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KRT6B keratin 6B, type II [Homo sapiens (human)]

Gene Symbol KRT6B
Entrez Gene ID 3854
Full Name keratin 6B, type II
Synonyms CK-6B, CK6B, K6B, KRTL1, PC2, PC4
General protein information
Preferred Names
keratin, type II cytoskeletal 6B
Names
keratin, type II cytoskeletal 6B
keratin-6B
cytokeratin 6B
cytokeratin-6B
type-II keratin Kb10
keratin, epidermal, type II, K6B
keratin-like 1 (a type II keratin sequence)
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

12

12q13.13

Summary The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin (KRT6) have been identified; the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. Mutations in these genes have been associated with pachyonychia congenita. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

148042

Disorder Html: Pachyonychia congenita, Jackson-Lawler type, 167210 (3)
CloneID RefSeq Accession Definition **Vector *Turnaround time Price
OHu17785 NM_005555 Homo sapiens keratin 6B, type II (KRT6B), mRNA. pcDNA3.1-C-(k)DYK In stock 5-7 Starting from $99.00

*Business Day
**You may select a custom vector to replace pcDNA3.1-C-(k)DYK after clone is added to cart.



CloneID OHu17785D
Sequence Information ORF Nucleotide Sequence (Length: 1695bp)
Protein sequence
SNP
Vector pcDNA3.1-C-(k)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1-C-(k)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product keratin, type II cytoskeletal 6B
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff in collaboration with Michael Rogers. The reference sequence was derived from BC034535.1 and BG679927.1. This sequence is a reference standard in the RefSeqGene project. On Dec 20, 2006 this sequence version replaced gi:17505187. Summary: The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin (KRT6) have been identified; the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. Mutations in these genes have been associated with pachyonychia congenita. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC034535.1, L42612.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2147975, SAMEA2156670 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
ATGGCCAGCA CATCCACCAC CATCAGGAGC CACAGCAGCA GCCGCCGGGG TTTCAGTGCC 
AACTCAGCCA GGCTCCCTGG GGTCAGCCGC TCTGGCTTCA GCAGCATCTC CGTGTCCCGC
TCCAGGGGCA GTGGTGGCCT GGGTGGCGCA TGTGGAGGAG CTGGCTTTGG CAGCCGCAGT
CTGTATGGCC TGGGGGGCTC CAAGAGGATC TCCATTGGAG GGGGCAGCTG TGCCATCAGT
GGCGGCTATG GCAGCAGAGC CGGAGGCAGC TATGGCTTTG GTGGCGCCGG GAGTGGATTT
GGTTTCGGTG GTGGAGCCGG CATTGGCTTT GGTCTGGGTG GTGGAGCCGG CCTTGCTGGT
GGCTTTGGGG GCCCTGGCTT CCCTGTGTGC CCCCCTGGAG GCATCCAAGA GGTCACTGTC
AACCAGAGTC TCCTGACTCC CCTCAACCTG CAAATTGACC CCGCCATCCA GCGGGTGCGG
