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M6PR mannose-6-phosphate receptor (cation dependent) [Homo sapiens (human)]

Gene Symbol M6PR
Entrez Gene ID 4074
Full Name mannose-6-phosphate receptor (cation dependent)
Synonyms CD-MPR, MPR 46, MPR-46, MPR46, SMPR
General protein information
Preferred Names
cation-dependent mannose-6-phosphate receptor
Names
cation-dependent mannose-6-phosphate receptor
Mr 46,000 Man6PR
CD Man-6-P receptor
small mannose 6-phosphate receptor
46-kDa mannose 6-phosphate receptor
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

12

12p13

Summary This gene encodes a member of the P-type lectin family. P-type lectins play a critical role in lysosome function through the specific transport of mannose-6-phosphate-containing acid hydrolases from the Golgi complex to lysosomes. The encoded protein functions as a homodimer and requires divalent cations for ligand binding. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome X. [provided by RefSeq, May 2011]. lac of sum
Disorder MIM:

154540

Disorder Html:
CloneID RefSeq Accession Definition **Vector *Turnaround time Price
OHu19246 XM_005253376 PREDICTED: Homo sapiens mannose-6-phosphate receptor (cation dependent) (M6PR), transcript variant X1, mRNA. pcDNA3.1-C-(k)DYK In stock 5-7 Starting from $99.00
OHu19246 XM_011520672 PREDICTED: Homo sapiens mannose-6-phosphate receptor (cation dependent) (M6PR), transcript variant X2, mRNA. pcDNA3.1-C-(k)DYK In stock 5-7 Starting from $99.00
OHu19246 NM_002355 Homo sapiens mannose-6-phosphate receptor (cation dependent) (M6PR), transcript variant 1, mRNA. pcDNA3.1-C-(k)DYK In stock 5-7 Starting from $99.00
OHu19557 NM_001207024 Homo sapiens mannose-6-phosphate receptor (cation dependent) (M6PR), transcript variant 2, mRNA. pcDNA3.1-C-(k)DYK Not in stock 7-9 Starting from $99.00

*Business Day
**You may select a custom vector to replace pcDNA3.1-C-(k)DYK after clone is added to cart.



