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KRT6A keratin 6A, type II [Homo sapiens (human)]

Gene Symbol KRT6A
Entrez Gene ID 3853
Full Name keratin 6A, type II
Synonyms CK6A, CK6C, CK6D, K6A, K6C, K6D, KRT6C, KRT6D, PC3
General protein information
Preferred Names
keratin, type II cytoskeletal 6A
Names
keratin, type II cytoskeletal 6A
cytokeratin 6A
cytokeratin 6C
cytokeratin 6D
type-II keratin Kb6
keratin, epidermal type II, K6A
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

12

12q13.13

Summary The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin (KRT6) have been identified; the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. This KRT6 gene in particular encodes the most abundant isoform. Mutations in these genes have been associated with pachyonychia congenita. In addition, peptides from the C-terminal region of the protein have antimicrobial activity against bacterial pathogens. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq, Oct 2014]. lac of sum
Disorder MIM:

148041

Disorder Html: Pachyonychia congenita, Jadassohn-Lewandowsky type, 167200 (3)
CloneID RefSeq Accession Definition **Vector *Turnaround time Price
OHu19164 NM_005554 Homo sapiens keratin 6A, type II (KRT6A), mRNA. pcDNA3.1-C-(k)DYK In stock 5-7 Starting from $99.00

*Business Day
**You may select a custom vector to replace pcDNA3.1-C-(k)DYK after clone is added to cart.



CloneID OHu19164D
Sequence Information ORF Nucleotide Sequence (Length: 1695bp)
Protein sequence
SNP
Vector pcDNA3.1-C-(k)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1-C-(k)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product keratin, type II cytoskeletal 6A
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff in collaboration with Michael Rogers. The reference sequence was derived from DA451441.1, BC008807.2 and BG059253.1. This sequence is a reference standard in the RefSeqGene project. On or before Feb 27, 2007 this sequence version replaced gi:17505188, gi:17505186. Summary: The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin (KRT6) have been identified; the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. This KRT6 gene in particular encodes the most abundant isoform. Mutations in these genes have been associated with pachyonychia congenita. In addition, peptides from the C-terminal region of the protein have antimicrobial activity against bacterial pathogens. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq, Oct 2014]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##RefSeq-Attributes-START## Protein has antimicrobial activity :: PMID: 23006328 ##RefSeq-Attributes-END## ##Evidence-Data-START## Transcript exon combination :: BC014152.2, BC008807.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2147975, SAMEA2156670 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
ATGGCCAGCA CATCCACCAC CATCAGGAGC CACAGCAGCA GCCGCCGGGG TTTCAGTGCC 
