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MYH7 cDNA ORF clone, Homo sapiens (human)

Gene Symbol MYH7
Entrez Gene ID 4625
Full Name myosin, heavy chain 7, cardiac muscle, beta
Synonyms CMD1S, CMH1, MPD1, MYHCB, SPMD, SPMM
General protein information
Preferred Names
myosin-7
Names
myosin-7
myHC-beta
myhc-slow
myopathy, distal 1
myosin heavy chain 7
beta-myosin heavy chain
myosin heavy chain (AA 1-96)
myosin heavy chain slow isoform
rhabdomyosarcoma antigen MU-RMS-40.7A
myosin heavy chain, cardiac muscle beta isoform
myosin, heavy polypeptide 7, cardiac muscle, beta
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

14

14q12

Summary Muscle myosin is a hexameric protein containing 2 heavy chain subunits, 2 alkali light chain subunits, and 2 regulatory light chain subunits. This gene encodes the beta (or slow) heavy chain subunit of cardiac myosin. It is expressed predominantly in normal human ventricle. It is also expressed in skeletal muscle tissues rich in slow-twitch type I muscle fibers. Changes in the relative abundance of this protein and the alpha (or fast) heavy subunit of cardiac myosin correlate with the contractile velocity of cardiac muscle. Its expression is also altered during thyroid hormone depletion and hemodynamic overloading. Mutations in this gene are associated with familial hypertrophic cardiomyopathy, myosin storage myopathy, dilated cardiomyopathy, and Laing early-onset distal myopathy. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

160760

Disorder Html: Cardiomyopathy, familial hypertrophic, 1, 192600 (3); Cardiomyopathy,

mRNA and Protein(s)

mRNA Protein Name
NM_000257 NP_000248 myosin-7



Homo sapiens (human) MYH7 NP_000248.2
Pan troglodytes (chimpanzee) MYH7 XP_001150786.3
Canis lupus familiaris (dog) MYH7 NP_001107183.1
Bos taurus (cattle) MYH7 NP_777152.1
Mus musculus (house mouse) Myh7 NP_542766.1
Rattus norvegicus (Norway rat) Myh7 NP_058936.1
Gallus gallus (chicken) MYH7 NP_001001302.1
Danio rerio (zebrafish) vmhc NP_001106204.1
Danio rerio (zebrafish) smyhc1 NP_001018343.1
Danio rerio (zebrafish) smyhc3 NP_001129995.1
Danio rerio (zebrafish) vmhcl NP_001070932.2
Danio rerio (zebrafish) si:ch211-24n20.3 XP_001923213.1
Danio rerio (zebrafish) smyhc2 NP_001096096.2
Danio rerio (zebrafish) LOC100329670 XP_002666777.2
Danio rerio (zebrafish) LOC100329748 XP_002666778.1
Danio rerio (zebrafish) LOC567740 XP_696132.3
Danio rerio (zebrafish) LOC100329813 XP_002666779.1
Drosophila melanogaster (fruit fly) Mhc NP_001246049.1
Xenopus (Silurana) tropicalis (western clawed frog) myh7 XP_002939061.1


GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following MYH7 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MYH7 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu28301 NM_000257 Homo sapiens myosin, heavy chain 7, cardiac muscle, beta (MYH7), mRNA. pcDNA3.1+/C-(K)DYK or customized vector 22 $923.30
$1319.00
Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
5 or more Clone 50% OFF
All Other ORF Clones
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu28301
Clone ID Related Accession (Same CDS sequence) NM_000257
Accession Version NM_000257.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 5808bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product myosin-7
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BF834726.1, EU747717.1, M58018.1 and BC112173.1. On or before Jun 20, 2014 this sequence version replaced gi:530403846, gi:115496168. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: EU747717.1, M58018.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA962337, SAMEA962346 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
3481
3541
3601
3661
3721
3781
3841
3901
3961
4021
4081
4141
4201
4261
4321
4381
4441
4501
4561
4621
4681
4741
4801
4861
4921
4981
5041
5101
5161
5221
5281
5341
5401
5461
5521
5581
5641
5701
5761
ATGGGAGATT CGGAGATGGC AGTCTTTGGG GCTGCCGCCC CCTACCTGCG CAAGTCAGAG 
AAGGAGCGGC TAGAAGCGCA GACCAGGCCT TTTGACCTCA AGAAGGATGT CTTCGTGCCT
GATGACAAAC AGGAGTTTGT CAAGGCCAAG ATCGTGTCTC GAGAGGGTGG CAAAGTCACT
GCCGAGACCG AGTATGGCAA GACAGTGACC GTGAAGGAGG ACCAGGTGAT GCAGCAGAAC
CCACCCAAGT TCGACAAAAT CGAGGACATG GCCATGCTGA CCTTCCTGCA TGAGCCCGCG
GTGCTCTACA ACCTCAAGGA TCGCTACGGC TCCTGGATGA TCTACACCTA CTCGGGCCTC
TTCTGTGTCA CCGTCAACCC TTACAAGTGG CTGCCGGTGT ACACTCCTGA GGTGGTGGCT
GCCTACCGGG GCAAGAAGAG GAGCGAGGCC CCGCCCCACA TCTTCTCCAT CTCCGACAAC
GCCTATCAGT ACATGCTGAC AGACAGAGAA AACCAGTCCA TCCTGATCAC CGGAGAATCC
GGAGCAGGGA AGACAGTCAA CACCAAGAGG GTCATCCAGT ACTTTGCTGT TATTGCAGCC
ATTGGGGACC GCAGCAAGAA GGACCAGAGC CCGGGCAAGG GCACCCTGGA GGACCAGATC
ATCCAGGCCA ACCCTGCTCT GGAGGCCTTT GGCAATGCCA AGACCGTCCG GAACGACAAC
TCCTCCCGCT TCGGGAAATT CATTCGAATT CATTTTGGGG CAACAGGAAA GTTGGCATCT
GCAGACATAG AGACCTATCT TCTGGAAAAA TCCAGAGTTA TTTTCCAGCT GAAAGCAGAG
AGAGATTATC ACATTTTCTA CCAAATCCTG TCTAACAAAA AGCCTGAGCT GCTGGACATG
CTGCTGATCA CCAACAACCC CTACGATTAT GCATTCATCT CCCAAGGAGA GACCACCGTG
GCCTCCATTG ATGACGCTGA GGAGCTCATG GCCACTGATA ACGCTTTTGA TGTGCTGGGC
TTCACTTCAG AGGAGAAAAA CTCCATGTAT AAGCTGACAG GCGCCATCAT GCACTTTGGA
AACATGAAGT TCAAGCTGAA GCAGCGGGAG GAGCAGGCGG AGCCAGACGG CACTGAAGAG
GCTGACAAGT CTGCCTACCT CATGGGGCTG AACTCAGCCG ACCTGCTCAA GGGGCTGTGC
CACCCTCGGG TGAAAGTGGG CAATGAGTAC GTCACCAAGG GGCAGAATGT CCAGCAGGTG
ATATATGCCA CTGGGGCACT GGCCAAGGCA GTGTATGAGA GGATGTTCAA CTGGATGGTG
ACGCGCATCA ATGCCACCCT GGAGACCAAG CAGCCACGCC AGTACTTCAT AGGAGTCCTG
GACATCGCTG GCTTCGAGAT CTTCGATTTC AACAGCTTTG AGCAGCTCTG CATCAACTTC
ACCAACGAGA AGCTGCAGCA GTTCTTCAAC CACCACATGT TTGTGCTGGA GCAGGAGGAG
TACAAGAAGG AGGGCATCGA GTGGACATTC ATTGACTTTG GCATGGACCT GCAGGCCTGC
ATTGACCTCA TCGAGAAGCC CATGGGCATC ATGTCCATCC TGGAAGAGGA GTGCATGTTC
CCCAAGGCCA CCGACATGAC CTTCAAGGCC AAGCTGTTTG ACAACCACCT GGGCAAATCC
GCCAACTTCC AGAAGCCACG CAATATCAAG GGGAAGCCTG AAGCCCACTT CTCCCTGATC
CACTATGCCG GCATCGTGGA CTACAACATC ATTGGCTGGC TGCAGAAGAA CAAGGATCCT
CTCAATGAGA CTGTCGTGGG CTTGTATCAG AAGTCTTCCC TCAAGCTGCT CAGCACCCTG
TTTGCCAACT ATGCTGGGGC TGATGCGCCT ATTGAGAAGG GCAAAGGCAA GGCCAAGAAA