CloneID OHu19246D
Sequence Information ORF Nucleotide Sequence (Length: 834bp)
Protein sequence
SNP
Vector pcDNA3.1-C-(k)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1-C-(k)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product cation-dependent mannose-6-phosphate receptor isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_009714.18) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGTTCCCTT TCTACAGCTG CTGGAGGACT GGACTGCTAC TACTACTCCT GGCTGTGGCA 
GTGAGAGAAT CCTGGCAGAC AGAAGAAAAA ACTTGCGACT TGGTAGGAGA AAAGGGTAAA
GAGTCAGAGA AAGAGTTGGC TCTAGTGAAG AGGCTGAAAC CACTGTTTAA TAAAAGCTTT
GAGAGCACTG TGGGCCAGGG TTCAGACACA TACATCTACA TCTTCAGGGT GTGCCGGGAA
GCTGGCAACC ACACTTCTGG GGCAGGCCTG GTGCAAATCA ACAAAAGTAA TGGGAAGGAG
ACAGTGGTAG GGAGACTCAA CGAGACTCAC ATCTTCAACG GAAGTAATTG GATCATGCTG
ATCTATAAAG GGGGTGATGA ATATGACAAC CACTGTGGCA AGGAGCAGCG TCGTGCAGTG
GTGATGATCT CCTGCAATCG ACACACCCTA GCGGACAATT TTAACCCTGT GTCTGAGGAG
CGTGGCAAAG TCCAAGATTG TTTCTACCTC TTTGAGATGG ATAGCAGCCT GGCCTGTTCA
CCAGAGATCT CCCACCTCAG TGTGGGTTCC ATCTTACTTG TCACGTTTGC ATCACTGGTT
GCTGTTTATG TTGTTGGGGG GTTCCTATAC CAGCGACTGG TAGTGGGAGC CAAAGGAATG
GAGCAGTTTC CCCACTTAGC CTTCTGGCAG GATCTTGGCA ACCTGGTAGC AGATGGCTGT
GACTTTGTCT GCCGTTCTAA ACCTCGAAAT GTGCCTGCAG CATATCGTGG TGTGGGGGAT
GACCAGCTGG GGGAGGAGTC AGAAGAAAGG GATGACCATT TATTACCAAT GTAG
The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.
RefSeqXP_005253433.1
CDS138..971
Misc Feature(1)138..968(+)
Translation
Position Chain Variation Link
47 47 c, t dbSNP:118024478
60 60 c, t dbSNP:1805756
107 107 c, t dbSNP:778458652
110 110 a, g dbSNP:185262924
132 132 c, g dbSNP:145933352
135 135 a, g dbSNP:118082325
139 139 -, gtt dbSNP:3217106
140 140 a, g dbSNP:772711346
141 141 c, t dbSNP:771529017
142 142 -, gtt dbSNP:149871778
142 142 -, t dbSNP:756356392
143 143 -, ttg dbSNP:767607953
143 143 c, g dbSNP:763470756
150 150 c, t dbSNP:372848083
155 155 a, c dbSNP:770231911
167 167 g, t dbSNP:746210877
174 174 c, g dbSNP:781538590
175 175 -, gct dbSNP:759574090
176 176 a, g dbSNP:769178316
178 178 c, t dbSNP:777962948
182 182 a, c, g dbSNP:757927047
189 189 a, g dbSNP:368554918
196 196 c, t dbSNP:544775120
198 198 a, g dbSNP:373741481
202 202 c, g dbSNP:186943969
210 210 c, t dbSNP:74060247
212 212 c, g dbSNP:778685998
214 214 a, c, g dbSNP:753587485
230 230 c, t dbSNP:766131528
233 233 c, t dbSNP:142181775
239 239 a, g dbSNP:753001030
240 240 a, g dbSNP:750026229
244 244 a, g dbSNP:371194442
252 252 -, ggtaaag dbSNP:774339933
263 263 a, g dbSNP:776406228
272 272 c, g dbSNP:776041703
273 273 c, t dbSNP:201993451
287 287 -, g dbSNP:766480319
300 300 c, g dbSNP:760032961
301 301 -, tgttta dbSNP:761032764
309 309 a, g dbSNP:367682581
322 322 a, g dbSNP:761090519
324 324 a, c dbSNP:773637333
328 328 c, t dbSNP:772434969
337 337 a, g dbSNP:748312435
342 342 c, g dbSNP:774326282
345 345 a, g dbSNP:144462453
351 351 a, g dbSNP:749229647
353 353 c, t dbSNP:370445736
355 355 -, acatct dbSNP:768184902
366 366 a, g dbSNP:769640823
372 372 c, t dbSNP:745646581
373 373 a, g dbSNP:150843100
378 378 g, t dbSNP:756909714
385 385 a, g dbSNP:751187988
394 394 a, c dbSNP:777174588
414 414 a, g dbSNP:377395466
418 418 a, g dbSNP:554202436
422 422 a, g dbSNP:766990238
423 423 a, c dbSNP:761180599
424 424 c, g dbSNP:141476053
425 425 c, t dbSNP:767951449
428 428 c, t dbSNP:149269744
440 440 a, g dbSNP:774609275
444 444 a, g dbSNP:374175866
445 445 g, t dbSNP:763080318
458 458 c, t dbSNP:775345858
459 459 a, g dbSNP:769734088
476 476 c, t dbSNP:771548515
484 484 a, c, g dbSNP:758246039
494 494 a, g dbSNP:201435657
503 503 c, t dbSNP:747714515
507 507 a, g dbSNP:778586736
508 508 a, g dbSNP:754513738
515 515 c, t dbSNP:530866311
526 526 a, g dbSNP:746415937
538 538 a, g dbSNP:781762411
547 547 a, g dbSNP:780103335
549 549 c, t dbSNP:145135342
557 557 a, g dbSNP:764296124
568 568 -, cct dbSNP:756515600
576 576 a, c dbSNP:758680325
577 577 a, g dbSNP:752870627
579 579 c, t dbSNP:374400313
580 580 a, g dbSNP:112549790
587 587 a, t dbSNP:759584808
589 589 c, g dbSNP:776616054
595 595 a, g dbSNP:769139831
606 606 a, g dbSNP:747603655
613 613 a, c dbSNP:778115455
635 635 c, t dbSNP:772559347
653 653 a, g dbSNP:748499477
670 670 c, t dbSNP:779190970
679 679 c, t dbSNP:755199180
689 689 c, t dbSNP:41314131
711 711 g, t dbSNP:200350630
726 726 a, g dbSNP:749563408
732 732 c, g dbSNP:143053831
736 736 g, t dbSNP:756275437
739 739 c, t dbSNP:765573996
747 747 a, g dbSNP:781263673
755 755 a, g dbSNP:757288363
764 764 a, g dbSNP:751491407
777 777 g, t dbSNP:764033209
781 781 c, t dbSNP:762814168
782 782 a, g dbSNP:752465402
783 783 g, t dbSNP:764788256
784 784 a, g dbSNP:759170416
787 787 c, t dbSNP:776010315
812 812 c, t dbSNP:765837224
817 817 c, t dbSNP:138457797
829 829 a, t dbSNP:774806924
834 834 a, g dbSNP:769075317
835 835 c, g dbSNP:749602677
846 846 c, g dbSNP:775862469
847 847 c, t dbSNP:769909324
854 854 c, t dbSNP:376340278
880 880 c, t dbSNP:777052599
881 881 c, t dbSNP:771291436
888 888 a, c, g, t dbSNP:143820587
896 896 a, g dbSNP:748087382
899 899 a, g dbSNP:778903133
900 900 c, t dbSNP:768391620
903 903 c, t dbSNP:749091380
905 905 a, t dbSNP:779753036
911 911 a, g dbSNP:371191352
912 912 c, g dbSNP:41314137
915 915 -, g dbSNP:748518678
923 923 c, g dbSNP:750028342
933 933 a, g dbSNP:780614862
937 937 c, t dbSNP:756758673
954 954 c, t dbSNP:753213027
960 960 g, t dbSNP:765762629
973 973 c, t dbSNP:774005170
977 977 a, c dbSNP:754259156
982 982 a, g, t dbSNP:377063084
983 983 -, t dbSNP:781416108
987 987 g, t dbSNP:773549234
989 989 c, g dbSNP:772087159
992 992 c, g dbSNP:370759645
996 996 -, ttc dbSNP:755158874
1007 1007 -, cccaaacc dbSNP:764054289
1015 1015 a, g dbSNP:762343404
1089 1089 c, t dbSNP:1803933
1112 1112 c, t dbSNP:753633516
1113 1113 c, t dbSNP:775326685
1115 1115 c, t dbSNP:1803934
1121 1121 a, g dbSNP:537006596
1144 1144 a, c dbSNP:140430754
1145 1145 c, t dbSNP:772031462
1170 1170 a, g dbSNP:763043445
1182 1182 a, g dbSNP:748228346
1218 1218 -, ag dbSNP:571345715
1224 1224 c, t dbSNP:770031444
1225 1225 c, t dbSNP:755222376
1240 1240 c, t dbSNP:551454985
1263 1263 c, t dbSNP:774585757
1341 1341 -, cttt dbSNP:752745079
1350 1350 a, g dbSNP:745364914
1358 1358 -, a dbSNP:143732744
1358 1358 -, a dbSNP:781608267
1365 1365 c, t dbSNP:554446578
1441 1441 a, t dbSNP:35031864
1465 1465 c, t dbSNP:771366585
1471 1471 g, t dbSNP:1049949
1489 1489 c, t dbSNP:756554801
1496 1496 c, t dbSNP:369791155
1499 1499 c, t dbSNP:778382478
1555 1555 a, g dbSNP:768159745
1596 1596 a, g dbSNP:752228433
1598 1598 a, t dbSNP:778326244
1608 1608 c, t dbSNP:763794596
1709 1709 c, t dbSNP:753488829
2191 2191 a, c, g dbSNP:8639
2191 2191 c, t dbSNP:770124281
2277 2277 -, t dbSNP:201697448
2278 2278 -, t dbSNP:775667584
2300 2300 c, t dbSNP:750243531
2346 2346 c, t dbSNP:776530188
2377 2377 a, c dbSNP:761699451
2384 2384 c, t dbSNP:6832

Target ORF information:

RefSeq Version XM_005253376
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens mannose-6-phosphate receptor (cation dependent) (M6PR), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1-C-(k)DYK
XM_005253376