GCCGAGGAGC GTGAGCAGAT CAAGACCCTC AACAACAAGT TTGCCTCCTT CATCGACAAG
GTGCGGTTCC TAGAGCAGCA GAACAAGGTT CTGGACACCA AGTGGACCCT GCTGCAGGAG
CAGGGCACCA AGACTGTGAG GCAGAACCTG GAGCCGTTGT TCGAGCAGTA CATCAACAAC
CTCAGGAGGC AGCTGGACAA CATCGTGGGG GAACGGGGTC GTCTGGACTC GGAGCTGAGA
AACATGCAGG ACCTGGTGGA GGACCTCAAG AACAAATATG AGGATGAAAT CAACAAGCGC
ACAGCAGCAG AGAATGAATT TGTGACTCTG AAGAAGGATG TGGATGCTGC CTACATGAAC
AAGGTTGAAC TGCAAGCCAA GGCAGACACT CTTACAGATG AGATCAACTT CCTGAGAGCC
TTGTATGATG CAGAGCTGTC CCAGATGCAG ACCCACATCT CAGACACATC CGTGGTGCTA
TCCATGGACA ACAACCGCAA CCTGGACCTG GACAGCATCA TCGCTGAGGT CAAGGCCCAA
TATGAGGAGA TTGCTCAGAG GAGCAGGGCT GAGGCTGAGT CCTGGTACCA GACAAAGTAC
GAGGAGCTGC AGATCACAGC AGGCAGACAT GGGGACGACC TGCGCAACAC CAAGCAGGAG
ATTGCTGAGA TCAACCGCAT GATCCAGAGG CTGAGATCTG AGATCGACCA CGTCAAGAAG
CAGTGTGCCA ACCTACAGGC CGCCATTGCT GATGCTGAGC AGCGTGGGGA GATGGCCCTC
AAGGATGCTA AGAACAAGCT GGAAGGGCTG GAGGATGCCC TGCAGAAGGC CAAGCAGGAC
CTGGCCCGGC TGCTGAAGGA GTACCAGGAG CTGATGAACG TCAAGCTGGC CCTGGATGTG
GAGATCGCCA CCTACCGCAA GCTGCTGGAG GGCGAGGAGT GCAGGCTGAA TGGCGAAGGC
GTTGGACAAG TCAACATCTC TGTAGTGCAG TCCACCGTCT CCAGTGGCTA TGGCGGTGCC
AGCGGTGTCG GCAGTGGCTT AGGCCTGGGT GGAGGAAGCA GCTACTCCTA TGGCAGTGGT
CTTGGCGTTG GAGGCGGCTT TAGTTCCAGC AGCGGCAGAG CCACTGGGGG TGGCCTCAGC
TCTGTTGGAG GCGGCAGTTC CACCATCAAG TACACCACCA CCTCCTCCTC CAGCAGGAAG
AGCTACAAGC ACTGA
The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.
RefSeqNP_005546.2
CDS49..1743
Misc Feature(1)25..27(+)
Misc Feature(2)52..534(+)
Misc Feature(3)52..54(+)
Misc Feature(4)226..228(+)
Misc Feature(5)532..1473(+)
Misc Feature(6)535..1464(+)
Misc Feature(7)535..642(+)
Misc Feature(8)643..699(+)
Misc Feature(9)700..975(+)
Misc Feature(10)976..1047(+)
Misc Feature(11)1048..1464(+)
Misc Feature(12)1156..>1491(+)
Misc Feature(13)1288..1290(+)
Misc Feature(14)1465..1740(+)
Exon (1)1..588
Gene:KRT6B
Gene Synonym:
Exon (2)589..803
Gene:KRT6B
Gene Synonym:
Exon (3)804..864
Gene:KRT6B
Gene Synonym:
Exon (4)865..960
Gene:KRT6B
Gene Synonym:
Exon (5)961..1125
Gene:KRT6B
Gene Synonym:
Exon (6)1126..1251
Gene:KRT6B
Gene Synonym:
Exon (7)1252..1472
Gene:KRT6B
Gene Synonym:
Exon (8)1473..1507
Gene:KRT6B
Gene Synonym:
Exon (9)1508..2282
Gene:KRT6B
Gene Synonym:
Translation
Position Chain Variation Link
2 2 g, t dbSNP:769496480
14 14 a, t dbSNP:759891347
15 15 a, c dbSNP:776986034
20 20 g, t dbSNP:771284264
21 21 a, c dbSNP:371417078
25 25 g, t dbSNP:566522745
26 26 a, c dbSNP:426977
28 28 g, t dbSNP:772167585
29 29 c, t dbSNP:748294034
30 30 c, t dbSNP:451006
32 32 c, t dbSNP:755251621
34 34 c, t dbSNP:750180799
44 44 a, c, g dbSNP:757105509
49 49 a, g dbSNP:367617134
50 50 c, t dbSNP:527241258
59 59 c, t dbSNP:762438614
64 64 a, g dbSNP:752271878
65 65 a, c dbSNP:764803667
68 68 c, t dbSNP:759200378
