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MAGEA11 melanoma antigen family A11 [Homo sapiens (human)]

Gene Symbol MAGEA11
Entrez Gene ID 4110
Full Name melanoma antigen family A11
Synonyms CT1.11, MAGE-11, MAGE11, MAGEA-11
General protein information
Preferred Names
melanoma-associated antigen 11
Names
melanoma-associated antigen 11
MAGE-11 antigen
cancer/testis antigen 1.11
cancer/testis antigen family 1, member 11
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

X

Xq28

Summary This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

300344

Disorder Html:





The following MAGEA11 gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MAGEA11 gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu15142 XM_011531163 PREDICTED: Homo sapiens melanoma antigen family A11 (MAGEA11), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $319
OHu58831 XM_011531164 PREDICTED: Homo sapiens melanoma antigen family A11 (MAGEA11), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $319
OHu15142 NM_005366 Homo sapiens melanoma antigen family A11 (MAGEA11), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $379
OHu19105 NM_001011544 Homo sapiens melanoma antigen family A11 (MAGEA11), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $339

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu15142
Accession Version XM_011531163.1
Sequence Information ORF Nucleotide Sequence (Length: 1290bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product melanoma-associated antigen 11 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_011681.17) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGGAGACTC AGTTCCGCAG AGGGGGTCTG GGGTGCAGCC CTGCCAGCAT CAAGAGGAAG 
AAGAAGAGGG AGGACTCAGG AGACTTTGGA CTCCAGGTGA GCACTATGTT CTCAGAGGAC
GACTTCCAGT CAACAGAAAG AGCCCCATAT GGTCCACAAC TACAGTGGTC CCAGGATCTG
CCAAGAGTCC AGGTTTTTAG AGAACAGGCC AACCTGGAGG ACAGGAGTCC CAGGAGAACC
CAGAGGATCA CTGGAGGAGA ACAAGTGCTG TGGGGCCCCA TCACCCAGAT ATTTCCCACA
GTTCGGCCTG CTGACCTAAC CAGAGTCATC ATGCCTCTTG AGCAAAGAAG TCAGCACTGC
AAGCCTGAGG AAGGCCTTCA GGCCCAAGAA GAAGACCTGG GCCTGGTGGG TGCACAGGCT
CTCCAAGCTG AGGAGCAGGA GGCTGCCTTC TTCTCCTCTA CTCTGAATGT GGGCACTCTA
GAGGAGTTGC CTGCTGCTGA GTCACCAAGT CCTCCCCAGA GTCCTCAGGA AGAGTCCTTC
TCTCCCACTG CCATGGATGC CATCTTTGGG AGCCTATCTG ATGAGGGCTC TGGCAGCCAA
GAAAAGGAGG GGCCAAGTAC CTCGCCTGAC CTGATAGACC CTGAGTCCTT TTCCCAAGAT
ATACTACATG ACAAGATAAT TGATTTGGTT CATTTATTGC TCCGCAAGTA TCGAGTCAAG
GGGCTGATCA CAAAGGCAGA AATGCTGGGG AGTGTCATCA AAAATTATGA GGACTACTTT
CCTGAGATAT TTAGGGAAGC CTCTGTATGC ATGCAACTGC TCTTTGGCAT TGATGTGAAG
GAAGTGGACC CCACTAGCCA CTCCTATGTC CTTGTCACCT CCCTCAACCT CTCTTATGAT
GGCATACAGT GTAATGAGCA GAGCATGCCC AAGTCTGGCC TCCTGATAAT AGTCCTGGGT
GTAATCTTCA TGGAGGGGAA CTGCATCCCT GAAGAGGTTA TGTGGGAAGT CCTGAGCATT
ATGGGGGTGT ATGCTGGAAG GGAGCACTTC CTCTTTGGGG AGCCCAAGAG GCTCCTTACC
CAAAATTGGG TGCAGGAAAA GTACCTGGTG TACCGGCAGG TGCCCGGCAC TGATCCTGCA
TGCTATGAGT TCCTGTGGGG TCCAAGGGCC CACGCTGAGA CCAGCAAGAT GAAAGTTCTT
GAGTACATAG CCAATGCCAA TGGGAGGGAT CCCACTTCTT ACCCATCCCT GTATGAAGAT
GCTTTGAGAG AGGAGGGAGA GGGAGTCTGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqXP_011529465.1
CDS594..1883
Misc Feature(1)930..1217(+)
Misc Feature(2)1278..1790(+)
Translation
Position Chain Variation Link
77 77 c, g dbSNP:191650275
643 643 c, t dbSNP:376083752
711 711 g, t dbSNP:73640692
713 713 c, t dbSNP:73640691
875 875 c, t dbSNP:267606378
1306 1306 a, c, g dbSNP:6641350
1346 1346 a, t dbSNP:41312624
1670 1670 c, t dbSNP:2233050
1939 1939 a, g dbSNP:73606281
2117 2117 c, t dbSNP:10126316