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGTTCCCTT TCTACAGCTG CTGGAGGACT GGACTGCTAC TACTACTCCT GGCTGTGGCA 
GTGAGAGAAT CCTGGCAGAC AGAAGAAAAA ACTTGCGACT TGGTAGGAGA AAAGGGTAAA
GAGTCAGAGA AAGAGTTGGC TCTAGTGAAG AGGCTGAAAC CACTGTTTAA TAAAAGCTTT
GAGAGCACTG TGGGCCAGGG TTCAGACACA TACATCTACA TCTTCAGGGT GTGCCGGGAA
GCTGGCAACC ACACTTCTGG GGCAGGCCTG GTGCAAATCA ACAAAAGTAA TGGGAAGGAG
ACAGTGGTAG GGAGACTCAA CGAGACTCAC ATCTTCAACG GAAGTAATTG GATCATGCTG
ATCTATAAAG GGGGTGATGA ATATGACAAC CACTGTGGCA AGGAGCAGCG TCGTGCAGTG
GTGATGATCT CCTGCAATCG ACACACCCTA GCGGACAATT TTAACCCTGT GTCTGAGGAG
CGTGGCAAAG TCCAAGATTG TTTCTACCTC TTTGAGATGG ATAGCAGCCT GGCCTGTTCA
CCAGAGATCT CCCACCTCAG TGTGGGTTCC ATCTTACTTG TCACGTTTGC ATCACTGGTT
GCTGTTTATG TTGTTGGGGG GTTCCTATAC CAGCGACTGG TAGTGGGAGC CAAAGGAATG
GAGCAGTTTC CCCACTTAGC CTTCTGGCAG GATCTTGGCA ACCTGGTAGC AGATGGCTGT
GACTTTGTCT GCCGTTCTAA ACCTCGAAAT GTGCCTGCAG CATATCGTGG TGTGGGGGAT
GACCAGCTGG GGGAGGAGTC AGAAGAAAGG GATGACCATT TATTACCAAT GTAG

The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.


