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MAGEA10 cDNA ORF clone, Homo sapiens (human)

Gene Symbol MAGEA10
Entrez Gene ID 4109
Full Name melanoma antigen family A10
Synonyms CT1.10, MAGE10
General protein information
Preferred Names
melanoma-associated antigen 10
Names
melanoma-associated antigen 10
MAGE-10 antigen
cancer/testis antigen 1.10
cancer/testis antigen family 1, member 10
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

X

Xq28

Summary This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream melanoma antigen family A, 5 (MAGEA5) gene.[provided by RefSeq, Oct 2011]. lac of sum
Disorder MIM:

300343


mRNA and Protein(s)

mRNA Protein Name
NM_001011543 NP_001011543 melanoma-associated antigen 10
NM_021048 NP_066386 melanoma-associated antigen 10
NM_001251828 NP_001238757 melanoma-associated antigen 10


Homo sapiens (human) MAGEA10 NP_001011543.2
Pan troglodytes (chimpanzee) MAGEA10 XP_521312.3
Macaca mulatta (Rhesus monkey) LOC711149 XP_001099898.2
Bos taurus (cattle) LOC508073 XP_005227624.1
Mus musculus (house mouse) Magea10 NP_001078975.1
Rattus norvegicus (Norway rat) Magea10 XP_006229580.1

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following MAGEA10 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MAGEA10 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu10659
NM_001011543 Homo sapiens melanoma antigen family A10 (MAGEA10), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$159.50-$223.30
$319.00
OHu10659
NM_021048 Homo sapiens melanoma antigen family A10 (MAGEA10), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$159.50-$223.30
$319.00
OHu10659
NM_001251828 Homo sapiens melanoma antigen family A10 (MAGEA10), transcript variant 3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$159.50-$223.30
$319.00
Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
5 or more Clone 50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu10659
Clone ID Related Accession (Same CDS sequence) NM_001011543 , NM_001251828 , NM_021048
Accession Version NM_001011543.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1110bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product melanoma-associated antigen 10
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK314161.1, CB158974.1, AC116666.2, BC004105.2 and BQ026281.1. On Oct 18, 2011 this sequence version replaced gi:58530862. Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2 and 3 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BM458898.1, BU167137.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142853, SAMEA2148093 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
ATGCCTCGAG CTCCAAAGCG TCAGCGCTGC ATGCCTGAAG AAGATCTTCA ATCCCAAAGT 
GAGACACAGG GCCTCGAGGG TGCACAGGCT CCCCTGGCTG TGGAGGAGGA TGCTTCATCA
TCCACTTCCA CCAGCTCCTC TTTTCCATCC TCTTTTCCCT CCTCCTCCTC TTCCTCCTCC
TCCTCCTGCT ATCCTCTAAT ACCAAGCACC CCAGAGGAGG TTTCTGCTGA TGATGAGACA
CCAAATCCTC CCCAGAGTGC TCAGATAGCC TGCTCCTCCC CCTCGGTCGT TGCTTCCCTT
CCATTAGATC AATCTGATGA GGGCTCCAGC AGCCAAAAGG AGGAGAGTCC AAGCACCCTA
CAGGTCCTGC CAGACAGTGA GTCTTTACCC AGAAGTGAGA TAGATGAAAA GGTGACTGAT
TTGGTGCAGT TTCTGCTCTT CAAGTATCAA ATGAAGGAGC CGATCACAAA GGCAGAAATA
CTGGAGAGTG TCATAAGAAA TTATGAAGAC CACTTCCCTT TGTTGTTTAG TGAAGCCTCC
GAGTGCATGC TGCTGGTCTT TGGCATTGAT GTAAAGGAAG TGGATCCCAC TGGCCACTCC
TTTGTCCTTG TCACCTCCCT GGGCCTCACC TATGATGGGA TGCTGAGTGA TGTCCAGAGC
ATGCCCAAGA CTGGCATTCT CATACTTATC CTAAGCATAA TCTTCATAGA GGGCTACTGC
ACCCCTGAGG AGGTCATCTG GGAAGCACTG AATATGATGG GGCTGTATGA TGGGATGGAG
CACCTCATTT ATGGGGAGCC CAGGAAGCTG CTCACCCAAG ATTGGGTGCA GGAAAACTAC
CTGGAGTACC GGCAGGTGCC TGGCAGTGAT CCTGCACGGT ATGAGTTTCT GTGGGGTCCA
AGGGCTCATG CTGAAATTAG GAAGATGAGT CTCCTGAAAT TTTTGGCCAA GGTAAATGGG
AGTGATCCAA GATCCTTCCC ACTGTGGTAT GAGGAGGCTT TGAAAGATGA GGAAGAGAGA
GCCCAGGACA GAATTGCCAC CACAGATGAT ACTACTGCCA TGGCCAGTGC AAGTTCTAGC
GCTACAGGTA GCTTCTCCTA CCCTGAATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001011543.2
CDS434..1543
Misc Feature(1)224..226(+)
Misc Feature(2)440..793(+)
Misc Feature(3)854..1366(+)
Exon (1)1..104
Gene:MAGEA10
Gene Synonym:
Exon (2)105..203
Gene:MAGEA10
Gene Synonym:
Exon (3)204..294
Gene:MAGEA10
Gene Synonym:
Exon (4)295..368
Gene:MAGEA10
Gene Synonym:
Exon (5)369..2744
Gene:MAGEA10
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001011543
Organism Homo sapiens (human)
Definition Homo sapiens melanoma antigen family A10 (MAGEA10), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001011543