Target ORF information:

RefSeq Version XM_011531163
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens melanoma antigen family A11 (MAGEA11), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011531163

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGGAGACTC AGTTCCGCAG AGGGGGTCTG GGGTGCAGCC CTGCCAGCAT CAAGAGGAAG 
AAGAAGAGGG AGGACTCAGG AGACTTTGGA CTCCAGGTGA GCACTATGTT CTCAGAGGAC
GACTTCCAGT CAACAGAAAG AGCCCCATAT GGTCCACAAC TACAGTGGTC CCAGGATCTG
CCAAGAGTCC AGGTTTTTAG AGAACAGGCC AACCTGGAGG ACAGGAGTCC CAGGAGAACC
CAGAGGATCA CTGGAGGAGA ACAAGTGCTG TGGGGCCCCA TCACCCAGAT ATTTCCCACA
GTTCGGCCTG CTGACCTAAC CAGAGTCATC ATGCCTCTTG AGCAAAGAAG TCAGCACTGC
AAGCCTGAGG AAGGCCTTCA GGCCCAAGAA GAAGACCTGG GCCTGGTGGG TGCACAGGCT
CTCCAAGCTG AGGAGCAGGA GGCTGCCTTC TTCTCCTCTA CTCTGAATGT GGGCACTCTA
GAGGAGTTGC CTGCTGCTGA GTCACCAAGT CCTCCCCAGA GTCCTCAGGA AGAGTCCTTC
TCTCCCACTG CCATGGATGC CATCTTTGGG AGCCTATCTG ATGAGGGCTC TGGCAGCCAA
GAAAAGGAGG GGCCAAGTAC CTCGCCTGAC CTGATAGACC CTGAGTCCTT TTCCCAAGAT
ATACTACATG ACAAGATAAT TGATTTGGTT CATTTATTGC TCCGCAAGTA TCGAGTCAAG
GGGCTGATCA CAAAGGCAGA AATGCTGGGG AGTGTCATCA AAAATTATGA GGACTACTTT
CCTGAGATAT TTAGGGAAGC CTCTGTATGC ATGCAACTGC TCTTTGGCAT TGATGTGAAG
GAAGTGGACC CCACTAGCCA CTCCTATGTC CTTGTCACCT CCCTCAACCT CTCTTATGAT
GGCATACAGT GTAATGAGCA GAGCATGCCC AAGTCTGGCC TCCTGATAAT AGTCCTGGGT
GTAATCTTCA TGGAGGGGAA CTGCATCCCT GAAGAGGTTA TGTGGGAAGT CCTGAGCATT
ATGGGGGTGT ATGCTGGAAG GGAGCACTTC CTCTTTGGGG AGCCCAAGAG GCTCCTTACC
CAAAATTGGG TGCAGGAAAA GTACCTGGTG TACCGGCAGG TGCCCGGCAC TGATCCTGCA
TGCTATGAGT TCCTGTGGGG TCCAAGGGCC CACGCTGAGA CCAGCAAGAT GAAAGTTCTT
GAGTACATAG CCAATGCCAA TGGGAGGGAT CCCACTTCTT ACCCATCCCT GTATGAAGAT
GCTTTGAGAG AGGAGGGAGA GGGAGTCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu58831
Accession Version XM_011531164.1
Sequence Information ORF Nucleotide Sequence (Length: 1266bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product melanoma-associated antigen 11 isoform X2
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_011681.17) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGACAGGTC AGCAGGTGGA GCCACACCTG ATCAGCAGAG GGAGGAGTCC CAGGATCTTT 
AGGACTCAAG GTGTGAGCAC TATGTTCTCA GAGGACGACT TCCAGTCAAC AGAAAGAGCC
CCATATGGTC CACAACTACA GTGGTCCCAG GATCTGCCAA GAGTCCAGGT TTTTAGAGAA
CAGGCCAACC TGGAGGACAG GAGTCCCAGG AGAACCCAGA GGATCACTGG AGGAGAACAA
GTGCTGTGGG GCCCCATCAC CCAGATATTT CCCACAGTTC GGCCTGCTGA CCTAACCAGA
GTCATCATGC CTCTTGAGCA AAGAAGTCAG CACTGCAAGC CTGAGGAAGG CCTTCAGGCC
CAAGAAGAAG ACCTGGGCCT GGTGGGTGCA CAGGCTCTCC AAGCTGAGGA GCAGGAGGCT
GCCTTCTTCT CCTCTACTCT GAATGTGGGC ACTCTAGAGG AGTTGCCTGC TGCTGAGTCA
CCAAGTCCTC CCCAGAGTCC TCAGGAAGAG TCCTTCTCTC CCACTGCCAT GGATGCCATC
TTTGGGAGCC TATCTGATGA GGGCTCTGGC AGCCAAGAAA AGGAGGGGCC AAGTACCTCG
CCTGACCTGA TAGACCCTGA GTCCTTTTCC CAAGATATAC TACATGACAA GATAATTGAT
TTGGTTCATT TATTGCTCCG CAAGTATCGA GTCAAGGGGC TGATCACAAA GGCAGAAATG
CTGGGGAGTG TCATCAAAAA TTATGAGGAC TACTTTCCTG AGATATTTAG GGAAGCCTCT
GTATGCATGC AACTGCTCTT TGGCATTGAT GTGAAGGAAG TGGACCCCAC TAGCCACTCC
TATGTCCTTG TCACCTCCCT CAACCTCTCT TATGATGGCA TACAGTGTAA TGAGCAGAGC
ATGCCCAAGT CTGGCCTCCT GATAATAGTC CTGGGTGTAA TCTTCATGGA GGGGAACTGC
ATCCCTGAAG AGGTTATGTG GGAAGTCCTG AGCATTATGG GGGTGTATGC TGGAAGGGAG
CACTTCCTCT TTGGGGAGCC CAAGAGGCTC CTTACCCAAA ATTGGGTGCA GGAAAAGTAC
CTGGTGTACC GGCAGGTGCC CGGCACTGAT CCTGCATGCT ATGAGTTCCT GTGGGGTCCA
AGGGCCCACG CTGAGACCAG CAAGATGAAA GTTCTTGAGT ACATAGCCAA TGCCAATGGG
AGGGATCCCA CTTCTTACCC ATCCCTGTAT GAAGATGCTT TGAGAGAGGA GGGAGAGGGA
GTCTGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqXP_011529466.1
CDS757..2022
Misc Feature(1)1069..1356(+)
Misc Feature(2)1417..1929(+)
Translation
Position Chain Variation Link
850 850 g, t dbSNP:73640692
852 852 c, t dbSNP:73640691
1014 1014 c, t dbSNP:267606378
1445 1445 a, c, g dbSNP:6641350
1485 1485 a, t dbSNP:41312624
1809 1809 c, t dbSNP:2233050
2078 2078 a, g dbSNP:73606281
2256 2256 c, t dbSNP:10126316