AACTCAGCCA GGCTCCCTGG GGTCAGCCGC TCTGGCTTCA GCAGCGTCTC CGTGTCCCGC
TCCAGGGGCA GTGGTGGCCT GGGTGGTGCA TGTGGAGGAG CTGGCTTTGG CAGCCGCAGT
CTGTATGGCC TGGGGGGCTC CAAGAGGATC TCCATTGGAG GGGGCAGCTG TGCCATCAGT
GGCGGCTATG GCAGCAGAGC CGGAGGCAGC TATGGCTTTG GTGGCGCCGG GAGTGGATTT
GGTTTCGGTG GTGGAGCCGG CATTGGCTTT GGTCTGGGTG GTGGAGCCGG CCTTGCTGGT
GGCTTTGGGG GCCCTGGCTT CCCTGTGTGC CCCCCTGGAG GCATCCAAGA GGTCACCGTC
AACCAGAGTC TCCTGACTCC CCTCAACCTG CAAATCGATC CCACCATCCA GCGGGTGCGG
GCTGAGGAGC GTGAACAGAT CAAGACCCTC AACAACAAGT TTGCCTCCTT CATCGACAAG
GTGCGGTTCC TGGAGCAGCA GAACAAGGTT CTGGAAACAA AGTGGACCCT GCTGCAGGAG
CAGGGCACCA AGACTGTGAG GCAGAACCTG GAGCCGTTGT TCGAGCAGTA CATCAACAAC
CTCAGGAGGC AGCTGGACAG CATTGTCGGG GAACGGGGCC GCCTGGACTC AGAGCTCAGA
GGCATGCAGG ACCTGGTGGA GGACTTCAAG AACAAATATG AGGATGAAAT CAACAAGCGC
ACAGCAGCAG AGAATGAATT TGTGACTCTG AAGAAGGATG TGGATGCTGC CTACATGAAC
AAGGTTGAAC TGCAAGCCAA GGCAGACACT CTCACAGACG AGATCAACTT CCTGAGAGCC
TTGTATGATG CAGAGCTGTC CCAGATGCAG ACCCACATCT CAGACACATC TGTGGTGCTG
TCCATGGACA ACAACCGCAA CCTGGACCTG GACAGCATCA TCGCTGAGGT CAAGGCCCAA
TATGAGGAGA TTGCTCAGAG AAGCCGGGCT GAGGCTGAGT CCTGGTACCA GACCAAGTAC
GAGGAGCTGC AGGTCACAGC AGGCAGACAT GGGGACGACC TGCGCAACAC CAAGCAGGAG
ATTGCTGAGA TCAACCGCAT GATCCAGAGG CTGAGATCTG AGATCGACCA CGTCAAGAAG
CAGTGCGCCA ACCTGCAGGC CGCCATTGCT GATGCTGAGC AGCGTGGGGA GATGGCCCTC
AAGGATGCCA AGAACAAGCT GGAAGGGCTG GAGGATGCCC TGCAGAAGGC CAAGCAGGAC
CTGGCCCGGC TGCTGAAGGA GTACCAGGAG CTGATGAATG TCAAGCTGGC CCTGGACGTG
GAGATCGCCA CCTACCGCAA GCTGCTGGAG GGTGAGGAGT GCAGGCTGAA TGGCGAAGGC
GTTGGACAAG TCAACATCTC TGTGGTGCAG TCCACCGTCT CCAGTGGCTA TGGCGGTGCC
AGTGGTGTCG GCAGTGGCTT AGGCCTGGGT GGAGGAAGCA GCTACTCCTA TGGCAGTGGT
CTTGGCGTTG GAGGTGGCTT CAGTTCCAGC AGTGGCAGAG CCATTGGGGG TGGCCTCAGC
TCTGTTGGAG GCGGCAGTTC CACCATCAAG TACACCACCA CCTCCTCCTC CAGCAGGAAG
AGCTATAAGC ACTAA
The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.
RefSeqNP_005545.1
CDS210..1904
Misc Feature(1)114..116(+)
Misc Feature(2)213..695(+)
Misc Feature(3)213..215(+)
Misc Feature(4)693..1634(+)
Misc Feature(5)696..1625(+)
Misc Feature(6)696..803(+)
Misc Feature(7)804..860(+)
Misc Feature(8)861..1136(+)
Misc Feature(9)1137..1208(+)
Misc Feature(10)1209..1625(+)
Misc Feature(11)1317..>1652(+)
Misc Feature(12)1449..1451(+)
Misc Feature(13)1626..1901(+)
Exon (1)1..749
Gene:KRT6A
Gene Synonym:
Exon (2)750..964
Gene:KRT6A
Gene Synonym:
Exon (3)965..1025
Gene:KRT6A
Gene Synonym:
Exon (4)1026..1121
Gene:KRT6A
Gene Synonym:
Exon (5)1122..1286
Gene:KRT6A
Gene Synonym:
Exon (6)1287..1412
Gene:KRT6A
Gene Synonym:
Exon (7)1413..1633
Gene:KRT6A
Gene Synonym:
Exon (8)1634..1668
Gene:KRT6A
Gene Synonym:
Exon (9)1669..2450
Gene:KRT6A
Gene Synonym:
Translation
Position Chain Variation Link
32 32 a, g dbSNP:777096774
69 69 c, t dbSNP:571319747
74 74 g, t dbSNP:551513949
98 98 c, t dbSNP:528286530
150 150 c, t dbSNP:7313756
158 158 c, t dbSNP:752987349
163 163 g, t dbSNP:766150726
164 164 c, g, t dbSNP:773068051
