The following MAGEA5 gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MAGEA5 gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
||ORF Nucleotide Sequence (Length: 375bp)
||pcDNA3.1+/C-(K)DYK or customized vector
|Tag on pcDNA3.1+/C-(K)DYK
||C terminal DYKDDDDK tags
|ORF Insert Method
||CloneEZ® Seamless cloning technology
||Homo sapiens (human)
||melanoma-associated antigen 5
||REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from BC109187.1, AF274856.3 and
This sequence is a reference standard in the RefSeqGene project.
On Oct 18, 2011 this sequence version replaced gi:58530874.
Summary: This gene is a member of the MAGEA gene family. The
members of this family encode proteins with 50 to 80% sequence
identity to each other. The promoters and first exons of the MAGEA
genes show considerable variability, suggesting that the existence
of this gene family enables the same function to be expressed under
different transcriptional controls. The MAGEA genes are clustered
at chromosomal location Xq28. They have been implicated in some
hereditary disorders, such as dyskeratosis congenita. This MAGEA
gene encodes a protein that is C-terminally truncated compared to
other family members, and this gene can be alternatively
interpreted to be a pseudogene. The protein is represented in this
Gene record in accordance with the assumed protein-coding status
defined in the literature. Read-through transcription exists
between this gene and the upstream melanoma antigen family A, 10
(MAGEA10) gene. [provided by RefSeq, Oct 2011].
Sequence Note: This RefSeq record was created from transcript and
genomic sequence data to make the sequence consistent with the
reference genome assembly. The genomic coordinates used for the
transcript record were based on transcript alignments.
Transcript exon combination :: BC109187.1 [ECO:0000332]
RNAseq introns :: mixed/partial sample support
COMPLETENESS: complete on the 3' end.