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LPL lipoprotein lipase [Homo sapiens (human)]

Gene Symbol LPL
Entrez Gene ID 4023
Full Name lipoprotein lipase
Synonyms HDLCQ11, LIPD
General protein information
Preferred Names
lipoprotein lipase
Names
lipoprotein lipase
NP_000228.1
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

8

8p22

Summary LPL encodes lipoprotein lipase, which is expressed in heart, muscle, and adipose tissue. LPL functions as a homodimer, and has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake. Severe mutations that cause LPL deficiency result in type I hyperlipoproteinemia, while less extreme mutations in LPL are linked to many disorders of lipoprotein metabolism. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

609708

Disorder Html: Lipoprotein lipase deficiency, 238600 (3); Combined hyperlipidemia,
CloneID RefSeq Accession Definition **Vector *Turnaround time Price
OHu25014 NM_000237 Homo sapiens lipoprotein lipase (LPL), mRNA. pcDNA3.1-C-(k)DYK In stock 5-7 Starting from $99.00

*Business Day
**You may select a custom vector to replace pcDNA3.1-C-(k)DYK after clone is added to cart.



CloneID OHu25014D
Sequence Information ORF Nucleotide Sequence (Length: 1428bp)
Protein sequence
SNP
Vector pcDNA3.1-C-(k)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1-C-(k)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product lipoprotein lipase precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA485210.1, M15856.1 and AC100802.2. This sequence is a reference standard in the RefSeqGene project. On Apr 13, 2007 this sequence version replaced gi:4557726. Summary: LPL encodes lipoprotein lipase, which is expressed in heart, muscle, and adipose tissue. LPL functions as a homodimer, and has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake. Severe mutations that cause LPL deficiency result in type I hyperlipoproteinemia, while less extreme mutations in LPL are linked to many disorders of lipoprotein metabolism. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M15856.1, BC011353.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGGAGAGCA AAGCCCTGCT CGTGCTGACT CTGGCCGTGT GGCTCCAGAG TCTGACCGCC 
TCCCGCGGAG GGGTGGCCGC CGCCGACCAA AGAAGAGATT TTATCGACAT CGAAAGTAAA
TTTGCCCTAA GGACCCCTGA AGACACAGCT GAGGACACTT GCCACCTCAT TCCCGGAGTA
GCAGAGTCCG TGGCTACCTG TCATTTCAAT CACAGCAGCA AAACCTTCAT GGTGATCCAT
GGCTGGACGG TAACAGGAAT GTATGAGAGT TGGGTGCCAA AACTTGTGGC CGCCCTGTAC
AAGAGAGAAC CAGACTCCAA TGTCATTGTG GTGGACTGGC TGTCACGGGC TCAGGAGCAT
TACCCAGTGT CCGCGGGCTA CACCAAACTG GTGGGACAGG ATGTGGCCCG GTTTATCAAC
TGGATGGAGG AGGAGTTTAA CTACCCTCTG GACAATGTCC ATCTCTTGGG ATACAGCCTT
GGAGCCCATG CTGCTGGCAT TGCAGGAAGT CTGACCAATA AGAAAGTCAA CAGAATTACT
GGCCTCGATC CAGCTGGACC TAACTTTGAG TATGCAGAAG CCCCGAGTCG TCTTTCTCCT
GATGATGCAG ATTTTGTAGA CGTCTTACAC ACATTCACCA GAGGGTCCCC TGGTCGAAGC
ATTGGAATCC AGAAACCAGT TGGGCATGTT GACATTTACC CGAATGGAGG TACTTTTCAG
CCAGGATGTA ACATTGGAGA AGCTATCCGC GTGATTGCAG AGAGAGGACT TGGAGATGTG
GACCAGCTAG TGAAGTGCTC CCACGAGCGC TCCATTCATC TCTTCATCGA CTCTCTGTTG
AATGAAGAAA ATCCAAGTAA GGCCTACAGG TGCAGTTCCA AGGAAGCCTT TGAGAAAGGG
CTCTGCTTGA GTTGTAGAAA GAACCGCTGC AACAATCTGG GCTATGAGAT CAATAAAGTC
AGAGCCAAAA GAAGCAGCAA AATGTACCTG AAGACTCGTT CTCAGATGCC CTACAAAGTC
TTCCATTACC AAGTAAAGAT TCATTTTTCT GGGACTGAGA GTGAAACCCA TACCAATCAG
GCCTTTGAGA TTTCTCTGTA TGGCACCGTG GCCGAGAGTG AGAACATCCC ATTCACTCTG
CCTGAAGTTT CCACAAATAA GACCTACTCC TTCCTAATTT ACACAGAGGT AGATATTGGA
GAACTACTCA TGTTGAAGCT CAAATGGAAG AGTGATTCAT ACTTTAGCTG GTCAGACTGG
TGGAGCAGTC CCGGCTTCGC CATTCAGAAG ATCAGAGTAA AAGCAGGAGA GACTCAGAAA
AAGGTGATCT TCTGTTCTAG GGAGAAAGTG TCTCATTTGC AGAAAGGAAA GGCACCTGCG
GTATTTGTGA AATGCCATGA CAAGTCTCTG AATAAGAAGT CAGGCTGA
The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.
