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MAFA v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A [Homo sapiens (human)]

Gene Symbol MAFA
Entrez Gene ID 389692
Full Name v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A
Synonyms RIPE3b1, hMafA
General protein information
Preferred Names
transcription factor MafA
Names
transcription factor MafA
transcription factor RIPE3b1
pancreatic beta-cell-specific transcriptional activator
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

8

8q24.3

Summary MAFA is a transcription factor that binds RIPE3b, a conserved enhancer element that regulates pancreatic beta cell-specific expression of the insulin gene (INS; MIM 176730) (Olbrot et al., 2002 [PubMed 12011435]).[supplied by OMIM, Mar 2008]. lac of sum
Disorder MIM:

610303

Disorder Html:





The following MAFA gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MAFA gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu23130 NM_201589 Homo sapiens v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A (MAFA), mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $319

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu23130
Accession Version NM_201589.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1062bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector Document: User manual_GenEZ ORF Clone Products.pdf (pdf)
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags Document: MSDS_GenEZ ORF Clone Products.pdf (pdf)
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 10-MAY-2014
Organism Homo sapiens (human)
Product transcription factor MafA
Comment VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC105118.23. On Dec 3, 2010 this sequence version replaced gi:71274110. Summary: MAFA is a transcription factor that binds RIPE3b, a conserved enhancer element that regulates pancreatic beta cell-specific expression of the insulin gene (INS; MIM 176730) (Olbrot et al., 2002 [PubMed 12011435]).[supplied by OMIM, Mar 2008]. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGGCCGCGG AGCTGGCGAT GGGCGCCGAG CTGCCCAGCA GCCCGCTGGC CATCGAGTAC 
GTCAACGACT TCGACCTGAT GAAGTTCGAG GTGAAGAAGG AGCCTCCCGA GGCCGAGCGC
TTCTGCCACC GCCTGCCGCC AGGCTCGCTG TCCTCGACGC CGCTCAGCAC GCCCTGCTCC
TCCGTGCCCT CCTCGCCCAG CTTCTGCGCG CCCAGCCCGG GCACCGGCGG CGGCGGCGGC
GCGGGGGGCG GCGGCGGCTC GTCTCAGGCC GGGGGCGCCC CCGGGCCGCC GAGCGGGGGC
CCCGGCGCCG TCGGGGGCAC CTCGGGGAAG CCGGCGCTGG AGGATCTGTA CTGGATGAGC
GGCTACCAGC ATCACCTCAA CCCCGAGGCG CTCAACCTGA CGCCCGAGGA CGCGGTGGAG
GCGCTCATCG GCAGCGGCCA CCACGGCGCG CACCACGGCG CGCACCACCC GGCGGCCGCC
GCAGCCTACG AGGCTTTCCG CGGCCCGGGC TTCGCGGGCG GCGGCGGAGC GGACGACATG
GGCGCCGGCC ACCACCACGG CGCGCACCAC GCCGCCCACC ATCACCACGC CGCCCACCAC
CACCACCACC ACCACCACCA CCATGGCGGC GCGGGACACG GCGGTGGCGC GGGCCACCAC
GTGCGCCTGG AGGAGCGCTT CTCCGACGAC CAGCTGGTGT CCATGTCGGT GCGCGAGCTG
AACCGGCAGC TCCGCGGCTT CAGCAAGGAG GAGGTCATCC GGCTCAAGCA GAAGCGGCGC
ACGCTCAAGA ACCGCGGCTA CGCGCAGTCC TGCCGCTTCA AGCGGGTGCA GCAGCGGCAC
ATTCTGGAGA GCGAGAAGTG CCAACTCCAG AGCCAGGTGG AGCAGCTGAA GCTGGAGGTG
GGGCGCCTGG CCAAAGAGCG GGACCTGTAC AAGGAGAAAT ACGAGAAGCT GGCGGGCCGG
GGCGGCCCCG GGAGCGCGGG CGGGGCCGGT TTCCCGCGGG AGCCTTCGCC GCCGCAGGCC
GGTCCCGGCG GGGCCAAGGG CACGGCCGAC TTCTTCCTGT AG
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_963883.2
CDS27..1088
Misc Feature(1)66..68(+)
