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KCNJ11 cDNA ORF clone, Homo sapiens (human)

Gene Symbol KCNJ11
Entrez Gene ID 3767
Full Name potassium channel, inwardly rectifying subfamily J, member 11
Synonyms BIR, HHF2, IKATP, KIR6.2, MODY13, PHHI, TNDM3
General protein information
Preferred Names
ATP-sensitive inward rectifier potassium channel 11
Names
ATP-sensitive inward rectifier potassium channel 11
beta-cell inward rectifier subunit
inward rectifier K(+) channel Kir6.2
inwardly rectifying potassium channel KIR6.2
potassium channel inwardly rectifing subfamily J member 11
potassium channel, inwardly rectifying subfamily J member 11
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

11

11p15.1

Summary Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and is found associated with the sulfonylurea receptor SUR. Mutations in this gene are a cause of familial persistent hyperinsulinemic hypoglycemia of infancy (PHHI), an autosomal recessive disorder characterized by unregulated insulin secretion. Defects in this gene may also contribute to autosomal dominant non-insulin-dependent diabetes mellitus type II (NIDDM), transient neonatal diabetes mellitus type 3 (TNDM3), and permanent neonatal diabetes mellitus (PNDM). Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Oct 2009]. lac of sum
Disorder MIM:

600937

Disorder Html: Hyperinsulinemic hypoglycemia, familial, 2, 601820 (3);

mRNA and Protein(s)

mRNA Protein Name
NM_000525 NP_000516 ATP-sensitive inward rectifier potassium channel 11 isoform 1
XM_006718226 XP_006718289 ATP-sensitive inward rectifier potassium channel 11 isoform X1
NM_001166290 NP_001159762 ATP-sensitive inward rectifier potassium channel 11 isoform 2



Homo sapiens (human) KCNJ11 NP_000516.3
Pan troglodytes (chimpanzee) KCNJ11 XP_521849.2
Macaca mulatta (Rhesus monkey) KCNJ11 XP_001089155.1
Canis lupus familiaris (dog) KCNJ11 XP_542519.2
Bos taurus (cattle) KCNJ11 NP_001075067.1
Mus musculus (house mouse) Kcnj11 NP_034732.1
Rattus norvegicus (Norway rat) Kcnj11 NP_112648.2
Gallus gallus (chicken) KCNJ11 XP_426402.4
Danio rerio (zebrafish) kcnj11 NP_001034916.1
Xenopus (Silurana) tropicalis (western clawed frog) LOC100492679 XP_004916335.1


GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following KCNJ11 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the KCNJ11 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu19078 NM_000525 Homo sapiens potassium channel, inwardly rectifying subfamily J, member 11 (KCNJ11), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $223.30
$319.00
OHu20898 XM_006718226 PREDICTED: Homo sapiens potassium channel, inwardly rectifying subfamily J, member 11 (KCNJ11), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $139.30
$199.00
OHu20898 NM_001166290 Homo sapiens potassium channel, inwardly rectifying subfamily J, member 11 (KCNJ11), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $139.30
$199.00
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu19078
Clone ID Related Accession (Same CDS sequence) NM_000525
Accession Version NM_000525.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1173bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 18-JAN-2015
Organism Homo sapiens (human)
Product ATP-sensitive inward rectifier potassium channel 11 isoform 1
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC124798.5 and AI377272.1. This sequence is a reference standard in the RefSeqGene project. On Apr 7, 2005 this sequence version replaced gi:25777631. Transcript Variant: This variant (1) encodes the longer protein (isoform 1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. COMPLETENESS: full length.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
ATGCTGTCCC GCAAGGGCAT CATCCCCGAG GAATACGTGC TGACACGCCT GGCAGAGGAC 
CCTGCCAAGC CCAGGTACCG TGCCCGCCAG CGGAGGGCCC GCTTTGTGTC CAAGAAAGGC
AACTGCAACG TGGCCCACAA GAACATCCGG GAGCAGGGCC GCTTCCTGCA GGACGTGTTC
ACCACGCTGG TGGACCTCAA GTGGCCACAC ACATTGCTCA TCTTCACCAT GTCCTTCCTG
TGCAGCTGGC TGCTCTTCGC CATGGCCTGG TGGCTCATCG CCTTCGCCCA CGGTGACCTG
GCCCCCAGCG AGGGCACTGC TGAGCCCTGT GTCACCAGCA TCCACTCCTT CTCGTCTGCC
TTCCTTTTCT CCATTGAGGT CCAAGTGACT ATTGGCTTTG GGGGGCGCAT GGTGACTGAG
GAGTGCCCAC TGGCCATCCT GATCCTCATC GTGCAGAACA TCGTGGGGCT CATGATCAAC
GCCATCATGC TTGGCTGCAT CTTCATGAAG ACTGCCCAAG CCCACCGCAG GGCTGAGACC
CTCATCTTCA GCAAGCATGC GGTGATCGCC CTGCGCCACG GCCGCCTCTG CTTCATGCTA
CGTGTGGGTG ACCTCCGCAA GAGCATGATC ATCAGCGCCA CCATCCACAT GCAGGTGGTA
CGCAAGACCA CCAGCCCCGA GGGCGAGGTG GTGCCCCTCC ACCAGGTGGA CATCCCCATG
GAGAACGGCG TGGGTGGCAA CAGCATCTTC CTGGTGGCCC CGCTGATCAT CTACCATGTC
ATTGATGCCA ACAGCCCACT CTACGACCTG GCACCCAGCG ACCTGCACCA CCACCAGGAC
CTCGAGATCA TCGTCATCCT GGAAGGCGTG GTGGAAACCA CGGGCATCAC CACCCAGGCC
CGCACCTCCT ACCTGGCCGA TGAGATCCTG TGGGGCCAGC GCTTTGTGCC CATTGTAGCT
GAGGAGGACG GACGTTACTC TGTGGACTAC TCCAAGTTTG GCAACACCGT CAAAGTGCCC
ACACCACTCT GCACGGCCCG CCAGCTTGAT GAGGACCACA GCCTACTGGA AGCTCTGACC
CTCGCCTCAG CCCGCGGGCC CCTGCGCAAG CGCAGCGTGC CCATGGCCAA GGCCAAGCCC
AAGTTCAGCA TCTCTCCAGA TTCCCTGTCC TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_000516.3
CDS569..1741
Misc Feature(1)348..348(+)
Misc Feature(2)500..502(+)
Misc Feature(3)674..1639(+)
Misc Feature(4)773..847(+)
Misc Feature(5)956..973(+)
Misc Feature(6)1001..1066(+)
Misc Feature(7)1046..1048(+)
Misc Feature(8)1589..1591(+)
Misc Feature(9)1721..1723(+)
Exon (1)1..3412
Gene:KCNJ11
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_000525
Organism Homo sapiens (human)
Definition Homo sapiens potassium channel, inwardly rectifying subfamily J, member 11 (KCNJ11), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_000525

