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MAOA monoamine oxidase A [Homo sapiens (human)]

Gene Symbol MAOA
Entrez Gene ID 4128
Full Name monoamine oxidase A
Synonyms MAO-A
General protein information
Preferred Names
amine oxidase [flavin-containing] A
Names
amine oxidase [flavin-containing] A
monoamine oxidase type A
NP_000231.1
NP_001257387.1
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

X

Xp11.3

Summary This gene is one of two neighboring gene family members that encode mitochondrial enzymes which catalyze the oxidative deamination of amines, such as dopamine, norepinephrine, and serotonin. Mutation of this gene results in Brunner syndrome. This gene has also been associated with a variety of other psychiatric disorders, including antisocial behavior. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Jul 2012]. lac of sum
Disorder MIM:

309850

Disorder Html: Brunner syndrome, 300615 (3)





The following MAOA gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MAOA gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu21311 NM_000240 Homo sapiens monoamine oxidase A (MAOA), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$379
OHu14879 NM_001270458 Homo sapiens monoamine oxidase A (MAOA), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$319

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu21311
Accession Version NM_000240.3
Sequence Information ORF Nucleotide Sequence (Length: 1584bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product amine oxidase [flavin-containing] A isoform 1
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL109855.17, BC044787.1, BC008064.2 and AL020990.2. This sequence is a reference standard in the RefSeqGene project. On Jul 12, 2012 this sequence version replaced gi:33469954. Summary: This gene is one of two neighboring gene family members that encode mitochondrial enzymes which catalyze the oxidative deamination of amines, such as dopamine, norepinephrine, and serotonin. Mutation of this gene results in Brunner syndrome. This gene has also been associated with a variety of other psychiatric disorders, including antisocial behavior. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Jul 2012]. Transcript Variant: This variant (1) encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## ##Evidence-Data-START## Transcript exon combination :: BC044787.1, AK223499.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
ATGGAGAATC AAGAGAAGGC GAGTATCGCG GGCCACATGT TCGACGTAGT CGTGATCGGA 
GGTGGCATTT CAGGACTATC TGCTGCCAAA CTCTTGACTG AATATGGCGT TAGTGTTTTG
GTTTTAGAAG CTCGGGACAG GGTTGGAGGA AGAACATATA CTATAAGGAA TGAGCATGTT
GATTACGTAG ATGTTGGTGG AGCTTATGTG GGACCAACCC AAAACAGAAT CTTACGCTTG
TCTAAGGAGC TGGGCATAGA GACTTACAAA GTGAATGTCA GTGAGCGTCT CGTTCAATAT
GTCAAGGGGA AAACATATCC ATTTCGGGGC GCCTTTCCAC CAGTATGGAA TCCCATTGCA
TATTTGGATT ACAATAATCT GTGGAGGACA ATAGATAACA TGGGGAAGGA GATTCCAACT
GATGCACCCT GGGAGGCTCA ACATGCTGAC AAATGGGACA AAATGACCAT GAAAGAGCTC
ATTGACAAAA TCTGCTGGAC AAAGACTGCT AGGCGGTTTG CTTATCTTTT TGTGAATATC
AATGTGACCT CTGAGCCTCA CGAAGTGTCT GCCCTGTGGT TCTTGTGGTA TGTGAAGCAG
TGCGGGGGCA CCACTCGGAT ATTCTCTGTC ACCAATGGTG GCCAGGAACG GAAGTTTGTA
GGTGGATCTG GTCAAGTGAG CGAACGGATA ATGGACCTCC TCGGAGACCA AGTGAAGCTG
AACCATCCTG TCACTCACGT TGACCAGTCA AGTGACAACA TCATCATAGA GACGCTGAAC
CATGAACATT ATGAGTGCAA ATACGTAATT AATGCGATCC CTCCGACCTT GACTGCCAAG
ATTCACTTCA GACCAGAGCT TCCAGCAGAG AGAAACCAGT TAATTCAGCG GCTTCCAATG