71 71 a, c, t dbSNP:200240023
78 78 c, g dbSNP:561690979
90 90 -, agc dbSNP:746750535
91 91 a, c, t dbSNP:772519522
92 92 a, g, t dbSNP:779144610
94 94 c, t dbSNP:768946287
95 95 a, g dbSNP:749556525
96 96 a, g dbSNP:780182784
98 98 g, t dbSNP:757055827
100 100 a, t dbSNP:751372178
107 107 c, t dbSNP:374567840
109 109 a, g dbSNP:201864717
110 110 a, g dbSNP:428894
120 120 c, g, t dbSNP:764749883
121 121 c, t dbSNP:759087767
123 123 c, t dbSNP:372179759
126 126 a, t dbSNP:766003979
130 130 a, g dbSNP:761093716
135 135 a, c dbSNP:773449867
136 136 c, t dbSNP:368410373
137 137 a, g, t dbSNP:374275504
139 139 c, t dbSNP:768829710
140 140 a, c dbSNP:749431471
148 148 a, g dbSNP:548276151
153 153 a, c dbSNP:769979285
154 154 a, g dbSNP:404970
165 165 c, t dbSNP:777443894
166 166 c, t dbSNP:758283387
167 167 a, g dbSNP:139304263
171 171 c, t dbSNP:778871189
174 174 a, g dbSNP:150268236
175 175 a, c, g dbSNP:765986155
176 176 a, g dbSNP:755733133
184 184 a, g dbSNP:373935299
195 195 c, t dbSNP:445185
196 196 a, g dbSNP:762312695
197 197 a, c dbSNP:774980327
204 204 a, g dbSNP:764758877
205 205 a, g dbSNP:201156749
209 209 c, t dbSNP:775438004
214 214 c, t dbSNP:770002769
223 223 a, c, t dbSNP:370887221
224 224 a, g dbSNP:771831330
228 228 c, t dbSNP:747994676
229 229 c, t dbSNP:778816046
231 231 a, g dbSNP:368087535
236 236 a, g dbSNP:748772716
242 242 a, g dbSNP:779449161
245 245 a, g, t dbSNP:562648897
246 246 a, c dbSNP:141114189
256 256 a, c dbSNP:546022490
258 258 a, c dbSNP:752039509
262 262 a, g dbSNP:764630392
263 263 c, t dbSNP:374536069
281 281 a, c dbSNP:752774038
285 285 c, t dbSNP:765264911
287 287 a, g dbSNP:560354778
290 290 c, g dbSNP:776820315
291 291 c, t dbSNP:771207924
292 292 a, g dbSNP:761528539
299 299 a, g dbSNP:774143030
309 309 c, t dbSNP:768587301
310 310 a, g dbSNP:61914500
315 315 c, t dbSNP:540159600
333 333 c, t dbSNP:780076492
334 334 a, g dbSNP:769168555
337 337 a, g dbSNP:144860693
341 341 a, g dbSNP:780990421
349 349 a, g dbSNP:756978054
355 355 a, c, g dbSNP:778306714
363 363 a, g dbSNP:758899246
366 366 c, t dbSNP:753114842
367 367 a, g dbSNP:765830157
380 380 a, g dbSNP:61914499
389 389 a, g dbSNP:753917253
391 391 a, g dbSNP:766529656
392 392 a, g dbSNP:574747070
398 398 a, g dbSNP:774088015
411 411 c, t dbSNP:554558110
421 421 c, t dbSNP:202222264
425 425 a, g dbSNP:146454705
428 428 g, t dbSNP:769839426
430 430 c, g, t dbSNP:780863866
432 432 c, t dbSNP:374587684
433 433 g, t dbSNP:369674246
435 435 a, g dbSNP:777522365
439 439 c, t dbSNP:758676534
440 440 c, g dbSNP:753172591
441 441 a, c dbSNP:779219726
442 442 a, c dbSNP:377681409
443 443 -, c dbSNP:772129177
449 449 a, g dbSNP:753862175
456 456 -, a dbSNP:745376618
461 461 a, t dbSNP:766474462