GGCTCGTCCT TTCAGACTGT GTCAGCTCTG CACAGGGAAA ATCTGAACAA GCTGATGACC
AACTTGCGCT CCACCCATCC CCACTTTGTA CGTTGTATCA TCCCTAATGA GACAAAGTCT
CCAGGGGTGA TGGACAACCC CCTGGTCATG CACCAGCTGC GCTGCAATGG TGTGCTGGAG
GGCATCCGCA TCTGCAGGAA AGGCTTCCCC AACCGCATCC TCTACGGGGA CTTCCGGCAG
AGGTATCGCA TCCTGAACCC AGCGGCCATC CCTGAGGGAC AGTTCATTGA TAGCAGGAAG
GGGGCAGAGA AGCTGCTCAG CTCCCTGGAC ATTGATCACA ACCAGTACAA GTTTGGCCAC
ACCAAGGTGT TCTTCAAGGC CGGGCTGCTG GGGCTGCTGG AGGAAATGAG GGACGAGAGG
CTGAGCCGCA TCATCACGCG TATCCAGGCC CAGTCCCGAG GTGTGCTCGC CAGAATGGAG
TACAAAAAGC TGCTGGAACG TAGAGACTCC CTGCTGGTAA TCCAGTGGAA CATTCGGGCC
TTCATGGGGG TCAAGAATTG GCCCTGGATG AAGCTCTACT TCAAGATCAA GCCGCTGCTG
AAGAGTGCAG AAAGAGAGAA GGAGATGGCC TCCATGAAGG AGGAGTTCAC ACGCCTCAAA
GAGGCGCTAG AGAAGTCCGA GGCTCGCCGC AAGGAGCTGG AGGAGAAGAT GGTGTCCCTG
CTGCAGGAGA AGAATGACCT GCAGCTCCAA GTGCAGGCGG AACAAGACAA CCTGGCAGAT
GCTGAGGAGC GCTGTGATCA GCTGATCAAA AACAAGATTC AGCTGGAGGC CAAGGTGAAG
GAGATGAACG AGAGGCTGGA GGATGAGGAG GAGATGAATG CTGAGCTCAC TGCCAAGAAG
CGCAAGCTGG AAGATGAGTG CTCAGAGCTC AAAAGGGACA TCGATGATCT GGAGCTGACA
CTGGCCAAAG TGGAGAAGGA GAAACACGCA ACAGAGAACA AGGTGAAAAA CCTGACAGAG
GAGATGGCTG GGCTGGATGA GATCATTGCC AAGCTGACCA AGGAGAAGAA AGCTCTGCAA
GAGGCCCACC AACAGGCTCT GGATGACCTT CAGGCCGAGG AGGACAAGGT CAACACCCTG
ACTAAGGCCA AAGTCAAGCT GGAGCAGCAA GTGGATGATC TGGAAGGATC CCTGGAGCAA
GAGAAGAAGG TGCGCATGGA CCTGGAGCGA GCGAAGCGGA AGCTGGAGGG CGACCTGAAG
CTGACCCAGG AGAGCATCAT GGACCTGGAG AATGACAAGC AGCAGCTGGA TGAGCGGCTG
AAAAAAAAAG ACTTTGAGCT GAATGCTCTC AACGCAAGGA TTGAGGATGA ACAGGCCCTC
GGCAGCCAGC TGCAGAAGAA GCTCAAGGAG CTTCAGGCAC GCATCGAGGA GCTGGAGGAG
GAGCTGGAGG CCGAGCGCAC CGCCAGGGCT AAGGTGGAGA AGCTGCGCTC AGACCTGTCT
CGGGAGCTGG AGGAGATCAG CGAGCGGCTG GAAGAGGCCG GCGGGGCCAC GTCCGTGCAG
ATCGAGATGA ACAAGAAGCG CGAGGCCGAG TTCCAGAAGA TGCGGCGGGA CCTGGAGGAG
GCCACGCTGC AGCACGAGGC CACTGCCGCG GCCCTGCGCA AGAAGCACGC CGACAGCGTG
GCCGAGCTGG GCGAGCAGAT CGACAACCTG CAGCGGGTGA AGCAGAAGCT GGAGAAGGAG
AAGAGCGAGT TCAAGCTGGA GCTGGATGAC GTCACCTCCA ACATGGAGCA GATCATCAAG
GCCAAGGCTA ACCTGGAGAA GATGTGCCGG ACCTTGGAAG ACCAGATGAA TGAGCACCGG
AGCAAGGCGG AGGAGACCCA GCGTTCTGTC AACGACCTCA CCAGCCAGCG GGCCAAGTTG
CAAACCGAGA ATGGTGAGCT GTCCCGGCAG CTGGATGAGA AGGAGGCACT GATCTCCCAG
CTGACCCGAG GCAAGCTCAC CTACACCCAG CAGCTGGAGG ACCTCAAGAG GCAGCTGGAG
GAGGAGGTTA AGGCGAAGAA CGCCCTGGCC CACGCACTGC AGTCGGCCCG GCATGACTGC
GACCTGCTGC GGGAGCAGTA CGAGGAGGAG ACGGAGGCCA AGGCCGAGCT GCAGCGCGTC
CTTTCCAAGG CCAACTCGGA GGTGGCCCAG TGGAGGACCA AGTATGAGAC GGACGCCATT
CAGCGGACTG AGGAGCTCGA GGAGGCCAAG AAGAAGCTGG CCCAGCGGCT GCAGGAAGCT
GAGGAGGCCG TGGAGGCTGT TAATGCCAAG TGCTCCTCGC TGGAGAAGAC CAAGCACCGG
CTACAGAATG AGATCGAGGA CTTGATGGTG GACGTAGAGC GCTCCAATGC TGCTGCTGCA
GCCCTGGACA AGAAGCAGAG GAACTTCGAC AAGATCCTGG CCGAGTGGAA GCAGAAGTAT
GAGGAGTCGC AGTCGGAGCT GGAGTCCTCG CAGAAGGAGG CTCGCTCCCT CAGCACAGAG
CTCTTCAAAC TCAAGAACGC CTATGAGGAG TCCCTGGAAC ATCTGGAGAC CTTCAAGCGG
GAGAACAAAA ACCTGCAGGA GGAGATCTCC GACTTGACTG AGCAGTTGGG TTCCAGCGGA
AAGACTATCC ATGAGCTGGA GAAGGTCCGA AAGCAGCTGG AGGCCGAGAA GATGGAGCTG
CAGTCAGCCC TGGAGGAGGC CGAGGCCTCC CTGGAGCACG AGGAGGGCAA GATCCTCCGG
GCCCAGCTGG AGTTCAACCA GATCAAGGCA GAGATCGAGC GGAAGCTGGC AGAGAAGGAC
GAGGAGATGG AACAGGCCAA GCGCAACCAC CTGCGGGTGG TGGACTCGCT GCAGACCTCC
CTGGACGCAG AGACACGCAG CCGCAACGAG GCCCTGAGGG TGAAGAAGAA GATGGAAGGA
GACCTCAATG AGATGGAGAT CCAGCTCAGC CACGCCAACC GCATGGCCGC CGAGGCCCAG
AAGCAAGTCA AGAGCCTCCA GAGCTTGTTG AAGGACACCC AGATTCAGCT GGACGATGCA
GTCCGTGCCA ACGACGACCT GAAGGAGAAC ATCGCCATCG TGGAGCGGCG CAACAACCTG
