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MAS1 MAS1 proto-oncogene, G protein-coupled receptor [Homo sapiens (human)]

Gene Symbol MAS1
Entrez Gene ID 4142
Full Name MAS1 proto-oncogene, G protein-coupled receptor
Synonyms MAS, MGRA
General protein information
Preferred Names
proto-oncogene Mas
Names
proto-oncogene Mas
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

6

6q25.3-q26

Summary This gene encodes a class I seven-transmembrane G-protein-coupled receptor. The encoded protein is a receptor for angiotensin-(1-7) and preferentially couples to the Gq protein, activating the phospholipase C signaling pathway. The encoded protein may play a role in multiple processes including hypotension, smooth muscle relaxation and cardioprotection by mediating the effects of angiotensin-(1-7). [provided by RefSeq, May 2012]. lac of sum
Disorder MIM:

165180

Disorder Html:





The following MAS1 gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MAS1 gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu28585 NM_002377 Homo sapiens MAS1 proto-oncogene, G protein-coupled receptor (MAS1), mRNA. pcDNA3.1+/C-(K)DYK or customized vector in pcDNA3.1+/C-(K)DYK $309

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu28585
Accession Version NM_002377.2
Sequence Information ORF Nucleotide Sequence (Length: 978bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 28-JUN-2014
Organism Homo sapiens (human)
Product proto-oncogene Mas
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from M13150.1. On Oct 1, 1999 this sequence version replaced gi:4505104. Summary: This gene encodes a class I seven-transmembrane G-protein-coupled receptor. The encoded protein is a receptor for angiotensin-(1-7) and preferentially couples to the Gq protein, activating the phospholipase C signaling pathway. The encoded protein may play a role in multiple processes including hypotension, smooth muscle relaxation and cardioprotection by mediating the effects of angiotensin-(1-7). [provided by RefSeq, May 2012]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M13150.1 [ECO:0000332] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGGATGGGT CAAACGTGAC ATCATTTGTT GTTGAGGAAC CCACGAACAT CTCAACTGGC 
AGGAACGCCT CAGTCGGGAA TGCACATCGG CAAATCCCCA TCGTGCACTG GGTCATTATG
AGCATCTCCC CAGTGGGGTT TGTTGAGAAT GGGATTCTCC TCTGGTTCCT GTGCTTCCGG
ATGAGAAGAA ATCCCTTCAC TGTCTACATC ACCCACCTGT CTATCGCAGA CATCTCACTG
CTCTTCTGTA TTTTCATCTT GTCTATCGAC TATGCTTTAG ATTATGAGCT TTCTTCTGGC
CATTACTACA CAATTGTCAC ATTATCAGTG ACTTTTCTGT TTGGCTACAA CACGGGCCTC
TATCTGCTGA CGGCCATTAG TGTGGAGAGG TGCCTGTCAG TCCTTTACCC CATCTGGTAC
CGATGCCATC GCCCCAAGTA CCAGTCGGCA TTGGTCTGTG CCCTTCTGTG GGCTCTTTCT
TGCTTGGTGA CCACCATGGA GTATGTCATG TGCATCGACA GAGAAGAAGA GAGTCACTCT
CGGAATGACT GCCGAGCAGT CATCATCTTT ATAGCCATCC TGAGCTTCCT GGTCTTCACG
CCCCTCATGC TGGTGTCCAG CACCATCTTG GTCGTGAAGA TCCGGAAGAA CACGTGGGCT
TCCCATTCCT CCAAGCTTTA CATAGTCATC ATGGTCACCA TCATTATATT CCTCATCTTC
GCTATGCCCA TGAGACTCCT TTACCTGCTG TACTATGAGT ATTGGTCGAC CTTTGGGAAC
CTACACCACA TTTCCCTGCT CTTCTCCACA ATCAACAGTA GCGCCAACCC TTTCATTTAC
TTCTTTGTGG GAAGCAGTAA GAAGAAGAGA TTCAAGGAGT CCTTAAAAGT TGTTCTGACC
AGGGCTTTCA AAGATGAAAT GCAACCTCGG CGCCAGAAAG ACAATTGTAA TACGGTCACA
GTTGAGACTG TCGTCTAA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_002368.1
CDS15..992
Misc Feature(1)3..5(+)
Misc Feature(2)123..197(+)
Misc Feature(3)180..854(+)