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
ATGCCTCGAG CTCCAAAGCG TCAGCGCTGC ATGCCTGAAG AAGATCTTCA ATCCCAAAGT 
GAGACACAGG GCCTCGAGGG TGCACAGGCT CCCCTGGCTG TGGAGGAGGA TGCTTCATCA
TCCACTTCCA CCAGCTCCTC TTTTCCATCC TCTTTTCCCT CCTCCTCCTC TTCCTCCTCC
TCCTCCTGCT ATCCTCTAAT ACCAAGCACC CCAGAGGAGG TTTCTGCTGA TGATGAGACA
CCAAATCCTC CCCAGAGTGC TCAGATAGCC TGCTCCTCCC CCTCGGTCGT TGCTTCCCTT
CCATTAGATC AATCTGATGA GGGCTCCAGC AGCCAAAAGG AGGAGAGTCC AAGCACCCTA
CAGGTCCTGC CAGACAGTGA GTCTTTACCC AGAAGTGAGA TAGATGAAAA GGTGACTGAT
TTGGTGCAGT TTCTGCTCTT CAAGTATCAA ATGAAGGAGC CGATCACAAA GGCAGAAATA
CTGGAGAGTG TCATAAGAAA TTATGAAGAC CACTTCCCTT TGTTGTTTAG TGAAGCCTCC
GAGTGCATGC TGCTGGTCTT TGGCATTGAT GTAAAGGAAG TGGATCCCAC TGGCCACTCC
TTTGTCCTTG TCACCTCCCT GGGCCTCACC TATGATGGGA TGCTGAGTGA TGTCCAGAGC
ATGCCCAAGA CTGGCATTCT CATACTTATC CTAAGCATAA TCTTCATAGA GGGCTACTGC
ACCCCTGAGG AGGTCATCTG GGAAGCACTG AATATGATGG GGCTGTATGA TGGGATGGAG
CACCTCATTT ATGGGGAGCC CAGGAAGCTG CTCACCCAAG ATTGGGTGCA GGAAAACTAC
CTGGAGTACC GGCAGGTGCC TGGCAGTGAT CCTGCACGGT ATGAGTTTCT GTGGGGTCCA
AGGGCTCATG CTGAAATTAG GAAGATGAGT CTCCTGAAAT TTTTGGCCAA GGTAAATGGG
AGTGATCCAA GATCCTTCCC ACTGTGGTAT GAGGAGGCTT TGAAAGATGA GGAAGAGAGA
GCCCAGGACA GAATTGCCAC CACAGATGAT ACTACTGCCA TGGCCAGTGC AAGTTCTAGC
GCTACAGGTA GCTTCTCCTA CCCTGAATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu10659
Clone ID Related Accession (Same CDS sequence) NM_001011543 , NM_001251828 , NM_021048
Accession Version NM_021048.4 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1110bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product melanoma-associated antigen 10
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK314161.1, AC116666.2, BC004105.2 and BQ026281.1. On Oct 18, 2011 this sequence version replaced gi:29029613. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK314161.1, BC004105.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2142853 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
ATGCCTCGAG CTCCAAAGCG TCAGCGCTGC ATGCCTGAAG AAGATCTTCA ATCCCAAAGT 
GAGACACAGG GCCTCGAGGG TGCACAGGCT CCCCTGGCTG TGGAGGAGGA TGCTTCATCA
TCCACTTCCA CCAGCTCCTC TTTTCCATCC TCTTTTCCCT CCTCCTCCTC TTCCTCCTCC
TCCTCCTGCT ATCCTCTAAT ACCAAGCACC CCAGAGGAGG TTTCTGCTGA TGATGAGACA
CCAAATCCTC CCCAGAGTGC TCAGATAGCC TGCTCCTCCC CCTCGGTCGT TGCTTCCCTT
CCATTAGATC AATCTGATGA GGGCTCCAGC AGCCAAAAGG AGGAGAGTCC AAGCACCCTA
CAGGTCCTGC CAGACAGTGA GTCTTTACCC AGAAGTGAGA TAGATGAAAA GGTGACTGAT
TTGGTGCAGT TTCTGCTCTT CAAGTATCAA ATGAAGGAGC CGATCACAAA GGCAGAAATA
CTGGAGAGTG TCATAAGAAA TTATGAAGAC CACTTCCCTT TGTTGTTTAG TGAAGCCTCC
GAGTGCATGC TGCTGGTCTT TGGCATTGAT GTAAAGGAAG TGGATCCCAC TGGCCACTCC
TTTGTCCTTG TCACCTCCCT GGGCCTCACC TATGATGGGA TGCTGAGTGA TGTCCAGAGC
ATGCCCAAGA CTGGCATTCT CATACTTATC CTAAGCATAA TCTTCATAGA GGGCTACTGC
ACCCCTGAGG AGGTCATCTG GGAAGCACTG AATATGATGG GGCTGTATGA TGGGATGGAG
CACCTCATTT ATGGGGAGCC CAGGAAGCTG CTCACCCAAG ATTGGGTGCA GGAAAACTAC
CTGGAGTACC GGCAGGTGCC TGGCAGTGAT CCTGCACGGT ATGAGTTTCT GTGGGGTCCA
AGGGCTCATG CTGAAATTAG GAAGATGAGT CTCCTGAAAT TTTTGGCCAA GGTAAATGGG
AGTGATCCAA GATCCTTCCC ACTGTGGTAT GAGGAGGCTT TGAAAGATGA GGAAGAGAGA
GCCCAGGACA GAATTGCCAC CACAGATGAT ACTACTGCCA TGGCCAGTGC AAGTTCTAGC
GCTACAGGTA GCTTCTCCTA CCCTGAATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_066386.2
CDS343..1452
Misc Feature(1)190..192(+)
Misc Feature(2)349..702(+)
Misc Feature(3)763..1275(+)
Exon (1)1..104
Gene:MAGEA10
Gene Synonym:
Exon (2)105..203
Gene:MAGEA10
Gene Synonym:
Exon (3)204..277
Gene:MAGEA10
Gene Synonym:
Exon (4)278..2653
Gene:MAGEA10
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_021048
Organism Homo sapiens (human)
Definition Homo sapiens melanoma antigen family A10 (MAGEA10), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_021048