Target ORF information:

RefSeq Version XM_011531164
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens melanoma antigen family A11 (MAGEA11), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011531164

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGACAGGTC AGCAGGTGGA GCCACACCTG ATCAGCAGAG GGAGGAGTCC CAGGATCTTT 
AGGACTCAAG GTGTGAGCAC TATGTTCTCA GAGGACGACT TCCAGTCAAC AGAAAGAGCC
CCATATGGTC CACAACTACA GTGGTCCCAG GATCTGCCAA GAGTCCAGGT TTTTAGAGAA
CAGGCCAACC TGGAGGACAG GAGTCCCAGG AGAACCCAGA GGATCACTGG AGGAGAACAA
GTGCTGTGGG GCCCCATCAC CCAGATATTT CCCACAGTTC GGCCTGCTGA CCTAACCAGA
GTCATCATGC CTCTTGAGCA AAGAAGTCAG CACTGCAAGC CTGAGGAAGG CCTTCAGGCC
CAAGAAGAAG ACCTGGGCCT GGTGGGTGCA CAGGCTCTCC AAGCTGAGGA GCAGGAGGCT
GCCTTCTTCT CCTCTACTCT GAATGTGGGC ACTCTAGAGG AGTTGCCTGC TGCTGAGTCA
CCAAGTCCTC CCCAGAGTCC TCAGGAAGAG TCCTTCTCTC CCACTGCCAT GGATGCCATC
TTTGGGAGCC TATCTGATGA GGGCTCTGGC AGCCAAGAAA AGGAGGGGCC AAGTACCTCG
CCTGACCTGA TAGACCCTGA GTCCTTTTCC CAAGATATAC TACATGACAA GATAATTGAT
TTGGTTCATT TATTGCTCCG CAAGTATCGA GTCAAGGGGC TGATCACAAA GGCAGAAATG
CTGGGGAGTG TCATCAAAAA TTATGAGGAC TACTTTCCTG AGATATTTAG GGAAGCCTCT
GTATGCATGC AACTGCTCTT TGGCATTGAT GTGAAGGAAG TGGACCCCAC TAGCCACTCC
TATGTCCTTG TCACCTCCCT CAACCTCTCT TATGATGGCA TACAGTGTAA TGAGCAGAGC
ATGCCCAAGT CTGGCCTCCT GATAATAGTC CTGGGTGTAA TCTTCATGGA GGGGAACTGC
ATCCCTGAAG AGGTTATGTG GGAAGTCCTG AGCATTATGG GGGTGTATGC TGGAAGGGAG
CACTTCCTCT TTGGGGAGCC CAAGAGGCTC CTTACCCAAA ATTGGGTGCA GGAAAAGTAC
CTGGTGTACC GGCAGGTGCC CGGCACTGAT CCTGCATGCT ATGAGTTCCT GTGGGGTCCA
AGGGCCCACG CTGAGACCAG CAAGATGAAA GTTCTTGAGT ACATAGCCAA TGCCAATGGG
AGGGATCCCA CTTCTTACCC ATCCCTGTAT GAAGATGCTT TGAGAGAGGA GGGAGAGGGA
GTCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu15142
Accession Version NM_005366.4
Sequence Information ORF Nucleotide Sequence (Length: 1290bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product melanoma-associated antigen 11 isoform a
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BQ212898.1, BC004479.2 and AI691089.1. On May 16, 2005 this sequence version replaced gi:29029614. Summary: This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]. Transcript Variant: This variant (1) encodes the longer isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BQ224197.1, AY747607.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2148093 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGGAGACTC AGTTCCGCAG AGGGGGTCTG GGGTGCAGCC CTGCCAGCAT CAAGAGGAAG 