GGAGCTGTCA TTAAGTGCAT GATGTATTAC AAGGAGGCCT TCTGGAAGAA GAAGGATTAC
TGTGGCTGCA TGATCATTGA AGATGAAGAT GCTCCAATTT CAATAACCTT GGATGACACC
AAGCCAGATG GGTCACTGCC TGCCATCATG GGCTTCATTC TTGCCCGGAA AGCTGATCGA
CTTGCTAAGC TACATAAGGA AATAAGGAAG AAGAAAATCT GTGAGCTCTA TGCCAAAGTG
CTGGGATCCC AAGAAGCTTT ACATCCAGTG CATTATGAAG AGAAGAACTG GTGTGAGGAG
CAGTACTCTG GGGGCTGCTA CACGGCCTAC TTCCCTCCTG GGATCATGAC TCAATATGGA
AGGGTGATTC GTCAACCCGT GGGCAGGATT TTCTTTGCGG GCACAGAGAC TGCCACAAAG
TGGAGCGGCT ACATGGAAGG GGCAGTTGAG GCTGGAGAAC GAGCAGCTAG GGAGGTCTTA
AATGGTCTCG GGAAGGTGAC CGAGAAAGAT ATCTGGGTAC AAGAACCTGA ATCAAAGGAC
GTTCCAGCGG TAGAAATCAC CCACACCTTC TGGGAAAGGA ACCTGCCCTC TGTTTCTGGC
CTGCTGAAGA TCATTGGATT TTCCACATCA GTAACTGCCC TGGGGTTTGT GCTGTACAAA
TACAAGCTCC TGCCACGGTC TTGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_000231.1
CDS1436..3019
Misc Feature(1)902..904(+)
Misc Feature(2)1436..1438(+)
Misc Feature(3)1478..2815(+)
Misc Feature(4)1487..1687(+)
Misc Feature(5)1493..1567(+)
Misc Feature(6)2438..2440(+)
Misc Feature(7)2555..2557(+)
Misc Feature(8)2651..2653(+)
Misc Feature(9)2927..2989(+)
Misc Feature(10)2993..3001(+)
Exon (1)1..1508
Gene:MAOA
Gene Synonym:
Exon (2)1509..1603
Gene:MAOA
Gene Synonym:
Exon (3)1604..1741
Gene:MAOA
Gene Synonym:
Exon (4)1742..1846
Gene:MAOA
Gene Synonym:
Exon (5)1847..1938
Gene:MAOA
Gene Synonym:
Exon (6)1939..2080
Gene:MAOA
Gene Synonym:
Exon (7)2081..2230
Gene:MAOA
Gene Synonym:
Exon (8)2231..2390
Gene:MAOA
Gene Synonym:
Exon (9)2391..2487
Gene:MAOA
Gene Synonym:
Exon (10)2488..2541
Gene:MAOA
Gene Synonym:
Exon (11)2542..2599
Gene:MAOA
Gene Synonym:
Exon (12)2600..2697
Gene:MAOA
Gene Synonym:
Exon (13)2698..2809
Gene:MAOA
Gene Synonym:
Exon (14)2810..2872
Gene:MAOA
Gene Synonym:
Exon (15)2873..5330
Gene:MAOA
Gene Synonym:
Translation
Position Chain Variation Link
23 23 a, g dbSNP:770506577
33 33 c, t dbSNP:567271355
102 102 a, g dbSNP:758921042
145 145 a, c dbSNP:769399010
150 150 a, t dbSNP:775262709
189 189 g, t dbSNP:763017181
208 208 c, t dbSNP:763786162
234 234 a, g dbSNP:112651393
244 244 c, g dbSNP:761728430
264 264 a, g dbSNP:767795523
265 265 -, gcaccagtaccc dbSNP:199760605
271 271 a, g dbSNP:750718554
294 294 a, g dbSNP:113552192
409 409 g, t dbSNP:756116482
431 431 a, g dbSNP:766547002
459 459 a, g dbSNP:754285258
528 528 a, g dbSNP:779399311
530 530 c, t dbSNP:748473177
702 702 g, t dbSNP:182564399
712 712 c, t dbSNP:758785367
762 762 c, g dbSNP:780804136
781 781 a, c dbSNP:371096478
859 859 a, g dbSNP:17436054
899 899 c, t dbSNP:769185094
1002 1002 -, ca dbSNP:766400357
1086 1086 c, t dbSNP:775126260
1191 1191 a, g dbSNP:187223433
1300 1300 c, g dbSNP:768672163
1304 1304 a, g dbSNP:373414545
1306 1306 c, t dbSNP:775531584
1339 1339 a, g dbSNP:534597592
1344 1344 c, t dbSNP:761673378
1362 1362 c, t dbSNP:192549444
1405 1405 c, g dbSNP:774554082
1409 1409 a, g dbSNP:746063415
1413 1413 -, c dbSNP:758477966
1422 1422 a, g dbSNP:772277947
1434 1434 -, g dbSNP:777977099
1448 1448 a, g dbSNP:775694295
1457 1457 a, g dbSNP:760422737
1468 1468 c, t dbSNP:763899599
1528 1528 c, t dbSNP:771174667
1543 1543 c, t dbSNP:757940669
1544 1544 a, g dbSNP:779299641
1569 1569 a, g dbSNP:745892947
1572 1572 a, g dbSNP:201519600
1594 1594 c, t dbSNP:780201424
1598 1598 a, g dbSNP:747281025
1607 1607 a, g dbSNP:759325782
1609 1609 g, t dbSNP:572229710
1617 1617 a, t dbSNP:764538239
1621 1621 c, t dbSNP:180855715
1623 1623 c, t dbSNP:754172029
1657 1657 a, g dbSNP:757566521