171 171 c, g dbSNP:549239484
179 179 a, g dbSNP:761179922
180 180 c, t dbSNP:773891630
187 187 a, c dbSNP:768116028
190 190 c, t dbSNP:748933825
191 191 c, t dbSNP:2939599
194 194 c, t dbSNP:529208990
196 196 a, c dbSNP:746262529
215 215 c, t dbSNP:11540285
223 223 c, t dbSNP:563614469
229 229 a, c dbSNP:757757524
231 231 a, g dbSNP:372264347
236 236 a, g dbSNP:747506929
239 239 c, t dbSNP:369229884
240 240 c, t dbSNP:758533268
249 249 a, g dbSNP:752862612
252 252 c, t dbSNP:543383074
253 253 a, g, t dbSNP:533157590
255 255 c, t dbSNP:767267061
256 256 a, g dbSNP:761780446
259 259 a, g dbSNP:774212057
265 265 a, g dbSNP:201201647
271 271 a, g dbSNP:17845411
285 285 c, t dbSNP:775241916
287 287 c, t dbSNP:769588636
289 289 a, g dbSNP:759307145
290 290 a, g dbSNP:777020530
291 291 g, t dbSNP:771263689
295 295 a, g dbSNP:747540470
296 296 a, c dbSNP:778160585
297 297 c, t dbSNP:368524604
310 310 a, g dbSNP:555709018
314 314 c, t dbSNP:779059221
315 315 a, g dbSNP:755172711
320 320 c, t dbSNP:754048248
321 321 a, c, g dbSNP:757013535
327 327 c, t dbSNP:375671619
328 328 a, g, t dbSNP:762500774
333 333 a, c dbSNP:752229219
337 337 g, t dbSNP:764877666
347 347 c, t dbSNP:542426806
353 353 a, t dbSNP:776207246
355 355 a, g dbSNP:771272231
356 356 c, t dbSNP:367621240
369 369 c, g dbSNP:111569932
372 372 a, g dbSNP:374545789
382 382 a, g dbSNP:772590643
385 385 a, g dbSNP:748703748
389 389 c, t dbSNP:199677961
390 390 c, t dbSNP:201545589
392 392 a, g dbSNP:200231214
398 398 a, c dbSNP:780141851
406 406 -, g dbSNP:774419421
407 407 a, c dbSNP:201927660
417 417 a, t dbSNP:757036849
418 418 c, t dbSNP:751333405
419 419 a, c dbSNP:777756079
424 424 c, t dbSNP:571307633
442 442 c, t dbSNP:557885841
451 451 g, t dbSNP:764824336
453 453 a, g dbSNP:758984854
470 470 c, t dbSNP:534450631
471 471 a, g dbSNP:201156103
494 494 c, t dbSNP:765981606
495 495 a, g dbSNP:372112762
497 497 c, t dbSNP:368455216
498 498 a, g dbSNP:200254647
503 503 g, t dbSNP:565853825
516 516 a, g dbSNP:548869463
518 518 c, t dbSNP:774851675
527 527 c, g dbSNP:768654383
528 528 a, g dbSNP:749357737
533 533 c, t dbSNP:775731695
535 535 c, g dbSNP:769880941
536 536 c, t dbSNP:746138114
541 541 a, g dbSNP:681063
543 543 c, t dbSNP:374275838
547 547 a, g dbSNP:748044525
557 557 c, t dbSNP:779001561
558 558 a, g dbSNP:754474806
570 570 a, g dbSNP:753315066
572 572 c, t dbSNP:370840968
574 574 c, t dbSNP:549671322
576 576 a, g dbSNP:750145364
577 577 a, g dbSNP:767856687
580 580 a, g dbSNP:762168782
583 583 c, t dbSNP:774798543
584 584 c, t dbSNP:200967849
590 590 c, t dbSNP:763563881
593 593 c, t dbSNP:775397240
598 598 a, g, t dbSNP:746061780
599 599 c, t dbSNP:777003645
601 601 c, t dbSNP:771929106
602 602 a, c dbSNP:184577522
603 603 a, c, t dbSNP:564186303
605 605 a, t dbSNP:377196186
618 618 a, g dbSNP:779426966
623 623 a, c, g dbSNP:750009901
626 626 c, g, t dbSNP:1707768
627 627 a, g dbSNP:201221663