AAGAAGAGGG AGGACTCAGG AGACTTTGGA CTCCAGGTGA GCACTATGTT CTCAGAGGAC
GACTTCCAGT CAACAGAAAG AGCCCCATAT GGTCCACAAC TACAGTGGTC CCAGGATCTG
CCAAGAGTCC AGGTTTTTAG AGAACAGGCC AACCTGGAGG ACAGGAGTCC CAGGAGAACC
CAGAGGATCA CTGGAGGAGA ACAAGTGCTG TGGGGCCCCA TCACCCAGAT ATTTCCCACA
GTTCGGCCTG CTGACCTAAC CAGAGTCATC ATGCCTCTTG AGCAAAGAAG TCAGCACTGC
AAGCCTGAGG AAGGCCTTCA GGCCCAAGAA GAAGACCTGG GCCTGGTGGG TGCACAGGCT
CTCCAAGCTG AGGAGCAGGA GGCTGCCTTC TTCTCCTCTA CTCTGAATGT GGGCACTCTA
GAGGAGTTGC CTGCTGCTGA GTCACCAAGT CCTCCCCAGA GTCCTCAGGA AGAGTCCTTC
TCTCCCACTG CCATGGATGC CATCTTTGGG AGCCTATCTG ATGAGGGCTC TGGCAGCCAA
GAAAAGGAGG GGCCAAGTAC CTCGCCTGAC CTGATAGACC CTGAGTCCTT TTCCCAAGAT
ATACTACATG ACAAGATAAT TGATTTGGTT CATTTATTGC TCCGCAAGTA TCGAGTCAAG
GGGCTGATCA CAAAGGCAGA AATGCTGGGG AGTGTCATCA AAAATTATGA GGACTACTTT
CCTGAGATAT TTAGGGAAGC CTCTGTATGC ATGCAACTGC TCTTTGGCAT TGATGTGAAG
GAAGTGGACC CCACTAGCCA CTCCTATGTC CTTGTCACCT CCCTCAACCT CTCTTATGAT
GGCATACAGT GTAATGAGCA GAGCATGCCC AAGTCTGGCC TCCTGATAAT AGTCCTGGGT
GTAATCTTCA TGGAGGGGAA CTGCATCCCT GAAGAGGTTA TGTGGGAAGT CCTGAGCATT
ATGGGGGTGT ATGCTGGAAG GGAGCACTTC CTCTTTGGGG AGCCCAAGAG GCTCCTTACC
CAAAATTGGG TGCAGGAAAA GTACCTGGTG TACCGGCAGG TGCCCGGCAC TGATCCTGCA
TGCTATGAGT TCCTGTGGGG TCCAAGGGCC CACGCTGAGA CCAGCAAGAT GAAAGTTCTT
GAGTACATAG CCAATGCCAA TGGGAGGGAT CCCACTTCTT ACCCATCCCT GTATGAAGAT
GCTTTGAGAG AGGAGGGAGA GGGAGTCTGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_005357.2
CDS103..1392
Misc Feature(1)97..99(+)
Misc Feature(2)439..726(+)
Misc Feature(3)787..1299(+)
Exon (1)1..85
Gene:MAGEA11
Gene Synonym:
Exon (2)86..198
Gene:MAGEA11
Gene Synonym:
Exon (3)199..294
Gene:MAGEA11
Gene Synonym:
Exon (4)295..368
Gene:MAGEA11
Gene Synonym:
Exon (5)369..1884
Gene:MAGEA11
Gene Synonym:
Translation
Position Chain Variation Link
152 152 c, t dbSNP:376083752
220 220 g, t dbSNP:73640692
222 222 c, t dbSNP:73640691
384 384 c, t dbSNP:267606378
815 815 a, c, g dbSNP:6641350
855 855 a, t dbSNP:41312624
1179 1179 c, t dbSNP:2233050
1448 1448 a, g dbSNP:73606281
1626 1626 c, t dbSNP:10126316

