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KCNF1 potassium channel, voltage gated modifier subfamily F, member 1 [Homo sapiens (human)]

Gene Symbol KCNF1
Entrez Gene ID 3754
Full Name potassium channel, voltage gated modifier subfamily F, member 1
Synonyms IK8, KCNF, KV5.1, kH1
General protein information
Preferred Names
potassium voltage-gated channel subfamily F member 1
Names
potassium voltage-gated channel subfamily F member 1
potassium channel KH1
potassium channel Kv5.1
voltage-gated potassium channel subunit Kv5.1
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

2

2p25

Summary Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily F. This gene is intronless and expressed in all tissues tested, including the heart, skeletal muscle, brain, kidney, and pancreas. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

603787

Disorder Html:





The following KCNF1 gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the KCNF1 gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu31247 NM_002236 Homo sapiens potassium channel, voltage gated modifier subfamily F, member 1 (KCNF1), mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $319

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu31247
Accession Version NM_002236.4 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1485bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 18-JAN-2015
Organism Homo sapiens (human)
Product potassium voltage-gated channel subfamily F member 1
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC026110.2. On Dec 31, 2002 this sequence version replaced gi:21314779. Summary: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily F. This gene is intronless and expressed in all tissues tested, including the heart, skeletal muscle, brain, kidney, and pancreas. [provided by RefSeq, Jul 2008]. ##Evidence-Data-START## Transcript exon combination :: BC026110.2 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
ATGGACGGGT CCGGGGAGCG CAGCCTCCCG GAGCCGGGCA GCCAGAGCTC CGCTGCCAGC 
GACGACATAG AGATAGTCGT CAACGTGGGG GGCGTGCGGC AGGTGCTGTA CGGGGACCTC
CTCAGTCAGT ACCCTGAGAC CCGGCTGGCG GAGCTCATCA ACTGCTTGGC TGGGGGCTAC
GACACCATCT TCTCCCTGTG CGACGACTAC GACCCCGGCA AGCGCGAGTT CTACTTTGAC
AGGGACCCGG ACGCCTTCAA GTGTGTCATC GAGGTGTACT ATTTCGGGGA GGTCCACATG
AAGAAGGGCA TCTGCCCCAT CTGCTTCAAG AACGAGATGG ACTTCTGGAA GGTGGACCTC
AAGTTCCTGG ACGACTGTTG CAAGAGCCAC CTGAGCGAGA AGCGCGAGGA GCTGGAGGAG
ATCGCGCGCC GCGTGCAGCT CATCCTGGAC GACCTGGGCG TGGACGCAGC CGAGGGCCGC
TGGCGCCGCT GCCAGAAGTG CGTCTGGAAG TTCCTGGAGA AGCCCGAGTC GTCGTGCCCG
GCGCGGGTGG TGGCCGTGCT CTCCTTCCTG CTCATCCTCG TCTCGTCCGT GGTCATGTGC
ATGGGCACCA TCCCCGAGCT GCAGGTGCTG GACGCCGAGG GCAACCGCGT GGAGCACCCG
ACGCTGGAGA ACGTGGAGAC GGCGTGCATT GGCTGGTTCA CCCTGGAGTA CCTGCTGCGC
CTCTTCTCGT CACCCAACAA GCTGCACTTC GCGCTGTCCT TCATGAACAT TGTGGACGTG
CTGGCCATCC TCCCCTTCTA CGTGAGCCTC ACGCTCACGC ACCTGGGTGC CCGCATGATG
GAGCTGACCA ACGTGCAGCA GGCCGTGCAG GCGCTGCGGA TCATGCGCAT CGCGCGCATC
TTCAAGCTGG CCCGCCACTC CTCGGGCCTG CAGACCCTCA CCTATGCCCT CAAGCGCAGC
TTCAAGGAAC TGGGGCTGCT GCTCATGTAC CTGGCAGTGG GTATCTTCGT CTTCTCTGCC
