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MAGEB2 cDNA ORF clone, Homo sapiens (human)

Gene Symbol MAGEB2
Entrez Gene ID 4113
Full Name melanoma antigen family B2
Synonyms CT3.2, DAM6, MAGE-XP-2
General protein information
Preferred Names
melanoma-associated antigen B2
Names
melanoma-associated antigen B2
MAGE-B2 antigen
MAGE XP-2 antigen
cancer/testis antigen 3.2
cancer/testis antigen family 3, member 2
DSS-AHC critical interval MAGE superfamily 6
DSS/AHC critical interval MAGE superfamily 6
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

X

Xp21.3

Summary This gene is a member of the MAGEB gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 68% sequence identity to each other. The promoters and first exons of the MAGEB genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. This gene is localized in the DSS (dosage-sensitive sex reversal) critical region. It is expressed in testis and placenta, and in a significant fraction of tumors of various histological types. The MAGEB genes are clustered on chromosome Xp22-p21. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

300098


mRNA and Protein(s)

mRNA Protein Name
XM_011545512 XP_011543814 melanoma-associated antigen B2 isoform X1
NM_002364 NP_002355 melanoma-associated antigen B2


Homo sapiens (human) MAGEB2 NP_002355.2
Pan troglodytes (chimpanzee) MAGEB2 XP_520990.4
Macaca mulatta (Rhesus monkey) MAGEB2 XP_001094313.1
Canis lupus familiaris (dog) MAGEB1 XP_005641278.1
Canis lupus familiaris (dog) MAGEB4 XP_005641277.1
Bos taurus (cattle) LOC781486 XP_002700309.1
Bos taurus (cattle) LOC786836 NP_001193704.1
Bos taurus (cattle) LOC788399 XP_002700297.1
Bos taurus (cattle) LOC101905249 XP_005228381.1
Mus musculus (house mouse) Mageb4 NP_001028664.2
Rattus norvegicus (Norway rat) Mageb2 XP_006257052.1


GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following MAGEB2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MAGEB2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu22525 XM_011545512 PREDICTED: Homo sapiens melanoma antigen family B2 (MAGEB2), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $139.30
$199.00
OHu22525 NM_002364 Homo sapiens melanoma antigen family B2 (MAGEB2), mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $139.30
$199.00
Next-day Shipping ORF Clones ( in default vector with tag)
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu22525
Clone ID Related Accession (Same CDS sequence) NM_002364 , XM_011545512
Accession Version XM_011545512.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 960bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product melanoma-associated antigen B2 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_167197.2) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
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841
901
ATGCCTCGTG GTCAGAAGAG TAAGCTCCGT GCCCGTGAGA AACGCCGCAA GGCCCGAGAT 
GAGACCCGGG GTCTCAATGT TCCTCAGGTC ACTGAAGCAG AGGAAGAAGA GGCCCCCTGC
TGTTCCTCTT CTGTTTCTGG GGGTGCTGCT TCAAGCTCTC CTGCTGCTGG CATTCCCCAG
GAGCCTCAGA GAGCCCCAAC CACTGCCGCT GCTGCGGCTG CGGGTGTTTC ATCCACAAAA
TCTAAAAAAG GTGCCAAGAG CCACCAAGGT GAGAAAAATG CAAGTTCCTC CCAGGCCTCA
ACATCCACTA AGAGCCCAAG CGAAGATCCT CTAACCAGGA AGTCAGGGTC GTTGGTGCAG
TTCCTGTTGT ACAAGTATAA AATAAAAAAG TCCGTTACAA AGGGAGAAAT GCTGAAAATT
GTTGGCAAAA GGTTCAGGGA GCACTTCCCT GAGATCCTCA AGAAAGCCTC TGAGGGCCTC
AGTGTTGTCT TTGGCCTTGA GCTGAATAAA GTCAACCCCA ACGGCCACAC TTACACCTTC
ATCGACAAGG TAGACCTCAC TGATGAGGAA TCCCTGCTCA GTTCCTGGGA CTTTCCCAGG
AGAAAGCTTC TGATGCCTCT CCTGGGTGTG ATCTTCTTAA ATGGCAACTC AGCTACTGAG
GAAGAGATCT GGGAATTCCT GAATATGTTG GGAGTCTATG ATGGAGAGGA GCACTCAGTC
TTTGGGGAAC CCTGGAAGCT CATCACCAAA GATCTGGTGC AGGAAAAATA TCTGGAGTAC
AAGCAGGTGC CCAGCAGTGA TCCCCCACGC TTTCAATTCC TGTGGGGTCC GAGAGCCTAT
GCTGAAACCA GCAAGATGAA AGTCCTGGAG TTTTTGGCCA AGGTAAATGG TACCACCCCC
TGTGCCTTCC CAACCCATTA CGAAGAAGCT TTGAAAGATG AAGAGAAAGC CGGAGTCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011543814.1
CDS144..1103
Misc Feature(1)150..419(+)
Misc Feature(2)495..1007(+)
Translation