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
ATGCCTCGAG CTCCAAAGCG TCAGCGCTGC ATGCCTGAAG AAGATCTTCA ATCCCAAAGT 
GAGACACAGG GCCTCGAGGG TGCACAGGCT CCCCTGGCTG TGGAGGAGGA TGCTTCATCA
TCCACTTCCA CCAGCTCCTC TTTTCCATCC TCTTTTCCCT CCTCCTCCTC TTCCTCCTCC
TCCTCCTGCT ATCCTCTAAT ACCAAGCACC CCAGAGGAGG TTTCTGCTGA TGATGAGACA
CCAAATCCTC CCCAGAGTGC TCAGATAGCC TGCTCCTCCC CCTCGGTCGT TGCTTCCCTT
CCATTAGATC AATCTGATGA GGGCTCCAGC AGCCAAAAGG AGGAGAGTCC AAGCACCCTA
CAGGTCCTGC CAGACAGTGA GTCTTTACCC AGAAGTGAGA TAGATGAAAA GGTGACTGAT
TTGGTGCAGT TTCTGCTCTT CAAGTATCAA ATGAAGGAGC CGATCACAAA GGCAGAAATA
CTGGAGAGTG TCATAAGAAA TTATGAAGAC CACTTCCCTT TGTTGTTTAG TGAAGCCTCC
GAGTGCATGC TGCTGGTCTT TGGCATTGAT GTAAAGGAAG TGGATCCCAC TGGCCACTCC
TTTGTCCTTG TCACCTCCCT GGGCCTCACC TATGATGGGA TGCTGAGTGA TGTCCAGAGC
ATGCCCAAGA CTGGCATTCT CATACTTATC CTAAGCATAA TCTTCATAGA GGGCTACTGC
ACCCCTGAGG AGGTCATCTG GGAAGCACTG AATATGATGG GGCTGTATGA TGGGATGGAG
CACCTCATTT ATGGGGAGCC CAGGAAGCTG CTCACCCAAG ATTGGGTGCA GGAAAACTAC
CTGGAGTACC GGCAGGTGCC TGGCAGTGAT CCTGCACGGT ATGAGTTTCT GTGGGGTCCA
AGGGCTCATG CTGAAATTAG GAAGATGAGT CTCCTGAAAT TTTTGGCCAA GGTAAATGGG
AGTGATCCAA GATCCTTCCC ACTGTGGTAT GAGGAGGCTT TGAAAGATGA GGAAGAGAGA
GCCCAGGACA GAATTGCCAC CACAGATGAT ACTACTGCCA TGGCCAGTGC AAGTTCTAGC
GCTACAGGTA GCTTCTCCTA CCCTGAATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu10659
Clone ID Related Accession (Same CDS sequence) NM_001011543 , NM_001251828 , NM_021048
Accession Version NM_001251828.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1110bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product melanoma-associated antigen 10
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK314161.1, DA827990.1, AC116666.2, BC004105.2 and BQ026281.1. Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: DA827990.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142853, SAMEA2148093 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