1669 1669 a, g dbSNP:779434656
1670 1670 c, g, t dbSNP:750916164
1691 1691 a, c dbSNP:780148935
1695 1695 a, g dbSNP:747229681
1698 1698 c, t dbSNP:768926368
1708 1708 a, g dbSNP:781408673
1720 1720 a, g dbSNP:368820082
1722 1722 a, g dbSNP:769511910
1726 1726 c, t dbSNP:773175573
1752 1752 a, t dbSNP:368236433
1753 1753 c, t dbSNP:751569965
1754 1754 a, c dbSNP:755060381
1760 1760 c, t dbSNP:140295792
1765 1765 c, t dbSNP:748344922
1766 1766 a, g dbSNP:755919316
1784 1784 a, t dbSNP:752534084
1795 1795 a, g dbSNP:749236767
1809 1809 a, g dbSNP:201799429
1820 1820 a, c dbSNP:1800464
1821 1821 a, g dbSNP:745323664
1837 1837 a, g dbSNP:771740634
1856 1856 a, g dbSNP:373044189
1861 1861 a, c dbSNP:778063152
1872 1872 c, t dbSNP:199524208
1887 1887 a, t dbSNP:757141278
1917 1917 c, t dbSNP:574432879
1925 1925 a, g dbSNP:745842135
1936 1936 a, g dbSNP:771589064
1950 1950 a, g dbSNP:58524323
1957 1957 g, t dbSNP:767634381
1975 1975 c, t dbSNP:752655267
1978 1978 c, t dbSNP:756234483
1993 1993 c, t dbSNP:764175529
1997 1997 a, g dbSNP:77698881
2000 2000 g, t dbSNP:142659522
2038 2038 c, t dbSNP:778901381
2050 2050 g, t dbSNP:750372802
2066 2066 a, g dbSNP:758333217
2070 2070 a, g dbSNP:780043965
2072 2072 g, t dbSNP:1137068
2077 2077 c, t dbSNP:746443900
2084 2084 c, t dbSNP:762184021
2085 2085 a, g dbSNP:765118799
2097 2097 c, g dbSNP:750174700
2116 2116 c, t dbSNP:758225239
2117 2117 a, g dbSNP:201785423
2120 2120 a, c dbSNP:779805250
2121 2121 a, g dbSNP:751543666
2125 2125 a, g dbSNP:754411793
2130 2130 a, t dbSNP:780726107
2137 2137 c, t dbSNP:370853887
2138 2138 a, g dbSNP:368201051
2174 2174 a, g dbSNP:777420059
2194 2194 c, t dbSNP:746172576
2195 2195 a, g dbSNP:772520550
2209 2209 a, g dbSNP:373791136
2223 2223 a, c dbSNP:377554403
2232 2232 g, t dbSNP:587777457
2239 2239 c, t dbSNP:752147192
2240 2240 a, c, g dbSNP:150176511
2251 2251 a, g dbSNP:751223564
2259 2259 c, t dbSNP:749012045
2260 2260 a, g dbSNP:138703731
2265 2265 c, t dbSNP:780527254
2271 2271 a, c dbSNP:747465837
2286 2286 a, g dbSNP:769218254
2302 2302 a, c dbSNP:756535721
2321 2321 c, t dbSNP:72554632
2325 2325 a, g dbSNP:780647851
2326 2326 g, t dbSNP:6323
2328 2328 c, t dbSNP:61730725
2368 2368 g, t dbSNP:144688481
2375 2375 g, t dbSNP:1799835
2398 2398 c, t dbSNP:769967831
2402 2402 a, t dbSNP:773395126
2443 2443 c, g dbSNP:367606788
2458 2458 a, g dbSNP:771131235
2461 2461 a, t dbSNP:1800465
2476 2476 a, c, t dbSNP:78609544
2502 2502 a, g dbSNP:779234131
2514 2514 a, g dbSNP:755359800
2516 2516 c, g dbSNP:781722252
2528 2528 a, c dbSNP:753238893
2529 2529 a, g dbSNP:756748906
2554 2554 a, c dbSNP:200913136
2563 2563 c, g dbSNP:139933657
2570 2570 a, g dbSNP:756461907
2588 2588 a, g dbSNP:778306070
2596 2596 a, g dbSNP:7065428
2606 2606 c, g dbSNP:762553962
2611 2611 c, t dbSNP:766083776
2677 2677 g, t dbSNP:774182469
2678 2678 a, t dbSNP:371491680
2683 2683 a, g dbSNP:772161607
2689 2689 a, g dbSNP:754358135
2701 2701 a, g dbSNP:377059084
2733 2733 c, t dbSNP:770610370
2734 2734 a, g dbSNP:774129169
2746 2746 a, t dbSNP:376603508
2751 2751 c, g dbSNP:764516141
2753 2753 a, g dbSNP:759809852
2761 2761 c, t dbSNP:771100973
2770 2770 g, t dbSNP:1803986
2785 2785 a, g dbSNP:762253956
2820 2820 a, g dbSNP:745388539
2824 2824 c, t dbSNP:771568228
2825 2825 a, g dbSNP:775232342
2836 2836 a, c, t dbSNP:762042526
2837 2837 a, g dbSNP:753406645
2845 2845 c, t dbSNP:1137070
2846 2846 a, c dbSNP:766439090