464 464 a, c dbSNP:756223113
465 465 c, t dbSNP:200768134
469 469 a, g dbSNP:767841535
470 470 a, g dbSNP:762655433
471 471 c, g dbSNP:775362040
472 472 c, t dbSNP:765029954
473 473 a, g dbSNP:759570731
475 475 -, ag dbSNP:778507254
475 475 a, c dbSNP:776244062
476 476 a, g dbSNP:28538343
480 480 c, g dbSNP:746567208
481 481 c, t dbSNP:772734398
483 483 g, t dbSNP:771760662
487 487 c, t dbSNP:748401975
490 490 c, t dbSNP:779355995
497 497 g, t dbSNP:755434590
498 498 a, g, t dbSNP:780585163
503 503 c, t dbSNP:756176376
504 504 c, t dbSNP:750585194
507 507 c, g dbSNP:767573535
510 510 c, t dbSNP:145409385
511 511 a, c, g, t dbSNP:1701772
513 513 c, t dbSNP:776688562
515 515 a, t dbSNP:766490253
517 517 c, t dbSNP:760194733
518 518 -, a dbSNP:756988481
518 518 a, c dbSNP:772792323
520 520 a, c, g, t dbSNP:537928073
521 521 a, g, t dbSNP:749707973
523 523 c, g dbSNP:780538097
527 527 a, g dbSNP:756620061
529 529 a, g dbSNP:745882173
531 531 a, c, t dbSNP:757382249
532 532 a, g dbSNP:751774991
538 538 a, c, t dbSNP:754808789
539 539 a, g dbSNP:140336962
540 540 a, t dbSNP:145590668
543 543 a, g dbSNP:199847801
543 543 -, g dbSNP:748926371
555 555 c, g dbSNP:749859479
561 561 c, t dbSNP:767019100
564 564 -, caa dbSNP:267607472
567 567 a, g dbSNP:149739313
571 571 a, g dbSNP:761274146
582 582 c, t dbSNP:774038128
585 585 c, t dbSNP:768367699
592 592 c, t dbSNP:773446875
593 593 a, g dbSNP:71453293
596 596 c, t dbSNP:748349199
598 598 c, t dbSNP:779322800
599 599 c, t dbSNP:755921080
601 601 a, c, g dbSNP:372358048
605 605 a, g dbSNP:151027332
606 606 g, t dbSNP:553527200
607 607 c, t dbSNP:757158283
615 615 c, g dbSNP:150221772
624 624 a, c, t dbSNP:757944028
626 626 c, t dbSNP:752324819
627 627 a, c dbSNP:764857770
635 635 c, t dbSNP:139925091
636 636 a, c dbSNP:776872109
638 638 c, t dbSNP:766857971
643 643 a, c, g dbSNP:773894817
646 646 g, t dbSNP:368610959
657 657 c, t dbSNP:147485252
659 659 -, a dbSNP:755417296
665 665 c, t dbSNP:774708160
668 668 c, g dbSNP:375136721
672 672 c, g dbSNP:745621221
674 674 a, t dbSNP:780874416
679 679 a, c, g dbSNP:746921672
683 683 c, t dbSNP:11170126
684 684 a, g dbSNP:143150216
690 690 c, t dbSNP:752273636
691 691 a, g dbSNP:201956073
692 692 a, c dbSNP:754608090
695 695 a, g dbSNP:754188714
699 699 c, t dbSNP:766622037
711 711 c, t dbSNP:761170216
726 726 c, g dbSNP:368023519
728 728 a, g dbSNP:3194286
728 728 a, g, t dbSNP:652423
729 729 c, g dbSNP:774305985
732 732 a, c, t dbSNP:370270393
732 732 -, c dbSNP:751859924
733 733 a, g dbSNP:778566012
735 735 a, c, g dbSNP:71453292
739 739 a, g dbSNP:746866169
742 742 a, c, g dbSNP:772003182
743 743 a, g dbSNP:747606364
746 746 a, g dbSNP:538724780
747 747 c, t dbSNP:28542657
748 748 c, t dbSNP:753409446