CTGGGCTACA CCATGGAGCA GAGCCATCCA GAGACCCTGT TTAAGAGCAT CCCCCAGTCC
TTCTGGTGGG CCATCATCAC CATGACCACC GTCGGCTACG GCGACATCTA CCCCAAGACC
ACGCTGGGCA AGCTCAACGC GGCCATCAGC TTCTTGTGTG GTGTCATCGC CATCGCCCTG
CCCATCCACC CCATCATCAA CAACTTTGTC AGGTACTACA ACAAGCAGCG CGTCCTGGAG
ACCGCGGCCA AGCACGAGCT GGAGCTGATG GAACTCAACT CCAGCAGCGG GGGCGAGGGC
AAGACCGGGG GCTCCCGCAG TGACCTGGAC AACCTCCCTC CAGAGCCTGC GGGGAAGGAG
GCGCCGAGCT GCAGCAGCCG GCTGAAGCTC TCCCACAGCG ACACCTTCAT CCCCCTCCTG
ACCGAGGAGA AGCACCACAG GACCCGGCTC CAGAGTTGCA AGTGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_002227.2
CDS491..1975
Misc Feature(1)347..349(+)
Misc Feature(2)563..868(+)
Misc Feature(3)1040..1102(+)
Misc Feature(4)1160..1222(+)
Misc Feature(5)1163..1696(+)
Misc Feature(6)1238..1300(+)
Misc Feature(7)1358..1420(+)
Misc Feature(8)1463..1525(+)
Misc Feature(9)1481..1690(+)
Misc Feature(10)1598..1615(+)
Misc Feature(11)1646..1708(+)
Exon (1)1..2289
Gene:KCNF1
Gene Synonym:
Translation
Position Chain Variation Link
57 57 c, g dbSNP:577230482
68 68 c, g dbSNP:373451952
75 75 g, t dbSNP:544697493
80 80 a, t dbSNP:562888983
121 121 g, t dbSNP:530095017
145 145 c, t dbSNP:542276479
159 159 c, t dbSNP:12617163
326 326 c, g dbSNP:528014082
343 343 a, g dbSNP:552768809
437 437 a, g dbSNP:564710821
471 471 a, c dbSNP:544531420
472 472 a, g dbSNP:756420529
489 489 a, g dbSNP:777875492
502 502 c, t dbSNP:754027211
503 503 c, g dbSNP:757361037
510 510 g, t dbSNP:778938776
517 517 a, c dbSNP:746986485
523 523 a, g dbSNP:768572625
527 527 a, g dbSNP:550642036
532 532 c, t dbSNP:747908828
535 535 c, g dbSNP:769564298
549 549 a, g dbSNP:772769148
568 568 a, c dbSNP:147760531
574 574 c, t dbSNP:770616553
577 577 c, g dbSNP:201712383
587 587 a, c dbSNP:760188585
594 594 g, t dbSNP:199875738
596 596 c, g dbSNP:753194893
598 598 g, t dbSNP:146949759
605 605 g, t dbSNP:764481728
619 619 a, g dbSNP:754053913
620 620 c, t dbSNP:757436594
622 622 c, t dbSNP:779026809
626 626 a, g dbSNP:750484493
628 628 a, g dbSNP:758414530
631 631 c, g dbSNP:532816858
639 639 c, g dbSNP:545635060
641 641 a, g dbSNP:141961283
649 649 c, t dbSNP:566398442
653 653 g, t dbSNP:777604028
655 655 c, t dbSNP:748935443
662 662 c, g dbSNP:370503620
671 671 a, g dbSNP:774063812
679 679 c, t dbSNP:199646402
691 691 c, t dbSNP:771646638
694 694 c, t dbSNP:775895732
706 706 c, g, t dbSNP:375600263
707 707 a, g dbSNP:777047131
713 713 a, c dbSNP:762076343
718 718 a, g dbSNP:765454752
738 738 c, t dbSNP:193920977
741 741 a, g dbSNP:750576434
757 757 a, c dbSNP:758502384
763 763 a, g dbSNP:767407657
773 773 c, t dbSNP:766432391
783 783 g, t dbSNP:752626584
790 790 a, g dbSNP:138975329
802 802 c, t dbSNP:777495489
805 805 c, t dbSNP:199752745
850 850 a, c dbSNP:757063577
854 854 c, t dbSNP:778717363
859 859 c, g dbSNP:745480939
862 862 c, t dbSNP:151111224
867 867 c, g dbSNP:771507066
871 871 c, t dbSNP:775030406
875 875 a, g dbSNP:747533084
879 879 a, g dbSNP:201047040
880 880 c, t dbSNP:146303502
885 885 a, g dbSNP:776941951
889 889 a, g dbSNP:762168780
895 895 a, c, t dbSNP:766200572
896 896 a, g dbSNP:773444645