ATGCCTCGAG CTCCAAAGCG TCAGCGCTGC ATGCCTGAAG AAGATCTTCA ATCCCAAAGT 
GAGACACAGG GCCTCGAGGG TGCACAGGCT CCCCTGGCTG TGGAGGAGGA TGCTTCATCA
TCCACTTCCA CCAGCTCCTC TTTTCCATCC TCTTTTCCCT CCTCCTCCTC TTCCTCCTCC
TCCTCCTGCT ATCCTCTAAT ACCAAGCACC CCAGAGGAGG TTTCTGCTGA TGATGAGACA
CCAAATCCTC CCCAGAGTGC TCAGATAGCC TGCTCCTCCC CCTCGGTCGT TGCTTCCCTT
CCATTAGATC AATCTGATGA GGGCTCCAGC AGCCAAAAGG AGGAGAGTCC AAGCACCCTA
CAGGTCCTGC CAGACAGTGA GTCTTTACCC AGAAGTGAGA TAGATGAAAA GGTGACTGAT
TTGGTGCAGT TTCTGCTCTT CAAGTATCAA ATGAAGGAGC CGATCACAAA GGCAGAAATA
CTGGAGAGTG TCATAAGAAA TTATGAAGAC CACTTCCCTT TGTTGTTTAG TGAAGCCTCC
GAGTGCATGC TGCTGGTCTT TGGCATTGAT GTAAAGGAAG TGGATCCCAC TGGCCACTCC
TTTGTCCTTG TCACCTCCCT GGGCCTCACC TATGATGGGA TGCTGAGTGA TGTCCAGAGC
ATGCCCAAGA CTGGCATTCT CATACTTATC CTAAGCATAA TCTTCATAGA GGGCTACTGC
ACCCCTGAGG AGGTCATCTG GGAAGCACTG AATATGATGG GGCTGTATGA TGGGATGGAG
CACCTCATTT ATGGGGAGCC CAGGAAGCTG CTCACCCAAG ATTGGGTGCA GGAAAACTAC
CTGGAGTACC GGCAGGTGCC TGGCAGTGAT CCTGCACGGT ATGAGTTTCT GTGGGGTCCA
AGGGCTCATG CTGAAATTAG GAAGATGAGT CTCCTGAAAT TTTTGGCCAA GGTAAATGGG
AGTGATCCAA GATCCTTCCC ACTGTGGTAT GAGGAGGCTT TGAAAGATGA GGAAGAGAGA
GCCCAGGACA GAATTGCCAC CACAGATGAT ACTACTGCCA TGGCCAGTGC AAGTTCTAGC
GCTACAGGTA GCTTCTCCTA CCCTGAATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001238757.1
CDS362..1471
Misc Feature(1)110..112(+)
Misc Feature(2)368..721(+)
Misc Feature(3)782..1294(+)
Exon (1)1..104
Gene:MAGEA10
Gene Synonym:
Exon (2)105..203
Gene:MAGEA10
Gene Synonym:
Exon (3)204..222
Gene:MAGEA10
Gene Synonym:
Exon (4)223..296
Gene:MAGEA10
Gene Synonym:
Exon (5)297..2672
Gene:MAGEA10
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001251828
Organism Homo sapiens (human)
Definition Homo sapiens melanoma antigen family A10 (MAGEA10), transcript variant 3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001251828

