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KCNJ11 cDNA ORF clone, Homo sapiens (human)

Gene Symbol KCNJ11
Entrez Gene ID 3767
Full Name potassium channel, inwardly rectifying subfamily J, member 11
Synonyms BIR, HHF2, IKATP, KIR6.2, MODY13, PHHI, TNDM3
General protein information
Preferred Names
ATP-sensitive inward rectifier potassium channel 11
Names
ATP-sensitive inward rectifier potassium channel 11
beta-cell inward rectifier subunit
inward rectifier K(+) channel Kir6.2
inwardly rectifying potassium channel KIR6.2
potassium channel inwardly rectifing subfamily J member 11
potassium channel, inwardly rectifying subfamily J member 11
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

11

11p15.1

Summary Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and is found associated with the sulfonylurea receptor SUR. Mutations in this gene are a cause of familial persistent hyperinsulinemic hypoglycemia of infancy (PHHI), an autosomal recessive disorder characterized by unregulated insulin secretion. Defects in this gene may also contribute to autosomal dominant non-insulin-dependent diabetes mellitus type II (NIDDM), transient neonatal diabetes mellitus type 3 (TNDM3), and permanent neonatal diabetes mellitus (PNDM). Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Oct 2009]. lac of sum
Disorder MIM:

600937

Disorder Html: Hyperinsulinemic hypoglycemia, familial, 2, 601820 (3);





The following KCNJ11 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the KCNJ11 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu19078 NM_000525 Homo sapiens potassium channel, inwardly rectifying subfamily J, member 11 (KCNJ11), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $319.00
OHu20898 XM_006718226 PREDICTED: Homo sapiens potassium channel, inwardly rectifying subfamily J, member 11 (KCNJ11), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $199.00
OHu20898 NM_001166290 Homo sapiens potassium channel, inwardly rectifying subfamily J, member 11 (KCNJ11), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $199.00