2849 2849 a, t dbSNP:765021585
2850 2850 g, t dbSNP:759671679
2875 2875 a, c, t dbSNP:367715125
2876 2876 a, g dbSNP:183147374
2879 2879 c, g dbSNP:767687635
2883 2883 a, c, t dbSNP:752853420
2884 2884 a, g dbSNP:377306596
2900 2900 a, g dbSNP:753629179
2928 2928 c, t dbSNP:757142968
2949 2949 c, t dbSNP:745455309
2961 2961 c, t dbSNP:147298607
2962 2962 a, t dbSNP:757822393
2972 2972 a, g dbSNP:779672283
2974 2974 c, t dbSNP:746659860
2984 2984 a, g dbSNP:140960519
2994 2994 a, g dbSNP:1800466
2996 2996 c, t dbSNP:780832453
3000 3000 a, g dbSNP:749603750
3030 3030 g, t dbSNP:771370365
3038 3038 g, t dbSNP:779381270
3048 3048 a, g dbSNP:774701462
3055 3055 a, g dbSNP:369874371
3061 3061 a, g dbSNP:772044306
3063 3063 c, g, t dbSNP:186269028
3070 3070 -, a dbSNP:746163988
3071 3071 a, t dbSNP:760850994
3264 3264 c, t dbSNP:781415569
3265 3265 c, g dbSNP:748858912
3340 3340 c, t dbSNP:745875136
3347 3347 a, g dbSNP:372972345
3426 3426 a, g dbSNP:773904709
3438 3438 c, t dbSNP:144369167
3466 3466 a, c dbSNP:780375933
3553 3553 g, t dbSNP:148377725
3626 3626 a, t dbSNP:141507018
3664 3664 c, t dbSNP:771354759
3744 3744 -, g dbSNP:763521612
3785 3785 c, t dbSNP:774747769
3843 3843 c, t dbSNP:190345937
3866 3866 -, t dbSNP:770639721
3883 3883 c, g dbSNP:777150767
3886 3886 a, g dbSNP:776273827
3902 3902 c, t dbSNP:183633096
3934 3934 c, t dbSNP:765531035
3959 3959 a, g dbSNP:775403354
3988 3988 a, g dbSNP:188559810
4062 4062 c, t dbSNP:192869160
4100 4100 a, g dbSNP:3027407
4129 4129 a, c dbSNP:763965851
4177 4177 a, g dbSNP:11544798
4248 4248 c, g dbSNP:764009837
4256 4256 a, g dbSNP:751464828
4262 4262 c, t dbSNP:183135924
4302 4302 a, g dbSNP:140387504
4480 4480 a, g dbSNP:3027408
4507 4507 c, t dbSNP:757187486
4557 4557 a, g dbSNP:767789362
4558 4558 c, t dbSNP:750680453
4581 4581 c, t dbSNP:756108128
4634 4634 a, g dbSNP:780223082
4683 4683 a, g dbSNP:767239182
4684 4684 a, t dbSNP:749737721
4696 4696 c, t dbSNP:755538277
4699 4699 c, t dbSNP:186651981
4837 4837 g, t dbSNP:748448372
4845 4845 c, t dbSNP:772443768
4849 4849 a, g dbSNP:750252602
4867 4867 a, g dbSNP:755681961
4886 4886 c, t dbSNP:779794755
4915 4915 c, t dbSNP:748724979
4916 4916 g, t dbSNP:367730729
4924 4924 a, t dbSNP:540351531
4931 4931 a, g dbSNP:191501890
4972 4972 a, g dbSNP:769213458
4986 4986 a, g dbSNP:775009822
4995 4995 a, t dbSNP:184725808
5082 5082 a, g dbSNP:764196732
5122 5122 c, t dbSNP:754592376
5238 5238 a, t dbSNP:189494708
5323 5323 a, g dbSNP:761750607

Target ORF information:

RefSeq Version NM_000240
Organism Homo sapiens (human)
Definition Homo sapiens monoamine oxidase A (MAOA), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_000240

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
ATGGAGAATC AAGAGAAGGC GAGTATCGCG GGCCACATGT TCGACGTAGT CGTGATCGGA 
GGTGGCATTT CAGGACTATC TGCTGCCAAA CTCTTGACTG AATATGGCGT TAGTGTTTTG
GTTTTAGAAG CTCGGGACAG GGTTGGAGGA AGAACATATA CTATAAGGAA TGAGCATGTT
GATTACGTAG ATGTTGGTGG AGCTTATGTG GGACCAACCC AAAACAGAAT CTTACGCTTG
TCTAAGGAGC TGGGCATAGA GACTTACAAA GTGAATGTCA GTGAGCGTCT CGTTCAATAT
GTCAAGGGGA AAACATATCC ATTTCGGGGC GCCTTTCCAC CAGTATGGAA TCCCATTGCA
TATTTGGATT ACAATAATCT GTGGAGGACA ATAGATAACA TGGGGAAGGA GATTCCAACT
GATGCACCCT GGGAGGCTCA ACATGCTGAC AAATGGGACA AAATGACCAT GAAAGAGCTC
ATTGACAAAA TCTGCTGGAC AAAGACTGCT AGGCGGTTTG CTTATCTTTT TGTGAATATC
AATGTGACCT CTGAGCCTCA CGAAGTGTCT GCCCTGTGGT TCTTGTGGTA TGTGAAGCAG
TGCGGGGGCA CCACTCGGAT ATTCTCTGTC ACCAATGGTG GCCAGGAACG GAAGTTTGTA