CloneID OHu19246D
Sequence Information ORF Nucleotide Sequence (Length: 834bp)
Protein sequence
SNP
Vector pcDNA3.1-C-(k)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1-C-(k)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product cation-dependent mannose-6-phosphate receptor isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_009714.18) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGTTCCCTT TCTACAGCTG CTGGAGGACT GGACTGCTAC TACTACTCCT GGCTGTGGCA 
GTGAGAGAAT CCTGGCAGAC AGAAGAAAAA ACTTGCGACT TGGTAGGAGA AAAGGGTAAA
GAGTCAGAGA AAGAGTTGGC TCTAGTGAAG AGGCTGAAAC CACTGTTTAA TAAAAGCTTT
GAGAGCACTG TGGGCCAGGG TTCAGACACA TACATCTACA TCTTCAGGGT GTGCCGGGAA
GCTGGCAACC ACACTTCTGG GGCAGGCCTG GTGCAAATCA ACAAAAGTAA TGGGAAGGAG
ACAGTGGTAG GGAGACTCAA CGAGACTCAC ATCTTCAACG GAAGTAATTG GATCATGCTG
ATCTATAAAG GGGGTGATGA ATATGACAAC CACTGTGGCA AGGAGCAGCG TCGTGCAGTG
GTGATGATCT CCTGCAATCG ACACACCCTA GCGGACAATT TTAACCCTGT GTCTGAGGAG
CGTGGCAAAG TCCAAGATTG TTTCTACCTC TTTGAGATGG ATAGCAGCCT GGCCTGTTCA
CCAGAGATCT CCCACCTCAG TGTGGGTTCC ATCTTACTTG TCACGTTTGC ATCACTGGTT
GCTGTTTATG TTGTTGGGGG GTTCCTATAC CAGCGACTGG TAGTGGGAGC CAAAGGAATG
GAGCAGTTTC CCCACTTAGC CTTCTGGCAG GATCTTGGCA ACCTGGTAGC AGATGGCTGT
GACTTTGTCT GCCGTTCTAA ACCTCGAAAT GTGCCTGCAG CATATCGTGG TGTGGGGGAT
GACCAGCTGG GGGAGGAGTC AGAAGAAAGG GATGACCATT TATTACCAAT GTAG
The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.
RefSeqXP_011518974.1
CDS967..1800
Misc Feature(1)967..1797(+)
Translation
Position Chain Variation Link
22 22 c, t dbSNP:747340877
92 92 -, t dbSNP:34516990
170 170 -, a dbSNP:199863898
182 182 -, a dbSNP:577152987
182 182 a, c dbSNP:766542220
183 183 -, a, aa dbSNP:778329432
183 183 a, c dbSNP:12296353
186 186 -, c dbSNP:200250192
187 187 -, a dbSNP:753657518
291 291 -, ct dbSNP:767688647
325 325 c, t dbSNP:112074782
366 366 c, t dbSNP:780535555
382 382 a, g dbSNP:537173567
388 388 -, taat dbSNP:751536125
395 395 c, t dbSNP:185714028
453 453 g, t dbSNP:149000987
489 489 a, t dbSNP:779107992
553 553 a, g dbSNP:193139485
584 584 g, t dbSNP:753288543
605 605 a, c dbSNP:754068700
606 606 a, g dbSNP:775164973
650 650 a, g dbSNP:761020101
671 671 a, g dbSNP:372720227
692 692 c, t dbSNP:760297529
731 731 g, t dbSNP:146909177
740 740 a, t dbSNP:142328810
743 743 c, t dbSNP:187876781
748 748 a, t dbSNP:752418116
779 779 c, t dbSNP:569460063
804 804 -, a dbSNP:35977618
811 811 c, t dbSNP:746892852
821 821 a, g dbSNP:767391308
846 846 a, g dbSNP:115829965
888 888 c, g dbSNP:369624490
889 889 a, g dbSNP:759437342
931 931 c, t dbSNP:182395215
968 968 -, gtt dbSNP:3217106
969 969 a, g dbSNP:772711346
970 970 c, t dbSNP:771529017
971 971 -, gtt dbSNP:149871778
971 971 -, t dbSNP:756356392
972 972 -, ttg dbSNP:767607953
972 972 c, g dbSNP:763470756
979 979 c, t dbSNP:372848083
984 984 a, c dbSNP:770231911
996 996 g, t dbSNP:746210877
1003 1003 c, g dbSNP:781538590
1004 1004 -, gct dbSNP:759574090
1005 1005 a, g dbSNP:769178316
1007 1007 c, t dbSNP:777962948
1011 1011 a, c, g dbSNP:757927047
1018 1018 a, g dbSNP:368554918
1025 1025 c, t dbSNP:544775120
1027 1027 a, g dbSNP:373741481
1031 1031 c, g dbSNP:186943969
1039 1039 c, t dbSNP:74060247
1041 1041 c, g dbSNP:778685998
1043 1043 a, c, g dbSNP:753587485
1059 1059 c, t dbSNP:766131528
1062 1062 c, t dbSNP:142181775
1068 1068 a, g dbSNP:753001030
1069 1069 a, g dbSNP:750026229
1073 1073 a, g dbSNP:371194442
1081 1081 -, ggtaaag dbSNP:774339933
1092 1092 a, g dbSNP:776406228
1101 1101 c, g dbSNP:776041703
1102 1102 c, t dbSNP:201993451
1116 1116 -, g dbSNP:766480319
1129 1129 c, g dbSNP:760032961
1130 1130 -, tgttta dbSNP:761032764
1138 1138 a, g dbSNP:367682581
1151 1151 a, g dbSNP:761090519
1153 1153 a, c dbSNP:773637333
1157 1157 c, t dbSNP:772434969
1166 1166 a, g dbSNP:748312435
1171 1171 c, g dbSNP:774326282
1174 1174 a, g dbSNP:144462453
1180 1180 a, g dbSNP:749229647
1182 1182 c, t dbSNP:370445736
1184 1184 -, acatct dbSNP:768184902
1195 1195 a, g dbSNP:769640823
1201 1201 c, t dbSNP:745646581
1202 1202 a, g dbSNP:150843100
1207 1207 g, t dbSNP:756909714
1214 1214 a, g dbSNP:751187988
1223 1223 a, c dbSNP:777174588
1243 1243 a, g dbSNP:377395466
1247 1247 a, g dbSNP:554202436
1251 1251 a, g dbSNP:766990238
1252 1252 a, c dbSNP:761180599
1253 1253 c, g dbSNP:141476053
1254 1254 c, t dbSNP:767951449
1257 1257 c, t dbSNP:149269744
1269 1269 a, g dbSNP:774609275
1273 1273 a, g dbSNP:374175866
1274 1274 g, t dbSNP:763080318
1287 1287 c, t dbSNP:775345858
1288 1288 a, g dbSNP:769734088
1305 1305 c, t dbSNP:771548515
1313 1313 a, c, g dbSNP:758246039
1323 1323 a, g dbSNP:201435657
1332 1332 c, t dbSNP:747714515
1336 1336 a, g dbSNP:778586736
1337 1337 a, g dbSNP:754513738
1344 1344 c, t dbSNP:530866311
1355 1355 a, g dbSNP:746415937
1367 1367 a, g dbSNP:781762411
1376 1376 a, g dbSNP:780103335
1378 1378 c, t dbSNP:145135342
1386 1386 a, g dbSNP:764296124
1397 1397 -, cct dbSNP:756515600
1405 1405 a, c dbSNP:758680325
1406 1406 a, g dbSNP:752870627
1408 1408 c, t dbSNP:374400313
1409 1409 a, g dbSNP:112549790
1416 1416 a, t dbSNP:759584808
1418 1418 c, g dbSNP:776616054
1424 1424 a, g dbSNP:769139831
1435 1435 a, g dbSNP:747603655
1442 1442 a, c dbSNP:778115455
1464 1464 c, t dbSNP:772559347
1482 1482 a, g dbSNP:748499477
1499 1499 c, t dbSNP:779190970
1508 1508 c, t dbSNP:755199180
1518 1518 c, t dbSNP:41314131
1540 1540 g, t dbSNP:200350630
1555 1555 a, g dbSNP:749563408
1561 1561 c, g dbSNP:143053831
1565 1565 g, t dbSNP:756275437
1568 1568 c, t dbSNP:765573996
1576 1576 a, g dbSNP:781263673
1584 1584 a, g dbSNP:757288363
1593 1593 a, g dbSNP:751491407
1606 1606 g, t dbSNP:764033209
1610 1610 c, t dbSNP:762814168
1611 1611 a, g dbSNP:752465402
1612 1612 g, t dbSNP:764788256
1613 1613 a, g dbSNP:759170416
1616 1616 c, t dbSNP:776010315
1641 1641 c, t dbSNP:765837224
1646 1646 c, t dbSNP:138457797
1658 1658 a, t dbSNP:774806924
1663 1663 a, g dbSNP:769075317
1664 1664 c, g dbSNP:749602677
1675 1675 c, g dbSNP:775862469
1676 1676 c, t dbSNP:769909324
1683 1683 c, t dbSNP:376340278
1709 1709 c, t dbSNP:777052599
1710 1710 c, t dbSNP:771291436
1717 1717 a, c, g, t dbSNP:143820587
1725 1725 a, g dbSNP:748087382
1728 1728 a, g dbSNP:778903133
1729 1729 c, t dbSNP:768391620
1732 1732 c, t dbSNP:749091380
1734 1734 a, t dbSNP:779753036
1740 1740 a, g dbSNP:371191352
1741 1741 c, g dbSNP:41314137
1744 1744 -, g dbSNP:748518678
1752 1752 c, g dbSNP:750028342
1762 1762 a, g dbSNP:780614862
1766 1766 c, t dbSNP:756758673
1783 1783 c, t dbSNP:753213027
1789 1789 g, t dbSNP:765762629
1802 1802 c, t dbSNP:774005170
1806 1806 a, c dbSNP:754259156
1811 1811 a, g, t dbSNP:377063084
1812 1812 -, t dbSNP:781416108
1816 1816 g, t dbSNP:773549234
1818 1818 c, g dbSNP:772087159
1821 1821 c, g dbSNP:370759645
1825 1825 -, ttc dbSNP:755158874
1836 1836 -, cccaaacc dbSNP:764054289
1844 1844 a, g dbSNP:762343404
1918 1918 c, t dbSNP:1803933
1941 1941 c, t dbSNP:753633516
1942 1942 c, t dbSNP:775326685
1944 1944 c, t dbSNP:1803934
1950 1950 a, g dbSNP:537006596
1973 1973 a, c dbSNP:140430754
1974 1974 c, t dbSNP:772031462
1999 1999 a, g dbSNP:763043445
2011 2011 a, g dbSNP:748228346
2047 2047 -, ag dbSNP:571345715
2053 2053 c, t dbSNP:770031444
2054 2054 c, t dbSNP:755222376
2069 2069 c, t dbSNP:551454985
2092 2092 c, t dbSNP:774585757
2170 2170 -, cttt dbSNP:752745079
2179 2179 a, g dbSNP:745364914
2187 2187 -, a dbSNP:143732744
2187 2187 -, a dbSNP:781608267
2194 2194 c, t dbSNP:554446578
2270 2270 a, t dbSNP:35031864
2294 2294 c, t dbSNP:771366585
2300 2300 g, t dbSNP:1049949
2318 2318 c, t dbSNP:756554801
2325 2325 c, t dbSNP:369791155
2328 2328 c, t dbSNP:778382478
2384 2384 a, g dbSNP:768159745
2425 2425 a, g dbSNP:752228433
2427 2427 a, t dbSNP:778326244
2437 2437 c, t dbSNP:763794596
2538 2538 c, t dbSNP:753488829
3020 3020 a, c, g dbSNP:8639
3020 3020 c, t dbSNP:770124281
3106 3106 -, t dbSNP:201697448
3107 3107 -, t dbSNP:775667584
3129 3129 c, t dbSNP:750243531
3175 3175 c, t dbSNP:776530188
3206 3206 a, c dbSNP:761699451
3213 3213 c, t dbSNP:6832

Target ORF information:

RefSeq Version XM_011520672
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens mannose-6-phosphate receptor (cation dependent) (M6PR), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1-C-(k)DYK
XM_011520672