639 639 c, g dbSNP:764555290
641 641 c, t dbSNP:763361891
648 648 c, t dbSNP:753301674
655 655 a, g dbSNP:765170804
657 657 c, t dbSNP:759695664
661 661 a, g dbSNP:776956575
665 665 c, t dbSNP:1707767
668 668 c, t dbSNP:761031340
669 669 c, g, t dbSNP:11836126
672 672 a, g dbSNP:749170462
678 678 a, c dbSNP:780056287
679 679 a, g dbSNP:769144066
681 681 a, c, g dbSNP:201896183
682 682 a, g dbSNP:745403820
683 683 a, g dbSNP:780728456
684 684 g, t dbSNP:756872577
686 686 g, t dbSNP:751275315
688 688 a, g dbSNP:777982391
689 689 g, t dbSNP:758800753
692 692 c, t dbSNP:711317
696 696 a, g dbSNP:267607464
700 700 a, c, g dbSNP:62635293
702 702 a, g dbSNP:759642583
704 704 a, g dbSNP:376545
706 706 a, c dbSNP:267607460
709 709 a, g, t dbSNP:57126929
717 717 c, t dbSNP:57448541
720 720 a, g, t dbSNP:62635294
721 721 a, c, g dbSNP:58556099
722 722 a, c dbSNP:59685571
723 723 -, aac dbSNP:267607459
725 725 -, caa dbSNP:606231214
729 729 c, g, t dbSNP:28933087
730 730 c, g, t dbSNP:61145796
735 735 c, t dbSNP:59642296
737 737 c, t dbSNP:760975660
742 742 a, t dbSNP:267607461
743 743 c, t dbSNP:773542280
746 746 c, t dbSNP:768279471
754 754 a, g dbSNP:367973525
759 759 c, g dbSNP:761989428
761 761 a, g dbSNP:775323190
776 776 a, g dbSNP:7298145
777 777 a, g dbSNP:371455502
780 780 c, t dbSNP:776558781
782 782 a, g dbSNP:770357838
785 785 a, c dbSNP:764573648
788 788 a, c, g dbSNP:368555326
804 804 a, c dbSNP:747800266
813 813 a, g dbSNP:779419676
823 823 c, g dbSNP:755451843
825 825 a, g dbSNP:561751156
837 837 a, c, g dbSNP:144401677
838 838 g, t dbSNP:756211638
840 840 a, g dbSNP:575695802
845 845 a, g dbSNP:371264380
851 851 c, t dbSNP:767532911
862 862 c, t dbSNP:757497115
866 866 a, c dbSNP:751783525
867 867 a, g dbSNP:764950648
868 868 a, c dbSNP:759327345
870 870 a, c, t dbSNP:368436863
871 871 g, t dbSNP:760581591
874 874 a, g dbSNP:772751520
877 877 a, g dbSNP:200977095
879 879 c, g dbSNP:370627541
880 880 a, c dbSNP:774161759
881 881 g, t dbSNP:769077040
882 882 a, c dbSNP:749702673
889 889 a, g dbSNP:200763387
891 891 a, g dbSNP:576668881
893 893 c, t dbSNP:201568563
895 895 c, t dbSNP:781318215
896 896 c, g, t dbSNP:201950477
897 897 a, c, g dbSNP:754716072
898 898 a, g dbSNP:759709861
903 903 a, c, g, t dbSNP:760660499
904 904 a, g dbSNP:149632009
905 905 c, g dbSNP:766998826
907 907 -, g dbSNP:769620246
908 908 c, t dbSNP:761237289
909 909 c, t dbSNP:370031805
910 910 a, g dbSNP:779699121
912 912 a, c dbSNP:762731553
914 914 a, g dbSNP:201153696
920 920 a, g dbSNP:199531479
924 924 c, t dbSNP:770110646
926 926 c, g dbSNP:534124939
927 927 a, g dbSNP:199528324
930 930 a, g dbSNP:201663666
931 931 a, g dbSNP:199613662
935 935 g, t dbSNP:777881234
937 937 a, g dbSNP:758589282
943 943 g, t dbSNP:752985009
945 945 a, g dbSNP:779886537
947 947 a, g dbSNP:755878651
949 949 a, c dbSNP:538266765
953 953 c, g dbSNP:569325385
954 954 c, t dbSNP:201142403