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
ATGCCTCGAG CTCCAAAGCG TCAGCGCTGC ATGCCTGAAG AAGATCTTCA ATCCCAAAGT 
GAGACACAGG GCCTCGAGGG TGCACAGGCT CCCCTGGCTG TGGAGGAGGA TGCTTCATCA
TCCACTTCCA CCAGCTCCTC TTTTCCATCC TCTTTTCCCT CCTCCTCCTC TTCCTCCTCC
TCCTCCTGCT ATCCTCTAAT ACCAAGCACC CCAGAGGAGG TTTCTGCTGA TGATGAGACA
CCAAATCCTC CCCAGAGTGC TCAGATAGCC TGCTCCTCCC CCTCGGTCGT TGCTTCCCTT
CCATTAGATC AATCTGATGA GGGCTCCAGC AGCCAAAAGG AGGAGAGTCC AAGCACCCTA
CAGGTCCTGC CAGACAGTGA GTCTTTACCC AGAAGTGAGA TAGATGAAAA GGTGACTGAT
TTGGTGCAGT TTCTGCTCTT CAAGTATCAA ATGAAGGAGC CGATCACAAA GGCAGAAATA
CTGGAGAGTG TCATAAGAAA TTATGAAGAC CACTTCCCTT TGTTGTTTAG TGAAGCCTCC
GAGTGCATGC TGCTGGTCTT TGGCATTGAT GTAAAGGAAG TGGATCCCAC TGGCCACTCC
TTTGTCCTTG TCACCTCCCT GGGCCTCACC TATGATGGGA TGCTGAGTGA TGTCCAGAGC
ATGCCCAAGA CTGGCATTCT CATACTTATC CTAAGCATAA TCTTCATAGA GGGCTACTGC
ACCCCTGAGG AGGTCATCTG GGAAGCACTG AATATGATGG GGCTGTATGA TGGGATGGAG
CACCTCATTT ATGGGGAGCC CAGGAAGCTG CTCACCCAAG ATTGGGTGCA GGAAAACTAC
CTGGAGTACC GGCAGGTGCC TGGCAGTGAT CCTGCACGGT ATGAGTTTCT GTGGGGTCCA
AGGGCTCATG CTGAAATTAG GAAGATGAGT CTCCTGAAAT TTTTGGCCAA GGTAAATGGG
AGTGATCCAA GATCCTTCCC ACTGTGGTAT GAGGAGGCTT TGAAAGATGA GGAAGAGAGA
GCCCAGGACA GAATTGCCAC CACAGATGAT ACTACTGCCA TGGCCAGTGC AAGTTCTAGC
GCTACAGGTA GCTTCTCCTA CCCTGAATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