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu19078
Accession Version NM_000525.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1173bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 18-JAN-2015
Organism Homo sapiens (human)
Product ATP-sensitive inward rectifier potassium channel 11 isoform 1
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC124798.5 and AI377272.1. This sequence is a reference standard in the RefSeqGene project. On Apr 7, 2005 this sequence version replaced gi:25777631. Summary: Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and is found associated with the sulfonylurea receptor SUR. Mutations in this gene are a cause of familial persistent hyperinsulinemic hypoglycemia of infancy (PHHI), an autosomal recessive disorder characterized by unregulated insulin secretion. Defects in this gene may also contribute to autosomal dominant non-insulin-dependent diabetes mellitus type II (NIDDM), transient neonatal diabetes mellitus type 3 (TNDM3), and permanent neonatal diabetes mellitus (PNDM). Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Oct 2009]. Transcript Variant: This variant (1) encodes the longer protein (isoform 1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. COMPLETENESS: full length.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
ATGCTGTCCC GCAAGGGCAT CATCCCCGAG GAATACGTGC TGACACGCCT GGCAGAGGAC 
CCTGCCAAGC CCAGGTACCG TGCCCGCCAG CGGAGGGCCC GCTTTGTGTC CAAGAAAGGC
AACTGCAACG TGGCCCACAA GAACATCCGG GAGCAGGGCC GCTTCCTGCA GGACGTGTTC
ACCACGCTGG TGGACCTCAA GTGGCCACAC ACATTGCTCA TCTTCACCAT GTCCTTCCTG
TGCAGCTGGC TGCTCTTCGC CATGGCCTGG TGGCTCATCG CCTTCGCCCA CGGTGACCTG
GCCCCCAGCG AGGGCACTGC TGAGCCCTGT GTCACCAGCA TCCACTCCTT CTCGTCTGCC
TTCCTTTTCT CCATTGAGGT CCAAGTGACT ATTGGCTTTG GGGGGCGCAT GGTGACTGAG
GAGTGCCCAC TGGCCATCCT GATCCTCATC GTGCAGAACA TCGTGGGGCT CATGATCAAC
GCCATCATGC TTGGCTGCAT CTTCATGAAG ACTGCCCAAG CCCACCGCAG GGCTGAGACC
CTCATCTTCA GCAAGCATGC GGTGATCGCC CTGCGCCACG GCCGCCTCTG CTTCATGCTA
CGTGTGGGTG ACCTCCGCAA GAGCATGATC ATCAGCGCCA CCATCCACAT GCAGGTGGTA
CGCAAGACCA CCAGCCCCGA GGGCGAGGTG GTGCCCCTCC ACCAGGTGGA CATCCCCATG
GAGAACGGCG TGGGTGGCAA CAGCATCTTC CTGGTGGCCC CGCTGATCAT CTACCATGTC
ATTGATGCCA ACAGCCCACT CTACGACCTG GCACCCAGCG ACCTGCACCA CCACCAGGAC
CTCGAGATCA TCGTCATCCT GGAAGGCGTG GTGGAAACCA CGGGCATCAC CACCCAGGCC
CGCACCTCCT ACCTGGCCGA TGAGATCCTG TGGGGCCAGC GCTTTGTGCC CATTGTAGCT
GAGGAGGACG GACGTTACTC TGTGGACTAC TCCAAGTTTG GCAACACCGT CAAAGTGCCC
ACACCACTCT GCACGGCCCG CCAGCTTGAT GAGGACCACA GCCTACTGGA AGCTCTGACC
CTCGCCTCAG CCCGCGGGCC CCTGCGCAAG CGCAGCGTGC CCATGGCCAA GGCCAAGCCC
AAGTTCAGCA TCTCTCCAGA TTCCCTGTCC TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqNP_000516.3
CDS569..1741
Misc Feature(1)348..348(+)
Misc Feature(2)500..502(+)
Misc Feature(3)674..1639(+)
Misc Feature(4)773..847(+)
Misc Feature(5)956..973(+)
Misc Feature(6)1001..1066(+)
Misc Feature(7)1046..1048(+)
Misc Feature(8)1589..1591(+)
Misc Feature(9)1721..1723(+)
Exon (1)1..3412
Gene:KCNJ11
Gene Synonym:
Translation
Position Chain Variation Link
10 10 c, g dbSNP:547932593
55 55 -, t dbSNP:397808534
62 62 -, t dbSNP:35513985
62 62 -, t dbSNP:35980606
71 71 c, t dbSNP:529946415
102 102 a, g dbSNP:546262561
128 128 c, t dbSNP:766209300
144 144 c, g dbSNP:5221
176 176 c, t dbSNP:562482477
209 209 c, t dbSNP:762997173
255 255 -, g dbSNP:781416603
336 336 c, t dbSNP:544097908
341 341 a, g dbSNP:372087336
353 353 a, g, t dbSNP:561579833
390 390 c, t dbSNP:776949660
395 395 a, g dbSNP:564864405
415 415 g, t dbSNP:539975714
421 421 g, t dbSNP:572849559
434 434 a, g dbSNP:5220
435 435 g, t dbSNP:387906398
452 452 c, t dbSNP:764833481
484 484 c, t dbSNP:761208553
520 520 a, g, t dbSNP:745454365
523 523 a, g, t dbSNP:756707717
532 532 c, t dbSNP:753392628
533 533 a, g dbSNP:777654385
548 548 c, t dbSNP:756107063
549 549 c, t dbSNP:376226744
559 559 c, t dbSNP:767154821
560 560 a, t dbSNP:759376993
562 562 c, t dbSNP:771347147
563 563 a, g dbSNP:554874150
573 573 c, t dbSNP:193922565
576 576 c, g dbSNP:587783674
578 578 a, c, t dbSNP:543286136
579 579 a, g dbSNP:769283457
595 595 c, t dbSNP:374134161
596 596 a, g dbSNP:587783667
599 599 a, g dbSNP:542961309
604 604 a, c, t dbSNP:104894236
605 605 a, g dbSNP:139079635
613 613 a, t dbSNP:746264957
614 614 c, t dbSNP:778405781
615 615 a, g dbSNP:770609243
621 621 c, g dbSNP:41309072
622 622 a, g dbSNP:193922564
625 625 a, g dbSNP:748791717
634 634 c, t dbSNP:768189518
635 635 a, g dbSNP:5219
647 647 c, t dbSNP:752507753
648 648 a, g dbSNP:774714794
651 651 c, t dbSNP:754683593
653 653 c, t dbSNP:751424820
655 655 c, g, t dbSNP:539327013
659 659 c, t dbSNP:757621300
660 660 a, g dbSNP:571564577
669 669 a, g, t dbSNP:141145502
671 671 c, g, t dbSNP:193929333
672 672 c, t dbSNP:41314517
676 676 a, g dbSNP:112070496
692 692 c, t dbSNP:80356610
693 693 g, t dbSNP:534808921
715 715 c, g dbSNP:768117265
717 717 a, c, g dbSNP:80356611
723 723 a, g dbSNP:193929337
725 725 a, c, g dbSNP:80356613
726 726 a, g dbSNP:80356615
728 728 c, t dbSNP:375848765
729 729 a, g dbSNP:587783666
743 743 a, g dbSNP:80356616
744 744 g, t dbSNP:80356617
746 746 c, t dbSNP:770553801
747 747 a, t dbSNP:387906783
754 754 a, g dbSNP:748877741
758 758 g, t dbSNP:115716690
760 760 a, g dbSNP:769251241
764 764 c, t dbSNP:771238609
769 769 c, g dbSNP:747719667
773 773 a, c dbSNP:372565142
778 778 a, c dbSNP:749829780
782 782 a, t dbSNP:754986446
789 789 c, t dbSNP:746779073
807 807 c, t dbSNP:780053755
818 818 c, t dbSNP:758281673
826 826 c, t dbSNP:754048558
827 827 a, g dbSNP:764444072
830 830 a, t dbSNP:756124560
844 844 c, t dbSNP:752859952
847 847 c, t dbSNP:142577961
848 848 a, g dbSNP:138065534
853 853 c, t dbSNP:774849547
854 854 a, g dbSNP:766658650
859 859 a, c, t dbSNP:371886780
861 861 a, g dbSNP:769538059
866 866 -, c dbSNP:767164487
871 871 c, t dbSNP:747582437
874 874 c, t dbSNP:776275457
876 876 g, t dbSNP:200932525
877 877 a, c, t dbSNP:376773562
878 878 a, g dbSNP:145429555
893 893 a, c dbSNP:758228551
902 902 a, g dbSNP:745705365
905 905 a, g dbSNP:778108404
912 912 a, g dbSNP:374334444
913 913 c, t dbSNP:769962094
918 918 -, tct dbSNP:757062550
921 921 c, t dbSNP:756424776
922 922 a, g dbSNP:140636367
923 923 g, t dbSNP:781271888
972 972 a, g dbSNP:755013629
973 973 -, g dbSNP:557160758
973 973 g, t dbSNP:752018515
974 974 c, t dbSNP:766891274
979 979 a, g dbSNP:371977895
1008 1008 c, t dbSNP:28936678
1015 1015 c, t dbSNP:764796514
1018 1018 c, t dbSNP:761588360
1019 1019 a, g dbSNP:529884745
1030 1030 c, t dbSNP:145757832
1031 1031 a, g dbSNP:587783668
1036 1036 a, g dbSNP:748158864
1039 1039 c, t dbSNP:116045724
1048 1048 c, t dbSNP:568688504
1061 1061 a, g dbSNP:775520445
1065 1065 a, g, t dbSNP:80356618
1066 1066 c, g dbSNP:587783669
1067 1067 a, c dbSNP:80356620
1077 1077 a, g dbSNP:80356621
1078 1078 c, g dbSNP:80356622
1089 1089 c, g dbSNP:587783670
1094 1094 c, t dbSNP:201264306
1100 1100 a, g dbSNP:745652318
1104 1104 a, c dbSNP:587783671
1108 1108 c, g dbSNP:778825557
1112 1112 a, g dbSNP:193929348
1135 1135 a, c, t dbSNP:114899765
1136 1136 a, c, g dbSNP:77131926
1138 1138 a, c, t dbSNP:5218