957 957 a, c dbSNP:751080524
968 968 g, t dbSNP:781079162
969 969 a, g dbSNP:370032292
971 971 a, g dbSNP:751602159
972 972 g, t dbSNP:763636332
974 974 c, t dbSNP:757987091
981 981 a, c dbSNP:752353221
982 982 a, c dbSNP:764818801
987 987 a, c, t dbSNP:776832787
988 988 a, g dbSNP:376821206
991 991 c, t dbSNP:761158516
995 995 a, g dbSNP:373623240
996 996 a, g dbSNP:369296947
1002 1002 a, g dbSNP:547136077
1005 1005 c, g dbSNP:774586645
1014 1014 a, g dbSNP:768741155
1015 1015 c, t dbSNP:752783156
1019 1019 a, g dbSNP:749589808
1025 1025 a, g dbSNP:780833562
1027 1027 a, g dbSNP:759876129
1028 1028 c, t dbSNP:12578949
1031 1031 g, t dbSNP:368725695
1036 1036 c, t dbSNP:747979011
1040 1040 c, t dbSNP:778915093
1048 1048 a, g dbSNP:768011751
1053 1053 g, t dbSNP:748856563
1054 1054 g, t dbSNP:574553595
1069 1069 a, g dbSNP:755734415
1071 1071 a, g dbSNP:376480528
1075 1075 a, t dbSNP:750145556
1082 1082 c, t dbSNP:554838409
1083 1083 a, g dbSNP:757641086
1084 1084 c, t dbSNP:751967999
1088 1088 a, c, t dbSNP:398542
1091 1091 a, g dbSNP:544561120
1101 1101 c, t dbSNP:765478998
1109 1109 a, c, t dbSNP:777009530
1116 1116 g, t dbSNP:771697147
1117 1117 a, t dbSNP:761700634
1119 1119 g, t dbSNP:774110108
1126 1126 a, t dbSNP:762867388
1129 1129 a, c dbSNP:775408129
1130 1130 c, t dbSNP:551731110
1131 1131 -, c dbSNP:35052919
1138 1138 -, a dbSNP:779559171
1148 1148 a, c dbSNP:374415163
1156 1156 c, g dbSNP:201208927
1160 1160 c, t dbSNP:432834
1169 1169 a, c, g dbSNP:370500
1171 1171 c, t dbSNP:372287870
1172 1172 a, c dbSNP:546415971
1173 1173 a, g dbSNP:748600865
1181 1181 a, c, t dbSNP:368061297
1185 1185 c, t dbSNP:373927281
1186 1186 a, g dbSNP:753948082
1190 1190 c, g, t dbSNP:756357205
1204 1204 a, g dbSNP:750672667
1206 1206 a, g dbSNP:370221157
1211 1211 c, t dbSNP:762764830
1212 1212 a, g dbSNP:140989962
1213 1213 c, g dbSNP:374286502
1217 1217 a, g dbSNP:759509125
1226 1226 a, c dbSNP:776200039
1232 1232 c, t dbSNP:770403240
1234 1234 a, g dbSNP:200194396
1245 1245 c, g dbSNP:772746386
1247 1247 c, g dbSNP:772528079
1250 1250 a, g dbSNP:15923
1250 1250 a, g dbSNP:187791200
1253 1253 c, t dbSNP:779470611
1254 1254 a, c, t dbSNP:1053699
1255 1255 a, g dbSNP:780171825
1274 1274 a, g dbSNP:138331383
1282 1282 a, c, t dbSNP:750615661
1283 1283 a, c dbSNP:1132953
1289 1289 c, t dbSNP:374430447
1290 1290 a, c, g dbSNP:369911781
1293 1293 a, g dbSNP:747166487
1302 1302 a, g dbSNP:376633846
1308 1308 a, g dbSNP:754754199
1311 1311 a, g, t dbSNP:779941716
1317 1317 c, t dbSNP:756003826
1318 1318 a, g dbSNP:750446404
1322 1322 a, g dbSNP:767082165
1323 1323 a, g dbSNP:756836784
1325 1325 c, t dbSNP:372043088
1328 1328 c, t dbSNP:763812556
1332 1332 c, t dbSNP:368272363
1333 1333 a, g dbSNP:775710030
1340 1340 a, c, g dbSNP:374230378
1347 1347 a, g dbSNP:777127235
1351 1351 c, t dbSNP:201750033
1365 1365 c, t dbSNP:747115156
1366 1366 a, g dbSNP:371739150
