||ORF Nucleotide Sequence (Length: 1935bp)
||pcDNA3.1-C-(k)DYK or customized vector
|Tag on pcDNA3.1-C-(k)DYK
||C terminal DYKDDDDK tags
|ORF Insert Method
||CloneEZ® Seamless cloning technology
||Homo sapiens (human)
||keratin, type II cytoskeletal 1
||REVIEWED REFSEQ: This record has been curated by NCBI staff in
collaboration with Michael Rogers. The reference sequence was
derived from DB112126.1, BC063697.1 and AC055716.24.
This sequence is a reference standard in the RefSeqGene project.
On Dec 14, 2006 this sequence version replaced gi:17318568.
Summary: The protein encoded by this gene is a member of the
keratin gene family. The type II cytokeratins consist of basic or
neutral proteins which are arranged in pairs of heterotypic keratin
chains coexpressed during differentiation of simple and stratified
epithelial tissues. This type II cytokeratin is specifically
expressed in the spinous and granular layers of the epidermis with
family member KRT10 and mutations in these genes have been
associated with bullous congenital ichthyosiform erythroderma. The
type II cytokeratins are clustered in a region of chromosome
12q12-q13. [provided by RefSeq, Jul 2008].
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
Transcript exon combination :: BC063697.1, M10938.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
COMPLETENESS: complete on the 3' end.