1142 1142 c, t dbSNP:780511484
1143 1143 a, g, t dbSNP:750778014
1146 1146 a, g dbSNP:373657240
1147 1147 c, t dbSNP:762089425
1151 1151 c, t dbSNP:753491511
1152 1152 a, g dbSNP:5217
1168 1168 a, t dbSNP:760229694
1169 1169 c, t dbSNP:80356625
1170 1170 a, g, t dbSNP:80356624
1180 1180 a, c dbSNP:577757932
1184 1184 c, t dbSNP:775204908
1189 1189 a, g dbSNP:772121211
1204 1204 c, t dbSNP:759487287
1218 1218 c, t dbSNP:774156815
1223 1223 g, t dbSNP:371633969
1229 1229 a, c, t dbSNP:781450902
1230 1230 a, g dbSNP:768909861
1232 1232 a, c dbSNP:747090537
1236 1236 c, t dbSNP:561086953
1237 1237 c, g dbSNP:780169484
1246 1246 c, t dbSNP:74162102
1247 1247 a, g dbSNP:587783672
1250 1250 a, g dbSNP:147937000
1252 1252 c, t dbSNP:746308356
1253 1253 a, g dbSNP:587783673
1258 1258 a, g dbSNP:779320079
1268 1268 c, t dbSNP:757593972
1276 1276 a, g dbSNP:754205539
1288 1288 c, g dbSNP:368520582
1294 1294 c, t dbSNP:72554078
1297 1297 c, t dbSNP:752411054
1298 1298 a, g dbSNP:751772105
1301 1301 g, t dbSNP:199848733
1313 1313 a, g dbSNP:375200088
1321 1321 c, g dbSNP:370638485
1323 1323 c, t dbSNP:193929352
1327 1327 c, g, t dbSNP:772950264
1329 1329 c, t dbSNP:104894237
1330 1330 a, g dbSNP:761931092
1340 1340 c, t dbSNP:747180509
1341 1341 a, g dbSNP:775698456
1344 1344 a, g dbSNP:104894248
1348 1348 c, t dbSNP:745958766
1356 1356 a, c dbSNP:779455025
1366 1366 a, g dbSNP:376027906
1369 1369 c, g dbSNP:5216
1372 1372 c, t dbSNP:778225010
1373 1373 a, g dbSNP:756552714
1376 1376 a, c, g dbSNP:1800467
1381 1381 -, t dbSNP:764143976
1381 1381 a, t dbSNP:754512091
1385 1385 a, g dbSNP:751068069
1387 1387 c, t dbSNP:202238153
1388 1388 a, g, t dbSNP:773218695
1395 1395 a, c dbSNP:113498300
1396 1396 c, t dbSNP:764950479
1399 1399 c, t dbSNP:761628495
1411 1411 c, t dbSNP:116392938
1412 1412 a, g dbSNP:267607196
1417 1417 c, t dbSNP:745931687
1420 1420 a, c, t dbSNP:1800854
1421 1421 a, g dbSNP:149667199
1435 1435 c, t dbSNP:573946686
1436 1436 a, g, t dbSNP:750414160
1438 1438 c, g dbSNP:201379919
1449 1449 c, t dbSNP:780957825
1450 1450 a, g dbSNP:115585638
1454 1454 a, c, g dbSNP:193929353
1468 1468 c, t dbSNP:751069491
1469 1469 c, t dbSNP:377091338
1470 1470 a, g, t dbSNP:74339576
1471 1471 c, t dbSNP:200855007
1473 1473 c, t dbSNP:761575495
1480 1480 c, g, t dbSNP:372471215
1482 1482 c, t dbSNP:759618669
1486 1486 c, t dbSNP:377040874
1487 1487 a, g dbSNP:770875360
1495 1495 a, c dbSNP:372180195
1502 1502 a, g dbSNP:72554079
1504 1504 c, t dbSNP:139445409
1508 1508 c, t dbSNP:748516747
1509 1509 a, g dbSNP:145935651
1520 1520 a, g dbSNP:369179692
1532 1532 a, g dbSNP:193929355
1534 1534 a, g dbSNP:746578913
1541 1541 a, c, t dbSNP:550315112
1542 1542 a, c, g dbSNP:778793458
1546 1546 c, t dbSNP:757254860
1556 1556 c, t dbSNP:587783675
1557 1557 a, g dbSNP:193929356
1558 1558 c, t dbSNP:753784994
1560 1560 c, g dbSNP:763728797
1565 1565 a, t dbSNP:193929357
1569 1569 a, g dbSNP:193929358
1576 1576 a, c, t dbSNP:538566992
1577 1577 a, g dbSNP:5215
1584 1584 g, t dbSNP:138125678
1585 1585 a, g, t dbSNP:770408379
1599 1599 g, t dbSNP:762355661
1602 1602 a, c, t dbSNP:114215135
1603 1603 a, g dbSNP:747426640
1607 1607 c, t dbSNP:146255794
1608 1608 a, g dbSNP:771797701
1612 1612 c, g dbSNP:745379486
1614 1614 c, t dbSNP:761453394
1619 1619 a, g dbSNP:778334034
1626 1626 a, g dbSNP:756762581
1628 1628 a, g dbSNP:749183151
1645 1645 a, g dbSNP:777788092
1652 1652 a, g dbSNP:755839409
1656 1656 c, t dbSNP:375859605
1657 1657 a, g dbSNP:5214
1661 1661 c, t dbSNP:758749160
1662 1662 a, g dbSNP:750689750
1663 1663 c, t dbSNP:143276279
1664 1664 a, g dbSNP:149141985
1667 1667 -, c dbSNP:35043381
1667 1667 c, t dbSNP:138168190
1673 1673 a, c, t dbSNP:371275937
1674 1674 a, g dbSNP:114613745
1679 1679 c, t dbSNP:771613078
1684 1684 c, t dbSNP:753294641
1685 1685 a, c, g dbSNP:770375846
1688 1688 c, t dbSNP:748841051
1691 1691 a, g dbSNP:777540229
1711 1711 -, cccaag dbSNP:775746898
1711 1711 a, g dbSNP:8175351
1718 1718 a, c, g dbSNP:141904039
1719 1719 a, t dbSNP:557050704
1720 1720 c, t dbSNP:184094021
1722 1722 c, g, t dbSNP:41282930
1727 1727 a, c, g dbSNP:753994346
1728 1728 a, g dbSNP:764508494
1754 1754 c, t dbSNP:560039845
1755 1755 a, g dbSNP:375713439
1760 1760 c, t dbSNP:767827389
1763 1763 a, c dbSNP:759913615
1767 1767 -, a dbSNP:765360093
1767 1767 c, t dbSNP:773965960
1768 1768 a, g dbSNP:770610826
1769 1769 c, t dbSNP:372394648
1770 1770 a, g dbSNP:370047076
1772 1772 a, g dbSNP:199834960
1775 1775 -, tacacac dbSNP:759640892
1777 1777 c, g dbSNP:748053505
1779 1779 c, g dbSNP:555307205
1780 1780 a, g dbSNP:768523190
1781 1781 c, t dbSNP:746850899
1782 1782 a, g dbSNP:775088753
1784 1784 a, c, g dbSNP:757623564
1788 1788 c, t dbSNP:753852754
1792 1792 a, g dbSNP:777853627
1803 1803 a, g, t dbSNP:5213
1806 1806 c, t dbSNP:557821086
1817 1817 a, g dbSNP:193076739
1833 1833 c, t dbSNP:5212
1849 1849 a, c dbSNP:139391954
1866 1866 a, g dbSNP:763277868
1902 1902 c, g dbSNP:77674298
1913 1913 a, c dbSNP:5211
1914 1914 a, c dbSNP:567290120
1953 1953 a, g dbSNP:115811959
1956 1956 c, t dbSNP:5210
1981 1981 a, g dbSNP:770194798
2005 2005 a, g dbSNP:185542065
2028 2028 c, t dbSNP:113019623
2029 2029 a, g dbSNP:5209
2060 2060 c, g dbSNP:533601283
2069 2069 c, t dbSNP:748617845
2076 2076 c, t dbSNP:118179872
2077 2077 a, g dbSNP:541725017
2078 2078 a, g dbSNP:372737066
2100 2100 c, t dbSNP:529498937
2101 2101 a, g dbSNP:561755715
2117 2117 c, t dbSNP:5208
2144 2144 a, g dbSNP:576026175
2175 2175 a, t dbSNP:148712397
2177 2177 -, g dbSNP:35294169
2182 2182 c, t dbSNP:2285676
2197 2197 c, t dbSNP:369186082
2228 2228 a, g dbSNP:79457490
2269 2269 c, t dbSNP:377292224
2270 2270 a, g dbSNP:115826080
2296 2296 g, t dbSNP:771668899
2299 2299 c, g dbSNP:534917931
2305 2305 c, t dbSNP:567523345
2306 2306 a, g dbSNP:555689354
2320 2320 a, g dbSNP:745646969
2330 2330 a, g dbSNP:185669328
2331 2331 a, g dbSNP:778704841
2427 2427 a, g dbSNP:147282653
2438 2438 a, g dbSNP:117976105
2442 2442 a, t dbSNP:5207
2457 2457 a, g dbSNP:561545376
2480 2480 a, g dbSNP:543277374
2507 2507 a, g dbSNP:193101892
2568 2568 c, t dbSNP:372655579
2589 2589 a, g dbSNP:5206
2603 2603 g, t dbSNP:547635594
2611 2611 a, g dbSNP:372136553
2641 2641 a, g dbSNP:529436579
2646 2646 a, g dbSNP:186637027
2658 2658 a, g dbSNP:562092401
2730 2730 c, t dbSNP:5205
2756 2756 c, t dbSNP:531631096
2774 2774 c, t dbSNP:564292096
2775 2775 a, g dbSNP:528111410
2776 2776 c, t dbSNP:770375661
2778 2778 g, t dbSNP:767140617
2782 2782 a, g dbSNP:763437250
2795 2795 c, t dbSNP:572399316
2864 2864 g, t dbSNP:553139186
2873 2873 c, g dbSNP:191697899
2879 2879 -, c dbSNP:35749958
2909 2909 a, g dbSNP:182349583
2919 2919 a, g dbSNP:573875884
2922 2922 a, g dbSNP:76774792
2923 2923 a, g dbSNP:74831871
2938 2938 a, g dbSNP:191682072
2969 2969 c, t dbSNP:765576308
3155 3155 c, t dbSNP:762247193
3170 3170 g, t dbSNP:537326228
3296 3296 c, g dbSNP:569535045
3317 3317 a, c dbSNP:569684578
3330 3330 c, t dbSNP:777153571
3344 3344 c, t dbSNP:768897061
3379 3379 g, t dbSNP:781637981
3394 3394 a, c, t dbSNP:563531727

