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MAGEA6 cDNA ORF clone, Homo sapiens (human)

Gene Symbol MAGEA6
Entrez Gene ID 4105
Full Name melanoma antigen family A6
Synonyms CT1.6, MAGE-3b, MAGE3B, MAGE6
General protein information
Preferred Names
melanoma-associated antigen 6
Names
melanoma-associated antigen 6
MAGE-6 antigen
MAGE3B antigen
cancer/testis antigen 1.6
cancer/testis antigen family 1, member 6
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

X

Xq28

Summary This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]. lac of sum
Disorder MIM:

300176

Disorder Html:





The following MAGEA6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MAGEA6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu07419 XM_011531162 PREDICTED: Homo sapiens melanoma antigen family A6 (MAGEA6), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$139.30
$199.00
OHu07419 NM_005363 Homo sapiens melanoma antigen family A6 (MAGEA6), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$139.30
$199.00
OHu07419 NM_175868 Homo sapiens melanoma antigen family A6 (MAGEA6), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$139.30
$199.00

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu07419
Accession Version XM_011531162.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 945bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product melanoma-associated antigen 6 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_011681.17) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGCCTCTTG AGCAGAGGAG TCAGCACTGC AAGCCTGAAG AAGGCCTTGA GGCCCGAGGA 
GAGGCCCTGG GCCTGGTGGG TGCGCAGGCT CCTGCTACTG AGGAGCAGGA GGCTGCCTCC
TCCTCTTCTA CTCTAGTTGA AGTCACCCTG GGGGAGGTGC CTGCTGCCGA GTCACCAGAT
CCTCCCCAGA GTCCTCAGGG AGCCTCCAGC CTCCCCACTA CCATGAACTA CCCTCTCTGG
AGCCAATCCT ATGAGGACTC CAGCAACCAA GAAGAGGAGG GGCCAAGCAC CTTCCCTGAC
CTGGAGTCTG AGTTCCAAGC AGCACTCAGT AGGAAGGTGG CCAAGTTGGT TCATTTTCTG
CTCCTCAAGT ATCGAGCCAG GGAGCCGGTC ACAAAGGCAG AAATGCTGGG GAGTGTCGTC
GGAAATTGGC AGTACTTCTT TCCTGTGATC TTCAGCAAAG CTTCCGATTC CTTGCAGCTG
GTCTTTGGCA TCGAGCTGAT GGAAGTGGAC CCCATCGGCC ACGTGTACAT CTTTGCCACC
TGCCTGGGCC TCTCCTACGA TGGCCTGCTG GGTGACAATC AGATCATGCC CAAGACAGGC
TTCCTGATAA TCATCCTGGC CATAATCGCA AAAGAGGGCG ACTGTGCCCC TGAGGAGAAA
ATCTGGGAGG AGCTGAGTGT GTTAGAGGTG TTTGAGGGGA GGGAAGACAG TATCTTCGGG
GATCCCAAGA AGCTGCTCAC CCAATATTTC GTGCAGGAAA ACTACCTGGA GTACCGGCAG
GTCCCCGGCA GTGATCCTGC ATGCTATGAG TTCCTGTGGG GTCCAAGGGC CCTCATTGAA
ACCAGCTATG TGAAAGTCCT GCACCATATG GTAAAGATCA GTGGAGGACC TCGCATTTCC
TACCCACTCC TGCATGAGTG GGCTTTGAGA GAGGGGGAAG AGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqXP_011529464.1
CDS366..1310
Misc Feature(1)372..659(+)
Misc Feature(2)711..1223(+)
Translation
Position Chain Variation Link
256 256 c, g dbSNP:5925210
264 264 a, c dbSNP:5970361
800 800 c, t dbSNP:7057497
1175 1175 a, g dbSNP:12846936
1359 1359 g, t dbSNP:116616525
1684 1684 a, t dbSNP:79550623

Target ORF information:

RefSeq Version XM_011531162
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens melanoma antigen family A6 (MAGEA6), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011531162