749 749 a, g, t dbSNP:756538750
750 750 c, t dbSNP:28414881
752 752 c, g, t dbSNP:529792162
753 753 a, g dbSNP:751621723
758 758 c, t dbSNP:764052533
759 759 a, g dbSNP:149632179
760 760 c, g dbSNP:775562449
771 771 c, t dbSNP:550429613
776 776 a, g dbSNP:760396362
777 777 a, g dbSNP:773006521
780 780 a, c dbSNP:530749595
783 783 a, g dbSNP:771955772
789 789 c, g dbSNP:748003288
792 792 c, t dbSNP:368725862
793 793 c, t dbSNP:138341104
794 794 a, t dbSNP:748891526
804 804 a, t dbSNP:374135700
810 810 a, g dbSNP:752673201
811 811 g, t dbSNP:765268457
813 813 c, t dbSNP:755098928
826 826 c, t dbSNP:538217383
827 827 a, g dbSNP:377313061
844 844 a, g dbSNP:150075508
848 848 c, t dbSNP:566467226
856 856 a, c, t dbSNP:762976356
857 857 c, t dbSNP:775611997
858 858 a, g dbSNP:552622526
867 867 c, t dbSNP:150034493
868 868 a, g dbSNP:780212659
871 871 g, t dbSNP:756186078
875 875 a, c dbSNP:137905665
876 876 g, t dbSNP:145344532
880 880 -, t dbSNP:533997961
883 883 a, t dbSNP:140303040
886 886 a, c dbSNP:371788244
889 889 a, c dbSNP:151191247
892 892 a, c, g, t dbSNP:753361235
894 894 a, t dbSNP:765889169
899 899 a, t dbSNP:368064736
900 900 a, g dbSNP:772910057
905 905 a, c dbSNP:771623502
911 911 a, c dbSNP:374881736
913 913 a, g dbSNP:200532105
915 915 a, c, t dbSNP:572718504
921 921 c, t dbSNP:382894
927 927 c, t dbSNP:749763025
931 931 a, c dbSNP:371478761
935 935 a, g dbSNP:367794230
936 936 c, t dbSNP:764558869
949 949 c, t dbSNP:746002443
951 951 c, g dbSNP:781409851
955 955 a, g dbSNP:757570546
964 964 a, c dbSNP:536802368
966 966 g, t dbSNP:571421123
971 971 a, c dbSNP:756807390
974 974 g, t dbSNP:551355854
982 982 c, t dbSNP:142625176
986 986 a, t dbSNP:763310605
994 994 a, g dbSNP:370461879
997 997 c, g, t dbSNP:566062730
999 999 c, g, t dbSNP:377079859
1000 1000 a, g dbSNP:771115384
1008 1008 a, g dbSNP:747149723
1010 1010 c, g dbSNP:773498316
1012 1012 a, c, g dbSNP:145091946
1013 1013 a, t dbSNP:779744349
1024 1024 c, t dbSNP:190319305
1025 1025 a, g, t dbSNP:781162204
1029 1029 c, t dbSNP:756758177
1033 1033 a, g dbSNP:751075044
1037 1037 c, t dbSNP:145327282
1040 1040 a, g dbSNP:758010117
1041 1041 c, g dbSNP:753070394
1045 1045 a, g dbSNP:765492618
1050 1050 c, t dbSNP:759996259
1051 1051 a, g, t dbSNP:369853484
1056 1056 a, g dbSNP:752580660
1059 1059 c, g dbSNP:760775348
1071 1071 c, t dbSNP:367709654
1072 1072 a, g dbSNP:772378946
1075 1075 a, g dbSNP:761909527
1078 1078 a, g dbSNP:774682488
1080 1080 g, t dbSNP:769460857
1081 1081 g, t dbSNP:745743945
1089 1089 a, g dbSNP:781042956
1093 1093 a, c, g dbSNP:11503946
1111 1111 g, t dbSNP:777300878
1112 1112 g, t dbSNP:757970006
1119 1119 a, g dbSNP:373549008
1120 1120 a, g dbSNP:778688221
1122 1122 a, c dbSNP:755228431