Target ORF information:

RefSeq Version NM_000525
Organism Homo sapiens (human)
Definition Homo sapiens potassium channel, inwardly rectifying subfamily J, member 11 (KCNJ11), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_000525

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
ATGCTGTCCC GCAAGGGCAT CATCCCCGAG GAATACGTGC TGACACGCCT GGCAGAGGAC 
CCTGCCAAGC CCAGGTACCG TGCCCGCCAG CGGAGGGCCC GCTTTGTGTC CAAGAAAGGC
AACTGCAACG TGGCCCACAA GAACATCCGG GAGCAGGGCC GCTTCCTGCA GGACGTGTTC
ACCACGCTGG TGGACCTCAA GTGGCCACAC ACATTGCTCA TCTTCACCAT GTCCTTCCTG
TGCAGCTGGC TGCTCTTCGC CATGGCCTGG TGGCTCATCG CCTTCGCCCA CGGTGACCTG
GCCCCCAGCG AGGGCACTGC TGAGCCCTGT GTCACCAGCA TCCACTCCTT CTCGTCTGCC
TTCCTTTTCT CCATTGAGGT CCAAGTGACT ATTGGCTTTG GGGGGCGCAT GGTGACTGAG
GAGTGCCCAC TGGCCATCCT GATCCTCATC GTGCAGAACA TCGTGGGGCT CATGATCAAC
GCCATCATGC TTGGCTGCAT CTTCATGAAG ACTGCCCAAG CCCACCGCAG GGCTGAGACC
CTCATCTTCA GCAAGCATGC GGTGATCGCC CTGCGCCACG GCCGCCTCTG CTTCATGCTA
CGTGTGGGTG ACCTCCGCAA GAGCATGATC ATCAGCGCCA CCATCCACAT GCAGGTGGTA
CGCAAGACCA CCAGCCCCGA GGGCGAGGTG GTGCCCCTCC ACCAGGTGGA CATCCCCATG
GAGAACGGCG TGGGTGGCAA CAGCATCTTC CTGGTGGCCC CGCTGATCAT CTACCATGTC
ATTGATGCCA ACAGCCCACT CTACGACCTG GCACCCAGCG ACCTGCACCA CCACCAGGAC
CTCGAGATCA TCGTCATCCT GGAAGGCGTG GTGGAAACCA CGGGCATCAC CACCCAGGCC
CGCACCTCCT ACCTGGCCGA TGAGATCCTG TGGGGCCAGC GCTTTGTGCC CATTGTAGCT
GAGGAGGACG GACGTTACTC TGTGGACTAC TCCAAGTTTG GCAACACCGT CAAAGTGCCC
ACACCACTCT GCACGGCCCG CCAGCTTGAT GAGGACCACA GCCTACTGGA AGCTCTGACC
CTCGCCTCAG CCCGCGGGCC CCTGCGCAAG CGCAGCGTGC CCATGGCCAA GGCCAAGCCC
AAGTTCAGCA TCTCTCCAGA TTCCCTGTCC TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu20898
Accession Version XM_006718226.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 912bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product ATP-sensitive inward rectifier potassium channel 11 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_009237.19) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced gi:578820521. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGGCCTGGT GGCTCATCGC CTTCGCCCAC GGTGACCTGG CCCCCAGCGA GGGCACTGCT 
GAGCCCTGTG TCACCAGCAT CCACTCCTTC TCGTCTGCCT TCCTTTTCTC CATTGAGGTC
CAAGTGACTA TTGGCTTTGG GGGGCGCATG GTGACTGAGG AGTGCCCACT GGCCATCCTG
ATCCTCATCG TGCAGAACAT CGTGGGGCTC ATGATCAACG CCATCATGCT TGGCTGCATC
TTCATGAAGA CTGCCCAAGC CCACCGCAGG GCTGAGACCC TCATCTTCAG CAAGCATGCG
GTGATCGCCC TGCGCCACGG CCGCCTCTGC TTCATGCTAC GTGTGGGTGA CCTCCGCAAG
AGCATGATCA TCAGCGCCAC CATCCACATG CAGGTGGTAC GCAAGACCAC CAGCCCCGAG
GGCGAGGTGG TGCCCCTCCA CCAGGTGGAC ATCCCCATGG AGAACGGCGT GGGTGGCAAC
AGCATCTTCC TGGTGGCCCC GCTGATCATC TACCATGTCA TTGATGCCAA CAGCCCACTC
TACGACCTGG CACCCAGCGA CCTGCACCAC CACCAGGACC TCGAGATCAT CGTCATCCTG
GAAGGCGTGG TGGAAACCAC GGGCATCACC ACCCAGGCCC GCACCTCCTA CCTGGCCGAT
GAGATCCTGT GGGGCCAGCG CTTTGTGCCC ATTGTAGCTG AGGAGGACGG ACGTTACTCT
GTGGACTACT CCAAGTTTGG CAACACCGTC AAAGTGCCCA CACCACTCTG CACGGCCCGC
CAGCTTGATG AGGACCACAG CCTACTGGAA GCTCTGACCC TCGCCTCAGC CCGCGGGCCC
CTGCGCAAGC GCAGCGTGCC CATGGCCAAG GCCAAGCCCA AGTTCAGCAT CTCTCCAGAT
TCCCTGTCCT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqXP_006718289.1
CDS326..1237
Misc Feature(1)326..1135(+)
Translation
Position Chain Variation Link
90 90 c, t dbSNP:377329470
261 261 c, g dbSNP:777230765
291 291 a, g dbSNP:569534291
294 294 c, g dbSNP:61880301
297 297 a, g dbSNP:149028222
299 299 a, g dbSNP:747347825
314 314 c, t dbSNP:758281673
322 322 c, t dbSNP:754048558
323 323 a, g dbSNP:764444072
326 326 a, t dbSNP:756124560
340 340 c, t dbSNP:752859952
343 343 c, t dbSNP:142577961
344 344 a, g dbSNP:138065534
349 349 c, t dbSNP:774849547
350 350 a, g dbSNP:766658650
355 355 a, c, t dbSNP:371886780
357 357 a, g dbSNP:769538059
362 362 -, c dbSNP:767164487
367 367 c, t dbSNP:747582437
370 370 c, t dbSNP:776275457
372 372 g, t dbSNP:200932525
373 373 a, c, t dbSNP:376773562
374 374 a, g dbSNP:145429555
389 389 a, c dbSNP:758228551
398 398 a, g dbSNP:745705365
401 401 a, g dbSNP:778108404
408 408 a, g dbSNP:374334444
409 409 c, t dbSNP:769962094
414 414 -, tct dbSNP:757062550
417 417 c, t dbSNP:756424776
418 418 a, g dbSNP:140636367
419 419 g, t dbSNP:781271888
468 468 a, g dbSNP:755013629
469 469 -, g dbSNP:557160758
469 469 g, t dbSNP:752018515
470 470 c, t dbSNP:766891274
475 475 a, g dbSNP:371977895
504 504 c, t dbSNP:28936678
511 511 c, t dbSNP:764796514
514 514 c, t dbSNP:761588360
515 515 a, g dbSNP:529884745
526 526 c, t dbSNP:145757832
527 527 a, g dbSNP:587783668
532 532 a, g dbSNP:748158864
535 535 c, t dbSNP:116045724
544 544 c, t dbSNP:568688504
557 557 a, g dbSNP:775520445
561 561 a, g, t dbSNP:80356618
562 562 c, g dbSNP:587783669
563 563 a, c dbSNP:80356620
573 573 a, g dbSNP:80356621
574 574 c, g dbSNP:80356622
585 585 c, g dbSNP:587783670
590 590 c, t dbSNP:201264306
596 596 a, g dbSNP:745652318
600 600 a, c dbSNP:587783671
604 604 c, g dbSNP:778825557
608 608 a, g dbSNP:193929348
631 631 a, c, t dbSNP:114899765
632 632 a, c, g dbSNP:77131926
634 634 a, c, t dbSNP:5218
638 638 c, t dbSNP:780511484
639 639 a, g, t dbSNP:750778014
642 642 a, g dbSNP:373657240
643 643 c, t dbSNP:762089425
647 647 c, t dbSNP:753491511
648 648 a, g dbSNP:5217
664 664 a, t dbSNP:760229694
665 665 c, t dbSNP:80356625
666 666 a, g, t dbSNP:80356624
676 676 a, c dbSNP:577757932
680 680 c, t dbSNP:775204908
685 685 a, g dbSNP:772121211
700 700 c, t dbSNP:759487287
714 714 c, t dbSNP:774156815
719 719 g, t dbSNP:371633969
725 725 a, c, t dbSNP:781450902
726 726 a, g dbSNP:768909861
728 728 a, c dbSNP:747090537
732 732 c, t dbSNP:561086953
733 733 c, g dbSNP:780169484
742 742 c, t dbSNP:74162102
743 743 a, g dbSNP:587783672
746 746 a, g dbSNP:147937000
748 748 c, t dbSNP:746308356
749 749 a, g dbSNP:587783673
754 754 a, g dbSNP:779320079
764 764 c, t dbSNP:757593972
772 772 a, g dbSNP:754205539
784 784 c, g dbSNP:368520582
790 790 c, t dbSNP:72554078
793 793 c, t dbSNP:752411054
794 794 a, g dbSNP:751772105
797 797 g, t dbSNP:199848733
809 809 a, g dbSNP:375200088