913 913 c, t dbSNP:763139502
916 916 g, t dbSNP:766410972
920 920 c, t dbSNP:751654561
922 922 c, t dbSNP:751695475
923 923 a, g dbSNP:764108317
931 931 c, t dbSNP:754950294
940 940 c, t dbSNP:757151428
943 943 c, t dbSNP:778805573
944 944 c, g dbSNP:142872443
946 946 a, g dbSNP:368995113
949 949 a, c dbSNP:373432598
950 950 a, g, t dbSNP:779483984
956 956 a, g dbSNP:767981110
958 958 a, g dbSNP:3732104
959 959 a, g dbSNP:748605697
961 961 c, t dbSNP:770192134
962 962 a, g dbSNP:773536391
964 964 g, t dbSNP:763151198
965 965 a, g dbSNP:771173964
974 974 a, c dbSNP:774379834
977 977 a, c dbSNP:759669416
981 981 g, t dbSNP:767457391
988 988 g, t dbSNP:753853334
1015 1015 c, g, t dbSNP:761824284
1018 1018 a, g dbSNP:531489171
1021 1021 a, g dbSNP:760480871
1028 1028 c, t dbSNP:779758113
1033 1033 a, g dbSNP:751131229
1035 1035 a, g dbSNP:537683504
1045 1045 c, g, t dbSNP:374798024
1051 1051 c, g dbSNP:141118481
1063 1063 c, t dbSNP:770281946
1069 1069 c, t dbSNP:778168330
1074 1074 c, t dbSNP:749678874
1075 1075 g, t dbSNP:771134990
1079 1079 g, t dbSNP:774668289
1081 1081 g, t dbSNP:759631101
1103 1103 c, g dbSNP:772331557
1105 1105 c, g, t dbSNP:775683846
1115 1115 a, g dbSNP:765275954
1126 1126 c, t dbSNP:750317475
1138 1138 c, t dbSNP:762835101
1139 1139 a, g dbSNP:147777200
1153 1153 a, g dbSNP:751271962
1154 1154 a, c dbSNP:754554904
1156 1156 a, g dbSNP:780748623
1170 1170 c, g dbSNP:752190108
1187 1187 g, t dbSNP:755564874
1192 1192 a, c dbSNP:778258235
1193 1193 a, c dbSNP:749721460
1201 1201 c, t dbSNP:771351917
1213 1213 c, t dbSNP:141086439
1219 1219 a, g dbSNP:779129304
1242 1242 c, t dbSNP:746144615
1244 1244 c, t dbSNP:34752664
1249 1249 c, g dbSNP:775792216
1261 1261 c, t dbSNP:747088045
1267 1267 c, t dbSNP:199507399
1268 1268 a, g dbSNP:773222597
1270 1270 a, g dbSNP:762775819
1291 1291 c, t dbSNP:114664009
1297 1297 c, t dbSNP:774011788
1298 1298 c, t dbSNP:759245380
1306 1306 c, g, t dbSNP:560494220
1313 1313 c, t dbSNP:755654460
1314 1314 c, t dbSNP:763548688
1322 1322 c, t dbSNP:754419690
1342 1342 a, c dbSNP:757678960
1345 1345 g, t dbSNP:779404957
1350 1350 a, g dbSNP:371877225
1354 1354 a, c, t dbSNP:202046685
1355 1355 g, t dbSNP:747176275
1360 1360 a, g dbSNP:367858044
1362 1362 a, c dbSNP:768905247
1363 1363 c, g dbSNP:753781334
1364 1364 c, t dbSNP:776540686
1368 1368 a, g dbSNP:749314936
1381 1381 c, t dbSNP:559871658
1419 1419 g, t dbSNP:774286794
1423 1423 a, g dbSNP:759333131
1432 1432 a, c dbSNP:145867221
1444 1444 a, g dbSNP:775148362
1445 1445 a, c dbSNP:760300320
1447 1447 c, t dbSNP:763704723
1454 1454 a, c dbSNP:753288456
1463 1463 a, g dbSNP:756730123
1465 1465 g, t dbSNP:765663120
1474 1474 c, t dbSNP:750899294
1476 1476 c, t dbSNP:201163636
1513 1513 a, g dbSNP:780542641
1523 1523 a, c dbSNP:747274004
1531 1531 c, g dbSNP:755245489
1542 1542 a, g dbSNP:781391412
1543 1543 a, g dbSNP:748191250
1557 1557 a, g dbSNP:1046004
1564 1564 c, t dbSNP:769845783
1591 1591 c, t dbSNP:778749048
1600 1600 a, c dbSNP:745758930
1603 1603 c, t dbSNP:771906770
1609 1609 c, t dbSNP:775238006
