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MAGEB4 melanoma antigen family B4 [Homo sapiens (human)]

Gene Symbol MAGEB4
Entrez Gene ID 4115
Full Name melanoma antigen family B4
Synonyms CT3.6
General protein information
Preferred Names
melanoma-associated antigen B4
Names
melanoma-associated antigen B4
MAGE-B4 antigen
cancer/testis antigen family 3, member 6
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

X

Xp21.3

Summary This gene is a member of the MAGEB gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 68% sequence identity to each other. The promoters and first exons of the MAGEB genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEB genes are clustered on chromosome Xp22-p21. This gene sequence ends in the first intron of MAGEB1, another family member. This gene is expressed in testis. [provided by RefSeq, Jul 2008]. COMPLETENESS: complete on the 3' end. lac of sum
Disorder MIM:

300153

Disorder Html:





The following MAGEB4 gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MAGEB4 gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu19031 NM_002367 Homo sapiens melanoma antigen family B4 (MAGEB4), mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $379

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu19031
Accession Version NM_002367.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1041bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 08-FEB-2015
Organism Homo sapiens (human)
Product melanoma-associated antigen B4
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB056993.1, AK313769.1 and BC032852.2. This sequence is a reference standard in the RefSeqGene project. On Oct 23, 2009 this sequence version replaced gi:29171715. Summary: This gene is a member of the MAGEB gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 68% sequence identity to each other. The promoters and first exons of the MAGEB genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEB genes are clustered on chromosome Xp22-p21. This gene sequence ends in the first intron of MAGEB1, another family member. This gene is expressed in testis. [provided by RefSeq, Jul 2008]. COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGCCTCGGG GTCAGAAGAG TAAGCTCCGT GCCCGTGAGA AACGCCAGCG GACCCGTGGT 
CAGACCCAGG ATCTCAAGGT TGGTCAGCCT ACTGCAGCAG AGAAAGAAGA GTCTCCTTCC
TCTTCCTCAT CTGTTTTGAG GGATACTGCC TCCAGCTCCC TTGCTTTTGG CATTCCCCAG
GAGCCTCAGA GAGAGCCACC CACCACCTCT GCTGCTGCAG CTATGTCATG CACTGGATCT
GATAAAGGCG ACGAGAGCCA AGATGAGGAA AATGCAAGTT CCTCCCAGGC CTCAACATCC
ACTGAGAGAT CACTCAAAGA TTCTCTAACC AGGAAGACGA AGATGTTAGT GCAGTTCCTG
CTGTACAAGT ATAAAATGAA AGAGCCCACT ACAAAGGCAG AAATGCTGAA GATCATCAGC
AAAAAGTACA AGGAGCACTT CCCTGAGATC TTCAGGAAAG TCTCTCAGCG CACGGAGCTG
GTCTTTGGCC TTGCCTTGAA GGAGGTCAAC CCCACCACTC ACTCCTACAT CCTCGTCAGC
ATGCTAGGCC CCAACGATGG AAACCAGAGC AGTGCCTGGA CCCTTCCAAG GAATGGGCTT
CTGATGCCTC TACTGAGTGT GATCTTCTTA AATGGCAACT GTGCCCGTGA AGAGGAAATC
TGGGAATTCC TGAATATGCT GGGGATCTAT GATGGAAAGA GGCACCTTAT CTTTGGGGAA
CCCCGAAAGC TCATCACCCA AGATCTGGTA CAGGAAAAAT ATCTGGAATA CCAGCAGGTG
CCCAACAGTG ATCCCCCACG CTATCAATTC CTGTGGGGTC CAAGAGCTCA TGCAGAAACC
AGCAAGATGA AAGTCCTGGA GTTTTTGGCC AAGGTGAATG ACACCACCCC CAATAACTTC
CCACTGCTTT ATGAAGAGGC TTTGAGAGAT GAAGAAGAGA GAGCTGGAGC CCGGCCCAGA
GTTGCAGCCA GGCGTGGCAC TACAGCCATG ACTAGTGCGT ATTCCAGGGC CACATCCAGT
AGCTCTTCCC AACCCATGTG A
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_002358.1
CDS197..1237
Misc Feature(1)86..88(+)
Misc Feature(2)203..469(+)
Misc Feature(3)542..1051(+)
Exon (1)1..2254
Gene:MAGEB4
Gene Synonym:
Translation
Position Chain Variation Link
106 106 g, t dbSNP:187162423
121 121 a, g dbSNP:750787912
147 147 a, c, t dbSNP:199538463
161 161 c, g dbSNP:770941569
162 162 g, t dbSNP:774044365
166 166 c, t dbSNP:376209507
168 168 c, g dbSNP:768773921
171 171 a, g dbSNP:56405809
182 182 c, t dbSNP:761922811
190 190 a, g dbSNP:769844359
204 204 a, g dbSNP:773229527
214 214 a, g dbSNP:763485209
215 215 a, t dbSNP:766809466
220 220 a, g dbSNP:751888293
231 231 a, g dbSNP:759926762
240 240 a, g dbSNP:767138317
245 245 c, t dbSNP:148486223
246 246 a, g dbSNP:142718587
252 252 a, g dbSNP:144674936
261 261 c, t dbSNP:753357142
271 271 c, t dbSNP:140958735
279 279 a, g dbSNP:202212657
290 290 a, g dbSNP:745716734
305 305 a, g dbSNP:771869352
315 315 a, c dbSNP:781319230
317 317 c, t dbSNP:17853104
338 338 a, g dbSNP:267606430
339 339 a, g dbSNP:748393341
