726..817
Gene:HSD11B1L
Gene Synonym:
Exon (5)818..911
Gene:HSD11B1L
Gene Synonym:
Exon (6)912..1077
Gene:HSD11B1L
Gene Synonym:
Exon (7)1078..1848
Gene:HSD11B1L
Gene Synonym:
Translation
Position Chain Variation Link
9 9 a, g dbSNP:536571939
29 29 c, g dbSNP:374470108
36 36 c, g dbSNP:553183853
120 120 a, g dbSNP:368349880
214 214 a, g dbSNP:777133816
221 221 c, t dbSNP:572960614
222 222 c, g dbSNP:545227692
233 233 c, t dbSNP:564912252
278 278 c, g, t dbSNP:372389691
296 296 c, t dbSNP:547566141
301 301 a, g dbSNP:759306534
304 304 a, g dbSNP:375379743
330 330 c, g dbSNP:560575101
340 340 -, c dbSNP:34175618
353 353 a, g dbSNP:529595991
371 371 c, t dbSNP:369435874
394 394 a, g dbSNP:113651086
397 397 c, g dbSNP:371409148
461 461 a, g dbSNP:748861579
462 462 a, g dbSNP:540534380
475 475 c, g dbSNP:560881938
507 507 a, g dbSNP:770430936
514 514 a, c dbSNP:377450352
520 520 a, c dbSNP:754635706
521 521 c, t dbSNP:371137127
547 547 a, t dbSNP:752208098
551 551 a, g, t dbSNP:755580266
555 555 c, g dbSNP:749812625
563 563 c, t dbSNP:771610051
564 564 a, g dbSNP:761542737
571 571 a, g dbSNP:746243674
575 575 a, g dbSNP:772298551
581 581 a, c dbSNP:549857184
583 583 a, g dbSNP:760751212
587 587 c, t dbSNP:375620357
593 593 a, t dbSNP:151120147
595 595 c, t dbSNP:768905891
605 605 a, g dbSNP:776668734
611 611 a, g dbSNP:748248147
612 612 c, g, t dbSNP:770811587
613 613 a, c, g dbSNP:759313781
626 626 -, ag dbSNP:768172247
631 631 c, t dbSNP:775398718
632 632 c, t dbSNP:760385158
634 634 a, g dbSNP:763863867
635 635 c, t dbSNP:753361319
636 636 a, g dbSNP:756833114
643 643 c, t dbSNP:765782828
645 645 -, gtga dbSNP:750912624
646 646 a, g dbSNP:148042659
664 664 a, c, g dbSNP:200835892
670 670 c, t dbSNP:780249226
671 671 a, g dbSNP:141021013
672 672 c, t dbSNP:535314623
673 673 c, g dbSNP:781422805
681 681 c, t dbSNP:748156322
689 689 a, g dbSNP:374641413
690 690 a, g dbSNP:765889177
728 728 a, g dbSNP:759058739
736 736 -, t dbSNP:746809651
757 757 a, c dbSNP:746940980
759 759 a, g dbSNP:768756023
760 760 a, c dbSNP:781111075
763 763 c, t dbSNP:747977283
772 772 c, t dbSNP:769291082
774 774 a, g dbSNP:772922135
780 780 a, g dbSNP:762308388
782 782 a, g dbSNP:770458522
787 787 a, c dbSNP:773914890
790 790 a, c dbSNP:760001903
799 799 a, g dbSNP:553392555
805 805 c, t dbSNP:768036784
824 824 -, tt dbSNP:769712221
826 826 g, t dbSNP:573835230
827 827 a, g dbSNP:150257776
828 828 a, t dbSNP:750489209
836 836 c, g dbSNP:758556104
841 841 a, g dbSNP:767503263
845 845 a, t dbSNP:752663568
846 846 c, t dbSNP:201073054
852 852 a, g dbSNP:756069021
861 861 c, g dbSNP:777591577
871 871 a, c, g, t dbSNP:749083432
879 879 a, g dbSNP:745328325
887 887 c, t dbSNP:557786197