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGTTCCCTT TCTACAGCTG CTGGAGGACT GGACTGCTAC TACTACTCCT GGCTGTGGCA 
GTGAGAGAAT CCTGGCAGAC AGAAGAAAAA ACTTGCGACT TGGTAGGAGA AAAGGGTAAA
GAGTCAGAGA AAGAGTTGGC TCTAGTGAAG AGGCTGAAAC CACTGTTTAA TAAAAGCTTT
GAGAGCACTG TGGGCCAGGG TTCAGACACA TACATCTACA TCTTCAGGGT GTGCCGGGAA
GCTGGCAACC ACACTTCTGG GGCAGGCCTG GTGCAAATCA ACAAAAGTAA TGGGAAGGAG
ACAGTGGTAG GGAGACTCAA CGAGACTCAC ATCTTCAACG GAAGTAATTG GATCATGCTG
ATCTATAAAG GGGGTGATGA ATATGACAAC CACTGTGGCA AGGAGCAGCG TCGTGCAGTG
GTGATGATCT CCTGCAATCG ACACACCCTA GCGGACAATT TTAACCCTGT GTCTGAGGAG
CGTGGCAAAG TCCAAGATTG TTTCTACCTC TTTGAGATGG ATAGCAGCCT GGCCTGTTCA
CCAGAGATCT CCCACCTCAG TGTGGGTTCC ATCTTACTTG TCACGTTTGC ATCACTGGTT
GCTGTTTATG TTGTTGGGGG GTTCCTATAC CAGCGACTGG TAGTGGGAGC CAAAGGAATG
GAGCAGTTTC CCCACTTAGC CTTCTGGCAG GATCTTGGCA ACCTGGTAGC AGATGGCTGT
GACTTTGTCT GCCGTTCTAA ACCTCGAAAT GTGCCTGCAG CATATCGTGG TGTGGGGGAT
GACCAGCTGG GGGAGGAGTC AGAAGAAAGG GATGACCATT TATTACCAAT GTAG

The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.


