||ORF Nucleotide Sequence (Length: 348bp)
||pcDNA3.1-C-(k)DYK or customized vector
|Tag on pcDNA3.1-C-(k)DYK
||C terminal DYKDDDDK tags
|ORF Insert Method
||CloneEZ® Seamless cloning technology
||Homo sapiens (human)
||macrophage migration inhibitory factor
||REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from L19686.1.
This sequence is a reference standard in the RefSeqGene project.
Summary: This gene encodes a lymphokine involved in cell-mediated
immunity, immunoregulation, and inflammation. It plays a role in
the regulation of macrophage function in host defense through the
suppression of anti-inflammatory effects of glucocorticoids. This
lymphokine and the JAB1 protein form a complex in the cytosol near
the peripheral plasma membrane, which may indicate an additional
role in integrin signaling pathways. [provided by RefSeq, Jul
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
Transcript exon combination :: BU599051.1, BC022414.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
COMPLETENESS: complete on the 3' end.