891 891 c, t dbSNP:774930617
893 893 g, t dbSNP:747520012
896 896 c, g dbSNP:769094826
898 898 g, t dbSNP:777006347
899 899 g, t dbSNP:145508592
904 904 g, t dbSNP:770073014
907 907 a, g dbSNP:559436875
914 914 c, t dbSNP:200160626
916 916 c, t dbSNP:753709255
918 918 c, t dbSNP:373184843
922 922 c, g dbSNP:761810402
923 923 a, c dbSNP:764986364
927 927 c, t dbSNP:141267148
938 938 a, c dbSNP:757998904
943 943 c, t dbSNP:779606571
954 954 a, g dbSNP:751013061
955 955 a, g dbSNP:754458782
957 957 a, t dbSNP:146926014
960 960 c, t dbSNP:748660161
961 961 c, g dbSNP:770459446
967 967 c, t dbSNP:137877589
976 976 c, t dbSNP:749690063
985 985 a, g dbSNP:771141594
999 999 a, t dbSNP:774453035
1005 1005 a, g dbSNP:746162710
1007 1007 g, t dbSNP:772044493
1019 1019 -, c dbSNP:762294466
1033 1033 a, c dbSNP:775588057
1046 1046 c, g dbSNP:761716785
1053 1053 a, g dbSNP:765182780
1059 1059 a, c dbSNP:772953499
1060 1060 a, c dbSNP:762739987
1061 1061 -, c dbSNP:767936738
1064 1064 g, t dbSNP:546875772
1066 1066 c, t dbSNP:377447728
1068 1068 a, g dbSNP:751157788
1071 1071 c, t dbSNP:754725834
1072 1072 a, t dbSNP:370561561
1073 1073 c, g dbSNP:766902997
1085 1085 a, g dbSNP:773145526
1087 1087 a, g dbSNP:750820052
1089 1089 a, g dbSNP:559010746
1101 1101 -, c dbSNP:756753325
1102 1102 c, t dbSNP:533902103
1106 1106 c, g dbSNP:759084835
1126 1126 a, c dbSNP:569248499
1127 1127 a, g dbSNP:752211098
1142 1142 g, t dbSNP:755686967
1144 1144 -, ca dbSNP:766886344
1146 1146 -, cg dbSNP:752187047
1146 1146 c, g dbSNP:763757172
1153 1153 g, t dbSNP:537348427
1156 1156 c, g, t dbSNP:757826749
1157 1157 a, g, t dbSNP:557250916
1164 1164 c, t dbSNP:758509770
1170 1170 a, c dbSNP:780262061
1171 1171 g, t dbSNP:747031423
1175 1175 c, t dbSNP:768707595
1195 1195 c, g dbSNP:781314607
1211 1211 c, t dbSNP:749149020
1215 1215 c, g, t dbSNP:200586681
1216 1216 c, g, t dbSNP:759403823
1219 1219 c, g dbSNP:775270839
1228 1228 a, g dbSNP:780084584
1236 1236 a, g dbSNP:186351373
1255 1255 c, g dbSNP:755013240
1257 1257 c, t dbSNP:763669331
1260 1260 c, t dbSNP:753440628
1273 1273 a, c dbSNP:762177710
1277 1277 a, g dbSNP:765805593
1278 1278 a, g dbSNP:750688958
1279 1279 a, g dbSNP:552868043
1288 1288 -, a dbSNP:757885964
1291 1291 a, g dbSNP:201052217
1301 1301 a, g dbSNP:544743697
1302 1302 c, g dbSNP:368644338
1305 1305 a, t dbSNP:781227352
1313 1313 c, t dbSNP:748278231
1320 1320 a, c dbSNP:371623584
1349 1349 g, t dbSNP:373687274
1366 1366 a, g dbSNP:748051957
1398 1398 a, g dbSNP:771990238
1401 1401 a, c dbSNP:367791868
1409 1409 c, t dbSNP:190801974
1425 1425 c, t dbSNP:769857104
1428 1428 c, t dbSNP:752423341
1434 1434 a, c dbSNP:768445779
1440 1440 a, c dbSNP:530306798
