||ORF Nucleotide Sequence (Length: 804bp)
||pcDNA3.1-C-(k)DYK or customized vector
|Tag on pcDNA3.1-C-(k)DYK
||C terminal DYKDDDDK tags
|ORF Insert Method
||CloneEZ® Seamless cloning technology
||Homo sapiens (human)
||homeobox protein MSX-2
||REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from AL552909.3, AC117531.2,
W38629.1 and D89377.1.
This sequence is a reference standard in the RefSeqGene project.
On Jan 5, 2006 this sequence version replaced gi:27886556.
Summary: This gene encodes a member of the muscle segment homeobox
gene family. The encoded protein is a transcriptional repressor
whose normal activity may establish a balance between survival and
apoptosis of neural crest-derived cells required for proper
craniofacial morphogenesis. The encoded protein may also have a
role in promoting cell growth under certain conditions and may be
an important target for the RAS signaling pathways. Mutations in
this gene are associated with parietal foramina 1 and
craniosynostosis type 2. [provided by RefSeq, Jul 2008].
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
Transcript exon combination :: D89377.1, D26145.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
COMPLETENESS: complete on the 3' end.