RefSeqNP_000228.1
CDS371..1798
Misc Feature(1)173..175(+)
Misc Feature(2)467..1789(+)
Misc Feature(3)479..1372(+)
Misc Feature(4)839..853(+)
Misc Feature(5)845..1174(+)
Misc Feature(6)1097..1168(+)
Misc Feature(7)1391..1765(+)
Misc Feature(8)1406..1693(+)
Exon (1)1..458
Gene:LPL
Gene Synonym:
Exon (2)459..619
Gene:LPL
Gene Synonym:
Exon (3)620..799
Gene:LPL
Gene Synonym:
Exon (4)800..911
Gene:LPL
Gene Synonym:
Exon (5)912..1145
Gene:LPL
Gene Synonym:
Exon (6)1146..1388
Gene:LPL
Gene Synonym:
Exon (7)1389..1509
Gene:LPL
Gene Synonym:
Exon (8)1510..1692
Gene:LPL
Gene Synonym:
Exon (9)1693..1797
Gene:LPL
Gene Synonym:
Exon (10)1798..3747
Gene:LPL
Gene Synonym:
Translation
Position Chain Variation Link
19 19 c, t dbSNP:535509886
20 20 c, t dbSNP:546116036
81 81 c, g dbSNP:564779858
88 88 g, t dbSNP:80351041
90 90 g, t dbSNP:1800590
107 107 a, t dbSNP:75890454
130 130 c, g dbSNP:540525285
143 143 a, g dbSNP:548255120
155 155 a, t dbSNP:529202525
187 187 a, g dbSNP:185190253
195 195 -, cc dbSNP:146978295
206 206 c, t dbSNP:190484854
251 251 c, g dbSNP:571503297
253 253 c, g dbSNP:745563072
258 258 a, c dbSNP:771569574
264 264 a, g dbSNP:542429534
282 282 c, t dbSNP:538149320
300 300 c, g dbSNP:559590399
308 308 a, c dbSNP:182193170
320 320 -, ct dbSNP:750065070
320 320 a, c dbSNP:775041849
324 324 g, t dbSNP:535892656
330 330 g, t dbSNP:778646681
335 335 c, g dbSNP:750174349
337 337 c, g dbSNP:758350420
344 344 a, g dbSNP:779906116
345 345 c, g dbSNP:747061015
348 348 c, t dbSNP:373898881
349 349 c, t dbSNP:781321057
354 354 a, g dbSNP:376305828
356 356 c, g dbSNP:769870617
357 357 a, g dbSNP:773735260
358 358 c, g dbSNP:763352315
360 360 c, t dbSNP:370686458
361 361 a, g dbSNP:201280837
364 364 -, cc dbSNP:759481116
364 364 c, t dbSNP:774996291
367 367 c, g dbSNP:760160365
368 368 a, g dbSNP:763635553
376 376 a, g dbSNP:753472797
378 378 a, g dbSNP:367592716
385 385 a, c, t dbSNP:554223627
405 405 c, t dbSNP:758119828
406 406 a, c dbSNP:780030692
407 407 g, t dbSNP:751494597
408 408 c, t dbSNP:755056538
413 413 a, c dbSNP:781367198
415 415 c, g dbSNP:748132101
417 417 -, agagtctga dbSNP:765192293
419 419 a, g dbSNP:756418111
425 425 a, c dbSNP:778075626
426 426 c, t dbSNP:749739032
427 427 c, g dbSNP:771409952
428 428 a, g dbSNP:774768909
429 429 c, t dbSNP:572477224
433 433 c, g dbSNP:772418131
438 438 a, g dbSNP:539997018
441 441 c, g dbSNP:761167661
451 451 a, c dbSNP:764871141
453 453 c, t dbSNP:11570895
455 455 c, g dbSNP:762788938
459 459 a, g dbSNP:780666488