Misc Feature(4)210..272(+)
Misc Feature(5)327..398(+)
Misc Feature(6)462..530(+)
Misc Feature(7)570..740(+)
Misc Feature(8)570..632(+)
Misc Feature(9)687..749(+)
Misc Feature(10)804..866(+)
Exon (1)1..1135
Gene:MAS1
Gene Synonym:
Translation
Position Chain Variation Link
8 8 c, t dbSNP:191384214
10 10 a, t dbSNP:760496314
26 26 a, c dbSNP:766115651
29 29 c, t dbSNP:549158090
30 30 a, g dbSNP:369549897
33 33 a, t dbSNP:778931179
43 43 c, t dbSNP:377516639
52 52 a, t dbSNP:148810084
58 58 c, t dbSNP:770001067
59 59 a, g, t dbSNP:111927070
71 71 c, t dbSNP:141410124
72 72 g, t dbSNP:757715611
80 80 c, t dbSNP:201589978
81 81 a, g dbSNP:748896741
85 85 c, t dbSNP:768348575
86 86 a, t dbSNP:773782936
87 87 a, g dbSNP:763374675
89 89 c, g, t dbSNP:375747187
90 90 a, g dbSNP:773157877
91 91 g, t dbSNP:760551394
92 92 a, g dbSNP:367923994
95 95 g, t dbSNP:535104275
98 98 a, c dbSNP:759739036
102 102 c, t dbSNP:557897610
104 104 c, g dbSNP:752756968
114 114 a, g dbSNP:758579399
116 116 c, t dbSNP:147446689
117 117 a, g, t dbSNP:752123270
119 119 a, g dbSNP:139879171
134 134 a, c, g dbSNP:564546402
135 135 a, t dbSNP:199916450
139 139 c, t dbSNP:747751092
149 149 a, g dbSNP:771585993
152 152 c, g dbSNP:772645660
162 162 a, t dbSNP:760153377
164 164 c, t dbSNP:747019196
178 178 -, g dbSNP:776070771
193 193 a, g dbSNP:770891963
201 201 a, c, g dbSNP:776343365
214 214 c, g dbSNP:764896735
218 218 c, g dbSNP:145422711
221 221 c, t dbSNP:201287436
224 224 c, t dbSNP:764272479
226 226 a, c dbSNP:751684054
239 239 c, t dbSNP:374306384
240 240 a, g dbSNP:768037685
246 246 a, g dbSNP:750856690
254 254 a, g dbSNP:147698240
257 257 c, t dbSNP:188594906
261 261 c, t dbSNP:752353579
273 273 g, t dbSNP:758044245
274 274 c, t dbSNP:367886712
275 275 g, t dbSNP:191896350
277 277 c, t dbSNP:770809893
280 280 c, t dbSNP:781217007
281 281 c, t dbSNP:745741176
282 282 a, g, t dbSNP:769642224
288 288 -, gcttta dbSNP:759077969
295 295 a, g dbSNP:755508039
301 301 a, g dbSNP:763332083
303 303 c, t dbSNP:768986845
306 306 g, t dbSNP:372604345
307 307 c, t dbSNP:762016372
314 314 c, t dbSNP:767448750
318 318 g, t dbSNP:139649334
337 337 c, t dbSNP:75396648
343 343 c, t dbSNP:541092772
346 346 c, t dbSNP:761022711
358 358 a, g dbSNP:149942969
359 359 a, c dbSNP:754192055
365 365 c, t dbSNP:371805366
367 367 c, t dbSNP:145079703
368 368 a, g dbSNP:751168993
371 371 c, t dbSNP:756810150
373 373 g, t dbSNP:780506777
377 377 c, t dbSNP:745819582
382 382 c, t dbSNP:149100513
383 383 c, g dbSNP:780051704
385 385 c, t dbSNP:142220585
386 386 a, g dbSNP:768531368
388 388 c, t dbSNP:532916357
389 389 c, t dbSNP:761885116
395 395 c, g, t dbSNP:763695360
401 401 c, g dbSNP:773163149
404 404 c, g dbSNP:761306044
407 407 a, c dbSNP:145130069
416 416 c, t dbSNP:140242572
435 435 c, t dbSNP:759921715
444 444 c, t dbSNP:765532855
445 445 a, g dbSNP:753527518
446 446 c, t dbSNP:756790658
448 448 c, t dbSNP:375732408
454 454 a, g dbSNP:749886003
460 460 c, t dbSNP:747248947
461 461 a, g dbSNP:190132211
467 467 g, t dbSNP:749189737
468 468 g, t dbSNP:754835270
477 477 c, t dbSNP:145329855
486 486 a, g dbSNP:748472255
489 489 c, t dbSNP:772173297
494 494 g, t dbSNP:773393107
506 506 a, c dbSNP:747032500
511 511 c, t dbSNP:201189349
520 520 a, c, t dbSNP:765383320
522 522 a, t dbSNP:765587878
523 523 c, t dbSNP:775711708
530 530 c, t dbSNP:201944237
