||ORF Nucleotide Sequence (Length: 1482bp)
||pcDNA3.1-C-(k)DYK or customized vector
|Tag on pcDNA3.1-C-(k)DYK
||C terminal DYKDDDDK tags
|ORF Insert Method
||CloneEZ® Seamless cloning technology
||Homo sapiens (human)
||keratin, type II cuticular Hb3
||REVIEWED REFSEQ: This record has been curated by NCBI staff in
collaboration with Michael Rogers. The reference sequence was
derived from AC121757.8 and BC069546.1.
This sequence is a reference standard in the RefSeqGene project.
On or before Feb 9, 2014 this sequence version replaced
gi:578796637, gi:410169881, gi:15431322.
Summary: The protein encoded by this gene is a member of the
keratin gene family. As a type II hair keratin, it is a basic
protein which heterodimerizes with type I keratins to form hair and
nails. The type II hair keratins are clustered in a region of
chromosome 12q13 and are grouped into two distinct subfamilies
based on structure similarity. One subfamily, consisting of KRTHB1,
KRTHB3, and KRTHB6, is highly related. The other less-related
subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins
are expressed in the hair follicle; this hair keratin, as well as
KRTHB1 and KRTHB6, is found primarily in the hair cortex. [provided
by RefSeq, Jul 2008].
Sequence Note: This RefSeq record was created from transcript and
genomic sequence data because transcript sequence consistent with
the reference genome assembly was not available for all regions of
the RefSeq transcript. The extent of this transcript is supported
by transcript alignments.
Transcript exon combination :: X99141.1, BC128063.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
COMPLETENESS: complete on the 3' end.