Target ORF information:

RefSeq Version NM_005366
Organism Homo sapiens (human)
Definition Homo sapiens melanoma antigen family A11 (MAGEA11), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_005366

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGGAGACTC AGTTCCGCAG AGGGGGTCTG GGGTGCAGCC CTGCCAGCAT CAAGAGGAAG 
AAGAAGAGGG AGGACTCAGG AGACTTTGGA CTCCAGGTGA GCACTATGTT CTCAGAGGAC
GACTTCCAGT CAACAGAAAG AGCCCCATAT GGTCCACAAC TACAGTGGTC CCAGGATCTG
CCAAGAGTCC AGGTTTTTAG AGAACAGGCC AACCTGGAGG ACAGGAGTCC CAGGAGAACC
CAGAGGATCA CTGGAGGAGA ACAAGTGCTG TGGGGCCCCA TCACCCAGAT ATTTCCCACA
GTTCGGCCTG CTGACCTAAC CAGAGTCATC ATGCCTCTTG AGCAAAGAAG TCAGCACTGC
AAGCCTGAGG AAGGCCTTCA GGCCCAAGAA GAAGACCTGG GCCTGGTGGG TGCACAGGCT
CTCCAAGCTG AGGAGCAGGA GGCTGCCTTC TTCTCCTCTA CTCTGAATGT GGGCACTCTA
GAGGAGTTGC CTGCTGCTGA GTCACCAAGT CCTCCCCAGA GTCCTCAGGA AGAGTCCTTC
TCTCCCACTG CCATGGATGC CATCTTTGGG AGCCTATCTG ATGAGGGCTC TGGCAGCCAA
GAAAAGGAGG GGCCAAGTAC CTCGCCTGAC CTGATAGACC CTGAGTCCTT TTCCCAAGAT
ATACTACATG ACAAGATAAT TGATTTGGTT CATTTATTGC TCCGCAAGTA TCGAGTCAAG
GGGCTGATCA CAAAGGCAGA AATGCTGGGG AGTGTCATCA AAAATTATGA GGACTACTTT
CCTGAGATAT TTAGGGAAGC CTCTGTATGC ATGCAACTGC TCTTTGGCAT TGATGTGAAG
GAAGTGGACC CCACTAGCCA CTCCTATGTC CTTGTCACCT CCCTCAACCT CTCTTATGAT
GGCATACAGT GTAATGAGCA GAGCATGCCC AAGTCTGGCC TCCTGATAAT AGTCCTGGGT
GTAATCTTCA TGGAGGGGAA CTGCATCCCT GAAGAGGTTA TGTGGGAAGT CCTGAGCATT
ATGGGGGTGT ATGCTGGAAG GGAGCACTTC CTCTTTGGGG AGCCCAAGAG GCTCCTTACC
CAAAATTGGG TGCAGGAAAA GTACCTGGTG TACCGGCAGG TGCCCGGCAC TGATCCTGCA
TGCTATGAGT TCCTGTGGGG TCCAAGGGCC CACGCTGAGA CCAGCAAGAT GAAAGTTCTT
GAGTACATAG CCAATGCCAA TGGGAGGGAT CCCACTTCTT ACCCATCCCT GTATGAAGAT
GCTTTGAGAG AGGAGGGAGA GGGAGTCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu19105
Accession Version NM_001011544.1
Sequence Information ORF Nucleotide Sequence (Length: 1203bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product melanoma-associated antigen 11 isoform b
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BX337921.2, BC004479.2 and AI691089.1. This sequence is a reference standard in the RefSeqGene project. Summary: This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]. Transcript Variant: This variant (2) differs in the 5' UTR and CDS compared to variant 1. The resulting isoform (b) is shorter and has a distinct N-terminus compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BX337921.2, BI092645.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1968968, SAMEA2142853 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGAGCAAGG TGAGCACTAT GTTCTCAGAG GACGACTTCC AGTCAACAGA AAGAGCCCCA 