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
ATGCTGTCCC GCAAGGGCAT CATCCCCGAG GAATACGTGC TGACACGCCT GGCAGAGGAC 
CCTGCCAAGC CCAGGTACCG TGCCCGCCAG CGGAGGGCCC GCTTTGTGTC CAAGAAAGGC
AACTGCAACG TGGCCCACAA GAACATCCGG GAGCAGGGCC GCTTCCTGCA GGACGTGTTC
ACCACGCTGG TGGACCTCAA GTGGCCACAC ACATTGCTCA TCTTCACCAT GTCCTTCCTG
TGCAGCTGGC TGCTCTTCGC CATGGCCTGG TGGCTCATCG CCTTCGCCCA CGGTGACCTG
GCCCCCAGCG AGGGCACTGC TGAGCCCTGT GTCACCAGCA TCCACTCCTT CTCGTCTGCC
TTCCTTTTCT CCATTGAGGT CCAAGTGACT ATTGGCTTTG GGGGGCGCAT GGTGACTGAG
GAGTGCCCAC TGGCCATCCT GATCCTCATC GTGCAGAACA TCGTGGGGCT CATGATCAAC
GCCATCATGC TTGGCTGCAT CTTCATGAAG ACTGCCCAAG CCCACCGCAG GGCTGAGACC
CTCATCTTCA GCAAGCATGC GGTGATCGCC CTGCGCCACG GCCGCCTCTG CTTCATGCTA
CGTGTGGGTG ACCTCCGCAA GAGCATGATC ATCAGCGCCA CCATCCACAT GCAGGTGGTA
CGCAAGACCA CCAGCCCCGA GGGCGAGGTG GTGCCCCTCC ACCAGGTGGA CATCCCCATG
GAGAACGGCG TGGGTGGCAA CAGCATCTTC CTGGTGGCCC CGCTGATCAT CTACCATGTC
ATTGATGCCA ACAGCCCACT CTACGACCTG GCACCCAGCG ACCTGCACCA CCACCAGGAC
CTCGAGATCA TCGTCATCCT GGAAGGCGTG GTGGAAACCA CGGGCATCAC CACCCAGGCC
CGCACCTCCT ACCTGGCCGA TGAGATCCTG TGGGGCCAGC GCTTTGTGCC CATTGTAGCT
GAGGAGGACG GACGTTACTC TGTGGACTAC TCCAAGTTTG GCAACACCGT CAAAGTGCCC
ACACCACTCT GCACGGCCCG CCAGCTTGAT GAGGACCACA GCCTACTGGA AGCTCTGACC
CTCGCCTCAG CCCGCGGGCC CCTGCGCAAG CGCAGCGTGC CCATGGCCAA GGCCAAGCCC
AAGTTCAGCA TCTCTCCAGA TTCCCTGTCC TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu20898
Clone ID Related Accession (Same CDS sequence) NM_001166290 , XM_006718226
Accession Version XM_006718226.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 912bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product ATP-sensitive inward rectifier potassium channel 11 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_009237.19) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced gi:578820521. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGGCCTGGT GGCTCATCGC CTTCGCCCAC GGTGACCTGG CCCCCAGCGA GGGCACTGCT 
GAGCCCTGTG TCACCAGCAT CCACTCCTTC TCGTCTGCCT TCCTTTTCTC CATTGAGGTC
CAAGTGACTA TTGGCTTTGG GGGGCGCATG GTGACTGAGG AGTGCCCACT GGCCATCCTG
ATCCTCATCG TGCAGAACAT CGTGGGGCTC ATGATCAACG CCATCATGCT TGGCTGCATC
TTCATGAAGA CTGCCCAAGC CCACCGCAGG GCTGAGACCC TCATCTTCAG CAAGCATGCG
GTGATCGCCC TGCGCCACGG CCGCCTCTGC TTCATGCTAC GTGTGGGTGA CCTCCGCAAG
AGCATGATCA TCAGCGCCAC CATCCACATG CAGGTGGTAC GCAAGACCAC CAGCCCCGAG
GGCGAGGTGG TGCCCCTCCA CCAGGTGGAC ATCCCCATGG AGAACGGCGT GGGTGGCAAC
AGCATCTTCC TGGTGGCCCC GCTGATCATC TACCATGTCA TTGATGCCAA CAGCCCACTC
TACGACCTGG CACCCAGCGA CCTGCACCAC CACCAGGACC TCGAGATCAT CGTCATCCTG
GAAGGCGTGG TGGAAACCAC GGGCATCACC ACCCAGGCCC GCACCTCCTA CCTGGCCGAT
GAGATCCTGT GGGGCCAGCG CTTTGTGCCC ATTGTAGCTG AGGAGGACGG ACGTTACTCT
GTGGACTACT CCAAGTTTGG CAACACCGTC AAAGTGCCCA CACCACTCTG CACGGCCCGC
CAGCTTGATG AGGACCACAG CCTACTGGAA GCTCTGACCC TCGCCTCAGC CCGCGGGCCC
CTGCGCAAGC GCAGCGTGCC CATGGCCAAG GCCAAGCCCA AGTTCAGCAT CTCTCCAGAT
TCCCTGTCCT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006718289.1
CDS326..1237
Misc Feature(1)326..1135(+)
Translation

Target ORF information:

RefSeq Version XM_006718226
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens potassium channel, inwardly rectifying subfamily J, member 11 (KCNJ11), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_006718226