1369 1369 a, t dbSNP:772154935
1378 1378 a, g dbSNP:373694426
1384 1384 a, g dbSNP:779703309
1394 1394 c, t dbSNP:755953809
1395 1395 a, g dbSNP:745737972
1399 1399 a, c dbSNP:781313399
1400 1400 c, t dbSNP:202094973
1407 1407 a, c dbSNP:199654876
1414 1414 a, g dbSNP:774391774
1415 1415 c, t dbSNP:768888133
1416 1416 a, g dbSNP:372637888
1420 1420 a, g dbSNP:776551928
1430 1430 c, t dbSNP:369027797
1431 1431 a, g, t dbSNP:562064061
1432 1432 c, t dbSNP:201401681
1433 1433 c, t dbSNP:747673159
1434 1434 a, t dbSNP:778326332
1437 1437 a, g dbSNP:754623653
1438 1438 c, t dbSNP:531954336
1442 1442 c, t dbSNP:374013120
1445 1445 c, t dbSNP:546570448
1446 1446 c, g dbSNP:750858953
1452 1452 c, t dbSNP:369800257
1453 1453 a, g dbSNP:61730612
1466 1466 a, c dbSNP:564140506
1469 1469 c, t dbSNP:764325509
1473 1473 a, g dbSNP:763207529
1474 1474 a, g dbSNP:775857653
1478 1478 c, t dbSNP:145246640
1482 1482 a, c dbSNP:540683446
1488 1488 c, t dbSNP:772929769
1491 1491 a, g dbSNP:371779435
1494 1494 c, g dbSNP:190973167
1495 1495 a, g, t dbSNP:768169678
1499 1499 a, g, t dbSNP:368052661
1505 1505 c, t dbSNP:756425548
1509 1509 -, c dbSNP:766852744
1511 1511 a, g dbSNP:746226004
1512 1512 c, t dbSNP:267607467
1513 1513 a, g dbSNP:376008138
1523 1523 a, g dbSNP:757765511
1527 1527 g, t dbSNP:752017402
1530 1530 c, t dbSNP:764200849
1534 1534 c, g dbSNP:758579660
1535 1535 c, t dbSNP:555046513
1536 1536 c, t dbSNP:62617089
1537 1537 a, g dbSNP:186117617
1547 1547 a, g dbSNP:201046313
1549 1549 a, g dbSNP:773056995
1551 1551 a, t dbSNP:767275249
1552 1552 a, c dbSNP:761754085
1559 1559 c, g dbSNP:774279852
1568 1568 c, t dbSNP:1053703
1571 1571 c, g dbSNP:768118281
1578 1578 a, c, g, t dbSNP:367788212
1580 1580 c, g dbSNP:371399727
1586 1586 c, t dbSNP:368523101
1587 1587 a, g, t dbSNP:180935064
1589 1589 a, g dbSNP:781559230
1590 1590 a, c, g dbSNP:267607468
1594 1594 a, g, t dbSNP:57629991
1595 1595 a, c, t dbSNP:370853930
1596 1596 c, g dbSNP:267607462
1599 1599 a, c dbSNP:61293647
1602 1602 c, t dbSNP:267607463
1603 1603 a, g dbSNP:267607469
1605 1605 c, t dbSNP:778445643
1606 1606 a, g dbSNP:376556886
1607 1607 c, t dbSNP:752793452
1612 1612 a, c, t dbSNP:59018888
1614 1614 c, t dbSNP:779201808
1615 1615 c, g, t dbSNP:57052654
1619 1619 a, g dbSNP:755215162
1620 1620 g, t dbSNP:554108795
1622 1622 c, t dbSNP:1132960
1623 1623 a, g dbSNP:60554162
1625 1625 c, g dbSNP:267607470
1636 1636 g, t dbSNP:772579442
1640 1640 c, t dbSNP:776400665
1643 1643 a, c, t dbSNP:768734860
1644 1644 a, g dbSNP:369674600
1648 1648 g, t dbSNP:780226920
1649 1649 c, t dbSNP:756329465
1650 1650 a, g dbSNP:201376827
1651 1651 c, t dbSNP:777474369
1658 1658 a, g dbSNP:372218481
1663 1663 a, g dbSNP:752580249
1664 1664 c, t dbSNP:200693998
1665 1665 a, c, g dbSNP:150913083
1673 1673 a, g dbSNP:3194315
1674 1674 a, g dbSNP:769828086
1683 1683 a, g dbSNP:759582849
1685 1685 c, g, t dbSNP:200390705