469 469 c, t dbSNP:747485781
475 475 c, t dbSNP:145405273
476 476 a, c, g dbSNP:1801177
479 479 a, g dbSNP:538543355
481 481 c, g, t dbSNP:374067507
482 482 a, g dbSNP:557015233
483 483 a, g dbSNP:142501489
504 504 a, c dbSNP:143944126
513 513 a, t dbSNP:367924602
519 519 c, g, t dbSNP:148201569
523 523 a, g dbSNP:141136113
526 526 c, t dbSNP:765559575
527 527 a, g dbSNP:750594245
542 542 c, t dbSNP:758843839
544 544 a, c, t dbSNP:372554872
545 545 a, g, t dbSNP:375484335
552 552 a, c, t dbSNP:748863604
559 559 c, t dbSNP:114726797
560 560 a, g dbSNP:114101772
573 573 a, g dbSNP:150909171
583 583 c, g, t dbSNP:11542065
589 589 c, g dbSNP:768715144
596 596 c, t dbSNP:776702426
612 612 a, g dbSNP:762007406
618 618 c, t dbSNP:372267210
619 619 a, g dbSNP:544872445
624 624 c, g, t dbSNP:182593459
631 631 a, g dbSNP:774547249
634 634 a, t dbSNP:118204065
637 637 c, g dbSNP:767840257
638 638 a, g dbSNP:753068328
642 642 a, g dbSNP:118204070
643 643 a, g dbSNP:756598856
646 646 a, g dbSNP:551959021
656 656 c, g dbSNP:373088068
660 660 c, t dbSNP:201946950
662 662 a, g dbSNP:145657341
663 663 c, t dbSNP:746636536
670 670 a, c dbSNP:118204074
673 673 g, t dbSNP:754858152
675 675 a, g dbSNP:781159405
676 676 a, c dbSNP:118204073
681 681 c, g dbSNP:769624687
695 695 a, g dbSNP:537745634
703 703 a, g, t dbSNP:749390229
707 707 c, t dbSNP:118204069
710 710 c, t dbSNP:774598608
715 715 a, c dbSNP:147309575
716 716 c, t dbSNP:772230128
717 717 a, g dbSNP:775728208
718 718 a, g dbSNP:761030314
720 720 c, t dbSNP:764572032
725 725 a, g dbSNP:549451267
742 742 c, g, t dbSNP:762600466
743 743 a, g dbSNP:199675233
744 744 c, t dbSNP:754692513
745 745 a, c, g dbSNP:780831995
756 756 a, c dbSNP:140903633
758 758 a, c dbSNP:777624170
760 760 a, g dbSNP:568047818
765 765 g, t dbSNP:770817727
766 766 a, t dbSNP:778989703
767 767 c, t dbSNP:118204058
775 775 a, g dbSNP:1121923
779 779 c, g, t dbSNP:376875031
780 780 a, g dbSNP:527267420
805 805 a, g dbSNP:248
806 806 a, t dbSNP:780188625
808 808 -, taac dbSNP:751554200
809 809 a, c dbSNP:747222264
818 818 c, t dbSNP:768718980
826 826 c, t dbSNP:116678290
827 827 c, g dbSNP:748459586
832 832 c, t dbSNP:770491860
836 836 c, t dbSNP:773843594
838 838 a, g dbSNP:759167136
844 844 c, t dbSNP:767027334
850 850 c, t dbSNP:774826283
868 868 c, t dbSNP:760400846
876 876 a, g dbSNP:118204063
878 878 a, t dbSNP:763598285
879 879 a, g dbSNP:753632194
895 895 a, g dbSNP:757038496
898 898 c, g dbSNP:199606532
899 899 a, g dbSNP:750335368