1448 1448 a, g dbSNP:183044011
1451 1451 a, g dbSNP:761394201
1454 1454 g, t dbSNP:765607052
1464 1464 c, t dbSNP:566920318
1467 1467 a, g dbSNP:763515779
1482 1482 c, t dbSNP:766695241
1502 1502 c, t dbSNP:3760768
1505 1505 c, g dbSNP:751966512
1528 1528 a, t dbSNP:532663451
1591 1591 c, g dbSNP:552658327
1614 1614 c, g dbSNP:187571419
1615 1615 c, g dbSNP:113160292
1619 1619 c, t dbSNP:769777076
1669 1669 a, c dbSNP:569286407
1687 1687 a, g dbSNP:75765597
1692 1692 c, t dbSNP:554997634
1731 1731 g, t dbSNP:113690946
1733 1733 a, g dbSNP:567576698
1739 1739 a, g dbSNP:534011465
1779 1779 a, g dbSNP:11554339
1808 1808 c, g dbSNP:770771592
1842 1842 c, t dbSNP:374998691

Target ORF information:

RefSeq Version NM_198708
Organism Homo sapiens (human)
Definition Homo sapiens hydroxysteroid (11-beta) dehydrogenase 1-like (HSD11B1L), transcript variant d, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_198708

ORF Insert Sequence:

1
61
121
181
241
301
361
421
ATGCAGGTAA ACTTTGTGAG CTACGTGCAA CTGACGTCGC GGGCGCTGCC CAGCCTGACG 
GACAGCAAGG GCTCCCTGGT GGTGGTGTCC TCGCTGCTCG GCCGCGTGCC CACGTCGTTC
TCCACTCCCT ACTCGGCGGC CAAGTTTGCG CTGGACGGCT TCTTCGGCTC CCTGCGGCGG
GAGCTGGACG TGCAGGACGT GAACGTGGCC ATCACCATGT GCGTCCTGGG CCTCCGAGAT
CGCGCCTCCG CCGCCGAGGC AGTCAGGGGA GTCACGAGGG TCAAGGCGGC CCCGGGGCCC
AAGGCAGCCC TGGCCGTGAT CCGCGGCGGC GCCACGCGCG CGGCCGGCGT CTTCTACCCG
TGGCGTTTCC GCCTGCTGTG CTTGCTCCGG CGCTGGCTAC CGCGCCCGCG GGCCTGGTTT
ATCCGCCAGG AGCTCAACGT CACGGCCGCG GCAGCCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu02668
Accession Version NM_001267869.1
Sequence Information ORF Nucleotide Sequence (Length: 459bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-APR-2015
Organism Homo sapiens (human)
Product hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform d
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA343367.1, BC094798.1, AC011499.5 and AI871311.1. Summary: This gene is a member of the hydroxysteroid dehydrogenase family. The encoded protein is similar to an enzyme that catalyzes the interconversion of inactive to active glucocorticoids (e.g. cortisone). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jun 2012]. Transcript Variant: This variant (j) has multiple differences in the coding region, and initiates translation at an alternate downstream in-frame start codon, compared to variant g. The encoded isoform (d) is shorter than isoform g. Variants d and j encode the same protein. ##Evidence-Data-START## Transcript exon combination :: BC094798.1, BG716680.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2142680 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
ATGCAGGTAA ACTTTGTGAG CTACGTGCAA CTGACGTCGC GGGCGCTGCC CAGCCTGACG 