GGTGGATCTG GTCAAGTGAG CGAACGGATA ATGGACCTCC TCGGAGACCA AGTGAAGCTG
AACCATCCTG TCACTCACGT TGACCAGTCA AGTGACAACA TCATCATAGA GACGCTGAAC
CATGAACATT ATGAGTGCAA ATACGTAATT AATGCGATCC CTCCGACCTT GACTGCCAAG
ATTCACTTCA GACCAGAGCT TCCAGCAGAG AGAAACCAGT TAATTCAGCG GCTTCCAATG
GGAGCTGTCA TTAAGTGCAT GATGTATTAC AAGGAGGCCT TCTGGAAGAA GAAGGATTAC
TGTGGCTGCA TGATCATTGA AGATGAAGAT GCTCCAATTT CAATAACCTT GGATGACACC
AAGCCAGATG GGTCACTGCC TGCCATCATG GGCTTCATTC TTGCCCGGAA AGCTGATCGA
CTTGCTAAGC TACATAAGGA AATAAGGAAG AAGAAAATCT GTGAGCTCTA TGCCAAAGTG
CTGGGATCCC AAGAAGCTTT ACATCCAGTG CATTATGAAG AGAAGAACTG GTGTGAGGAG
CAGTACTCTG GGGGCTGCTA CACGGCCTAC TTCCCTCCTG GGATCATGAC TCAATATGGA
AGGGTGATTC GTCAACCCGT GGGCAGGATT TTCTTTGCGG GCACAGAGAC TGCCACAAAG
TGGAGCGGCT ACATGGAAGG GGCAGTTGAG GCTGGAGAAC GAGCAGCTAG GGAGGTCTTA
AATGGTCTCG GGAAGGTGAC CGAGAAAGAT ATCTGGGTAC AAGAACCTGA ATCAAAGGAC
GTTCCAGCGG TAGAAATCAC CCACACCTTC TGGGAAAGGA ACCTGCCCTC TGTTTCTGGC
CTGCTGAAGA TCATTGGATT TTCCACATCA GTAACTGCCC TGGGGTTTGT GCTGTACAAA
TACAAGCTCC TGCCACGGTC TTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu14879
Accession Version NM_001270458.1
Sequence Information ORF Nucleotide Sequence (Length: 1185bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product amine oxidase [flavin-containing] A isoform 2
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL109855.17, BC044787.1, AK293926.1, BX530072.8 and AL020990.2. Summary: This gene is one of two neighboring gene family members that encode mitochondrial enzymes which catalyze the oxidative deamination of amines, such as dopamine, norepinephrine, and serotonin. Mutation of this gene results in Brunner syndrome. This gene has also been associated with a variety of other psychiatric disorders, including antisocial behavior. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Jul 2012]. Transcript Variant: This variant (2) contains an alternate exon in the 5' UTR and uses a downstream, in-frame start codon compared to variant 1. It encodes isoform 2 which has a shorter N-terminus compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## ##Evidence-Data-START## Transcript exon combination :: AK293926.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968832 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
ATGGGGAAGG AGATTCCAAC TGATGCACCC TGGGAGGCTC AACATGCTGA CAAATGGGAC 
AAAATGACCA TGAAAGAGCT CATTGACAAA ATCTGCTGGA CAAAGACTGC TAGGCGGTTT
GCTTATCTTT TTGTGAATAT CAATGTGACC TCTGAGCCTC ACGAAGTGTC TGCCCTGTGG
TTCTTGTGGT ATGTGAAGCA GTGCGGGGGC ACCACTCGGA TATTCTCTGT CACCAATGGT
GGCCAGGAAC GGAAGTTTGT AGGTGGATCT GGTCAAGTGA GCGAACGGAT AATGGACCTC
CTCGGAGACC AAGTGAAGCT GAACCATCCT GTCACTCACG TTGACCAGTC AAGTGACAAC
ATCATCATAG AGACGCTGAA CCATGAACAT TATGAGTGCA AATACGTAAT TAATGCGATC
CCTCCGACCT TGACTGCCAA GATTCACTTC AGACCAGAGC TTCCAGCAGA GAGAAACCAG
TTAATTCAGC GGCTTCCAAT GGGAGCTGTC ATTAAGTGCA TGATGTATTA CAAGGAGGCC
TTCTGGAAGA AGAAGGATTA CTGTGGCTGC ATGATCATTG AAGATGAAGA TGCTCCAATT
TCAATAACCT TGGATGACAC CAAGCCAGAT GGGTCACTGC CTGCCATCAT GGGCTTCATT
CTTGCCCGGA AAGCTGATCG ACTTGCTAAG CTACATAAGG AAATAAGGAA GAAGAAAATC
TGTGAGCTCT ATGCCAAAGT GCTGGGATCC CAAGAAGCTT TACATCCAGT GCATTATGAA
GAGAAGAACT GGTGTGAGGA GCAGTACTCT GGGGGCTGCT ACACGGCCTA CTTCCCTCCT
GGGATCATGA CTCAATATGG AAGGGTGATT CGTCAACCCG TGGGCAGGAT TTTCTTTGCG
GGCACAGAGA CTGCCACAAA GTGGAGCGGC TACATGGAAG GGGCAGTTGA GGCTGGAGAA
CGAGCAGCTA GGGAGGTCTT AAATGGTCTC GGGAAGGTGA CCGAGAAAGA TATCTGGGTA