907 907 a, t dbSNP:758448156
910 910 c, t dbSNP:114830374
911 911 g, t dbSNP:747009924
912 912 a, g dbSNP:191402029
913 913 -, cc dbSNP:759607497
917 917 c, g dbSNP:781614031
918 918 a, g dbSNP:118204064
923 923 a, g dbSNP:748349562
925 925 c, t dbSNP:756368813
929 929 c, t dbSNP:200669137
941 941 g, t dbSNP:778308749
942 942 a, t dbSNP:544932321
951 951 c, g dbSNP:771476617
954 954 c, t dbSNP:779281032
955 955 a, g dbSNP:563135472
959 959 c, t dbSNP:768128481
960 960 a, g, t dbSNP:372668179
966 966 c, g, t dbSNP:118204072
968 968 c, t dbSNP:773002707
973 973 g, t dbSNP:762653213
977 977 a, g dbSNP:118204056
988 988 a, g dbSNP:200700551
991 991 c, g, t dbSNP:118204076
992 992 a, g dbSNP:568397156
1001 1001 a, t dbSNP:759702329
1004 1004 c, t dbSNP:767740358
1014 1014 a, g dbSNP:118204057
1015 1015 a, g dbSNP:756420241
1018 1018 c, t dbSNP:140457997
1023 1023 a, g dbSNP:754292853
1028 1028 a, c dbSNP:757546424
1032 1032 c, t dbSNP:118204061
1035 1035 a, g dbSNP:118204075
1046 1046 a, c dbSNP:746327088
1048 1048 a, g dbSNP:558390128
1050 1050 c, t dbSNP:528243561
1053 1053 c, g dbSNP:747598008
1055 1055 c, g dbSNP:769439327
1057 1057 c, t dbSNP:45607438
1059 1059 c, t dbSNP:762857494
1063 1063 c, g dbSNP:118204067
1065 1065 g, t dbSNP:770601263
1069 1069 c, t dbSNP:370261979
1071 1071 c, t dbSNP:118204060
1080 1080 a, g dbSNP:571478179
1083 1083 a, c dbSNP:767509076
1084 1084 a, t dbSNP:752830515
1087 1087 c, t dbSNP:760836457
1099 1099 c, t dbSNP:764464946
1104 1104 g, t dbSNP:114792062
1114 1114 c, t dbSNP:757675785
1118 1118 c, t dbSNP:779172858
1119 1119 a, g dbSNP:750750025
1120 1120 c, t dbSNP:373989588
1121 1121 a, g dbSNP:377128614
1125 1125 c, t dbSNP:118204080
1137 1137 -, taaatatt dbSNP:769832722
1139 1139 c, t dbSNP:755601354
1153 1153 c, t dbSNP:138065727
1156 1156 a, g dbSNP:140986245
1159 1159 a, g dbSNP:775606162
1168 1168 c, g, t dbSNP:118204082
1169 1169 c, t dbSNP:768585624
1174 1174 c, t dbSNP:776585907
1175 1175 a, g dbSNP:761886494
1178 1178 c, t dbSNP:118204077
1179 1179 a, g dbSNP:118204062
1181 1181 a, t dbSNP:118204059
1188 1188 a, g, t dbSNP:773407951
1198 1198 a, c, t dbSNP:766760812
1199 1199 a, g dbSNP:118204068
1201 1201 -, ct dbSNP:773891125
1205 1205 c, g dbSNP:371282890
1206 1206 g, t dbSNP:35414700
1214 1214 g, t dbSNP:533505535
1216 1216 a, c dbSNP:369964351
1218 1218 a, g dbSNP:373463971
1221 1221 a, g dbSNP:778475550
1232 1232 a, c, g dbSNP:1800011
1237 1237 a, c dbSNP:780013139
1256 1256 a, c, g dbSNP:746740949