Misc Feature(2)66..68(+)
Misc Feature(3)66..68(+)
Misc Feature(4)171..173(+)
Misc Feature(5)183..185(+)
Misc Feature(6)195..197(+)
Misc Feature(7)207..209(+)
Misc Feature(8)219..221(+)
Misc Feature(9)219..221(+)
Misc Feature(10)357..461(+)
Misc Feature(11)771..977(+)
Misc Feature(12)771..977(+)
Misc Feature(13)786..863(+)
Misc Feature(14)792..851(+)
Misc Feature(15)804..848(+)
Misc Feature(16)849..968(+)
Misc Feature(17)870..935(+)
Exon (1)1..2373
Gene:MAFA
Gene Synonym:
Translation
Position Chain Variation Link
18 18 c, t dbSNP:747251291
19 19 a, c dbSNP:777851207
20 20 a, c dbSNP:772143913
35 35 a, g dbSNP:376376038
43 43 c, t dbSNP:779370771
58 58 c, t dbSNP:201493864
66 66 a, c dbSNP:754227415
67 67 a, c, g dbSNP:755736896
68 68 c, t dbSNP:750051600
91 91 a, g dbSNP:767100342
101 101 c, t dbSNP:761426279
105 105 a, g dbSNP:751160541
110 110 c, g dbSNP:562695240
130 130 c, t dbSNP:762864133
131 131 c, t dbSNP:544512339
135 135 c, g dbSNP:529585367
144 144 c, g dbSNP:139422405
157 157 a, g dbSNP:371867015
163 163 a, c dbSNP:562242155
164 164 a, g dbSNP:772330144
218 218 a, c dbSNP:748197069
234 234 a, g dbSNP:368146503
244 244 c, t dbSNP:774483749
265 265 -, gcg dbSNP:757003114
269 269 a, g dbSNP:769141003
319 319 a, g dbSNP:540650393
320 320 c, t dbSNP:780402901
325 325 a, g dbSNP:756470274
340 340 a, g, t dbSNP:780966097
372 372 c, t dbSNP:757006759
401 401 c, t dbSNP:573140928
402 402 c, t dbSNP:763752855
405 405 a, t dbSNP:758296852
410 410 c, g dbSNP:752581189
411 411 c, g dbSNP:765040852
416 416 g, t dbSNP:759230371
419 419 c, t dbSNP:75183115
424 424 g, t dbSNP:767723387
441 441 a, g dbSNP:762082415
446 446 a, g dbSNP:373992315
452 452 c, g dbSNP:768626648
453 453 a, t dbSNP:749766765
454 454 a, t dbSNP:775887773
455 455 c, t dbSNP:770377222
477 477 c, t dbSNP:149797559
499 499 a, c dbSNP:781731297
547 547 a, g dbSNP:756955386
583 583 a, c dbSNP:746671307
585 585 g, t dbSNP:777351995
589 589 c, t dbSNP:757877395
590 590 a, g dbSNP:752301689
593 593 c, t dbSNP:765054613
594 594 c, g dbSNP:755010855
598 598 a, c dbSNP:753619572
608 608 c, t dbSNP:1872900
620 620 -, cca dbSNP:552049497
621 621 c, g dbSNP:201366562
622 622 a, c dbSNP:200369669
632 632 -, ccaccaccaccaccacca dbSNP:760978293
635 635 -, ccaccaccaccacca dbSNP:773437878
638 638 -, ccaccaccacca dbSNP:766702155
641 641 -, ccaccacca dbSNP:772234449
643 643 a, t dbSNP:761959761
644 644 -, ccacca dbSNP:758856279
644 644 -, cca dbSNP:765697134
644 644 c, t dbSNP:751813631
647 647 -, cca dbSNP:141816879
647 647 c, g dbSNP:764189248
657 657 a, g dbSNP:538034673
679 679 a, g dbSNP:762915364
698 698 a, g dbSNP:775676368
702 702 c, t dbSNP:770194525
716 716 c, g dbSNP:533513408
719 719 g, t dbSNP:777076988
734 734 a, g dbSNP:374635558
751 751 a, g dbSNP:746619935
752 752 a, g dbSNP:564401181
755 755 g, t dbSNP:771797520
758 758 c, t dbSNP:747608736
761 761 a, c dbSNP:778545207
768 768 a, g dbSNP:754816548
773 773 c, g dbSNP:753781845
783 783 a, c dbSNP:371413333
785 785 c, g, t dbSNP:750272175
788 788 a, g dbSNP:764187727
793 793 a, g dbSNP:763299274
794 794 c, g dbSNP:533798229
803 803 a, g dbSNP:765369888
804 804 c, t dbSNP:760051830
819 819 a, c dbSNP:777308147
822 822 c, g, t dbSNP:761090493
823 823 a, g dbSNP:773693521
833 833 g, t dbSNP:376902337
834 834 a, t dbSNP:747852573
