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MAGOH mago homolog, exon junction complex core component [Homo sapiens (human)]

Gene Symbol MAGOH
Entrez Gene ID 4116
Full Name mago homolog, exon junction complex core component
Synonyms MAGOH1, MAGOHA
General protein information
Preferred Names
protein mago nashi homolog
Names
protein mago nashi homolog
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

1

1p32.3

Summary Drosophila that have mutations in their mago nashi (grandchildless) gene produce progeny with defects in germplasm assembly and germline development. This gene encodes the mammalian mago nashi homolog. In mammals, mRNA expression is not limited to the germ plasm, but is expressed ubiquitously in adult tissues and can be induced by serum stimulation of quiescent fibroblasts. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

602603

Disorder Html:
CloneID RefSeq Accession Definition **Vector *Turnaround time Price
OHu17496 NM_002370 Homo sapiens mago homolog, exon junction complex core component (MAGOH), mRNA. pcDNA3.1-C-(k)DYK In stock 5-7 Starting from $99.00

*Business Day
**You may select a custom vector to replace pcDNA3.1-C-(k)DYK after clone is added to cart.



CloneID OHu17496D
Sequence Information ORF Nucleotide Sequence (Length: 441bp)
Protein sequence
SNP
Vector pcDNA3.1-C-(k)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1-C-(k)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-JUL-2015
Organism Homo sapiens (human)
Product protein mago nashi homolog
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BX283982.1, AF067173.1 and AF035940.1. On Jan 28, 2011 this sequence version replaced gi:6006021. Summary: Drosophila that have mutations in their mago nashi (grandchildless) gene produce progeny with defects in germplasm assembly and germline development. This gene encodes the mammalian mago nashi homolog. In mammals, mRNA expression is not limited to the germ plasm, but is expressed ubiquitously in adult tissues and can be induced by serum stimulation of quiescent fibroblasts. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF035940.1, BM808411.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
ATGGAGAGTG ACTTTTATCT GCGTTACTAC GTGGGGCACA AGGGCAAGTT CGGCCACGAG 
TTCCTGGAGT TTGAGTTTCG ACCGGACGGG AAGTTAAGAT ATGCCAACAA CAGCAATTAC
AAGAATGATG TCATGATCAG AAAAGAGGCT TATGTACATA AAAGCGTGAT GGAGGAACTG
AAGAGAATAA TTGACGACAG TGAAATTACC AAAGAGGATG ATGCATTGTG GCCTCCTCCT
GACCGAGTGG GCCGGCAGGA GCTTGAAATC GTCATTGGAG ATGAACACAT TTCTTTTACA
ACATCAAAAA TTGGTTCCCT TATTGATGTC AATCAATCCA AGGATCCAGA AGGCTTACGA
GTATTTTATT ATCTTGTCCA GGACCTGAAG TGTTTGGTCT TCAGTCTTAT TGGATTACAC
TTCAAGATTA AACCAATCTTA G
The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.
RefSeqNP_002361.1
CDS163..603
Misc Feature(1)61..63(+)
Misc Feature(2)163..165(+)
Misc Feature(3)172..600(+)
Misc Feature(4)193..600(+)
Misc Feature(5)193..597(+)
Misc Feature(6)199..471(+)
Misc Feature(7)202..585(+)
Misc Feature(8)247..588(+)
Misc Feature(9)358..483(+)
Exon (1)1..250
Gene:MAGOH
Gene Synonym:
Exon (2)251..309
Gene:MAGOH
Gene Synonym:
Exon (3)310..420
Gene:MAGOH
Gene Synonym:
Exon (4)421..503
Gene:MAGOH
Gene Synonym:
Exon (5)504..756
Gene:MAGOH
Gene Synonym:
Translation
Position Chain Variation Link
8 8 -, ccgggcgaagaggt dbSNP:140015267
11 11 g, t dbSNP:74686470
24 24 a, g dbSNP:568894728
34 34 a, g dbSNP:111645464
35 35 c, t dbSNP:765308630
57 57 a, g dbSNP:113851758
105 105 a, g dbSNP:558592853
112 112 a, g dbSNP:754085362
116 116 a, g dbSNP:766348180
118 118 a, c, g dbSNP:201700941
119 119 c, g dbSNP:566550176
127 127 c, t dbSNP:373348889
128 128 c, t dbSNP:751128432
130 130 -, tgg dbSNP:776284030
131 131 g, t dbSNP:369315204
132 132 -, g dbSNP:761482279
132 132 c, g dbSNP:762660187
138 138 c, g dbSNP:546730677
141 141 a, g, t dbSNP:536437660
144 144 c, t dbSNP:761033717
151 151 c, g dbSNP:375576053
156 156 c, g dbSNP:772657750
157 157 a, g dbSNP:748583764
195 195 c, g dbSNP:779093072
206 206 a, g dbSNP:112174103
237 237 a, g dbSNP:768856189
246 246 a, g dbSNP:749583136
273 273 c, t dbSNP:148806439
274 274 a, g dbSNP:199934311
276 276 c, t dbSNP:369761819
315 315 c, t dbSNP:764519975
325 325 a, g dbSNP:763619997
327 327 c, t dbSNP:776137567
344 344 a, c dbSNP:113912801
349 349 a, g dbSNP:765774176
357 357 c, t dbSNP:759547631
367 367 a, g dbSNP:776723649
372 372 c, g dbSNP:771089628
373 373 a, g dbSNP:747222044
386 386 c, t dbSNP:773037471
388 388 c, t dbSNP:368006653
407 407 a, g dbSNP:762974089
408 408 a, c dbSNP:748147829
415 415 c, t dbSNP:561502516
417 417 a, g dbSNP:768577043
432 432 a, c, t dbSNP:528481424
433 433 a, g dbSNP:749229462
436 436 a, g dbSNP:779490372
449 449 a, g dbSNP:145097978
450 450 c, t dbSNP:745315166
508 508 c, t dbSNP:367623791
543 543 a, g dbSNP:779201445
552 552 a, g dbSNP:755362534
564 564 c, t dbSNP:370758699
567 567 c, t dbSNP:745975060
591 591 g, t dbSNP:749545609
603 603 a, g dbSNP:200084732
606 606 -, t dbSNP:748336839
609 609 a, g dbSNP:780619732
610 610 c, t dbSNP:756560478
612 612 c, t dbSNP:750545788
616 616 c, t dbSNP:367804756
625 625 c, g dbSNP:757536909
629 629 a, g dbSNP:751803884
630 630 g, t dbSNP:764157200
631 631 g, t dbSNP:762822642
634 634 g, t dbSNP:775100128
635 635 g, t dbSNP:765296779
638 638 a, g dbSNP:199555808
641 641 a, t dbSNP:776329982
644 644 a, g dbSNP:770551129
646 646 a, c dbSNP:187097279
647 647 a, g dbSNP:772920165
650 650 g, t dbSNP:563888977
666 666 a, g dbSNP:540734079
677 677 a, g dbSNP:777193599
708 708 c, t dbSNP:527423382