1261 1261 c, t dbSNP:150120283
1270 1270 a, g dbSNP:748234170
1281 1281 a, g dbSNP:769886647
1283 1283 c, t dbSNP:773235712
1287 1287 c, g dbSNP:763186724
1294 1294 a, c dbSNP:771085188
1295 1295 c, t dbSNP:377421145
1316 1316 a, g dbSNP:369054213
1323 1323 a, g dbSNP:268
1328 1328 g, t dbSNP:767970819
1333 1333 -, a dbSNP:761465531
1336 1336 a, c dbSNP:753229741
1345 1345 c, g dbSNP:761265900
1346 1346 a, g dbSNP:764867247
1351 1351 a, g dbSNP:149247646
1357 1357 a, c dbSNP:118204081
1368 1368 a, g dbSNP:144466625
1369 1369 c, t dbSNP:779784166
1378 1378 a, g dbSNP:751464850
1381 1381 c, g dbSNP:754788836
1385 1385 a, c dbSNP:781039961
1389 1389 c, t dbSNP:756051524
1402 1402 a, t dbSNP:777686682
1403 1403 a, g dbSNP:749430133
1409 1409 a, g dbSNP:757308432
1415 1415 g, t dbSNP:779149891
1418 1418 g, t dbSNP:746129874
1419 1419 c, t dbSNP:199912722
1421 1421 a, g dbSNP:772132247
1423 1423 g, t dbSNP:775934129
1429 1429 c, g dbSNP:747267560
1433 1433 a, g dbSNP:769352815
1437 1437 c, t dbSNP:777263150
1438 1438 c, t dbSNP:762600662
1439 1439 c, g dbSNP:765955744
1444 1444 c, t dbSNP:773686669
1451 1451 a, g dbSNP:118204071
1462 1462 c, t dbSNP:759240391
1464 1464 c, t dbSNP:546542623
1471 1471 c, t dbSNP:752606681
1477 1477 c, g, t dbSNP:200121996
1478 1478 a, g dbSNP:298
1479 1479 c, t dbSNP:757142660
1483 1483 c, g, t dbSNP:750345655
1484 1484 a, c, g dbSNP:753984721
1493 1493 a, g dbSNP:780133524
1496 1496 a, t dbSNP:747433684
1498 1498 c, t dbSNP:299
1505 1505 a, g dbSNP:300
1506 1506 c, g, t dbSNP:76708715
1507 1507 a, t dbSNP:773918283
1509 1509 c, t dbSNP:758966315
1517 1517 a, g dbSNP:771423681
1526 1526 a, g dbSNP:760191608
1533 1533 c, g, t dbSNP:779549741
1534 1534 a, c, t dbSNP:316
1535 1535 c, t dbSNP:761714988
1536 1536 a, c dbSNP:769442590
1539 1539 c, g, t dbSNP:141502542
1544 1544 c, g dbSNP:118204078
1548 1548 c, t dbSNP:762819569
1549 1549 g, t dbSNP:766273113
1550 1550 c, t dbSNP:774640681
1556 1556 c, g dbSNP:759677082
1566 1566 c, t dbSNP:139282874
1571 1571 a, c, g dbSNP:150009614
1580 1580 a, g dbSNP:764392384
1584 1584 g, t dbSNP:754169992
1597 1597 a, g dbSNP:118204066
1600 1600 c, g dbSNP:757705770
1602 1602 c, g dbSNP:146559760
1604 1604 a, c, g dbSNP:541991367
1615 1615 g, t dbSNP:754460034
1627 1627 c, t dbSNP:780861348
1629 1629 a, g dbSNP:747786336
1630 1630 c, g dbSNP:780420738
1635 1635 -, gc dbSNP:749909979
1638 1638 -, g dbSNP:756650310
1640 1640 -, ccc dbSNP:766899541
1642 1642 c, t dbSNP:200852756
1643 1643 a, g dbSNP:546244838