1127 1127 a, c dbSNP:760524758
1128 1128 c, t dbSNP:773022037
1133 1133 a, c dbSNP:772057116
1141 1141 a, g dbSNP:437014
1148 1148 c, t dbSNP:773938726
1151 1151 a, g dbSNP:768087354
1157 1157 a, g dbSNP:748925772
1164 1164 c, t dbSNP:779910657
1165 1165 a, g dbSNP:756540663
1166 1166 a, g, t dbSNP:781494966
1169 1169 c, t dbSNP:757806566
1171 1171 c, t dbSNP:751554113
1172 1172 a, g dbSNP:764203649
1180 1180 a, c dbSNP:758526690
1182 1182 a, g dbSNP:752907331
1192 1192 g, t dbSNP:765512406
1203 1203 c, g dbSNP:760398334
1204 1204 a, c, t dbSNP:767313923
1205 1205 a, g dbSNP:368362440
1211 1211 c, t dbSNP:774203775
1233 1233 c, t dbSNP:768268060
1234 1234 a, g dbSNP:138988810
1239 1239 a, c, t dbSNP:146904435
1242 1242 a, c dbSNP:746172336
1246 1246 a, g dbSNP:139792514
1253 1253 a, g dbSNP:754076285
1260 1260 -, aac dbSNP:774025074
1261 1261 c, t dbSNP:780207885
1264 1264 c, t dbSNP:757008227
1265 1265 a, g dbSNP:751323410
1267 1267 a, g dbSNP:377408881
1269 1269 c, t dbSNP:388626
1270 1270 a, g dbSNP:141947025
1271 1271 c, t dbSNP:764818442
1272 1272 c, t dbSNP:759029794
1274 1274 c, t dbSNP:776346440
1276 1276 a, g dbSNP:770497003
1283 1283 c, t dbSNP:761046409
1291 1291 c, t dbSNP:556860047
1292 1292 a, g, t dbSNP:200778388
1297 1297 g, t dbSNP:747142811
1304 1304 c, t dbSNP:774892962
1305 1305 a, c dbSNP:202113612
1308 1308 c, g, t dbSNP:780264075
1317 1317 c, t dbSNP:756312531
1322 1322 a, g dbSNP:190534022
1334 1334 g, t dbSNP:552603264
1339 1339 a, g dbSNP:758318631
1349 1349 c, t dbSNP:752669022
1351 1351 a, c dbSNP:765335449
1354 1354 a, t dbSNP:754446188
1356 1356 a, g dbSNP:142940927
1361 1361 a, g dbSNP:146391553
1362 1362 a, g dbSNP:142297644
1364 1364 a, g dbSNP:772897031
1369 1369 c, g dbSNP:137872925
1374 1374 c, t dbSNP:762230367
1375 1375 c, g, t dbSNP:199727604
1376 1376 a, g dbSNP:749339703
1377 1377 a, c, g dbSNP:370595590
1379 1379 a, t dbSNP:769957795
1389 1389 c, g dbSNP:746067350
1396 1396 c, g dbSNP:781622834
1399 1399 c, g dbSNP:758267248
1403 1403 c, t dbSNP:368909076
1407 1407 c, t dbSNP:145280284
1408 1408 a, g dbSNP:141597595
1419 1419 a, c dbSNP:753850271
1422 1422 a, g dbSNP:765779732
1425 1425 c, t dbSNP:755676997
1429 1429 a, g dbSNP:267607473
1431 1431 a, g dbSNP:750068055
1434 1434 c, t dbSNP:767159401
1435 1435 a, g, t dbSNP:772103229
1436 1436 c, t dbSNP:764620689
1440 1440 a, c dbSNP:763339267
1444 1444 c, t dbSNP:138479175
1445 1445 a, g, t dbSNP:759757944
1459 1459 g, t dbSNP:150128167
1461 1461 c, t dbSNP:747596381
1462 1462 a, g dbSNP:60627726
1464 1464 a, g dbSNP:376510657
1473 1473 g, t dbSNP:758625476
1482 1482 c, t dbSNP:753121763
1483 1483 a, g dbSNP:369418982
1488 1488 c, t dbSNP:373899186
1489 1489 a, g dbSNP:140834481
1495 1495 a, c dbSNP:754440839