1686 1686 a, g dbSNP:201432146
1692 1692 a, g dbSNP:761366760
1699 1699 a, t dbSNP:778505927
1700 1700 c, t dbSNP:768509690
1703 1703 a, c, t dbSNP:374239834
1704 1704 a, g dbSNP:370904942
1705 1705 a, g dbSNP:749927485
1708 1708 c, g dbSNP:780904452
1712 1712 c, t dbSNP:567110834
1718 1718 c, t dbSNP:376504088
1719 1719 a, g dbSNP:764320645
1720 1720 -, g dbSNP:267607471
1720 1720 a, g dbSNP:763410366
1732 1732 c, g dbSNP:753045584
1733 1733 c, t dbSNP:373751709
1734 1734 c, t dbSNP:760095581
1736 1736 a, g dbSNP:776689308
1750 1750 a, g dbSNP:771003518
1752 1752 c, t dbSNP:760750409
1755 1755 c, t dbSNP:773505269
1760 1760 c, t dbSNP:768293895
1768 1768 a, g dbSNP:749077023
1769 1769 a, c, t dbSNP:527286523
1773 1773 g, t dbSNP:745863037
1774 1774 a, g dbSNP:780777904
1775 1775 c, t dbSNP:756818131
1776 1776 a, g, t dbSNP:62617088
1780 1780 a, g dbSNP:758038715
1782 1782 a, g dbSNP:753048551
1784 1784 c, t dbSNP:1053718
1787 1787 c, t dbSNP:759970854
1790 1790 c, t dbSNP:1053722
1790 1790 c, t dbSNP:754357440
1802 1802 c, t dbSNP:1053727
1804 1804 a, g dbSNP:766321052
1811 1811 a, c dbSNP:376474194
1813 1813 a, c, t dbSNP:1053734
1816 1816 a, g dbSNP:376333253
1817 1817 a, g dbSNP:775417845
1822 1822 a, c, g dbSNP:200198490
1823 1823 c, t dbSNP:745756325
1831 1831 c, t dbSNP:776745356
1834 1834 c, t dbSNP:562446847
1841 1841 c, t dbSNP:545943389
1842 1842 a, g dbSNP:201826031
1843 1843 a, g dbSNP:758066110
1859 1859 a, g, t dbSNP:577005792
1861 1861 a, g dbSNP:560395552
1864 1864 c, g dbSNP:11540301
1867 1867 a, c dbSNP:766876318
1870 1870 a, c dbSNP:756625699
1871 1871 c, g dbSNP:750501003
1873 1873 c, g dbSNP:767557297
1880 1880 c, t dbSNP:762057239
1883 1883 c, t dbSNP:774724443
1884 1884 a, g dbSNP:201823807
1887 1887 -, aaga dbSNP:753106368
1890 1890 a, t dbSNP:759378508
1895 1895 c, t dbSNP:1053740
1903 1903 a, g, t dbSNP:1053741
1904 1904 -, aa dbSNP:767913443
1909 1909 c, t dbSNP:746987648
1910 1910 a, g, t dbSNP:200885123
1912 1912 c, g dbSNP:371708620
1913 1913 c, t dbSNP:3204925
1914 1914 g, t dbSNP:778568624
1916 1916 c, t dbSNP:1053745
1921 1921 c, t dbSNP:554970934
1923 1923 c, t dbSNP:202133726
1924 1924 a, g dbSNP:1053748
1928 1928 c, g dbSNP:376487686
1930 1930 a, g dbSNP:372901135
1932 1932 a, g dbSNP:199818997
1933 1933 c, g dbSNP:201116384
1935 1935 c, t dbSNP:751733053
1940 1940 a, g dbSNP:764392961
1942 1942 c, t dbSNP:567000265
1944 1944 c, t dbSNP:11544884
1945 1945 c, t dbSNP:3194366
1951 1951 a, g dbSNP:770184809
1954 1954 a, t dbSNP:1053770
1963 1963 c, g dbSNP:547249637
1977 1977 c, t dbSNP:548777854
1978 1978 c, t dbSNP:1053795
1980 1980 g, t dbSNP:28667515
1983 1983 c, t dbSNP:547736440
1986 1986 c, t dbSNP:1053803
2003 2003 c, t dbSNP:372195223
2009 2009 c, t dbSNP:1063922
2010 2010 c, g dbSNP:1053825
2015 2015 a, g dbSNP:1063923
2028 2028 g, t dbSNP:1053854
2032 2032 a, g dbSNP:1053857
2045 2045 c, t dbSNP:1063931