1648 1648 c, t dbSNP:771051928
1649 1649 a, g dbSNP:5934
1656 1656 a, g dbSNP:759733237
1660 1660 g, t dbSNP:767740111
1661 1661 a, t dbSNP:775665524
1665 1665 c, g dbSNP:760824086
1672 1672 a, t dbSNP:587777908
1676 1676 a, g dbSNP:587777909
1684 1684 g, t dbSNP:764305885
1689 1689 a, g dbSNP:754219549
1695 1695 g, t dbSNP:116403115
1699 1699 a, c dbSNP:750737028
1704 1704 a, g dbSNP:118204079
1708 1708 c, t dbSNP:146509813
1712 1712 a, g dbSNP:149089920
1714 1714 a, g dbSNP:143110734
1718 1718 c, g dbSNP:755628740
1725 1725 a, g dbSNP:777332353
1726 1726 a, t dbSNP:753561788
1729 1729 a, g dbSNP:114770016
1732 1732 a, g dbSNP:756924750
1738 1738 a, c dbSNP:151194635
1741 1741 c, g dbSNP:745596838
1743 1743 c, t dbSNP:140236957
1744 1744 a, t dbSNP:780023880
1745 1745 c, t dbSNP:371596985
1749 1749 c, t dbSNP:150319057
1750 1750 a, g dbSNP:768747119
1755 1755 c, t dbSNP:776532284
1759 1759 c, g dbSNP:137934933
1771 1771 a, c dbSNP:769944419
1779 1779 a, t dbSNP:773571137
1781 1781 a, c dbSNP:143388616
1785 1785 a, c dbSNP:763291779
1786 1786 a, g dbSNP:766845869
1788 1788 a, c dbSNP:752077000
1790 1790 c, t dbSNP:759923339
1791 1791 c, g dbSNP:328
1806 1806 c, t dbSNP:765034981
1807 1807 a, g dbSNP:4922115
1808 1808 a, c dbSNP:757950844
1810 1810 g, t dbSNP:766221816
1811 1811 c, t dbSNP:751256031
1816 1816 c, g dbSNP:186402360
1819 1819 c, t dbSNP:780987035
1820 1820 a, g dbSNP:774143556
1826 1826 c, t dbSNP:375896929
1827 1827 a, g dbSNP:7818177
1828 1828 a, g dbSNP:190991033
1831 1831 a, c, t dbSNP:375834511
1834 1834 a, g dbSNP:547662238
1836 1836 a, g dbSNP:770998052
1841 1841 c, g dbSNP:368697813
1849 1849 c, t dbSNP:762551013
1861 1861 a, g dbSNP:538189911
1939 1939 c, g dbSNP:771650764
1956 1956 g, t dbSNP:373148302
1966 1966 c, t dbSNP:556538224
1981 1981 a, g dbSNP:112127349
1999 1999 g, t dbSNP:774883455
2014 2014 c, t dbSNP:568789989
2019 2019 c, t dbSNP:761203901
2029 2029 c, t dbSNP:182757938
2081 2081 -, a dbSNP:59732467
2095 2095 a, g dbSNP:186295779
2133 2133 c, t dbSNP:764473808
2135 2135 a, g dbSNP:754413402
2162 2162 a, c dbSNP:137854428
2169 2169 c, t dbSNP:3289
2187 2187 c, g dbSNP:566726236
2210 2210 -, tactc dbSNP:376029876
2212 2212 -, ctcta dbSNP:374509929
2216 2216 a, t dbSNP:376155590
2235 2235 a, t dbSNP:753801774
2246 2246 c, t dbSNP:191212278
2253 2253 a, c dbSNP:538947347
2264 2264 a, c dbSNP:558623397
2323 2323 a, g dbSNP:750588637
2331 2331 a, g dbSNP:538188089
2351 2351 c, t dbSNP:375147988
2372 2372 a, g dbSNP:758646352