CloneID OHu19246D
Sequence Information ORF Nucleotide Sequence (Length: 834bp)
Protein sequence
SNP
Vector pcDNA3.1-C-(k)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1-C-(k)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product cation-dependent mannose-6-phosphate receptor isoform 1 precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC341018.1, M16985.1 and AA648974.1. On May 19, 2011 this sequence version replaced gi:10947032. Summary: This gene encodes a member of the P-type lectin family. P-type lectins play a critical role in lysosome function through the specific transport of mannose-6-phosphate-containing acid hydrolases from the Golgi complex to lysosomes. The encoded protein functions as a homodimer and requires divalent cations for ligand binding. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome X. [provided by RefSeq, May 2011]. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC024206.1, M16985.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2149178 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGTTCCCTT TCTACAGCTG CTGGAGGACT GGACTGCTAC TACTACTCCT GGCTGTGGCA 
GTGAGAGAAT CCTGGCAGAC AGAAGAAAAA ACTTGCGACT TGGTAGGAGA AAAGGGTAAA
GAGTCAGAGA AAGAGTTGGC TCTAGTGAAG AGGCTGAAAC CACTGTTTAA TAAAAGCTTT
GAGAGCACTG TGGGCCAGGG TTCAGACACA TACATCTACA TCTTCAGGGT GTGCCGGGAA
GCTGGCAACC ACACTTCTGG GGCAGGCCTG GTGCAAATCA ACAAAAGTAA TGGGAAGGAG
ACAGTGGTAG GGAGACTCAA CGAGACTCAC ATCTTCAACG GAAGTAATTG GATCATGCTG
ATCTATAAAG GGGGTGATGA ATATGACAAC CACTGTGGCA AGGAGCAGCG TCGTGCAGTG
GTGATGATCT CCTGCAATCG ACACACCCTA GCGGACAATT TTAACCCTGT GTCTGAGGAG
CGTGGCAAAG TCCAAGATTG TTTCTACCTC TTTGAGATGG ATAGCAGCCT GGCCTGTTCA
CCAGAGATCT CCCACCTCAG TGTGGGTTCC ATCTTACTTG TCACGTTTGC ATCACTGGTT
GCTGTTTATG TTGTTGGGGG GTTCCTATAC CAGCGACTGG TAGTGGGAGC CAAAGGAATG
GAGCAGTTTC CCCACTTAGC CTTCTGGCAG GATCTTGGCA ACCTGGTAGC AGATGGCTGT
GACTTTGTCT GCCGTTCTAA ACCTCGAAAT GTGCCTGCAG CATATCGTGG TGTGGGGGAT
GACCAGCTGG GGGAGGAGTC AGAAGAAAGG GATGACCATT TATTACCAAT GTAG
The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.
RefSeqNP_002346.1
CDS276..1109
Misc Feature(1)106..106(+)
Misc Feature(2)243..245(+)
Misc Feature(3)276..1106(+)
Misc Feature(4)831..905(+)
Exon (1)1..274
Gene:M6PR
Gene Synonym:
Exon (2)275..451
Gene:M6PR
Gene Synonym:
Exon (3)452..618
Gene:M6PR
Gene Synonym:
Exon (4)619..728
Gene:M6PR
Gene Synonym:
Exon (5)729..859
Gene:M6PR
Gene Synonym:
Exon (6)860..986
Gene:M6PR
Gene Synonym:
Exon (7)987..2566
Gene:M6PR
Gene Synonym:
Translation
Position Chain Variation Link
52 52 a, c dbSNP:753923489
111 111 -, g dbSNP:781043598
117 117 a, c dbSNP:780179610
135 135 c, g dbSNP:765469415
139 139 c, t dbSNP:746937635
179 179 g, t dbSNP:761387333
194 194 c, g dbSNP:546946822
224 224 a, g dbSNP:750736029
228 228 a, g dbSNP:149321629
277 277 -, gtt dbSNP:3217106
278 278 a, g dbSNP:772711346
279 279 c, t dbSNP:771529017
280 280 -, gtt dbSNP:149871778
280 280 -, t dbSNP:756356392
281 281 -, ttg dbSNP:767607953
281 281 c, g dbSNP:763470756
288 288 c, t dbSNP:372848083
293 293 a, c dbSNP:770231911
305 305 g, t dbSNP:746210877
312 312 c, g dbSNP:781538590
313 313 -, gct dbSNP:759574090
314 314 a, g dbSNP:769178316
316 316 c, t dbSNP:777962948
320 320 a, c, g dbSNP:757927047
327 327 a, g dbSNP:368554918
334 334 c, t dbSNP:544775120
336 336 a, g dbSNP:373741481
340 340 c, g dbSNP:186943969
348 348 c, t dbSNP:74060247
350 350 c, g dbSNP:778685998
352 352 a, c, g dbSNP:753587485
368 368 c, t dbSNP:766131528
371 371 c, t dbSNP:142181775
377 377 a, g dbSNP:753001030
378 378 a, g dbSNP:750026229
382 382 a, g dbSNP:371194442
390 390 -, ggtaaag dbSNP:774339933
401 401 a, g dbSNP:776406228
410 410 c, g dbSNP:776041703
411 411 c, t dbSNP:201993451
425 425 -, g dbSNP:766480319
438 438 c, g dbSNP:760032961
439 439 -, tgttta dbSNP:761032764
447 447 a, g dbSNP:367682581
460 460 a, g dbSNP:761090519
462 462 a, c dbSNP:773637333
466 466 c, t dbSNP:772434969
475 475 a, g dbSNP:748312435
480 480 c, g dbSNP:774326282
483 483 a, g dbSNP:144462453
489 489 a, g dbSNP:749229647
491 491 c, t dbSNP:370445736
493 493 -, acatct dbSNP:768184902
504 504 a, g dbSNP:769640823
510 510 c, t dbSNP:745646581
511 511 a, g dbSNP:150843100
516 516 g, t dbSNP:756909714
523 523 a, g dbSNP:751187988
532 532 a, c dbSNP:777174588
552 552 a, g dbSNP:377395466
556 556 a, g dbSNP:554202436
560 560 a, g dbSNP:766990238
561 561 a, c dbSNP:761180599
562 562 c, g dbSNP:141476053
563 563 c, t dbSNP:767951449
566 566 c, t dbSNP:149269744
578 578 a, g dbSNP:774609275
582 582 a, g dbSNP:374175866
583 583 g, t dbSNP:763080318
596 596 c, t dbSNP:775345858
597 597 a, g dbSNP:769734088
614 614 c, t dbSNP:771548515
622 622 a, c, g dbSNP:758246039
632 632 a, g dbSNP:201435657
641 641 c, t dbSNP:747714515
645 645 a, g dbSNP:778586736
646 646 a, g dbSNP:754513738
653 653 c, t dbSNP:530866311
664 664 a, g dbSNP:746415937
676 676 a, g dbSNP:781762411
685 685 a, g dbSNP:780103335
687 687 c, t dbSNP:145135342
695 695 a, g dbSNP:764296124
706 706 -, cct dbSNP:756515600
714 714 a, c dbSNP:758680325
715 715 a, g dbSNP:752870627
717 717 c, t dbSNP:374400313
718 718 a, g dbSNP:112549790
725 725 a, t dbSNP:759584808
727 727 c, g dbSNP:776616054
733 733 a, g dbSNP:769139831
744 744 a, g dbSNP:747603655
751 751 a, c dbSNP:778115455
773 773 c, t dbSNP:772559347
791 791 a, g dbSNP:748499477
808 808 c, t dbSNP:779190970
817 817 c, t dbSNP:755199180
827 827 c, t dbSNP:41314131
849 849 g, t dbSNP:200350630
864 864 a, g dbSNP:749563408
870 870 c, g dbSNP:143053831
874 874 g, t dbSNP:756275437
877 877 c, t dbSNP:765573996
885 885 a, g dbSNP:781263673
893 893 a, g dbSNP:757288363
902 902 a, g dbSNP:751491407
915 915 g, t dbSNP:764033209
919 919 c, t dbSNP:762814168
920 920 a, g dbSNP:752465402
921 921 g, t dbSNP:764788256
922 922 a, g dbSNP:759170416
925 925 c, t dbSNP:776010315
950 950 c, t dbSNP:765837224
955 955 c, t dbSNP:138457797
967 967 a, t dbSNP:774806924
972 972 a, g dbSNP:769075317
973 973 c, g dbSNP:749602677
984 984 c, g dbSNP:775862469
985 985 c, t dbSNP:769909324
992 992 c, t dbSNP:376340278
1018 1018 c, t dbSNP:777052599
1019 1019 c, t dbSNP:771291436
1026 1026 a, c, g, t dbSNP:143820587
1034 1034 a, g dbSNP:748087382
1037 1037 a, g dbSNP:778903133
1038 1038 c, t dbSNP:768391620
1041 1041 c, t dbSNP:749091380
1043 1043 a, t dbSNP:779753036
1049 1049 a, g dbSNP:371191352
1050 1050 c, g dbSNP:41314137
1053 1053 -, g dbSNP:748518678
1061 1061 c, g dbSNP:750028342
1071 1071 a, g dbSNP:780614862
1075 1075 c, t dbSNP:756758673
1092 1092 c, t dbSNP:753213027
1098 1098 g, t dbSNP:765762629
1111 1111 c, t dbSNP:774005170
1115 1115 a, c dbSNP:754259156
1120 1120 a, g, t dbSNP:377063084
1121 1121 -, t dbSNP:781416108
1125 1125 g, t dbSNP:773549234
1127 1127 c, g dbSNP:772087159
1130 1130 c, g dbSNP:370759645
1134 1134 -, ttc dbSNP:755158874
1145 1145 -, cccaaacc dbSNP:764054289
1153 1153 a, g dbSNP:762343404
1227 1227 c, t dbSNP:1803933
1250 1250 c, t dbSNP:753633516
1251 1251 c, t dbSNP:775326685
1253 1253 c, t dbSNP:1803934
1259 1259 a, g dbSNP:537006596
1282 1282 a, c dbSNP:140430754
1283 1283 c, t dbSNP:772031462
1308 1308 a, g dbSNP:763043445
1320 1320 a, g dbSNP:748228346
1356 1356 -, ag dbSNP:571345715
1362 1362 c, t dbSNP:770031444
1363 1363 c, t dbSNP:755222376
1378 1378 c, t dbSNP:551454985
1401 1401 c, t dbSNP:774585757
1479 1479 -, cttt dbSNP:752745079
1488 1488 a, g dbSNP:745364914
1496 1496 -, a dbSNP:143732744
1496 1496 -, a dbSNP:781608267
1503 1503 c, t dbSNP:554446578
1579 1579 a, t dbSNP:35031864
1603 1603 c, t dbSNP:771366585
1609 1609 g, t dbSNP:1049949
1627 1627 c, t dbSNP:756554801
1634 1634 c, t dbSNP:369791155
1637 1637 c, t dbSNP:778382478
1693 1693 a, g dbSNP:768159745
1734 1734 a, g dbSNP:752228433
1736 1736 a, t dbSNP:778326244
1746 1746 c, t dbSNP:763794596
1847 1847 c, t dbSNP:753488829
2329 2329 a, c, g dbSNP:8639
2329 2329 c, t dbSNP:770124281
2415 2415 -, t dbSNP:201697448
2416 2416 -, t dbSNP:775667584
2438 2438 c, t dbSNP:750243531
2484 2484 c, t dbSNP:776530188
2515 2515 a, c dbSNP:761699451
2522 2522 c, t dbSNP:6832