2059 2059 c, t dbSNP:562728568
2062 2062 c, t dbSNP:11544880
2065 2065 a, c dbSNP:181234451
2067 2067 a, g dbSNP:1063939
2071 2071 a, c dbSNP:3204962
2093 2093 c, t dbSNP:573922620
2096 2096 c, g dbSNP:76154868
2146 2146 -, tt dbSNP:397785715
2147 2147 -, tt dbSNP:10656649
2184 2184 a, t dbSNP:189193366
2187 2187 c, t dbSNP:11544881
2208 2208 a, g dbSNP:540404622
2283 2283 a, c dbSNP:140939076
2324 2324 a, c dbSNP:544575151
2326 2326 c, g dbSNP:575748573
2331 2331 a, g dbSNP:559005284
2352 2352 a, g dbSNP:538784486
2372 2372 c, g dbSNP:760481080
2377 2377 c, t dbSNP:573369129
2381 2381 a, t dbSNP:750133703
2409 2409 a, g dbSNP:1054122
2412 2412 c, g dbSNP:1133153
2430 2430 a, g dbSNP:571302636
2435 2435 a, g dbSNP:75743814

Target ORF information:

RefSeq Version NM_005554
Organism Homo sapiens (human)
Definition Homo sapiens keratin 6A, type II (KRT6A), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1-C-(k)DYK
NM_005554

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
ATGGCCAGCA CATCCACCAC CATCAGGAGC CACAGCAGCA GCCGCCGGGG TTTCAGTGCC 
AACTCAGCCA GGCTCCCTGG GGTCAGCCGC TCTGGCTTCA GCAGCGTCTC CGTGTCCCGC
TCCAGGGGCA GTGGTGGCCT GGGTGGTGCA TGTGGAGGAG CTGGCTTTGG CAGCCGCAGT
CTGTATGGCC TGGGGGGCTC CAAGAGGATC TCCATTGGAG GGGGCAGCTG TGCCATCAGT
GGCGGCTATG GCAGCAGAGC CGGAGGCAGC TATGGCTTTG GTGGCGCCGG GAGTGGATTT
GGTTTCGGTG GTGGAGCCGG CATTGGCTTT GGTCTGGGTG GTGGAGCCGG CCTTGCTGGT
GGCTTTGGGG GCCCTGGCTT CCCTGTGTGC CCCCCTGGAG GCATCCAAGA GGTCACCGTC
AACCAGAGTC TCCTGACTCC CCTCAACCTG CAAATCGATC CCACCATCCA GCGGGTGCGG
GCTGAGGAGC GTGAACAGAT CAAGACCCTC AACAACAAGT TTGCCTCCTT CATCGACAAG
GTGCGGTTCC TGGAGCAGCA GAACAAGGTT CTGGAAACAA AGTGGACCCT GCTGCAGGAG
CAGGGCACCA AGACTGTGAG GCAGAACCTG GAGCCGTTGT TCGAGCAGTA CATCAACAAC
CTCAGGAGGC AGCTGGACAG CATTGTCGGG GAACGGGGCC GCCTGGACTC AGAGCTCAGA
GGCATGCAGG ACCTGGTGGA GGACTTCAAG AACAAATATG AGGATGAAAT CAACAAGCGC
ACAGCAGCAG AGAATGAATT TGTGACTCTG AAGAAGGATG TGGATGCTGC CTACATGAAC
AAGGTTGAAC TGCAAGCCAA GGCAGACACT CTCACAGACG AGATCAACTT CCTGAGAGCC
TTGTATGATG CAGAGCTGTC CCAGATGCAG ACCCACATCT CAGACACATC TGTGGTGCTG
TCCATGGACA ACAACCGCAA CCTGGACCTG GACAGCATCA TCGCTGAGGT CAAGGCCCAA
TATGAGGAGA TTGCTCAGAG AAGCCGGGCT GAGGCTGAGT CCTGGTACCA GACCAAGTAC
GAGGAGCTGC AGGTCACAGC AGGCAGACAT GGGGACGACC TGCGCAACAC CAAGCAGGAG
ATTGCTGAGA TCAACCGCAT GATCCAGAGG CTGAGATCTG AGATCGACCA CGTCAAGAAG
CAGTGCGCCA ACCTGCAGGC CGCCATTGCT GATGCTGAGC AGCGTGGGGA GATGGCCCTC
AAGGATGCCA AGAACAAGCT GGAAGGGCTG GAGGATGCCC TGCAGAAGGC CAAGCAGGAC
CTGGCCCGGC TGCTGAAGGA GTACCAGGAG CTGATGAATG TCAAGCTGGC CCTGGACGTG
GAGATCGCCA CCTACCGCAA GCTGCTGGAG GGTGAGGAGT GCAGGCTGAA TGGCGAAGGC
GTTGGACAAG TCAACATCTC TGTGGTGCAG TCCACCGTCT CCAGTGGCTA TGGCGGTGCC
AGTGGTGTCG GCAGTGGCTT AGGCCTGGGT GGAGGAAGCA GCTACTCCTA TGGCAGTGGT
CTTGGCGTTG GAGGTGGCTT CAGTTCCAGC AGTGGCAGAG CCATTGGGGG TGGCCTCAGC
TCTGTTGGAG GCGGCAGTTC CACCATCAAG TACACCACCA CCTCCTCCTC CAGCAGGAAG
AGCTATAAGC ACTAA

The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.