817 817 c, g dbSNP:370638485
819 819 c, t dbSNP:193929352
823 823 c, g, t dbSNP:772950264
825 825 c, t dbSNP:104894237
826 826 a, g dbSNP:761931092
836 836 c, t dbSNP:747180509
837 837 a, g dbSNP:775698456
840 840 a, g dbSNP:104894248
844 844 c, t dbSNP:745958766
852 852 a, c dbSNP:779455025
862 862 a, g dbSNP:376027906
865 865 c, g dbSNP:5216
868 868 c, t dbSNP:778225010
869 869 a, g dbSNP:756552714
872 872 a, c, g dbSNP:1800467
877 877 -, t dbSNP:764143976
877 877 a, t dbSNP:754512091
881 881 a, g dbSNP:751068069
883 883 c, t dbSNP:202238153
884 884 a, g, t dbSNP:773218695
891 891 a, c dbSNP:113498300
892 892 c, t dbSNP:764950479
895 895 c, t dbSNP:761628495
907 907 c, t dbSNP:116392938
908 908 a, g dbSNP:267607196
913 913 c, t dbSNP:745931687
916 916 a, c, t dbSNP:1800854
917 917 a, g dbSNP:149667199
931 931 c, t dbSNP:573946686
932 932 a, g, t dbSNP:750414160
934 934 c, g dbSNP:201379919
945 945 c, t dbSNP:780957825
946 946 a, g dbSNP:115585638
950 950 a, c, g dbSNP:193929353
964 964 c, t dbSNP:751069491
965 965 c, t dbSNP:377091338
966 966 a, g, t dbSNP:74339576
967 967 c, t dbSNP:200855007
969 969 c, t dbSNP:761575495
976 976 c, g, t dbSNP:372471215
978 978 c, t dbSNP:759618669
982 982 c, t dbSNP:377040874
983 983 a, g dbSNP:770875360
991 991 a, c dbSNP:372180195
998 998 a, g dbSNP:72554079
1000 1000 c, t dbSNP:139445409
1004 1004 c, t dbSNP:748516747
1005 1005 a, g dbSNP:145935651
1016 1016 a, g dbSNP:369179692
1028 1028 a, g dbSNP:193929355
1030 1030 a, g dbSNP:746578913
1037 1037 a, c, t dbSNP:550315112
1038 1038 a, c, g dbSNP:778793458
1042 1042 c, t dbSNP:757254860
1052 1052 c, t dbSNP:587783675
1053 1053 a, g dbSNP:193929356
1054 1054 c, t dbSNP:753784994
1056 1056 c, g dbSNP:763728797
1061 1061 a, t dbSNP:193929357
1065 1065 a, g dbSNP:193929358
1072 1072 a, c, t dbSNP:538566992
1073 1073 a, g dbSNP:5215
1080 1080 g, t dbSNP:138125678
1081 1081 a, g, t dbSNP:770408379
1095 1095 g, t dbSNP:762355661
1098 1098 a, c, t dbSNP:114215135
1099 1099 a, g dbSNP:747426640
1103 1103 c, t dbSNP:146255794
1104 1104 a, g dbSNP:771797701
1108 1108 c, g dbSNP:745379486
1110 1110 c, t dbSNP:761453394
1115 1115 a, g dbSNP:778334034
1122 1122 a, g dbSNP:756762581
1124 1124 a, g dbSNP:749183151
1141 1141 a, g dbSNP:777788092
1148 1148 a, g dbSNP:755839409
1152 1152 c, t dbSNP:375859605
1153 1153 a, g dbSNP:5214
1157 1157 c, t dbSNP:758749160
1158 1158 a, g dbSNP:750689750
1159 1159 c, t dbSNP:143276279
1160 1160 a, g dbSNP:149141985
1163 1163 -, c dbSNP:35043381
1163 1163 c, t dbSNP:138168190
1169 1169 a, c, t dbSNP:371275937
1170 1170 a, g dbSNP:114613745
1175 1175 c, t dbSNP:771613078
1180 1180 c, t dbSNP:753294641
1181 1181 a, c, g dbSNP:770375846
1184 1184 c, t dbSNP:748841051
1187 1187 a, g dbSNP:777540229
1207 1207 -, cccaag dbSNP:775746898
1207 1207 a, g dbSNP:8175351
1214 1214 a, c, g dbSNP:141904039
1215 1215 a, t dbSNP:557050704
1216 1216 c, t dbSNP:184094021
1218 1218 c, g, t dbSNP:41282930
1223 1223 a, c, g dbSNP:753994346
1224 1224 a, g dbSNP:764508494
1250 1250 c, t dbSNP:560039845
1251 1251 a, g dbSNP:375713439
1256 1256 c, t dbSNP:767827389
1259 1259 a, c dbSNP:759913615
1263 1263 -, a dbSNP:765360093
1263 1263 c, t dbSNP:773965960
1264 1264 a, g dbSNP:770610826
1265 1265 c, t dbSNP:372394648
1266 1266 a, g dbSNP:370047076
1268 1268 a, g dbSNP:199834960
1271 1271 -, tacacac dbSNP:759640892
1273 1273 c, g dbSNP:748053505
1275 1275 c, g dbSNP:555307205
1276 1276 a, g dbSNP:768523190
1277 1277 c, t dbSNP:746850899
1278 1278 a, g dbSNP:775088753
1280 1280 a, c, g dbSNP:757623564
1284 1284 c, t dbSNP:753852754
1288 1288 a, g dbSNP:777853627
1299 1299 a, g, t dbSNP:5213
1302 1302 c, t dbSNP:557821086
1313 1313 a, g dbSNP:193076739
1329 1329 c, t dbSNP:5212
1345 1345 a, c dbSNP:139391954
1362 1362 a, g dbSNP:763277868
1398 1398 c, g dbSNP:77674298
1409 1409 a, c dbSNP:5211
1410 1410 a, c dbSNP:567290120
1449 1449 a, g dbSNP:115811959
1452 1452 c, t dbSNP:5210
1477 1477 a, g dbSNP:770194798
1501 1501 a, g dbSNP:185542065
1524 1524 c, t dbSNP:113019623
1525 1525 a, g dbSNP:5209
1556 1556 c, g dbSNP:533601283
1565 1565 c, t dbSNP:748617845
1572 1572 c, t dbSNP:118179872
1573 1573 a, g dbSNP:541725017
1574 1574 a, g dbSNP:372737066
1596 1596 c, t dbSNP:529498937
1597 1597 a, g dbSNP:561755715
1613 1613 c, t dbSNP:5208
1640 1640 a, g dbSNP:576026175
1671 1671 a, t dbSNP:148712397
1673 1673 -, g dbSNP:35294169
1678 1678 c, t dbSNP:2285676
1693 1693 c, t dbSNP:369186082
1724 1724 a, g dbSNP:79457490
1765 1765 c, t dbSNP:377292224
1766 1766 a, g dbSNP:115826080
1792 1792 g, t dbSNP:771668899
1795 1795 c, g dbSNP:534917931
1801 1801 c, t dbSNP:567523345
1802 1802 a, g dbSNP:555689354
1816 1816 a, g dbSNP:745646969
1826 1826 a, g dbSNP:185669328
1827 1827 a, g dbSNP:778704841
1923 1923 a, g dbSNP:147282653
1934 1934 a, g dbSNP:117976105
1938 1938 a, t dbSNP:5207
1953 1953 a, g dbSNP:561545376
1976 1976 a, g dbSNP:543277374
2003 2003 a, g dbSNP:193101892
2064 2064 c, t dbSNP:372655579
2085 2085 a, g dbSNP:5206
2099 2099 g, t dbSNP:547635594
2107 2107 a, g dbSNP:372136553
2137 2137 a, g dbSNP:529436579
2142 2142 a, g dbSNP:186637027
2154 2154 a, g dbSNP:562092401
2226 2226 c, t dbSNP:5205
2252 2252 c, t dbSNP:531631096
2270 2270 c, t dbSNP:564292096
2271 2271 a, g dbSNP:528111410
2272 2272 c, t dbSNP:770375661
2274 2274 g, t dbSNP:767140617
2278 2278 a, g dbSNP:763437250
2291 2291 c, t dbSNP:572399316
2360 2360 g, t dbSNP:553139186
2369 2369 c, g dbSNP:191697899
2375 2375 -, c dbSNP:35749958
2405 2405 a, g dbSNP:182349583
2415 2415 a, g dbSNP:573875884
2418 2418 a, g dbSNP:76774792
2419 2419 a, g dbSNP:74831871
2434 2434 a, g dbSNP:191682072
2465 2465 c, t dbSNP:765576308
2651 2651 c, t dbSNP:762247193
2666 2666 g, t dbSNP:537326228
2792 2792 c, g dbSNP:569535045
2813 2813 a, c dbSNP:569684578
2826 2826 c, t dbSNP:777153571
2840 2840 c, t dbSNP:768897061
2875 2875 g, t dbSNP:781637981
2890 2890 a, c, t dbSNP:563531727