TATGGTCCAC AACTACAGTG GTCCCAGGAT CTGCCAAGAG TCCAGGTTTT TAGAGAACAG
GCCAACCTGG AGGACAGGAG TCCCAGGAGA ACCCAGAGGA TCACTGGAGG AGAACAAGTG
CTGTGGGGCC CCATCACCCA GATATTTCCC ACAGTTCGGC CTGCTGACCT AACCAGAGTC
ATCATGCCTC TTGAGCAAAG AAGTCAGCAC TGCAAGCCTG AGGAAGGCCT TCAGGCCCAA
GAAGAAGACC TGGGCCTGGT GGGTGCACAG GCTCTCCAAG CTGAGGAGCA GGAGGCTGCC
TTCTTCTCCT CTACTCTGAA TGTGGGCACT CTAGAGGAGT TGCCTGCTGC TGAGTCACCA
AGTCCTCCCC AGAGTCCTCA GGAAGAGTCC TTCTCTCCCA CTGCCATGGA TGCCATCTTT
GGGAGCCTAT CTGATGAGGG CTCTGGCAGC CAAGAAAAGG AGGGGCCAAG TACCTCGCCT
GACCTGATAG ACCCTGAGTC CTTTTCCCAA GATATACTAC ATGACAAGAT AATTGATTTG
GTTCATTTAT TGCTCCGCAA GTATCGAGTC AAGGGGCTGA TCACAAAGGC AGAAATGCTG
GGGAGTGTCA TCAAAAATTA TGAGGACTAC TTTCCTGAGA TATTTAGGGA AGCCTCTGTA
TGCATGCAAC TGCTCTTTGG CATTGATGTG AAGGAAGTGG ACCCCACTAG CCACTCCTAT
GTCCTTGTCA CCTCCCTCAA CCTCTCTTAT GATGGCATAC AGTGTAATGA GCAGAGCATG
CCCAAGTCTG GCCTCCTGAT AATAGTCCTG GGTGTAATCT TCATGGAGGG GAACTGCATC
CCTGAAGAGG TTATGTGGGA AGTCCTGAGC ATTATGGGGG TGTATGCTGG AAGGGAGCAC
TTCCTCTTTG GGGAGCCCAA GAGGCTCCTT ACCCAAAATT GGGTGCAGGA AAAGTACCTG
GTGTACCGGC AGGTGCCCGG CACTGATCCT GCATGCTATG AGTTCCTGTG GGGTCCAAGG
GCCCACGCTG AGACCAGCAA GATGAAAGTT CTTGAGTACA TAGCCAATGC CAATGGGAGG
GATCCCACTT CTTACCCATC CCTGTATGAA GATGCTTTGA GAGAGGAGGG AGAGGGAGTC
TGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_001011544.1
CDS191..1393
Misc Feature(1)170..172(+)
Misc Feature(2)440..727(+)
Misc Feature(3)788..1300(+)
Exon (1)1..52
Gene:MAGEA11
Gene Synonym:
Exon (2)53..199
Gene:MAGEA11
Gene Synonym:
Exon (3)200..295
Gene:MAGEA11
Gene Synonym:
Exon (4)296..369
Gene:MAGEA11
Gene Synonym:
Exon (5)370..1885
Gene:MAGEA11
Gene Synonym:
Translation
Position Chain Variation Link
38 38 c, g dbSNP:191650275
221 221 g, t dbSNP:73640692
223 223 c, t dbSNP:73640691
385 385 c, t dbSNP:267606378
816 816 a, c, g dbSNP:6641350
856 856 a, t dbSNP:41312624
1180 1180 c, t dbSNP:2233050
1449 1449 a, g dbSNP:73606281
1627 1627 c, t dbSNP:10126316