841 841 g, t dbSNP:778217634
848 848 a, g dbSNP:78739463
850 850 a, g dbSNP:375787953
854 854 a, g dbSNP:779940817
861 861 c, t dbSNP:756089406
863 863 a, g dbSNP:750218912
867 867 a, g dbSNP:781101982
870 870 c, g dbSNP:758494979
871 871 a, t dbSNP:752970319
873 873 c, g dbSNP:370944985
877 877 a, g dbSNP:765193247
878 878 c, g dbSNP:377604049
879 879 a, g dbSNP:551063688
886 886 a, g dbSNP:367978241
896 896 a, c, g dbSNP:773390216
903 903 a, g dbSNP:767927182
906 906 g, t dbSNP:761329264
909 909 c, g dbSNP:774072432
919 919 c, t dbSNP:768343109
920 920 a, g dbSNP:748761183
923 923 a, g dbSNP:568603836
927 927 a, g dbSNP:769710001
929 929 g, t dbSNP:745833807
931 931 a, g dbSNP:780786479
935 935 c, g dbSNP:373860335
936 936 a, g dbSNP:757108779
950 950 a, c, g dbSNP:779255211
953 953 a, g dbSNP:755318727
954 954 c, t dbSNP:200756485
956 956 c, g dbSNP:199855391
959 959 a, g dbSNP:766578339
972 972 a, g dbSNP:756620526
980 980 a, g dbSNP:750968748
989 989 a, c dbSNP:767722821
991 991 g, t dbSNP:762213071
996 996 a, c, g dbSNP:763736101
997 997 g, t dbSNP:762656136
1009 1009 a, g dbSNP:774927278
1013 1013 c, t dbSNP:769300497
1014 1014 a, g dbSNP:745755397
1021 1021 c, t dbSNP:776653758
1023 1023 c, t dbSNP:770823921
1032 1032 -, tcg dbSNP:571494653
1040 1040 a, g, t dbSNP:777768186
1051 1051 a, c dbSNP:532477443
1052 1052 c, t dbSNP:755192203
1065 1065 g, t dbSNP:62521874
1079 1079 a, c dbSNP:562440203
1090 1090 c, t dbSNP:752414651
1093 1093 a, c, t dbSNP:781504738
1099 1099 c, g dbSNP:781699631
1118 1118 g, t dbSNP:540539212
1167 1167 c, t dbSNP:755419411
1211 1211 a, c dbSNP:528511769
1214 1214 c, g dbSNP:7386685
1221 1221 g, t dbSNP:546331440
1271 1271 a, c dbSNP:575852616
1305 1305 a, g dbSNP:367544686
1308 1308 c, g dbSNP:778434878
1318 1318 a, t dbSNP:4874115
1327 1327 a, g dbSNP:564589828
1373 1373 c, t dbSNP:190155671
1390 1390 c, g dbSNP:555654953
1404 1404 c, t dbSNP:4874114
1420 1420 a, g dbSNP:531161076
1428 1428 a, c dbSNP:566471011
1461 1461 c, t dbSNP:756102533
1467 1467 c, g dbSNP:151038711
1515 1515 a, c dbSNP:539044309
1558 1558 a, g dbSNP:752506274
1589 1589 c, g dbSNP:185105606
1617 1617 a, c dbSNP:550245891
1643 1643 -, ca dbSNP:557811437
1749 1749 c, t dbSNP:529506419
1763 1763 a, g dbSNP:762870647
1772 1772 c, g dbSNP:192494054
1796 1796 a, g dbSNP:201764926
1808 1808 -, g dbSNP:762027194
1808 1808 g, t dbSNP:186830371
1812 1812 a, g dbSNP:13256679
1829 1829 -, g dbSNP:765414727
1839 1839 g, t dbSNP:558535946
1900 1900 c, t dbSNP:564794073
1917 1917 g, t dbSNP:182109280
1920 1920 a, c dbSNP:191860674
1961 1961 a, t dbSNP:187857888
1966 1966 -, a dbSNP:369012845
1966 1966 a, c, t dbSNP:1466621
1967 1967 a, t dbSNP:561690810
2012 2012 g, t dbSNP:73717566
2071 2071 g, t dbSNP:573102349
2090 2090 c, t dbSNP:557608511
2099 2099 g, t dbSNP:142745642
2125 2125 g, t dbSNP:765343723
2129 2129 g, t dbSNP:574860225
2136 2136 a, g dbSNP:1466622
2212 2212 c, t dbSNP:535158894
2214 2214 c, g dbSNP:769267338
2216 2216 c, t dbSNP:761300888
2222 2222 a, g dbSNP:775880935
2236 2236 a, c dbSNP:772342810
2243 2243 a, g dbSNP:139769401
2319 2319 c, t dbSNP:771717599
2320 2320 a, g dbSNP:773712369
2323 2323 a, g dbSNP:745465013
2331 2331 a, c dbSNP:113553054
2367 2367 c, t dbSNP:546920846
2372 2372 c, t dbSNP:191693097
2373 2373 a, t dbSNP:371183187