1615 1615 c, t dbSNP:760390150
1633 1633 a, c, g dbSNP:768185167
1637 1637 a, g dbSNP:1046005
1650 1650 c, t dbSNP:761257487
1651 1651 a, g dbSNP:200755867
1666 1666 c, g dbSNP:751013676
1669 1669 c, t dbSNP:763520542
1678 1678 c, t dbSNP:3732105
1706 1706 a, g dbSNP:749594660
1714 1714 c, t dbSNP:751957735
1739 1739 c, t dbSNP:755311321
1742 1742 a, g dbSNP:372097411
1750 1750 g, t dbSNP:201734044
1753 1753 c, g, t dbSNP:144040411
1754 1754 a, g dbSNP:745849015
1755 1755 c, t dbSNP:771996767
1756 1756 a, g dbSNP:562576257
1761 1761 a, g dbSNP:746807169
1765 1765 c, t dbSNP:768454594
1768 1768 a, g dbSNP:61741190
1788 1788 a, g dbSNP:761502406
1793 1793 a, g dbSNP:769225801
1798 1798 c, t dbSNP:139764455
1801 1801 c, g dbSNP:772843140
1803 1803 a, g dbSNP:763611972
1804 1804 c, t dbSNP:377006729
1807 1807 c, g dbSNP:752047195
1811 1811 a, g dbSNP:759849978
1813 1813 c, g dbSNP:369851909
1816 1816 c, g dbSNP:752912706
1820 1820 c, g dbSNP:756330748
1824 1824 c, t dbSNP:777899692
1826 1826 c, g, t dbSNP:373365915
1827 1827 a, g dbSNP:779994024
1830 1830 a, g dbSNP:199981711
1846 1846 c, t dbSNP:746912773
1850 1850 c, t dbSNP:768095681
1852 1852 a, g dbSNP:781007640
1860 1860 c, t dbSNP:374035056
1861 1861 a, g dbSNP:115526526
1862 1862 g, t dbSNP:772941611
1864 1864 a, g dbSNP:35701651
1868 1868 a, g dbSNP:770524900
1872 1872 c, g, t dbSNP:149685660
1873 1873 a, g dbSNP:769402627
1875 1875 c, g, t dbSNP:140683647
1876 1876 a, g dbSNP:764318856
1880 1880 a, t dbSNP:754016090
1882 1882 c, t dbSNP:757347961
1883 1883 a, g dbSNP:376778174
1889 1889 c, t dbSNP:765274857
1890 1890 a, g dbSNP:751488924
1893 1893 c, t dbSNP:570687002
1910 1910 g, t dbSNP:754937034
1914 1914 a, c dbSNP:780905302
1919 1919 a, g dbSNP:747988017
1924 1924 c, g dbSNP:755905912
1933 1933 a, c, t dbSNP:200816549
1934 1934 a, g, t dbSNP:138500972
1947 1947 a, g dbSNP:746431553
1948 1948 c, t dbSNP:538021458
1966 1966 c, t dbSNP:775806040
1976 1976 c, t dbSNP:773104141
1978 1978 a, g dbSNP:201608690
1979 1979 a, g dbSNP:200541883
1982 1982 a, g dbSNP:776884076
1984 1984 c, t dbSNP:137856028
1987 1987 -, c dbSNP:35199085
1990 1990 a, g dbSNP:766348577
1999 1999 c, t dbSNP:750501152
2008 2008 c, t dbSNP:758351477
2009 2009 a, g dbSNP:767493587
2012 2012 a, g dbSNP:554160650
2014 2014 a, c, g dbSNP:755995918
2019 2019 c, t dbSNP:753586198
2022 2022 a, g dbSNP:774101829
2027 2027 c, t dbSNP:141969545
2065 2065 c, t dbSNP:759535926
2071 2071 a, c dbSNP:545913143
2109 2109 c, t dbSNP:564779846
2113 2113 c, t dbSNP:576686144
2120 2120 c, g dbSNP:2602169
2121 2121 c, g dbSNP:2602170
2162 2162 a, g dbSNP:543961546
2179 2179 g, t dbSNP:561957821
2189 2189 a, g dbSNP:562909892
2199 2199 c, t dbSNP:529696125
2209 2209 a, g dbSNP:547524133
2219 2219 c, t dbSNP:186500057
2220 2220 a, g dbSNP:41264189
2221 2221 c, t dbSNP:559857673
2222 2222 a, g dbSNP:527261560
2227 2227 c, g dbSNP:551911687
2247 2247 c, t dbSNP:570695821
2249 2249 a, c dbSNP:145835440
2250 2250 a, g dbSNP:59620674
2262 2262 c, t dbSNP:568263806
2275 2275 c, g, t dbSNP:752795342
2281 2281 c, t dbSNP:535693643