Target ORF information:

RefSeq Version NM_001011544
Organism Homo sapiens (human)
Definition Homo sapiens melanoma antigen family A11 (MAGEA11), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001011544

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGAGCAAGG TGAGCACTAT GTTCTCAGAG GACGACTTCC AGTCAACAGA AAGAGCCCCA 
TATGGTCCAC AACTACAGTG GTCCCAGGAT CTGCCAAGAG TCCAGGTTTT TAGAGAACAG
GCCAACCTGG AGGACAGGAG TCCCAGGAGA ACCCAGAGGA TCACTGGAGG AGAACAAGTG
CTGTGGGGCC CCATCACCCA GATATTTCCC ACAGTTCGGC CTGCTGACCT AACCAGAGTC
ATCATGCCTC TTGAGCAAAG AAGTCAGCAC TGCAAGCCTG AGGAAGGCCT TCAGGCCCAA
GAAGAAGACC TGGGCCTGGT GGGTGCACAG GCTCTCCAAG CTGAGGAGCA GGAGGCTGCC
TTCTTCTCCT CTACTCTGAA TGTGGGCACT CTAGAGGAGT TGCCTGCTGC TGAGTCACCA
AGTCCTCCCC AGAGTCCTCA GGAAGAGTCC TTCTCTCCCA CTGCCATGGA TGCCATCTTT
GGGAGCCTAT CTGATGAGGG CTCTGGCAGC CAAGAAAAGG AGGGGCCAAG TACCTCGCCT
GACCTGATAG ACCCTGAGTC CTTTTCCCAA GATATACTAC ATGACAAGAT AATTGATTTG
GTTCATTTAT TGCTCCGCAA GTATCGAGTC AAGGGGCTGA TCACAAAGGC AGAAATGCTG
GGGAGTGTCA TCAAAAATTA TGAGGACTAC TTTCCTGAGA TATTTAGGGA AGCCTCTGTA
TGCATGCAAC TGCTCTTTGG CATTGATGTG AAGGAAGTGG ACCCCACTAG CCACTCCTAT
GTCCTTGTCA CCTCCCTCAA CCTCTCTTAT GATGGCATAC AGTGTAATGA GCAGAGCATG
CCCAAGTCTG GCCTCCTGAT AATAGTCCTG GGTGTAATCT TCATGGAGGG GAACTGCATC
CCTGAAGAGG TTATGTGGGA AGTCCTGAGC ATTATGGGGG TGTATGCTGG AAGGGAGCAC
TTCCTCTTTG GGGAGCCCAA GAGGCTCCTT ACCCAAAATT GGGTGCAGGA AAAGTACCTG
GTGTACCGGC AGGTGCCCGG CACTGATCCT GCATGCTATG AGTTCCTGTG GGGTCCAAGG
GCCCACGCTG AGACCAGCAA GATGAAAGTT CTTGAGTACA TAGCCAATGC CAATGGGAGG
GATCCCACTT CTTACCCATC CCTGTATGAA GATGCTTTGA GAGAGGAGGG AGAGGGAGTC
TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.