CTGCAGGCTG AGCTGGAGGA GTTGCGTGCC GTGGTGGAGC AGACAGAGCG GTCCCGGAAG
CTGGCGGAGC AGGAGCTGAT TGAGACTAGT GAGCGGGTGC AGCTGCTGCA TTCCCAGAAC
ACCAGCCTCA TCAACCAGAA GAAGAAGATG GATGCTGACC TGTCCCAGCT CCAGACTGAA
GTGGAGGAGG CAGTGCAGGA GTGCAGGAAT GCTGAGGAGA AGGCCAAGAA GGCCATCACG
GATGCCGCCA TGATGGCAGA GGAGCTGAAG AAGGAGCAGG ACACCAGCGC CCACCTGGAG
CGCATGAAGA AGAACATGGA ACAGACCATT AAGGACCTGC AGCACCGGCT GGACGAAGCC
GAGCAGATCG CCCTCAAGGG CGGCAAGAAG CAGCTGCAGA AGCTGGAAGC GCGGGTGCGG
GAGCTGGAGA ATGAGCTGGA GGCCGAGCAG AAGCGCAACG CAGAGTCGGT GAAGGGCATG
AGGAAGAGCG AGCGGCGCAT CAAGGAGCTC ACCTACCAGA CGGAGGAGGA CAGGAAAAAC
CTGCTGCGGC TGCAGGACCT GGTAGACAAG CTGCAGCTAA AGGTCAAGGC CTACAAGCGC
CAGGCCGAGG AGGCGGAGGA GCAAGCCAAC ACCAACCTGT CCAAGTTCCG CAAGGTGCAG
CACGAGCTGG ATGAGGCAGA GGAGCGGGCG GACATCGCCG AGTCCCAGGT CAACAAGCTG
CGGGCCAAGA GCCGTGACAT TGGCACGAAG GGCTTGAATG AGGAGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_000248.2
CDS132..5939
Misc Feature(1)102..104(+)
Misc Feature(2)231..356(+)
Misc Feature(3)369..2465(+)
Misc Feature(4)426..2429(+)
Misc Feature(5)507..1529(+)
Misc Feature(6)507..533(+)
Misc Feature(7)663..686(+)
Misc Feature(8)828..860(+)
Misc Feature(9)1512..1529(+)
Misc Feature(10)1599..1670(+)
Misc Feature(11)2094..2162(+)
Misc Feature(12)2220..2249(+)
Misc Feature(13)2256..2429(+)
Misc Feature(14)2400..2444(+)
Misc Feature(15)2670..3260(+)
Misc Feature(16)2766..3254(+)
Misc Feature(17)3333..5909(+)
Misc Feature(18)3525..4010(+)
Misc Feature(19)3825..4403(+)
Misc Feature(20)3831..4043(+)
Exon (1)1..67
Gene:MYH7
Gene Synonym:
Exon (2)68..123
Gene:MYH7
Gene Synonym:
Exon (3)124..332
Gene:MYH7
Gene Synonym:
Exon (4)333..476
Gene:MYH7
Gene Synonym:
Exon (5)477..633
Gene:MYH7
Gene Synonym:
Exon (6)634..661
Gene:MYH7
Gene Synonym:
Exon (7)662..770
Gene:MYH7
Gene Synonym:
Exon (8)771..863
Gene:MYH7
Gene Synonym:
Exon (9)864..927
Gene:MYH7
Gene Synonym:
Exon (10)928..1026
Gene:MYH7
Gene Synonym:
Exon (11)1027..1130
Gene:MYH7
Gene Synonym:
Exon (12)1131..1269
Gene:MYH7
Gene Synonym:
Exon (13)1270..1388
Gene:MYH7
Gene Synonym:
Exon (14)1389..1538
Gene:MYH7
Gene Synonym:
Exon (15)1539..1709
Gene:MYH7
Gene Synonym:
Exon (16)1710..2019
Gene:MYH7
Gene Synonym:
Exon (17)2020..2087
Gene:MYH7
Gene Synonym:
Exon (18)2088..2175
Gene:MYH7
Gene Synonym:
Exon (19)2176..2293
Gene:MYH7
Gene Synonym:
Exon (20)2294..2417
Gene:MYH7
Gene Synonym:
Exon (21)2418..2554
Gene:MYH7
Gene Synonym:
Exon (22)2555..2810
Gene:MYH7
Gene Synonym:
Exon (23)2811..3053
Gene:MYH7
Gene Synonym:
Exon (24)3054..3230
Gene:MYH7
Gene Synonym:
Exon (25)3231..3376
Gene:MYH7
Gene Synonym:
Exon (26)3377..3467
Gene:MYH7
Gene Synonym:
Exon (27)3468..3857
Gene:MYH7
Gene Synonym:
Exon (28)3858..3984
Gene:MYH7
Gene Synonym:
Exon (29)3985..4103
Gene:MYH7
Gene Synonym:
Exon (30)4104..4300
Gene:MYH7
Gene Synonym:
Exon (31)4301..4484
Gene:MYH7
Gene Synonym:
Exon (32)4485..4650
Gene:MYH7
Gene Synonym:
Exon (33)4651..4775
Gene:MYH7
Gene Synonym:
Exon (34)4776..5084
Gene:MYH7
Gene Synonym:
Exon (35)5085..5288
Gene:MYH7
Gene Synonym:
Exon (36)5289..5414
Gene:MYH7
Gene Synonym:
Exon (37)5415..5690
Gene:MYH7
Gene Synonym:
Exon (38)5691..5786
Gene:MYH7
Gene Synonym:
Exon (39)5787..5921
Gene:MYH7
Gene Synonym:
Exon (40)5922..6055
Gene:MYH7
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_000257
Organism Homo sapiens (human)
Definition Homo sapiens myosin, heavy chain 7, cardiac muscle, beta (MYH7), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_000257