1504 1504 a, g dbSNP:370394338
1512 1512 a, g dbSNP:762600737
1515 1515 a, g dbSNP:148044538
1517 1517 a, g dbSNP:755323118
1518 1518 g, t dbSNP:749680153
1524 1524 c, t dbSNP:201073484
1525 1525 a, g dbSNP:147008947
1532 1532 a, g dbSNP:750932643
1538 1538 a, g dbSNP:61746354
1539 1539 g, t dbSNP:757339399
1542 1542 a, c, t dbSNP:147867894
1543 1543 a, g dbSNP:61746355
1551 1551 c, t dbSNP:753657782
1552 1552 a, c, g dbSNP:149152547
1557 1557 c, t dbSNP:145254155
1558 1558 a, g dbSNP:150021015
1560 1560 c, t dbSNP:546061164
1570 1570 c, g dbSNP:774086396
1571 1571 a, g dbSNP:139358472
1574 1574 c, t dbSNP:749628792
1585 1585 a, g dbSNP:780534493
1586 1586 a, g dbSNP:770104486
1590 1590 c, t dbSNP:146373607
1596 1596 c, t dbSNP:61749468
1597 1597 c, t dbSNP:200055232
1599 1599 a, c, t dbSNP:373264955
1612 1612 a, g dbSNP:542447561
1613 1613 a, g dbSNP:777924533
1614 1614 c, t dbSNP:140188440
1615 1615 a, g dbSNP:146173634
1619 1619 a, g dbSNP:141150690
1623 1623 c, t dbSNP:766177343
1624 1624 a, g dbSNP:376429278
1629 1629 c, t dbSNP:750303987
1634 1634 c, t dbSNP:767365375
1641 1641 a, c, t dbSNP:148209422
1642 1642 a, g dbSNP:143946299
1645 1645 a, g dbSNP:762671974
1648 1648 -, gcc dbSNP:777542750
1651 1651 -, gaac dbSNP:769329834
1652 1652 -, ct dbSNP:747408258
1652 1652 c, t dbSNP:554596962
1654 1654 g, t dbSNP:770190928
1655 1655 a, g dbSNP:746223280
1656 1656 a, g dbSNP:781682935
1657 1657 a, g dbSNP:149495966
1658 1658 -, a dbSNP:780343812
1658 1658 a, g dbSNP:747053952
1663 1663 c, g dbSNP:777803130
1673 1673 c, t dbSNP:138021918
1680 1680 c, t dbSNP:575779389
1681 1681 a, g dbSNP:146988096
1683 1683 a, c dbSNP:755876853
1685 1685 a, g dbSNP:145923896
1688 1688 c, g, t dbSNP:141409814
1692 1692 c, t dbSNP:757227143
1693 1693 a, g dbSNP:751594384
1695 1695 c, g dbSNP:763683330
1701 1701 a, c dbSNP:762618910
1703 1703 c, g dbSNP:775142460
1709 1709 a, c dbSNP:539318306
1713 1713 c, t dbSNP:138933209
1715 1715 c, t dbSNP:200620417
1721 1721 a, g, t dbSNP:771328301
1725 1725 a, g dbSNP:747495865
1727 1727 a, g dbSNP:371758517
1738 1738 a, c dbSNP:772139797
1740 1740 c, g dbSNP:748185532
1743 1743 a, g dbSNP:779143449
1751 1751 a, c dbSNP:567093999
1752 1752 c, t dbSNP:749563252
1753 1753 a, g, t dbSNP:200690379
1755 1755 -, c dbSNP:758927616
1757 1757 c, g dbSNP:751538324
1759 1759 c, t dbSNP:764131660
1760 1760 c, t dbSNP:757924059
1769 1769 a, g dbSNP:752172491
1771 1771 a, c, g dbSNP:549184060
1780 1780 a, g dbSNP:759082678
1782 1782 c, t dbSNP:776365127
1812 1812 a, g dbSNP:760989336
1853 1853 c, g dbSNP:75893729
1859 1859 c, g dbSNP:568087038
1866 1866 a, g dbSNP:548270201
1930 1930 a, c dbSNP:535888045
1955 1955 c, t dbSNP:544756853
1968 1968 a, t dbSNP:569009342