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGGCCTGGT GGCTCATCGC CTTCGCCCAC GGTGACCTGG CCCCCAGCGA GGGCACTGCT 
GAGCCCTGTG TCACCAGCAT CCACTCCTTC TCGTCTGCCT TCCTTTTCTC CATTGAGGTC
CAAGTGACTA TTGGCTTTGG GGGGCGCATG GTGACTGAGG AGTGCCCACT GGCCATCCTG
ATCCTCATCG TGCAGAACAT CGTGGGGCTC ATGATCAACG CCATCATGCT TGGCTGCATC
TTCATGAAGA CTGCCCAAGC CCACCGCAGG GCTGAGACCC TCATCTTCAG CAAGCATGCG
GTGATCGCCC TGCGCCACGG CCGCCTCTGC TTCATGCTAC GTGTGGGTGA CCTCCGCAAG
AGCATGATCA TCAGCGCCAC CATCCACATG CAGGTGGTAC GCAAGACCAC CAGCCCCGAG
GGCGAGGTGG TGCCCCTCCA CCAGGTGGAC ATCCCCATGG AGAACGGCGT GGGTGGCAAC
AGCATCTTCC TGGTGGCCCC GCTGATCATC TACCATGTCA TTGATGCCAA CAGCCCACTC
TACGACCTGG CACCCAGCGA CCTGCACCAC CACCAGGACC TCGAGATCAT CGTCATCCTG
GAAGGCGTGG TGGAAACCAC GGGCATCACC ACCCAGGCCC GCACCTCCTA CCTGGCCGAT
GAGATCCTGT GGGGCCAGCG CTTTGTGCCC ATTGTAGCTG AGGAGGACGG ACGTTACTCT
GTGGACTACT CCAAGTTTGG CAACACCGTC AAAGTGCCCA CACCACTCTG CACGGCCCGC
CAGCTTGATG AGGACCACAG CCTACTGGAA GCTCTGACCC TCGCCTCAGC CCGCGGGCCC
CTGCGCAAGC GCAGCGTGCC CATGGCCAAG GCCAAGCCCA AGTTCAGCAT CTCTCCAGAT
TCCCTGTCCT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu20898
Clone ID Related Accession (Same CDS sequence) NM_001166290 , XM_006718226
Accession Version NM_001166290.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 912bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product ATP-sensitive inward rectifier potassium channel 11 isoform 2
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK301550.1, AC124798.5 and AI377272.1. Transcript Variant: This variant (2) uses a different segment for its 5' UTR and lacks 5' coding region sequence, compared to variant 1. Variant 2 uses a downstream start codon, which results in a protein (isoform 2) with a shorter N-terminus when it is compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK301550.1, BC040617.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2154361, SAMEA962332 [ECO:0000348] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGGCCTGGT GGCTCATCGC CTTCGCCCAC GGTGACCTGG CCCCCAGCGA GGGCACTGCT 
GAGCCCTGTG TCACCAGCAT CCACTCCTTC TCGTCTGCCT TCCTTTTCTC CATTGAGGTC
CAAGTGACTA TTGGCTTTGG GGGGCGCATG GTGACTGAGG AGTGCCCACT GGCCATCCTG
ATCCTCATCG TGCAGAACAT CGTGGGGCTC ATGATCAACG CCATCATGCT TGGCTGCATC
TTCATGAAGA CTGCCCAAGC CCACCGCAGG GCTGAGACCC TCATCTTCAG CAAGCATGCG
GTGATCGCCC TGCGCCACGG CCGCCTCTGC TTCATGCTAC GTGTGGGTGA CCTCCGCAAG
AGCATGATCA TCAGCGCCAC CATCCACATG CAGGTGGTAC GCAAGACCAC CAGCCCCGAG
GGCGAGGTGG TGCCCCTCCA CCAGGTGGAC ATCCCCATGG AGAACGGCGT GGGTGGCAAC
AGCATCTTCC TGGTGGCCCC GCTGATCATC TACCATGTCA TTGATGCCAA CAGCCCACTC
TACGACCTGG CACCCAGCGA CCTGCACCAC CACCAGGACC TCGAGATCAT CGTCATCCTG
GAAGGCGTGG TGGAAACCAC GGGCATCACC ACCCAGGCCC GCACCTCCTA CCTGGCCGAT
GAGATCCTGT GGGGCCAGCG CTTTGTGCCC ATTGTAGCTG AGGAGGACGG ACGTTACTCT
GTGGACTACT CCAAGTTTGG CAACACCGTC AAAGTGCCCA CACCACTCTG CACGGCCCGC
CAGCTTGATG AGGACCACAG CCTACTGGAA GCTCTGACCC TCGCCTCAGC CCGCGGGCCC
CTGCGCAAGC GCAGCGTGCC CATGGCCAAG GCCAAGCCCA AGTTCAGCAT CTCTCCAGAT
TCCCTGTCCT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001159762.1
CDS175..1086
Misc Feature(1)175..984(+)
Exon (1)1..158
Gene:KCNJ11
Gene Synonym:
Exon (2)159..2757
Gene:KCNJ11
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001166290
Organism Homo sapiens (human)
Definition Homo sapiens potassium channel, inwardly rectifying subfamily J, member 11 (KCNJ11), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001166290