Target ORF information:

RefSeq Version XM_006718226
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens potassium channel, inwardly rectifying subfamily J, member 11 (KCNJ11), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_006718226

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGGCCTGGT GGCTCATCGC CTTCGCCCAC GGTGACCTGG CCCCCAGCGA GGGCACTGCT 
GAGCCCTGTG TCACCAGCAT CCACTCCTTC TCGTCTGCCT TCCTTTTCTC CATTGAGGTC
CAAGTGACTA TTGGCTTTGG GGGGCGCATG GTGACTGAGG AGTGCCCACT GGCCATCCTG
ATCCTCATCG TGCAGAACAT CGTGGGGCTC ATGATCAACG CCATCATGCT TGGCTGCATC
TTCATGAAGA CTGCCCAAGC CCACCGCAGG GCTGAGACCC TCATCTTCAG CAAGCATGCG
GTGATCGCCC TGCGCCACGG CCGCCTCTGC TTCATGCTAC GTGTGGGTGA CCTCCGCAAG
AGCATGATCA TCAGCGCCAC CATCCACATG CAGGTGGTAC GCAAGACCAC CAGCCCCGAG
GGCGAGGTGG TGCCCCTCCA CCAGGTGGAC ATCCCCATGG AGAACGGCGT GGGTGGCAAC
AGCATCTTCC TGGTGGCCCC GCTGATCATC TACCATGTCA TTGATGCCAA CAGCCCACTC
TACGACCTGG CACCCAGCGA CCTGCACCAC CACCAGGACC TCGAGATCAT CGTCATCCTG
GAAGGCGTGG TGGAAACCAC GGGCATCACC ACCCAGGCCC GCACCTCCTA CCTGGCCGAT
GAGATCCTGT GGGGCCAGCG CTTTGTGCCC ATTGTAGCTG AGGAGGACGG ACGTTACTCT
GTGGACTACT CCAAGTTTGG CAACACCGTC AAAGTGCCCA CACCACTCTG CACGGCCCGC
CAGCTTGATG AGGACCACAG CCTACTGGAA GCTCTGACCC TCGCCTCAGC CCGCGGGCCC
CTGCGCAAGC GCAGCGTGCC CATGGCCAAG GCCAAGCCCA AGTTCAGCAT CTCTCCAGAT
TCCCTGTCCT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu20898
Accession Version NM_001166290.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 912bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product ATP-sensitive inward rectifier potassium channel 11 isoform 2
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK301550.1, AC124798.5 and AI377272.1. Summary: Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and is found associated with the sulfonylurea receptor SUR. Mutations in this gene are a cause of familial persistent hyperinsulinemic hypoglycemia of infancy (PHHI), an autosomal recessive disorder characterized by unregulated insulin secretion. Defects in this gene may also contribute to autosomal dominant non-insulin-dependent diabetes mellitus type II (NIDDM), transient neonatal diabetes mellitus type 3 (TNDM3), and permanent neonatal diabetes mellitus (PNDM). Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Oct 2009]. Transcript Variant: This variant (2) uses a different segment for its 5' UTR and lacks 5' coding region sequence, compared to variant 1. Variant 2 uses a downstream start codon, which results in a protein (isoform 2) with a shorter N-terminus when it is compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK301550.1, BC040617.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2154361, SAMEA962332 [ECO:0000348] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGGCCTGGT GGCTCATCGC CTTCGCCCAC GGTGACCTGG CCCCCAGCGA GGGCACTGCT 
GAGCCCTGTG TCACCAGCAT CCACTCCTTC TCGTCTGCCT TCCTTTTCTC CATTGAGGTC
CAAGTGACTA TTGGCTTTGG GGGGCGCATG GTGACTGAGG AGTGCCCACT GGCCATCCTG
ATCCTCATCG TGCAGAACAT CGTGGGGCTC ATGATCAACG CCATCATGCT TGGCTGCATC
TTCATGAAGA CTGCCCAAGC CCACCGCAGG GCTGAGACCC TCATCTTCAG CAAGCATGCG
GTGATCGCCC TGCGCCACGG CCGCCTCTGC TTCATGCTAC GTGTGGGTGA CCTCCGCAAG
AGCATGATCA TCAGCGCCAC CATCCACATG CAGGTGGTAC GCAAGACCAC CAGCCCCGAG
GGCGAGGTGG TGCCCCTCCA CCAGGTGGAC ATCCCCATGG AGAACGGCGT GGGTGGCAAC
AGCATCTTCC TGGTGGCCCC GCTGATCATC TACCATGTCA TTGATGCCAA CAGCCCACTC
TACGACCTGG CACCCAGCGA CCTGCACCAC CACCAGGACC TCGAGATCAT CGTCATCCTG
GAAGGCGTGG TGGAAACCAC GGGCATCACC ACCCAGGCCC GCACCTCCTA CCTGGCCGAT
GAGATCCTGT GGGGCCAGCG CTTTGTGCCC ATTGTAGCTG AGGAGGACGG ACGTTACTCT
GTGGACTACT CCAAGTTTGG CAACACCGTC AAAGTGCCCA CACCACTCTG CACGGCCCGC
CAGCTTGATG AGGACCACAG CCTACTGGAA GCTCTGACCC TCGCCTCAGC CCGCGGGCCC
CTGCGCAAGC GCAGCGTGCC CATGGCCAAG GCCAAGCCCA AGTTCAGCAT CTCTCCAGAT
TCCCTGTCCT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqNP_001159762.1
CDS175..1086
Misc Feature(1)175..984(+)
Exon (1)1..158
Gene:KCNJ11
Gene Synonym:
Exon (2)159..2757
Gene:KCNJ11
Gene Synonym:
Translation
Position Chain Variation Link
3 3 a, g dbSNP:540299909
10 10 c, t dbSNP:573373761
99 99 a, g dbSNP:555117455
163 163 c, t dbSNP:758281673
171 171 c, t dbSNP:754048558
172 172 a, g dbSNP:764444072
175 175 a, t dbSNP:756124560
189 189 c, t dbSNP:752859952
192 192 c, t dbSNP:142577961
193 193 a, g dbSNP:138065534
198 198 c, t dbSNP:774849547
199 199 a, g dbSNP:766658650
204 204 a, c, t dbSNP:371886780
206 206 a, g dbSNP:769538059
211 211 -, c dbSNP:767164487
216 216 c, t dbSNP:747582437
219 219 c, t dbSNP:776275457
221 221 g, t dbSNP:200932525
222 222 a, c, t dbSNP:376773562
223 223 a, g dbSNP:145429555
238 238 a, c dbSNP:758228551
247 247 a, g dbSNP:745705365
250 250 a, g dbSNP:778108404
257 257 a, g dbSNP:374334444
258 258 c, t dbSNP:769962094
263 263 -, tct dbSNP:757062550
266 266 c, t dbSNP:756424776
267 267 a, g dbSNP:140636367
268 268 g, t dbSNP:781271888
317 317 a, g dbSNP:755013629
318 318 -, g dbSNP:557160758
318 318 g, t dbSNP:752018515
319 319 c, t dbSNP:766891274
324 324 a, g dbSNP:371977895
353 353 c, t dbSNP:28936678
360 360 c, t dbSNP:764796514
363 363 c, t dbSNP:761588360
364 364 a, g dbSNP:529884745
375 375 c, t dbSNP:145757832
376 376 a, g dbSNP:587783668
381 381 a, g dbSNP:748158864
384 384 c, t dbSNP:116045724
393 393 c, t dbSNP:568688504
406 406 a, g dbSNP:775520445
410 410 a, g, t dbSNP:80356618
411 411 c, g dbSNP:587783669
412 412 a, c dbSNP:80356620
422 422 a, g dbSNP:80356621
423 423 c, g dbSNP:80356622
434 434 c, g dbSNP:587783670
439 439 c, t dbSNP:201264306
445 445 a, g dbSNP:745652318
449 449 a, c dbSNP:587783671
453 453 c, g dbSNP:778825557
457 457 a, g dbSNP:193929348
480 480 a, c, t dbSNP:114899765
481 481 a, c, g dbSNP:77131926
483 483 a, c, t dbSNP:5218
487 487 c, t dbSNP:780511484
488 488 a, g, t dbSNP:750778014
491 491 a, g dbSNP:373657240
492 492 c, t dbSNP:762089425
496 496 c, t dbSNP:753491511
497 497 a, g dbSNP:5217
513 513 a, t dbSNP:760229694
514 514 c, t dbSNP:80356625
515 515 a, g, t dbSNP:80356624
525 525 a, c dbSNP:577757932
529 529 c, t dbSNP:775204908
534 534 a, g dbSNP:772121211
549 549 c, t dbSNP:759487287
563 563 c, t dbSNP:774156815
568 568 g, t dbSNP:371633969
574 574 a, c, t dbSNP:781450902
575 575 a, g dbSNP:768909861
577 577 a, c dbSNP:747090537
581 581 c, t dbSNP:561086953
582 582 c, g dbSNP:780169484
591 591 c, t dbSNP:74162102