CAAGAACCTG AATCAAAGGA CGTTCCAGCG GTAGAAATCA CCCACACCTT CTGGGAAAGG
AACCTGCCCT CTGTTTCTGG CCTGCTGAAG ATCATTGGAT TTTCCACATC AGTAACTGCC
CTGGGGTTTG TGCTGTACAA ATACAAGCTC CTGCCACGGT CTTGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_001257387.1
CDS1943..3127
Misc Feature(1)1529..1531(+)
Misc Feature(2)2063..2923(+)
Exon (1)1..1508
Gene:MAOA
Gene Synonym:
Exon (2)1509..1616
Gene:MAOA
Gene Synonym:
Exon (3)1617..1711
Gene:MAOA
Gene Synonym:
Exon (4)1712..1849
Gene:MAOA
Gene Synonym:
Exon (5)1850..1954
Gene:MAOA
Gene Synonym:
Exon (6)1955..2046
Gene:MAOA
Gene Synonym:
Exon (7)2047..2188
Gene:MAOA
Gene Synonym:
Exon (8)2189..2338
Gene:MAOA
Gene Synonym:
Exon (9)2339..2498
Gene:MAOA
Gene Synonym:
Exon (10)2499..2595
Gene:MAOA
Gene Synonym:
Exon (11)2596..2649
Gene:MAOA
Gene Synonym:
Exon (12)2650..2707
Gene:MAOA
Gene Synonym:
Exon (13)2708..2805
Gene:MAOA
Gene Synonym:
Exon (14)2806..2917
Gene:MAOA
Gene Synonym:
Exon (15)2918..2980
Gene:MAOA
Gene Synonym:
Exon (16)2981..5438
Gene:MAOA
Gene Synonym:
Translation
Position Chain Variation Link
23 23 a, g dbSNP:770506577
33 33 c, t dbSNP:567271355
102 102 a, g dbSNP:758921042
145 145 a, c dbSNP:769399010
150 150 a, t dbSNP:775262709
189 189 g, t dbSNP:763017181
208 208 c, t dbSNP:763786162
234 234 a, g dbSNP:112651393
244 244 c, g dbSNP:761728430
264 264 a, g dbSNP:767795523
265 265 -, gcaccagtaccc dbSNP:199760605
271 271 a, g dbSNP:750718554
294 294 a, g dbSNP:113552192
409 409 g, t dbSNP:756116482
431 431 a, g dbSNP:766547002
459 459 a, g dbSNP:754285258
528 528 a, g dbSNP:779399311
530 530 c, t dbSNP:748473177
702 702 g, t dbSNP:182564399
712 712 c, t dbSNP:758785367
762 762 c, g dbSNP:780804136
781 781 a, c dbSNP:371096478
859 859 a, g dbSNP:17436054
899 899 c, t dbSNP:769185094
1002 1002 -, ca dbSNP:766400357
1086 1086 c, t dbSNP:775126260
1191 1191 a, g dbSNP:187223433
1300 1300 c, g dbSNP:768672163
1304 1304 a, g dbSNP:373414545
1306 1306 c, t dbSNP:775531584
1339 1339 a, g dbSNP:534597592
1344 1344 c, t dbSNP:761673378
1362 1362 c, t dbSNP:192549444
1405 1405 c, g dbSNP:774554082
1409 1409 a, g dbSNP:746063415
1413 1413 -, c dbSNP:758477966
1422 1422 a, g dbSNP:772277947
1434 1434 -, g dbSNP:777977099
1448 1448 a, g dbSNP:775694295
1457 1457 a, g dbSNP:760422737
1468 1468 c, t dbSNP:763899599
1532 1532 a, g dbSNP:757583016
1589 1589 a, g dbSNP:749865184
1594 1594 -, a dbSNP:779731169
1606 1606 c, g dbSNP:753470468
1636 1636 c, t dbSNP:771174667
1651 1651 c, t dbSNP:757940669
1652 1652 a, g dbSNP:779299641
1677 1677 a, g dbSNP:745892947
1680 1680 a, g dbSNP:201519600
1702 1702 c, t dbSNP:780201424
1706 1706 a, g dbSNP:747281025
1715 1715 a, g dbSNP:759325782
1717 1717 g, t dbSNP:572229710
1725 1725 a, t dbSNP:764538239
1729 1729 c, t dbSNP:180855715
1731 1731 c, t dbSNP:754172029
1765 1765 a, g dbSNP:757566521
1777 1777 a, g dbSNP:779434656
1778 1778 c, g, t dbSNP:750916164
1799 1799 a, c dbSNP:780148935
1803 1803 a, g dbSNP:747229681
1806 1806 c, t dbSNP:768926368
1816 1816 a, g dbSNP:781408673
1828 1828 a, g dbSNP:368820082
1830 1830 a, g dbSNP:769511910
1834 1834 c, t dbSNP:773175573
1860 1860 a, t dbSNP:368236433
1861 1861 c, t dbSNP:751569965
1862 1862 a, c dbSNP:755060381
1868 1868 c, t dbSNP:140295792
1873 1873 c, t dbSNP:748344922
1874 1874 a, g dbSNP:755919316
1892 1892 a, t dbSNP:752534084
1903 1903 a, g dbSNP:749236767
1917 1917 a, g dbSNP:201799429
1928 1928 a, c dbSNP:1800464
1929 1929 a, g dbSNP:745323664
1945 1945 a, g dbSNP:771740634
