||ORF Nucleotide Sequence (Length: 1422bp)
||pcDNA3.1-C-(k)DYK or customized vector
|Tag on pcDNA3.1-C-(k)DYK
||C terminal DYKDDDDK tags
|ORF Insert Method
||CloneEZ® Seamless cloning technology
||Homo sapiens (human)
||keratin, type I cytoskeletal 16
||REVIEWED REFSEQ: This record has been curated by NCBI staff in
collaboration with Michael Rogers. The reference sequence was
derived from DC394235.1, AK290853.1 and BC039169.1.
This sequence is a reference standard in the RefSeqGene project.
On Dec 20, 2007 this sequence version replaced gi:24430191.
Summary: The protein encoded by this gene is a member of the
keratin gene family. The keratins are intermediate filament
proteins responsible for the structural integrity of epithelial
cells and are subdivided into cytokeratins and hair keratins. Most
of the type I cytokeratins consist of acidic proteins which are
arranged in pairs of heterotypic keratin chains and are clustered
in a region of chromosome 17q12-q21. This keratin has been
coexpressed with keratin 14 in a number of epithelial tissues,
including esophagus, tongue, and hair follicles. Mutations in this
gene are associated with type 1 pachyonychia congenita,
non-epidermolytic palmoplantar keratoderma and unilateral
palmoplantar verrucous nevus. [provided by RefSeq, Jul 2008].
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
Transcript exon combination :: BC039169.1, AF061812.1 [ECO:0000332]
RNAseq introns :: mixed/partial sample support
COMPLETENESS: complete on the 3' end.