Target ORF information:

RefSeq Version NM_002355
Organism Homo sapiens (human)
Definition Homo sapiens mannose-6-phosphate receptor (cation dependent) (M6PR), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1-C-(k)DYK
NM_002355

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGTTCCCTT TCTACAGCTG CTGGAGGACT GGACTGCTAC TACTACTCCT GGCTGTGGCA 
GTGAGAGAAT CCTGGCAGAC AGAAGAAAAA ACTTGCGACT TGGTAGGAGA AAAGGGTAAA
GAGTCAGAGA AAGAGTTGGC TCTAGTGAAG AGGCTGAAAC CACTGTTTAA TAAAAGCTTT
GAGAGCACTG TGGGCCAGGG TTCAGACACA TACATCTACA TCTTCAGGGT GTGCCGGGAA
GCTGGCAACC ACACTTCTGG GGCAGGCCTG GTGCAAATCA ACAAAAGTAA TGGGAAGGAG
ACAGTGGTAG GGAGACTCAA CGAGACTCAC ATCTTCAACG GAAGTAATTG GATCATGCTG
ATCTATAAAG GGGGTGATGA ATATGACAAC CACTGTGGCA AGGAGCAGCG TCGTGCAGTG
GTGATGATCT CCTGCAATCG ACACACCCTA GCGGACAATT TTAACCCTGT GTCTGAGGAG
CGTGGCAAAG TCCAAGATTG TTTCTACCTC TTTGAGATGG ATAGCAGCCT GGCCTGTTCA
CCAGAGATCT CCCACCTCAG TGTGGGTTCC ATCTTACTTG TCACGTTTGC ATCACTGGTT
GCTGTTTATG TTGTTGGGGG GTTCCTATAC CAGCGACTGG TAGTGGGAGC CAAAGGAATG
GAGCAGTTTC CCCACTTAGC CTTCTGGCAG GATCTTGGCA ACCTGGTAGC AGATGGCTGT
GACTTTGTCT GCCGTTCTAA ACCTCGAAAT GTGCCTGCAG CATATCGTGG TGTGGGGGAT
GACCAGCTGG GGGAGGAGTC AGAAGAAAGG GATGACCATT TATTACCAAT GTAG

The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.


CloneID OHu19557D
Sequence Information ORF Nucleotide Sequence (Length: 576bp)
Protein sequence
SNP
Vector pcDNA3.1-C-(k)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1-C-(k)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product cation-dependent mannose-6-phosphate receptor isoform 2 precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC341018.1, BU166950.1, BM546062.1, BG750588.1 and AA648974.1. Summary: This gene encodes a member of the P-type lectin family. P-type lectins play a critical role in lysosome function through the specific transport of mannose-6-phosphate-containing acid hydrolases from the Golgi complex to lysosomes. The encoded protein functions as a homodimer and requires divalent cations for ligand binding. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome X. [provided by RefSeq, May 2011]. Transcript Variant: This variant (2) lacks two consecutive exons in the 3' coding region, but maintains the reading frame, compared to variant 1. The encoded isoform (2) is shorter than isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BU166950.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: full length.