Target ORF information:

RefSeq Version XM_011545512
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens melanoma antigen family B2 (MAGEB2), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011545512

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGCCTCGTG GTCAGAAGAG TAAGCTCCGT GCCCGTGAGA AACGCCGCAA GGCCCGAGAT 
GAGACCCGGG GTCTCAATGT TCCTCAGGTC ACTGAAGCAG AGGAAGAAGA GGCCCCCTGC
TGTTCCTCTT CTGTTTCTGG GGGTGCTGCT TCAAGCTCTC CTGCTGCTGG CATTCCCCAG
GAGCCTCAGA GAGCCCCAAC CACTGCCGCT GCTGCGGCTG CGGGTGTTTC ATCCACAAAA
TCTAAAAAAG GTGCCAAGAG CCACCAAGGT GAGAAAAATG CAAGTTCCTC CCAGGCCTCA
ACATCCACTA AGAGCCCAAG CGAAGATCCT CTAACCAGGA AGTCAGGGTC GTTGGTGCAG
TTCCTGTTGT ACAAGTATAA AATAAAAAAG TCCGTTACAA AGGGAGAAAT GCTGAAAATT
GTTGGCAAAA GGTTCAGGGA GCACTTCCCT GAGATCCTCA AGAAAGCCTC TGAGGGCCTC
AGTGTTGTCT TTGGCCTTGA GCTGAATAAA GTCAACCCCA ACGGCCACAC TTACACCTTC
ATCGACAAGG TAGACCTCAC TGATGAGGAA TCCCTGCTCA GTTCCTGGGA CTTTCCCAGG
AGAAAGCTTC TGATGCCTCT CCTGGGTGTG ATCTTCTTAA ATGGCAACTC AGCTACTGAG
GAAGAGATCT GGGAATTCCT GAATATGTTG GGAGTCTATG ATGGAGAGGA GCACTCAGTC
TTTGGGGAAC CCTGGAAGCT CATCACCAAA GATCTGGTGC AGGAAAAATA TCTGGAGTAC
AAGCAGGTGC CCAGCAGTGA TCCCCCACGC TTTCAATTCC TGTGGGGTCC GAGAGCCTAT
GCTGAAACCA GCAAGATGAA AGTCCTGGAG TTTTTGGCCA AGGTAAATGG TACCACCCCC
TGTGCCTTCC CAACCCATTA CGAAGAAGCT TTGAAAGATG AAGAGAAAGC CGGAGTCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu22525
Clone ID Related Accession (Same CDS sequence) NM_002364 , XM_011545512
Accession Version NM_002364.4 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 960bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product melanoma-associated antigen B2
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC005185.1 and AK223081.1. This sequence is a reference standard in the RefSeqGene project. On or before Jul 8, 2009 this sequence version replaced gi:239757771, gi:34335239. ##Evidence-Data-START## Transcript exon combination :: BC026071.2, AF015766.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2145122 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGCCTCGTG GTCAGAAGAG TAAGCTCCGT GCCCGTGAGA AACGCCGCAA GGCCCGAGAT 
GAGACCCGGG GTCTCAATGT TCCTCAGGTC ACTGAAGCAG AGGAAGAAGA GGCCCCCTGC
TGTTCCTCTT CTGTTTCTGG GGGTGCTGCT TCAAGCTCTC CTGCTGCTGG CATTCCCCAG
GAGCCTCAGA GAGCCCCAAC CACTGCCGCT GCTGCGGCTG CGGGTGTTTC ATCCACAAAA
TCTAAAAAAG GTGCCAAGAG CCACCAAGGT GAGAAAAATG CAAGTTCCTC CCAGGCCTCA
ACATCCACTA AGAGCCCAAG CGAAGATCCT CTAACCAGGA AGTCAGGGTC GTTGGTGCAG
TTCCTGTTGT ACAAGTATAA AATAAAAAAG TCCGTTACAA AGGGAGAAAT GCTGAAAATT
GTTGGCAAAA GGTTCAGGGA GCACTTCCCT GAGATCCTCA AGAAAGCCTC TGAGGGCCTC
AGTGTTGTCT TTGGCCTTGA GCTGAATAAA GTCAACCCCA ACGGCCACAC TTACACCTTC
ATCGACAAGG TAGACCTCAC TGATGAGGAA TCCCTGCTCA GTTCCTGGGA CTTTCCCAGG
AGAAAGCTTC TGATGCCTCT CCTGGGTGTG ATCTTCTTAA ATGGCAACTC AGCTACTGAG
GAAGAGATCT GGGAATTCCT GAATATGTTG GGAGTCTATG ATGGAGAGGA GCACTCAGTC
TTTGGGGAAC CCTGGAAGCT CATCACCAAA GATCTGGTGC AGGAAAAATA TCTGGAGTAC
AAGCAGGTGC CCAGCAGTGA TCCCCCACGC TTTCAATTCC TGTGGGGTCC GAGAGCCTAT
GCTGAAACCA GCAAGATGAA AGTCCTGGAG TTTTTGGCCA AGGTAAATGG TACCACCCCC
TGTGCCTTCC CAACCCATTA CGAAGAAGCT TTGAAAGATG AAGAGAAAGC CGGAGTCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_002355.2
CDS104..1063
Misc Feature(1)110..379(+)
Misc Feature(2)332..334(+)
Misc Feature(3)416..418(+)
Misc Feature(4)455..967(+)
Exon (1)1..98
Gene:MAGEB2
Gene Synonym:
Exon (2)99..1612
Gene:MAGEB2
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_002364
Organism Homo sapiens (human)
Definition Homo sapiens melanoma antigen family B2 (MAGEB2), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_002364