592 592 a, g dbSNP:587783672
595 595 a, g dbSNP:147937000
597 597 c, t dbSNP:746308356
598 598 a, g dbSNP:587783673
603 603 a, g dbSNP:779320079
613 613 c, t dbSNP:757593972
621 621 a, g dbSNP:754205539
633 633 c, g dbSNP:368520582
639 639 c, t dbSNP:72554078
642 642 c, t dbSNP:752411054
643 643 a, g dbSNP:751772105
646 646 g, t dbSNP:199848733
658 658 a, g dbSNP:375200088
666 666 c, g dbSNP:370638485
668 668 c, t dbSNP:193929352
672 672 c, g, t dbSNP:772950264
674 674 c, t dbSNP:104894237
675 675 a, g dbSNP:761931092
685 685 c, t dbSNP:747180509
686 686 a, g dbSNP:775698456
689 689 a, g dbSNP:104894248
693 693 c, t dbSNP:745958766
701 701 a, c dbSNP:779455025
711 711 a, g dbSNP:376027906
714 714 c, g dbSNP:5216
717 717 c, t dbSNP:778225010
718 718 a, g dbSNP:756552714
721 721 a, c, g dbSNP:1800467
726 726 -, t dbSNP:764143976
726 726 a, t dbSNP:754512091
730 730 a, g dbSNP:751068069
732 732 c, t dbSNP:202238153
733 733 a, g, t dbSNP:773218695
740 740 a, c dbSNP:113498300
741 741 c, t dbSNP:764950479
744 744 c, t dbSNP:761628495
756 756 c, t dbSNP:116392938
757 757 a, g dbSNP:267607196
762 762 c, t dbSNP:745931687
765 765 a, c, t dbSNP:1800854
766 766 a, g dbSNP:149667199
780 780 c, t dbSNP:573946686
781 781 a, g, t dbSNP:750414160
783 783 c, g dbSNP:201379919
794 794 c, t dbSNP:780957825
795 795 a, g dbSNP:115585638
799 799 a, c, g dbSNP:193929353
813 813 c, t dbSNP:751069491
814 814 c, t dbSNP:377091338
815 815 a, g, t dbSNP:74339576
816 816 c, t dbSNP:200855007
818 818 c, t dbSNP:761575495
825 825 c, g, t dbSNP:372471215
827 827 c, t dbSNP:759618669
831 831 c, t dbSNP:377040874
832 832 a, g dbSNP:770875360
840 840 a, c dbSNP:372180195
847 847 a, g dbSNP:72554079
849 849 c, t dbSNP:139445409
853 853 c, t dbSNP:748516747
854 854 a, g dbSNP:145935651
865 865 a, g dbSNP:369179692
877 877 a, g dbSNP:193929355
879 879 a, g dbSNP:746578913
886 886 a, c, t dbSNP:550315112
887 887 a, c, g dbSNP:778793458
891 891 c, t dbSNP:757254860
901 901 c, t dbSNP:587783675
902 902 a, g dbSNP:193929356
903 903 c, t dbSNP:753784994
905 905 c, g dbSNP:763728797
910 910 a, t dbSNP:193929357
914 914 a, g dbSNP:193929358
921 921 a, c, t dbSNP:538566992
922 922 a, g dbSNP:5215
929 929 g, t dbSNP:138125678
930 930 a, g, t dbSNP:770408379
944 944 g, t dbSNP:762355661
947 947 a, c, t dbSNP:114215135
948 948 a, g dbSNP:747426640
952 952 c, t dbSNP:146255794
953 953 a, g dbSNP:771797701
957 957 c, g dbSNP:745379486
959 959 c, t dbSNP:761453394
964 964 a, g dbSNP:778334034
971 971 a, g dbSNP:756762581
973 973 a, g dbSNP:749183151
990 990 a, g dbSNP:777788092
997 997 a, g dbSNP:755839409
1001 1001 c, t dbSNP:375859605
1002 1002 a, g dbSNP:5214
1006 1006 c, t dbSNP:758749160
1007 1007 a, g dbSNP:750689750
1008 1008 c, t dbSNP:143276279
1009 1009 a, g dbSNP:149141985
1012 1012 -, c dbSNP:35043381
1012 1012 c, t dbSNP:138168190
1018 1018 a, c, t dbSNP:371275937
1019 1019 a, g dbSNP:114613745
1024 1024 c, t dbSNP:771613078
1029 1029 c, t dbSNP:753294641
1030 1030 a, c, g dbSNP:770375846
1033 1033 c, t dbSNP:748841051
1036 1036 a, g dbSNP:777540229
1056 1056 -, cccaag dbSNP:775746898
1056 1056 a, g dbSNP:8175351
1063 1063 a, c, g dbSNP:141904039
1064 1064 a, t dbSNP:557050704
1065 1065 c, t dbSNP:184094021
1067 1067 c, g, t dbSNP:41282930
1072 1072 a, c, g dbSNP:753994346
1073 1073 a, g dbSNP:764508494
1099 1099 c, t dbSNP:560039845
1100 1100 a, g dbSNP:375713439
1105 1105 c, t dbSNP:767827389
1108 1108 a, c dbSNP:759913615
1112 1112 -, a dbSNP:765360093
1112 1112 c, t dbSNP:773965960
1113 1113 a, g dbSNP:770610826
1114 1114 c, t dbSNP:372394648
1115 1115 a, g dbSNP:370047076
1117 1117 a, g dbSNP:199834960
1120 1120 -, tacacac dbSNP:759640892
1122 1122 c, g dbSNP:748053505
1124 1124 c, g dbSNP:555307205
1125 1125 a, g dbSNP:768523190
1126 1126 c, t dbSNP:746850899
1127 1127 a, g dbSNP:775088753
1129 1129 a, c, g dbSNP:757623564
1133 1133 c, t dbSNP:753852754
1137 1137 a, g dbSNP:777853627
1148 1148 a, g, t dbSNP:5213
1151 1151 c, t dbSNP:557821086
1162 1162 a, g dbSNP:193076739
1178 1178 c, t dbSNP:5212
1194 1194 a, c dbSNP:139391954
1211 1211 a, g dbSNP:763277868
1247 1247 c, g dbSNP:77674298
1258 1258 a, c dbSNP:5211
1259 1259 a, c dbSNP:567290120
1298 1298 a, g dbSNP:115811959
1301 1301 c, t dbSNP:5210
1326 1326 a, g dbSNP:770194798
1350 1350 a, g dbSNP:185542065
1373 1373 c, t dbSNP:113019623
1374 1374 a, g dbSNP:5209
1405 1405 c, g dbSNP:533601283
1414 1414 c, t dbSNP:748617845
1421 1421 c, t dbSNP:118179872
1422 1422 a, g dbSNP:541725017
1423 1423 a, g dbSNP:372737066
1445 1445 c, t dbSNP:529498937
1446 1446 a, g dbSNP:561755715
1462 1462 c, t dbSNP:5208
1489 1489 a, g dbSNP:576026175
1520 1520 a, t dbSNP:148712397
1522 1522 -, g dbSNP:35294169
1527 1527 c, t dbSNP:2285676
1542 1542 c, t dbSNP:369186082
1573 1573 a, g dbSNP:79457490
1614 1614 c, t dbSNP:377292224
1615 1615 a, g dbSNP:115826080
1641 1641 g, t dbSNP:771668899
1644 1644 c, g dbSNP:534917931
1650 1650 c, t dbSNP:567523345
1651 1651 a, g dbSNP:555689354
1665 1665 a, g dbSNP:745646969
1675 1675 a, g dbSNP:185669328
1676 1676 a, g dbSNP:778704841
1772 1772 a, g dbSNP:147282653
1783 1783 a, g dbSNP:117976105
1787 1787 a, t dbSNP:5207
1802 1802 a, g dbSNP:561545376
1825 1825 a, g dbSNP:543277374
1852 1852 a, g dbSNP:193101892
1913 1913 c, t dbSNP:372655579
1934 1934 a, g dbSNP:5206
1948 1948 g, t dbSNP:547635594
1956 1956 a, g dbSNP:372136553
1986 1986 a, g dbSNP:529436579
1991 1991 a, g dbSNP:186637027
2003 2003 a, g dbSNP:562092401
2075 2075 c, t dbSNP:5205
2101 2101 c, t dbSNP:531631096
2119 2119 c, t dbSNP:564292096
2120 2120 a, g dbSNP:528111410
2121 2121 c, t dbSNP:770375661
2123 2123 g, t dbSNP:767140617
2127 2127 a, g dbSNP:763437250
2140 2140 c, t dbSNP:572399316
2209 2209 g, t dbSNP:553139186
2218 2218 c, g dbSNP:191697899
2224 2224 -, c dbSNP:35749958
2254 2254 a, g dbSNP:182349583
2264 2264 a, g dbSNP:573875884
2267 2267 a, g dbSNP:76774792
2268 2268 a, g dbSNP:74831871
2283 2283 a, g dbSNP:191682072
2314 2314 c, t dbSNP:765576308
2500 2500 c, t dbSNP:762247193
2515 2515 g, t dbSNP:537326228
2641 2641 c, g dbSNP:569535045
2662 2662 a, c dbSNP:569684578
2675 2675 c, t dbSNP:777153571
2689 2689 c, t dbSNP:768897061
2724 2724 g, t dbSNP:781637981
2739 2739 a, c, t dbSNP:563531727