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
3481
3541
3601
3661
3721
3781
3841
3901
3961
4021
4081
4141
4201
4261
4321
4381
4441
4501
4561
4621
4681
4741
4801
4861
4921
4981
5041
5101
5161
5221
5281
5341
5401
5461
5521
5581
5641
5701
5761
ATGGGAGATT CGGAGATGGC AGTCTTTGGG GCTGCCGCCC CCTACCTGCG CAAGTCAGAG 
AAGGAGCGGC TAGAAGCGCA GACCAGGCCT TTTGACCTCA AGAAGGATGT CTTCGTGCCT
GATGACAAAC AGGAGTTTGT CAAGGCCAAG ATCGTGTCTC GAGAGGGTGG CAAAGTCACT
GCCGAGACCG AGTATGGCAA GACAGTGACC GTGAAGGAGG ACCAGGTGAT GCAGCAGAAC
CCACCCAAGT TCGACAAAAT CGAGGACATG GCCATGCTGA CCTTCCTGCA TGAGCCCGCG
GTGCTCTACA ACCTCAAGGA TCGCTACGGC TCCTGGATGA TCTACACCTA CTCGGGCCTC
TTCTGTGTCA CCGTCAACCC TTACAAGTGG CTGCCGGTGT ACACTCCTGA GGTGGTGGCT
GCCTACCGGG GCAAGAAGAG GAGCGAGGCC CCGCCCCACA TCTTCTCCAT CTCCGACAAC
GCCTATCAGT ACATGCTGAC AGACAGAGAA AACCAGTCCA TCCTGATCAC CGGAGAATCC
GGAGCAGGGA AGACAGTCAA CACCAAGAGG GTCATCCAGT ACTTTGCTGT TATTGCAGCC
ATTGGGGACC GCAGCAAGAA GGACCAGAGC CCGGGCAAGG GCACCCTGGA GGACCAGATC
ATCCAGGCCA ACCCTGCTCT GGAGGCCTTT GGCAATGCCA AGACCGTCCG GAACGACAAC
TCCTCCCGCT TCGGGAAATT CATTCGAATT CATTTTGGGG CAACAGGAAA GTTGGCATCT
GCAGACATAG AGACCTATCT TCTGGAAAAA TCCAGAGTTA TTTTCCAGCT GAAAGCAGAG
AGAGATTATC ACATTTTCTA CCAAATCCTG TCTAACAAAA AGCCTGAGCT GCTGGACATG
CTGCTGATCA CCAACAACCC CTACGATTAT GCATTCATCT CCCAAGGAGA GACCACCGTG
GCCTCCATTG ATGACGCTGA GGAGCTCATG GCCACTGATA ACGCTTTTGA TGTGCTGGGC
TTCACTTCAG AGGAGAAAAA CTCCATGTAT AAGCTGACAG GCGCCATCAT GCACTTTGGA
AACATGAAGT TCAAGCTGAA GCAGCGGGAG GAGCAGGCGG AGCCAGACGG CACTGAAGAG
GCTGACAAGT CTGCCTACCT CATGGGGCTG AACTCAGCCG ACCTGCTCAA GGGGCTGTGC
CACCCTCGGG TGAAAGTGGG CAATGAGTAC GTCACCAAGG GGCAGAATGT CCAGCAGGTG
ATATATGCCA CTGGGGCACT GGCCAAGGCA GTGTATGAGA GGATGTTCAA CTGGATGGTG
ACGCGCATCA ATGCCACCCT GGAGACCAAG CAGCCACGCC AGTACTTCAT AGGAGTCCTG
GACATCGCTG GCTTCGAGAT CTTCGATTTC AACAGCTTTG AGCAGCTCTG CATCAACTTC
ACCAACGAGA AGCTGCAGCA GTTCTTCAAC CACCACATGT TTGTGCTGGA GCAGGAGGAG
TACAAGAAGG AGGGCATCGA GTGGACATTC ATTGACTTTG GCATGGACCT GCAGGCCTGC
ATTGACCTCA TCGAGAAGCC CATGGGCATC ATGTCCATCC TGGAAGAGGA GTGCATGTTC
CCCAAGGCCA CCGACATGAC CTTCAAGGCC AAGCTGTTTG ACAACCACCT GGGCAAATCC
GCCAACTTCC AGAAGCCACG CAATATCAAG GGGAAGCCTG AAGCCCACTT CTCCCTGATC
CACTATGCCG GCATCGTGGA CTACAACATC ATTGGCTGGC TGCAGAAGAA CAAGGATCCT