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGCCTCGTG GTCAGAAGAG TAAGCTCCGT GCCCGTGAGA AACGCCGCAA GGCCCGAGAT 
GAGACCCGGG GTCTCAATGT TCCTCAGGTC ACTGAAGCAG AGGAAGAAGA GGCCCCCTGC
TGTTCCTCTT CTGTTTCTGG GGGTGCTGCT TCAAGCTCTC CTGCTGCTGG CATTCCCCAG
GAGCCTCAGA GAGCCCCAAC CACTGCCGCT GCTGCGGCTG CGGGTGTTTC ATCCACAAAA
TCTAAAAAAG GTGCCAAGAG CCACCAAGGT GAGAAAAATG CAAGTTCCTC CCAGGCCTCA
ACATCCACTA AGAGCCCAAG CGAAGATCCT CTAACCAGGA AGTCAGGGTC GTTGGTGCAG
TTCCTGTTGT ACAAGTATAA AATAAAAAAG TCCGTTACAA AGGGAGAAAT GCTGAAAATT
GTTGGCAAAA GGTTCAGGGA GCACTTCCCT GAGATCCTCA AGAAAGCCTC TGAGGGCCTC
AGTGTTGTCT TTGGCCTTGA GCTGAATAAA GTCAACCCCA ACGGCCACAC TTACACCTTC
ATCGACAAGG TAGACCTCAC TGATGAGGAA TCCCTGCTCA GTTCCTGGGA CTTTCCCAGG
AGAAAGCTTC TGATGCCTCT CCTGGGTGTG ATCTTCTTAA ATGGCAACTC AGCTACTGAG
GAAGAGATCT GGGAATTCCT GAATATGTTG GGAGTCTATG ATGGAGAGGA GCACTCAGTC
TTTGGGGAAC CCTGGAAGCT CATCACCAAA GATCTGGTGC AGGAAAAATA TCTGGAGTAC
AAGCAGGTGC CCAGCAGTGA TCCCCCACGC TTTCAATTCC TGTGGGGTCC GAGAGCCTAT
GCTGAAACCA GCAAGATGAA AGTCCTGGAG TTTTTGGCCA AGGTAAATGG TACCACCCCC
TGTGCCTTCC CAACCCATTA CGAAGAAGCT TTGAAAGATG AAGAGAAAGC CGGAGTCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

 
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