Target ORF information:

RefSeq Version NM_001166290
Organism Homo sapiens (human)
Definition Homo sapiens potassium channel, inwardly rectifying subfamily J, member 11 (KCNJ11), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001166290

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGGCCTGGT GGCTCATCGC CTTCGCCCAC GGTGACCTGG CCCCCAGCGA GGGCACTGCT 
GAGCCCTGTG TCACCAGCAT CCACTCCTTC TCGTCTGCCT TCCTTTTCTC CATTGAGGTC
CAAGTGACTA TTGGCTTTGG GGGGCGCATG GTGACTGAGG AGTGCCCACT GGCCATCCTG
ATCCTCATCG TGCAGAACAT CGTGGGGCTC ATGATCAACG CCATCATGCT TGGCTGCATC
TTCATGAAGA CTGCCCAAGC CCACCGCAGG GCTGAGACCC TCATCTTCAG CAAGCATGCG
GTGATCGCCC TGCGCCACGG CCGCCTCTGC TTCATGCTAC GTGTGGGTGA CCTCCGCAAG
AGCATGATCA TCAGCGCCAC CATCCACATG CAGGTGGTAC GCAAGACCAC CAGCCCCGAG
GGCGAGGTGG TGCCCCTCCA CCAGGTGGAC ATCCCCATGG AGAACGGCGT GGGTGGCAAC
AGCATCTTCC TGGTGGCCCC GCTGATCATC TACCATGTCA TTGATGCCAA CAGCCCACTC
TACGACCTGG CACCCAGCGA CCTGCACCAC CACCAGGACC TCGAGATCAT CGTCATCCTG
GAAGGCGTGG TGGAAACCAC GGGCATCACC ACCCAGGCCC GCACCTCCTA CCTGGCCGAT
GAGATCCTGT GGGGCCAGCG CTTTGTGCCC ATTGTAGCTG AGGAGGACGG ACGTTACTCT
GTGGACTACT CCAAGTTTGG CAACACCGTC AAAGTGCCCA CACCACTCTG CACGGCCCGC
CAGCTTGATG AGGACCACAG CCTACTGGAA GCTCTGACCC TCGCCTCAGC CCGCGGGCCC
CTGCGCAAGC GCAGCGTGCC CATGGCCAAG GCCAAGCCCA AGTTCAGCAT CTCTCCAGAT
TCCCTGTCCT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

 
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