GACAGCAAGG GCTCCCTGGT GGTGGTGTCC TCGCTGCTCG GCCGCGTGCC CACGTCGTTC
TCCACTCCCT ACTCGGCGGC CAAGTTTGCG CTGGACGGCT TCTTCGGCTC CCTGCGGCGG
GAGCTGGACG TGCAGGACGT GAACGTGGCC ATCACCATGT GCGTCCTGGG CCTCCGAGAT
CGCGCCTCCG CCGCCGAGGC AGTCAGGGGA GTCACGAGGG TCAAGGCGGC CCCGGGGCCC
AAGGCAGCCC TGGCCGTGAT CCGCGGCGGC GCCACGCGCG CGGCCGGCGT CTTCTACCCG
TGGCGTTTCC GCCTGCTGTG CTTGCTCCGG CGCTGGCTAC CGCGCCCGCG GGCCTGGTTT
ATCCGCCAGG AGCTCAACGT CACGGCCGCG GCAGCCTGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_001254798.1
CDS749..1207
Misc Feature(1)644..646(+)
Misc Feature(2)749..1111(+)
Misc Feature(3)758..892(+)
Exon (1)1..507
Gene:HSD11B1L
Gene Synonym:
Exon (2)508..662
Gene:HSD11B1L
Gene Synonym:
Exon (3)663..754
Gene:HSD11B1L
Gene Synonym:
Exon (4)755..848
Gene:HSD11B1L
Gene Synonym:
Exon (5)849..1014
Gene:HSD11B1L
Gene Synonym:
Exon (6)1015..1785
Gene:HSD11B1L
Gene Synonym:
Translation
Position Chain Variation Link
9 9 a, g dbSNP:536571939
29 29 c, g dbSNP:374470108
36 36 c, g dbSNP:553183853
120 120 a, g dbSNP:368349880
214 214 a, g dbSNP:777133816
221 221 c, t dbSNP:572960614
222 222 c, g dbSNP:545227692
233 233 c, t dbSNP:564912252
278 278 c, g, t dbSNP:372389691
296 296 c, t dbSNP:547566141
301 301 a, g dbSNP:759306534
304 304 a, g dbSNP:375379743
330 330 c, g dbSNP:560575101
340 340 -, c dbSNP:34175618
353 353 a, g dbSNP:529595991
371 371 c, t dbSNP:369435874
394 394 a, g dbSNP:113651086
397 397 c, g dbSNP:371409148
461 461 a, g dbSNP:748861579
462 462 a, g dbSNP:540534380
475 475 c, g dbSNP:560881938
507 507 a, g dbSNP:770430936
516 516 a, c, t dbSNP:779595609
517 517 c, t dbSNP:372234338
519 519 -, c dbSNP:35181288
519 519 c, t dbSNP:762549635
520 520 a, g dbSNP:371417226
532 532 c, t dbSNP:768905891
542 542 a, g dbSNP:776668734
548 548 a, g dbSNP:748248147
549 549 c, g, t dbSNP:770811587
550 550 a, c, g dbSNP:759313781
563 563 -, ag dbSNP:768172247
568 568 c, t dbSNP:775398718
569 569 c, t dbSNP:760385158
571 571 a, g dbSNP:763863867
572 572 c, t dbSNP:753361319
573 573 a, g dbSNP:756833114
580 580 c, t dbSNP:765782828
582 582 -, gtga dbSNP:750912624
583 583 a, g dbSNP:148042659
601 601 a, c, g dbSNP:200835892
607 607 c, t dbSNP:780249226
608 608 a, g dbSNP:141021013
609 609 c, t dbSNP:535314623
610 610 c, g dbSNP:781422805
618 618 c, t dbSNP:748156322
626 626 a, g dbSNP:374641413
627 627 a, g dbSNP:765889177
665 665 a, g dbSNP:759058739
673 673 -, t dbSNP:746809651
694 694 a, c dbSNP:746940980
696 696 a, g dbSNP:768756023
697 697 a, c dbSNP:781111075
700 700 c, t dbSNP:747977283
709 709 c, t dbSNP:769291082
711 711 a, g dbSNP:772922135
717 717 a, g dbSNP:762308388
719 719 a, g dbSNP:770458522
724 724 a, c dbSNP:773914890
727 727 a, c dbSNP:760001903