2373 2373 c, t dbSNP:11542064
2409 2409 c, t dbSNP:780145448
2413 2413 c, t dbSNP:544563134
2425 2425 c, t dbSNP:182900923
2446 2446 c, t dbSNP:137854869
2457 2457 a, c dbSNP:779244279
2486 2486 a, g dbSNP:187587525
2509 2509 c, g dbSNP:542281779
2512 2512 c, g dbSNP:371100432
2527 2527 a, g dbSNP:575395509
2538 2538 a, g dbSNP:142494520
2554 2554 a, g dbSNP:80237137
2558 2558 c, g dbSNP:112975576
2589 2589 c, g dbSNP:558988893
2594 2594 a, g dbSNP:11570892
2606 2606 c, g dbSNP:777560616
2620 2620 a, g dbSNP:544101680
2622 2622 a, g dbSNP:1059497
2625 2625 a, t dbSNP:3208305
2629 2629 a, g dbSNP:11570896
2651 2651 c, g, t dbSNP:1803924
2661 2661 c, t dbSNP:535887914
2743 2743 a, g dbSNP:778862660
2746 2746 c, t dbSNP:574891862
2747 2747 a, g dbSNP:11570893
2780 2780 c, t dbSNP:566454006
2800 2800 c, g dbSNP:192278405
2815 2815 c, t dbSNP:542508892
2837 2837 a, g dbSNP:558781321
2864 2864 a, g dbSNP:577137979
2880 2880 c, g dbSNP:760076990
2904 2904 a, g dbSNP:150960886
2905 2905 c, t dbSNP:556207295
2928 2928 a, c dbSNP:527862302
2940 2940 c, t dbSNP:1059507
2957 2957 c, t dbSNP:140767506
2963 2963 a, g dbSNP:560577552
2965 2965 a, c dbSNP:150252331
3019 3019 c, g dbSNP:750821267
3022 3022 a, c dbSNP:3735964
3048 3048 a, g, t dbSNP:3200218
3060 3060 c, t dbSNP:751866874
3069 3069 a, c dbSNP:531801573
3082 3082 c, t dbSNP:551437994
3089 3089 a, g dbSNP:139240067
3100 3100 a, g dbSNP:369640958
3105 3105 c, t dbSNP:562244158
3106 3106 c, g dbSNP:373828745
3113 3113 c, t dbSNP:375355233
3130 3130 a, t dbSNP:544134518
3148 3148 a, c dbSNP:183325288
3156 3156 g, t dbSNP:547867422
3171 3171 a, c, g dbSNP:188947767
3182 3182 a, g dbSNP:533849621
3185 3185 c, t dbSNP:1803923
3200 3200 a, g dbSNP:757280268
3207 3207 g, t dbSNP:570633578
3212 3212 c, t dbSNP:192714638
3214 3214 c, t dbSNP:58998793
3227 3227 c, t dbSNP:184363931
3237 3237 c, t dbSNP:535791549
3265 3265 a, g dbSNP:189691170
3275 3275 c, t dbSNP:377119575
3288 3288 c, t dbSNP:745625952
3319 3319 c, t dbSNP:191751442
3339 3339 a, c dbSNP:572144530
3353 3353 a, t dbSNP:113464150
3355 3355 c, t dbSNP:763035747
3361 3361 -, attaa dbSNP:756539526
3387 3387 a, g dbSNP:758258351
3404 3404 c, t dbSNP:545856723
3428 3428 g, t dbSNP:184244114
3436 3436 c, t dbSNP:576180330
3457 3457 c, t dbSNP:188873991
3458 3458 a, g dbSNP:562346489
3469 3469 c, t dbSNP:13702
3540 3540 c, t dbSNP:1059611
3547 3547 c, t dbSNP:531898209
3581 3581 a, t dbSNP:17091815
3591 3591 a, g dbSNP:767981135
3595 3595 a, g dbSNP:552256660