CTCAATGAGA CTGTCGTGGG CTTGTATCAG AAGTCTTCCC TCAAGCTGCT CAGCACCCTG
TTTGCCAACT ATGCTGGGGC TGATGCGCCT ATTGAGAAGG GCAAAGGCAA GGCCAAGAAA
GGCTCGTCCT TTCAGACTGT GTCAGCTCTG CACAGGGAAA ATCTGAACAA GCTGATGACC
AACTTGCGCT CCACCCATCC CCACTTTGTA CGTTGTATCA TCCCTAATGA GACAAAGTCT
CCAGGGGTGA TGGACAACCC CCTGGTCATG CACCAGCTGC GCTGCAATGG TGTGCTGGAG
GGCATCCGCA TCTGCAGGAA AGGCTTCCCC AACCGCATCC TCTACGGGGA CTTCCGGCAG
AGGTATCGCA TCCTGAACCC AGCGGCCATC CCTGAGGGAC AGTTCATTGA TAGCAGGAAG
GGGGCAGAGA AGCTGCTCAG CTCCCTGGAC ATTGATCACA ACCAGTACAA GTTTGGCCAC
ACCAAGGTGT TCTTCAAGGC CGGGCTGCTG GGGCTGCTGG AGGAAATGAG GGACGAGAGG
CTGAGCCGCA TCATCACGCG TATCCAGGCC CAGTCCCGAG GTGTGCTCGC CAGAATGGAG
TACAAAAAGC TGCTGGAACG TAGAGACTCC CTGCTGGTAA TCCAGTGGAA CATTCGGGCC
TTCATGGGGG TCAAGAATTG GCCCTGGATG AAGCTCTACT TCAAGATCAA GCCGCTGCTG
AAGAGTGCAG AAAGAGAGAA GGAGATGGCC TCCATGAAGG AGGAGTTCAC ACGCCTCAAA
GAGGCGCTAG AGAAGTCCGA GGCTCGCCGC AAGGAGCTGG AGGAGAAGAT GGTGTCCCTG
CTGCAGGAGA AGAATGACCT GCAGCTCCAA GTGCAGGCGG AACAAGACAA CCTGGCAGAT
GCTGAGGAGC GCTGTGATCA GCTGATCAAA AACAAGATTC AGCTGGAGGC CAAGGTGAAG
GAGATGAACG AGAGGCTGGA GGATGAGGAG GAGATGAATG CTGAGCTCAC TGCCAAGAAG
CGCAAGCTGG AAGATGAGTG CTCAGAGCTC AAAAGGGACA TCGATGATCT GGAGCTGACA
CTGGCCAAAG TGGAGAAGGA GAAACACGCA ACAGAGAACA AGGTGAAAAA CCTGACAGAG
GAGATGGCTG GGCTGGATGA GATCATTGCC AAGCTGACCA AGGAGAAGAA AGCTCTGCAA
GAGGCCCACC AACAGGCTCT GGATGACCTT CAGGCCGAGG AGGACAAGGT CAACACCCTG
ACTAAGGCCA AAGTCAAGCT GGAGCAGCAA GTGGATGATC TGGAAGGATC CCTGGAGCAA
GAGAAGAAGG TGCGCATGGA CCTGGAGCGA GCGAAGCGGA AGCTGGAGGG CGACCTGAAG
CTGACCCAGG AGAGCATCAT GGACCTGGAG AATGACAAGC AGCAGCTGGA TGAGCGGCTG
AAAAAAAAAG ACTTTGAGCT GAATGCTCTC AACGCAAGGA TTGAGGATGA ACAGGCCCTC
GGCAGCCAGC TGCAGAAGAA GCTCAAGGAG CTTCAGGCAC GCATCGAGGA GCTGGAGGAG
GAGCTGGAGG CCGAGCGCAC CGCCAGGGCT AAGGTGGAGA AGCTGCGCTC AGACCTGTCT
CGGGAGCTGG AGGAGATCAG CGAGCGGCTG GAAGAGGCCG GCGGGGCCAC GTCCGTGCAG
ATCGAGATGA ACAAGAAGCG CGAGGCCGAG TTCCAGAAGA TGCGGCGGGA CCTGGAGGAG
GCCACGCTGC AGCACGAGGC CACTGCCGCG GCCCTGCGCA AGAAGCACGC CGACAGCGTG
GCCGAGCTGG GCGAGCAGAT CGACAACCTG CAGCGGGTGA AGCAGAAGCT GGAGAAGGAG
AAGAGCGAGT TCAAGCTGGA GCTGGATGAC GTCACCTCCA ACATGGAGCA GATCATCAAG
GCCAAGGCTA ACCTGGAGAA GATGTGCCGG ACCTTGGAAG ACCAGATGAA TGAGCACCGG
AGCAAGGCGG AGGAGACCCA GCGTTCTGTC AACGACCTCA CCAGCCAGCG GGCCAAGTTG