Target ORF information:

RefSeq Version NM_002370
Organism Homo sapiens (human)
Definition Homo sapiens mago homolog, exon junction complex core component (MAGOH), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1-C-(k)DYK
NM_002370

ORF Insert Sequence:

1
61
121
181
241
301
361
421
ATGGAGAGTG ACTTTTATCT GCGTTACTAC GTGGGGCACA AGGGCAAGTT CGGCCACGAG 
TTCCTGGAGT TTGAGTTTCG ACCGGACGGG AAGTTAAGAT ATGCCAACAA CAGCAATTAC
AAGAATGATG TCATGATCAG AAAAGAGGCT TATGTACATA AAAGCGTGAT GGAGGAACTG
AAGAGAATAA TTGACGACAG TGAAATTACC AAAGAGGATG ATGCATTGTG GCCTCCTCCT
GACCGAGTGG GCCGGCAGGA GCTTGAAATC GTCATTGGAG ATGAACACAT TTCTTTTACA
ACATCAAAAA TTGGTTCCCT TATTGATGTC AATCAATCCA AGGATCCAGA AGGCTTACGA
GTATTTTATT ATCTTGTCCA GGACCTGAAG TGTTTGGTCT TCAGTCTTAT TGGATTACAC
TTCAAGATTA AACCAATCTTA G

The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.