3601 3601 a, c dbSNP:183619366
3603 3603 -, tt dbSNP:10645926
3603 3603 c, t dbSNP:200877770
3605 3605 g, t dbSNP:188554527
3622 3622 c, t dbSNP:537986804
3624 3624 a, g dbSNP:748618172
3644 3644 cac, taa dbSNP:386723272
3644 3644 c, t dbSNP:15285
3646 3646 a, c dbSNP:3866471
3656 3656 a, g dbSNP:187374932
3661 3661 c, t dbSNP:553667602
3668 3668 a, c dbSNP:557409570
3673 3673 a, g dbSNP:537734510
3675 3675 a, g dbSNP:572077788
3683 3683 c, t dbSNP:763214410
3684 3684 a, g dbSNP:147116359
3711 3711 c, t dbSNP:766835392
3726 3726 c, t dbSNP:79756214
3732 3732 a, g dbSNP:576116583
3743 3743 c, t dbSNP:774371505

Target ORF information:

RefSeq Version NM_000237
Organism Homo sapiens (human)
Definition Homo sapiens lipoprotein lipase (LPL), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1-C-(k)DYK
NM_000237

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGGAGAGCA AAGCCCTGCT CGTGCTGACT CTGGCCGTGT GGCTCCAGAG TCTGACCGCC 
TCCCGCGGAG GGGTGGCCGC CGCCGACCAA AGAAGAGATT TTATCGACAT CGAAAGTAAA
TTTGCCCTAA GGACCCCTGA AGACACAGCT GAGGACACTT GCCACCTCAT TCCCGGAGTA
GCAGAGTCCG TGGCTACCTG TCATTTCAAT CACAGCAGCA AAACCTTCAT GGTGATCCAT
GGCTGGACGG TAACAGGAAT GTATGAGAGT TGGGTGCCAA AACTTGTGGC CGCCCTGTAC
AAGAGAGAAC CAGACTCCAA TGTCATTGTG GTGGACTGGC TGTCACGGGC TCAGGAGCAT
TACCCAGTGT CCGCGGGCTA CACCAAACTG GTGGGACAGG ATGTGGCCCG GTTTATCAAC
TGGATGGAGG AGGAGTTTAA CTACCCTCTG GACAATGTCC ATCTCTTGGG ATACAGCCTT
GGAGCCCATG CTGCTGGCAT TGCAGGAAGT CTGACCAATA AGAAAGTCAA CAGAATTACT
GGCCTCGATC CAGCTGGACC TAACTTTGAG TATGCAGAAG CCCCGAGTCG TCTTTCTCCT
GATGATGCAG ATTTTGTAGA CGTCTTACAC ACATTCACCA GAGGGTCCCC TGGTCGAAGC
ATTGGAATCC AGAAACCAGT TGGGCATGTT GACATTTACC CGAATGGAGG TACTTTTCAG
CCAGGATGTA ACATTGGAGA AGCTATCCGC GTGATTGCAG AGAGAGGACT TGGAGATGTG
GACCAGCTAG TGAAGTGCTC CCACGAGCGC TCCATTCATC TCTTCATCGA CTCTCTGTTG
AATGAAGAAA ATCCAAGTAA GGCCTACAGG TGCAGTTCCA AGGAAGCCTT TGAGAAAGGG
CTCTGCTTGA GTTGTAGAAA GAACCGCTGC AACAATCTGG GCTATGAGAT CAATAAAGTC
AGAGCCAAAA GAAGCAGCAA AATGTACCTG AAGACTCGTT CTCAGATGCC CTACAAAGTC
TTCCATTACC AAGTAAAGAT TCATTTTTCT GGGACTGAGA GTGAAACCCA TACCAATCAG
GCCTTTGAGA TTTCTCTGTA TGGCACCGTG GCCGAGAGTG AGAACATCCC ATTCACTCTG
CCTGAAGTTT CCACAAATAA GACCTACTCC TTCCTAATTT ACACAGAGGT AGATATTGGA
GAACTACTCA TGTTGAAGCT CAAATGGAAG AGTGATTCAT ACTTTAGCTG GTCAGACTGG
TGGAGCAGTC CCGGCTTCGC CATTCAGAAG ATCAGAGTAA AAGCAGGAGA GACTCAGAAA
AAGGTGATCT TCTGTTCTAG GGAGAAAGTG TCTCATTTGC AGAAAGGAAA GGCACCTGCG
GTATTTGTGA AATGCCATGA CAAGTCTCTG AATAAGAAGT CAGGCTGA

The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.