CAAACCGAGA ATGGTGAGCT GTCCCGGCAG CTGGATGAGA AGGAGGCACT GATCTCCCAG
CTGACCCGAG GCAAGCTCAC CTACACCCAG CAGCTGGAGG ACCTCAAGAG GCAGCTGGAG
GAGGAGGTTA AGGCGAAGAA CGCCCTGGCC CACGCACTGC AGTCGGCCCG GCATGACTGC
GACCTGCTGC GGGAGCAGTA CGAGGAGGAG ACGGAGGCCA AGGCCGAGCT GCAGCGCGTC
CTTTCCAAGG CCAACTCGGA GGTGGCCCAG TGGAGGACCA AGTATGAGAC GGACGCCATT
CAGCGGACTG AGGAGCTCGA GGAGGCCAAG AAGAAGCTGG CCCAGCGGCT GCAGGAAGCT
GAGGAGGCCG TGGAGGCTGT TAATGCCAAG TGCTCCTCGC TGGAGAAGAC CAAGCACCGG
CTACAGAATG AGATCGAGGA CTTGATGGTG GACGTAGAGC GCTCCAATGC TGCTGCTGCA
GCCCTGGACA AGAAGCAGAG GAACTTCGAC AAGATCCTGG CCGAGTGGAA GCAGAAGTAT
GAGGAGTCGC AGTCGGAGCT GGAGTCCTCG CAGAAGGAGG CTCGCTCCCT CAGCACAGAG
CTCTTCAAAC TCAAGAACGC CTATGAGGAG TCCCTGGAAC ATCTGGAGAC CTTCAAGCGG
GAGAACAAAA ACCTGCAGGA GGAGATCTCC GACTTGACTG AGCAGTTGGG TTCCAGCGGA
AAGACTATCC ATGAGCTGGA GAAGGTCCGA AAGCAGCTGG AGGCCGAGAA GATGGAGCTG
CAGTCAGCCC TGGAGGAGGC CGAGGCCTCC CTGGAGCACG AGGAGGGCAA GATCCTCCGG
GCCCAGCTGG AGTTCAACCA GATCAAGGCA GAGATCGAGC GGAAGCTGGC AGAGAAGGAC
GAGGAGATGG AACAGGCCAA GCGCAACCAC CTGCGGGTGG TGGACTCGCT GCAGACCTCC
CTGGACGCAG AGACACGCAG CCGCAACGAG GCCCTGAGGG TGAAGAAGAA GATGGAAGGA
GACCTCAATG AGATGGAGAT CCAGCTCAGC CACGCCAACC GCATGGCCGC CGAGGCCCAG
AAGCAAGTCA AGAGCCTCCA GAGCTTGTTG AAGGACACCC AGATTCAGCT GGACGATGCA
GTCCGTGCCA ACGACGACCT GAAGGAGAAC ATCGCCATCG TGGAGCGGCG CAACAACCTG
CTGCAGGCTG AGCTGGAGGA GTTGCGTGCC GTGGTGGAGC AGACAGAGCG GTCCCGGAAG
CTGGCGGAGC AGGAGCTGAT TGAGACTAGT GAGCGGGTGC AGCTGCTGCA TTCCCAGAAC
ACCAGCCTCA TCAACCAGAA GAAGAAGATG GATGCTGACC TGTCCCAGCT CCAGACTGAA
GTGGAGGAGG CAGTGCAGGA GTGCAGGAAT GCTGAGGAGA AGGCCAAGAA GGCCATCACG
GATGCCGCCA TGATGGCAGA GGAGCTGAAG AAGGAGCAGG ACACCAGCGC CCACCTGGAG
CGCATGAAGA AGAACATGGA ACAGACCATT AAGGACCTGC AGCACCGGCT GGACGAAGCC
GAGCAGATCG CCCTCAAGGG CGGCAAGAAG CAGCTGCAGA AGCTGGAAGC GCGGGTGCGG
GAGCTGGAGA ATGAGCTGGA GGCCGAGCAG AAGCGCAACG CAGAGTCGGT GAAGGGCATG
AGGAAGAGCG AGCGGCGCAT CAAGGAGCTC ACCTACCAGA CGGAGGAGGA CAGGAAAAAC
CTGCTGCGGC TGCAGGACCT GGTAGACAAG CTGCAGCTAA AGGTCAAGGC CTACAAGCGC
CAGGCCGAGG AGGCGGAGGA GCAAGCCAAC ACCAACCTGT CCAAGTTCCG CAAGGTGCAG
CACGAGCTGG ATGAGGCAGA GGAGCGGGCG GACATCGCCG AGTCCCAGGT CAACAAGCTG
CGGGCCAAGA GCCGTGACAT TGGCACGAAG GGCTTGAATG AGGAGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