543 543 g, t dbSNP:767054325
546 546 a, g dbSNP:137950570
555 555 c, t dbSNP:375222120
556 556 a, g dbSNP:755717219
567 567 c, t dbSNP:201984343
568 568 a, g dbSNP:141043165
571 571 c, t dbSNP:754960908
576 576 a, c dbSNP:778907593
586 586 c, t dbSNP:747870183
595 595 c, t dbSNP:758684185
605 605 c, g dbSNP:777885616
613 613 c, t dbSNP:138993417
614 614 a, g dbSNP:771015772
615 615 c, t dbSNP:750358048
617 617 c, t dbSNP:758290773
629 629 a, g dbSNP:746443312
637 637 a, c dbSNP:770273965
639 639 a, g, t dbSNP:138897768
644 644 a, g dbSNP:764479610
645 645 a, g dbSNP:772752748
647 647 c, t dbSNP:220721
648 648 a, g dbSNP:528603241
657 657 c, t dbSNP:373003570
658 658 a, g dbSNP:571309056
659 659 a, g dbSNP:765050520
664 664 a, g dbSNP:546261223
667 667 c, t dbSNP:752636957
668 668 a, g dbSNP:758145350
670 670 c, g dbSNP:138263796
677 677 c, g dbSNP:181740963
692 692 g, t dbSNP:187231524
696 696 a, g dbSNP:11968301
705 705 a, c dbSNP:745928534
706 706 g, t dbSNP:377184807
706 706 -, t dbSNP:35280463
709 709 c, t dbSNP:780457504
714 714 a, g dbSNP:368888097
717 717 a, g dbSNP:749754534
722 722 a, g dbSNP:768906782
734 734 c, t dbSNP:774772519
735 735 a, g dbSNP:760460450
737 737 a, t dbSNP:770682262
739 739 c, t dbSNP:142248825
748 748 a, g dbSNP:759144768
749 749 a, g, t dbSNP:764750635
750 750 c, t dbSNP:762886071
752 752 c, t dbSNP:566846804
758 758 c, t dbSNP:763866112
761 761 -, gctg dbSNP:764768505
766 766 a, g dbSNP:751344876
768 768 -, tatgagtat dbSNP:774985560
769 769 a, g dbSNP:147267209
775 775 a, g dbSNP:769799252
776 776 g, t dbSNP:781363330
780 780 c, t dbSNP:750604816
781 781 c, t dbSNP:373119084
782 782 a, g dbSNP:201516660
788 788 g, t dbSNP:377705823
791 791 a, g dbSNP:750404972
794 794 a, c dbSNP:749826584
802 802 a, g dbSNP:769192343
805 805 c, g, t dbSNP:534430098
809 809 c, t dbSNP:772522241
815 815 c, t dbSNP:148754116
816 816 a, t dbSNP:759202947
818 818 a, c dbSNP:749572845
823 823 c, g dbSNP:769196974
825 825 a, g dbSNP:371361677
832 832 a, g dbSNP:762860063
836 836 c, t dbSNP:145623509
837 837 a, g dbSNP:142353056
841 841 a, g dbSNP:774787731
858 858 c, t dbSNP:549120687
859 859 c, t dbSNP:377679974
862 862 a, t dbSNP:756355062
868 868 g, t dbSNP:766427290
883 883 a, g dbSNP:753929998
895 895 c, t dbSNP:139579440
901 901 a, t dbSNP:779591360
913 913 a, c, t dbSNP:748613074
914 914 c, g, t dbSNP:778220861
918 918 a, g dbSNP:149736346
923 923 a, c dbSNP:769476795
924 924 a, g dbSNP:774914253
925 925 a, g dbSNP:748801784
927 927 a, g dbSNP:768013492
931 931 a, g dbSNP:774294518
934 934 c, g, t dbSNP:370639629
938 938 a, g dbSNP:373837634
942 942 c, t dbSNP:772577864
945 945 c, t dbSNP:146766270
946 946 a, g dbSNP:140222197
951 951 a, c dbSNP:755104780
952 952 a, t dbSNP:765347516
967 967 c, t dbSNP:148082809
968 968 a, g dbSNP:758973222
972 972 a, g dbSNP:778343545
975 975 a, g dbSNP:747381298
976 976 a, c, t dbSNP:144013270
981 981 a, g dbSNP:779788839
983 983 a, t dbSNP:146451067
986 986 c, t dbSNP:372960404
987 987 a, g dbSNP:149048594
989 989 c, g dbSNP:748140047
1002 1002 c, g dbSNP:771974481
1008 1008 c, t dbSNP:112564811
1016 1016 a, c dbSNP:369982265
1021 1021 c, t dbSNP:760547714
1026 1026 a, g dbSNP:542883049
1033 1033 a, g dbSNP:776922195
1036 1036 a, c dbSNP:759606731
1038 1038 -, t dbSNP:762722406
1044 1044 c, g dbSNP:765483299
1070 1070 a, g dbSNP:189490097
1110 1110 g, t dbSNP:775889551