736 736 a, g dbSNP:553392555
742 742 c, t dbSNP:768036784
761 761 -, tt dbSNP:769712221
763 763 g, t dbSNP:573835230
764 764 a, g dbSNP:150257776
765 765 a, t dbSNP:750489209
773 773 c, g dbSNP:758556104
778 778 a, g dbSNP:767503263
782 782 a, t dbSNP:752663568
783 783 c, t dbSNP:201073054
789 789 a, g dbSNP:756069021
798 798 c, g dbSNP:777591577
808 808 a, c, g, t dbSNP:749083432
816 816 a, g dbSNP:745328325
824 824 c, t dbSNP:557786197
828 828 c, t dbSNP:774930617
830 830 g, t dbSNP:747520012
833 833 c, g dbSNP:769094826
835 835 g, t dbSNP:777006347
836 836 g, t dbSNP:145508592
841 841 g, t dbSNP:770073014
844 844 a, g dbSNP:559436875
851 851 c, t dbSNP:200160626
853 853 c, t dbSNP:753709255
855 855 c, t dbSNP:373184843
859 859 c, g dbSNP:761810402
860 860 a, c dbSNP:764986364
864 864 c, t dbSNP:141267148
875 875 a, c dbSNP:757998904
880 880 c, t dbSNP:779606571
891 891 a, g dbSNP:751013061
892 892 a, g dbSNP:754458782
894 894 a, t dbSNP:146926014
897 897 c, t dbSNP:748660161
898 898 c, g dbSNP:770459446
904 904 c, t dbSNP:137877589
913 913 c, t dbSNP:749690063
922 922 a, g dbSNP:771141594
936 936 a, t dbSNP:774453035
942 942 a, g dbSNP:746162710
944 944 g, t dbSNP:772044493
956 956 -, c dbSNP:762294466
970 970 a, c dbSNP:775588057
983 983 c, g dbSNP:761716785
990 990 a, g dbSNP:765182780
996 996 a, c dbSNP:772953499
997 997 a, c dbSNP:762739987
998 998 -, c dbSNP:767936738
1001 1001 g, t dbSNP:546875772
1003 1003 c, t dbSNP:377447728
1005 1005 a, g dbSNP:751157788
1008 1008 c, t dbSNP:754725834
1009 1009 a, t dbSNP:370561561
1010 1010 c, g dbSNP:766902997
1022 1022 a, g dbSNP:773145526
1024 1024 a, g dbSNP:750820052
1026 1026 a, g dbSNP:559010746
1038 1038 -, c dbSNP:756753325
1039 1039 c, t dbSNP:533902103
1043 1043 c, g dbSNP:759084835
1063 1063 a, c dbSNP:569248499
1064 1064 a, g dbSNP:752211098
1079 1079 g, t dbSNP:755686967
1081 1081 -, ca dbSNP:766886344
1083 1083 -, cg dbSNP:752187047
1083 1083 c, g dbSNP:763757172
1090 1090 g, t dbSNP:537348427
1093 1093 c, g, t dbSNP:757826749
1094 1094 a, g, t dbSNP:557250916
1101 1101 c, t dbSNP:758509770
1107 1107 a, c dbSNP:780262061
1108 1108 g, t dbSNP:747031423
1112 1112 c, t dbSNP:768707595
1132 1132 c, g dbSNP:781314607
1148 1148 c, t dbSNP:749149020
1152 1152 c, g, t dbSNP:200586681
1153 1153 c, g, t dbSNP:759403823
1156 1156 c, g dbSNP:775270839
1165 1165 a, g dbSNP:780084584
1173 1173 a, g dbSNP:186351373
1192 1192 c, g dbSNP:755013240
1194 1194 c, t dbSNP:763669331
1197 1197 c, t dbSNP:753440628
1210 1210 a, c dbSNP:762177710
1214 1214 a, g dbSNP:765805593
1215 1215 a, g dbSNP:750688958
1216 1216 a, g dbSNP:552868043
1225 1225 -, a dbSNP:757885964
1228 1228 a, g dbSNP:201052217
1238