1970 1970 -, g dbSNP:553864968
1975 1975 c, t dbSNP:552132387
1976 1976 a, g dbSNP:772264432
1994 1994 g, t dbSNP:532425818
2061 2061 c, g dbSNP:748270391
2078 2078 c, t dbSNP:559974200
2093 2093 c, t dbSNP:540139576
2108 2108 a, g dbSNP:530008221
2160 2160 c, t dbSNP:560980582
2162 2162 c, t dbSNP:116436520
2166 2166 a, c dbSNP:73308613
2169 2169 c, t dbSNP:778963143
2172 2172 c, t dbSNP:561715124
2189 2189 c, t dbSNP:745722883
2195 2195 a, t dbSNP:545233358
2231 2231 c, g dbSNP:781067320
2270 2270 c, t dbSNP:187031962
2277 2277 c, t dbSNP:553678436

Target ORF information:

RefSeq Version NM_005555
Organism Homo sapiens (human)
Definition Homo sapiens keratin 6B, type II (KRT6B), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1-C-(k)DYK
NM_005555

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
ATGGCCAGCA CATCCACCAC CATCAGGAGC CACAGCAGCA GCCGCCGGGG TTTCAGTGCC 
AACTCAGCCA GGCTCCCTGG GGTCAGCCGC TCTGGCTTCA GCAGCATCTC CGTGTCCCGC
TCCAGGGGCA GTGGTGGCCT GGGTGGCGCA TGTGGAGGAG CTGGCTTTGG CAGCCGCAGT
CTGTATGGCC TGGGGGGCTC CAAGAGGATC TCCATTGGAG GGGGCAGCTG TGCCATCAGT
GGCGGCTATG GCAGCAGAGC CGGAGGCAGC TATGGCTTTG GTGGCGCCGG GAGTGGATTT
GGTTTCGGTG GTGGAGCCGG CATTGGCTTT GGTCTGGGTG GTGGAGCCGG CCTTGCTGGT
GGCTTTGGGG GCCCTGGCTT CCCTGTGTGC CCCCCTGGAG GCATCCAAGA GGTCACTGTC
AACCAGAGTC TCCTGACTCC CCTCAACCTG CAAATTGACC CCGCCATCCA GCGGGTGCGG
GCCGAGGAGC GTGAGCAGAT CAAGACCCTC AACAACAAGT TTGCCTCCTT CATCGACAAG
GTGCGGTTCC TAGAGCAGCA GAACAAGGTT CTGGACACCA AGTGGACCCT GCTGCAGGAG
CAGGGCACCA AGACTGTGAG GCAGAACCTG GAGCCGTTGT TCGAGCAGTA CATCAACAAC
CTCAGGAGGC AGCTGGACAA CATCGTGGGG GAACGGGGTC GTCTGGACTC GGAGCTGAGA
AACATGCAGG ACCTGGTGGA GGACCTCAAG AACAAATATG AGGATGAAAT CAACAAGCGC
ACAGCAGCAG AGAATGAATT TGTGACTCTG AAGAAGGATG TGGATGCTGC CTACATGAAC
AAGGTTGAAC TGCAAGCCAA GGCAGACACT CTTACAGATG AGATCAACTT CCTGAGAGCC
TTGTATGATG CAGAGCTGTC CCAGATGCAG ACCCACATCT CAGACACATC CGTGGTGCTA
TCCATGGACA ACAACCGCAA CCTGGACCTG GACAGCATCA TCGCTGAGGT CAAGGCCCAA
TATGAGGAGA TTGCTCAGAG GAGCAGGGCT GAGGCTGAGT CCTGGTACCA GACAAAGTAC
GAGGAGCTGC AGATCACAGC AGGCAGACAT GGGGACGACC TGCGCAACAC CAAGCAGGAG
ATTGCTGAGA TCAACCGCAT GATCCAGAGG CTGAGATCTG AGATCGACCA CGTCAAGAAG
CAGTGTGCCA ACCTACAGGC CGCCATTGCT GATGCTGAGC AGCGTGGGGA GATGGCCCTC
AAGGATGCTA AGAACAAGCT GGAAGGGCTG GAGGATGCCC TGCAGAAGGC CAAGCAGGAC
CTGGCCCGGC TGCTGAAGGA GTACCAGGAG CTGATGAACG TCAAGCTGGC CCTGGATGTG
GAGATCGCCA CCTACCGCAA GCTGCTGGAG GGCGAGGAGT GCAGGCTGAA TGGCGAAGGC
GTTGGACAAG TCAACATCTC TGTAGTGCAG TCCACCGTCT CCAGTGGCTA TGGCGGTGCC
AGCGGTGTCG GCAGTGGCTT AGGCCTGGGT GGAGGAAGCA GCTACTCCTA TGGCAGTGGT
CTTGGCGTTG GAGGCGGCTT TAGTTCCAGC AGCGGCAGAG CCACTGGGGG TGGCCTCAGC
TCTGTTGGAG GCGGCAGTTC CACCATCAAG TACACCACCA CCTCCTCCTC CAGCAGGAAG
AGCTACAAGC ACTGA

The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.