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGCCTCTTG AGCAGAGGAG TCAGCACTGC AAGCCTGAAG AAGGCCTTGA GGCCCGAGGA 
GAGGCCCTGG GCCTGGTGGG TGCGCAGGCT CCTGCTACTG AGGAGCAGGA GGCTGCCTCC
TCCTCTTCTA CTCTAGTTGA AGTCACCCTG GGGGAGGTGC CTGCTGCCGA GTCACCAGAT
CCTCCCCAGA GTCCTCAGGG AGCCTCCAGC CTCCCCACTA CCATGAACTA CCCTCTCTGG
AGCCAATCCT ATGAGGACTC CAGCAACCAA GAAGAGGAGG GGCCAAGCAC CTTCCCTGAC
CTGGAGTCTG AGTTCCAAGC AGCACTCAGT AGGAAGGTGG CCAAGTTGGT TCATTTTCTG
CTCCTCAAGT ATCGAGCCAG GGAGCCGGTC ACAAAGGCAG AAATGCTGGG GAGTGTCGTC
GGAAATTGGC AGTACTTCTT TCCTGTGATC TTCAGCAAAG CTTCCGATTC CTTGCAGCTG
GTCTTTGGCA TCGAGCTGAT GGAAGTGGAC CCCATCGGCC ACGTGTACAT CTTTGCCACC
TGCCTGGGCC TCTCCTACGA TGGCCTGCTG GGTGACAATC AGATCATGCC CAAGACAGGC
TTCCTGATAA TCATCCTGGC CATAATCGCA AAAGAGGGCG ACTGTGCCCC TGAGGAGAAA
ATCTGGGAGG AGCTGAGTGT GTTAGAGGTG TTTGAGGGGA GGGAAGACAG TATCTTCGGG
GATCCCAAGA AGCTGCTCAC CCAATATTTC GTGCAGGAAA ACTACCTGGA GTACCGGCAG
GTCCCCGGCA GTGATCCTGC ATGCTATGAG TTCCTGTGGG GTCCAAGGGC CCTCATTGAA
ACCAGCTATG TGAAAGTCCT GCACCATATG GTAAAGATCA GTGGAGGACC TCGCATTTCC
TACCCACTCC TGCATGAGTG GGCTTTGAGA GAGGGGGAAG AGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu07419
Accession Version NM_005363.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 945bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product melanoma-associated antigen 6
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC041599.1 and BM843807.1. On Mar 18, 2003 this sequence version replaced gi:4885468. Summary: This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]. Transcript Variant: This variant (1) differs in the 5' UTR, compared to variant 2. Variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK289437.1, BC067731.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2148093, SAMEA2148874 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGCCTCTTG AGCAGAGGAG TCAGCACTGC AAGCCTGAAG AAGGCCTTGA GGCCCGAGGA 
GAGGCCCTGG GCCTGGTGGG TGCGCAGGCT CCTGCTACTG AGGAGCAGGA GGCTGCCTCC
TCCTCTTCTA CTCTAGTTGA AGTCACCCTG GGGGAGGTGC CTGCTGCCGA GTCACCAGAT
CCTCCCCAGA GTCCTCAGGG AGCCTCCAGC CTCCCCACTA CCATGAACTA CCCTCTCTGG
AGCCAATCCT ATGAGGACTC CAGCAACCAA GAAGAGGAGG GGCCAAGCAC CTTCCCTGAC
CTGGAGTCTG AGTTCCAAGC AGCACTCAGT AGGAAGGTGG CCAAGTTGGT TCATTTTCTG
CTCCTCAAGT ATCGAGCCAG GGAGCCGGTC ACAAAGGCAG AAATGCTGGG GAGTGTCGTC
GGAAATTGGC AGTACTTCTT TCCTGTGATC TTCAGCAAAG CTTCCGATTC CTTGCAGCTG
GTCTTTGGCA TCGAGCTGAT GGAAGTGGAC CCCATCGGCC ACGTGTACAT CTTTGCCACC
TGCCTGGGCC TCTCCTACGA TGGCCTGCTG GGTGACAATC AGATCATGCC CAAGACAGGC
TTCCTGATAA TCATCCTGGC CATAATCGCA AAAGAGGGCG ACTGTGCCCC TGAGGAGAAA
ATCTGGGAGG AGCTGAGTGT GTTAGAGGTG TTTGAGGGGA GGGAAGACAG TATCTTCGGG
GATCCCAAGA AGCTGCTCAC CCAATATTTC GTGCAGGAAA ACTACCTGGA GTACCGGCAG
GTCCCCGGCA GTGATCCTGC ATGCTATGAG TTCCTGTGGG GTCCAAGGGC CCTCATTGAA
ACCAGCTATG TGAAAGTCCT GCACCATATG GTAAAGATCA GTGGAGGACC TCGCATTTCC
TACCCACTCC TGCATGAGTG GGCTTTGAGA GAGGGGGAAG AGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqNP_005354.1
CDS195..1139
Misc Feature(1)81..83(+)
Misc Feature(2)201..488(+)
Misc Feature(3)540..1052(+)
Exon (1)1..63
Gene:MAGEA6
Gene Synonym:
Exon (2)64..129
Gene:MAGEA6
Gene Synonym:
Exon (3)130..1698
Gene:MAGEA6
Gene Synonym:
Translation
Position Chain Variation Link
85 85 c, g dbSNP:5925210
93 93 a, c dbSNP:5970361
629 629 c, t dbSNP:7057497
1004 1004 a, g dbSNP:12846936
1188 1188 g, t dbSNP:116616525
1513 1513 a, t dbSNP:79550623