340 340 c, t dbSNP:769966655
345 345 c, g, t dbSNP:144717807
346 346 c, g dbSNP:771404409
352 352 c, t dbSNP:774913579
356 356 c, t dbSNP:759854232
360 360 c, t dbSNP:767898608
365 365 c, g dbSNP:758926054
371 371 a, c dbSNP:760433831
372 372 c, t dbSNP:763771427
375 375 a, c dbSNP:753412114
385 385 a, g dbSNP:756814506
388 388 a, g dbSNP:778757189
400 400 c, t dbSNP:757637539
402 402 c, t dbSNP:141706428
431 431 a, g dbSNP:746454846
432 432 g, t dbSNP:147091800
444 444 g, t dbSNP:746741953
445 445 c, t dbSNP:770019939
446 446 a, g dbSNP:201048812
448 448 c, t dbSNP:138311456
457 457 a, g dbSNP:184095071
458 458 -, t dbSNP:35881345
470 470 g, t dbSNP:774766874
479 479 c, t dbSNP:746406092
485 485 c, g dbSNP:772416089
486 486 c, t dbSNP:776000539
490 490 a, g dbSNP:761064104
493 493 a, g dbSNP:763898364
504 504 a, g dbSNP:776392277
506 506 a, c, t dbSNP:149213172
525 525 a, c dbSNP:143412324
533 533 a, g dbSNP:758358296
534 534 c, t dbSNP:766167581
550 550 a, g dbSNP:61744023
560 560 c, t dbSNP:754758952
571 571 a, g dbSNP:778014681
573 573 c, t dbSNP:749493494
577 577 a, g dbSNP:757375998
586 586 g, t dbSNP:142404263
589 589 a, c dbSNP:370136398
595 595 a, g dbSNP:772647582
613 613 c, t dbSNP:776127502
629 629 a, g dbSNP:747445651
636 636 c, t dbSNP:769119886
637 637 c, t dbSNP:145955448
665 665 c, t dbSNP:761557441
666 666 a, g dbSNP:764727093
669 669 c, t dbSNP:772790238
670 670 a, g dbSNP:762353238
674 674 c, t dbSNP:766365895
692 692 g, t dbSNP:751471642
694 694 a, g dbSNP:754820184
697 697 a, g dbSNP:201394701
718 718 a, c, t dbSNP:546881077
725 725 a, g dbSNP:757507580
730 730 c, t dbSNP:778945640
731 731 a, g dbSNP:146082702
738 738 c, t dbSNP:758405069
744 744 a, g dbSNP:141709716
751 751 c, t dbSNP:373465680
752 752 g, t dbSNP:17853105
754 754 c, t dbSNP:772883302
755 755 g, t dbSNP:781692865
764 764 a, g dbSNP:376364006
782 782 c, t dbSNP:146249944
797 797 c, t dbSNP:267606431
837 837 a, g dbSNP:139164773
842 842 c, g, t dbSNP:187437526
843 843 a, g dbSNP:770408937
844 844 c, t dbSNP:773806078
849 849 a, c, g dbSNP:149954634
854 854 a, g dbSNP:201965200
886 886 c, t dbSNP:760375376
901 901 c, t dbSNP:765563739
905 905 a, g dbSNP:750579962
913 913 a, g dbSNP:758644905
921 921 a, g, t dbSNP:370810015
925 925 a, g dbSNP:755553073
943 943 a, g dbSNP:781760600
946 946 a, g dbSNP:2071311
958 958 c, t dbSNP:770018442
971 971 a, c dbSNP:751763813
978 978 c, t dbSNP:748919050
982 982 a, c dbSNP:770533543
986 986 c, g dbSNP:148704670
992 992 a, c dbSNP:758990121
995 995 a, c, t dbSNP:112995221
996 996 a, g dbSNP:151222568
1003 1003 a, g dbSNP:763817266
1006 1006 c, t dbSNP:374350279
1025 1025 c, t dbSNP:746888609
1063 1063 a, g dbSNP:771045076
1071 1071 a, t dbSNP:776963174
1072 1072 g, t dbSNP:766647973
1074 1074 a, g dbSNP:751745261
1075 1075 c, t dbSNP:755102001
1078 1078 c, t dbSNP:377309173
1089 1089 a, g dbSNP:750732116
1102 1102 c, g dbSNP:2856733
1139 1139 a, g dbSNP:756600209
1140 1140 c, g dbSNP:778033888
1148 1148 c, t dbSNP:370615666
1149 1149 a, g dbSNP:756919640
1165 1165 c, t dbSNP:778525911
1166 1166 a, g dbSNP:745450971
1169 1169 c, t dbSNP:374728070
1170 1170 a, g dbSNP:145475346
1174 1174 c, g dbSNP:780387804
1179 1179 c, t dbSNP:748820679
1185 1185 c, g, t dbSNP:151086232
1192 1192 c, t dbSNP:199557000
1194 1194 a, c dbSNP:761685473
1195 1195 a, g dbSNP:149887810
1198 1198 c, t dbSNP:371492963
1204 1204 c, g dbSNP:759735478
1206 1206 c, t dbSNP:767520513
1215 1215 a, g dbSNP:752786129
1256 1256 c, t dbSNP:756586581
1261 1261 c, t dbSNP:764606307
1262 1262 a, g dbSNP:376192655
1263 1263 g, t dbSNP:182412655
1280 1280 g, t dbSNP:778577070
1286 1286 c, t dbSNP:745499345
1293 1293 c, t dbSNP:771597004
1299 1299 c, t dbSNP:773095935
1345 1345 c, t dbSNP:144882352
1347 1347 c, t dbSNP:371456344
1373 1373 a, g dbSNP:764652052
1374 1374 c, t dbSNP:770920794
1378 1378 g, t dbSNP:776373361
1512 1512 c, t dbSNP:571587034
1532 1532 c, t dbSNP:764335827
1627 1627 -, actc dbSNP:751675977
1635 1635 c, g dbSNP:762175884
1641 1641 c, t dbSNP:186948407
1688 1688 a, g dbSNP:751853154
1720 1720 a, c dbSNP:191787003
1743 1743 c, t dbSNP:184313512
1763 1763 c, t dbSNP:766925306
1770 1770 c, t dbSNP:73205834
1846 1846 -, ctc dbSNP:755475254
1925 1925 g, t dbSNP:765913922
1945 1945 a, g dbSNP:374648669
1949 1949 a, g dbSNP:193017489
1976 1976 -, t dbSNP:761859924
2011 2011 a, t dbSNP:747622501
2182 2182 c, t dbSNP:758096835

