The following MSX2 gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MSX2 gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
||ORF Nucleotide Sequence (Length: 804bp)
||pcDNA3.1+/C-(K)DYK or customized vector
|Tag on pcDNA3.1+/C-(K)DYK
||C terminal DYKDDDDK tags
|ORF Insert Method
||CloneEZ® Seamless cloning technology
||Homo sapiens (human)
||homeobox protein MSX-2
||REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from AL552909.3, AC117531.2,
W38629.1 and D89377.1.
This sequence is a reference standard in the RefSeqGene project.
On Jan 5, 2006 this sequence version replaced gi:27886556.
Summary: This gene encodes a member of the muscle segment homeobox
gene family. The encoded protein is a transcriptional repressor
whose normal activity may establish a balance between survival and
apoptosis of neural crest-derived cells required for proper
craniofacial morphogenesis. The encoded protein may also have a
role in promoting cell growth under certain conditions and may be
an important target for the RAS signaling pathways. Mutations in
this gene are associated with parietal foramina 1 and
craniosynostosis type 2. [provided by RefSeq, Jul 2008].
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
Transcript exon combination :: D89377.1, D26145.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
COMPLETENESS: complete on the 3' end.