1
61
121
181
241
301
361
421
481
541
ATGTTCCCTT TCTACAGCTG CTGGAGGACT GGACTGCTAC TACTACTCCT GGCTGTGGCA 
GTGAGAGAAT CCTGGCAGAC AGAAGAAAAA ACTTGCGACT TGGTAGGAGA AAAGGGTAAA
GAGTCAGAGA AAGAGTTGGC TCTAGTGAAG AGGCTGAAAC CACTGTTTAA TAAAAGCTTT
GAGAGCACTG TGGGCCAGGG TTCAGACACA TACATCTACA TCTTCAGGGT GTGCCGGGAA
GCTGGCAACC ACACTTCTGG GGCAGGCCTG GTGCAAATCA ACAAAAGTAA TGGGAAGGAG
ACAGTGGTAG GGAGACTCAA CGAGACTCAC ATCTTCAACG GAAGTAATTG GATCATGCTG
ATCTATAAAG GGGGTGATGA ATATGACAAC CACTGTGGCA AGGAGCAGCG TCGTGCAGTG
GTGATGATCT CCTGCAATCG ACACACCCTA GCGGATGGCT GTGACTTTGT CTGCCGTTCT
AAACCTCGAA ATGTGCCTGC AGCATATCGT GGTGTGGGGG ATGACCAGCT GGGGGAGGAG
TCAGAAGAAA GGGATGACCA TTTATTACCA ATGTAG
The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.
RefSeqNP_001193953.1
CDS276..851
Misc Feature(1)106..106(+)
Misc Feature(2)243..245(+)
Misc Feature(3)276..848(+)
Exon (1)1..274
Gene:M6PR
Gene Synonym:
Exon (2)275..451
Gene:M6PR
Gene Synonym:
Exon (3)452..618
Gene:M6PR
Gene Synonym:
Exon (4)619..728
Gene:M6PR
Gene Synonym:
Exon (5)729..2308
Gene:M6PR
Gene Synonym:
Translation
Position Chain Variation Link
52 52 a, c dbSNP:753923489
111 111 -, g dbSNP:781043598
117 117 a, c dbSNP:780179610
135 135 c, g dbSNP:765469415
139 139 c, t dbSNP:746937635
179 179 g, t dbSNP:761387333
194 194 c, g dbSNP:546946822
224 224 a, g dbSNP:750736029
228 228 a, g dbSNP:149321629
277 277 -, gtt dbSNP:3217106
278 278 a, g dbSNP:772711346
279 279 c, t dbSNP:771529017
280 280 -, gtt dbSNP:149871778
280 280 -, t dbSNP:756356392
281 281 -, ttg dbSNP:767607953
281 281 c, g dbSNP:763470756
288 288 c, t dbSNP:372848083
293 293 a, c dbSNP:770231911
305 305 g, t dbSNP:746210877
312 312 c, g dbSNP:781538590
313 313 -, gct dbSNP:759574090
314 314 a, g dbSNP:769178316
316 316 c, t dbSNP:777962948
320 320 a, c, g dbSNP:757927047
327 327 a, g dbSNP:368554918
334 334 c, t dbSNP:544775120
336 336 a, g dbSNP:373741481
340 340 c, g dbSNP:186943969
348 348 c, t dbSNP:74060247
350 350 c, g dbSNP:778685998
352 352 a, c, g dbSNP:753587485
368 368 c, t dbSNP:766131528
371 371 c, t dbSNP:142181775
377 377 a, g dbSNP:753001030
378 378 a, g dbSNP:750026229
382 382 a, g dbSNP:371194442
390 390 -, ggtaaag dbSNP:774339933
401 401 a, g dbSNP:776406228
410 410 c, g dbSNP:776041703
411 411 c, t dbSNP:201993451
425 425 -, g dbSNP:766480319
438 438 c, g dbSNP:760032961
439 439 -, tgttta dbSNP:761032764
447 447 a, g dbSNP:367682581
460 460 a, g dbSNP:761090519
462 462 a, c dbSNP:773637333
466 466 c, t dbSNP:772434969
475 475 a, g dbSNP:748312435
480 480 c, g dbSNP:774326282
483 483 a, g dbSNP:144462453
489 489 a, g dbSNP:749229647
491 491 c, t dbSNP:370445736
493 493 -, acatct dbSNP:768184902
504 504 a, g dbSNP:769640823
510 510 c, t dbSNP:745646581
511 511 a, g dbSNP:150843100
516 516 g, t dbSNP:756909714
523 523 a, g dbSNP:751187988
532 532 a, c dbSNP:777174588
552 552 a, g dbSNP:377395466
556 556 a, g dbSNP:554202436
560 560 a, g dbSNP:766990238
561 561 a, c dbSNP:761180599
562 562 c, g dbSNP:141476053
563 563 c, t dbSNP:767951449
566 566 c, t dbSNP:149269744
578 578 a, g dbSNP:774609275
582 582 a, g dbSNP:374175866
583 583 g, t dbSNP:763080318
596 596 c, t dbSNP:775345858
597 597 a, g dbSNP:769734088
614 614 c, t dbSNP:771548515
622 622 a, c, g dbSNP:758246039
632 632 a, g dbSNP:201435657
641 641 c, t dbSNP:747714515
645 645 a, g dbSNP:778586736
646 646 a, g dbSNP:754513738
653 653 c, t dbSNP:530866311
664 664 a, g dbSNP:746415937
676 676 a, g dbSNP:781762411
685 685 a, g dbSNP:780103335
687 687 c, t dbSNP:145135342
695 695 a, g dbSNP:764296124
706 706 -, cct dbSNP:756515600
714 714 a, c dbSNP:758680325
715 715 a, g dbSNP:752870627
717 717 c, t dbSNP:374400313
718 718 a, g dbSNP:112549790
725 725 a, t dbSNP:759584808
727 727 c, g dbSNP:776616054
734 734 c, t dbSNP:376340278
760 760 c, t dbSNP:777052599
761 761 c, t dbSNP:771291436
768 768 a, c, g, t dbSNP:143820587
776 776 a, g dbSNP:748087382
779 779 a, g dbSNP:778903133
780 780 c, t dbSNP:768391620
783 783 c, t dbSNP:749091380
785 785 a, t dbSNP:779753036
791 791 a, g dbSNP:371191352
792 792 c, g dbSNP:41314137
795 795 -, g dbSNP:748518678
803 803 c, g dbSNP:750028342
813 813 a, g dbSNP:780614862
817 817 c, t dbSNP:756758673
834 834 c, t dbSNP:753213027
840 840 g, t dbSNP:765762629
853 853 c, t dbSNP:774005170
857 857 a, c dbSNP:754259156
862 862 a, g, t dbSNP:377063084
863 863 -, t dbSNP:781416108
867 867 g, t dbSNP:773549234
869 869 c, g dbSNP:772087159
872 872 c, g dbSNP:370759645
876 876 -, ttc dbSNP:755158874
887 887 -, cccaaacc dbSNP:764054289
895 895 a, g dbSNP:762343404
969 969 c, t dbSNP:1803933
992 992 c, t dbSNP:753633516
993 993 c, t dbSNP:775326685
995 995 c, t dbSNP:1803934
1001 1001 a, g dbSNP:537006596
1024 1024 a, c dbSNP:140430754
1025 1025 c, t dbSNP:772031462
1050 1050 a, g dbSNP:763043445
1062 1062 a, g dbSNP:748228346
1098 1098 -, ag dbSNP:571345715
1104 1104 c, t dbSNP:770031444
1105 1105 c, t dbSNP:755222376
1120 1120 c, t dbSNP:551454985
1143 1143 c, t dbSNP:774585757
1221 1221 -, cttt dbSNP:752745079
1230 1230 a, g dbSNP:745364914
1238 1238 -, a dbSNP:143732744
1238 1238 -, a dbSNP:781608267
1245 1245 c, t dbSNP:554446578
1321 1321 a, t dbSNP:35031864
1345 1345 c, t dbSNP:771366585
1351 1351 g, t dbSNP:1049949
1369 1369 c, t dbSNP:756554801
1376 1376 c, t dbSNP:369791155
1379 1379 c, t dbSNP:778382478
1435 1435 a, g dbSNP:768159745
1476 1476 a, g dbSNP:752228433
1478 1478 a, t dbSNP:778326244
1488 1488 c, t dbSNP:763794596
1589 1589 c, t dbSNP:753488829
2071 2071 a, c, g dbSNP:8639
2071 2071 c, t dbSNP:770124281
2157 2157 -, t dbSNP:201697448
2158 2158 -, t dbSNP:775667584
2180 2180 c, t dbSNP:750243531
2226 2226 c, t dbSNP:776530188
2257 2257 a, c dbSNP:761699451
2264 2264 c, t dbSNP:6832

Target ORF information:

RefSeq Version NM_001207024
Organism Homo sapiens (human)
Definition Homo sapiens mannose-6-phosphate receptor (cation dependent) (M6PR), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1-C-(k)DYK
NM_001207024

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
ATGTTCCCTT TCTACAGCTG CTGGAGGACT GGACTGCTAC TACTACTCCT GGCTGTGGCA 
GTGAGAGAAT CCTGGCAGAC AGAAGAAAAA ACTTGCGACT TGGTAGGAGA AAAGGGTAAA
GAGTCAGAGA AAGAGTTGGC TCTAGTGAAG AGGCTGAAAC CACTGTTTAA TAAAAGCTTT
GAGAGCACTG TGGGCCAGGG TTCAGACACA TACATCTACA TCTTCAGGGT GTGCCGGGAA
GCTGGCAACC ACACTTCTGG GGCAGGCCTG GTGCAAATCA ACAAAAGTAA TGGGAAGGAG
ACAGTGGTAG GGAGACTCAA CGAGACTCAC ATCTTCAACG GAAGTAATTG GATCATGCTG
ATCTATAAAG GGGGTGATGA ATATGACAAC CACTGTGGCA AGGAGCAGCG TCGTGCAGTG
GTGATGATCT CCTGCAATCG ACACACCCTA GCGGATGGCT GTGACTTTGT CTGCCGTTCT
AAACCTCGAA ATGTGCCTGC AGCATATCGT GGTGTGGGGG ATGACCAGCT GGGGGAGGAG
TCAGAAGAAA GGGATGACCA TTTATTACCA ATGTAG

The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.