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CXCL9 cDNA ORF clone, Homo sapiens (human)

Gene Symbol CXCL9
Entrez Gene ID 4283
Full Name chemokine (C-X-C motif) ligand 9
Synonyms CMK, Humig, MIG, SCYB9, crg-10
General protein information
Preferred Names
C-X-C motif chemokine 9
Names
C-X-C motif chemokine 9
small-inducible cytokine B9
gamma-interferon-induced monokine
monokine induced by gamma interferon
monokine induced by interferon-gamma
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

4

4q21

Summary This antimicrobial gene encodes a protein thought to be involved in T cell trafficking. The encoded protein binds to C-X-C motif chemokine 3 and is a chemoattractant for lymphocytes but not for neutrophils. [provided by RefSeq, Sep 2014]. lac of sum
Disorder MIM:

601704


mRNA and Protein(s)

mRNA Protein Name
NM_002416 NP_002407 C-X-C motif chemokine 9 precursor



Homo sapiens (human) CXCL9 NP_002407.1
Pan troglodytes (chimpanzee) CXCL9 XP_526582.1
Macaca mulatta (Rhesus monkey) CXCL9 NP_001028108.1
Bos taurus (cattle) CXCL9 NP_001106643.1


GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following CXCL9 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CXCL9 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu26807
NM_002416 Homo sapiens chemokine (C-X-C motif) ligand 9 (CXCL9), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$49.50-$69.30
$99.00
Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
5 or more Clone 50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu26807
Clone ID Related Accession (Same CDS sequence) NM_002416
Accession Version NM_002416.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 378bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product C-X-C motif chemokine 9 precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB141449.1, X72755.1 and BC042178.1. On Oct 1, 2014 this sequence version replaced gi:4505186. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##RefSeq-Attributes-START## Protein has antimicrobial activity :: PMID: 12949249 ##RefSeq-Attributes-END## ##Evidence-Data-START## Transcript exon combination :: BC042178.1, BC063122.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
ATGAAGAAAA GTGGTGTTCT TTTCCTCTTG GGCATCATCT TGCTGGTTCT GATTGGAGTG 
CAAGGAACCC CAGTAGTGAG AAAGGGTCGC TGTTCCTGCA TCAGCACCAA CCAAGGGACT
ATCCACCTAC AATCCTTGAA AGACCTTAAA CAATTTGCCC CAAGCCCTTC CTGCGAGAAA
ATTGAAATCA TTGCTACACT GAAGAATGGA GTTCAAACAT GTCTAAACCC AGATTCAGCA
GATGTGAAGG AACTGATTAA AAAGTGGGAG AAACAGGTCA GCCAAAAGAA AAAGCAAAAG
AATGGGAAAA AACATCAAAA AAAGAAAGTT CTGAAAGTTC GAAAATCTCA ACGTTCTCGT
CAAAAGAAGA CTACATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_002407.1
CDS75..452
Misc Feature(1)144..146(+)
Misc Feature(2)156..344(+)
Misc Feature(3)156..326(+)
Misc Feature(4)156..164(+)
Misc Feature(5)159..344(+)
Misc Feature(6)159..290(+)
Misc Feature(7)162..173(+)
Misc Feature(8)168..212(+)
Misc Feature(9)174..293(+)
Misc Feature(10)198..338(+)
Misc Feature(11)204..290(+)
Misc Feature(12)210..344(+)
Misc Feature(13)237..245(+)
Misc Feature(14)237..245(+)
Misc Feature(15)276..284(+)
Exon (1)1..138
Gene:CXCL9
Gene Synonym:
Exon (2)139..265
Gene:CXCL9
Gene Synonym:
Exon (3)266..350
Gene:CXCL9
Gene Synonym:
Exon (4)351..2708
Gene:CXCL9
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_002416
Organism Homo sapiens (human)
Definition Homo sapiens chemokine (C-X-C motif) ligand 9 (CXCL9), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_002416

ORF Insert Sequence:

1
61
121
181
241
301
361
ATGAAGAAAA GTGGTGTTCT TTTCCTCTTG GGCATCATCT TGCTGGTTCT GATTGGAGTG 
CAAGGAACCC CAGTAGTGAG AAAGGGTCGC TGTTCCTGCA TCAGCACCAA CCAAGGGACT
ATCCACCTAC AATCCTTGAA AGACCTTAAA CAATTTGCCC CAAGCCCTTC CTGCGAGAAA
ATTGAAATCA TTGCTACACT GAAGAATGGA GTTCAAACAT GTCTAAACCC AGATTCAGCA
GATGTGAAGG AACTGATTAA AAAGTGGGAG AAACAGGTCA GCCAAAAGAA AAAGCAAAAG
AATGGGAAAA AACATCAAAA AAAGAAAGTT CTGAAAGTTC GAAAATCTCA ACGTTCTCGT
CAAAAGAAGA CTACATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

Higher levels of circulating CXCL-9 and CXCL-11 in euthyroid women with autoimmune thyroiditis and recurrent spontaneous abortions
Gynecol. Endocrinol. 30 (2), 157-160 (2014)
Aktas A, Berberoglu Z, Fidan Y, Yazici AC, Koc G, Aral Y, Ademoglu E, Bekdemir H and Alphan Z.


book

Plasma CXCL9 elevations correlate with chronic GVHD diagnosis
Blood 123 (5), 786-793 (2014)
Kitko CL, Levine JE, Storer BE, Chai X, Fox DA, Braun TM, Couriel DR, Martin PJ, Flowers ME, Hansen JA, Chang L, Conlon M, Fiema BJ, Morgan R, Pongtornpipat P, Lamiman K, Ferrara JL, Lee SJ and Paczesny S.


book

CXC chemokines CXCL1, CXCL9, CXCL10 and CXCL12 are variably expressed in patients with sickle cell disease and carriers: are they predictive tools for disease complications?
Clin. Lab. 60 (1), 99-104 (2014)
Ostadebrahimi H, Jamali Z, Nazari M, Bahri M, Farahmandnia Z, Khandany BK, Taheri M, Khorramdelazad H, Hakimizadeh E, Zaker F, Rezaeian M and Hassanshahi G.


book

Serum CXCL9 levels are associated with tumor progression and treatment outcome in patients with nasopharyngeal carcinoma
PLoS ONE 8 (11), E80052 (2013)
Hsin LJ, Kao HK, Chen IH, Tsang NM, Hsu CL, Liu SC, Chang YS and Chang KP.


book

CXCL9 associated with sustained virological response in chronic hepatitis B patients receiving peginterferon alfa-2a therapy: a pilot study
PLoS ONE 8 (10), E76798 (2013)
Lee IC, Huang YH, Su CW, Wang YJ, Huo TI, Lee KC and Lin HC.


book

Many chemokines including CCL20/MIP-3alpha display antimicrobial activity
J. Leukoc. Biol. 74 (3), 448-455 (2003)
Yang D, Chen Q, Hoover DM, Staley P, Tucker KD, Lubkowski J and Oppenheim JJ.


book

Human Mig chemokine: biochemical and functional characterization
J. Exp. Med. 182 (5), 1301-1314 (1995)
Liao F, Rabin RL, Yannelli JR, Koniaris LG, Vanguri P and Farber JM.


book

HuMig: a new human member of the chemokine family of cytokines
Biochem. Biophys. Res. Commun. 192 (1), 223-230 (1993)
Farber JM.


book

A macrophage mRNA selectively induced by gamma-interferon encodes a member of the platelet factor 4 family of cytokines
Proc. Natl. Acad. Sci. U.S.A. 87 (14), 5238-5242 (1990)
Farber JM.


book

Presence of three distinct molecular species of Gi protein alpha subunit. Structure of rat cDNAs and human genomic DNAs
J. Biol. Chem. 263 (14), 6656-6664 (1988)
Itoh H, Toyama R, Kozasa T, Tsukamoto T, Matsuoka M and Kaziro Y.


 
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