High expression of MAGE-A10 cancer-testis antigen in triple-negative breast cancer
Med. Oncol. 29 (3), 1586-1591 (2012)
Badovinac Crnjevic T, Spagnoli G, Juretic A, Jakic-Razumovic J, Podolski P and Saric N.


book

MAGE-A10 is a nuclear protein frequently expressed in high percentages of tumor cells in lung, skin and urothelial malignancies
Int. J. Cancer 129 (5), 1137-1148 (2011)
Schultz-Thater E, Piscuoglio S, Iezzi G, Le Magnen C, Zajac P, Carafa V, Terracciano L, Tornillo L and Spagnoli GC.


book

The use of filamentous bacteriophage fd to deliver MAGE-A10 or MAGE-A3 HLA-A2-restricted peptides and to induce strong antitumor CTL responses
J. Immunol. 180 (6), 3719-3728 (2008)
Sartorius R, Pisu P, D'Apice L, Pizzella L, Romano C, Cortese G, Giorgini A, Santoni A, Velotti F and De Berardinis P.


book

Prognostic impact of cancer/testis antigen expression in advanced stage multiple myeloma patients
Cancer Immun. 8, 2 (2008)
Andrade VC, Vettore AL, Felix RS, Almeida MS, Carvalho F, Oliveira JS, Chauffaille ML, Andriolo A, Caballero OL, Zago MA and Colleoni GW.


book

Breast cancer is a promising target for vaccination using cancer-testis antigens known to elicit immune responses
Breast Cancer Res. 9 (4), R46 (2007)
Taylor M, Bolton LM, Johnson P, Elliott T and Murray N.


book

Identification of intrahepatic cholangiocarcinoma related genes by comparison with normal liver tissues using expressed sequence tags
Biochem. Biophys. Res. Commun. 345 (3), 1022-1032 (2006)
Wang AG, Yoon SY, Oh JH, Jeon YJ, Kim M, Kim JM, Byun SS, Yang JO, Kim JH, Kim DG, Yeom YI, Yoo HS, Kim YS and Kim NS.


book

Melanoma-associated antigens in esophageal adenocarcinoma: identification of novel MAGE-A10 splice variants
Clin. Cancer Res. 10 (17), 5708-5716 (2004)
Lin J, Lin L, Thomas DG, Greenson JK, Giordano TJ, Robinson GS, Barve RA, Weishaar FA, Taylor JM, Orringer MB and Beer DG.


book

cDNA and protein characterization of human MAGE-10
Int. J. Cancer 82 (6), 901-907 (1999)
Rimoldi D, Salvi S, Reed D, Coulie P, Jongeneel VC, De Plaen E, Brasseur F, Rodriguez AM, Boon T and Cerottini JC.


book

The melanoma antigen gene (MAGE) family is clustered in the chromosomal band Xq28
Genomics 29 (3), 725-731 (1995)
Rogner UC, Wilke K, Steck E, Korn B and Poustka A.


book

Structure, chromosomal localization, and expression of 12 genes of the MAGE family
Immunogenetics 40 (5), 360-369 (1994)
De Plaen E, Arden K, Traversari C, Gaforio JJ, Szikora JP, De Smet C, Brasseur F, van der Bruggen P, Lethe B and Lurquin C.


 
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