1964 1964 a, g dbSNP:373044189
1969 1969 a, c dbSNP:778063152
1980 1980 c, t dbSNP:199524208
1995 1995 a, t dbSNP:757141278
2025 2025 c, t dbSNP:574432879
2033 2033 a, g dbSNP:745842135
2044 2044 a, g dbSNP:771589064
2058 2058 a, g dbSNP:58524323
2065 2065 g, t dbSNP:767634381
2083 2083 c, t dbSNP:752655267
2086 2086 c, t dbSNP:756234483
2101 2101 c, t dbSNP:764175529
2105 2105 a, g dbSNP:77698881
2108 2108 g, t dbSNP:142659522
2146 2146 c, t dbSNP:778901381
2158 2158 g, t dbSNP:750372802
2174 2174 a, g dbSNP:758333217
2178 2178 a, g dbSNP:780043965
2180 2180 g, t dbSNP:1137068
2185 2185 c, t dbSNP:746443900
2192 2192 c, t dbSNP:762184021
2193 2193 a, g dbSNP:765118799
2205 2205 c, g dbSNP:750174700
2224 2224 c, t dbSNP:758225239
2225 2225 a, g dbSNP:201785423
2228 2228 a, c dbSNP:779805250
2229 2229 a, g dbSNP:751543666
2233 2233 a, g dbSNP:754411793
2238 2238 a, t dbSNP:780726107
2245 2245 c, t dbSNP:370853887
2246 2246 a, g dbSNP:368201051
2282 2282 a, g dbSNP:777420059
2302 2302 c, t dbSNP:746172576
2303 2303 a, g dbSNP:772520550
2317 2317 a, g dbSNP:373791136
2331 2331 a, c dbSNP:377554403
2340 2340 g, t dbSNP:587777457
2347 2347 c, t dbSNP:752147192
2348 2348 a, c, g dbSNP:150176511
2359 2359 a, g dbSNP:751223564
2367 2367 c, t dbSNP:749012045
2368 2368 a, g dbSNP:138703731
2373 2373 c, t dbSNP:780527254
2379 2379 a, c dbSNP:747465837
2394 2394 a, g dbSNP:769218254
2410 2410 a, c dbSNP:756535721
2429 2429 c, t dbSNP:72554632
2433 2433 a, g dbSNP:780647851
2434 2434 g, t dbSNP:6323
2436 2436 c, t dbSNP:61730725
2476 2476 g, t dbSNP:144688481
2483 2483 g, t dbSNP:1799835
2506 2506 c, t dbSNP:769967831
2510 2510 a, t dbSNP:773395126
2551 2551 c, g dbSNP:367606788
2566 2566 a, g dbSNP:771131235
2569 2569 a, t dbSNP:1800465
2584 2584 a, c, t dbSNP:78609544
2610 2610 a, g dbSNP:779234131
2622 2622 a, g dbSNP:755359800
2624 2624 c, g dbSNP:781722252
2636 2636 a, c dbSNP:753238893
2637 2637 a, g dbSNP:756748906
2662 2662 a, c dbSNP:200913136
2671 2671 c, g dbSNP:139933657
2678 2678 a, g dbSNP:756461907
2696 2696 a, g dbSNP:778306070
2704 2704 a, g dbSNP:7065428
2714 2714 c, g dbSNP:762553962
2719 2719 c, t dbSNP:766083776
2785 2785 g, t dbSNP:774182469
2786 2786 a, t dbSNP:371491680
2791 2791 a, g dbSNP:772161607
2797 2797 a, g dbSNP:754358135
2809 2809 a, g dbSNP:377059084
2841 2841 c, t dbSNP:770610370
2842 2842 a, g dbSNP:774129169
2854 2854 a, t dbSNP:376603508
2859 2859 c, g dbSNP:764516141
2861 2861 a, g dbSNP:759809852
2869 2869 c, t dbSNP:771100973
2878 2878 g, t dbSNP:1803986
2893 2893 a, g dbSNP:762253956
2928 2928 a, g dbSNP:745388539
2932 2932 c, t dbSNP:771568228
2933 2933 a, g dbSNP:775232342
2944 2944 a, c, t dbSNP:762042526
2945 2945 a, g dbSNP:753406645
2953 2953 c, t dbSNP:1137070
2954 2954 a, c dbSNP:766439090
2957 2957 a, t dbSNP:765021585
2958 2958 g, t dbSNP:759671679
2983 2983 a, c, t dbSNP:367715125
2984 2984 a, g dbSNP:183147374
2987 2987 c, g dbSNP:767687635
2991 2991 a, c, t dbSNP:752853420
2992 2992 a, g dbSNP:377306596
3008 3008 a, g dbSNP:753629179
3036 3036 c, t dbSNP:757142968
3057 3057 c, t dbSNP:745455309
3069 3069 c, t dbSNP:147298607
3070 3070 a, t dbSNP:757822393
3080 3080 a, g dbSNP:779672283
3082 3082 c, t dbSNP:746659860
3092 3092 a, g dbSNP:140960519
3102 3102 a, g dbSNP:1800466
3104 3104 c, t dbSNP:780832453
3108 3108 a, g dbSNP:749603750
3138 3138 g, t dbSNP:771370365
3146 3146 g, t dbSNP:779381270
3156 3156 a, g dbSNP:774701462