Target ORF information:

RefSeq Version NM_005363
Organism Homo sapiens (human)
Definition Homo sapiens melanoma antigen family A6 (MAGEA6), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_005363

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGCCTCTTG AGCAGAGGAG TCAGCACTGC AAGCCTGAAG AAGGCCTTGA GGCCCGAGGA 
GAGGCCCTGG GCCTGGTGGG TGCGCAGGCT CCTGCTACTG AGGAGCAGGA GGCTGCCTCC
TCCTCTTCTA CTCTAGTTGA AGTCACCCTG GGGGAGGTGC CTGCTGCCGA GTCACCAGAT
CCTCCCCAGA GTCCTCAGGG AGCCTCCAGC CTCCCCACTA CCATGAACTA CCCTCTCTGG
AGCCAATCCT ATGAGGACTC CAGCAACCAA GAAGAGGAGG GGCCAAGCAC CTTCCCTGAC
CTGGAGTCTG AGTTCCAAGC AGCACTCAGT AGGAAGGTGG CCAAGTTGGT TCATTTTCTG
CTCCTCAAGT ATCGAGCCAG GGAGCCGGTC ACAAAGGCAG AAATGCTGGG GAGTGTCGTC
GGAAATTGGC AGTACTTCTT TCCTGTGATC TTCAGCAAAG CTTCCGATTC CTTGCAGCTG
GTCTTTGGCA TCGAGCTGAT GGAAGTGGAC CCCATCGGCC ACGTGTACAT CTTTGCCACC
TGCCTGGGCC TCTCCTACGA TGGCCTGCTG GGTGACAATC AGATCATGCC CAAGACAGGC
TTCCTGATAA TCATCCTGGC CATAATCGCA AAAGAGGGCG ACTGTGCCCC TGAGGAGAAA
ATCTGGGAGG AGCTGAGTGT GTTAGAGGTG TTTGAGGGGA GGGAAGACAG TATCTTCGGG
GATCCCAAGA AGCTGCTCAC CCAATATTTC GTGCAGGAAA ACTACCTGGA GTACCGGCAG
GTCCCCGGCA GTGATCCTGC ATGCTATGAG TTCCTGTGGG GTCCAAGGGC CCTCATTGAA
ACCAGCTATG TGAAAGTCCT GCACCATATG GTAAAGATCA GTGGAGGACC TCGCATTTCC
TACCCACTCC TGCATGAGTG GGCTTTGAGA GAGGGGGAAG AGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu07419
Accession Version NM_175868.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 945bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product melanoma-associated antigen 6
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC041599.1 and BM843807.1. Summary: This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]. Transcript Variant: This variant (2) represents the longer transcript. Variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BM843807.1, HY015473.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142680, SAMEA2158188 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGCCTCTTG AGCAGAGGAG TCAGCACTGC AAGCCTGAAG AAGGCCTTGA GGCCCGAGGA 
GAGGCCCTGG GCCTGGTGGG TGCGCAGGCT CCTGCTACTG AGGAGCAGGA GGCTGCCTCC
TCCTCTTCTA CTCTAGTTGA AGTCACCCTG GGGGAGGTGC CTGCTGCCGA GTCACCAGAT
CCTCCCCAGA GTCCTCAGGG AGCCTCCAGC CTCCCCACTA CCATGAACTA CCCTCTCTGG
AGCCAATCCT ATGAGGACTC CAGCAACCAA GAAGAGGAGG GGCCAAGCAC CTTCCCTGAC
CTGGAGTCTG AGTTCCAAGC AGCACTCAGT AGGAAGGTGG CCAAGTTGGT TCATTTTCTG
CTCCTCAAGT ATCGAGCCAG GGAGCCGGTC ACAAAGGCAG AAATGCTGGG GAGTGTCGTC
GGAAATTGGC AGTACTTCTT TCCTGTGATC TTCAGCAAAG CTTCCGATTC CTTGCAGCTG
GTCTTTGGCA TCGAGCTGAT GGAAGTGGAC CCCATCGGCC ACGTGTACAT CTTTGCCACC
TGCCTGGGCC TCTCCTACGA TGGCCTGCTG GGTGACAATC AGATCATGCC CAAGACAGGC
TTCCTGATAA TCATCCTGGC CATAATCGCA AAAGAGGGCG ACTGTGCCCC TGAGGAGAAA
ATCTGGGAGG AGCTGAGTGT GTTAGAGGTG TTTGAGGGGA GGGAAGACAG TATCTTCGGG
GATCCCAAGA AGCTGCTCAC CCAATATTTC GTGCAGGAAA ACTACCTGGA GTACCGGCAG
GTCCCCGGCA GTGATCCTGC ATGCTATGAG TTCCTGTGGG GTCCAAGGGC CCTCATTGAA
ACCAGCTATG TGAAAGTCCT GCACCATATG GTAAAGATCA GTGGAGGACC TCGCATTTCC
TACCCACTCC TGCATGAGTG GGCTTTGAGA GAGGGGGAAG AGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqNP_787064.1
CDS259..1203
Misc Feature(1)145..147(+)
Misc Feature(2)265..552(+)
Misc Feature(3)604..1116(+)
Exon (1)1..63
Gene:MAGEA6
Gene Synonym:
Exon (2)64..193
Gene:MAGEA6
Gene Synonym:
Exon (3)194..1762
Gene:MAGEA6
Gene Synonym:
Translation
Position Chain Variation Link
82 82 c, t dbSNP:5970360
82 82 c, t dbSNP:200648457
149 149 c, g dbSNP:5925210
157 157 a, c dbSNP:5970361
693 693 c, t dbSNP:7057497
1068 1068 a, g dbSNP:12846936
1252 1252 g, t dbSNP:116616525
1577 1577 a, t dbSNP:79550623