Genetic variations of beta-MYH7 in Venezuelan patients with hypertrophic cardiomyopathy
Invest Clin 55 (1), 23-31 (2014)
Rodriguez,R., Guerrero,D., Rivas,Y., Lacruz,A. and Flores,Y.


book

The hypertrophic cardiomyopathy myosin mutation R453C alters ATP binding and hydrolysis of human cardiac beta-myosin
J. Biol. Chem. 289 (8), 5158-5167 (2014)
Bloemink M, Deacon J, Langer S, Vera C, Combs A, Leinwand L and Geeves MA.


book

All-atom molecular dynamics simulations of actin-myosin interactions: a comparative study of cardiac alpha myosin, beta myosin, and fast skeletal muscle myosin
Biochemistry 52 (47), 8393-8405 (2013)
Li M and Zheng W.


book

Hereditary myosin myopathies
Neuromuscul. Disord. 17 (5), 355-367 (2007)
Oldfors A.


book

Hypertrophic Cardiomyopathy Overview
(in) Pagon RA, Adam MP, Ardinger HH, Bird TD, Dolan CR, Fong CT, Smith RJH and Stephens K (Eds.); GENEREVIEWS(R); (1993)
Cirino,A.L. and Ho,C.


book

Laing Distal Myopathy
(in) Pagon RA, Adam MP, Ardinger HH, Bird TD, Dolan CR, Fong CT, Smith RJH and Stephens K (Eds.); GENEREVIEWS(R); (1993)
Lamont,P., Wallefeld,W. and Laing,N.G.


book

Dilated Cardiomyopathy Overview
(in) Pagon RA, Adam MP, Ardinger HH, Bird TD, Dolan CR, Fong CT, Smith RJH and Stephens K (Eds.); GENEREVIEWS(R); (1993)
Hershberger,R.E. and Morales,A.


book

Congenital Fiber-Type Disproportion
(in) Pagon RA, Adam MP, Ardinger HH, Bird TD, Dolan CR, Fong CT, Smith RJH and Stephens K (Eds.); GENEREVIEWS(R); (1993)
DeChene,E.T., Kang,P.B. and Beggs,A.H.


book

Dinucleotide repeat polymorphism at the human cardiac beta-myosin heavy chain gene (HMSYHCO1) locus
Hum. Mol. Genet. 1 (2), 136 (1992)
Warlick CA, Ramachandra S, Mishra S and Donis-Keller H.


book

Dinucleotide repeat polymorphism at the human gene for cardiac beta-myosin heavy chain (MYH6)
Hum. Mol. Genet. 1 (1), 64 (1992)
Fougerousse F, Dufour C, Roudaut C and Beckmann JS.


 
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