The following MIF gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MIF gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
||ORF Nucleotide Sequence (Length: 348bp)
||pcDNA3.1+/C-(K)DYK or customized vector
|Tag on pcDNA3.1+/C-(K)DYK
||C terminal DYKDDDDK tags
|ORF Insert Method
||CloneEZ® Seamless cloning technology
||Homo sapiens (human)
||macrophage migration inhibitory factor
||REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from L19686.1.
This sequence is a reference standard in the RefSeqGene project.
Summary: This gene encodes a lymphokine involved in cell-mediated
immunity, immunoregulation, and inflammation. It plays a role in
the regulation of macrophage function in host defense through the
suppression of anti-inflammatory effects of glucocorticoids. This
lymphokine and the JAB1 protein form a complex in the cytosol near
the peripheral plasma membrane, which may indicate an additional
role in integrin signaling pathways. [provided by RefSeq, Jul
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
Transcript exon combination :: BU599051.1, BC022414.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
COMPLETENESS: complete on the 3' end.