Target ORF information:

RefSeq Version NM_002367
Organism Homo sapiens (human)
Definition Homo sapiens melanoma antigen family B4 (MAGEB4), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_002367

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGCCTCGGG GTCAGAAGAG TAAGCTCCGT GCCCGTGAGA AACGCCAGCG GACCCGTGGT 
CAGACCCAGG ATCTCAAGGT TGGTCAGCCT ACTGCAGCAG AGAAAGAAGA GTCTCCTTCC
TCTTCCTCAT CTGTTTTGAG GGATACTGCC TCCAGCTCCC TTGCTTTTGG CATTCCCCAG
GAGCCTCAGA GAGAGCCACC CACCACCTCT GCTGCTGCAG CTATGTCATG CACTGGATCT
GATAAAGGCG ACGAGAGCCA AGATGAGGAA AATGCAAGTT CCTCCCAGGC CTCAACATCC
ACTGAGAGAT CACTCAAAGA TTCTCTAACC AGGAAGACGA AGATGTTAGT GCAGTTCCTG
CTGTACAAGT ATAAAATGAA AGAGCCCACT ACAAAGGCAG AAATGCTGAA GATCATCAGC
AAAAAGTACA AGGAGCACTT CCCTGAGATC TTCAGGAAAG TCTCTCAGCG CACGGAGCTG
GTCTTTGGCC TTGCCTTGAA GGAGGTCAAC CCCACCACTC ACTCCTACAT CCTCGTCAGC
ATGCTAGGCC CCAACGATGG AAACCAGAGC AGTGCCTGGA CCCTTCCAAG GAATGGGCTT
CTGATGCCTC TACTGAGTGT GATCTTCTTA AATGGCAACT GTGCCCGTGA AGAGGAAATC
TGGGAATTCC TGAATATGCT GGGGATCTAT GATGGAAAGA GGCACCTTAT CTTTGGGGAA
CCCCGAAAGC TCATCACCCA AGATCTGGTA CAGGAAAAAT ATCTGGAATA CCAGCAGGTG
CCCAACAGTG ATCCCCCACG CTATCAATTC CTGTGGGGTC CAAGAGCTCA TGCAGAAACC
AGCAAGATGA AAGTCCTGGA GTTTTTGGCC AAGGTGAATG ACACCACCCC CAATAACTTC
CCACTGCTTT ATGAAGAGGC TTTGAGAGAT GAAGAAGAGA GAGCTGGAGC CCGGCCCAGA
GTTGCAGCCA GGCGTGGCAC TACAGCCATG ACTAGTGCGT ATTCCAGGGC CACATCCAGT
AGCTCTTCCC AACCCATGTG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.