Target ORF information:

RefSeq Version NM_002377
Organism Homo sapiens (human)
Definition Homo sapiens MAS1 proto-oncogene, G protein-coupled receptor (MAS1), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_002377

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGGATGGGT CAAACGTGAC ATCATTTGTT GTTGAGGAAC CCACGAACAT CTCAACTGGC 
AGGAACGCCT CAGTCGGGAA TGCACATCGG CAAATCCCCA TCGTGCACTG GGTCATTATG
AGCATCTCCC CAGTGGGGTT TGTTGAGAAT GGGATTCTCC TCTGGTTCCT GTGCTTCCGG
ATGAGAAGAA ATCCCTTCAC TGTCTACATC ACCCACCTGT CTATCGCAGA CATCTCACTG
CTCTTCTGTA TTTTCATCTT GTCTATCGAC TATGCTTTAG ATTATGAGCT TTCTTCTGGC
CATTACTACA CAATTGTCAC ATTATCAGTG ACTTTTCTGT TTGGCTACAA CACGGGCCTC
TATCTGCTGA CGGCCATTAG TGTGGAGAGG TGCCTGTCAG TCCTTTACCC CATCTGGTAC
CGATGCCATC GCCCCAAGTA CCAGTCGGCA TTGGTCTGTG CCCTTCTGTG GGCTCTTTCT
TGCTTGGTGA CCACCATGGA GTATGTCATG TGCATCGACA GAGAAGAAGA GAGTCACTCT
CGGAATGACT GCCGAGCAGT CATCATCTTT ATAGCCATCC TGAGCTTCCT GGTCTTCACG
CCCCTCATGC TGGTGTCCAG CACCATCTTG GTCGTGAAGA TCCGGAAGAA CACGTGGGCT
TCCCATTCCT CCAAGCTTTA CATAGTCATC ATGGTCACCA TCATTATATT CCTCATCTTC
GCTATGCCCA TGAGACTCCT TTACCTGCTG TACTATGAGT ATTGGTCGAC CTTTGGGAAC
CTACACCACA TTTCCCTGCT CTTCTCCACA ATCAACAGTA GCGCCAACCC TTTCATTTAC
TTCTTTGTGG GAAGCAGTAA GAAGAAGAGA TTCAAGGAGT CCTTAAAAGT TGTTCTGACC
AGGGCTTTCA AAGATGAAAT GCAACCTCGG CGCCAGAAAG ACAATTGTAA TACGGTCACA
GTTGAGACTG TCGTCTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.