The following LPL gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the LPL gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
||ORF Nucleotide Sequence (Length: 1428bp)
||pcDNA3.1+/C-(K)DYK or customized vector
|Tag on pcDNA3.1+/C-(K)DYK
||C terminal DYKDDDDK tags
|ORF Insert Method
||CloneEZ® Seamless cloning technology
||Homo sapiens (human)
||lipoprotein lipase precursor
||REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from DA485210.1, M15856.1 and
This sequence is a reference standard in the RefSeqGene project.
On Apr 13, 2007 this sequence version replaced gi:4557726.
Summary: LPL encodes lipoprotein lipase, which is expressed in
heart, muscle, and adipose tissue. LPL functions as a homodimer,
and has the dual functions of triglyceride hydrolase and
ligand/bridging factor for receptor-mediated lipoprotein uptake.
Severe mutations that cause LPL deficiency result in type I
hyperlipoproteinemia, while less extreme mutations in LPL are
linked to many disorders of lipoprotein metabolism. [provided by
RefSeq, Jul 2008].
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
Transcript exon combination :: M15856.1, BC011353.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
COMPLETENESS: complete on the 3' end.