Target ORF information:

RefSeq Version NM_002236
Organism Homo sapiens (human)
Definition Homo sapiens potassium channel, voltage gated modifier subfamily F, member 1 (KCNF1), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_002236

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
ATGGACGGGT CCGGGGAGCG CAGCCTCCCG GAGCCGGGCA GCCAGAGCTC CGCTGCCAGC 
GACGACATAG AGATAGTCGT CAACGTGGGG GGCGTGCGGC AGGTGCTGTA CGGGGACCTC
CTCAGTCAGT ACCCTGAGAC CCGGCTGGCG GAGCTCATCA ACTGCTTGGC TGGGGGCTAC
GACACCATCT TCTCCCTGTG CGACGACTAC GACCCCGGCA AGCGCGAGTT CTACTTTGAC
AGGGACCCGG ACGCCTTCAA GTGTGTCATC GAGGTGTACT ATTTCGGGGA GGTCCACATG
AAGAAGGGCA TCTGCCCCAT CTGCTTCAAG AACGAGATGG ACTTCTGGAA GGTGGACCTC
AAGTTCCTGG ACGACTGTTG CAAGAGCCAC CTGAGCGAGA AGCGCGAGGA GCTGGAGGAG
ATCGCGCGCC GCGTGCAGCT CATCCTGGAC GACCTGGGCG TGGACGCAGC CGAGGGCCGC
TGGCGCCGCT GCCAGAAGTG CGTCTGGAAG TTCCTGGAGA AGCCCGAGTC GTCGTGCCCG
GCGCGGGTGG TGGCCGTGCT CTCCTTCCTG CTCATCCTCG TCTCGTCCGT GGTCATGTGC
ATGGGCACCA TCCCCGAGCT GCAGGTGCTG GACGCCGAGG GCAACCGCGT GGAGCACCCG
ACGCTGGAGA ACGTGGAGAC GGCGTGCATT GGCTGGTTCA CCCTGGAGTA CCTGCTGCGC
CTCTTCTCGT CACCCAACAA GCTGCACTTC GCGCTGTCCT TCATGAACAT TGTGGACGTG
CTGGCCATCC TCCCCTTCTA CGTGAGCCTC ACGCTCACGC ACCTGGGTGC CCGCATGATG
GAGCTGACCA ACGTGCAGCA GGCCGTGCAG GCGCTGCGGA TCATGCGCAT CGCGCGCATC
TTCAAGCTGG CCCGCCACTC CTCGGGCCTG CAGACCCTCA CCTATGCCCT CAAGCGCAGC
TTCAAGGAAC TGGGGCTGCT GCTCATGTAC CTGGCAGTGG GTATCTTCGT CTTCTCTGCC
CTGGGCTACA CCATGGAGCA GAGCCATCCA GAGACCCTGT TTAAGAGCAT CCCCCAGTCC
TTCTGGTGGG CCATCATCAC CATGACCACC GTCGGCTACG GCGACATCTA CCCCAAGACC
ACGCTGGGCA AGCTCAACGC GGCCATCAGC TTCTTGTGTG GTGTCATCGC CATCGCCCTG
CCCATCCACC CCATCATCAA CAACTTTGTC AGGTACTACA ACAAGCAGCG CGTCCTGGAG
ACCGCGGCCA AGCACGAGCT GGAGCTGATG GAACTCAACT CCAGCAGCGG GGGCGAGGGC
AAGACCGGGG GCTCCCGCAG TGACCTGGAC AACCTCCCTC CAGAGCCTGC GGGGAAGGAG
GCGCCGAGCT GCAGCAGCCG GCTGAAGCTC TCCCACAGCG ACACCTTCAT CCCCCTCCTG
ACCGAGGAGA AGCACCACAG GACCCGGCTC CAGAGTTGCA AGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.