Target ORF information:

RefSeq Version NM_201589
Organism Homo sapiens (human)
Definition Homo sapiens v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A (MAFA), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_201589

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGGCCGCGG AGCTGGCGAT GGGCGCCGAG CTGCCCAGCA GCCCGCTGGC CATCGAGTAC 
GTCAACGACT TCGACCTGAT GAAGTTCGAG GTGAAGAAGG AGCCTCCCGA GGCCGAGCGC
TTCTGCCACC GCCTGCCGCC AGGCTCGCTG TCCTCGACGC CGCTCAGCAC GCCCTGCTCC
TCCGTGCCCT CCTCGCCCAG CTTCTGCGCG CCCAGCCCGG GCACCGGCGG CGGCGGCGGC
GCGGGGGGCG GCGGCGGCTC GTCTCAGGCC GGGGGCGCCC CCGGGCCGCC GAGCGGGGGC
CCCGGCGCCG TCGGGGGCAC CTCGGGGAAG CCGGCGCTGG AGGATCTGTA CTGGATGAGC
GGCTACCAGC ATCACCTCAA CCCCGAGGCG CTCAACCTGA CGCCCGAGGA CGCGGTGGAG
GCGCTCATCG GCAGCGGCCA CCACGGCGCG CACCACGGCG CGCACCACCC GGCGGCCGCC
GCAGCCTACG AGGCTTTCCG CGGCCCGGGC TTCGCGGGCG GCGGCGGAGC GGACGACATG
GGCGCCGGCC ACCACCACGG CGCGCACCAC GCCGCCCACC ATCACCACGC CGCCCACCAC
CACCACCACC ACCACCACCA CCATGGCGGC GCGGGACACG GCGGTGGCGC GGGCCACCAC
GTGCGCCTGG AGGAGCGCTT CTCCGACGAC CAGCTGGTGT CCATGTCGGT GCGCGAGCTG
AACCGGCAGC TCCGCGGCTT CAGCAAGGAG GAGGTCATCC GGCTCAAGCA GAAGCGGCGC
ACGCTCAAGA ACCGCGGCTA CGCGCAGTCC TGCCGCTTCA AGCGGGTGCA GCAGCGGCAC
ATTCTGGAGA GCGAGAAGTG CCAACTCCAG AGCCAGGTGG AGCAGCTGAA GCTGGAGGTG
GGGCGCCTGG CCAAAGAGCG GGACCTGTAC AAGGAGAAAT ACGAGAAGCT GGCGGGCCGG
GGCGGCCCCG GGAGCGCGGG CGGGGCCGGT TTCCCGCGGG AGCCTTCGCC GCCGCAGGCC
GGTCCCGGCG GGGCCAAGGG CACGGCCGAC TTCTTCCTGT AG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.