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGGCCTGGT GGCTCATCGC CTTCGCCCAC GGTGACCTGG CCCCCAGCGA GGGCACTGCT 
GAGCCCTGTG TCACCAGCAT CCACTCCTTC TCGTCTGCCT TCCTTTTCTC CATTGAGGTC
CAAGTGACTA TTGGCTTTGG GGGGCGCATG GTGACTGAGG AGTGCCCACT GGCCATCCTG
ATCCTCATCG TGCAGAACAT CGTGGGGCTC ATGATCAACG CCATCATGCT TGGCTGCATC
TTCATGAAGA CTGCCCAAGC CCACCGCAGG GCTGAGACCC TCATCTTCAG CAAGCATGCG
GTGATCGCCC TGCGCCACGG CCGCCTCTGC TTCATGCTAC GTGTGGGTGA CCTCCGCAAG
AGCATGATCA TCAGCGCCAC CATCCACATG CAGGTGGTAC GCAAGACCAC CAGCCCCGAG
GGCGAGGTGG TGCCCCTCCA CCAGGTGGAC ATCCCCATGG AGAACGGCGT GGGTGGCAAC
AGCATCTTCC TGGTGGCCCC GCTGATCATC TACCATGTCA TTGATGCCAA CAGCCCACTC
TACGACCTGG CACCCAGCGA CCTGCACCAC CACCAGGACC TCGAGATCAT CGTCATCCTG
GAAGGCGTGG TGGAAACCAC GGGCATCACC ACCCAGGCCC GCACCTCCTA CCTGGCCGAT
GAGATCCTGT GGGGCCAGCG CTTTGTGCCC ATTGTAGCTG AGGAGGACGG ACGTTACTCT
GTGGACTACT CCAAGTTTGG CAACACCGTC AAAGTGCCCA CACCACTCTG CACGGCCCGC
CAGCTTGATG AGGACCACAG CCTACTGGAA GCTCTGACCC TCGCCTCAGC CCGCGGGCCC
CTGCGCAAGC GCAGCGTGCC CATGGCCAAG GCCAAGCCCA AGTTCAGCAT CTCTCCAGAT
TCCCTGTCCT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

Patient with iDEND syndrome-related mutation
Diabetes Care 37 (6), E123-E124 (2014)
Prado-Carro AM, Calzada-Hernandez J, Marin S, Cardona-Hernandez R, Oriola J, Nicolas M and Ramon-Krauel M.


book

Clinical characteristics and phenotype-genotype analysis in Turkish patients with congenital hyperinsulinism; predominance of recessive KATP channel mutations
Eur. J. Endocrinol. 170 (6), 885-892 (2014)
Demirbilek H, Arya VB, Ozbek MN, Akinci A, Dogan M, Demirel F, Houghton J, Kaba S, Guzel F, Baran RT, Unal S, Tekkes S, Flanagan SE, Ellard S and Hussain K.


book

KCNJ11 gene mutation analysis on nine Chinese patients with type 1B diabetes diagnosed before 3 years of age
J. Pediatr. Endocrinol. Metab. 27 (5-6), 519-523 (2014)
Sang,Y., Yang,W., Yan,J. and Wu,Y.


book

Cloning of the promoters for the beta-cell ATP-sensitive K-channel subunits Kir6.2 and SUR1
Diabetes 47 (8), 1274-1280 (1998)
Ashfield R and Ashcroft SJ.


book

Sequence variations in the human Kir6.2 gene, a subunit of the beta-cell ATP-sensitive K-channel: no association with NIDDM in while Caucasian subjects or evidence of abnormal function when expressed in vitro
Diabetologia 39 (10), 1233-1236 (1996)
Sakura H, Wat N, Horton V, Millns H, Turner RC and Ashcroft FM.


book

Identification of microsatellite markers near the human genes encoding the beta-cell ATP-sensitive K+ channel and linkage studies with NIDDM in Japanese
Diabetes 45 (2), 267-269 (1996)
Iwasaki N, Kawamura M, Yamagata K, Cox NJ, Karibe S, Ohgawara H, Inagaki N, Seino S, Bell GI and Omori Y.


book

Reconstitution of IKATP: an inward rectifier subunit plus the sulfonylurea receptor
Science 270 (5239), 1166-1170 (1995)
Inagaki N, Gonoi T, Clement JP 4th, Namba N, Inazawa J, Gonzalez G, Aguilar-Bryan L, Seino S and Bryan J.


book

Homozygosity mapping, to chromosome 11p, of the gene for familial persistent hyperinsulinemic hypoglycemia of infancy
Am. J. Hum. Genet. 56 (2), 416-421 (1995)
Thomas PM, Cote GJ, Hallman DM and Mathew PM.


book

Permanent Neonatal Diabetes Mellitus
(in) Pagon RA, Adam MP, Ardinger HH, Bird TD, Dolan CR, Fong CT, Smith RJH and Stephens K (Eds.); GENEREVIEWS(R); (1993)
De Leon,D.D. and Stanley,C.A.


book

Familial Hyperinsulinism
(in) Pagon RA, Adam MP, Ardinger HH, Bird TD, Dolan CR, Fong CT, Smith RJH and Stephens K (Eds.); GENEREVIEWS(R); (1993)
Glaser,B.


 
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