Target ORF information:

RefSeq Version NM_175868
Organism Homo sapiens (human)
Definition Homo sapiens melanoma antigen family A6 (MAGEA6), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_175868

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGCCTCTTG AGCAGAGGAG TCAGCACTGC AAGCCTGAAG AAGGCCTTGA GGCCCGAGGA 
GAGGCCCTGG GCCTGGTGGG TGCGCAGGCT CCTGCTACTG AGGAGCAGGA GGCTGCCTCC
TCCTCTTCTA CTCTAGTTGA AGTCACCCTG GGGGAGGTGC CTGCTGCCGA GTCACCAGAT
CCTCCCCAGA GTCCTCAGGG AGCCTCCAGC CTCCCCACTA CCATGAACTA CCCTCTCTGG
AGCCAATCCT ATGAGGACTC CAGCAACCAA GAAGAGGAGG GGCCAAGCAC CTTCCCTGAC
CTGGAGTCTG AGTTCCAAGC AGCACTCAGT AGGAAGGTGG CCAAGTTGGT TCATTTTCTG
CTCCTCAAGT ATCGAGCCAG GGAGCCGGTC ACAAAGGCAG AAATGCTGGG GAGTGTCGTC
GGAAATTGGC AGTACTTCTT TCCTGTGATC TTCAGCAAAG CTTCCGATTC CTTGCAGCTG
GTCTTTGGCA TCGAGCTGAT GGAAGTGGAC CCCATCGGCC ACGTGTACAT CTTTGCCACC
TGCCTGGGCC TCTCCTACGA TGGCCTGCTG GGTGACAATC AGATCATGCC CAAGACAGGC
TTCCTGATAA TCATCCTGGC CATAATCGCA AAAGAGGGCG ACTGTGCCCC TGAGGAGAAA
ATCTGGGAGG AGCTGAGTGT GTTAGAGGTG TTTGAGGGGA GGGAAGACAG TATCTTCGGG
GATCCCAAGA AGCTGCTCAC CCAATATTTC GTGCAGGAAA ACTACCTGGA GTACCGGCAG
GTCCCCGGCA GTGATCCTGC ATGCTATGAG TTCCTGTGGG GTCCAAGGGC CCTCATTGAA
ACCAGCTATG TGAAAGTCCT GCACCATATG GTAAAGATCA GTGGAGGACC TCGCATTTCC
TACCCACTCC TGCATGAGTG GGCTTTGAGA GAGGGGGAAG AGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

 
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