3163 3163 a, g dbSNP:369874371
3169 3169 a, g dbSNP:772044306
3171 3171 c, g, t dbSNP:186269028
3178 3178 -, a dbSNP:746163988
3179 3179 a, t dbSNP:760850994
3372 3372 c, t dbSNP:781415569
3373 3373 c, g dbSNP:748858912
3448 3448 c, t dbSNP:745875136
3455 3455 a, g dbSNP:372972345
3534 3534 a, g dbSNP:773904709
3546 3546 c, t dbSNP:144369167
3574 3574 a, c dbSNP:780375933
3661 3661 g, t dbSNP:148377725
3734 3734 a, t dbSNP:141507018
3772 3772 c, t dbSNP:771354759
3852 3852 -, g dbSNP:763521612
3893 3893 c, t dbSNP:774747769
3951 3951 c, t dbSNP:190345937
3974 3974 -, t dbSNP:770639721
3991 3991 c, g dbSNP:777150767
3994 3994 a, g dbSNP:776273827
4010 4010 c, t dbSNP:183633096
4042 4042 c, t dbSNP:765531035
4067 4067 a, g dbSNP:775403354
4096 4096 a, g dbSNP:188559810
4170 4170 c, t dbSNP:192869160
4208 4208 a, g dbSNP:3027407
4237 4237 a, c dbSNP:763965851
4285 4285 a, g dbSNP:11544798
4356 4356 c, g dbSNP:764009837
4364 4364 a, g dbSNP:751464828
4370 4370 c, t dbSNP:183135924
4410 4410 a, g dbSNP:140387504
4588 4588 a, g dbSNP:3027408
4615 4615 c, t dbSNP:757187486
4665 4665 a, g dbSNP:767789362
4666 4666 c, t dbSNP:750680453
4689 4689 c, t dbSNP:756108128
4742 4742 a, g dbSNP:780223082
4791 4791 a, g dbSNP:767239182
4792 4792 a, t dbSNP:749737721
4804 4804 c, t dbSNP:755538277
4807 4807 c, t dbSNP:186651981
4945 4945 g, t dbSNP:748448372
4953 4953 c, t dbSNP:772443768
4957 4957 a, g dbSNP:750252602
4975 4975 a, g dbSNP:755681961
4994 4994 c, t dbSNP:779794755
5023 5023 c, t dbSNP:748724979
5024 5024 g, t dbSNP:367730729
5032 5032 a, t dbSNP:540351531
5039 5039 a, g dbSNP:191501890
5080 5080 a, g dbSNP:769213458
5094 5094 a, g dbSNP:775009822
5103 5103 a, t dbSNP:184725808
5190 5190 a, g dbSNP:764196732
5230 5230 c, t dbSNP:754592376
5346 5346 a, t dbSNP:189494708
5431 5431 a, g dbSNP:761750607

Target ORF information:

RefSeq Version NM_001270458
Organism Homo sapiens (human)
Definition Homo sapiens monoamine oxidase A (MAOA), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001270458

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
ATGGGGAAGG AGATTCCAAC TGATGCACCC TGGGAGGCTC AACATGCTGA CAAATGGGAC 
AAAATGACCA TGAAAGAGCT CATTGACAAA ATCTGCTGGA CAAAGACTGC TAGGCGGTTT
GCTTATCTTT TTGTGAATAT CAATGTGACC TCTGAGCCTC ACGAAGTGTC TGCCCTGTGG
TTCTTGTGGT ATGTGAAGCA GTGCGGGGGC ACCACTCGGA TATTCTCTGT CACCAATGGT
GGCCAGGAAC GGAAGTTTGT AGGTGGATCT GGTCAAGTGA GCGAACGGAT AATGGACCTC
CTCGGAGACC AAGTGAAGCT GAACCATCCT GTCACTCACG TTGACCAGTC AAGTGACAAC
ATCATCATAG AGACGCTGAA CCATGAACAT TATGAGTGCA AATACGTAAT TAATGCGATC
CCTCCGACCT TGACTGCCAA GATTCACTTC AGACCAGAGC TTCCAGCAGA GAGAAACCAG
TTAATTCAGC GGCTTCCAAT GGGAGCTGTC ATTAAGTGCA TGATGTATTA CAAGGAGGCC
TTCTGGAAGA AGAAGGATTA CTGTGGCTGC ATGATCATTG AAGATGAAGA TGCTCCAATT
TCAATAACCT TGGATGACAC CAAGCCAGAT GGGTCACTGC CTGCCATCAT GGGCTTCATT
CTTGCCCGGA AAGCTGATCG ACTTGCTAAG CTACATAAGG AAATAAGGAA GAAGAAAATC
TGTGAGCTCT ATGCCAAAGT GCTGGGATCC CAAGAAGCTT TACATCCAGT GCATTATGAA
GAGAAGAACT GGTGTGAGGA GCAGTACTCT GGGGGCTGCT ACACGGCCTA CTTCCCTCCT
GGGATCATGA CTCAATATGG AAGGGTGATT CGTCAACCCG TGGGCAGGAT TTTCTTTGCG
GGCACAGAGA CTGCCACAAA GTGGAGCGGC TACATGGAAG GGGCAGTTGA GGCTGGAGAA
CGAGCAGCTA GGGAGGTCTT AAATGGTCTC GGGAAGGTGA CCGAGAAAGA TATCTGGGTA
CAAGAACCTG AATCAAAGGA CGTTCCAGCG GTAGAAATCA CCCACACCTT CTGGGAAAGG
AACCTGCCCT CTGTTTCTGG CCTGCTGAAG ATCATTGGAT TTTCCACATC AGTAACTGCC
CTGGGGTTTG TGCTGTACAA ATACAAGCTC CTGCCACGGT CTTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.